Anti-settling and anti-caking reaction kettle for production of medical intermediates

Abstract

The utility model relates to the technical field of reaction kettle devices, in particular to an anti-settling and anti-caking reaction kettle for producing medical intermediates, which comprises a reaction kettle main body, a stirring mechanism and a conveying mechanism are arranged in the reaction kettle main body, and the stirring mechanism comprises a stirring sleeve rod, a scraper blade and a plurality of stirring blades. The stirring sleeve rod is rotatably arranged in the reaction kettle main body, the plurality of stirring blades are fixedly arranged outside the stirring sleeve rod, the lower end of the stirring sleeve rod is symmetrically provided with scraping plates, the positions, close to one side of the scraping plates, of the bottom of the stirring sleeve rod are symmetrically provided with feeding ports, and the upper part of the stirring sleeve rod is provided with a discharging port; the conveying mechanism is rotationally arranged in the stirring mechanism, the conveying mechanism comprises a rotating shaft and a spiral blade, and the spiral blade is fixedly arranged outside the rotating shaft. The conveying mechanism is matched with the stirring mechanism, materials at the bottom of the reaction kettle main body and scraped and caked materials sinking to the bottom are conveyed to the upper part and are circularly stirred by the stirring mechanism, so that the reaction is more sufficient, and the overall quality of a product is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of reaction kettle devices, in particular to an anti-settling and caking reaction kettle for producing pharmaceutical intermediates. Background Art

[0002] The preparation of pharmaceutical intermediates usually needs to consider many factors such as reaction conditions, catalyst selection, solvent use, purification methods, etc. In the pharmaceutical industry, the research and development of pharmaceutical intermediates also occupies an important position, because the efficient preparation and optimization of intermediates can directly affect the cost and efficiency of drug production. The production of pharmaceutical intermediates is usually prepared in a reactor.

[0003] At present, the mixing mode of the existing pharmaceutical intermediate production reactor is constantly being improved and optimized, which improves the overall quality of the pharmaceutical intermediate materials. However, in the actual production process, some materials at the bottom of the reactor sink to the bottom and agglomerate. These settled and agglomerated raw materials cannot move completely inside the reactor with the stirring mechanism, which will lead to incomplete internal reaction. In order to obtain higher quality pharmaceutical intermediate materials.

[0004] Therefore, a reaction kettle for preventing bottom settling and caking for producing pharmaceutical intermediates is proposed. Utility Model Content

[0005] The utility model aims to provide a reaction kettle for preventing bottom settling and caking for producing pharmaceutical intermediates, so as to solve the problem in the background technology that some materials have bottom settling and caking, resulting in incomplete reaction inside the reaction kettle.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a reactor for preventing bottom settling and caking for the production of pharmaceutical intermediates, comprising a reactor body, a stirring mechanism and a conveying mechanism arranged inside the reactor body, the stirring mechanism comprising a stirring sleeve, a scraper and a plurality of stirring blades, the stirring sleeve is rotatably arranged inside the reactor body, the plurality of stirring blades are fixedly arranged outside the stirring sleeve, the lower end of the stirring sleeve is symmetrically provided with a scraper, the bottom of the stirring sleeve is symmetrically provided with a feed port near one side of the scraper, the upper part of the stirring sleeve is provided with a discharge port, the conveying mechanism is rotatably arranged inside the stirring mechanism, the conveying mechanism comprises a rotating shaft and a spiral blade, and the spiral blade is fixedly arranged outside the rotating shaft;

[0007] The scraper is arranged at an angle, and the lower edge of the scraper is in contact with and separated from the inner bottom end of the reactor body. A baffle is arranged on the upper part of one side of the scraper. The upper part of the rotating shaft passes through the stirring sleeve rod and the first belt pulley. The rotating shaft is rotatably arranged inside the stirring sleeve rod and the first belt pulley. A second belt pulley is arranged on the upper end of the rotating shaft, and the second belt pulley is connected to the pulley through a second transmission belt.

[0008] Preferably, the spiral blade is arranged to spirally ascend in a clockwise direction, and the outer edge of the spiral blade is in contact with the inner wall of the stirring sleeve rod and is arranged separately.

[0009] Preferably, a first belt pulley is provided at the upper end of the stirring sleeve rod, the first belt pulley is connected to the belt pulley through a first transmission belt, and two groups of belt mounting grooves are provided on the outside of the belt pulley.

[0010] Preferably, the diameter of the first belt pulley is greater than the diameter of the second belt pulley, and the first belt pulley and the second belt pulley are arranged at the top of the reactor body.

[0011] Preferably, the pulley is arranged at the output end of the motor, the motor is arranged at the upper end of the mounting frame, and the mounting frame is fixedly arranged on the upper part of the reactor body.

