A composition having a laxative effect, and a method for preparing and using the same

By preparing a dragon fruit polysaccharide composition, constipation problems were solved, the intestinal barrier function was enhanced, gastrointestinal motility was restored, and intestinal microbiota was regulated, achieving the effect of lubricating the intestines and relieving constipation, while avoiding drug dependence and side effects.

CN122398848APending Publication Date: 2026-07-17GUANGDONG MODERN HANFANG TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GUANGDONG MODERN HANFANG TECH CO LTD
Filing Date
2026-05-27
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Constipation is a common problem, and existing drug treatments have side effects and can lead to dependence. There is a lack of safe and effective laxative combinations.

Method used

Using dragon fruit polysaccharide (HPUP) as the main component, a composition was prepared through extraction and purification processes, including aqueous solvent extraction, precipitation, ion exchange column chromatography and non-ionic gel chromatography separation, to enhance intestinal barrier function, restore gastrointestinal motility balance and regulate intestinal microbiota.

Benefits of technology

It effectively relieves constipation, improves intestinal barrier function, restores the microbial community structure of cecal contents, increases short-chain fatty acid content, enhances intestinal immunity, and achieves the effect of lubricating the intestines and promoting bowel movements.

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Abstract

本发明公开一种具有润肠通便作用的组合物及其制备方法和应用。本发明的组合物能够改善或恢复肠道屏障完整性、提高结肠紧密连接蛋白的表达量、调节肠道微生物有益菌群的比例、提高短链脂肪酸含量、提升胃肠动力、调节肠道氧化应激、提高受试者粪便含水量及肠道转运率、减轻肠道组织损伤等,从而具有润肠通便作用。此外,本发明的组合物具有安全性高、疗效好等优点。
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