Organ-like culture pore plate support

Abstract

The utility model provides an organ-like culture pore plate bracket. The organ-like culture pore plate bracket comprises a bracket assembly and a supporting plate assembly, the support assembly comprises a base, an insertion cylinder and an insertion rod. The inserting cylinder is integrally formed on the upper side face of the base and located in the center of the base. A threaded hole is formed in the side part of the upper end of the insertion cylinder; bolts are mounted in the threaded holes; the lower end of the inserting rod is inserted from the upper end of the inserting cylinder; the end of the bolt abuts against the peripheral face of the lower end of the inserting rod, and therefore the inserting rod is fixed in the inserting cylinder. A ball joint seat is formed at the upper end of the insertion rod; a threaded part is formed on the inserting rod; the thread part is positioned at the downstream of the ball joint seat; a nut is mounted on the thread part; an annular inclined guide surface is formed at the lower part of the ball joint seat; a cutting groove is formed in the ball joint seat in the axial direction of the insertion rod; the supporting plate assembly comprises a supporting plate body; a concave organoid culture pore plate accommodating groove is formed in the upper side of the supporting plate body; a ball head is integrally formed on the lower side of the supporting plate body; the ball head of the supporting plate assembly is installed in the ball head joint seat of the support assembly.

Description

Technical Field

[0001] The present application relates to a medical experimental instrument, and in particular to an organoid culture well plate support. Background Art

[0002] Organoids are cultured in individual wells of a well plate (usually a 96-well plate). The organoid culture medium in the wells needs to be replaced regularly to provide the organoids with sufficient nutrient sources to maintain their continuous growth. When changing the medium, the original culture medium is first aspirated and discarded, and then the new culture medium is added. Each operation requires extreme caution to avoid damaging the organoids. During operation, the well plate is usually held in the left hand and tilted at an appropriate angle; the right hand uses a pipette to aspirate or add liquid. Due to the large number of wells, the liquid change process will take a relatively long time, and the left hand will be very sore and tired, which will also affect the precise operation of the right hand. Utility Model Content

[0003] In view of the above problems, the present application aims to propose an organoid culture well plate bracket, which can support the organoid culture well plate and free the operator's left hand.

[0004] The organoid culture well plate support of the present application comprises: a support assembly and a support plate assembly;

[0005] The bracket assembly comprises: a base, an insert tube, and an insert rod; the insert tube is integrally formed on the upper side of the base and is located at the center of the base; a threaded hole is opened on the side of the upper end of the insert tube; a bolt is installed in the threaded hole; the lower end of the insert rod is inserted from the upper end of the insert tube; the end of the bolt abuts against the outer peripheral surface of the lower end of the insert rod, thereby fixing the insert rod in the insert tube; a ball joint seat is formed at the upper end of the insert rod; a threaded portion is formed at the upper part of the insert rod; the threaded portion is located downstream of the ball joint seat; a nut is installed on the threaded portion; a ring-shaped inclined guide surface is formed at the lower part of the ball joint seat; a groove is formed on the ball joint seat along the axial direction of the insert rod;

[0006] The support plate assembly comprises a support plate body; the support plate body is formed with a concave organoid culture well plate receiving groove on its upper side; and the support plate body is integrally formed with a ball head on its lower side;

[0007] The ball head of the support plate assembly is installed in the ball head joint seat of the bracket assembly.

[0008] Preferably, a sliding ruler is installed on the support plate body.

[0009] Preferably, sliding grooves are formed laterally on the front and rear sides of the support plate body; downwardly extending supporting feet are formed at the front and rear ends of the sliding ruler, and a protrusion protruding toward the center of the support plate body is formed at the bottom end of each supporting foot; the protrusion can be slidably installed in the corresponding sliding groove.

[0010] Preferably, the sliding ruler is supported by the supporting feet and is at a predetermined height away from the upper side of the support plate body.

[0011] The organoid culture well plate holder of the present application can support the organoid culture well plate instead of the operator's left hand, and the inclination angle of the support plate body can be adjusted as needed. In this way, the operator frees his left hand and focuses all his attention on the right hand, so that he can operate the dropper more accurately. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 This is a schematic diagram of the three-dimensional structure of the organoid culture well plate support of the present application;

[0013] Figure 2 for Figure 1 A schematic diagram of the side view structure of the organoid culture well plate support;

[0014] Figure 3 for Figure 1 A schematic diagram of the three-dimensional structure of a support assembly of an organoid culture well plate support;

[0015] Figure 4 for Figure 3 A side structural schematic diagram of a bracket assembly;

[0016] Figure 5 for Figure 1 A schematic diagram of the three-dimensional structure of the support plate assembly of the organoid culture well plate support;

[0017] Figure 6 for Figure 5 A side structural schematic diagram of a support plate assembly. DETAILED DESCRIPTION

[0018] The organoid culture well plate support of the present application is described in detail below with reference to the accompanying drawings.

[0019] The organoid culture well plate support of the present application comprises: a support assembly and a support plate assembly.

