Camera adjusting equipment and gene sequencer

Abstract

The utility model discloses camera adjusting equipment and a gene sequencer. Wherein the camera adjusting equipment comprises a camera mounting mechanism, a Z-direction adjusting mechanism, a Y-direction adjusting mechanism and an X-direction moving adjusting mechanism, the camera mounting mechanism comprises a first supporting frame and an X-direction rotating adjusting assembly, the X-direction rotating adjusting assembly comprises a holding ring and a rolling adjusting cylinder, and the rolling adjusting cylinder is provided with a camera mounting part; the Z-direction adjusting mechanism comprises a torsional pendulum adjusting frame, a Z-direction moving adjusting assembly and a Z-direction rotating adjusting assembly. The Y-direction adjusting mechanism comprises a first bearing plate, a second bearing plate, a third bearing plate, a Y-direction rotating adjusting assembly and a Y-direction moving adjusting assembly, and the second bearing plate has the degree of freedom of moving along the Y axis of the third bearing plate; the X-direction movement adjusting mechanism comprises a base plate and an X-direction movement adjusting assembly, and the third bearing plate has the movement freedom degree along the X axis of the base plate. The camera adjusting equipment disclosed by the utility model is compact in structure, and can realize independent, smooth, rapid and accurate adjustment of six degrees of freedom.

Description

Technical Field

[0001] The present disclosure relates to the technical field of gene sequencing detection, and in particular to a camera adjustment device and a gene sequencer. Background Art

[0002] During the development of the sequencing system, the assembly and adjustment of the optical machine is time-consuming. Since the imaging optical path in this field is relatively simple and there are no reflectors, the six degrees of freedom of the camera space need to be adjusted on the camera side, which makes the camera sensitive to the adjustment method and has high requirements.

[0003] The adjustment schemes disclosed in the prior art mainly have the following problems: 1) Unsmooth operation. For example, the slot-shaped sliding adjustment method disclosed in the prior art may encounter unsmoothness during adjustment, or even get stuck, which increases the difficulty and time-consuming of adjustment; 2) Insufficient space utilization. For example, the adjustment method using a split decoupling design disclosed in the prior art leads to insufficient space utilization and an insufficiently compact structure, which affects the optical and mechanical assembly; 3) Unstable adjustment. For example, some adjustment methods disclosed in the prior art use a spring adjustment pre-tightening method. Although there is a linear change during the adjustment process, in the presence of a vibration source, the rigidity of the imaging module is insufficient, causing image jitter; 4) The degrees of freedom of various parts of the device are coupled, resulting in a certain degree of coupling between the degrees of freedom when adjusting the position and angle of the camera. Adjusting one degree of freedom will affect the position or angle of other degrees of freedom, resulting in inaccurate, inflexible, and unsmooth adjustment. Users will feel resistance or unsmoothness when making fine adjustments, which not only increases the difficulty of operation, but also causes vibration or instability during the adjustment process, thereby affecting the imaging quality of the gene sequencer. Utility Model Content

[0004] In view of this, the embodiments of the present disclosure provide a camera adjustment device and a gene sequencer, which at least partially solve the problems existing in the prior art such as degree of freedom coupling, uneven adjustment, inaccurate adjustment, complex operation, and time-consuming operation.

[0005] In a first aspect, an embodiment of the present disclosure provides a camera adjustment device, including:

[0006] The camera mounting mechanism comprises a first support frame with a receiving hole, an X-axis rotation adjustment assembly mounted on the receiving hole, the X-axis rotation adjustment assembly comprises a tumbling adjustment cylinder and a matching holding ring, the tumbling adjustment cylinder has a camera mounting portion, and the tumbling adjustment cylinder has a degree of freedom to rotate around the X-axis direction;

[0007] The Z-direction adjustment mechanism comprises a sway adjustment frame with an assembly hole, a Z-direction movement adjustment component mounted on the sway adjustment frame, and a Z-direction rotation adjustment component mounted on one side of the sway adjustment frame, wherein the first support frame is mounted in the assembly hole, and the first support frame has the freedom to move along the Z-axis direction;

[0008] The Y-axis adjustment mechanism comprises a first carrier plate arranged at the bottom of the torsion adjustment frame, a second carrier plate arranged at the bottom of the first carrier plate, a third carrier plate arranged at the bottom of the second carrier plate, a Y-axis rotation adjustment component and a Y-axis movement adjustment component, wherein the Y-axis rotation adjustment component is installed on the first carrier plate and matched with the second carrier plate; the second carrier plate has the freedom to move along the Y-axis direction;

[0009] The X-direction movement adjustment mechanism comprises a base plate arranged at the bottom of the third carrying plate and an X-direction movement adjustment component installed on the base plate. The third carrying plate has the freedom to move along the X-axis direction.

[0010] Optionally, the Z-axis movement adjustment assembly includes an adjustment screw, a first adjustment member and a second adjustment member;

[0011] A first adjustment through hole is formed on the top of the torsion adjustment frame, one end of the adjustment screw passes through the first adjustment through hole and is fixedly connected to the first support frame, and the adjustment screw has the freedom to move along the central axis of the first adjustment through hole;

[0012] The two sides of the torsion adjustment frame are respectively provided with a first side adjustment hole and a second side adjustment hole, and the first adjustment member and the second adjustment member are respectively installed in the first side adjustment hole and the second side adjustment hole;

[0013] The first adjusting member and the second adjusting member are symmetrically arranged, and both the first adjusting member and the second adjusting member have the freedom to approach or move away from the first supporting frame.

[0014] Optionally, both sides of the first support frame have lugs, and each of the lugs has a through hole;

[0015] Both sides of the interior of the torsion adjustment frame are provided with grooves matching the lugs;

[0016] The torsion adjustment frame is provided with auxiliary adjustment holes and two groups of Z-direction guide holes;

[0017] The Z-direction movement adjustment assembly also includes an auxiliary adjustment member and two Z-direction guide posts, the two Z-direction guide posts are respectively matched with the two groups of Z-direction guide holes, and the two Z-direction guide posts respectively penetrate the two through holes; the two Z-direction guide posts are spaced apart from the two through holes;

[0018] The auxiliary adjustment member is installed in the auxiliary adjustment hole.

