Kit for preparing NK cells

Abstract

The utility model discloses a kit for preparing NK (Natural Killer) cells, and relates to the technical field of immune cell culture. Through the arrangement of a self-adaptive clamping assembly, an operating mechanism and an adjustable mounting assembly, a flexible clamping plate can flexibly clamp a reagent tube under the elastic action of a first spring; the reagent tubes with different tube diameters can be adaptively clamped within the telescopic range of the first spring, so that the reagent tubes with different tube diameters can be conveniently and well stored; when the reagent tube needs to be taken out, only the operation mechanism needs to be used for pressing downwards, so that the flexible clamping plate loses the clamping effect with the reagent tube, or finally the flexible clamping plate is driven to be synchronously far away from the reagent tube and loses the flexible clamping effect on the reagent tube, and meanwhile, the other side of the adjustable mounting assembly jacks up the reagent tube, so that the reagent tube is conveniently taken out; therefore, reagent tubes with different tube diameters can be flexibly clamped by the kit in a self-adaptive manner, and meanwhile, the reagent tubes are more convenient to take and use.

Description

Technical Field

[0001] The utility model relates to the technical field of immune cell cultivation, and in particular to a kit for preparing NK cells. Background Art

[0002] Natural killer cells (NK) are the first line of defense of the body's natural immunity. They have highly effective anti-tumor, anti-viral infection and immune regulation functions, and play an important role in defending the body from diseases. Natural killer cells are not restricted by tissue compatibility antigens, that is, their killing activity is not restricted by MHC.

[0003] After searching, the patent document with publication number "CN207193296U" discloses a kit for preparing autologous NK cells, including a box body, a box cover, a base, a cell activator coating solution reagent tube, an NK cell stimulation solution reagent tube, an NK cell expansion basal medium reagent tube, an NK cell expansion medium reagent tube, and an autologous plasma reagent tube. The kit for preparing autologous NK cells of the utility model has a simple structure, is easy to use, has strong functional targeting, and is easy to be widely promoted and applied in the field of NK cell preparation.

[0004] Based on the above search and in combination with the prior art, it is found that the existing test kits for preparing NK cells mostly use a flexible clamping method to fix the various reagent tubes placed therein (such as the anti-slip rubber sleeve used in the above patent document). Although this fixing method can better fix the reagent tubes in the test kit, the diameters of the reagent tubes placed therein must be consistent, and it is difficult to completely unify the various reagent tubes when initially storing various reagents and nutrients (such as various reagents coming from different acquisition channels), and the existing test kits cannot be flexibly clamped according to reagent tubes of different diameters, which is inconvenient to use, and most of the existing test kits do not consider how to facilitate the removal of the reagent tubes. Therefore, a test kit for preparing NK cells is needed. Utility Model Content

[0005] The purpose of the present application is to provide a kit for preparing NK cells to solve the problems raised in the above-mentioned background technology.

[0006] To achieve the above-mentioned purpose, the present application provides the following technical solutions: a kit for preparing NK cells, comprising a box body and an empty reagent storage box, the upper end of the box body is provided with a box cover, the empty reagent storage box is fixed in the box body, a cavity is formed in the empty reagent storage box, and a reagent hole for storing a reagent tube is provided at the upper end of the empty reagent storage box;

[0007] A bottom bracket is fixed to the bottom wall of the cavity of the empty reagent storage box, an adjustable mounting assembly is installed on the upper end of the bottom bracket, an adaptive clamping assembly is installed on one side of the upper end of the adjustable mounting assembly, an operating mechanism is vertically installed through the empty reagent storage box, the upper part of the operating mechanism is slidably connected to the top of the empty reagent storage box, and when the operating mechanism is pressed downward, the adaptive clamping assembly is controlled to open outward and at the same time the other side of the adjustable mounting assembly lifts the reagent tube upward;

[0008] The adaptive clamping assembly includes a fixed plate, a slide bar and a flexible clamping plate. The lower end of the fixed plate is fixedly mounted on the adjustable mounting assembly. The slide bar slides horizontally through the fixed plate. One side of the flexible clamping plate is fixed to one end of the slide bar. A first spring is fixed to one side of the fixed plate close to the flexible clamping plate. The other end of the first spring is fixed to one side of the flexible clamping plate close to the fixed plate.

