OCT (optical coherence tomography) indicating turntable

Abstract

The utility model provides an OCT (Optical Coherence Tomography) indicating turntable which comprises a turntable, a connecting structure and a pointer component, the turntable has a scale surface. The connecting structure is arranged on the end face of the side, opposite to the scale face, of the rotary table, and the rotary table is coaxially connected with a focusing screw of the OCT equipment through the connecting structure. The pointer assembly comprises a pointer and a lifting seat, the pointer is arranged at the top of the lifting seat, the tip of the pointer extends to the edge of the scale surface, and the extension direction of the pointer is parallel to the scale lines of the scale surface. According to the OCT equipment focusing device, the pointer assembly can be flexibly installed on a focusing screw of any model of OCT equipment through a connecting structure, similarly, the pointer assembly can be flexibly placed at the corresponding position where the needle point is parallel to the scale line of the scale face, the probe moving distance of the OCT equipment can be accurately measured in an auxiliary mode, installation is convenient, the manufacturing cost is low, and wide popularization is facilitated.

Description

Technical Field

[0001] The utility model relates to the technical field of ophthalmic medical instruments, in particular to an OCT indicating turntable. Background Art

[0002] At present, in myopia research, optical coherence tomography (OCT) is mainly used as an auxiliary tool to measure the axial length and lens thickness of small animal models. For example, mice have become an animal model that has attracted much attention in the study of the mechanism of myopia because they are widely used in disease research, especially genetic research.

[0003] In the prior art, the axial length of the eye of a living mouse is mainly measured by optical coherence tomography auxiliary tools. The basic principle is to use a light beam emitted by a low-coherence light source to irradiate the target tissue or sample. This light beam is reflected back at different depths of the tissue, and the reflected light interferes with the light in the reference light path. By measuring the time delay of these reflected lights (i.e., the ratio of the distance traveled by the light wave to its speed in the tissue), OCT can non-invasively obtain the longitudinal structural information inside the tissue. The relationship between time delay and spatial distance can be expressed by the following formula: Δd = v × Δt, where Δt is the time delay of the light wave, Δd is the distance traveled by the light wave during this time, and v is the speed of the light wave in the tissue. The speed of light in the tissue is the ratio of the speed of light in a vacuum to the refractive index of the tissue. Therefore, when measuring the physical thickness of the tissue, it is necessary to know or assume the refractive index of the measured tissue. OCT can obtain the optical distance by continuously measuring the longitudinal distance at different transverse positions, which is divided by the refractive index of the measured tissue to obtain the physical distance.

[0004] However, due to the limitation of focal length, conventional OCT can only image and measure the cross-section of the eyeball at a shorter optical distance, and fails to cover the comprehensive measurement of the eye axis. Specifically, the measurement of the axial length is the length of the anteroposterior diameter of the mouse eye axis, which is the sum of a series of sub-lengths, including corneal thickness, anterior chamber depth, lens thickness, vitreous cavity depth and retinal thickness. Conventional OCT can only measure the shorter components of the eye axis, such as corneal thickness, anterior chamber depth, vitreous cavity depth and retinal thickness, but cannot measure the longer components of the eye axis, such as lens thickness, and therefore cannot know the full axial length of the mouse eye. To solve this problem, some researchers have tried to use stepper motors combined with OCT for measurement. The principle is to connect the stepper motor to the scanning probe, so that the axial movement distance between the scanning probe and the stepper motor group is the same. When the scanning probe scans the front and back surfaces of the mouse eye, the distance recorded by the stepper motor is the probe movement distance, and then the mouse eye axis length is calculated. Due to the wide variety of types and models of OCT devices, specific stepper motors need to be equipped according to the OCT device. Stepper motors are expensive and complex to install, and have not been promoted in ophthalmic research. Utility Model Content

[0005] Therefore, the technical problem to be solved by the utility model is to overcome the defects in the prior art that the OCT device moving distance measurement requires a specific stepper motor, which is costly and complex to install, and is not conducive to wide promotion, thereby providing an OCT indicator dial.

