Full-automatic dry-type fluorescence immunoassay device

Abstract

The utility model relates to the technical field of medical detection, in particular to a full-automatic dry-type fluorescence immunoassay device. The working platform is used for mounting the whole device; the cap screwing manipulator device is used for clamping and moving the sample test tube to move on the working platform front and back and left and right, and the cap screwing manipulator device is matched with the lower test tube clamping device and can unscrew the test tube; the pipetting and cup distributing module is located on one side of the cap screwing manipulator device, and the pipetting and cup distributing module is provided with two identical sample adding needle devices. A processing system of the device is controlled by a single-chip microcomputer MCU and other schemes, and the device has the advantages of simple peripheral matching, low utilization rate of structural space, compact structure, small size of the whole machine, light weight and the like. Manual operation is replaced by automatic operation, so that the detection efficiency is greatly improved, heavy detection tasks are dealt with, meanwhile, the operation that experimenters make direct contact with samples is reduced, the infection risk is avoided, and the safety guarantee is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of medical detection, in particular to a full-automatic dry fluorescent immunoassay device. Background Art

[0002] Dry immunofluorescence analysis is clinically used in the detection of antigens and antibodies of biological sources such as viruses, bacteria, and proteases. It is widely used in life science fields such as medical testing, clinical diagnosis, and drug development.

[0003] At present, hospitals and related medical laboratories all manually add reagents and samples to gold label cards by laboratory personnel. The samples to be tested are generally temporarily stored in sample tubes. Before performing biological detection and analysis, the samples need to be transferred from the sample tubes to the holes of the reaction plate one by one. This process is extremely cumbersome and involves scanning codes, information verification, capping, liquid transfer, capping, etc. In the early detection process, the above links were completed manually, which was time-consuming, labor-intensive, inefficient, and had a high error rate. Utility Model Content

[0004] The purpose of the utility model is to provide a fully automatic dry fluorescent immunoassay device to solve the above-mentioned problems.

[0005] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a fully automatic dry fluorescent immunoassay device, comprising;

[0006] A working platform, the working platform is used to install the overall device;

[0007] A capping manipulator device, which is used to clamp and move the sample test tube forward, backward, left and right on the working platform. The capping manipulator device cooperates with the lower test tube clamping device to unscrew the test tube;

[0008] A pipetting and cupping module, which is located on one side of the capping robot device, and has two identical sample adding needle devices, which can be brought close to or separated by a guide rail arranged in the middle, one of which is used to move the sample, and the other is used to move the diluent;

[0009] A card clamping manipulator device 1, wherein the card clamping manipulator device 1 is used to clamp the gold label card in the gold label card activity space to realize forward and backward and left and right movement;

[0010] A card pushing assembly, which is arranged on the left side of the working platform and outside the card placing mechanism, and is used to push the gold-labeled card of the card placing mechanism to the waiting area of ​​the working platform, and an incubation platform is arranged between the waiting area and the pipetting and cupping module;

[0011] A detection module is arranged on one side of the card pushing assembly, and is used to detect the specimen clamped by the second clamping manipulator device. A push-out port is arranged on one side of the detection module.

[0012] Preferably, the capping robot device comprises a lifting motor, the main shaft of the lifting motor drives the first screw rod to move the mounting frame up and down, a clamping motor is arranged on the mounting frame, a fixing seat is arranged at the bottom of the clamping motor, racks are arranged opposite to each other on the fixing seat, two racks are connected by a gear at the output end of the clamping motor, two clamping blocks are arranged at the bottom of the rack, a transverse sliding mechanism and a longitudinal sliding mechanism are arranged on one side of the capping robot device, the transverse sliding mechanism slides transversely on the working platform, and the longitudinal sliding mechanism slides longitudinally on the working platform, and a barcode scanner A is arranged on one side of the capping robot device;

[0013] The lower test tube clamping device includes a tube clamping motor, one side of the tube clamping motor is fixedly connected to a test tube seat, and a test tube placement port is arranged on the top, and a test tube gear is arranged at the output end of the tube clamping motor, and two gear seats are meshed on the test tube gear, and clamping plates are arranged on the two gear seats, and a soft block is arranged on the inner side of the clamping plate.

