Hematopoietic stem cell cryopreservation bag

Abstract

The utility model discloses a hematopoietic stem cell cryopreservation bag, and relates to the technical field of medical cryopreservation bags. The protective front shell and the protective rear shell are assembled through the inserting groove and the inserting rod, the tail of the cryopreservation bag body is placed on the clamping plate and the auxiliary extrusion roller, when the cryopreservation bag body needs to be used, the sealing plug is rotated, the sealing plug is screwed out of the drainage pipe, and then the cryopreservation bag body can be used. Hematopoietic stem cells needing to be cryopreserved enter the cryopreservation bag body through the drainage tube for cryopreservation, and the protective shell protects the cryopreservation bag body and prevents the cryopreservation bag body from being damaged; when the hematopoietic stem cells need to be used, the hematopoietic stem cells are firstly subjected to thawing treatment, a sealing plug is unscrewed, then a movable block is pushed along an extrusion groove, a transverse plate drives a sliding block on a fixing frame to move along a rail groove, a main extrusion roller and an auxiliary extrusion roller are matched with each other, and the hematopoietic stem cells in the cryopreservation bag body are extruded out; the hematopoietic stem cells are prevented from being left in the cryopreservation bag body to cause waste, and meanwhile the outflow speed of the hematopoietic stem cells is increased.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical cryopreservation bags, in particular to a hematopoietic stem cell cryopreservation bag. Background Art

[0002] Hematopoietic stem cells are usually stored in a low-temperature refrigerator / liquid nitrogen tank at -85°C or -196°C, depending on the required storage period. For stem cells with a short period from collection to use (less than 6 months), they are usually frozen in a deep-low temperature refrigerator at -85°C. At present, there is no unified operating specification for the cryopreservation of such stem cells, and the preservation boxes selected by each unit are also different. The existing technology uses cryopreservation bags to store stem cells, which is easily damaged due to compression of the bag body, and the inner bag body and outer bag body of most cryopreservation bags are integrally formed and made of hard materials. In the process of pouring out the hematopoietic stem cell liquid, the cryopreservation bag needs to be inverted for a period of time, and the inner wall of the inner bag body is easy to adhere to the cell liquid, and the liquid extraction process is not convenient enough. Therefore, a hematopoietic stem cell cryopreservation bag is proposed. Utility Model Content

[0003] The utility model aims to provide a hematopoietic stem cell cryopreservation bag to solve the existing problems.

[0004] In order to solve the above technical problems, the utility model is realized by the following technical solutions:

[0005] The utility model discloses a hematopoietic stem cell freezing bag, comprising a protective shell and a freezing bag body, wherein the protective shell comprises a protective front shell and a protective rear shell, slots are arranged on both sides of a surface of the protective front shell, and insertion rods are arranged on both sides of a surface of the protective rear shell, clamping plates are arranged at the bottom of the protective front shell and the protective rear shell, and a card slot and a corresponding card strip are arranged on one surface of the two clamping plates, respectively, track grooves are arranged on two opposite surfaces of the protective shell, and limiting grooves are arranged on two opposite surfaces of the track groove, and an extrusion mechanism is arranged in the track groove, and the extrusion mechanism comprises a main extrusion roller and an auxiliary extrusion roller, and the main extrusion roller and the auxiliary extrusion roller are arranged on both sides of the main extrusion roller. A fixing frame is provided at both ends, a sliding block is provided at one end of the fixing frame, a limiting block is provided on one surface of the sliding block, a sliding groove and a corresponding block are provided on one surface of two adjacent sliding blocks respectively, a cross plate is provided between the two fixing frames of the main extrusion roller, a movable block is provided on one surface of the cross plate, an extrusion groove is provided on one surface of the protective front shell, the freezing bag body is provided inside the protective shell, a protective tube is provided on the protective shell, a drainage tube is provided on the freezing bag body, a limiting ring is provided at one end of the drainage tube, the drainage tube and the protective tube cooperate with each other, a sealing plug is provided in the drainage tube, and the sealing plug and the protective tube are threadedly matched.