[0006] In order to solve the above problems, the utility model provides an OCT indicating turntable, comprising: a turntable having a scale surface; a connecting structure, arranged on the end surface of the turntable on the opposite side of the scale surface, and the turntable is coaxially connected to the focusing screw of the OCT device through the connecting structure; a pointer assembly, comprising a pointer and a lifting seat, the pointer is arranged on the top of the lifting seat, the tip of the pointer extends from the edge of the scale surface, and the extension direction of the pointer is parallel to the scale lines of the scale surface.

[0007] Optionally, the focusing screw is a fine focusing screw, and the turntable rotates synchronously with the fine focusing screw.

[0008] Optionally, the connection structure includes: a first clamping arm and a second clamping arm, the first clamping arm and the second clamping arm are connected to the end surface of the turntable opposite to the scale surface at an interval, and the first clamping arm and the second clamping arm are suitable for clamping on the focusing screw.

[0009] Optionally, the first clamp arm and the second clamp arm have a telescopic structure, and the telescopic structure is suitable for adjusting the length of the first clamp arm and the second clamp arm.

[0010] Optionally, the lifting seat includes a first lifting column, a second lifting column and a third lifting column, and the first lifting column, the second lifting column and the third lifting column are coaxially provided with a pinhole, a first through hole and a second through hole respectively, the pointer is arranged on the first lifting column through the pinhole, the first lifting column is movably arranged on the second lifting column through the first through hole, and the second lifting column is movably arranged on the third lifting column through the second through hole.

[0011] Optionally, the first lifting column, the second lifting column and the third lifting column are cylindrical or square column-shaped, and the cross-sectional shapes of the first through hole and the second through hole correspond to the outer edge shapes of the first lifting column and the second lifting column, respectively.

[0012] Optionally, a connecting piece is provided at the bottom of the lifting seat, and the lifting seat is installed on a frame of the OCT device through the connecting piece.

[0013] Optionally, the lifting seat is arranged directly below the turntable, and the extending direction of the pointer is parallel to the center line of the turntable in the height direction.

[0014] Optionally, the graduation value of the scale surface is 1 degree.

[0015] Optionally, a circular opening is provided on the turntable.

[0016] The utility model has the following advantages:

[0017] The OCT indicating turntable provided by the utility model comprises a turntable, a connecting structure and a pointer component.

[0018] The turntable has a scale surface. A connection structure is arranged on the end surface of the turntable on the opposite side of the scale surface, and the turntable is coaxially connected to the focusing screw of the OCT device through the connection structure. The pointer assembly includes a pointer and a lifting seat, the pointer is arranged on the top of the lifting seat, the tip of the pointer extends to the edge of the scale surface, and the extension direction of the pointer is parallel to the scale line of the scale surface.

[0019] When using the OCT device for measurement, the focusing screw can be rotated to drive the probe of the OCT device to move closer to or away from the mouse eyeball. The turntable and the focusing screw rotate synchronously, and the scale value indicated by the pointer is recorded before and after the rotation to facilitate the subsequent calculation of the probe movement distance. The probe movement distance is the mouse eye axis length. The above OCT indicator turntable can be flexibly installed on the focusing screw of any model of OCT equipment through the connection structure. Similarly, the pointer assembly can also be flexibly placed in the corresponding position where the needle tip is parallel to the scale line of the scale surface, which can accurately assist in measuring the probe movement distance of the OCT device. It is easy to install and has a low manufacturing cost, which is conducive to wide promotion. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the specific implementation methods of the utility model or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0021] Figure 1 A schematic diagram of the structure of the OCT indicator dial in this embodiment is shown;

[0022] Figure 2 for Figure 1 Axonometric view of the middle OCT indicator dial;

[0023] Figure 3 for Figure 1 A schematic diagram of the structure of the OCT indicator turntable from a top-down perspective;

[0024] Figure 4 for Figure 1A schematic diagram of the structure of the side view angle of the OCT indicator turntable;

[0025] Description of reference numerals:

[0026] 1. Turntable; 11. Circular opening; 21. First clamping arm; 22. Second clamping arm; 23. Connecting seat; 31. Pointer; 32. Lifting seat; 321. First lifting column; 322. Second lifting column; 323. Third lifting column; 5. Rack. DETAILED DESCRIPTION

[0027] The technical solution of the utility model will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0028] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0029] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0030] In addition, the technical features involved in the different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.