[0019] Optionally, a shaft step is provided at the bottom of the torsion and sway adjustment frame, and a central through hole matching the shaft step is opened on the first bearing plate;

[0020] Both sides of the bottom of the torsion adjustment frame are provided with engaging grooves, and the first bearing plate is provided with engaging bosses matching the gaps between the two engaging grooves;

[0021] One side of the torsion adjustment frame is provided with two rotation adjustment holes which are connected to the two engaging grooves;

[0022] The Z-direction rotation adjustment component comprises a first Z-direction rotation adjustment member and a second Z-direction rotation adjustment member, and the first Z-direction rotation adjustment member and the second Z-direction rotation adjustment member are respectively installed in the two rotation adjustment holes.

[0023] Optionally, the first adjusting member, the second adjusting member, the auxiliary adjusting member, the first Z-direction rotation adjusting member, and the second Z-direction rotation adjusting member are all top screws.

[0024] Optionally, the Y-axis rotation adjustment assembly includes a first group of Y-axis rotation adjustment members and a second group of Y-axis rotation adjustment members symmetrically arranged relative to the Y axis of the first carrier plate;

[0025] The first set of Y-axis rotation adjustment members includes two first adjustment screws symmetrically arranged relative to the X-axis of the first bearing plate;

[0026] The second set of Y-axis rotation adjusting members includes two second adjusting top screws symmetrically arranged relative to the X axis of the first bearing plate;

[0027] The two first adjusting top screws and the two second adjusting top screws all have a Z-direction freedom of movement, and the bottoms of the two first adjusting top screws and the two second adjusting top screws are tightly pressed against the top of the second bearing plate.

[0028] Optionally, a first Y-direction guide groove is provided at the bottom of the second carrying plate;

[0029] A second Y-direction guide groove matching the first Y-direction guide groove is formed on the top of the third carrying plate;

[0030] A Y-direction guide column is arranged between the first Y-direction guide groove and the second Y-direction guide groove.

[0031] Optionally, the Y-direction movement adjustment assembly includes two groups of Y-direction movement adjustment members symmetrically arranged relative to the X-axis of the third carrying plate;

[0032] The Y-axis movable adjustment member includes a bearing block, an adjusting screw sleeve and an adjusting screw rod, wherein the bearing block is provided with a guide through hole; the adjusting screw sleeve is fixedly arranged on the outer side of the bearing block and is communicated with the guide through hole; one end of the adjusting screw rod passes through the adjusting screw sleeve and protrudes out of the guide through hole, and the adjusting screw rod has the freedom to move longitudinally along the guide through hole.

[0033] Optionally, a first X-direction guide groove is provided at the bottom of the third carrying plate;

[0034] A second X-direction guide groove matching the first X-direction guide groove is formed on the top of the substrate;

[0035] An X-direction guide column is provided between the first X-direction guide groove and the second X-direction guide groove;

[0036] The X-direction movement adjustment component comprises two groups of X-direction movement adjustment members symmetrically arranged relative to the Y-axis of the substrate, and the X-direction movement adjustment members are arranged with the same structure as the Y-direction movement adjustment members.

[0037] In a second aspect, the embodiments of the present disclosure disclose a gene sequencer, which specifically includes a sequencer body, a camera, and the camera adjustment device described in any one of the above items;

[0038] The camera adjustment device is installed on the sequencer body;

[0039] The camera is mounted on the camera mounting portion;

[0040] The camera adjustment device also includes a fixing mechanism, which includes a first fixing component, a second fixing component, a third fixing component and a fourth fixing component. The first fixing component is used to fix the torsion adjustment frame to the first supporting plate after the adjustment is completed; the second fixing component is used to fix the first supporting plate to the second supporting plate after the adjustment is completed; the third fixing component is used to fix the second supporting plate to the third supporting plate after the adjustment is completed; and the fourth fixing component is used to fix the third supporting plate to the substrate after the adjustment is completed.

[0041] The camera adjustment device disclosed in the present application can realize the adjustment of the camera's movement in the X-axis, the Y-axis, the Z-axis, the rotation around the X-axis, the rotation around the Y-axis, or the rotation around the Z-axis, and realizes the smooth, fast, and flexible adjustment of the camera's six degrees of freedom. The adjustment difficulty is small, the adjustment accuracy is high, the adjustment cycle is short, and each degree of freedom can be adjusted separately, realizing the decoupling of the degrees of freedom. At the same time, the camera adjustment device disclosed in the present application has a reasonable design of the adjustment mechanism of each part, a compact structure, small space occupation, and simple operation. The user can easily adjust these mechanisms to achieve fine-tuning of the camera position and angle, without complicated operating steps, without moving the entire device or reinstalling it, which can effectively improve the convenience and efficiency of use.

[0042] The above description is only an overview of the technical solution of the present invention. In order to more clearly understand the technical means of the present invention, it can be implemented in accordance with the contents of the specification. In order to make the above and other purposes, features and advantages of the present invention more obvious and easy to understand, the following preferred embodiments are specifically cited and described in detail with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] In order to more clearly illustrate the technical solutions of the embodiments of the present disclosure, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present disclosure. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0044] Figure 1 A schematic diagram of the three-dimensional structure of a camera adjustment device provided in an embodiment of the present disclosure.

[0045] Figure 2 for Figure 1 Schematic diagram of the explosion.

[0046] Figure 3 for Figure 1 Schematic diagram of the structure of the torsion pendulum adjustment frame.

[0047] Figure 4 for Figure 1 Schematic diagram of the structure of the first supporting plate.

[0048] Figure 5 for Figure 1 Schematic diagram of some structures in .

[0049] Figure 6 Schematic diagram of the structure of the second group of Y-axis movable adjustment members in the embodiment of the present disclosure.

