Bone tissue engineering scaffold fractal structure
By designing the fractal structure of bone tissue engineering stents, including limiting chutes and disassembly sockets, the problem that existing stents cannot be flexibly adjusted is solved, and flexible splicing and disassembly of the stent length is achieved, which improves the flexibility and efficiency of treatment.
Patent Information
- Application Number
- CN202420738436.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-10
- Publication Date
- 2025-01-03
- Estimated Expiration
- 2034-04-10
AI Technical Summary
The existing bone tissue engineering stent lacks the function of splitting and splicing, and it is impossible to flexibly select the appropriate stent length according to the patient's bone defect site for bone regeneration treatment.
A fractal structure of bone tissue engineering stent is designed, including fractal stent body, top plate, bottom plate, limit chute and disassembly socket. Through the use of limit slide and slide chute, the flexible splicing and separation of the bracket is achieved. Medical personnel are allowed to adjust the length of the stent according to the length of the patient's bone damage.
The flexible splicing and splitting of the stent is achieved, making it easier for medical personnel to choose the appropriate stent length according to the patient's specific situation, and improves the flexibility and efficiency of bone tissue regeneration treatment.
Smart Images
Figure CN222285696U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of bone tissue engineering, in particular to a bone tissue engineering scaffold fractal structure. Background Art
[0002] Bone tissue engineering refers to the process of separating autologous high-concentration osteoblasts, bone marrow stromal stem cells or chondrocytes, culturing and amplifying them in vitro, and then implanting them on a natural or synthetic cell scaffold or extracellular matrix that has good biocompatibility and can be gradually degraded and absorbed by the human body. This biomaterial scaffold can provide cells with a three-dimensional space for survival, which is beneficial for cells to obtain sufficient nutrients, exchange gases, and eliminate waste, allowing cells to grow on a prefabricated three-dimensional scaffold. This cell hybrid material is then implanted into the bone defect site. While the biomaterial is gradually degraded, the implanted bone cells continue to proliferate, thereby achieving the purpose of repairing bone tissue defects.
[0003] An existing bone tissue engineering scaffold fractal structure lacks the function of being able to be disassembled and spliced during use, resulting in the inability to flexibly select a suitable scaffold length for bone tissue regeneration treatment according to the patient's bone defect site during use.
[0004] For this purpose, a fractal structure of bone tissue engineering scaffold is proposed. Utility Model Content
[0005] The purpose of the utility model is to provide a fractal structure of a bone tissue engineering scaffold to solve the problems raised in the above-mentioned background technology. To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a fractal structure of a bone tissue engineering scaffold, comprising a fractal scaffold body, a scaffold top plate is installed on the top of the fractal scaffold body, and a scaffold bottom plate is installed on the bottom of the fractal scaffold body. A limiting slide groove is provided on the top of the scaffold top plate, and two disassembly and assembly sockets are symmetrically provided on the top of the limiting slide groove, and one side of the two disassembly and assembly sockets are respectively connected to the inside of the limiting slide groove, and a limiting slider is respectively installed on both sides of the bottom of the scaffold bottom plate, and the limiting slider is used in conjunction with the inside of the limiting slide groove.
[0006] Preferably, a plurality of first cell growth supports are installed at equal distances inside the fractal support body, and a plurality of second cell growth supports are installed at equal distances inside the fractal support body, and the first cell growth supports are installed perpendicularly to the second cell growth supports.
[0007] Preferably, the interiors of the first cell growth support and the second cell growth support are interconnected, and growth grooves are respectively formed in the interiors of the first cell growth support and the second cell growth support.
[0008] Preferably, the first cell growth support and the interior of the plurality of support nets formed by the growth grooves are connected via a cell drainage tube.
[0009] Preferably, the cross-sectional view of the limiting slide groove is convex-shaped, and the width of the disassembly and assembly socket is equal to the width of the bottom end of the limiting slide groove.