[0031] like Figure 1 , Figure 2 and Figure 3 As shown, in this embodiment, an OCT indicating dial is provided, including a dial 1, a connecting structure and a pointer assembly.

[0032] The rotating disk 1 has a scale surface, and the graduation value of the scale surface is 1 degree.

[0033] The connection structure is arranged on the end surface of the turntable 1 on the opposite side of the scale surface, and the turntable 1 is coaxially connected to the focusing screw 4 of the OCT device through the connection structure. When the focusing screw rotates, the turntable 1 can be driven to rotate.

[0034] The pointer assembly includes a pointer 31 and a lifting seat 32. The pointer 31 is arranged on the top of the lifting seat 32. The tip of the pointer 31 extends to the edge of the scale surface, and the extension direction of the pointer 31 is parallel to the scale line of the scale surface. The tip of the pointer 31 is close to the edge of the scale surface and is used to indicate the scale of the turntable. In this embodiment, it is used to record the scale change of the probe of the OCT device before and after the movement, so as to calculate the moving distance of the probe.

[0035] When using the OCT device for measurement, the focusing screw 4 can be rotated to drive the probe of the OCT device to move closer to or away from the mouse eyeball. The turntable 1 rotates synchronously with the focusing screw 4, and the scale value indicated by the pointer is recorded before and after the rotation, so as to facilitate the subsequent calculation of the probe movement distance. The probe movement distance is the mouse eye axis length. The above OCT indicator turntable can be flexibly installed on the focusing screw of any model of OCT equipment through the connection structure. Similarly, the pointer assembly can also be flexibly placed in the corresponding position where the needle tip is parallel to the scale line of the scale surface, which can accurately assist in measuring the probe movement distance of the OCT device. It is easy to install and has a low manufacturing cost, which is conducive to wide promotion.

[0036] It should be noted that after the OCT indicator dial provided in this embodiment is installed on the focusing screw of the OCT device, calibration is required. The calibration method is as follows: move the scanning probe 10 cm five times, record the five rotation degrees of the dial and calculate the average rotation degree of the five times. The optical distance represented by each degree change = 10 cm / average rotation degree. This facilitates the subsequent more accurate calculation of the distance moved by the probe during the experiment through the rotation degree. For example, a 1-degree rotation of the dial can correspond to a 3nm optical distance.

[0037] After the calibration is completed, the axial length of the mouse can be measured by the following steps:

[0038] Step 1: Fix the anesthetized mouse on the three-dimensional experimental table.

[0039] Step 2: Use mydriatic to dilate the mouse's pupils.

[0040] Step 3: Install the front lens on the lens of the OCT instrument and adjust the three-dimensional test platform so that the mouse eyeball is located directly in front of the front lens.

[0041] Step 4: To facilitate observation and accurate positioning of the reflective interface of each ocular tissue structure on the OCT two-dimensional image, a green crosshair is set in the center of the OCT image. The moving scanning probe continuously observes the reflected light from the surface of the cornea, lens, and retina appearing and tangent to the horizontal line of the crosshair, indicating that the scanning beam enters the eyeball perpendicularly along the direction of the eye axis.

[0042] Step 5: When rotating the fine focusing screw so that each surface is tangent to the horizontal line, record the corresponding turntable angle of this position. The recorded angle values ​​include the anterior and posterior surfaces of the cornea, the anterior and posterior surfaces of the lens, the retinal nerve fiber layer and the pigment epithelium (RPE). The thickness of each parameter of the axial length can be calculated by the difference between the corresponding values ​​of each two interfaces. That is, the anterior chamber depth is the difference between the values ​​of the posterior surface of the cornea and the anterior surface of the lens. The lens thickness is the difference between the values ​​of the anterior and posterior surfaces of the lens. The vitreous cavity depth is the difference between the values ​​of the posterior surface of the lens and the retinal nerve fiber layer. The axial length is the difference between the values ​​of the anterior surface of the cornea and the retinal nerve fiber layer. Since the retina and cornea can be imaged at the same focal length, all thicknesses are measured by analyzing the OCT corneal image with software.