[0006] Furthermore, the position of the insertion rod is adapted to the slot, and the protective front shell is plugged into the protective rear shell.

[0007] Furthermore, an observation window is provided on a surface of the protective rear shell, and a transparent acrylic plate is provided in the observation window.

[0008] Furthermore, the shape and size of the card slot are adapted to the card strip, the card slot and the card strip are snap-fitted together, and the tail of the freezing bag body is arranged between the card slot and the card strip.

[0009] Furthermore, the shape and size of the slider are adapted to the track groove, the slider is slidably matched with the track groove, and the limit block is slidably matched with the limit groove.

[0010] Furthermore, the shape and size of the movable block are adapted to the extrusion groove, and the movable block is slidably matched with the extrusion groove.

[0011] The utility model has the following beneficial effects:

[0012] The utility model places the limiting block on the slider of the auxiliary extrusion roller into the limiting groove of the track groove of the protective rear shell, places the tail of the cryopreservation bag body on the clamping plate and the auxiliary extrusion roller, and slides and engages the sliding groove on the slider of the main extrusion roller with the blocking block, so that the tail of the cryopreservation bag body is fixed between the two clamping plates and is located between the main extrusion roller and the auxiliary extrusion roller. The drainage tube of the cryopreservation bag body is placed in the protective tube position, and then the slot of the protective front shell is aligned with the insertion rod of the protective rear shell. After the protective shell is assembled, the limiting ring limits the drainage tube to prevent the drainage tube from sliding into the protective shell. When the cryopreservation bag body needs to be used, The sealing plug is rotated and matched with the outer wall thread of the protective tube, so that the sealing plug is screwed out of the drainage tube, and the hematopoietic stem cells to be frozen enter the freezing bag body through the drainage tube for freezing and preservation; when the hematopoietic stem cells need to be used, the hematopoietic stem cells are first thawed, and then the sealing plug is unscrewed, and then the movable block is pushed along the extrusion groove, so that the cross plate drives the slider on the fixed frame to move along the track groove, and the main extrusion roller and the auxiliary extrusion roller cooperate with each other to squeeze out the hematopoietic stem cells in the freezing bag body, so as to avoid the waste of hematopoietic stem cells remaining in the freezing bag body and accelerate the outflow of hematopoietic stem cells.

[0013] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0015] Figure 1 This is a schematic diagram of the overall structure of a hematopoietic stem cell freezing bag;

[0016] Figure 2 A top view of a hematopoietic stem cell cryopreservation bag;

[0017] Figure 3 for Figure 2 Middle AA section;

[0018] Figure 4 for Figure 3 Middle BB section;

[0019] Figure 5 for Figure 3 Enlarged view of part C.

[0020] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0021] 0-protective shell, 1-protective front shell, 2-protective rear shell, 3-freezing bag body, 4-slot, 5-insertion rod, 6-clamping plate, 7-card slot, 8-card strip, 9-track slot, 10-limiting slot, 11-main extrusion roller, 12-auxiliary extrusion roller, 13-observation window, 14-fixed frame, 15-slider, 17-slide, 18-card block, 19-cross plate, 20-movable block, 21-extrusion slot, 22-protective tube, 23-drainage tube, 24-limiting ring, 25-sealing plug. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0023] In the description of the present invention, it should be understood that the terms "upper", "middle", "outer", "inner" and the like indicating directions or positional relationships are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the components or elements referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as limitations on the present invention.