[0020] The bracket assembly includes: a base 10 , an insert tube 11 , and an insert rod 12 .

[0021] The inserting tube 11 is integrally formed on the upper side of the base 10 and is located at the center of the base 10 .

[0022] A threaded hole is formed on the side of the upper end of the insert 11 , and a bolt 13 is installed in the threaded hole.

[0023] The lower end of the insertion rod 12 is inserted from the upper end of the insertion tube 11 ; the end of the bolt 13 abuts against the outer circumferential surface of the lower end of the insertion rod 12 , thereby fixing the insertion rod 12 in the insertion tube 11 .

[0024] A ball joint seat 15 is formed at the upper end of the insertion rod 12; a threaded portion is formed at the upper portion of the insertion rod 12; the threaded portion is located downstream of the ball joint seat 15; a nut 14 is installed on the threaded portion; a ring-shaped inclined guide surface 15a is formed at the lower portion of the ball joint seat 15; a groove 15b is formed on the ball joint seat 15 along the axial direction of the insertion rod 11.

[0025] The support plate assembly includes a support plate body 20 ; the support plate body 20 is formed with a concave organoid culture well plate receiving groove 21 on its upper side; the support plate body 10 is integrally formed with a ball head 24 on its lower side.

[0026] The ball head 24 of the support plate assembly is installed in the ball joint seat 15 of the bracket assembly to form a ball joint. The ball joint is a prior art and is used in some mobile phone holders. This application only applies it to the holder of this application. This application does not propose a new ball joint. When the ball joint moves upward through the nut 14, the groove 15b of the ball joint seat 15 is compressed and narrowed through the annular inclined guide surface 15a, thereby fixing the ball head 24 in the ball joint seat 15.

[0027] A sliding ruler 23 is mounted on the support plate body 20. The sliding ruler 23 is used to help the operator to replace the culture solution in the wells of the well plate along the longitudinal sequence or the transverse sequence.

[0028] The front and rear sides of the support plate body 20 are respectively formed with sliding grooves 22 transversely; the front and rear ends of the sliding ruler 23 are respectively formed with downwardly extending legs, and the bottom end of each leg is formed with a convex block protruding toward the center direction of the support plate body; the convex block can be slidably installed in the corresponding sliding groove 22. It is better to have a certain damping between the convex block and the sliding groove to facilitate the sliding ruler to be kept in a predetermined position.

[0029] The sliding ruler 23 is supported by the legs and is at a predetermined height away from the upper side of the support plate body 20 , so that the sliding ruler is at a predetermined height above the organoid culture well plate when sliding.

[0030] When in use, first loosen the ball joint seat through the nut, operate the support plate body to make it at an appropriate tilt angle, and then tighten the bolt to lock the ball head in the ball joint seat so that the support plate body remains in this tilted state. If necessary, the depth of the insertion of the rod into the insert can be adjusted by the bolt to adjust the height of the entire device. Place the organoid culture well plate into the organoid culture well plate receiving slot. Operate the sliding ruler to slide it to the side of a row or column of holes to be aspirated or dripped, and the operator can operate the dropper to operate along the row or column of holes indicated by the sliding ruler.

Claims

1. An organoid culture well plate support, characterized in that include: Bracket assembly, pallet assembly; The bracket assembly includes: a base, an insert tube, and an insert rod; The insert tube is integrally formed on the upper side of the base and is located at the center of the base; a threaded hole is opened on the side of the upper end of the insert tube; a bolt is installed in the threaded hole; the lower end of the insert rod is inserted from the upper end of the insert tube; the end of the bolt abuts against the outer peripheral surface of the lower end of the insert rod, thereby fixing the insert rod in the insert tube; a ball joint seat is formed at the upper end of the insert rod; a threaded portion is formed on the upper part of the insert rod; the threaded portion is located downstream of the ball joint seat; a nut is installed on the threaded portion; a ring-shaped inclined guide surface is formed at the lower part of the ball joint seat; a groove is formed on the ball joint seat along the axial direction of the insert rod; The support plate assembly comprises a support plate body; the support plate body is formed with a concave organoid culture well plate receiving groove on its upper side; and the support plate body is integrally formed with a ball head on its lower side; The ball head of the support plate assembly is installed in the ball head joint seat of the bracket assembly.

2. The organoid culture well plate support according to claim 1, characterized in that: A sliding ruler is installed on the support plate body.

3. The organoid culture well plate support according to claim 2, characterized in that: The front and rear sides of the support plate body are respectively formed with sliding grooves in the transverse direction; the front and rear ends of the sliding ruler are respectively formed with downwardly extending supporting feet, and the bottom end of each supporting foot is formed with a protrusion protruding toward the center direction of the support plate body; the protrusion can be slidably installed in the corresponding sliding groove.

4. The organoid culture well plate support according to claim 2, characterized in that: The sliding ruler is supported by the supporting legs and is at a predetermined height away from the upper side surface of the supporting plate body.

Images