[0012] Preferably, a valve-integrated feed port is provided at the upper end of the reactor body, an electric reactor lower ball valve is provided at the lower end of the reactor body, and a fixing frame is provided inside the reactor body, which is provided on the outside of the stirring sleeve and rotatably connected to the stirring sleeve.

[0013] Beneficial effects of the utility model:

[0014] 1. The utility model is designed with a stirring mechanism. When the stirring mechanism is in operation, the scraper at the bottom can scrape up the material that has settled to the bottom of the reactor body, effectively reducing the occurrence of incomplete reaction caused by material agglomeration at the bottom.

[0015] 2. The utility model designs a conveying mechanism, which cooperates with a stirring mechanism to convey the material at the bottom of the reactor body and the scraped and lumped material to the upper part, and circulates and stirs it through the stirring mechanism to make the reaction more complete and improve the overall quality of the product. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions in the present invention or the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings in the following description are only for the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 This is an overall stereogram of a reaction kettle for preventing bottom settling and caking for producing pharmaceutical intermediates according to an embodiment of the utility model;

[0018] Figure 2 The utility model is a reaction kettle for preventing the bottom from agglomeration in the production of pharmaceutical intermediates. Figure 1 Sectional view at AA;

[0019] Figure 3This is a partial three-dimensional schematic diagram of a reaction kettle for preventing bottom settling and caking for producing a pharmaceutical intermediate according to an embodiment of the utility model;

[0020] Figure 4 The utility model is a reaction kettle for preventing the bottom from agglomeration in the production of pharmaceutical intermediates. Figure 1 Cross-sectional view at BB in the middle.

[0021] The markings in the figure are: 1. Reactor body; 2. Valve integrated inlet; 3. Electric kettle low ball valve; 4. Fixed frame; 5. Stirring sleeve; 6. First belt pulley; 7. Feed inlet; 8. Discharge port; 9. Scraper; 10. Baffle; 11. Stirring blade; 12. Rotating shaft; 13. Spiral blade; 14. Second belt pulley; 15. Pulley; 16. First transmission belt; 17. Second transmission belt; 18. Mounting frame; 19. Motor. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with specific embodiments.

[0023] It should be noted that, unless otherwise defined, the technical terms or scientific terms used in the present invention should be understood by people with ordinary skills in the field to which the present invention belongs. The words "first", "second" and similar words used in the present invention do not indicate any order, quantity or importance, but are only used to distinguish different components. "Include" or "comprise" and similar words mean that the elements or objects appearing before the word include the elements or objects listed after the word and their equivalents, without excluding other elements or objects. "Connect" or "connected" and similar words are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "Up", "down", "left", "right" and the like are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0024] like Figures 1 to 4As shown, a specific embodiment of the utility model provides a reactor for preventing sedimentation and caking for the production of pharmaceutical intermediates, including a reactor body 1, wherein a stirring mechanism and a conveying mechanism are arranged inside the reactor body 1, wherein the stirring mechanism comprises a stirring sleeve 5, a scraper 9 and a plurality of stirring blades 11, wherein the stirring sleeve 5 is rotatably arranged inside the reactor body 1, wherein the plurality of stirring blades 11 are fixedly arranged outside the stirring sleeve 5, wherein the scraper 9 is symmetrically arranged at the lower end of the stirring sleeve 5, wherein a feed port 7 is symmetrically arranged at a position of the bottom of the stirring sleeve 5 near one side of the scraper 9, wherein a discharge port 8 is arranged at the upper part of the stirring sleeve 5, wherein the conveying mechanism is rotatably arranged inside the stirring mechanism, wherein the conveying mechanism comprises a rotating shaft 12 and a spiral blade 13, wherein the spiral blade 13 is fixedly arranged outside the rotating shaft 12.

[0025] By adopting the above technical scheme, the utility model is designed with a stirring mechanism, and the scraper 9 can scrape up the material that has settled and agglomerated at the bottom of the reactor body 1. The conveying mechanism cooperates with the stirring mechanism to transport the material at the bottom of the reactor body 1 and the scraped material to the upper part of the reactor body 1, and then the stirring blades 11 are used to stir the material inside the reactor body 1, so that the material inside the reactor body 1 is mixed more evenly, and the reaction inside the reactor body 1 is more sufficient, thereby avoiding the situation that the material at the bottom cannot be fully mixed and reacted due to sedimentation and agglomeration.

[0026] Specifically, Figure 2 and Figure 3 As shown, the scraper 9 is arranged obliquely, the lower edge of the scraper 9 is in contact with the inner bottom end of the reactor body 1 and is arranged separately, and a baffle 10 is arranged on the upper part of one side of the scraper 9.