[0024] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0025] See also Figure 1-Figure 5 As shown, the utility model is a hematopoietic stem cell freezing bag, including a protective shell 0 and a freezing bag body 3, the protective shell 0 includes a protective front shell 1 and a protective rear shell 2, slots 4 are arranged on both sides of a surface of the protective front shell 1, and plugging rods 5 are arranged on both sides of a surface of the protective rear shell 2. Clamping plates 6 are arranged at the bottom of the protective front shell 1 and the protective rear shell 2, and a card slot 7 and a corresponding card strip 8 are arranged on one surface of the two clamping plates 6, respectively. Track grooves 9 are arranged on both opposite surfaces of the protective shell 0, and limiting grooves 10 are arranged on both opposite surfaces of the track groove 9. An extrusion mechanism is arranged in the track groove 9, and the extrusion mechanism includes a main extrusion roller 11 and an auxiliary extrusion roller 12. Both ends of the main extrusion roller 11 and the auxiliary extrusion roller 12 are provided with fixed A fixed frame 14 is provided with a slider 15 at one end of the fixed frame 14, a limited block is provided on a surface of the slider 15, and a slide groove 17 and a corresponding block 18 are provided on the surfaces of two adjacent sliders 15 respectively. A transverse plate 19 is provided between the two fixed frames 14 of the main extrusion roller 11, and a movable block 20 is provided on a surface of the transverse plate 19. An extrusion groove 21 is provided on a surface of the protective front shell 1. The freezing bag body 3 is arranged inside the protective shell 0, and a protective tube 22 is provided on the protective shell 0. A drainage tube 23 is provided on the freezing bag body 3, and a limited ring 24 is provided at one end of the drainage tube 23. The drainage tube 23 cooperates with the protective tube 22, and a sealing plug 25 is provided in the drainage tube 23, and the sealing plug 25 and the protective tube 22 are threadedly matched.

[0026] The position of the plug rod 5 is adapted to the slot 4 , and the protective front shell 1 is plugged into the protective rear shell 2 .

[0027] A viewing window 13 is disposed on one surface of the protective rear shell 2 , and a transparent acrylic plate is disposed in the viewing window 13 .

[0028] The shape and size of the card slot 7 are adapted to the card strip 8 , the card slot 7 and the card strip 8 are snap-fitted together, and the tail of the freezing bag body 3 is arranged between the card slot 7 and the card strip 8 .

[0029] The shape and size of the slider 15 are adapted to the track groove 9 , the slider 15 and the track groove 9 are slidably matched, and the limit block and the limit groove 10 are slidably matched.

[0030] The shape and size of the movable block 20 are adapted to the extrusion groove 21 , and the movable block 20 and the extrusion groove 21 are slidably matched.

[0031] See also Figure 1-Figure 5 As shown, this embodiment is a method for using a hematopoietic stem cell freezing bag: when using, first put the limiting block on the slider 15 of the auxiliary extrusion roller 12 into the limiting groove 10 of the track groove 9 of the protective rear shell 2, then put the tail of the freezing bag body 3 on the clamping plate 6 and the auxiliary extrusion roller 12, and then slide the groove 17 on the slider 15 of the main extrusion roller 11 and slide and engage with the block 18 to fix the tail of the freezing bag body 3 between the two clamping plates 6 and at the same time be located between the main extrusion roller 11 and the auxiliary extrusion roller 12, place the drainage tube 23 of the freezing bag body 3 at the position of the protective tube 22, then align the slot 4 of the protective front shell 1 with the insertion rod 5 of the protective rear shell 2, and assemble the protective shell 0. The limiting ring 24 limits the drainage tube 23 to prevent the drainage tube 23 from slipping. Fall into the inside of the protective shell 0; when the freezing bag body 3 needs to be used, the sealing plug 25 is rotated, and the sealing plug 25 cooperates with the outer wall thread of the protective tube 22, so that the sealing plug 25 is screwed out from the drainage tube 23, and the hematopoietic stem cells that need to be frozen enter the freezing bag body 3 through the drainage tube 23 for freezing and preservation; when the hematopoietic stem cells need to be used, the hematopoietic stem cells are first thawed, and then the sealing plug 25 is unscrewed, and then the movable block 20 is pushed along the extrusion groove 21, so that the cross plate 19 drives the slider 15 on the fixed frame 14 to move along the track groove 9, and the main extrusion roller 11 and the auxiliary extrusion roller 12 cooperate with each other to squeeze out the hematopoietic stem cells in the freezing bag body 3, so as to avoid the hematopoietic stem cells from remaining in the freezing bag body 3, and at the same time speed up the outflow of hematopoietic stem cells.

