Low-temperature preservation device for stem cells

Abstract

The utility model relates to the technical field of stem cell cryopreservation, in particular to a cryopreservation device for stem cells. According to the technical scheme, the device comprises a storage box for storing stem cells and a low-temperature box which is slidably connected in the storage box and is used for creating a low-temperature environment; a pushing mechanism used for automatically controlling the low-temperature box to move is installed in the storage box. The low-temperature box is provided with a sealing mechanism used for improving the sealing performance of the storage box and the low-temperature box. The stem cell storage bottles stored at low temperature can be quickly pushed out of the storage box by the pushing mechanism, so that the problem caused by the fact that a user needs to open a box door and stretch a hand into the box body to take the stem cell storage bottles is effectively solved; meanwhile, the low-temperature box used for storing the stem cells is completely exposed, a user can observe the storage condition of the stem cells more conveniently, the storage box and the low-temperature box are installed in a crossed mode, on one hand, the low-temperature heat preservation effect can be enhanced, energy loss can be reduced, and on the other hand, the sealing effect of the low-temperature box can be improved.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell cryopreservation, in particular to a stem cell cryopreservation device. Background Art

[0002] Some stem cells need to be stored at low temperatures before and after the experiment to enhance the preservation effect of stem cells. Stem cells are generally stored in a low-temperature storage box. In order to facilitate access, the low-temperature storage box generally used is a storage device with a separate door and box body. When taking or placing a stem cell storage bottle, it is generally necessary to open the box door first and take out the storage bottle.

[0003] Traditional stem cell cryopreservation devices use a hinged door and body. When taking out stem cells, you need to open the door and reach into the storage box to take out the storage bottle. During this process, contaminants are easily brought in, causing contamination inside the box. The hinged connection between the door and body can easily lead to poor sealing, which in turn affects the hygiene inside the box, resulting in poor insulation and easy contamination. Summary of the invention

[0004] The utility model aims to solve the problem that the traditional stem cell cryogenic storage device in the background technology adopts a hinged box door and a box body. When taking out the stem cells, it is necessary to open the box door and put the hand into the storage box to take out the storage bottle. In this process, pollutants are easily brought in, causing contamination inside the box body and poor sealing effect. A cryogenic storage device for stem cells is proposed.

[0005] The technical solution of the utility model is as follows: a low-temperature preservation device for stem cells, comprising a storage box for storing stem cells, and also comprising a low-temperature box slidably connected inside the storage box for creating a low-temperature environment; a pushing mechanism for automatically controlling the movement of the low-temperature box is installed in the storage box; and a sealing mechanism for improving the sealing of the storage box and the low-temperature box is arranged on the low-temperature box.

[0006] Preferably, the pushing mechanism includes a motor and a rotating rod, the motor is fixedly mounted on an outer wall of one side of the storage box, two ends of the rotating rod are respectively rotatably connected to the inner wall of the storage box, one end of the rotating rod passes through the storage box and is fixedly connected to the output shaft of the motor, the rotating rod is provided with symmetrically distributed bidirectional thread grooves, and both ends of the bidirectional thread grooves are threadedly connected with sliding blocks adapted thereto, both sliding blocks are rotatably connected with connecting shafts, adjacent ends of the two connecting shafts are rotatably connected with a connecting block, and the connecting block is fixedly connected to an outer wall of one side of the low-temperature box.

[0007] Preferably, the pushing mechanism further comprises a limiting slide groove, which is provided on the inner wall of the storage box and is matched with one end of the sliding block, and the sliding block is limitedly slidably connected in the limiting slide groove.

[0008] Preferably, the sealing mechanism includes a piston bar and an air storage chamber, the air storage chamber is opened on the side of the low-temperature box away from the connecting block, the piston of the motor part plate is connected to the rotating rod, the inner wall of the storage box is fixedly connected with a sealing plate, the sealing plate passes through the low-temperature box and is located on the same horizontal line as the piston bar, the outer wall of the low-temperature box on the side away from the connecting block is opened with a rectangular groove matched with its contour, and an elastic rectangular strip is bonded in the rectangular groove, and the air storage chamber is connected with the rectangular groove.

[0009] Preferably, the sealing mechanism further comprises a rectangular sealing groove, which is formed on the inner wall of the storage box close to the elastic rectangular strip and is matched with the elastic rectangular strip.

[0010] Preferably, the sealing mechanism further comprises a plurality of spring wires, wherein the spring wires are fixedly connected between the air storage chamber and the piston bar, and the moving distance of the piston bar is smaller than the maximum deformation distance of the spring wires.

[0011] Preferably, shock-absorbing blocks for shock absorption are installed at the four corners of the bottom of the storage box, and an elastic gripper for easy gripping and two connecting rings for easy connection with a shoulder strap are fixedly connected to the top of the storage box.