[0050] Description of reference numerals:

[0051] 10. Camera; 100. First support frame; 110. Lug; 200. X-axis rotation adjustment assembly; 210. Embracing ring; 220. Tumbling adjustment cylinder; 300. Swing adjustment frame; 310. Groove; 320. Axis step; 330. Engaging groove; 340. First side adjustment hole; 350. Second side adjustment hole; 400. Z-axis movement adjustment assembly; 410. Adjustment screw; 420. First adjustment member; 430. Second adjustment member; 440. Auxiliary adjustment member; 450. Z-axis guide hole; 500. Z-axis rotation adjustment assembly; 510. First Z-axis rotation adjustment member; 520. Second Z-axis rotation adjustment member; 600. First bearing plate; 610. Center through hole; 620. Engaging boss; 700. Second bearing plate; 710. First Y-axis guide groove; 800. Three bearing plates; 810, first X-direction guide groove; 820, Y-direction guide column; 900, Y-direction rotation adjustment assembly; 910, first group of Y-direction rotation adjustment parts; 920, second group of Y-direction rotation adjustment parts; 1000, Y-direction movement adjustment assembly; 1010, first group of Y-direction movement adjustment parts; 1020, second group of Y-direction movement adjustment parts; 1021, bearing block; 1022, adjustment screw sleeve; 1023, adjustment screw; 1100, base plate; 1110, second X-direction guide groove; 1120, X-direction guide column; 1200, X-direction movement adjustment assembly; 1210, first group of X-direction movement adjustment parts; 1220, second group of X-direction movement adjustment parts; 1310, first fixed assembly; 1320, second fixed assembly; 1330, third fixed assembly; 1340, fourth fixed assembly. DETAILED DESCRIPTION

[0052] The present disclosure is further described in detail below in conjunction with the accompanying drawings and implementations. It is understood that the specific implementations described herein are only used to explain the relevant content, rather than to limit the present disclosure. It should also be noted that, for ease of description, only the parts related to the present disclosure are shown in the accompanying drawings.

[0053] It should be noted that, in the absence of conflict, the embodiments and features of the embodiments in the present disclosure can be combined with each other. The technical solution of the present disclosure will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.

[0054] Unless otherwise specified, the exemplary embodiments / embodiments shown will be understood as providing exemplary features of various details of some ways in which the technical concept of the present disclosure can be implemented in practice. Therefore, unless otherwise specified, the features of the various embodiments / embodiments can be combined, separated, interchanged and / or rearranged without departing from the technical concept of the present disclosure.

[0055] The use of cross-hatching and / or shading in the accompanying drawings is generally used to make the boundaries between adjacent components clear. As such, unless otherwise specified, the presence or absence of cross-hatching or shading does not convey or indicate any preference or requirement for the specific materials, material properties, dimensions, proportions, commonalities between the components shown, and / or any other characteristics, attributes, properties, etc. of the components. In addition, in the accompanying drawings, the sizes and relative sizes of the components may be exaggerated for clarity and / or descriptive purposes. When the exemplary embodiments can be implemented differently, the specific process sequence can be performed in a different order than described. For example, two successively described processes can be performed substantially simultaneously or in an order opposite to the described order. In addition, the same figure numbers represent the same components.

[0056] When a component is referred to as being "on" or "over," "connected to," or "coupled to" another component, the component may be directly on, directly connected to, or directly coupled to the other component, or intervening components may be present. However, when a component is referred to as being "directly on," "directly connected to," or "directly coupled to" another component, there are no intervening components. For this purpose, the term "connected" may refer to a physical connection, an electrical connection, etc., with or without intervening components.

[0057] For descriptive purposes, the present disclosure may use spatially relative terms such as "under," "beneath," "under," "down," "over," "upper," "above," "higher," and "side (e.g., as in "sidewall")," to describe the relationship of one component to another (other) component as shown in the accompanying drawings. The spatially relative terms are intended to encompass different orientations of the device in use, operation, and / or manufacture in addition to the orientation depicted in the accompanying drawings. For example, if the device in the accompanying drawings is turned over, components described as "under" or "beneath" other components or features would subsequently be positioned "over" the other components or features. Thus, the exemplary term "under" can encompass both the "above" and "below" orientations. Furthermore, the device may be otherwise oriented (e.g., rotated 90 degrees or at other orientations), and the spatially relative descriptors used herein should be interpreted accordingly.

[0058] The terms used here are for the purpose of describing specific embodiments, and are not intended to be restrictive. As used here, unless the context clearly indicates otherwise, the singular forms "one (kind, person)" and "said (the)" are also intended to include plural forms. In addition, when the terms "comprise" and / or "include" and their variations are used in this specification, it is explained that there are stated features, integral bodies, steps, operations, parts, assemblies and / or their groups, but it is not excluded that there are or add one or more other features, integral bodies, steps, operations, parts, assemblies and / or their groups. It should also be noted that, as used here, the terms "substantially", "approximately" and other similar terms are used as approximate terms and not as degree terms, so that they are used to explain the inherent deviations of the measured values, calculated values ​​and / or the values ​​provided that will be recognized by those of ordinary skill in the art.

[0059] Reference Figure 1 and Figure 2 The first aspect of the present application discloses a camera adjustment device, including a camera mounting mechanism, a Z-axis adjustment mechanism, a Y-axis adjustment mechanism, and an X-axis movement adjustment mechanism, wherein the camera mounting mechanism includes a first support frame 100 and an X-axis rotation adjustment assembly 200, the first support frame 100 is provided with a receiving hole, and the X-axis rotation adjustment assembly 200 is installed in the receiving hole, that is, the X-axis rotation adjustment assembly 200 is supported by the first support frame 100; in this embodiment, the longitudinal center axis of the receiving hole is parallel to the X-axis of the space where the camera 10 is located. The X-axis rotation adjustment assembly 200 includes a holding ring 210 and a tumbling adjustment cylinder 220, the tumbling adjustment cylinder 220 has a camera mounting portion for mounting the camera 10, and the tumbling adjustment cylinder 220 has a degree of freedom to rotate around the longitudinal axis of the receiving hole, and the holding ring 210 and the tumbling adjustment cylinder 220 are matched. When it is necessary to adjust the rotation angle of the rolling adjustment cylinder 220 around the X-axis, the holding ring 210 loosens the rolling adjustment cylinder 220, and the rotation adjustment of the camera 10 is achieved by adjusting the rotation angle of the rolling adjustment cylinder 220. When the adjustment is completed, the holding ring 210 clamps the rolling adjustment cylinder 220 to fix the rolling adjustment cylinder 220 to the first support frame 100.

[0060] Furthermore, the first support frame 100 has an action portion matching the holding ring 210, and the action portion is arranged away from the camera 10, that is, in this embodiment, the camera mounting portion is located on the right side of the rolling adjustment cylinder 220, that is, the camera 10 is installed at the right end of the rolling adjustment cylinder 220, and the action portion is located on the left side of the first support frame 100. In the assembled state, one end (that is, the left end) of the rolling adjustment cylinder 220 is cantilevered after passing through the accommodating hole, and the holding ring 210 is sleeved on the outside of the action portion to clamp the action portion, thereby fixing the rolling adjustment cylinder 220.