[0009] Among them, the inner wall cross-section of the side of the flexible clamping plate away from the fixed plate is an arc shape adapted to the reagent tube, and an arc chamfered portion is formed on the upper end of the flexible clamping plate.

[0010] Preferably, the base bracket corresponds to the position of the reagent hole, and an installation slide groove is provided at the upper end of the base bracket;

[0011] The adjustable mounting assembly includes a clamping base, a lifting block and a sliding block. Two sliding blocks are provided and are respectively fixed to the clamping base or the bottom surface of the lifting block. Both sliding blocks are slidably connected in the mounting slide groove.

[0012] The adjustable mounting assembly also includes a second spring, two second springs are provided, the two second springs are respectively fixed to the side walls on the opposite sides of the mounting slide groove, and the other ends of the two second springs are respectively fixed to the sides of the two sliders that are away from each other;

[0013] Among them, the two sliders slide along the installation groove to the side close to the bottom support axis and the side away from the bottom support axis respectively under the tendency of the operating mechanism, the lower end of the fixed plate is fixed to the upper end of the clamping base, and an arc-shaped inclined lifting wall is formed on the side of the lifting block away from the clamping base.

[0014] Preferably, a bracket for accommodating the bottom end of the reagent tube is provided in the middle of the base, a partition is formed in the installation groove, and two sliding blocks are respectively located on both sides of the partition.

[0015] Preferably, the operating mechanism includes a pressure rod and a driving pressure block, the pressure rod vertically slides through the top of the empty agent storage box, and the lower end of the pressure rod extends above the lifting block, the driving pressure block is fixed to the lower end of the pressure rod, a first chamfer is formed on one side of the lower end of the driving pressure block for movably abutting against a side of the clamping base close to the lifting block, and a second chamfer is formed on the other side of the lower end of the driving pressure block for movably abutting against a side of the lifting block close to the clamping base;

[0016] The upper ends of the clamping base and the lifting block are both formed with chamfered portions, the chamfered portion of the upper end of the clamping base is matched with the first chamfer, and the chamfered portion of the upper end of the lifting block is matched with the second chamfer.

[0017] Preferably, a through hole is opened in the middle of the pressure rod, and the sliding rod and the first spring both movably pass through the through hole.

[0018] Preferably, the adaptive clamping components are provided in multiple groups and distributed along the circumference of the upper end of the base, and the flexible clamping plates on the multiple groups of adaptive clamping components cooperate with each other to clamp the reagent tube;

[0019] The operating mechanism is also provided with multiple groups. The upper ends of the pressure rods in the multiple operating mechanisms are fixed together by a pressure ring. The pressure ring is a circular sheet structure. The pressure ring is located above the reagent hole and is arranged around the outside of the reagent hole. The inner diameter of the pressure ring is larger than the inner diameter of the reagent hole.

[0020] In summary, the technical effects and advantages of the utility model are:

[0021] 1. In the utility model, through the arrangement of the adaptive clamping assembly, the operating mechanism and the adjustable mounting assembly, when the reagent tube is inserted into the reagent hole of the empty reagent storage box, the lower end of the reagent tube first contacts the arc chamfered portion, and as the reagent tube is pressed downward, the flexible clamping plate slides outward and compresses the first spring, so that after the reagent tube enters the empty reagent storage box and the lower end abuts against the bottom support, the flexible clamping plate can flexibly clamp the reagent tube under the elastic action of the first spring, and can adaptively clamp reagent tubes of different diameters within the telescopic range of the first spring, thereby facilitating the better storage of reagent tubes of different diameters;

[0022] When the reagent tube needs to be taken out, it is only necessary to press down the operating mechanism and make one side of the adjustable mounting assembly move outward away from the axis of the base to drive the fixed plate to move outward, thereby resetting the first spring and stopping the elastic force applied to the flexible clamping plate, so that the flexible clamping plate loses the clamping effect on the reagent tube, or eventually drives the flexible clamping plate away from the reagent tube synchronously, losing the flexible clamping effect on the reagent tube, and at the same time, the other side of the adjustable mounting assembly lifts the reagent tube upward, thereby facilitating the removal of the reagent tube. In this way, while ensuring that the reagent test kit can adaptively and flexibly clamp reagent tubes of different diameters, it is also convenient to remove the reagent tubes stored in the reagent test kit, making it more convenient to use.