[0010] Compared with the prior art, the utility model provides a bone tissue engineering scaffold fractal structure, which has the following beneficial effects:
[0011] By providing a fractal support body, a support top plate, a support bottom plate, a limiting slide groove, a limiting slider and a disassembly and assembly socket, when two fractal support bodies are spliced together, the two limiting sliders can be respectively inserted into the interior of the limiting slide groove through the disassembly and assembly socket, and then the two fractal support bodies are rotated so that the limiting slider slides within the limiting slide groove, thereby splicing the two fractal support bodies together. When disassembling, the two fractal support bodies are rotated so that the limiting slider installed at the bottom end of the support bottom plate is rotated under the disassembly and assembly socket, and then the limiting slider is pulled out of the interior of the limiting slide groove through the disassembly and assembly socket to disassemble multiple fractal support bodies. The device can facilitate medical personnel to flexibly rotate the use length of the support according to the length of the patient's damaged bone when in use, which is very convenient. BRIEF DESCRIPTION OF THE DRAWINGS
[0012] Figure 1 It is a schematic diagram of the structure of the utility model when it is used in splicing;
[0013] Figure 2 It is a schematic diagram of the top view structure of the utility model;
[0014] Figure 3 For this utility model Figure 1 A schematic diagram of the enlarged structure at A in the middle;
[0015] Figure 4 For this utility model Figure 2 Schematic diagram of the enlarged structure at point B in the middle.
[0016] In the figure: 1. Fractal bracket body; 2. Limiting slide groove; 3. Limiting slider; 4. Cell drainage tube; 5. Disassembly and assembly socket; 6. First cell growth bracket; 7. Growth groove; 8. Second cell growth bracket; 9. Bracket top plate; 10. Bracket bottom plate. DETAILED DESCRIPTION
[0017] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0018] Embodiment 1: A bracket top plate 9 is installed on the top of the fractal bracket body 1, and a bracket bottom plate 10 is installed on the bottom of the fractal bracket body 1. A limiting slide groove 2 is provided on the top of the bracket top plate 9, and two disassembly and assembly sockets 5 are symmetrically provided on the top of the limiting slide groove 2. One side of the two disassembly and assembly sockets 5 are respectively connected with the inside of the limiting slide groove 2, and a limiting slider 3 is installed on both sides of the bottom of the bracket bottom plate 10. The limiting slider 3 is used in conjunction with the inside of the limiting slide groove 2. The cross-sectional view of the limiting slide groove 2 is convex, and the width of the disassembly and assembly socket 5 is equal to the width of the bottom end of the inside of the limiting slide groove 2.
[0019] Specifically, Figure 1 , Figure 2 and Figure 3 As shown, since the top and bottom of the fractal bracket body 1 are respectively installed with a bracket top plate 9 and a bracket bottom plate 10, and a limiting slide groove 2 is provided inside the bracket top plate 9, and a limiting slider 3 is respectively installed on both sides of the bottom of the bracket bottom plate 10, the limiting slider 3 installed at the bottom of the bracket bottom plate 10 can be slidably installed inside the limiting slide groove 2, so that multiple fractal bracket bodies 1 can be spliced and used. Since two disassembly sockets 5 are symmetrically provided on both sides of the top of the limiting slide groove 2, and one side of the two disassembly sockets 5 is respectively connected to the inside of the limiting slide groove 2, therefore, when two fractal bracket bodies 1 are spliced, the two limiting sliders 3 can be Insert them into the limiting slide groove 2 respectively through the disassembly and assembly socket 5, and then rotate the two fractal bracket main bodies 1 so that the limiting slider 3 slides in the limiting slide groove 2, thereby splicing the two fractal bracket main bodies 1 together. When disassembling, rotate the two fractal bracket main bodies 1 so that the limiting slider 3 installed at the bottom end of the bracket base plate 10 rotates under the disassembly and assembly socket 5, and then pull the limiting slider 3 out of the limiting slide groove 2 through the disassembly and assembly socket 5 to separate the multiple fractal bracket main bodies 1. Through this device, medical personnel can flexibly rotate the use length of the bracket according to the length of the patient's bone damage when using it, which is very convenient.
[0020] Embodiment 2: A plurality of first cell growth supports 6 are installed at equal distances inside the fractal support body 1, and a plurality of second cell growth supports 8 are installed at equal distances inside the fractal support body 1, the first cell growth support 6 and the second cell growth support 8 are installed vertically, the interiors of the first cell growth support 6 and the second cell growth support 8 are interconnected, and growth grooves 7 are respectively provided inside the first cell growth support 6 and the second cell growth support 8, and the interiors of the plurality of support nets formed by the first cell growth support 6 and the growth grooves 7 are connected through a cell drainage tube 4.