[0061] The Z-axis adjustment mechanism includes a yaw adjustment frame 300, a Z-axis movement adjustment component 400 and a Z-axis rotation adjustment component 500. The yaw adjustment frame 300 is used to support the camera mounting mechanism, and the Z-axis movement adjustment component 400 is installed on the yaw adjustment frame 300, and is used to adjust the rise or fall of the first support frame 100 in the Z-axis direction, that is, to achieve the rise or fall adjustment of the camera 10 in the Z-axis direction.

[0062] The Z-axis rotation adjustment component 500 is installed on one side of the yaw adjustment frame 300, and is used to adjust the clockwise or counterclockwise rotation of the yaw adjustment frame 300 in the Z direction, that is, to achieve clockwise or counterclockwise adjustment of the camera 10 in the Z-axis direction; the Y-axis adjustment mechanism can adjust the movement of the camera 10 in the Y direction and the rotation around the Y axis; the X-axis movement adjustment mechanism can adjust the movement of the camera 10 in the X direction.

[0063] Furthermore, the yaw adjustment frame 300 is provided with an assembly hole, and the first support frame 100 is installed in the assembly hole, and the first support frame 100 has the freedom to move along the Z-axis of the yaw adjustment frame 300. The camera 10 is installed in the assembly hole with the first support frame 100, thereby ensuring a simple, compact structure and high stability.

[0064] In this embodiment, the assembly hole is preferably a central through hole, that is, the assembly hole is preferably located at the center of the yaw adjustment frame 300 .

[0065] The Y-axis adjustment mechanism includes a first carrier plate 600, a second carrier plate 700, a third carrier plate 800, a Y-axis rotation adjustment component 900 and a Y-axis movement adjustment component 1000. The torsion and sway adjustment frame 300 is installed on the top of the first carrier plate 600 and is matched with the first carrier plate 600. The matching setting here means that when the torsion and sway adjustment frame 300 is rotated around the Z axis through the Z-axis rotation adjustment component 500, it does not interfere with the first carrier plate 600.

[0066] The first supporting plate 600 is installed on the top of the second supporting plate 700 , and the first supporting plate 600 plays the role of supporting the torsion and sway adjustment frame 300 .

[0067] The Y-axis rotation adjustment component 900 is installed on the first carrier plate 600 and matched with the second carrier plate 700. The matching arrangement here means that when the Y-axis rotation adjustment component 900 is used to adjust the first carrier plate 600 around the Y axis, there is no interference with the second carrier plate 700.

[0068] The second supporting plate 700 is installed on the top of the third supporting plate 800 , and the second supporting plate 700 has the freedom to move along the Y-axis of the third supporting plate 800 .

[0069] The X-axis movement adjustment mechanism includes a base plate 1100 disposed at the bottom of the third carrier plate 800 and an X-axis movement adjustment assembly 1200 installed on the base plate 1100 . The third carrier plate 800 has the freedom to move along the X-axis of the base plate 1100 .

[0070] The Y-axis movement adjustment component 1000 is installed above the base plate 1100 , and the height of the action part of the Y-axis movement adjustment component 1000 matches the second carrier plate 700 , so as to facilitate the movement control of the second carrier plate 700 .

[0071] The camera adjustment device disclosed in the present application can realize the adjustment of the camera 10 in the X-axis movement, the Y-axis movement, the Z-axis movement, the rotation around the X-axis direction, the rotation around the Y-axis direction, or the rotation around the Z-axis direction, and realizes the smooth, fast, and flexible adjustment of the six degrees of freedom of the camera 10, with low adjustment difficulty, high adjustment accuracy, and short adjustment cycle, and each degree of freedom can be adjusted separately, realizing the decoupling of degrees of freedom. At the same time, the camera adjustment device disclosed in the present application has reasonable design of the adjustment mechanism of each part, compact structure, small space occupation, and simple operation. The user can easily adjust these mechanisms to achieve fine-tuning of the position and angle of the camera 10 without complicated operation steps, without moving the entire device or reinstalling it, which can effectively improve the convenience and efficiency of use.

[0072] Among them, the area of ​​the substrate 1100 is larger than the area of ​​the third supporting plate 800, the area of ​​the third supporting plate 800 is larger than the area of ​​the second supporting plate 700, and the area of ​​the second supporting plate 700 is larger than the area of ​​the first supporting plate 600, which can not only meet the six-degree-of-freedom adjustment of the camera 10, but also further improve the compactness and stability of the overall equipment.

[0073] In another embodiment, the Y-axis movement adjustment component 1000 may also be installed on the side of the third supporting plate 800 to achieve movement control of the second supporting plate 700 above it.

[0074] Furthermore, the camera adjustment device disclosed in the present application also includes a fixing mechanism for fixing corresponding components after the degrees of freedom of the camera 10 are adjusted by the device.

[0075] Specifically, the fixing mechanism includes a first fixing component 1310, a second fixing component 1320, a third fixing component 1330, and a fourth fixing component 1340. After completing the adjustment of the corresponding degrees of freedom, the first fixing component 1310 is used to fix the torsion adjustment frame 300 to the first supporting plate 600, the second fixing component 1320 is used to fix the first supporting plate 600 to the second supporting plate 700, the third fixing component 1330 is used to fix the second supporting plate 700 to the third supporting plate 800, and the fourth fixing component 1340 is used to fix the third supporting plate 800 to the substrate 1100.

[0076] Specifically, the first fixing assembly 1310 includes a plurality of first screws, and a plurality of mounting holes are provided on the yaw adjustment frame 300 and the first carrier plate 600; the free ends of the first screws pass downward through the mounting holes provided on the yaw adjustment frame 300 and are fixedly connected with the mounting holes provided on the first carrier plate 600, thereby fixing the yaw adjustment frame 300 and the first carrier plate 600. When the rotation angle of the camera 10 around the Z axis needs to be adjusted, the first fixing assembly 1310 is in a loosened state, which does not affect the rotation angle adjustment of the yaw adjustment frame 300 by the Z-direction rotation adjustment assembly 500, and when the rotation adjustment around the Z axis is completed, the first fixing assembly 1310 is tightened.