[0023] 2. In the present invention, the through hole is provided to avoid mutual interference between the movement of the pressure rod, the slide rod and the first spring, thereby ensuring smooth operation when depositing or taking out the reagent tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For those skilled in the art, other drawings can be obtained based on these drawings without paying any creative work.

[0025] Figure 1 Schematic diagram of the three-dimensional structure in this embodiment;

[0026] Figure 2 is a cross-sectional view of an empty agent storage box in this embodiment;

[0027] Figure 3 It is a schematic diagram of the three-dimensional structure of the adaptive clamping assembly, the base, the operating mechanism and the adjustable mounting assembly in this embodiment;

[0028] Figure 4 This is a schematic diagram of the structure of the adaptive clamping assembly and the adjustable mounting assembly when the bottom bracket is viewed in section in this embodiment;

[0029] Figure 5 In this embodiment Figure 4 A magnified view of the structure at center;

[0030] Figure 6 Schematic diagram of the operating mechanism and the pressure ring structure in this embodiment.

[0031] In the figure: 1. box body; 11. box cover; 2. empty reagent storage box; 21. reagent hole; 3. adaptive clamping assembly; 31. fixed plate; 32. slide bar; 33. flexible clamping plate; 331. arc chamfered portion; 34. first spring; 4. bottom support; 41. bracket; 42. mounting slide groove; 43. partition; 5. operating mechanism; 51. pressure rod; 511. through hole; 52. driving pressure block; 521. first chamfer; 522. second chamfer; 6. adjustable mounting assembly; 61. clamping base; 62. lifting block; 621. arc-shaped inclined lifting wall; 63. slider; 64. second spring; 7. pressure ring. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0033] Example: Reference Figure 1-6A kit for preparing NK cells shown in the figure comprises a box body 1 and an empty reagent storage box 2, wherein the upper end of the box body 1 is provided with a box cover 11, the empty reagent storage box 2 is fixed in the box body 1, a cavity is formed in the empty reagent storage box 2, and a reagent hole 21 for storing a reagent tube is opened at the upper end of the empty reagent storage box 2;

[0034] A bottom bracket 4 is fixed to the bottom wall of the cavity of the empty reagent storage box 2, an adjustable mounting assembly 6 is installed on the upper end of the bottom bracket 4, an adaptive clamping assembly 3 is installed on one side of the upper end of the adjustable mounting assembly 6, an operating mechanism 5 is vertically installed through the empty reagent storage box 2, the upper part of the operating mechanism 5 is slidably connected to the top of the empty reagent storage box 2, and when the operating mechanism 5 is pressed downward, the adaptive clamping assembly 3 is controlled to open outward and at the same time the other side of the adjustable mounting assembly 6 lifts the reagent tube upward;

[0035] The adaptive clamping assembly 3 includes a fixed plate 31, a slide bar 32 and a flexible clamping plate 33. The lower end of the fixed plate 31 is fixedly mounted on the adjustable mounting assembly 6. The slide bar 32 slides horizontally through the fixed plate 31. One side of the flexible clamping plate 33 is fixed to one end of the slide bar 32. A first spring 34 is fixed to one side of the fixed plate 31 close to the flexible clamping plate 33. The other end of the first spring 34 is fixed to one side of the flexible clamping plate 33 close to the fixed plate 31.

[0036] The inner wall cross-section of the side of the flexible clamping plate 33 away from the fixed plate 31 is an arc shape adapted to the reagent tube, and an arc chamfered portion 331 is formed at the upper end of the flexible clamping plate 33 .

