Spray needle cleaning device of liquid chromatograph-mass spectrometer
Through the combination of ultrasonic cleaning tank and booster pump, the problem of solid impurities residue inside the needle of the liquid-mass combo instrument is solved, and effective internal cleaning and recycling of the cleaning liquid is achieved, which improves the cleaning efficiency and sensitivity of the needle .
Patent Information
- Application Number
- CN202420204306.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-01-29
- Publication Date
- 2024-12-31
- Estimated Expiration
- 2034-01-29
AI Technical Summary
The existing liquid-mass combo needle cleaning device is difficult to completely remove solid impurities inside the needle, especially the cleaning effect of the inner wall of the needle tube is poor.
The ultrasonic cleaning tank is combined with the booster pump and the sponge sleeve. The circulating cleaning liquid driven by the booster pump enters the inside of the needle to ensure that the cleaning liquid can penetrate effectively and rinse the inside. It is sealed with the support cover and sealed silicone gasket. and fixed.
Effectively clean the residual impurities inside the spray needle, and the cleaning liquid can be recycled, improving the cleaning efficiency and sensitivity of the spray needle.
Smart Images
Figure CN222268106U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of liquid-mass spectrometers, in particular to a needle cleaning device of a liquid-mass spectrometer. Background Art
[0002] If the spray needle of the LC-MS instrument is exposed to the mobile phase of the salt solution for a long time, irregular spray will be produced, affecting the sensitivity. Therefore, the spray needle of the LC-MS instrument needs to be fully cleaned to avoid the residual compound impurities collected last time on the spray needle, which will affect the sensitivity when sampling the spray needle.
[0003] Chinese patent CN218424490U discloses a needle cleaning device for a liquid-mass spectrometer, comprising: a box body, the top of which is an opening, and a cover plate is provided at the opening; a partition box, the partition box is fixedly connected to the bottom of the cover plate, and a plurality of vertically arranged rotating shafts are rotatably connected in the partition box, and one end of the rotating shaft that passes through the outside of the partition box is detachably connected to a placement plate, and the placement plates are all arranged horizontally, and a through hole is provided on the top of the placement plate for placing the vertically arranged needles; a motor, the motor is fixedly installed in the partition box, and the motor is used to drive the rotation of the rotation shaft. The utility model can limit the ring to the rotating shaft through the setting of the plug rod, spring and slot, so that the placement plate is stably and firmly fixed under the rotating shaft, so that when the motor is working, the placement plate is driven to rotate through the rotating shaft, so that the needle on the placement plate is rotated and cleaned in the cleaning liquid in the box.
[0004] However, the above technical solution still has the following defects: although the outer wall of the spray needle can be cleaned well, there may still be residues on the inner wall of the needle tube, especially when there are solid impurities remaining, which is difficult to completely clean by the impact of external water flow alone. Utility Model Content
[0005] The technical problem to be solved by the utility model is to provide a spray needle cleaning device for a liquid-mass spectrometer, which can effectively clean the residual impurities inside the spray needle, and the cleaning liquid can be recycled.
[0006] In order to solve the above technical problems, the utility model adopts the following technical solutions:
[0007] A needle cleaning device for a liquid-mass spectrometer comprises an ultrasonic cleaning pool, wherein an inner cleaning pool is provided inside the ultrasonic cleaning pool, a support cover is provided at the pool mouth of the inner cleaning pool, a needle is fixedly inserted on the support cover, and a connecting pipe is provided between the inner cleaning pool and the ultrasonic cleaning pool; a support frame is provided inside the ultrasonic cleaning pool, a movable buckle is provided on the support frame, the inner cleaning pool and the support cover are detachably mounted on the support frame via the movable buckle, and a buckle groove is provided on the support cover corresponding to the movable buckle; a booster pump is provided on the connecting pipe.
[0008] Furthermore, the pool opening of the cleaning inner pool is provided with an annular slot, and the support cover is mounted in the slot.
[0009] Furthermore, the support cover is provided with an annular block corresponding to the slot, the outer edge of the support cover extends outward beyond the pool opening of the inner cleaning pool, and the support cover is in an outwardly protruding arc shape.
[0010] Furthermore, the card block is externally wrapped with a sealing silicone pad.
[0011] Furthermore, a plurality of insertion holes are evenly spaced apart on the support cover, a sponge sleeve is laid in the insertion hole, and the spray needle is inserted in the sponge sleeve.
[0012] Beneficial effects of the utility model:
[0013] In actual use scenarios, the cleaning liquid is loaded into the ultrasonic cleaning pool, the spray needle to be cleaned is fixed to the support cover, the cleaning inner pool is placed on the support frame in the ultrasonic cleaning pool, the connecting pipe with the booster pump installed is placed in the cleaning liquid, and the support cover is closed to the pool mouth of the cleaning inner pool, and the cleaning inner pool and the support cover are fixed with a movable buckle, and the ultrasonic cleaning pool is started for ultrasonic cleaning. At the same time, the connecting pipe is opened so that the cleaning liquid can enter the cleaning inner pool to soak the spray needle. After cleaning for 3-4 minutes, the booster pump is started to squeeze the cleaning liquid in the ultrasonic cleaning pool into the cleaning inner pool, so that the cleaning liquid can enter the inside of the spray needle and flow back from the top, and flow back to the ultrasonic cleaning pool along the support cover to form a cycle. The utility model can effectively clean the residual impurities inside the spray needle, and the cleaning liquid can be recycled. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 It is a schematic diagram of the overall cross-sectional structure of the utility model;
[0015] Figure 2 For the utility model Figure 1 A is an enlarged structural diagram;
[0016] Figure 3 It is a schematic diagram of the top view of the support cover of the utility model. DETAILED DESCRIPTION
[0017] In order to facilitate the understanding of those skilled in the art, the present invention is further described below in conjunction with embodiments and drawings. The contents mentioned in the implementation modes are not intended to limit the present invention.