[0014] Preferably, the sample adding needle device comprises a guide rail motor 1, one side of the guide rail motor 1 is fixedly connected with a lifting frame, a lifting screw is arranged on the lifting frame, the top end of the lifting screw and the output end of the guide rail motor 1 are both fixedly connected with a pulley, the two pulleys are connected through a transmission belt transmission, a driving motor 1 is arranged on one side of the lifting frame, a walking wheel is arranged at the output end of the driving motor 1, the walking wheel is located in a slide rail plate, the slide rail plate is arranged on the longitudinal track on the working platform, a ball seat is arranged on the lifting screw, a guide rail motor 2 is fixedly connected to the ball seat, a syringe guide is arranged on the guide rail motor 2, a suction pump is arranged on the syringe guide, a transition pipe is arranged at the bottom end of the suction pump, and a ball valve is fixedly connected to the upper end of the transition pipe;

[0015] It also includes a second drive motor, the output end of which is provided with a drive pulley, the drive pulley is provided with a transmission belt, both ends of the transmission belt are rotatable on the working platform, the transmission belt is provided with a slider, and the slider moves laterally on the slide rail of the working platform.

[0016] Preferably, the clamping robot device 1 includes a slide seat slidably arranged on a horizontal track on the working platform, a carrier plate is arranged on the top of the slide seat, the two carrier plates are fixedly connected by a longitudinal track, a driving motor 3 is arranged on one side of the longitudinal carrier plate, the driving motor 3 moves back and forth on the longitudinal track, a lifting motor is fixedly connected to the carrier plate, a lifting screw rod is fixedly arranged on the output end of the lifting motor, a ball sleeve is sleeved on the lifting screw rod, a clamping motor is fixedly connected to the ball sleeve, a guide gear is fixedly connected to the output end of the clamping motor, a tooth foot block is arranged at a corresponding position on the guide gear, a gripper is arranged on the tooth foot block, and one end of the gripper is elastically connected to the motor frame through a first tension spring;

[0017] It also includes a transverse conveyor belt, one end of which is sleeved on a fixed wheel fixed on the working platform and a driving motor four fixed on the working platform, and the other end of the transverse conveyor belt is sleeved on the output end of the driving motor four and fixedly connected to a transmission wheel, and an auxiliary wheel is used to limit the transverse conveyor belt.

[0018] Preferably, the card pushing assembly includes two lateral displacement motors, the output end of the lateral displacement motor is fixedly connected with a lateral displacement screw rod, a card pushing plate is arranged on the lateral displacement screw rod, a baffle plate is arranged on the card pushing plate, and the card pushing plate moves in the pushing groove of the baffle plate, the output end of the longitudinal displacement motor is provided with a longitudinal adjustment screw rod, the bases of the two lateral displacement motors move back and forth on the longitudinal adjustment screw rod, the outer end of the lateral displacement screw rod is fixedly connected with a mounting plate, a forward and reverse motor is fixedly connected with the mounting plate, the output end of the forward and reverse motor is fixedly connected with a transmission wheel, a transmission wheel is arranged on the top of the mounting plate, the two transmission wheels are connected through a belt group, a flexible belt is fixedly connected to one side of the belt group, a photoelectric probe is arranged at one end of the flexible belt, and a barcode scanner is arranged at the lower end of the flexible belt.

[0019] Preferably, the clamping robot device 2 includes a driving motor 5, the output end of the driving motor 5 is provided with a toothed belt pulley, the toothed belt pulley is provided with a toothed belt, both ends of the toothed belt are provided on a longitudinal slide rail provided on the working platform, the toothed belt is fixedly connected with a slide plate, the slide plate moves back and forth on the longitudinal slide rail, a transverse driving motor is fixedly connected to a mounting base provided on the driving motor 5, a transverse slide plate is provided at the output end of the transverse driving motor, a longitudinal slide rail is provided on the transverse slide plate, a servo motor is provided on the other side of the mounting base, a driving gear is provided at the output end of the servo motor, a guide rack that moves relatively is provided on the driving gear, and a clamping claw is elastically hinged on the servo motor base through a second tension spring.

[0020] Preferably, the card placing mechanism comprises a plurality of equidistantly arranged lower card boxes, the bottom of the lower card boxes is provided with an elastic lifting plate, and the top end of the elastic lifting plate is located on one side of the card pushing plate path for supporting the standard card below.

[0021] Preferably, it also includes a computer control terminal, which is communicatively connected to a main control board, and the main control board includes: MCU1, MCU2 and MCU3, wherein:

[0022] MCU1 is connected to the card pushing component, the incubation platform, the barcode scanner, the detection module and the second card clamping robot device;

[0023] MCU2 is connected to group a and group b of sample adding modules;

[0024] MCU3 is communicatively connected with the capping robot device and the barcode scanner A.

