Sampling device for tumor pharmacological experiment
By designing a sampler for tumor pharmacology experiments including piston rod, straw and cutter spoon, the cumbersome problem of cleaning and disinfection in the prior art is solved, efficient multi-sample collection and tool integration are achieved, and operating efficiency and equipment life are improved.
Patent Information
- Application Number
- CN202420633084.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-29
- Publication Date
- 2024-12-27
- Estimated Expiration
- 2034-03-29
AI Technical Summary
The existing sampling device for tumor pharmacology experiments is complicated to disassemble parts during cleaning and disinfection, which reduces disinfection efficiency and increases the risk of component loss.
A device including a sampler and a sleeve is designed. The sampler has a built-in piston rod and a straw, combined with a cutter and a connecting ring, which can be used to collect liquid, powder and solid block samples, and can be fitted to reduce the volume after cleaning. Reduce tool replacement needs.
It realizes cleaning and disinfection operations without splitting parts, improves disinfection efficiency, reduces component losses, and reduces tool replacement times through multi-functional design.
Smart Images
Figure CN222258831U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical equipment, and specifically relates to a sampling device for tumor pharmacology experiments. Background Art
[0002] A tumor is a new organism formed when the cells of local tissues lose the normal regulation of their growth at the genetic level under the action of various tumorigenic factors, resulting in abnormal proliferation. This new organism often forms a local mass, hence the name. Biopsy of the tumor tissue is performed by various endoscopic biopsy forceps to obtain the tumor tissue; or surgical excision; or needle puncture and aspiration, etc., to conduct pharmacological experiments on the obtained tumor tissue, which can effectively study, analyze and observe the effects of anti-tumor therapeutic drugs, and has extremely important value in medical research. For example, the Chinese patent, authorization announcement number CN214073398U discloses a sampling device for tumor pharmacology experiments, which samples or reagents of different forms are sampled through mutually cooperating parts such as a needle tube, a telescopic tube, a fixed tube and a knife handle and a knife head. However, in the above-mentioned prior art, due to the large number of overlapping and telescopic structures, the various parts need to be disassembled and cleaned separately during the cleaning process after use, and the cleaning and disinfection process is relatively cumbersome, which reduces the efficiency of disinfection and increases the risk of component loss. Therefore, a sampling device for tumor pharmacology experiments is proposed. Utility Model Content
[0003] The purpose of the utility model is to provide a sampling device for tumor pharmacology experiments to solve the problems raised in the above background technology.
[0004] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a sampling device for tumor pharmacology experiments, comprising a sampler and a sleeve for accommodating the sampler, the sleeve being vertically fixed on a placement rack, the sampler being placed in the sleeve in a placement state, the sleeve providing a relatively closed dust-free environment for the sampler, the placement rack being used to fix the sleeve to prevent rolling or falling, the sampler comprising a cavity and a piston rod located in the cavity, the cooperation between the cavity and the piston rod being similar to the structure of a medical syringe, the piston head of the piston rod being interference-fitted with the inner surface of the cavity to achieve a sealed effect, the handle end of the piston rod extending from the upper port of the cavity to facilitate the staff to push and pull the piston rod, the cavity The lower port is sealed and connected with a straw, which is generally used to collect liquid samples in sampling operations. A connecting ring is sleeved on the outer surface of the cavity, and a connecting rod is arranged vertically downward on the connecting ring. A cutting spoon is fixedly connected to the lower end of the connecting rod. The cutting spoon is half-spoon-shaped and has a blade on the outer edge of the bottom of the spoon. When the staff performs sampling operations on powder samples, the connecting ring sleeved on the cavity is moved downward to make the cutting spoon lower than the end of the straw, and then the powder sample is directly scooped. When the staff performs sampling operations on solid block samples, the connecting ring sleeved on the cavity is moved downward to make the cutting spoon lower than the end of the straw, and then the outer edge of the bottom of the spoon is aligned with the solid block sample for cutting, and the cut solid block sample directly falls into the cutting spoon to complete the collection.
[0005] Preferably, an arc-shaped notch is provided at the bottom of the spoon at the intersection with the straw, and the diameter of the arc-shaped notch is larger than the outer diameter of the straw. After the staff completes the cleaning and disinfection of the sampler, the cutting spoon can be embedded with the straw through the arc-shaped notch, thereby reducing the volume space occupied by the lower end of the sampler, making it easier for the staff to store it into the sleeve.