[0037] Based on the above structure, when the reagent tube is inserted into the reagent hole 21 of the empty reagent storage box 2, the lower end of the reagent tube first contacts the arc chamfered portion 331, and as the reagent tube is pressed downward, the flexible clamping plate 33 slides outward and compresses the first spring 34, so that after the reagent tube enters the empty reagent storage box 2 and the lower end abuts against the bottom support 4, the flexible clamping plate 33 can flexibly clamp the reagent tube under the elastic action of the first spring 34, and can adaptively clamp reagent tubes of different diameters within the telescopic range of the first spring 34, thereby facilitating the better storage of reagent tubes of different diameters;

[0038] When the reagent tube needs to be taken out, it is only necessary to press down the operating mechanism 5 and make one side of the adjustable mounting assembly 6 move outward away from the axis of the base 4, so as to drive the fixed plate 31 to move outward, thereby resetting the first spring 34 and stopping the elastic force applied to the flexible clamping plate 33, so that the flexible clamping plate 33 loses the clamping effect on the reagent tube, or eventually drives the flexible clamping plate 33 away from the reagent tube synchronously, losing the flexible clamping effect on the reagent tube, and at the same time, the other side of the adjustable mounting assembly 6 pushes the reagent tube upward, so as to facilitate the removal of the reagent tube, thereby ensuring that the reagent test kit can perform adaptive flexible clamping on reagent tubes of different diameters, while facilitating the removal of the reagent tube stored in the reagent test kit, making it more convenient to use.

[0039] Furthermore, the base 4 corresponds to the position of the reagent hole 21, and a mounting slot 42 is provided at the upper end of the base 4;

[0040] The adjustable mounting assembly 6 includes a clamping base 61, a lifting block 62 and a slider 63. Two sliders 63 are provided and are respectively fixed to the bottom surface of the clamping base 61 or the lifting block 62. Both sliders 63 are slidably connected in the mounting slot 42.

[0041] The adjustable mounting assembly 6 further includes a second spring 64, two of which are provided. The two second springs 64 are respectively fixed to the side walls on opposite sides of the mounting slot 42, and the other ends of the two second springs 64 are respectively fixed to the sides of the two sliders 63 that are away from each other.

[0042] In order to ensure that the fixing plate 31 does not move when subjected to the elastic force applied by the first spring 34, the elastic force of the second spring 64 is greater than the elastic force of the first spring 34, and the second spring 64 is able to stably press against the slider 63 without external force, so that the slider 63 remains stable.

[0043] Among them, the two sliders 63 slide along the installation groove 42 to the side close to the axis of the base 4 and the side away from the axis of the base 4 under the tendency of the operating mechanism 5, the lower end of the fixed plate 31 is fixed to the upper end of the clamping base 61, and an arc-shaped inclined lifting wall 621 is formed on the side of the lifting block 62 away from the clamping base 61.

[0044] Furthermore, a bracket 41 for accommodating the bottom end of the reagent tube is opened in the middle of the base 4, a partition 43 is formed in the installation slide groove 42, and two sliders 63 are respectively located on both sides of the partition 43.

[0045] Furthermore, the operating mechanism 5 includes a pressure rod 51 and a driving pressure block 52. The pressure rod 51 vertically slides through the top wall of the empty agent storage box 2, and the lower end of the pressure rod 51 extends above the lifting block 62. The driving pressure block 52 is fixed to the lower end of the pressure rod 51. A first chamfer 521 is formed on one side of the lower end of the driving pressure block 52 to movably abut against a side of the clamping base 61 close to the lifting block 62, and a second chamfer 522 is formed on the other side of the lower end of the driving pressure block 52 to movably abut against a side of the lifting block 62 close to the clamping base 61.

[0046] Chamfered portions are formed on the upper ends of the clamping base 61 and the lifting block 62 . The chamfered portion on the upper end of the clamping base 61 matches the first chamfer 521 , and the chamfered portion on the upper end of the lifting block 62 matches the second chamfer 522 .

[0047] Through the setting of the operating mechanism 5 and the adjustable mounting assembly 6, when the reagent tube needs to be taken out, the user only needs to press down the pressure rod 51, so that the pressure rod 51 drives the driving pressure block 52 to descend synchronously, so that the first chamfer 521 of the driving pressure block 52 squeezes the clamping base 61 and makes the clamping base 61 move outward, and the second chamfer 522 of the driving pressure block 52 squeezes the lifting block 62 and makes the lifting block 62 move toward one side of the reagent tube, thereby driving the fixed plate 31 to move away from the reagent tube and finally making the flexible clamping plate 33 lose its flexible clamping effect on the reagent tube, and driving the lifting block 62 so that the arc-shaped inclined lifting wall 621 at one end of the lifting block 62 contacts the lower end of the reagent tube and gradually lifts the reagent tube, thereby facilitating the removal of the flexibly clamped reagent tube and achieving the effect of convenient access.