[0027] By adopting the above technical solution, the scraper 9 is set at an angle. When the stirring mechanism stirs clockwise, the scraper 9 scrapes up the material at the bottom. The scraped material moves upward along one side of the scraper 9. In cooperation with the baffle 10, the material partially flows into the conveying mechanism under the obstruction of the baffle 10.

[0028] Specifically, Figure 2 As shown, the spiral blade 13 is arranged to spirally ascend in a clockwise direction, and the outer edge of the spiral blade 13 is in contact with the inner wall of the stirring sleeve rod 5 and is arranged separately.

[0029] By adopting the above technical solution, the spiral blade 13 is arranged to spirally rise in the clockwise direction, and can cooperate with the stirring mechanism to transport the material from the bottom of the device to the upper part of the device when stirring in the clockwise direction.

[0030] Specifically, Figure 2 and Figure 3 As shown, a first belt pulley 6 is provided at the upper end of the stirring sleeve rod 5 , and the first belt pulley 6 is connected to a pulley 15 through a first transmission belt 16 , and two groups of belt mounting grooves are provided outside the pulley 15 .

[0031] By adopting the above technical solution, the pulley 15 rotates through the first transmission belt 16 to rotate the first belt pulley 6, thereby realizing the rotation operation of the stirring mechanism. Two sets of belt mounting grooves are provided on the outside of the pulley 15, so that the stirring mechanism and the conveying mechanism can run simultaneously under the connection of the first transmission belt 16 and the second transmission belt 17.

[0032] Specifically, Figure 2 and Figure 3 As shown, the upper part of the rotating shaft 12 passes through the stirring sleeve rod 5 and the first belt pulley 6, and the rotating shaft 12 is rotatably arranged inside the stirring sleeve rod 5 and the first belt pulley 6. A second belt pulley 14 is arranged at the upper end of the rotating shaft 12, and the second belt pulley 14 is connected to the pulley 15 through a second transmission belt 17.

[0033] By adopting the above technical solution, the pulley 15 rotates through the second transmission belt 17 to rotate the second belt pulley 14, thereby realizing the operation of the conveying mechanism. The rotating shaft 12 passes through the stirring sleeve rod 5 and the first belt pulley 6 and is rotatably arranged inside the stirring sleeve rod 5 and the first belt pulley 6, so that the conveying mechanism can rotate and operate inside the stirring mechanism.

[0034] Specifically, Figure 2 As shown, the diameter of the first belt pulley 6 is greater than the diameter of the second belt pulley 14 , and the first belt pulley 6 and the second belt pulley 14 are arranged at the top end of the reactor body 1 .

[0035] By adopting the above technical solution, the diameter of the first belt pulley 6 is larger than the diameter of the second belt pulley 14. When the pulley 15 rotates, due to the small diameter of the second belt pulley 14, when the stirring mechanism and the conveying mechanism are running at the same time, the rotation speed of the conveying mechanism is greater than the speed of the stirring mechanism, thereby enabling the conveying mechanism to rotate inside the stirring mechanism and smoothly convey the material from the bottom to the upper part.

[0036] Specifically, Figure 1 and Figure 2 As shown, the pulley 15 is arranged at the output end of the motor 19 , the motor 19 is arranged at the upper end of the mounting frame 18 , and the mounting frame 18 is fixedly arranged on the upper part of the reactor body 1 .

[0037] By adopting the above technical solution, the pulley 15 is arranged at the output end of the motor 19, and the motor 19 is operated to drive the pulley 15 to rotate.

[0038] Specifically, Figure 1 and Figure 4 As shown, a valve-integrated feed port 2 is provided at the upper end of the reactor body 1, an electric reactor lower ball valve 3 is provided at the lower end of the reactor body 1, and a fixing frame 4 is provided inside the reactor body 1. The fixing frame 4 is arranged on the outside of the stirring sleeve rod 5 and is rotatably connected to the stirring sleeve rod 5.

[0039] By adopting the above technical solution, the reactor body 1 is provided with a valve-integrated feed port 2 and an electric reactor low ball valve 3, which are convenient for adding materials into the reactor body 1 and discharging the materials after the reaction is completed. A fixed frame 4 is provided inside the reactor body 1, and the fixed frame 4 is rotatably connected to the stirring sleeve rod 5, so as to reinforce the operation of the stirring mechanism inside the reactor body 1 and enhance the stability of the operation of the stirring mechanism.