[0012] Preferably, a rectangular frame is fixedly connected to the inner wall of the storage box, and the top of the rectangular frame is fitted with an insulation board for improving the sealing performance, and the insulation board is made of insulation material.

[0013] Compared with the prior art, the utility model has the following beneficial technical effects:

[0014] When the stem cells need to be taken out, it is only necessary to start the pushing mechanism, which can quickly push the low-temperature stored stem cell storage bottle out of the storage box, which not only effectively solves the problem that the user needs to open the box door and reach into the box to take out the stem cells, but also makes it more convenient for the user to observe the storage status of the stem cells when the low-temperature box used to store the stem cells is fully exposed. The cross-installation of the storage box and the low-temperature box can enhance the low-temperature insulation effect and reduce energy loss on the one hand, and improve the sealing effect of the low-temperature box on the other hand;

[0015] When the pushing mechanism drives the low-temperature box to retract and reset, the compressed air generated can, on the one hand, cushion the impact force of the low-temperature box when it moves. At the same time, after the compressed air enters the rectangular groove, it will push the elastic rectangular strip to expand, thereby increasing the abutment effect between the elastic rectangular strip and the inner wall of the storage box, thereby further enhancing the sealing effect between the storage box and the low-temperature box. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1Provide a structural schematic diagram of the utility model;

[0017] Figure 2 A schematic diagram of the structure of the storage box and the low-temperature box in the utility model is given;

[0018] Figure 3 A partial structural cross-sectional schematic diagram of a storage box and a low-temperature box in the utility model is given;

[0019] Figure 4 Provide the utility model Figure 3 Schematic diagram of the enlarged structure of area A.

[0020] Reference numerals: 1. storage box; 2. low temperature box; 3. insulation board; 4. rectangular frame;

[0021] 5. Pushing mechanism; 501. Motor; 502. Rotating rod; 503. Sliding block; 504. Connecting shaft; 505. Connecting block; 506. Limiting slide groove;

[0022] 6. Sealing mechanism; 601. Piston strip; 602. Air storage chamber; 603. Elastic rectangular strip; 604. Spring wire; 605. Sealing plate; 606. Rectangular sealing groove;

[0023] 7. Connecting ring; 8. Elastic gripper; 9. Shock-absorbing block. DETAILED DESCRIPTION

[0024] The technical solution of the utility model is further described below in conjunction with the accompanying drawings and specific embodiments. Example

[0025] like Figure 1-4 As shown, the utility model proposes a low-temperature storage device for stem cells, including a storage box 1 for storing stem cells, and also includes a low-temperature box 2 slidably connected in the storage box 1 for creating a low-temperature environment; a driving mechanism 5 for automatically controlling the movement of the low-temperature box 2 is installed in the storage box 1; and a sealing mechanism 6 for improving the sealing of the storage box 1 and the low-temperature box 2 is arranged on the low-temperature box 2.

[0026] Furthermore, the pushing mechanism 5 includes a motor 501 and a rotating rod 502. The motor 501 is fixedly mounted on an outer wall of one side of the storage box 1. Both ends of the rotating rod 502 are rotatably connected to the inner wall of the storage box 1 respectively. One end of the rotating rod 502 penetrates the storage box 1 and is fixedly connected to the output shaft of the motor 501. The rotating rod 502 is provided with symmetrically distributed bidirectional thread grooves, and both ends of the bidirectional thread grooves are threadedly connected with sliding blocks 503 adapted thereto. The two sliding blocks 503 are rotatably connected with connecting shafts 504. The adjacent ends of the two connecting shafts 504 are rotatably connected with connecting blocks 505. The connecting block 505 is fixedly connected to an outer wall of one side of the low-temperature box 2. Through the above arrangement, when it is necessary to take out the stem cells, it can be achieved that only the motor 501 needs to be started. At this time, the output shaft of the motor 501 will drive The rotating rod 502 is rotated. When the rotating rod 502 rotates, the bidirectional threaded groove on the rotating rod 502 will drive the sliding block 503 matched therewith to move relatively. At this time, the two rotatably connected connecting shafts 504 will push the connecting block 505 to extend outward, and finally push the low-temperature box 2 to extend out of the storage box 1, so as to achieve the effect of exposing the stem cells in the storage box 1, which is convenient for users to take and place. This setting not only effectively solves the problem that the user needs to open the box door and put his hand into the box to take, but also the low-temperature box 2 for storing stem cells is more convenient for users to observe the storage status of the stem cells when it is fully exposed. The cross-installation of the storage box 1 and the low-temperature box 2 can, on the one hand, enhance the thermal insulation effect of the low temperature and reduce energy loss, and on the other hand, improve the sealing effect of the low-temperature box 2.