[0025] Technical effects and advantages of the utility model:

[0026] The processing system of this device is controlled by a single-chip microcomputer (MCU) and other solutions. It has simple peripherals, low structural space utilization, and a compact structure, which makes the whole machine small in size and relatively light in weight. It replaces manual operation through automated operation, thereby greatly improving inspection efficiency and coping with heavy inspection tasks. At the same time, it reduces the direct contact of laboratory personnel with samples, avoids infection risks, and improves safety assurance. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a schematic diagram of a fully automatic dry fluorescent immunoassay device of the utility model;

[0028] Figure 2 It is a schematic diagram of a card clamping manipulator device 1 in a fully automatic dry fluorescent immunoassay device of the utility model;

[0029] Figure 3 This is a bottom view of a fully automatic dry fluorescent immunoassay device of the utility model;

[0030] Figure 4 This is a front schematic diagram of a card pusher assembly in a fully automatic dry fluorescent immunoassay device of the utility model;

[0031] Figure 5 It is a schematic diagram of a second card clamping manipulator device in a fully automatic dry fluorescent immunoassay device of the utility model;

[0032] Figure 6 It is a schematic diagram of a top view of a second card clamping manipulator device in a fully automatic dry fluorescent immunoassay device of the utility model;

[0033] Figure 7It is a partial schematic diagram of a card clamping manipulator device 1 in a fully automatic dry fluorescent immunoassay device of the utility model;

[0034] Figure 8 It is a schematic diagram of a pipetting and cupping module in a fully automatic dry fluorescent immunoassay device of the utility model;

[0035] Fig. 9 It is a schematic diagram of a capping manipulator device and a liquid transfer cup module in a fully automatic dry fluorescent immunoassay device of the utility model;

[0036] Fig.10 It is a schematic diagram of a pipetting and cupping module in a fully automatic dry fluorescent immunoassay device of the utility model;

[0037] Fig.11 It is a schematic diagram of a lower test tube clamping device in a fully automatic dry fluorescent immunoassay device of the utility model;

[0038] Fig.12 The utility model is a functional block diagram of a fully automatic dry fluorescent immunoassay device. DETAILED DESCRIPTION

[0039] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0040] Reference Figures 1 to 12 The utility model provides a fully automatic dry fluorescent immunoassay device, comprising: a working platform 1, a capping robot device 10, a pipetting and cupping module 2, a card clamping robot device 9, a card pushing component 6, a detection module 8 and a pushing port 12.

[0041] The working platform 1 is described in detail below:

[0042] Reference Figures 1 to 3The working platform 1 is used to install the whole device. The capping robot device 10, the pipetting and cupping module 2, the clamping robot device 1 9, the card pushing assembly 6 and the detection module 8 are all installed on the working platform 1. The capping robot device 10, the pipetting and cupping module 2, the clamping robot device 1 9 and the clamping robot device 2 7 can all move forward, backward, left and right on the working platform 1. The working platform 1 includes an operating platform 104. The operating platform 104 is provided with a transverse track 101 near the card pushing assembly 6. The top of the operating platform 104 is provided with a There is an upper slide rail 103, the capping manipulator device 10 and the pipetting and cupping module 2 move laterally on the upper slide rail 103, the operating platform 104 includes a platform area, the platform area is provided with a waiting area, a temperature control device is provided on one side of the waiting area, and is connected to the computer control end. The temperature of the area can be controlled to incubate the gold label card reagent dripped with the reagent. A reagent placement rack and a diluent bottle rack are provided below the pipetting and cupping module 2 for placing the reaction liquid, and a test tube placement rack is provided below the capping manipulator device 10;

[0043] The following is a detailed description of the capping process of the capping robot device 10:

[0044] Reference Figures 9 to 11 The capping manipulator device 10 is used to clamp and move the sample test tube forward, backward, left and right on the working platform 1. The capping manipulator device 10 cooperates with the lower test tube clamping device 11 to unscrew the test tube;

[0045] The capping robot device 10 includes a lifting motor 1001, the main shaft of the lifting motor 1001 drives the first screw rod 1006 to move the mounting frame 1007 up and down, and a ball sleeve is arranged on the mounting frame 1007, and the ball sleeve is arranged on the first screw rod 1006. The mounting frame 1007 can move upward or downward during the forward and reverse rotation of the first screw rod 1006, and then can move downward to clamp the test tube, and then lift the test tube upward after clamping. A clamping motor 1002 is arranged on the mounting frame 1007, and the clamping motor 1002 can be reversed forward and backward, and is used to drive the test tube to be clamped. A fixed seat 1003 is arranged at the bottom of the clamping motor 1002, and racks are arranged opposite to each other on the fixed seat 1003. The two racks are connected by a gear at the output end of the clamping motor 1002, and two clamping blocks 1 are arranged at the bottom of the rack. 004, a rotating motor is arranged on the clamping block 1004, which is used for clamping the top of the test tube with two racks when the output end of the clamping motor 1002 rotates. After the test tube is placed in the lower clamping test tube device 11, the lower clamping test tube device 11 cooperates with the rotating motor to rotate the cap part of the test tube, thereby keeping the test tube in an open state, which is convenient for the sample needle device to take liquid. A transverse sliding mechanism 1005 and a longitudinal sliding mechanism are arranged on one side of the capping manipulator device 10. The transverse sliding mechanism 1005 slides transversely on the working platform 1, and the longitudinal sliding mechanism slides longitudinally on the working platform 1. A barcode scanner A is arranged on one side of the capping manipulator device 10. The barcode scanner A is used to scan and process the clamped reagent tube and enter it, which is compatible with the gold label card QR code to facilitate detection information matching;

