Thermopressure dual-sensitive, high-strength and high-toughness multifunctional nanocomposite hydrogel and preparation method thereof

Abstract

This invention discloses a temperature- and pressure-sensitive, high-strength, and tough multifunctional nanocomposite hydrogel and its preparation method, belonging to the field of hydrogel technology. The invention first isolates tunicin from sea squirts and hydrolyzes it with acid to obtain sea squirt nanocellulose. Hydroxypropyl cellulose is dissolved in deionized water, sodium dodecyl sulfate is added, and the mixture is sonicated until dissolved. Then, octadecyl methacrylate, acrylamide, sea squirt nanocellulose suspension, and MXene / Ag nanosheet dispersion are added sequentially, and the mixture is mixed with an initiator. Emulsion polymerization is then performed to obtain the nanocomposite hydrogel product. The reaction disclosed in this invention is easy to operate and operates under mild conditions. Furthermore, the nanocomposite hydrogel prepared by the method disclosed in this invention exhibits high efficiency in multiple sensitivities (temperature and pressure), high strength, and excellent biocompatibility, showing broad application prospects in disease diagnosis and daily monitoring in the medical and pharmaceutical fields.

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