Application of nutritional composition in preparation of products for improving learning, memory and cognitive competence

By targeting the hippocampus with a nutritional composition of Bifidobacterium lactis subsp. CP-9 and 3'-sialic acid lactose, myelin sheath development and regeneration are promoted, overcoming the safety and efficacy limitations of existing technologies for improving learning and memory abilities, and achieving significant enhancement of cognitive function.

CN122250672APending Publication Date: 2026-06-23AUSNUTRIA DAIRY CHINA
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Patent Information

Application Number
CN202610748563.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-28
Publication Date
2026-06-23

AI Technical Summary

Technical Problem

Existing technologies for improving learning and memory abilities have safety concerns, limited effectiveness, and a narrow range of applicable populations. Drug treatments have significant side effects, cognitive training results vary greatly from person to person and are difficult to meet the needs for rapid improvement, and the potential of nutritional supplements such as probiotics in regulating cognitive function has not been fully realized.

Method used

Using a nutritional composition of Bifidobacterium lactis subsp. CP-9 and 3'-sialic acid lactose, this study promotes myelin development, maintenance, regeneration, and repair by targeting the hippocampus, enhances memory retention, regulates the gene expression of oligodendrocyte transcription factor 2, myelin basic protein, and brain-derived neurotrophic factor, and improves the neuroplasticity of the central nervous system.

Benefits of technology

It significantly enhances learning, memory, and cognitive abilities, reduces learning and memory errors, achieves dual regulation of myelination and neurotrophic function in the hippocampus, provides safe and effective cognitive function intervention, and is suitable for different populations.

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Abstract

The invention provides an application of a nutritional composition in preparation of a product for improving learning, memory and cognitive competence. The nutritional composition comprises Bifidobacterium animalis subsp. Lactis CP-9 and 3 '-sialic acid lactose. Bifidobacterium animalis subsp. Lactis CP-9 and 3 '-sialic acid lactose can synergistically enhance the memory retention ability of a body, reduce the learning and memory error degree and up-regulate the expression of an oligodendrocyte transcription factor 2 coding gene, a myelin sheath basic protein coding gene and a brain-derived neurotrophic factor coding gene; dual regulation and control of myelin sheath formation and neurotrophy in a hippocampus area in the brain are realized, and neuroplasticity of a central nervous system is synergistically improved through an intestine-brain axis pathway, so that learning, memory and cognitive functions of an organism are dual improved from behavioristics and molecular levels.
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