[0046] Reference Fig.11 The lower test tube clamping device 11 includes a tube clamping motor 111, one side of the tube clamping motor 111 is fixedly connected to a test tube seat 116, and a test tube placement port 117 is arranged on the top, and a test tube gear 112 is arranged at the output end of the tube clamping motor 111, and two gear seats 113 are meshed on the test tube gear 112, and clamping plates 115 are arranged on the two gear seats 113, and a soft block 114 is arranged on the inner side of the clamping plate 115.

[0047] When placing the test tube in the lower test tube clamping device 11, after the bottom end of the test tube is aligned with the test tube placement port 117, when the test tube gear 112 on the output end of the tube clamping motor 111 rotates, the two gear seats 113 are relatively close to each other, the clamping plates 115 are close to each other, and the soft block 114 contacts the surface of the test tube to clamp the test tube to maintain a stable state, and the sample adding needle device can take liquid from the test tube.

[0048] The following is a detailed description of the operation process of the pipetting and cupping module 2:

[0049] Reference Figure 8 and Fig. 9The pipetting and cupping module 2 is located on one side of the capping manipulator device 10. The pipetting and cupping module 2 has two identical sample adding needle devices. The two sample adding needle devices can be approached or separated through a guide rail arranged in the middle. One of the sample adding needle devices is used to move the sample, and the other is used to move the diluent.

[0050] The sample adding needle device includes a guide rail motor 21, one side of the guide rail motor 21 is fixedly connected with a lifting frame 24, the lifting frame 24 is provided with a lifting screw 25, the top of the lifting screw 25 and the output end of the guide rail motor 21 are fixedly connected with a pulley 22, the two pulleys 22 are connected through a conveyor belt 23, one side of the lifting frame 24 is provided with a driving motor 26, the output end of the driving motor 26 is provided with a walking wheel, the walking wheel is located in a slide plate 29, the slide plate 29 is arranged on the longitudinal track on the working platform 1, the lifting screw 25 is provided with a ball seat, the ball seat is fixedly connected with a guide rail motor 28, the guide rail motor 28 is provided with a syringe guide 27, the syringe guide 27 is provided with a suction pump 210, the bottom end of the suction pump 210 is provided with a transition pipe 211, and the upper end of the transition pipe 211 is fixedly connected with a ball valve 212;

[0051] The two sample adding needle devices absorb the test tube liquid and the reaction liquid in the test tube respectively. The guide motor 1 21 drives the lifting screw 25 to rotate through the pulley 22 and the conveyor belt 23. The ball seat on the lifting screw 25 can move up and down. The guide motor 28 can drive the syringe guide 27 to move up and down to take the liquid. When taking the liquid, the two sample adding needle devices can take the liquid separately or synchronously. The transition tube 211 on the suction pump 210 extends into the test tube. After the ball valve 212 contacts the inner wall of the test tube, the test tube can be clamped. Specifically, the ball valve 212 It is spherical with a drainage channel, and there is an adsorption hole arranged on the outer wall connected to the drainage channel. When the ball valve 212 enters the test tube and contacts the inner wall of the test tube, the silicone material on the surface of the ball valve 212 can be compressed. After the adsorption hole fits the tube wall, when the suction pump 210 sucks, a negative pressure is formed in the test tube, and the adsorption hole can form an adsorption state with the inner wall of the test tube, and then the adsorption effect can be used to maintain the firmness of the sampling needle when taking liquid. When the sampling is completed, the suction pump 210 stops sucking. At this time, the sampling needle loses its adsorption force, and the sampling needle can be replaced after the sampling is completed.

[0052] Reference Fig. 9 , and also includes a driving motor 213. The output end of the driving motor 213 is provided with a driving pulley 214. The driving pulley 214 is provided with a conveying belt 216. Both ends of the conveying belt 216 are rotatable on the working platform 1. The conveying belt 216 is provided with a slider, and the slider moves laterally on the slide rail of the working platform 1.