[0077] The second fixing assembly 1320 includes a plurality of second screws. The first bearing plate 600 and the second bearing plate 700 are provided with a plurality of mounting holes. The free ends of the second screws pass downward through the mounting holes provided on the first bearing plate 600 and are fixedly connected with the mounting holes provided on the second bearing plate 700, thereby fixing the first bearing plate 600 and the second bearing plate 700. When the rotation angle of the camera 10 around the Y axis needs to be adjusted, the second fixing assembly 1320 is in a loosened state, and the other fixing assemblies are in a tightened state, which does not affect the rotation angle adjustment of the first bearing plate 600 by the Y-axis rotation adjustment assembly 900. At this time, the first bearing plate 600, the yaw adjustment frame 300, the first support frame 100 and the camera 10 form a relatively fixed whole. Therefore, the rotation angle of the camera 10 is adjusted by adjusting the rotation angle of the first bearing plate 600. When the rotation adjustment around the Y axis is completed, the second fixing assembly 1320 is tightened.

[0078] The third fixing assembly 1330 includes a plurality of third screws. The second bearing plate 700 and the third bearing plate 800 are provided with a plurality of mounting holes. The free end of the third screw passes downward through the mounting hole provided on the second bearing plate 700 and is fixedly connected with the mounting hole provided on the third bearing plate 800, so as to fix the second bearing plate 700 and the third bearing plate 800. When it is necessary to adjust the moving position of the camera 10 along the Y axis, the third fixing assembly 1330 is in a loosened state, and the other fixing assemblies are in a tightened state, which does not affect the Y-direction moving adjustment assembly 1000 to adjust the movement of the second bearing plate 700 in the Y direction. At this time, the second bearing plate 700, the first bearing plate 600, the torsion adjustment frame 300, the first support frame 100 and the camera 10 form a relatively fixed whole. Therefore, the adjustment of the translation position of the camera 10 is achieved by adjusting the translation position of the second bearing plate 700. When the movement adjustment along the Y direction is completed, the third fixing assembly 1330 is tightened.

[0079] The fourth fixing assembly 1340 includes a plurality of fourth screws. The third carrier plate 800 and the base plate 1100 are provided with a plurality of mounting holes. The free end of the fourth screw passes downward through the mounting hole provided on the third carrier plate 800 and is fixedly connected with the mounting hole provided on the base plate 1100, so as to fix the third carrier plate 800 and the base plate 1100. When it is necessary to adjust the movement position of the camera 10 along the X axis, the fourth fixing assembly 1340 is in a loosened state, and the other fixing assemblies are in a tightened state, which does not affect the movement adjustment of the third carrier plate 800 in the X direction by the X-direction movement adjustment assembly 1200. At this time, the third carrier plate 800, the second carrier plate 700, the first carrier plate 600, the torsion adjustment frame 300, the first support frame 100 and the camera 10 form a relatively fixed whole. Therefore, the adjustment of the translation position of the camera 10 is achieved by adjusting the translation position of the third carrier plate 800. When the movement adjustment along the X direction is completed, the fourth fixing assembly 1340 is tightened.

[0080] Reference Figure 2 At the same time refer to Figure 3 The Z-axis movable adjustment component 400 includes an adjusting screw 410, a first adjusting member 420 and a second adjusting member 430; a first adjusting through hole is opened on the top of the torsion adjustment frame 300, one end of the adjusting screw 410 passes through the first adjusting through hole and is fixedly connected to the first support frame 100, and the adjusting screw 410 has the freedom of movement along the central axis of the first adjusting through hole.

[0081] A first side adjustment hole 340 and a second side adjustment hole 350 are respectively opened on both sides of the torsion adjustment frame 300, and the first adjustment member 420 and the second adjustment member 430 are respectively installed in the first side adjustment hole 340 and the second side adjustment hole 350; the first adjustment member 420 and the second adjustment member 430 are symmetrically arranged, and the first adjustment member 420 and the second adjustment member 430 both have the freedom to approach or move away from the first support frame 100.

[0082] When it is necessary to adjust the movement of the camera 10 in the Z-axis direction, first loosen the first adjusting member 420 and the second adjusting member 430, and then drive the first support frame 100 to rise or fall as a whole by adjusting the height of the adjusting screw 410. When it is adjusted to the target height, the first support frame 100 is clamped by the first adjusting member 420 and the second adjusting member 430 on both sides to complete the height fixation.

[0083] Furthermore, both sides of the first support frame 100 have lugs 110 , and each lug 110 has a through hole; both sides of the interior of the sway adjustment frame 300 have grooves 310 matching the lugs 110 .

[0084] An auxiliary adjustment hole and two groups of Z-direction guide holes 450 are provided on the torsion adjustment frame 300; the Z-direction movement adjustment assembly 400 also includes an auxiliary adjustment member 440 and two Z-direction guide columns, the two Z-direction guide columns are respectively matched with the two groups of Z-direction guide holes 450, and the two Z-direction guide columns respectively penetrate the two through holes; a gap is set between the two Z-direction guide columns and the two through holes to ensure that the positions of the two Z-direction guide columns are fixed; the auxiliary adjustment member 440 is installed in the auxiliary adjustment hole, and the end of the auxiliary adjustment member 440 is tightly pressed against the top of the first support frame 100.

[0085] During assembly, first fix the first support frame 100 and the sway adjustment frame 300 by means of the adjusting screw 410, the first adjusting member 420 and the second adjusting member 430, and then insert the two Z-direction guide columns from the top of the sway adjustment frame 300 downward through the two through holes and into the hole below the groove portion 310; when the height of the first support frame 100 is adjusted by means of the adjusting screw 410, the two Z-direction guide columns are used for Z-direction guidance to ensure precise adjustment; in addition, the auxiliary adjusting member 440 can be used to assist in regulating the descending height of the first support frame 100, which is simple and efficient.

[0086] The bottom of the torsion adjustment frame 300 is provided with an axis step 320, and the first bearing plate 600 is provided with a central through hole 610 matching the axis step 320. In this embodiment, the aperture of the central through hole 610 is larger than the outer diameter of the axis step 320 to ensure a gap between the two.

[0087] Both sides of the bottom of the torsion adjustment frame 300 are provided with locking grooves 330, and the first supporting plate 600 is provided with a locking boss 620 that matches the gap between the two locking grooves 330 to ensure that the locking boss 620 will not be stuck in the locking grooves 330, that is, the locking grooves 330 have a movement margin relative to the locking boss 620.

[0088] One side of the torsion adjustment frame 300 is provided with two rotation adjustment holes which are connected with the two engaging grooves 330; the Z-axis rotation adjustment assembly 500 includes a first Z-axis rotation adjustment member 510 and a second Z-axis rotation adjustment member 520, which are respectively installed in the two rotation adjustment holes.

