Rat cerebrospinal fluid extraction device

Abstract

The utility model relates to the technical field of experimental extraction devices, in particular to a mouse cerebrospinal fluid extraction device, which comprises a supporting part, a connecting part and a connecting part, the supporting part consists of a vertical plate and a transverse plate, the vertical plate is fixedly connected to the upper surface of the transverse plate, so that the whole supporting part is L-shaped, and a groove for placing a mouse head is formed in the vertical plate; the mouse body fixing part is fixedly arranged on the upper surface of the transverse plate and comprises a supporting plate and a bandage; the hand placing part is movably arranged on the upper surface of the transverse plate and is used for placing the hand of a sampling person; the mouse head fixing part is arranged on the vertical plate and comprises two clamping plates which move relatively and a driving unit, the whole body of a mouse is fixed through the mouse body fixing part and the mouse head fixing part, the hand placing part is moved to the position above the mouse body, and the hand of a sampling person is placed through the hand placing part; the situation that the hand of a sampling person shakes when the spines of the mouse are extracted, and the extraction efficiency is affected is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of experimental extraction devices, in particular to a mouse cerebrospinal fluid extraction device. Background Art

[0002] Cerebrospinal fluid is a colorless, transparent liquid that fills the ventricles, subarachnoid space, and central canal of the spinal cord. It mainly protects, supports, and nourishes the brain and spinal cord. Clinical and basic research such as neuropharmacology and nervous system diseases often requires the detection of changes in cerebrospinal fluid composition. Mice are the most commonly used experimental animals in cerebrospinal fluid research, but the content of their cerebrospinal fluid is very low, and it is very difficult to extract.

[0003] After searching, a mouse head fixing device for extracting mouse cerebrospinal fluid is disclosed in the Chinese Utility Model Patent Library, and the application number is: CN201620712191.9, because it has two mouse ear fixers that are movably connected to the two sides of the bracket unit, and the mouse ear fixer has a mouse ear fixing part for clamping the mouse ear; a mouse mouth fixer that is movably connected to the bracket unit, and the mouse mouth fixer has a mouse mouth fixing part that is vertically arranged with the mouse ear fixing part; and an extraction needle holder that is movably connected to one side of the bracket unit, located on the other side of the mouse mouth fixer relative to the mouse ear fixing part, and the extraction needle holder has an extraction needle bracket that is vertically arranged with the mouse ear fixing part, and is used to place the extraction needle. Therefore, the mouse head fixing device for extracting mouse cerebrospinal fluid provided by the utility model can not only fix the mouse head, but also provide fixed support for the extraction needle, so that the operator can accurately quantify the needle insertion depth and needle insertion angle during the extraction process, and successfully complete the operation of extracting mouse cerebrospinal fluid.

[0004] However, in the above patent, during the process of extracting rat cerebrospinal fluid, the hands of the extractor are in a suspended state, and the hands will inevitably shake during the process, which affects the efficiency of extracting rat cerebrospinal fluid. Utility Model Content

[0005] In order to achieve the above objectives, the present invention is implemented through the following technical solutions:

[0006] A mouse cerebrospinal fluid extraction device, comprising:

[0007] The support part is composed of a vertical plate and a horizontal plate, wherein the vertical plate is fixedly connected to the upper surface of the horizontal plate so that the support part is arranged in an L shape as a whole, and a groove for placing a mouse head is provided on the vertical plate;

[0008] A mouse body fixing part, which is fixedly arranged on the upper surface of the horizontal board, comprises a supporting plate and a binding belt;

[0009] A hand placement part, which is movably arranged on the upper surface of the horizontal plate and is used for placing the hands of the sampling personnel;

[0010] The mouse head fixing part is arranged on the vertical plate, and comprises two relatively movable clamping plates and a driving unit, wherein the clamping plates relatively move under the action of the driving unit.

[0011] Preferably, both front and rear sides of the upper end of the support plate are fixedly connected to support rods, and the binding straps are movably arranged on the support rods.

[0012] Preferably, the driving unit includes a bidirectional screw rod, one end of which is rotatably connected to the vertical plate, and the other end of which rotates through the vertical plate and is rotatably connected to the rotating block. The outer surface of the bidirectional screw rod is symmetrically provided with internal thread blocks, and an L-shaped connecting rod is fixedly connected to the bottom of the internal thread block, and the other end of the connecting rod is fixedly connected to the clamping plate.

[0013] Preferably, the hand placement part includes a placement plate, a telescopic rod is symmetrically arranged at the bottom of the placement plate, a sliding sleeve is provided on the bottom end of the telescopic rod, a locking unit is arranged at the bottom of the telescopic rod, the telescopic rod is engaged with the sliding sleeve through the locking unit, a sliding block is arranged at the bottom of the sliding sleeve, and the outer surface of the sliding block is slidably connected to the cross plate.