[0053] The output end of the second driving motor 213 drives the conveyor belt 216 to rotate. At this time, the conveyor belt 216 rotates on the working platform 1, and then the slider on the conveyor belt 216 can slide, so that the pipetting and cupping module 2 can move horizontally. When moving vertically, the walking wheels on the slide plate 29 can move on the longitudinal track.

[0054] The following is a detailed description of the operation process of the card clamping robot device 1 9 and the card clamping robot device 2 7:

[0055] It should be noted that the card clamping robot device 1 9 and the card clamping robot device 2 7 can be set as one. When one is set, the card clamping robot device 1 9 needs to move the gold-labeled card for dripping reagent to the incubation platform 4. After the incubation is completed, the gold-labeled card needs to be moved to the position of the detection module 8. At this time, the gold-labeled card at the pipetting and cupping module 2 needs to wait. When the card clamping robot device 1 9 and the card clamping robot device 2 7 are set, they can be operated separately.

[0056] Reference Fig. 9 and Figure 7 , the clamping manipulator device 19 is used to clamp the gold label card in the activity space of the gold label card to realize forward and backward and left and right movement; the clamping manipulator device 19 includes a slide 96 slidably arranged on the horizontal track 101 on the working platform 1, a carrier plate 95 is arranged on the top of the slide 96, and the two carrier plates 95 are fixedly connected by a longitudinal track 102, and a driving motor 3 92 is arranged on one side of the longitudinal carrier plate 95. The driving motor 3 92 moves forward and backward on the longitudinal track 102, and a lifting motor 91 is fixedly connected to the carrier plate 95, and a lifting screw rod is fixed to the output end of the lifting motor 91, and a ball sleeve is sleeved on the lifting screw rod, and a clamping claw motor 911 is fixedly connected to the ball sleeve, and a guide gear 912 is fixedly connected to the output end of the clamping claw motor 911, and a tooth foot block 913 is arranged at a corresponding position on the guide gear 912, and a gripper 94 is arranged on the tooth foot block 913, and one end of the gripper 94 is elastically connected to the motor frame through a first tension spring 914;

[0057] During longitudinal movement, a walking wheel is provided on the output end of the driving motor 3 92 to roll on the longitudinal track 102, thereby driving the overall longitudinal displacement on the longitudinal track 102, and the lifting motor 91 can make the clamping claw part move up and down to clamp the reagent card. During clamping, the guide gear 912 on the clamping claw motor 911 can move the tooth foot block 913, and the gripper 94 on the tooth foot block 913 can perform a gripping operation, so that the reagent card can be clamped and moved.

[0058] It also includes a transverse conveyor belt 97, one end of which is sleeved on a fixed wheel fixed on the working platform 1, and on a driving motor 98 fixed on the working platform 1, and the other end of the transverse conveyor belt 97 is sleeved on the output end of the driving motor 98 and fixedly connected to a transmission wheel 99, and an auxiliary wheel 910 is used to limit the transverse conveyor belt 97.

[0059] When lateral movement is required, the driving motor 98 drives the lateral conveyor belt 97 to rotate, and the slide 96 connected to the lateral conveyor belt 97 moves left and right on the lateral track 101.

[0060] Reference Figure 5 The clamping robot device 2 7 includes a driving motor 5 71, and a toothed belt pulley 72 is provided at the output end of the driving motor 5 71. A toothed belt is provided on the toothed belt pulley 72. Both ends of the toothed belt are provided on the longitudinal slide rail provided on the working platform 1. A slide plate 73 is fixedly connected to the toothed belt. The slide plate 73 moves back and forth on the longitudinal slide rail. A transverse driving motor 79 is fixedly connected to the mounting base provided on the driving motor 5 71. A transverse slide plate 75 is provided at the output end of the transverse driving motor 79. The longitudinal slide rail is provided on the transverse slide plate 75. The driving method is the same as the moving method of the clamping robot device 1 9. A servo motor 76 is provided on the other side of the mounting base. A driving gear is provided at the output end of the servo motor 76. A guide rack 74 that moves relatively is provided on the driving gear. A clamping claw 78 is elastically hinged on the base of the servo motor 76 through a second tension spring 77.

[0061] The operation process of the card pushing assembly 6 is described in detail below:

[0062] Figures 2 to 4 The card pushing assembly 6 is arranged on the left side of the working platform 1 and outside the card placing mechanism 5. The card pushing assembly 6 is used to push the gold label card of the card placing mechanism 5 to the waiting area of ​​the working platform 1. The waiting area and the liquid transfer cup module 2 are provided with an incubation platform 4. The card placing mechanism 5 includes a plurality of lower card boxes arranged at equal distances. The bottom of the lower card box is provided with an elastic lifting plate, and the top of the elastic lifting plate is located on one side of the card pushing plate path, which is used to support the label card below.