[0027] Furthermore, the pushing mechanism 5 also includes a limiting slide groove 506, which is opened on the inner wall of the storage box 1 and is adapted to one end of the sliding block 503. The sliding block 503 is limited and slidably connected in the limiting slide groove 506. Through this setting, the sliding block 503 can be further limited. Without affecting the reciprocating movement of the sliding block 503, the stability of the sliding block 503 during movement is improved, thereby improving the movement stability of the entire pushing mechanism 5.

[0028] Furthermore, the sealing mechanism 6 includes a piston strip 601 and an air storage chamber 602. The air storage chamber 602 is provided on a side of the low temperature box 2 away from the connecting block 505. The piston of the motor 501 is connected to the rotating rod 502. The inner wall of the storage box 1 is fixedly connected with a sealing plate 605. The sealing plate 605 passes through the low temperature box 2 and is located on the same horizontal line as the piston strip 601. A rectangular groove matching the contour of the low temperature box 2 is provided on the outer wall on the side away from the connecting block 505, and an elastic rectangular strip 603 is bonded in the rectangular groove. The air storage chamber 602 is connected to the rectangular groove. Through the above arrangement, it can be achieved that when the pushing mechanism 5 drives the low temperature box 2 to move During the retraction and resetting process, when the low-temperature box 2 is about to move to the end, the sealing plate 605 will abut against the piston bar 601 on the same horizontal line, and finally seal the top space of the stem cell storage bottle, improve the sealing, and push the piston bar 601 to squeeze into the air storage chamber 602. The generated compressed air can buffer the impact force when the low-temperature box 2 moves. At the same time, after the compressed air enters the rectangular groove, it will push the elastic rectangular bar 603 to expand, thereby increasing the abutment effect between the elastic rectangular bar 603 and the inner wall of the storage box 1, thereby achieving the effect of further enhancing the sealing between the storage box 1 and the low-temperature box 2.

[0029] Furthermore, the sealing mechanism 6 also includes a rectangular sealing groove 606, which is opened on the inner wall of the storage box 1 near the elastic rectangular strip 603 and is adapted to the elastic rectangular strip 603. Through this arrangement, the elastic rectangular strip 603 can be expanded under the compression of air and enter the adapted rectangular sealing groove 606, thereby forming a tighter waterproof sealing effect and enhancing the relative stability of the low-temperature box 2.

[0030] Furthermore, the sealing mechanism 6 also includes a plurality of spring wires 604, which are fixedly connected between the air storage chamber 602 and the piston bar 601. The moving distance of the piston bar 601 is less than the maximum deformation distance of the spring wire 604. Through this arrangement, when the piston bar 601 moves, the vibration of the force of the piston bar 601 can be reduced and buffered, and the resetting of the piston bar 601 can be facilitated.

[0031] Furthermore, shock-absorbing blocks 9 for shock absorption are installed at the four corners of the bottom of the storage box 1, and the top of the storage box 1 is fixedly connected with an elastic gripper 8 for easy grasping and two connecting rings 7 for easy connection of a shoulder strap. Through this arrangement, a shock-absorbing effect at the bottom of the lifting device can be achieved, and it is convenient for users to grasp or carry it on their backs for movement, thereby improving the practicability of the device.

[0032] Furthermore, a rectangular frame 4 is fixedly connected to the inner wall of the storage box 1, and the top of the rectangular frame 4 is fitted with an insulation board 3 for improving the sealing performance. The insulation board 3 is made of insulation material. Through this arrangement, the top of the stem cell storage bottle can be further sealed, the sealing performance of the device can be improved, and at the same time, the insulation effect of the device can be enhanced to reduce energy loss.

[0033] Working principle: When the device needs to take out the stem cells, it only needs to start the motor 501. At this time, the output shaft of the motor 501 will drive the rotating rod 502 to rotate. When the rotating rod 502 rotates, the bidirectional threaded groove on the rotating rod 502 will drive the sliding block 503 matched therewith to move relatively. At this time, the two rotating connecting shafts 504 will push the connecting block 505 to extend outward, and finally push the low-temperature box 2 to extend out of the storage box 1, so as to achieve the effect of exposing the stem cells in the storage box 1, which is convenient for users to take and place. This setting not only effectively solves the problem that the user needs to open the box door and put his hand into the box to take, but also makes it more convenient for users to observe the storage status of the stem cells when the low-temperature box 2 for storing stem cells is fully exposed. The cross-type installation of the storage box 1 and the low-temperature box 2 can enhance the low-temperature insulation effect and reduce energy loss on the one hand, and improve the sealing effect of the low-temperature box 2 on the other hand.