[0048] Furthermore, a through hole 511 is opened in the middle of the pressure rod 51, and the slide rod 32 and the first spring 34 are movable through the through hole 511. Through the setting of the through hole 511, the movement between the pressure rod 51, the slide rod 32 and the first spring 34 is prevented from interfering with each other, thereby ensuring smooth operation when depositing or removing the reagent tube.

[0049] Furthermore, the adaptive clamping assembly 3 is provided with multiple groups and distributed along the circumference of the upper end of the base 4, and the flexible clamping plates 33 on the multiple groups of adaptive clamping assemblies 3 cooperate with each other to clamp the reagent tube;

[0050] The operating mechanism 5 is also provided with multiple groups. The upper ends of the pressure rods 51 in the multiple groups of operating mechanisms 5 are fixed together by a pressure ring 7. The pressure ring 7 is a circular sheet structure. The pressure ring 7 is located above the reagent hole 21 and is arranged around the outside of the reagent hole 21. The inner diameter of the pressure ring 7 is larger than the inner diameter of the reagent hole 21. Through the setting of the pressure ring 7, multiple operating mechanisms 5 can be driven simultaneously, so as to better open multiple adaptive clamping components 3 at the same time, and drive multiple lifting blocks 62 at the same time to push the reagent tube upward, so that the process of removing the reagent tube is more stable.

[0051] Working principle of the utility model: in daily use, when the reagent tube is inserted into the reagent hole 21 of the empty reagent storage box 2, the lower end of the reagent tube first contacts the arc chamfered portion 331, and as the reagent tube is pressed downward, the flexible clamping plate 33 slides outward and compresses the first spring 34, so that after the reagent tube enters the empty reagent storage box 2 and the lower end abuts against the bottom support 4, the flexible clamping plate 33 can flexibly clamp the reagent tube under the elastic action of the first spring 34, and can adaptively clamp reagent tubes of different diameters within the telescopic range of the first spring 34, so as to facilitate the better storage of reagent tubes of different diameters;

[0052] When it is necessary to take out the reagent tube, it is only necessary to press the pressure ring 7 downward so that the pressure ring 7 drives the driving pressure block 52 to descend synchronously through the pressure rod 51, so that the first chamfer 521 of the driving pressure block 52 squeezes the clamping base 61 and makes the clamping base 61 move outward, and the second chamfer 522 of the driving pressure block 52 squeezes the lifting block 62 and makes the lifting block 62 move toward one side of the reagent tube, thereby driving the fixed plate 31 to move away from the reagent tube and finally making the flexible clamping plate 33 lose its flexible clamping effect on the reagent tube, and driving the lifting block 62 so that the arc-shaped inclined lifting wall 621 at one end of the lifting block 62 contacts the lower end of the reagent tube and gradually lifts the reagent tube, thereby facilitating the removal of the flexibly clamped reagent tube, while ensuring that the reagent test kit can adaptively and flexibly clamp reagent tubes of different diameters, it is convenient to take out the reagent tubes stored in the reagent test kit, and it is more convenient to use.

[0053] Finally, it should be noted that the above is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present utility model shall be included in the protection scope of the present utility model.