[0063] The card pushing assembly 6 includes two lateral displacement motors 69, the output end of the lateral displacement motor 69 is fixedly connected with a lateral displacement screw rod 691, a card pushing plate is arranged on the lateral displacement screw rod 691, a baffle plate 61 is arranged on the card pushing plate, and the card pushing plate moves in the pushing groove of the baffle plate 61, a longitudinal adjustment screw rod is arranged at the output end of the longitudinal displacement motor 610, the machine bases of the two lateral displacement motors 69 move back and forth on the longitudinal adjustment screw rod, the outer end of the lateral displacement screw rod 691 is fixedly connected with a mounting plate 63, a forward and reverse motor 62 is fixedly connected to the mounting plate 63, a transmission wheel 66 is fixedly connected to the output end of the forward and reverse motor 62, a transmission wheel 66 is arranged at the top of the mounting plate 63, the two transmission wheels 66 are connected by a belt group 67, a flexible belt 64 is fixedly connected to one side of the belt group 67, a photoelectric probe 65 is arranged at one end of the flexible belt 64, and a barcode scanner 68 is arranged at the lower end of the flexible belt 64.

[0064] When the card pushing assembly 6 is in use, the longitudinal displacement motor 610 drives the longitudinal adjustment screw to rotate, and the bases of the two transverse displacement motors 69 located on the longitudinal adjustment screw can move in relative directions or opposite directions, and then the transverse displacement screw 691 located on the transverse displacement motor 69 can drive the movement, and the forward and reverse motor 62 installed on the carrier plate 63 moves accordingly. After the forward and reverse motor 62 can move to the specified position, the forward and reverse motor 62 drives the transmission wheel 66 to rotate, and then the belt group 67 can make the flexible belt 64 move up and down, and the photoelectric probe 65 detects the gold label card of the card placing mechanism 5 and detects the quantity inside, and the barcode scanner 68 scans the gold label, and the card pushing plate can push the gold label card to the position of the waiting area on the transverse displacement screw 691.

[0065] Detection module 8, detection module 8 is arranged on one side of card pushing assembly 6, detection module 8 is used to detect the specimen clamped by clamping manipulator device 2 7, one side of detection module 8 is provided with a push-out port 12, detection module 8 is specifically a dry immunofluorescence analyzer, dry immunofluorescence analyzer detects the target substance in the sample through the fluorescent signal. First, the sample enters the detector through the sample hole. Then, the fluorescently labeled antibody is stimulated by the fluorescent probe, and the fluorescently labeled antibody is excited to fluorescence. After the fluorescent signal is collected and amplified by the receiver, the content of the target substance in the sample is calculated through software analysis, which can accurately and quickly diagnose various diseases and provide doctors with a more scientific basis for diagnosis and treatment.

[0066] It also includes a computer control terminal, which is communicatively connected to a main control board, and the main control board includes: MCU1, MCU2 and MCU3, wherein: MCU1 is communicatively connected to a card pushing component 6, an incubation platform 4, a barcode scanner 68, a detection module 8 and a second card clamping manipulator device 7; MCU2 is communicatively connected to a group a sample adding module and a group b sample adding module, and the group a sample adding module and the group b sample adding module are specifically two sample adding needle devices;

[0067] The MCU3 is communicatively connected with the capping robot device 10 and the barcode scanner A.

[0068] A detection method of a fully automatic dry fluorescent immunoassay device comprises the following steps:

[0069] In the first step, the barcode scanner 68 on the card pushing assembly 6 scans the reagent card on the card placing mechanism 5, and the barcode scanner 68 enters the read information into the computer control terminal, and pushes the corresponding reagent card to the waiting area; the capping robot device 10 clamps the test tube, and the barcode scanner A on the capping robot device 10 scans the test tube and enters the read information into the computer control terminal, and moves to the specified position to unscrew the test tube cover;

[0070] In the second step, the two sample adding needle devices on the pipetting and cupping module 2 respectively absorb the sample liquid from the sample test tube and the reaction liquid from the reaction liquid or diluent. During this process, the capping robot device 10 avoids the two sample adding needle devices. The sample adding module group a completes the sample test tube, and the sample adding module group b completes the reaction liquid from the reaction liquid or diluent, and adds it to the gold label card according to the specified amount. At this time, the clamping robot device 9 clamps the reagent card, and the pipetting and cupping module 2 and the capping robot device 10 avoid it;

[0071] In the third step, the card clamping robot device 1 9 clamps the reagent card to the position of the incubation platform 4. After incubation for a specified time, the card clamping robot device 2 7 clamps the reagent card from the incubation platform 4 and moves it to the detection position. The detection module 8 detects the reagent card. The detection module 8 calculates the detection data and feeds it back to the CPU of the computer control end to complete the detection. The discarded reagent card after the detection is pushed out from the ejection port 12.