[0006] Preferably, anti-slip patterns are provided on the upper surface of the spoon bottom. When the staff takes samples of powder samples or solid block samples, the anti-slip patterns on the upper surface of the spoon bottom increase the friction between the powder samples or solid block samples and the spoon bottom, thereby reducing the risk of falling.
[0007] Preferably, a thread is provided on the inner surface of the connecting ring and is threadedly connected to the outer surface of the upper end of the cavity. The staff can rotate the connecting ring through the thread, thereby realizing the up and down movement of the connecting ring on the outer surface of the cavity. The threaded connection makes it easy for the staff to more accurately control the up and down movement of the connecting ring on the outer surface of the cavity during operation, thereby further controlling the movement of the cutting spoon.
[0008] Preferably, a sleeve is provided on the outer surface of the connecting ring, and the upper end of the connecting rod is pin-connected with the sleeve. When the staff needs to engage the cutting spoon and the straw after finishing the cleaning and disinfection work, they only need to rotate the connecting rod to adjust the rotation direction of the cutting spoon, and the straw can be embedded in the notch of the cutting spoon at the lower end of the connecting rod.
[0009] Preferably, a convex ridge is provided axially on the outer surface of the lower end of the connecting rod. Since the connecting rod is generally a cylinder with a small diameter, when the worker's fingers pinch the connecting rod, the two are easy to slip. By providing the convex ridge, the friction between the fingers and the connecting rod can be increased, which can reduce repeated operations of the worker during the operation process.
[0010] Preferably, it is characterized in that: the lower end of the straw is a trumpet-shaped opening, and the inner diameter of the trumpet-shaped opening is larger than the outer diameter of the straw. When the staff occasionally encounters a solid block sample with a volume larger than the volume of the cutting spoon, the trumpet-shaped opening can be horizontally pressed against the solid block sample, and the piston rod can be pulled at the same time to generate negative pressure in the cavity and the straw, thereby grabbing and moving the solid block sample. Since the contact area between the trumpet-shaped opening and the solid block sample is increased, the degree of damage to the outer surface of the solid block sample during the grabbing process is reduced. This embodiment replaces traditional experimental tools such as tweezers and clamps, so that the staff can use the utility model to complete operations with various functional requirements without having to change tools.
[0011] Preferably, a strip groove is radially opened at the edge of the trumpet-shaped opening, and the strip groove opens downward. When the staff needs to sample the liquid sample, the trumpet-shaped opening at the lower end of the straw is placed flat on the bottom surface of the sample container, and the strip groove is placed in the liquid sample. At this time, the strip groove is the only entrance at the lower end of the straw. The staff pulls the piston rod to generate negative pressure in the cavity and the straw to absorb the liquid sample.
[0012] Preferably, a thread is provided on the inner surface of the upper end of the cavity, the piston rod is threadedly connected to the inner surface of the cavity, the handle end is hexagonal, and the hexagonal handle is convenient for the staff to rotate the piston rod. The threaded connection between the piston rod and the cavity also allows the staff to more accurately control the push and pull amplitude of the piston rod by rotation.
[0013] Preferably, a flange extends horizontally outward at the upper port of the cavity, and the structure of the flange can be used as a fulcrum for the staff's fingers to exert force during operation, which facilitates operation and prevents the staff's fingers from slipping. The flange is annular and a silicone sealing ring is attached to the lower surface. The inner diameter of the flange is smaller than the inner diameter of the sleeve, and the outer diameter of the flange is larger than the outer diameter of the sleeve. When the staff completes the cleaning and disinfection work, the sampler is placed in the sleeve, and the internal space of the sleeve can be further sealed by the flange and the sealing ring cooperating with the opening edge of the sleeve.
[0014] Compared with the prior art, the beneficial effects of the utility model are:
[0015] (1) Liquid samples, powder samples and solid block samples can be sampled by using the connecting ring, connecting rod and cutting spoon installed outside the cavity, and then using a straw. At the same time, since the relevant components are installed outside, they do not need to be disassembled during disinfection operations, which is convenient for staff to clean and organize.