[0089] In the assembled state, the ends of the first Z-axis rotation adjustment member 510 and the second Z-axis rotation adjustment member 520 are cantilevered after passing through the corresponding rotation adjustment holes, and the ends of the first Z-axis rotation adjustment member 510 and the second Z-axis rotation adjustment member 520 are tightly pressed against the sides of the corresponding locking bosses 620 to ensure the relative fixation of the torsion swing adjustment frame 300 and the first supporting plate 600.

[0090] When it is necessary to adjust the counterclockwise rotation angle of the sway adjustment frame 300 around the Z-axis, the first Z-axis rotation adjustment member 510 is adjusted to move inward, and the second Z-axis rotation adjustment member 520 is adjusted to move outward, that is, the end of the first Z-axis rotation adjustment member 510 extends longer in the engaging groove 330. Since the first supporting plate 600 where the engaging boss 620 is located is stationary at this time, it will exert a reverse thrust on the sway adjustment frame 300, thereby realizing the counterclockwise rotation of the sway adjustment frame 300 around the Z-axis. At this time, the outward movement of the second Z-axis rotation adjustment member 520 neither affects the counterclockwise rotation of the sway adjustment frame 300 nor limits the counterclockwise rotation of the sway adjustment frame 300.

[0091] Similarly, when it is necessary to adjust the clockwise rotation angle of the sway adjustment frame 300 around the Z-axis, the second Z-axis rotation adjustment member 520 is adjusted to move inward, and the first Z-axis rotation adjustment member 510 is adjusted to move outward, that is, the end of the second Z-axis rotation adjustment member 520 extends longer in the engaging groove 330. Since the first supporting plate 600 where the engaging boss 620 is located is stationary at this time, it will exert a reverse thrust on the sway adjustment frame 300, thereby realizing the clockwise rotation of the sway adjustment frame 300 around the Z-axis. At this time, the outward movement of the first Z-axis rotation adjustment member 510 neither affects the clockwise rotation of the sway adjustment frame 300 nor limits the clockwise rotation of the sway adjustment frame 300.

[0092] In this embodiment, the central through hole 610 is preferably opened at the center of the first supporting plate 600; the gap setting between the central through hole 610 and the shaft step 320 will not affect the rotation of the torsion and sway adjustment frame 300, and can ensure that the rotation center deviation of the torsion and sway adjustment frame 300 meets the requirements.

[0093] In this embodiment, the first adjusting member 420 , the second adjusting member 430 , the auxiliary adjusting member 440 , the first Z-direction rotation adjusting member 510 , and the second Z-direction rotation adjusting member 520 are preferably all top screws.

[0094] Reference Figure 2 At the same time refer to Figure 4 The Y-axis rotation adjustment assembly 900 includes a first group of Y-axis rotation adjustment members 910 and a second group of Y-axis rotation adjustment members 920, which are symmetrically arranged in the Y-axis direction relative to the first carrier plate 600, wherein the first group of Y-axis rotation adjustment members 910 includes two first adjustment top screws symmetrically arranged in the X-axis direction relative to the first carrier plate 600; the second group of Y-axis rotation adjustment members 920 includes two second adjustment top screws symmetrically arranged in the X-axis direction relative to the first carrier plate 600.

[0095] The two first adjusting top screws and the two second adjusting top screws both have Z-axis freedom of movement, and the bottoms of the two first adjusting top screws and the two second adjusting top screws are both pressed against the top of the second supporting plate 700, that is, the second supporting plate 700 is provided with holes matching the first adjusting top screws and the second adjusting top screws.

[0096] When it is necessary to adjust the counterclockwise rotation angle of the first carrier plate 600 around the Y-axis, the first group of Y-rotation adjusting members 910 are adjusted to move downward, and the second group of Y-rotation adjusting members 920 are adjusted to move upward, that is, the end of the first group of Y-rotation adjusting members 910 passes through the hole opened on the first carrier plate 600 and extends downward longer. Since the second carrier plate 700 is stationary at this time, it will exert a reverse thrust on the first carrier plate 600, thereby realizing the counterclockwise rotation of the first carrier plate 600 around the Y-axis. At this time, the upward movement of the second group of Y-rotation adjusting members 920 neither affects the counterclockwise rotation of the first carrier plate 600 nor limits the counterclockwise rotation of the first carrier plate 600.

[0097] Similarly, when it is necessary to adjust the clockwise rotation angle of the first carrier plate 600 around the Y-axis, the second group of Y-rotation adjusting members 920 are adjusted to move downward, and the first group of Y-rotation adjusting members 910 are adjusted to move upward, that is, the end of the second group of Y-rotation adjusting members 920 passes through the hole opened on the first carrier plate 600 and extends downward longer. Since the second carrier plate 700 is stationary at this time, it will exert a reverse thrust on the first carrier plate 600, thereby realizing the clockwise rotation of the first carrier plate 600 around the Y-axis. At this time, the upward movement of the first group of Y-rotation adjusting members 910 neither affects the clockwise rotation of the first carrier plate 600 nor limits the clockwise rotation of the first carrier plate 600.

[0098] Reference Figure 2 At the same time refer to Figure 5 A first Y-direction guide groove 710 is provided at the bottom of the second supporting plate 700, and the longitudinal axis of the first Y-direction guide groove 710 is parallel to the Y-axis; a second Y-direction guide groove matching the first Y-direction guide groove 710 is provided at the top of the third supporting plate 800; a Y-direction guide column 820 is arranged between the first Y-direction guide groove 710 and the second Y-direction guide groove.

[0099] In this embodiment, two first Y-direction guide grooves 710 are preferably provided, and the two first Y-direction guide grooves 710 are symmetrically arranged relative to the Y-direction central axis of the second supporting plate 700 .

[0100] Therefore, preferably, two second Y-direction guide grooves are provided, and preferably, two groups of Y-direction guide posts 820 are provided, which are placed corresponding to the two second Y-direction guide grooves respectively.

[0101] The Y-axis movable adjustment component 1000 includes two groups of Y-axis movable adjustment parts symmetrically arranged relative to the X-axis direction of the third supporting plate 800, namely a first group of Y-axis movable adjustment parts 1010 and a second group of Y-axis movable adjustment parts 1020; in the assembled state, the active ends of the two groups of Y-axis movable adjustment parts (i.e., the ends close to the second supporting plate 700) are respectively pressed against the two sides of the second supporting plate 700.