[0072] Finally, it should be noted that the above is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present utility model shall be included in the protection scope of the present utility model.

Claims

1. A fully automatic dry fluorescent immunoassay device, characterized in that: include; A working platform (1), wherein the working platform (1) is used to install the overall device; A capping manipulator device (10), the capping manipulator device (10) is used to clamp and move the sample test tube on the working platform (1) to move forward, backward, left and right. The capping manipulator device (10) cooperates with the lower test tube clamping device (11) to unscrew the test tube; a liquid transfer cup module (2) located on one side of the capping robot device (10), the liquid transfer cup module (2) having two identical sample adding needle devices, the two sample adding needle devices being able to be brought close to or separated by a guide rail arranged in the middle, one of the sample adding needle devices being used to move the sample, and the other being used to move the diluent; A card clamping manipulator device (9), wherein the card clamping manipulator device (9) is used to clamp the gold label card in the gold label card activity space to realize forward and backward and left and right movement; A card pushing assembly (6), the card pushing assembly (6) being arranged on the left side of the working platform (1) and outside the card placing mechanism (5), the card pushing assembly (6) being used to push the gold-labeled card of the card placing mechanism (5) to the waiting transfer area of ​​the working platform (1), and an incubation platform (4) being arranged between the waiting transfer area and the liquid transfer cup module (2); A detection module (8), wherein the detection module (8) is arranged on one side of the card pushing assembly (6), and the detection module (8) is used to detect the specimen clamped by the second clamping manipulator device (7). A push-out opening (12) is arranged on one side of the detection module (8).

2. A fully automatic dry fluorescent immunoassay device according to claim 1, characterized in that: The capping robot device (10) comprises a lifting motor (1001), the main shaft of which drives a first screw rod (1006) to move a mounting frame (1007) up and down, a clamping motor (1002) is arranged on the mounting frame (1007), a fixing seat (1003) is arranged at the bottom of the clamping motor (1002), racks are arranged opposite to each other on the fixing seat (1003), the two racks are connected by a gear at the output end of the clamping motor (1002), two clamping blocks (1004) are arranged at the bottom of the rack, a transverse sliding mechanism (1005) and a longitudinal sliding mechanism are arranged on one side of the capping robot device (10), the transverse sliding mechanism (1005) slides transversely on the working platform (1), and the longitudinal sliding mechanism slides longitudinally on the working platform (1), and a barcode scanner A is arranged on one side of the capping robot device (10); The lower test tube clamping device (11) comprises a tube clamping motor (111), one side of the tube clamping motor (111) is fixedly connected to a test tube seat (116), and a test tube placement opening (117) is arranged on the top, and a test tube gear (112) is arranged at the output end of the tube clamping motor (111), and two tooth seats (113) are meshed on the test tube gear (112), and clamping plates (115) are arranged on the two tooth seats (113), and a soft block (114) is arranged on the inner side of the clamping plate (115).

3. A fully automatic dry fluorescent immunoassay device according to claim 2, characterized in that: The sample adding needle device comprises a guide rail motor (21), one side of the guide rail motor (21) is fixedly connected to a lifting frame (24), a lifting screw (25) is arranged on the lifting frame (24), the top end of the lifting screw (25) and the output end of the guide rail motor (21) are both fixedly connected to a pulley (22), the two pulleys (22) are connected by transmission through a conveyor belt (23), a driving motor (26) is arranged on one side of the lifting frame (24), and a walking wheel is arranged at the output end of the driving motor (26), The walking wheel is located in the slide rail plate (29), the slide rail plate (29) is arranged on the longitudinal track on the working platform (1), the lifting screw rod (25) is provided with a ball seat, the ball seat is fixedly connected with the guide rail motor 2 (28), the guide rail motor 2 (28) is provided with a syringe guide rail (27), the syringe guide rail (27) is provided with a suction pump (210), the bottom end of the suction pump (210) is provided with a transition pipe (211), and the upper end of the transition pipe (211) is fixedly connected with a ball valve (212); It also comprises a second drive motor (213), the output end of the second drive motor (213) is provided with a drive pulley (214), a transmission belt (216) is provided on the drive pulley (214), both ends of the transmission belt (216) are rotatable on the working platform (1), a slider is provided on the transmission belt (216), and the slider moves laterally on the slide rail of the working platform (1).