[0016] (2) By providing an arc-shaped notch at the bottom of the cutting spoon, the cutting spoon can be engaged with the straw in a normal state, and the volume can be reduced when stored, thereby saving space.
[0017] (3) A trumpet-shaped opening with a strip groove is provided at the end of the straw, so that the staff can not only sample the liquid sample through the strip groove, but also take a larger volume of solid block sample through the trumpet-shaped opening without having to prepare a variety of tools. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 This is a schematic diagram of the overall appearance of the utility model;
[0019] Figure 2 This is a schematic diagram of the internal structure of the sampler of the utility model;
[0020] Figure 3 This is a top view of the handle end structure of the utility model;
[0021] Figure 4 This is a schematic diagram of the trumpet-shaped opening structure of the utility model;
[0022] Figure 5 It is a schematic diagram of the structure of a cutting spoon of the utility model.
[0023] In the figure: 1-placing rack, 2-sleeve, 3-cavity, 4-piston rod, 41-handle end, 5-straw, 51-trumpet-shaped opening, 52-strip groove, 6-connecting ring, 61-sleeve, 7-connecting rod, 8-cutting spoon, 81-spoon bottom, 82-arc-shaped notch. DETAILED DESCRIPTION
[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0025] Example:
[0026] See also Figure 1-5The utility model provides the following technical solutions: a sampling device for tumor pharmacology experiments, comprising a sampler and a sleeve 2 for accommodating the sampler, the sleeve 2 being vertically fixed on a placement rack 1, the sampler being placed in the sleeve 2 in the placement state, the sleeve 2 providing a relatively closed dust-free environment for the sampler, the placement rack 1 being used to fix the sleeve 2 to prevent rolling or falling, the sampler comprising a cavity 3 and a piston rod 4 located in the cavity 3, the cooperation between the cavity 3 and the piston rod 4 being similar to the structure of a medical syringe, the piston head of the piston rod 4 being interference-fitted with the inner surface of the cavity 3 to achieve a sealed effect, the handle end 41 of the piston rod 4 extending from the upper end of the cavity 3, facilitating the staff to push and pull the piston rod 4, the lower end of the cavity 3 A straw 5 is sealed and connected, and the straw 5 is generally used to collect liquid samples in sampling operations. A connecting ring 6 is sleeved on the outer surface of the cavity 3, and a connecting rod 7 is arranged vertically downward on the connecting ring 6. A cutting spoon 8 is fixedly connected to the lower end of the connecting rod 7. The cutting spoon 8 is half-spoon-shaped and has a blade on the outer side of the spoon bottom 81. When the staff performs a sampling operation on a powder sample, the connecting ring 6 sleeved on the cavity 3 is moved downward to make the cutting spoon 8 lower than the end of the straw 5, and then the powder sample is directly scooped. When the staff performs a sampling operation on a solid block sample, the connecting ring 6 sleeved on the cavity 3 is moved downward to make the cutting spoon 8 lower than the end of the straw 5, and then the outer side of the spoon bottom 81 is aligned with the solid block sample for cutting, and the cut solid block sample directly falls into the cutting spoon 8 to complete the collection.
[0027] Furthermore, the spoon bottom 81 is provided with an arc-shaped notch 82 at the intersection with the straw 5, and the diameter of the arc-shaped notch 82 is larger than the outer diameter of the straw 5. When the staff completes the cleaning and disinfection of the sampler, the cutting spoon 8 can be engaged with the straw 5 through the arc-shaped notch 82, thereby reducing the volume space occupied by the lower end of the sampler, making it easier for the staff to store it into the sleeve 2.
[0028] Furthermore, anti-slip patterns are provided on the upper surface of the spoon bottom 81. When the staff takes samples of powder samples or solid block samples, the anti-slip patterns on the upper surface of the spoon bottom 81 increase the friction between the powder samples or solid block samples and the spoon bottom 81, thereby reducing the risk of falling.
[0029] Furthermore, a thread is provided on the inner surface of the connecting ring 6 and is threadedly connected to the outer surface of the upper end of the cavity 3. The staff can rotate the connecting ring 6 through the thread, thereby realizing the up and down movement of the connecting ring 6 on the outer surface of the cavity 3. The threaded connection makes it easy for the staff to more precisely control the up and down movement of the connecting ring 6 on the outer surface of the cavity 3 during operation, thereby further controlling the movement of the cutting spoon 8.