[0043] Step 6: Convert the recorded value (optical distance) to the actual value (physical distance). To convert it to physical distance, it should be divided by the refractive index of each tissue structure. The refractive index of the cornea is 1.4015, the anterior chamber is 1.3336, the vitreous body is 1.3329, and the average axial length is 1.3341.

[0044] The axial length of the mouse eye can be obtained through the above steps.

[0045] like Figure 1 As shown, in this embodiment, a circular opening 11 is provided on the turntable 1. The circular opening 11 can facilitate the rocker of the focus screw 4 to pass through, and the operator can drive the focus screw to rotate through the rocker.

[0046] like Figure 3 As shown, in this embodiment, the focusing screw 4 is a fine focusing screw, and the turntable 1 rotates synchronously with the fine focusing screw.

[0047] like Figure 2 and Figure 3 As shown, in this embodiment, the connection structure includes: a first clamp arm 21 and a second clamp arm 22, the first clamp arm 21 and the second clamp arm 22 are connected to the end surface of the turntable 1 opposite to the scale surface at intervals, and the first clamp arm 21 and the second clamp arm 22 are suitable for clamping on the focus screw 4. The edges of the first clamp arm 21 and the second clamp arm 22 can be provided with a clamping groove, and the first clamp arm 21 and the second clamp arm 22 are symmetrically arranged with the center line of the turntable 1 as the symmetry axis, and the openings of the two clamping grooves are arranged facing each other, and the two clamping grooves are clamped on the outer edge of the focus screw, so that the turntable 1 can rotate synchronously with the focus screw.

[0048] like Figure 2 , Figure 3 and Figure 4 As shown, in a specific implementation of this embodiment, the connection structure also includes a connection seat 23, one end of which is connected to the center of the end face of the turntable 1 and has a through hole with the same radial direction as the circular opening 11, and the rocker can pass through the through hole and the circular opening 11 in sequence, and then extend from one side of the scale surface. The connection seat 23 has a first slot and a second slot opened in opposite directions, and the first clamp arm 21 and the second clamp arm 22 are respectively installed on the first slot and the second slot through the first elastic member and the second elastic member, so that the first clamp arm 21 can partially extend into the first slot and move in the first slot, and the second clamp arm 22 can partially extend into the second slot and move in the first slot. The first clamp arm 21 and the second clamp arm 22 can move in a direction away from each other to increase the distance between the two clamping slots. After being aligned with the position of the focus screw, the force applied to the first clamp arm 21 and the second clamp arm 22 can be cancelled, and the first clamp arm 21 and the second clamp arm 22 perform a reset movement in a direction close to each other under the action of the first elastic member and the second elastic member, so that the two clamping slots can be engaged with the outer edge of the focus screw. The user can easily install the turntable 1 on the focusing screw, which simplifies the installation difficulty.

[0049] In this embodiment, the first clamp arm 21 and the second clamp arm 22 have a telescopic structure, and the telescopic structure is suitable for adjusting the length of the first clamp arm 21 and the second clamp arm 22. Specifically, the thickness of the focusing screw may be different, and adjusting the length of the first clamp arm 21 and the second clamp arm 22 by the telescopic structure is conducive to adapting to focusing screws of different thicknesses.

[0050] For example, the openings of the clamping slots of the first clamping arm 21 and the second clamping arm 22 can be adjusted to accommodate focusing screws of different thicknesses.

[0051] like Figure 1 and Figure 2 As shown, in this embodiment, the lifting seat 32 includes a first lifting column 321, a second lifting column 322 and a third lifting column 323. The first lifting column 321, the second lifting column 322 and the third lifting column 323 are coaxially provided with a pinhole, a first through hole and a second through hole, respectively. The pointer 31 is provided on the first lifting column 321 through the pinhole. The first lifting column 321 is movably provided on the second lifting column 322 through the first through hole. The second lifting column 322 is movably provided on the third lifting column 323 through the second through hole. The radial dimensions of the first through hole and the second through hole can be set according to the radial dimensions of the first lifting column 321 and the second lifting column 322, so that the first lifting column 321 can avoid relative displacement with the second lifting column 322 by friction in the absence of external force. Similarly, the second lifting column 322 can also avoid relative displacement with the third lifting column by friction.