[0018] like Figure 1-3As shown, the utility model provides a needle cleaning device for a liquid-mass spectrometer, comprising an ultrasonic cleaning pool 1, wherein an inner cleaning pool 2 is provided inside the ultrasonic cleaning pool 1, a support cover 3 is provided at the pool mouth of the inner cleaning pool 2, a spray needle is fixedly inserted on the support cover 3, a connecting pipe 4 is provided between the inner cleaning pool 2 and the ultrasonic cleaning pool 1; a support frame 11 is provided inside the ultrasonic cleaning pool 1, a movable buckle 12 is provided on the support frame 11, the inner cleaning pool 2 and the support cover 3 are detachably mounted on the support frame 11 through the movable buckle 12, a buckle groove 31 is provided on the support cover 3 corresponding to the movable buckle 12; a booster pump 41 is provided on the connecting pipe 4.
[0019] In this embodiment, the cleaning liquid is loaded into the ultrasonic cleaning pool 1, the spray needle to be cleaned is fixed to the support cover 3, the cleaning inner pool 2 is placed on the support frame 11 in the ultrasonic cleaning pool 1, the connecting pipe 4 with the booster pump 41 installed is placed in the cleaning liquid, and then the support cover 3 is closed to the pool mouth of the cleaning inner pool 2, and then the cleaning inner pool 2 and the support cover 3 are fixed by the movable buckle, and the ultrasonic cleaning pool 1 is started for ultrasonic cleaning, and the connecting pipe 4 is opened at the same time so that the cleaning liquid can enter the cleaning inner pool to soak the spray needle. After cleaning for 3-4 minutes, the booster pump is started to squeeze the cleaning liquid in the ultrasonic cleaning pool 1 into the cleaning inner pool 2, so that the cleaning liquid can enter the inside of the spray needle and flow back from the top, and flow back to the ultrasonic cleaning pool 1 along the support cover 11 to form a cycle. The cleaning device can effectively clean the residual impurities inside the spray needle, and the cleaning liquid can be recycled.
[0020] like Figure 2 As shown, the pool opening of the cleaning inner pool 2 is provided with an annular slot 21, and the support cover 3 is clamped in the slot 21; in this embodiment, the slot 21 is provided to facilitate the fixation and clamping of the support cover 3 to prevent displacement.
[0021] like Figure 2 As shown, the support cover 3 is provided with an annular block 32 corresponding to the card slot 21, and the outer edge of the support cover 3 extends outward beyond the pool opening of the inner cleaning pool 2, and the support cover 3 is in an outward arc shape; in this embodiment, the outer edge of the support cover 3 extends outward beyond the pool opening of the inner cleaning pool 2, and the support cover 3 is in an outward arc shape, which is convenient for the reflux of the cleaning liquid.
[0022] like Figure 2 As shown, the block 32 is wrapped with a sealing silicone pad on the outside; in this embodiment, the sealing silicone pad is used to form a sealed space between the support cover 3 and the cleaning inner pool 2, so that when the booster pump 41 is pressurized, the cleaning liquid can smoothly enter the needle tube of the spray needle and thoroughly clean the inside.
[0023] like Figure 3As shown, the support cover 3 is provided with a plurality of insertion holes 33 at even intervals, a sponge cover 34 is provided in the insertion hole 33, and the spray needle is inserted in the sponge cover 34; in this embodiment, the sponge cover 34 can not only fix and clamp the spray needle, but also protect the spray needle from damage.
[0024] All technical features in this embodiment can be modified in appearance according to actual needs.
[0025] The above embodiments are preferred implementation schemes of the present invention. In addition, the present invention can also be implemented in other ways. Any obvious replacement without departing from the concept of the present technical solution is within the protection scope of the present invention.
Claims
1. A needle cleaning device for a liquid chromatography-mass spectrometer, characterized in that: The ultrasonic cleaning pool (1) comprises an inner cleaning pool (2) provided inside the ultrasonic cleaning pool (1), a support cover (3) being provided at the pool opening of the inner cleaning pool (2), a spray needle being fixedly inserted on the support cover (3), and a connecting pipe (4) being provided between the inner cleaning pool (2) and the ultrasonic cleaning pool (1); The ultrasonic cleaning pool (1) is provided with a support frame (11), the support frame (11) is provided with a movable buckle (12), the cleaning inner pool (2) and the support cover (3) are detachably mounted on the support frame (11) via the movable buckle (12), and the support cover (3) is provided with a buckle groove (31) corresponding to the movable buckle (12); The connecting pipe (4) is provided with a booster pump (41).
2. The needle cleaning device for a liquid chromatography-mass spectrometer according to claim 1, characterized in that: The pool opening of the inner cleaning pool (2) is provided with an annular clamping groove (21), and the support cover (3) is clamped in the clamping groove (21).
3. The needle cleaning device for a liquid chromatography-mass spectrometer according to claim 2, characterized in that: The support cover (3) is provided with an annular clamping block (32) corresponding to the clamping groove (21); the outer edge of the support cover (3) extends outward beyond the pool opening of the inner cleaning pool (2); and the support cover (3) is in an outwardly protruding arc shape.
4. The needle cleaning device for a liquid chromatography-mass spectrometer according to claim 3, characterized in that: The card block (32) is externally wrapped with a sealing silicone pad.
5. The needle cleaning device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The support cover (3) is provided with a plurality of insertion holes (33) at even intervals, a sponge sleeve (34) is arranged in the insertion hole (33), and the spray needle is inserted in the sponge sleeve (34).