[0014] Preferably, the locking unit includes a locking block, which is slidably arranged at the bottom of the telescopic rod, a spring is arranged at one end of the locking block, the other end of the spring is fixedly connected to the telescopic rod, and the outer surface of the sliding sleeve is provided with limiting holes evenly arranged up and down.

[0015] Preferably, a slide groove 1 is provided on the transverse plate, and the sliding block is slidably connected to the transverse plate via the slide groove 1.

[0016] Preferably, a second slide groove is provided on the vertical plate, and the connecting rod is arranged in the second slide groove.

[0017] The utility model provides a mouse cerebrospinal fluid extraction device, which has the following beneficial effects:

[0018] In the utility model, the whole body of the mouse is fixed by the mouse body fixing part and the mouse head fixing part, and the hand placing part is moved above the mouse body. The hand placing part is used to place the hands of the sampler, so as to avoid shaking of the hands of the sampler when extracting the spinal fluid of the mouse, which affects the extraction efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the overall structure of the mouse cerebrospinal fluid extraction device in the utility model;

[0020] Figure 2 This is a schematic diagram of the front structure of the mouse cerebrospinal fluid extraction device of the utility model;

[0021] Figure 3 For the utility model Figure 2Schematic diagram of the internal structure of AA.

[0022] In the figure:

[0023] 10-support part, 11-vertical plate, 12-horizontal plate, 13-slideway 1, 14-slideway 2;

[0024] 20-body fixing part, 21-binding strap, 22-support rod, 23-support plate;

[0025] 30-hand placement part, 31-placement plate, 32-telescopic rod, 33-block, 34-spring, 35-slider, 36-sliding sleeve, 37-limiting hole;

[0026] 40 - rat head fixing part, 41 - clamping plate, 42 - bidirectional screw rod, 43 - internal thread block, 44 - connecting rod, 45 - rotating block. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0028] See also Figure 1-3 The utility model provides a technical solution:

[0029] A mouse cerebrospinal fluid extraction device, comprising:

[0030] The support part 10 is composed of a vertical plate 11 and a horizontal plate 12. The vertical plate 11 is fixed to the upper surface of the horizontal plate 12, so that the support part 10 is arranged in an L shape as a whole, and a groove for placing a mouse head is opened on the vertical plate 11;

[0031] The mouse body fixing part 20 is fixedly arranged on the upper surface of the horizontal plate 12, and includes a support plate 23 and a strap 21. When the mouse is placed on the support plate 23, the mouse body is fixed by the strap 21;

[0032] The hand placement part 30 is movably arranged on the upper surface of the horizontal plate 12 and is used for placing the hands of the sampling personnel to avoid the sampling personnel's hands being suspended in the air, which affects the efficiency of spinal fluid extraction;

[0033] The mouse head fixing part 40 is arranged on the vertical plate 11, and includes two relatively movable clamping plates 41 and a driving unit. The clamping plates 41 relatively move under the action of the driving unit to clamp both sides of the mouse's head, thereby clamping and fixing the mouse's head.

[0034] In the above, the whole body of the mouse is fixed by the mouse body fixing part 20 and the mouse head fixing part 40, and the hand placing part 30 is moved above the mouse body. The hand placing part 30 is used to place the hands of the sampler, so as to avoid shaking of the hands of the sampler when extracting the spinal fluid of the mouse, thereby affecting the extraction efficiency.

[0035] Please continue reading Figure 2 The front and rear sides of the upper end of the support plate 23 are fixedly connected to the support rod 22, and the strap 21 is movably arranged on the support rod 22. Preferably, the strap 21 is an elastic strap, so that the strap 21 can move on the support rod 22 according to the size of the mouse and fix the body part of the mouse through the strap 21.

[0036] Please continue reading Figure 1 The driving unit includes a bidirectional screw rod 42, one end of which is rotatably connected to the vertical plate 11, and the other end of the bidirectional screw rod 42 rotates through the vertical plate 11 and is rotatably connected to the rotating block 45. The outer surface of the bidirectional screw rod 42 is symmetrically provided with an internal thread block 43, and the bottom of the internal thread block 43 is fixedly connected with an L-shaped connecting rod 44, and the other end of the connecting rod 44 is fixedly connected to the clamping plate 41. In this way, the internal thread block 43 is driven to move relative to the setting of the bidirectional screw rod 42, and then the connecting rod 44 is driven to move relative to the clamping plate 41, so as to achieve the clamping and fixation of the mouse head. At the same time, in order to avoid hurting the mouse during the clamping process, the clamping plate 41 is a flexible clamping plate.

[0037] Please continue reading Figure 3 The hand placement part 30 includes a placement plate 31, and a telescopic rod 32 is symmetrically arranged at the bottom of the placement plate 31. A sliding sleeve 36 is sleeved on the bottom end of the telescopic rod 32, and a locking unit is arranged at the bottom of the telescopic rod 32. The telescopic rod 32 is engaged with the sliding sleeve 36 through the locking unit. A sliding block 35 is arranged at the bottom of the sliding sleeve 36, and the outer surface of the sliding block 35 is slidably connected to the horizontal plate 12. In this way, the hand of the extraction personnel is placed by the placement plate 31, and the sliding block 35 is moved on the horizontal plate 12 to realize the support and movement of the extraction personnel, thereby improving the efficiency of spinal fluid extraction.