[0102] Further, refer to Figure 6 , taking the second group of Y-direction movable adjustment members 1020 as an example, the group of Y-direction movable adjustment members specifically includes a bearing block 1021, an adjusting screw sleeve 1022 and an adjusting screw 1023, and a guide through hole is opened on the bearing block 1021; the adjusting screw sleeve 1022 is fixedly arranged on the outer side of the bearing block 1021 and is connected with the guide through hole; one end of the adjusting screw 1023 passes through the adjusting screw sleeve 1022 and protrudes out of the guide through hole, and the adjusting screw 1023 has the freedom to move longitudinally along the guide through hole.

[0103] When it is necessary to adjust the second supporting plate 700 to move toward the first direction of the Y-axis, the adjusting screws in the first group of Y-direction movable adjusting members 1010 are adjusted to move inward (i.e., move toward the first direction), and the adjusting screws in the second group of Y-direction movable adjusting members 1020 are adjusted to move outward (i.e., move toward the first direction), thereby pushing the second supporting plate 700 to move toward the first direction of the Y-axis. At this time, the outward movement of the adjusting screws in the second group of Y-direction movable adjusting members 1020 neither affects the movement of the second supporting plate 700 nor limits the movement of the second supporting plate 700.

[0104] Similarly, when it is necessary to adjust the second supporting plate 700 to move in the second direction of the Y-axis (i.e., move in the opposite direction of the first direction of the Y-axis), the adjusting screws in the second group of Y-direction movable adjusting members 1020 are adjusted to move inward (i.e., move in the second direction), and the adjusting screws in the first group of Y-direction movable adjusting members 1010 are adjusted to move outward (i.e., move in the second direction), so as to push the second supporting plate 700 to move in the second direction of the Y-axis. At this time, the outward movement of the adjusting screws in the first group of Y-direction movable adjusting members 1010 neither affects the movement of the second supporting plate 700 nor limits the movement of the second supporting plate 700.

[0105] A first X-direction guide groove 810 is provided at the bottom of the third supporting plate 800, and the longitudinal axis of the first X-direction guide groove 810 is parallel to the X-axis; a second X-direction guide groove 1110 matching the first X-direction guide groove 810 is provided at the top of the base plate 1100; an X-direction guide column 1120 is arranged between the first X-direction guide groove 810 and the second X-direction guide groove 1110.

[0106] In this embodiment, two first X-direction guide grooves 810 are preferably provided, and the two first X-direction guide grooves 810 are symmetrically arranged relative to the X-direction central axis of the third supporting plate 800 .

[0107] Therefore, preferably, two second X-direction guide grooves 1110 are provided, and preferably, two groups of X-direction guide columns 1120 are provided, which are placed corresponding to the two second X-direction guide grooves 1110 respectively.

[0108] The X-axis movement adjustment assembly 1200 includes two groups of X-axis movement adjustment members symmetrically arranged relative to the Y-axis of the substrate 1100, namely a first group of X-axis movement adjustment members 1210 and a second group of X-axis movement adjustment members 1220; in the assembled state, the active ends of the first group of X-axis movement adjustment members 1210 and the second group of X-axis movement adjustment members 1220 (i.e., the ends close to the third supporting plate 800) are respectively pressed against the two sides of the third supporting plate 800.

[0109] In this embodiment, the first group of X-axis movable adjustment members 1210 and the second group of X-axis movable adjustment members 1220 have the same structure as the Y-axis movable adjustment members, except that the first group of X-axis movable adjustment members 1210 and the second group of X-axis movable adjustment members 1220 are preferably installed on two sides of the substrate 1100 to facilitate the movement control of the third supporting plate 800.

[0110] When it is necessary to adjust the third carrier plate 800 to move in the first direction of the X-axis, the adjusting screw 1023 in the first group of X-direction movable adjusting members 1210 is adjusted to move inward (i.e., move in the first direction), and the adjusting screw 1023 in the second group of X-direction movable adjusting members 1220 is adjusted to move outward (i.e., move in the first direction), so that the third carrier plate 800 can be pushed to move in the first direction of the X-axis. At this time, the outward movement of the adjusting screw 1023 in the second group of X-direction movable adjusting members 1220 neither affects the movement of the third carrier plate 800 nor limits the movement of the third carrier plate 800.

[0111] Similarly, when it is necessary to adjust the third carrier plate 800 to move in the second direction of the X-axis (i.e., move in the opposite direction of the first direction of the X-axis), the adjusting screw 1023 in the second group of X-direction movable adjusting members 1220 is adjusted to move inward (i.e., move in the second direction), and the adjusting screw 1023 in the first group of X-direction movable adjusting members 1210 is adjusted to move outward (i.e., move in the second direction), so that the third carrier plate 800 can be pushed to move in the second direction of the X-axis. At this time, the outward movement of the adjusting screw 1023 in the first group of X-direction movable adjusting members 1210 neither affects the movement of the third carrier plate 800 nor limits the movement of the third carrier plate 800.

[0112] In this embodiment, the guide setting of the corresponding guide column ensures that there is no jamming during the adjustment process, which facilitates quick installation and adjustment.

[0113] The second aspect of the present application discloses a gene sequencer, including a sequencer body, a camera, and the camera adjustment device, wherein the camera adjustment device is installed on the sequencer body, and the camera is installed on the camera mounting portion; through the camera adjustment device, high-precision control of the camera position can be achieved, that is, flexible control of the imaging optical path of the sequencing system can be achieved, ensuring that stable, true and consistent image information can be obtained through the gene sequencer to meet the high requirements of gene sequencing. It should be noted that the relevant descriptions of the camera adjustment device disclosed in the first aspect of the present application are all applicable to the camera adjustment device in the gene sequencer, and will not be repeated here.

[0114] In the description of this specification, the description with reference to the terms "one embodiment / method", "some embodiments / methods", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment / method or example are included in at least one embodiment / method or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment / method or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments / methods or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments / methods or examples described in this specification and the features of the different embodiments / methods or examples, unless they are contradictory.

[0115] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of this application, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0116] Those skilled in the art should understand that the above embodiments are only for the purpose of clearly illustrating the present disclosure, and are not intended to limit the scope of the present disclosure. For those skilled in the art, other changes or modifications may be made based on the above disclosure, and these changes or modifications are still within the scope of the present disclosure.