[0040] Working principle: add the material into the reactor body 1, close the valve integrated feed port 2, and after the preparation work is completed, the staff starts the device, and the motor 19 drives the stirring mechanism and the conveying mechanism to run clockwise. The stirring mechanism stirs the material inside the reactor body 1 and scrapes up the material that is easy to agglomerate at the bottom of the reactor body 1. The material at the bottom of the reactor body 1 enters the conveying mechanism from the feed port 7, and the spiral blade 13 conveys the entered material to the upper part and discharges it from the discharge port 8. It is circulated and stirred by the stirring blade 11. After the material reaction process is completed, the motor 19 drives the stirring mechanism and the conveying mechanism to run counterclockwise, and the scraper 9 rotates to push the material at the bottom of the reactor body 1 to avoid accumulation and blockage during material discharge. At the same time, the conveying mechanism discharges the internal material. After the material inside the reactor body 1 is discharged, the production process is completed.

[0041] Those skilled in the art should understand that the discussion of any of the above embodiments is merely illustrative and is not intended to imply that the scope of the present invention (including the claims) is limited to these examples. Under the concept of the present invention, the technical features in the above embodiments or different embodiments may be combined, the steps may be implemented in any order, and there are many other variations of the different aspects of the present invention as described above, which are not provided in detail for the sake of simplicity.

[0042] The utility model is intended to cover all such substitutions, modifications and variations that fall within the broad scope of the appended claims. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the utility model should be included in the scope of protection of the utility model.

Claims

1. A reaction kettle for preventing sedimentation and caking for producing pharmaceutical intermediates, comprising a reaction kettle body (1), characterized in that: The reactor body (1) is provided with a stirring mechanism and a conveying mechanism inside; The stirring mechanism comprises a stirring sleeve rod (5), a scraper (9) and a plurality of stirring blades (11); the stirring sleeve rod (5) is rotatably arranged inside the reactor body (1); the plurality of stirring blades (11) are fixedly arranged outside the stirring sleeve rod (5); the scraper (9) is symmetrically arranged at the lower end of the stirring sleeve rod (5); a feed port (7) is symmetrically arranged at a position close to one side of the scraper (9) at the bottom of the stirring sleeve rod (5); a discharge port (8) is arranged at the upper part of the stirring sleeve rod (5); and the conveying mechanism is rotatably arranged inside the stirring mechanism; The conveying mechanism comprises a rotating shaft (12) and a spiral blade (13), wherein the spiral blade (13) is fixedly arranged outside the rotating shaft (12); The scraper (9) is arranged obliquely, and the lower edge of the scraper (9) is in contact with the inner bottom end of the reactor body (1) and is arranged separately. A baffle (10) is arranged on the upper part of one side of the scraper (9). The upper part of the rotating shaft (12) passes through the stirring sleeve rod (5) and the first belt pulley (6). The rotating shaft (12) is rotatably arranged inside the stirring sleeve rod (5) and the first belt pulley (6). A second belt pulley (14) is arranged on the upper end of the rotating shaft (12), and the second belt pulley (14) is connected to the pulley (15) through a second transmission belt (17).

2. The anti-settling and caking reaction kettle for producing pharmaceutical intermediates according to claim 1, characterized in that: The spiral blade (13) is arranged to spirally ascend in a clockwise direction, and the outer edge of the spiral blade (13) is in contact with the inner wall of the stirring sleeve rod (5) and is arranged separately.

3. The anti-settling and caking reaction kettle for producing pharmaceutical intermediates according to claim 1, characterized in that: A first belt pulley (6) is provided at the upper end of the stirring sleeve rod (5), and the first belt pulley (6) is connected to a pulley (15) via a first transmission belt (16), and two groups of belt mounting grooves are provided outside the pulley (15).

4. The anti-settling and caking reaction kettle for producing pharmaceutical intermediates according to claim 3, characterized in that: The diameter of the first belt pulley (6) is greater than the diameter of the second belt pulley (14), and the first belt pulley (6) and the second belt pulley (14) are arranged at the top end of the reactor body (1).

5. The anti-settling and caking reaction kettle for producing pharmaceutical intermediates according to claim 4, characterized in that: The pulley (15) is arranged at the output end of the motor (19), the motor (19) is arranged at the upper end of the mounting frame (18), and the mounting frame (18) is fixedly arranged on the upper part of the reaction kettle body (1).

6. The anti-settling and caking reaction kettle for producing pharmaceutical intermediates according to claim 1, characterized in that: The upper end of the reactor body (1) is provided with a valve-integrated material inlet (2), the lower end of the reactor body (1) is provided with an electric reactor lower ball valve (3), and the interior of the reactor body (1) is provided with a fixing frame (4), the fixing frame (4) is arranged on the outside of the stirring sleeve rod (5) and is rotatably connected to the stirring sleeve rod (5).

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