[0030] Furthermore, a sleeve 61 is provided on the outer surface of the connecting ring 6, and the upper end of the connecting rod 7 is pin-connected with the sleeve 61. When the staff needs to engage the cutting spoon 8 and the straw 5 after finishing the cleaning and disinfection work, they only need to rotate the connecting rod 7 to adjust the rotation direction of the cutting spoon 8, so that the straw 5 can be embedded in the notch of the cutting spoon 8 at the lower end of the connecting rod 7.
[0031] Furthermore, a convex ridge is provided axially on the outer surface of the lower end of the connecting rod 7. Since the connecting rod 7 is generally a cylinder with a small diameter, when the worker's fingers pinch the connecting rod 7, the two are easy to slip. By providing the convex ridge, the friction between the fingers and the connecting rod 7 can be increased, which can reduce repeated operations of the worker during the operation process.
[0032] Furthermore, it is characterized in that: the lower end of the straw 5 is a trumpet-shaped opening 51, and the inner diameter of the trumpet-shaped opening 51 is larger than the outer diameter of the straw 5. When the staff occasionally encounters a solid block sample with a volume larger than the volume of the cutting spoon 8, the trumpet-shaped opening 51 can be horizontally pressed on the solid block sample, and the piston rod 4 can be pulled at the same time to generate negative pressure in the cavity 3 and the straw 5, so as to grab and move the solid block sample. Since the contact area of the trumpet-shaped opening 51 with the solid block sample is increased, the degree of damage to the outer surface of the solid block sample during the grabbing process is reduced. This embodiment replaces traditional experimental tools such as tweezers and clamps, so that the staff can use the utility model to complete operations with various functional requirements without having to change tools.
[0033] Furthermore, a strip groove 52 is radially opened at the edge of the trumpet-shaped opening 51, and the strip groove 52 opens downward. When the staff needs to sample the liquid sample, the trumpet-shaped opening 51 at the lower end of the straw 5 is placed flat on the bottom surface of the sample container, and the strip groove 52 is placed in the liquid sample. At this time, the strip groove 52 is the only entrance at the lower end of the straw 5. The staff pulls the piston rod 4 to generate negative pressure in the cavity 3 and the straw 5 to absorb the liquid sample.
[0034] Furthermore, a thread is provided on the inner surface of the upper end of the cavity 3, the piston rod 4 is threadedly connected to the inner surface of the cavity 3, the handle end 41 is hexagonal, and the hexagonal handle is convenient for the staff to rotate the piston rod 4. The threaded connection between the piston rod 4 and the cavity 3 also allows the staff to more accurately control the push and pull amplitude of the piston rod 4 by rotation.
[0035] Furthermore, a flange extends horizontally outward at the upper end of the cavity 3. The structure of the flange can be used as a fulcrum for the staff's fingers to exert force during operation, which facilitates operation while preventing the staff's fingers from slipping. The flange is annular and a silicone sealing ring is attached to the lower surface. The inner diameter of the flange is smaller than the inner diameter of the sleeve 2, and the outer diameter of the flange is larger than the outer diameter of the sleeve 2. When the staff completes the cleaning and disinfection work, the sampler is placed in the sleeve 2. The internal space of the sleeve 61 can be further sealed by the flange and the sealing ring cooperating with the opening edge of the sleeve 2.