Claims

1. A kit for preparing NK cells, comprising a box body (1) and an empty reagent storage box (2), wherein the upper end of the box body (1) is provided with a box cover (11), the empty reagent storage box (2) is fixed in the box body (1), a cavity is formed in the empty reagent storage box (2), and the upper end of the empty reagent storage box (2) is provided with a reagent hole (21) for storing a reagent tube, characterized in that: A bottom bracket (4) is fixed to the bottom wall of the cavity of the empty reagent storage box (2), an adjustable mounting assembly (6) is mounted on the upper end of the bottom bracket (4), an adaptive clamping assembly (3) is mounted on one side of the upper end of the adjustable mounting assembly (6), an operating mechanism (5) is vertically penetrated and mounted on the empty reagent storage box (2), the upper part of the operating mechanism (5) is slidably connected to the top of the empty reagent storage box (2), and when the operating mechanism (5) is pressed downward, the adaptive clamping assembly (3) is controlled to open outward and at the same time the other side of the adjustable mounting assembly (6) lifts the reagent tube upward; The adaptive clamping assembly (3) comprises a fixed plate (31), a sliding rod (32) and a flexible clamping plate (33); the lower end of the fixed plate (31) is fixedly mounted on the adjustable mounting assembly (6); the sliding rod (32) slides horizontally through the fixed plate (31); one side of the flexible clamping plate (33) is fixed to one end of the sliding rod (32); a first spring (34) is fixed to a side of the fixed plate (31) close to the flexible clamping plate (33); the other end of the first spring (34) is fixed to a side of the flexible clamping plate (33) close to the fixed plate (31); The inner wall section of the side of the flexible clamping plate (33) away from the fixed plate (31) is in an arc shape adapted to the reagent tube, and an arc chamfered portion (331) is formed at the upper end of the flexible clamping plate (33); The base support (4) corresponds to the position of the reagent hole (21), and a mounting slide groove (42) is provided at the upper end of the base support (4); The adjustable mounting assembly (6) comprises a clamping base (61), a lifting block (62) and a sliding block (63), wherein two sliding blocks (63) are provided and are respectively fixed to the bottom surface of the clamping base (61) or the lifting block (62), and the two sliding blocks (63) are both slidably connected in the mounting slide groove (42); The adjustable mounting assembly (6) further comprises a second spring (64), wherein two second springs (64) are provided, and the two second springs (64) are respectively fixed to the side walls on opposite sides of the mounting slide groove (42), and the other ends of the two second springs (64) are respectively fixed to the sides of the two sliders (63) that are away from each other; The two slide blocks (63) slide along the mounting groove (42) respectively toward a side close to the axis of the base support (4) and a side away from the axis of the base support (4) under the influence of the operating mechanism (5); the lower end of the fixing plate (31) is fixed to the upper end of the clamping base (61); and an arc-shaped inclined lifting wall (621) is formed on a side of the lifting block (62) away from the clamping base (61); The operating mechanism (5) comprises a pressure rod (51) and a driving pressure block (52), wherein the pressure rod (51) vertically slides through the top of the empty agent storage box (2), and the lower end of the pressure rod (51) extends to above the lifting block (62), and the driving pressure block (52) is fixed to the lower end of the pressure rod (51), and a first chamfer (521) is formed on one side of the lower end of the driving pressure block (52) for movably abutting against a side of the clamping base (61) close to the lifting block (62), and a second chamfer (522) is formed on the other side of the lower end of the driving pressure block (52) for movably abutting against a side of the lifting block (62) close to the clamping base (61).

2. A kit for preparing NK cells according to claim 1, characterized in that: A bracket (41) for accommodating the bottom end of the reagent tube is provided in the middle of the base (4), a partition (43) is formed in the installation slide groove (42), and the two sliding blocks (63) are respectively located on both sides of the partition (43).

3. A kit for preparing NK cells according to claim 1, characterized in that: The upper ends of the clamping base (61) and the lifting block (62) are both formed with chamfered portions, the chamfered portion of the upper end of the clamping base (61) is adapted to the first chamfer (521), and the chamfered portion of the upper end of the lifting block (62) is adapted to the second chamfer (522).

4. A kit for preparing NK cells according to claim 3, characterized in that: A through hole (511) is provided in the middle of the pressure rod (51), and the sliding rod (32) and the first spring (34) both movably penetrate the through hole (511).

5. A kit for preparing NK cells according to claim 3, characterized in that: The adaptive clamping components (3) are provided in multiple groups and are distributed along the circumference of the upper end of the base (4), and the flexible clamping plates (33) on the multiple groups of the adaptive clamping components (3) cooperate with each other to clamp the reagent tube; The operating mechanism (5) is also provided with a plurality of groups, and the upper ends of the pressure rods (51) in the plurality of groups of the operating mechanism (5) are fixed together by a pressure ring (7), and the pressure ring (7) is a circular ring-shaped sheet structure. The pressure ring (7) is located above the reagent hole (21) and is arranged around the outside of the reagent hole (21), and the inner diameter of the pressure ring (7) is larger than the inner diameter of the reagent hole (21).

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