Claims

1. A camera adjustment device, characterized in that: include: The camera mounting mechanism comprises a first support frame with a receiving hole, an X-axis rotation adjustment assembly mounted on the receiving hole, the X-axis rotation adjustment assembly comprises a tumbling adjustment cylinder and a matching holding ring, the tumbling adjustment cylinder has a camera mounting portion, and the tumbling adjustment cylinder has a degree of freedom to rotate around the X-axis direction; The Z-direction adjustment mechanism comprises a sway adjustment frame with an assembly hole, a Z-direction movement adjustment component mounted on the sway adjustment frame, and a Z-direction rotation adjustment component mounted on the sway adjustment frame, wherein the first support frame is mounted in the assembly hole, and the first support frame has the freedom to move along the Z-axis direction; The Y-axis adjustment mechanism comprises a first carrier plate arranged at the bottom of the torsion adjustment frame, a second carrier plate arranged at the bottom of the first carrier plate, a third carrier plate arranged at the bottom of the second carrier plate, a Y-axis rotation adjustment component and a Y-axis movement adjustment component, wherein the Y-axis rotation adjustment component is mounted on the first carrier plate and matched with the second carrier plate; the second carrier plate has the freedom to move along the Y-axis direction; The X-direction movement adjustment mechanism comprises a base plate arranged at the bottom of the third carrying plate and an X-direction movement adjustment component installed on the base plate. The third carrying plate has the freedom to move along the X-axis direction.

2. The camera adjustment device according to claim 1, characterized in that: The Z-direction movement adjustment assembly includes an adjustment screw, a first adjustment member and a second adjustment member; A first adjustment through hole is formed on the top of the torsion adjustment frame, one end of the adjustment screw passes through the first adjustment through hole and is fixedly connected to the first support frame, and the adjustment screw has the freedom to move along the central axis of the first adjustment through hole; The two sides of the torsion adjustment frame are respectively provided with a first side adjustment hole and a second side adjustment hole, and the first adjustment member and the second adjustment member are respectively installed in the first side adjustment hole and the second side adjustment hole; The first adjusting member and the second adjusting member are symmetrically arranged, and both the first adjusting member and the second adjusting member have the freedom to approach or move away from the first supporting frame.

3. The camera adjustment device according to claim 2, characterized in that: Both sides of the first support frame have lugs, and each lug is provided with a through hole; Both sides of the interior of the torsion adjustment frame are provided with grooves matching the lugs; The torsion adjustment frame is provided with auxiliary adjustment holes and two groups of Z-direction guide holes; The Z-direction movement adjustment assembly also includes an auxiliary adjustment member and two Z-direction guide posts, the two Z-direction guide posts are respectively matched with the two groups of Z-direction guide holes, and the two Z-direction guide posts respectively penetrate the two through holes; the two Z-direction guide posts are spaced apart from the two through holes; The auxiliary adjustment member is installed in the auxiliary adjustment hole.

4. The camera adjustment device according to claim 3, characterized in that: The bottom of the torsion and sway adjustment frame is provided with an axis step, and the first bearing plate is provided with a central through hole matching the axis step; Both sides of the bottom of the torsion adjustment frame are provided with engaging grooves, and the first bearing plate is provided with engaging bosses matching the gaps between the two engaging grooves; One side of the torsion adjustment frame is provided with two rotation adjustment holes which are connected to the two engaging grooves; The Z-direction rotation adjustment component comprises a first Z-direction rotation adjustment member and a second Z-direction rotation adjustment member, and the first Z-direction rotation adjustment member and the second Z-direction rotation adjustment member are respectively installed in the two rotation adjustment holes.

5. The camera adjustment device according to claim 4, characterized in that: The first adjusting member, the second adjusting member, the auxiliary adjusting member, the first Z-direction rotating adjusting member, and the second Z-direction rotating adjusting member are all top screws.

6. The camera adjustment device according to claim 1, characterized in that: The Y-axis rotation adjustment assembly comprises a first group of Y-axis rotation adjustment members and a second group of Y-axis rotation adjustment members symmetrically arranged relative to the Y axis of the first carrier plate; The first set of Y-axis rotation adjustment members includes two first adjustment screws symmetrically arranged relative to the X-axis of the first bearing plate; The second set of Y-axis rotation adjusting members includes two second adjusting top screws symmetrically arranged relative to the X axis of the first bearing plate; The two first adjusting top screws and the two second adjusting top screws all have a Z-direction freedom of movement, and the bottoms of the two first adjusting top screws and the two second adjusting top screws are tightly pressed against the top of the second bearing plate.

7. The camera adjustment device according to claim 1, characterized in that: A first Y-direction guide groove is provided at the bottom of the second carrying plate; A second Y-direction guide groove matching the first Y-direction guide groove is formed on the top of the third carrying plate; A Y-direction guide column is arranged between the first Y-direction guide groove and the second Y-direction guide groove.

8. The camera adjustment device according to claim 7, characterized in that: The Y-direction movement adjustment assembly comprises two groups of Y-direction movement adjustment members symmetrically arranged relative to the X-axis of the third carrying plate; The Y-axis movable adjustment member includes a bearing block, an adjusting screw sleeve and an adjusting screw rod, wherein the bearing block is provided with a guide through hole; the adjusting screw sleeve is fixedly arranged on the outer side of the bearing block and is communicated with the guide through hole; one end of the adjusting screw rod passes through the adjusting screw sleeve and protrudes out of the guide through hole, and the adjusting screw rod has the freedom to move longitudinally along the guide through hole.

9. The camera adjustment device according to claim 8, characterized in that: A first X-direction guide groove is formed at the bottom of the third carrying plate; A second X-direction guide groove matching the first X-direction guide groove is formed on the top of the substrate; An X-direction guide column is provided between the first X-direction guide groove and the second X-direction guide groove; The X-direction movement adjustment component comprises two groups of X-direction movement adjustment members symmetrically arranged relative to the Y-axis of the substrate, and the X-direction movement adjustment members are arranged with the same structure as the Y-direction movement adjustment members.

10. A gene sequencer, characterized in that: It comprises a sequencer body, a camera and a camera adjustment device as described in any one of claims 1 to 9; The camera adjustment device is installed on the sequencer body; The camera is mounted on the camera mounting portion; The camera adjustment device also includes a fixing mechanism, which includes a first fixing component, a second fixing component, a third fixing component and a fourth fixing component. The first fixing component is used to fix the torsion adjustment frame to the first supporting plate after the adjustment is completed; the second fixing component is used to fix the first supporting plate to the second supporting plate after the adjustment is completed; the third fixing component is used to fix the second supporting plate to the third supporting plate after the adjustment is completed; and the fourth fixing component is used to fix the third supporting plate to the substrate after the adjustment is completed.

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