Liquid chromatography peak baseline correction method, apparatus, storage medium, and electronic device
By locating candidate peaks and splitting fusion peaks in liquid chromatography, constructing and correcting the baseline of sub-peaks, the problem of baseline misjudgment under negative peak interference is solved, and the accuracy of baseline correction and peak parameter calculation of liquid chromatography peaks is improved.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- ACCHROM TECH CO LTD
- Filing Date
- 2026-06-01
- Publication Date
- 2026-07-17
AI Technical Summary
Existing liquid chromatography peak baseline correction methods are prone to baseline crossing when negative peaks are present, leading to incorrect peak cluster segmentation and affecting the accuracy of peak parameter calculations and quantitative analysis results.
By employing candidate peak localization, fusion peak splitting, and sub-peak correction methods, an initial baseline for the fusion peak is constructed and split into multiple sub-peaks. Initial baseline corrections are then performed on each sub-peak to ensure the accuracy of the peak endpoint and starting point.
It improves the accuracy of peak baseline correction in liquid chromatography, reduces misjudgment under negative peak interference, and enhances the accuracy of peak parameter calculation and the reliability of integration results.
Smart Images
Figure CN122409937A_ABST