[0032] It should be further explained that the protective shell 0 and the extrusion mechanism can be reused to avoid waste.

[0033] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0034] The preferred embodiments of the utility model disclosed above are only used to help explain the utility model. The preferred embodiments do not describe all the details in detail, nor do they limit the utility model to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the utility model, so that technicians in the relevant technical field can well understand and use the utility model. The utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A hematopoietic stem cell cryopreservation bag, comprising a protective shell (0) and a cryopreservation bag body (3), characterized in that: The protective shell (0) comprises a protective front shell (1) and a protective rear shell (2), wherein slots (4) are arranged on both sides of one surface of the protective front shell (1), and insertion rods (5) are arranged on both sides of one surface of the protective rear shell (2), and clamping plates (6) are arranged at the bottom of the protective front shell (1) and the protective rear shell (2), and a card slot (7) and a corresponding card strip (8) are arranged on one surface of the two clamping plates (6), respectively, and track grooves (9) are arranged on two opposite surfaces of the protective shell (0), and limiting grooves (10) are arranged on two opposite surfaces of the track groove (9), and an extrusion mechanism is arranged in the track groove (9), and the extrusion mechanism comprises a main extrusion roller (11) and an auxiliary extrusion roller (12), and both ends of the main extrusion roller (11) and the auxiliary extrusion roller (12) are arranged with a fixing frame (14), and one end of the fixing frame (14) is arranged with a slider (15 ), a limited block is arranged on one surface of the slider (15), and a sliding groove (17) and a corresponding block (18) are arranged on one surface of two adjacent sliders (15), a transverse plate (19) is arranged between the two fixing frames (14) of the main extrusion roller (11), and a movable block (20) is arranged on one surface of the transverse plate (19), and an extrusion groove (21) is arranged on one surface of the protective front shell (1), the freezing bag body (3) is arranged inside the protective shell (0), a protective tube (22) is arranged on the protective shell (0), a drainage tube (23) is arranged on the freezing bag body (3), and a limited ring (24) is arranged at one end of the drainage tube (23), the drainage tube (23) and the protective tube (22) cooperate with each other, a sealing plug (25) is arranged in the drainage tube (23), and the sealing plug (25) and the protective tube (22) are threadedly matched.

2. A hematopoietic stem cell cryopreservation bag according to claim 1, characterized in that: The position of the insertion rod (5) is adapted to the slot (4), and the protective front shell (1) and the protective rear shell (2) are plugged in each other.

3. A hematopoietic stem cell cryopreservation bag according to claim 1, characterized in that: A viewing window (13) is provided on one surface of the protective rear shell (2), and a transparent acrylic plate is provided in the viewing window (13).

4. A hematopoietic stem cell cryopreservation bag according to claim 1, characterized in that: The shape and size of the card slot (7) are adapted to the card strip (8), the card slot (7) and the card strip (8) are snap-fitted together, and the tail of the freezing bag body (3) is arranged between the card slot (7) and the card strip (8).

5. A hematopoietic stem cell cryopreservation bag according to claim 1, characterized in that: The shape and size of the slider (15) are adapted to the track groove (9), the slider (15) and the track groove (9) are slidably matched, and the limit block and the limit groove (10) are slidably matched.

6. A hematopoietic stem cell cryopreservation bag according to claim 1, characterized in that: The shape and size of the movable block (20) are adapted to the extrusion groove (21), and the movable block (20) and the extrusion groove (21) are slidably matched.

Images