[0034] Through the above arrangement, it can be achieved that when the pushing mechanism 5 drives the low-temperature box 2 to retract and reset, when the low-temperature box 2 is about to move to the end, the sealing plate 605 will abut against the piston bar 601 on the same horizontal line, and finally seal the top space of the stem cell storage bottle, improve the sealing performance, and push the piston bar 601 to squeeze into the air storage chamber 602. The generated compressed air can, on the one hand, buffer the impact force when the low-temperature box 2 moves. At the same time, after the compressed air enters the rectangular groove, it will push the elastic rectangular bar 603 with elasticity to expand, thereby increasing the abutment effect between the elastic rectangular bar 603 and the inner wall of the storage box 1, thereby achieving the effect of further enhancing the sealing between the storage box 1 and the low-temperature box 2.

[0035] The above-mentioned specific embodiments are only several optional embodiments of the present invention. Based on the technical solution of the present invention and the relevant inspiration of the above-mentioned embodiments, those skilled in the art can make various alternative improvements and combinations to the above-mentioned specific embodiments.

Claims

1. A low temperature storage device for stem cells, characterized in that: The invention comprises a storage box (1) for storing stem cells, and further comprises: A low-temperature box (2) for creating a low-temperature environment is slidably connected inside the storage box (1); The storage box (1) is provided with a driving mechanism (5) for automatically controlling the movement of the low-temperature box (2); The low-temperature box (2) is provided with a sealing mechanism (6) for improving the sealing performance of the storage box (1) and the low-temperature box (2).

2. A stem cell cryopreservation device according to claim 1, characterized in that: The pushing mechanism (5) comprises a motor (501) and a rotating rod (502); the motor (501) is fixedly mounted on an outer wall of one side of the storage box (1); two ends of the rotating rod (502) are respectively rotatably connected to the inner wall of the storage box (1); one end of the rotating rod (502) passes through the storage box (1) and is fixedly connected to the output shaft of the motor (501); the rotating rod (502) is provided with symmetrically distributed bidirectional thread grooves, and both ends of the bidirectional thread grooves are threadedly connected to sliding blocks (503) adapted thereto; two sliding blocks (503) are rotatably connected to connecting shafts (504); adjacent ends of the two connecting shafts (504) are rotatably connected to connecting blocks (505); and the connecting block (505) is fixedly connected to an outer wall of one side of the low-temperature box (2).

3. A stem cell cryopreservation device according to claim 2, characterized in that: The pushing mechanism (5) further comprises a limiting slide groove (506), wherein the limiting slide groove (506) is formed on the inner wall of the storage box (1) and is adapted to fit one end of the sliding block (503), and the sliding block (503) is slidingly connected in the limiting slide groove (506).

4. A stem cell cryopreservation device according to claim 2, characterized in that: The sealing mechanism (6) comprises a piston strip (601) and an air storage chamber (602); the air storage chamber (602) is provided on a side of the low-temperature box (2) away from the connecting block (505); a piston of a plate body of the motor (501) is connected to the rotating rod (502); a sealing plate (605) is fixedly connected to the inner wall of the storage box (1); the sealing plate (605) passes through the low-temperature box (2) and is located on the same horizontal line as the piston strip (601); a rectangular groove matching the contour of the low-temperature box (2) is provided on the outer wall of the side away from the connecting block (505); an elastic rectangular strip (603) is bonded in the rectangular groove; and the air storage chamber (602) is connected to the rectangular groove.

5. A stem cell cryopreservation device according to claim 4, characterized in that: The sealing mechanism (6) further comprises a rectangular sealing groove (606), wherein the rectangular sealing groove (606) is formed on the inner wall of the storage box (1) close to the elastic rectangular strip (603) and is adapted to fit the elastic rectangular strip (603).

6. A stem cell cryopreservation device according to claim 4, characterized in that: The sealing mechanism (6) further comprises a plurality of spring wires (604), wherein the spring wires (604) are fixedly connected between the gas storage chamber (602) and the piston bar (601), and the moving distance of the piston bar (601) is smaller than the maximum deformation distance of the spring wires (604).

7. A stem cell cryopreservation device according to claim 1, characterized in that: Shock-absorbing blocks (9) for shock absorption are installed at the four corners of the bottom of the storage box (1), and an elastic gripper (8) for easy gripping and two connecting rings (7) for easy connection with a shoulder strap are fixedly connected to the top of the storage box (1).

8. The low-temperature storage device for stem cells according to claim 1, characterized in that: The inner wall of the storage box (1) is fixedly connected with a rectangular frame (4), and the top of the rectangular frame (4) is fittedly connected with a heat-insulating plate (3) for improving the sealing performance, wherein the heat-insulating plate (3) is made of a heat-insulating material.

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