[0052] The arrangement of the first lifting column 321 , the second lifting column 322 and the third lifting column 323 can flexibly adjust the height of the pointer 31 , so as to adapt to the distance between the rack 5 and the focusing screw of different models of OCT.

[0053] In this embodiment, the first lifting column 321, the second lifting column 322 and the third lifting column 323 are cylindrical or square column-shaped, and the cross-sectional shapes of the first through hole and the second through hole correspond to the outer edge shapes of the first lifting column and the second lifting column, respectively.

[0054] In this embodiment, a connector is provided at the bottom of the lifting seat 32, and the lifting seat 32 is mounted on the frame 5 of the OCT device through the connector. For example, the connector can be a suction cup, or a magnetic structure or other structure that can be used to fix the position of the lifting seat.

[0055] In this embodiment, the lifting seat 32 is arranged directly below the turntable 1, and the extending direction of the pointer is parallel to the center line of the turntable 1 in the height direction. Such an arrangement is conducive to directly observing the scale indication, and of course, the placement position of the lifting seat 32 can also be reasonably set according to the structure of the OCT device to ensure that the tip of the pointer is parallel to the scale line.

[0056] Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived therefrom are still within the scope of protection of the invention.

Claims

1. An OCT indicator dial, characterized in that: include: A rotating disk (1) having a graduated surface; A connection structure is arranged on the end surface of the turntable (1) on the side opposite to the scale surface, and the turntable (1) is coaxially connected to the focusing screw of the OCT device through the connection structure; A pointer (31) assembly comprises a pointer (31) and a lifting seat (32), wherein the pointer (31) is arranged on the top of the lifting seat (32), the tip of the pointer (31) extends to the edge of the scale surface, and the extension direction of the pointer (31) is parallel to the scale lines of the scale surface.

2. The OCT indicator dial according to claim 1, characterized in that: The focusing screw is a fine focusing screw, and the rotating disk (1) rotates synchronously with the fine focusing screw.

3. The OCT indicator dial according to any one of claims 1 to 2, characterized in that: The connection structure comprises: a first clamping arm (21) and a second clamping arm (22); the first clamping arm (21) and the second clamping arm (22) are connected to the end surface of the turntable (1) opposite to the scale surface at intervals; the first clamping arm (21) and the second clamping arm (22) are suitable for clamping on the focusing screw.

4. The OCT indicator dial according to claim 3, characterized in that: The first clamping arm (21) and the second clamping arm (22) have a telescopic structure, and the telescopic structure is suitable for adjusting the length of the first clamping arm (21) and the second clamping arm (22).

5. The OCT indicator dial according to claim 1, characterized in that: The lifting seat (32) comprises a first lifting column (321), a second lifting column (322) and a third lifting column (323); a pinhole, a first through hole and a second through hole are coaxially arranged on the first lifting column (321), the second lifting column (322) and the third lifting column (323), respectively; the pointer (31) is arranged on the first lifting column (321) through the pinhole; the first lifting column (321) is movably arranged on the second lifting column (322) through the first through hole; and the second lifting column (322) is movably arranged on the third lifting column (323) through the second through hole.

6. The OCT indicator dial according to claim 5, characterized in that: The first lifting column (321), the second lifting column (322) and the third lifting column (323) are cylindrical or square column-shaped, and the cross-sectional shapes of the first through hole and the second through hole correspond to the outer edge shapes of the first lifting column (321) and the second lifting column (322), respectively.

7. The OCT indicator dial according to claim 1, characterized in that: A connecting piece is provided at the bottom of the lifting seat (32), and the lifting seat (32) is mounted on a frame (5) of the OCT equipment via the connecting piece.

8. The OCT indicator dial according to claim 1, characterized in that: The lifting seat (32) is arranged directly below the turntable (1), and the extending direction of the pointer (31) is parallel to the center line of the turntable (1) in the height direction.

9. The OCT indicator dial according to claim 1, characterized in that: The graduation value of the scale surface is 1 degree.

10. The OCT indicator dial according to claim 1, characterized in that: The rotating disk (1) is provided with a circular opening (11).

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