[0038] Please continue reading Figure 3 The engaging unit includes a card block 33, which is slidably arranged at the bottom of the telescopic rod 32, and a spring 34 is arranged at one end of the card block 33, and the other end of the spring 34 is fixedly connected to the telescopic rod 32, and the outer surface of the sliding sleeve 36 is provided with limiting holes 37 which are evenly arranged up and down. In this way, the height adjustment of the telescopic rod 32 is achieved through the cooperation of the card block 33, the spring 34 and the limiting holes 37, so that the height of the placing plate 31 can be adjusted according to the height of the mouse body to avoid collision.

[0039] Please continue reading Figure 1 The horizontal plate 12 is provided with a slide groove 14, and the slider 35 is slidably connected to the horizontal plate 12 through the slide groove 14 to guide the slider 35 and prevent the slider 35 from deflecting when moving.

[0040] Please continue reading Figure 1 The vertical plate 11 is provided with a second slide groove 13, and the connecting rod 44 is arranged in the second slide groove 13 to guide the connecting rod 44 and prevent the connecting rod 44 from rotating when the internal thread block 43 rotates, thereby affecting its clamping efficiency.

[0041] Working principle: When in use, place the mouse on the tray 23, first place the mouse's head in the groove on the vertical plate 11, rotate the rotating block 45, drive the two internal thread blocks 42 to move relative to each other, and then drive the two clamping plates 41 to move relative to each other, so as to clamp and fix the mouse's head. Then, fix the mouse's body part by the strap 21, so that the mouse is in a fixed state. At this time, push the slider 35 to move the placement plate 31 to a reasonable position on the upper side of the mouse's body. The extraction personnel places their hands on the placement plate 31 to achieve extraction, thereby avoiding shaking of the sampling personnel's hands when extracting the mouse's spinal fluid, which affects the extraction efficiency.

[0042] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A mouse cerebrospinal fluid extraction device, characterized in that: include: The support part is composed of a vertical plate and a horizontal plate, wherein the vertical plate is fixedly connected to the upper surface of the horizontal plate so that the support part is arranged in an L shape as a whole, and a groove for placing a mouse head is provided on the vertical plate; A mouse body fixing part, which is fixedly arranged on the upper surface of the horizontal board, comprises a supporting plate and a binding belt; A hand placement part, which is movably arranged on the upper surface of the horizontal plate and is used for placing the hands of the sampling personnel; The mouse head fixing part is arranged on the vertical plate, and comprises two relatively movable clamping plates and a driving unit, wherein the clamping plates relatively move under the action of the driving unit.

2. A rat cerebrospinal fluid extraction device as claimed in claim 1, characterized in that: The front and rear sides of the upper end of the support plate are both fixedly connected with support rods, and the binding belt is movably arranged on the support rods.

3. A rat cerebrospinal fluid extraction device as claimed in claim 1, characterized in that: The driving unit includes a bidirectional screw rod, one end of which is rotatably connected to the vertical plate, and the other end of which rotates through the vertical plate and is rotatably connected to the rotating block. The outer surface of the bidirectional screw rod is symmetrically provided with internal thread blocks, and an L-shaped connecting rod is fixedly connected to the bottom of the internal thread block, and the other end of the connecting rod is fixedly connected to the clamping plate.

4. A rat cerebrospinal fluid extraction device as claimed in claim 1, characterized in that: The hand placement part includes a placement plate, a telescopic rod is symmetrically arranged at the bottom of the placement plate, a sliding sleeve is sleeved on the bottom end of the telescopic rod, a clamping unit is arranged at the bottom of the telescopic rod, the telescopic rod is clamped with the sliding sleeve through the clamping unit, a sliding block is arranged at the bottom of the sliding sleeve, and the outer surface of the sliding block is slidably connected to the cross plate.

5. A rat cerebrospinal fluid extraction device as claimed in claim 4, characterized in that: The engaging unit comprises a card block, which is slidably arranged at the bottom of the telescopic rod, one end of the card block is provided with a spring, the other end of the spring is fixedly connected to the telescopic rod, and the outer surface of the sliding sleeve is provided with limiting holes evenly arranged up and down.

6. A rat cerebrospinal fluid extraction device as claimed in claim 5, characterized in that: The transverse plate is provided with a slide groove 1, and the sliding block is slidably connected with the transverse plate via the slide groove 1.

7. A rat cerebrospinal fluid extraction device as claimed in claim 3, characterized in that: The vertical plate is provided with a second slide groove, and the connecting rod is arranged in the second slide groove.

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