[0036] Working principle: It includes a sampler and a sleeve 2 for accommodating the sampler, the sleeve 2 is vertically fixed on the placement rack 1, in the placement state, the sampler is placed in the sleeve 2, the sleeve 2 provides a relatively closed dust-free environment for the sampler, the placement rack 1 is used to fix the sleeve 2 to prevent rolling or falling, the sampler includes a cavity 3 and a piston rod 4 located in the cavity 3, the cooperation between the cavity 3 and the piston rod 4 is similar to the structure of a medical syringe, the piston head of the piston rod 4 and the inner surface of the cavity 3 are interference fit to achieve a sealed effect, the handle end 41 of the piston rod 4 extends from the upper end of the cavity 3, which is convenient for the staff to push and pull the piston rod 4, and the lower end of the cavity 3 is sealed and connected with a straw 5, the straw 5 is generally It is used to collect liquid samples during sampling operations. A connecting ring 6 is sleeved on the outer surface of the cavity 3. A connecting rod 7 is vertically downwardly arranged on the connecting ring 6. A cutting spoon 8 is fixedly connected to the lower end of the connecting rod 7. The cutting spoon 8 is half-spoon-shaped and is sharpened on the outer edge of the spoon bottom 81. When the staff performs sampling operations on powder samples, the connecting ring 6 sleeved on the cavity 3 is moved downward to make the cutting spoon 8 lower than the end of the straw 5, and then the powder sample is directly scooped. When the staff performs sampling operations on solid block samples, the connecting ring 6 sleeved on the cavity 3 is moved downward to make the cutting spoon 8 lower than the end of the straw 5, and then the outer edge of the spoon bottom 81 is aligned with the solid block sample for cutting. The cut solid block sample directly falls into the cutting spoon 8 to complete the collection.
[0037] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.
[0038] Finally, it should be noted that the above description is only a preferred embodiment of the utility model and is not intended to limit the utility model. Although the utility model is described in detail with reference to the above embodiments, those skilled in the art can still modify the technical solutions recorded in the above embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. within the spirit and principle of the utility model shall be included in the protection scope of the utility model.
Claims
1. A sampling device for tumor pharmacology experiments, comprising a sampler and a sleeve (2) for accommodating the sampler, wherein the sleeve (2) is vertically fixed on a placement frame (1), characterized in that: The sampler comprises a cavity (3) and a piston rod (4) located in the cavity (3); a handle end (41) of the piston rod (4) extends from an upper end of the cavity (3); a lower end of the cavity (3) is sealedly connected to a straw (5); a connecting ring (6) is sleeved on the outer surface of the cavity (3); a connecting rod (7) extending vertically downward is arranged on the connecting ring (6); a cutting spoon (8) is fixedly connected to the lower end of the connecting rod (7); the cutting spoon (8) is in the shape of a half spoon and has a blade on the outer side of the spoon bottom (81).
2. A sampling device for tumor pharmacology experiments according to claim 1, characterized in that: The spoon bottom (81) is provided with an arc-shaped notch (82) at the intersection with the straw (5), and the diameter of the arc-shaped notch (82) is larger than the outer diameter of the straw (5).
3. A sampling device for tumor pharmacology experiments according to claim 2, characterized in that: Anti-slip patterns are arranged on the upper surface of the spoon bottom (81).
4. A sampling device for tumor pharmacology experiments according to claim 1, characterized in that: The inner surface of the connecting ring (6) is provided with threads and is threadedly connected to the outer surface of the upper end of the cavity (3).
5. A sampling device for tumor pharmacology experiments according to claim 4, characterized in that: A sleeve (61) is arranged on the outer surface of the connecting ring (6), and the upper end of the connecting rod (7) is pin-connected to the sleeve (61).
6. A sampling device for tumor pharmacology experiments according to claim 5, characterized in that: A convex ridge is arranged along the axial direction on the outer surface of the lower end of the connecting rod (7).
7. A sampling device for tumor pharmacology experiments according to any one of claims 1 to 6, characterized in that: The lower end of the straw (5) is a trumpet-shaped opening (51), and the inner diameter of the trumpet-shaped opening (51) is greater than the outer diameter of the straw (5).
8. A sampling device for tumor pharmacology experiments according to claim 7, characterized in that: A strip groove (52) is radially provided at the edge of the trumpet-shaped opening (51), and the strip groove (52) opens downward.
9. A sampling device for tumor pharmacology experiments according to claim 1, characterized in that: The inner surface of the upper end of the cavity (3) is provided with a thread, the piston rod (4) is connected to the inner surface of the cavity (3) by a thread, and the handle end (41) is hexagonal.
10. The sampling device for tumor pharmacology experiments according to claim 1, characterized in that: A flange extends horizontally outward at the upper end of the cavity (3); the flange is annular and has a silicone sealing ring attached to the lower surface; the inner diameter of the flange is smaller than the inner diameter of the sleeve (2), and the outer diameter of the flange is larger than the outer diameter of the sleeve (2).