4. A fully automatic dry fluorescent immunoassay device according to claim 3, characterized in that: The clamping robot device (9) comprises a slide seat (96) slidably arranged on a transverse track (101) on a working platform (1), a carrier plate (95) is arranged on the top of the slide seat (96), two carrier plates (95) are fixedly connected via a longitudinal track (102), a driving motor (92) is arranged on one side of the longitudinal carrier plate (95), the driving motor (92) is displaced forward and backward on the longitudinal track (102), and a lifting motor (95) is fixedly connected to the carrier plate (95). 1), a lifting screw is fixed to the output end of the lifting motor (91), a ball bearing seat is sleeved on the lifting screw, a clamping motor (911) is fixedly connected to the ball bearing seat, a guide gear (912) is fixedly connected to the output end of the clamping motor (911), a tooth foot block (913) is arranged at a corresponding position on the guide gear (912), a gripper (94) is arranged on the tooth foot block (913), and one end of the gripper (94) is elastically connected to the motor frame through a first tension spring (914); It also includes a transverse conveyor belt (97), one end of which is sleeved on a fixed wheel fixed on the working platform (1), a driving motor four (98) is fixed on the working platform (1), the other end of the transverse conveyor belt (97) is sleeved on the output end of the driving motor four (98) and is fixedly connected to a transmission wheel (99), and an auxiliary wheel (910) is used to limit the transverse conveyor belt (97).

5. A fully automatic dry fluorescent immunoassay device according to claim 4, characterized in that: The card pushing assembly (6) comprises two transverse displacement motors (69), the output ends of the transverse displacement motors (69) are fixedly connected to transverse displacement screw rods (691), a card pushing plate is arranged on the transverse displacement screw rods (691), a baffle plate (61) is arranged on the card pushing plate, and the card pushing plate moves in a pushing groove of the baffle plate (61), and a longitudinal adjustment screw rod is arranged at the output end of the longitudinal displacement motor (610), the machine bases of the two transverse displacement motors (69) move forward and backward on the longitudinal adjustment screw rods, and the outer ends of the transverse displacement screw rods (691) are fixedly connected to the longitudinal adjustment screw rods. A mounting plate (63) is provided, a forward and reverse motor (62) is fixedly connected to the mounting plate (63), a transmission wheel (66) is fixedly connected to the output end of the forward and reverse motor (62), a transmission wheel (66) is arranged at the top of the mounting plate (63), two transmission wheels (66) are connected by a belt group (67), a flexible belt (64) is fixedly connected to one side of the belt group (67), a photoelectric probe (65) is arranged at one end of the flexible belt (64), and a barcode scanner (68) is arranged at the lower end of the flexible belt (64).

6. A fully automatic dry fluorescent immunoassay device according to claim 5, characterized in that: The clamping robot device 2 (7) comprises a driving motor 5 (71), the output end of the driving motor 5 (71) is provided with a toothed belt pulley (72), the toothed belt pulley (72) is provided with a toothed belt, both ends of the toothed belt are provided on a longitudinal slide rail provided on the working platform (1), the toothed belt is fixedly connected with a slide plate (73), the slide plate (73) moves forward and backward on the longitudinal slide rail, a transverse driving motor (79) is fixedly connected to a mounting base provided on the driving motor 5 (71), a transverse slide plate (75) is provided at the output end of the transverse driving motor (79), the transverse slide plate (75) is provided with a longitudinal slide rail, a servo motor (76) is provided on the other side of the mounting base, a driving gear is provided at the output end of the servo motor (76), a relatively movable guide rack (74) is provided on the driving gear, and a clamping claw (78) is elastically hinged on the base of the servo motor (76) through a second tension spring (77).

7. A fully automatic dry fluorescent immunoassay device according to claim 6, characterized in that: The card placing mechanism (5) comprises a plurality of lower card boxes arranged at equal distances, wherein an elastic lifting plate is arranged at the bottom of the lower card box, and the top end of the elastic lifting plate is located on one side of the card pushing plate path, and is used to support the standard card below.

8. A fully automatic dry fluorescent immunoassay device according to claim 7, characterized in that: It also includes a computer control terminal, which is communicatively connected to a main control board, and the main control board includes: MCU1, MCU2 and MCU3, wherein: MCU1 is communicatively connected with the card pushing assembly (6), the incubation platform (4), the barcode scanner (68), the detection module (8) and the second card clamping manipulator device (7); MCU2 is connected to group a and group b of sample adding modules; The MCU3 is communicatively connected to a capping robot device (10) and a barcode scanner A.

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