[0021] Specifically, Figure 1 , Figure 2 and Figure 4 As shown, when using the bone tissue scaffold to culture the tissue in vitro, the cell liquid can be injected into the first cell growth scaffold 6 and the second cell growth scaffold 8. The cell solution will divide and grow in the first cell growth scaffold 6 and the second cell growth scaffold 8 in a specific environment. Since the first cell growth scaffold 6 and the second cell growth scaffold 8 are connected to the interiors of multiple first cell growth scaffolds 6 and second cell growth scaffolds 8 through the cell drainage tube 4, the cell solution can grow in all directions inside the fractal scaffold body 1. Since the first cell growth scaffold 6 and the second cell growth scaffold 8 are provided with growth grooves 7, the cells can extend out of the first cell growth scaffold 6 and the second cell growth scaffold 8 after growth through the growth grooves 7, and fuse with each other, thereby improving the strength of the cells after growth and fusion, thereby improving the treatment effect on the damaged area of the patient's bone tissue.
[0022] Working principle: When in use, a bracket of appropriate length is selected according to the size and length of the damaged bone area of the patient. Since the top and bottom of the fractal bracket main body 1 are respectively installed with a bracket top plate 9 and a bracket bottom plate 10, and a limiting slide groove 2 is provided inside the bracket top plate 9, and a limiting slider 3 is respectively installed on both sides of the bottom of the bracket bottom plate 10, therefore, the limiting slider 3 installed at the bottom of the bracket bottom plate 10 can be slidably installed inside the limiting slide groove 2, so that multiple fractal bracket main bodies 1 can be spliced and used. Since two disassembly and assembly sockets 5 are symmetrically provided on both sides of the top of the limiting slide groove 2, and one side of the two disassembly and assembly sockets 5 is respectively connected with the inside of the limiting slide groove 2, therefore, when two fractal bracket main bodies 1 are spliced, the two limiting sliders 3 can be respectively inserted into the inside of the limiting slide groove 2 through the disassembly and assembly sockets 5, and then the two fractal bracket main bodies 1 are rotated so that the limiting slider 3 slides inside the limiting slide groove 2 within a limited position, thereby splicing the two fractal bracket main bodies 1. When splitting, the two fractal support bodies 1 are rotated to rotate the limit slider 3 installed at the bottom end of the support base plate 10 to the bottom of the disassembly socket 5, and then the limit slider 3 is pulled out of the limit slide groove 2 through the disassembly socket 5 to split the multiple fractal support bodies 1. After selecting a support of a suitable length, the cells are cultured and amplified and then implanted into the interior of the fractal support body 1. Since the interiors of the first cell growth support 6 and the second cell growth support 8 are connected to the interiors of the multiple first cell growth supports 6 and the second cell growth support 8 through the cell drainage tube 4, the cell solution can grow in all directions inside the fractal support body 1. Since the interiors of the first cell growth support 6 and the second cell growth support 8 are provided with growth grooves 7, the cells can be extended out of the interiors of the first cell growth support 6 and the second cell growth support 8 after growth through the growth grooves 7, and fuse with each other to improve the strength of the cells after growth and fusion, and then implanted together into the damaged bone part of the patient for use.
[0023] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.
Claims
1. A bone tissue engineering scaffold fractal structure, comprising a fractal scaffold body (1), characterized in that: A bracket top plate (9) is installed at the top of the fractal bracket body (1), and a bracket bottom plate (10) is installed at the bottom of the fractal bracket body (1). A limit slide groove (2) is provided at the top of the bracket top plate (9), and two disassembly and assembly sockets (5) are symmetrically provided at the top of the limit slide groove (2), and one side of the two disassembly and assembly sockets (5) are respectively connected to the inside of the limit slide groove (2). A limit slider (3) is installed on both sides of the bottom of the bracket bottom plate (10), and the limit slider (3) is used in conjunction with the inside of the limit slide groove (2).
2. A bone tissue engineering scaffold fractal structure according to claim 1, characterized in that: A plurality of first cell growth supports (6) are installed at equal distances inside the fractal support body (1), and a plurality of second cell growth supports (8) are installed at equal distances inside the fractal support body (1), wherein the first cell growth supports (6) and the second cell growth supports (8) are installed vertically.
3. A bone tissue engineering scaffold fractal structure according to claim 2, characterized in that: The interiors of the first cell growth support (6) and the second cell growth support (8) are interconnected, and growth grooves (7) are respectively provided in the interiors of the first cell growth support (6) and the second cell growth support (8).
4. A bone tissue engineering scaffold fractal structure according to claim 3, characterized in that: The first cell growth support (6) and the plurality of support nets formed by the growth grooves (7) are connected to each other through the cell drainage tube (4).
5. The bone tissue engineering scaffold fractal structure according to claim 1, characterized in that: The cross-sectional view of the limiting slide groove (2) is in the shape of a convex letter, and the width of the disassembly and assembly socket (5) is equal to the width of the bottom end of the limiting slide groove (2).