Device for producing 2-chloronicotinonitrile through continuous chlorination reaction of cyanopyridine nitrogen oxide

Abstract

The utility model discloses a device for producing 2-chloronicotinonitrile through cyanopyridine nitrogen oxide chlorination continuous reaction. The device comprises a mixing kettle, a feeding pump A, a display screen, and a material storage tank, a feeding pump B, a dynamic tubular reactor, a continuous tubular reactor and a material receiving tank which are sequentially connected together, the mixing kettle, the feeding pump A and the dynamic tubular reactor are connected in sequence; the dynamic tubular reactor and the continuous tubular reactor are connected with the jacket heat exchanger, and the dynamic tubular reactor and the continuous tubular reactor are connected with the temperature sensor and the pressure sensor; the display screen is electrically connected with the temperature sensor and the pressure sensor. The dynamic tubular reactor and the continuous tubular reactor are matched to realize the production of 2-chloronicotinonitrile, the reaction process is simple to operate, convenient to control and high in safety, the reaction speed in the production process is high, the yield of 2-chloronicotinonitrile is high, the utilization rate of phosphorus oxychloride can be improved, the generation of by-products is reduced, and the production cost is reduced. Meanwhile, continuous reaction can be realized in the production process.

Description

Technical Field

[0001] The utility model relates to the technical field of 2-chloronicotinonitrile production devices, in particular to a device for producing 2-chloronicotinonitrile by continuous chlorination reaction of cyanopyridine nitrogen oxide. Background Art

[0002] 2-Chloronicotinonitrile is mainly used in the synthesis of pharmaceutical intermediates and pesticide intermediates, and can be used to produce a variety of anti-tumor drugs and pesticides. In addition, it can also be used to synthesize dyes, fragrances, liquid crystals and other materials.

[0003] At present, there are many ways to synthesize 2-chloronicotinonitrile in China. Usually, 2-chloro-3-trichloromethylpyridine is used as a raw material, reacted with a large amount of phosphoric acid, hydrochloric acid, etc., and hydrolyzed to synthesize 2-chloronicotinonitrile; or nicotinic acid is used as a raw material, oxidized with hydrogen peroxide to obtain N-nicotinic acid oxide, and then chlorinated with phosphorus oxychloride and phosphorus pentachloride to synthesize 2-chloronicotinonitrile. At present, these reactions are mostly carried out in kettle reactions, which are difficult to operate. Improper operation may lead to safety accidents or poor product quality. In addition, chlorination reactions usually require high temperature, high pressure and high concentration conditions, so a large amount of energy is required to maintain the reaction, resulting in high energy consumption. Utility Model Content

[0004] In view of the above-mentioned shortcomings of the axe reaction, such as the difficulty in operation, difficulty in ensuring product quality, potential safety hazards, and high production energy consumption, the utility model provides a device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide, which is simple and safe to operate, can ensure product quality and reduce production energy consumption.

[0005] To achieve the above purpose, the technical solution of the utility model is as follows:

[0006] A device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide comprises a mixing kettle, a feed pump A, a display screen, and a storage tank, a feed pump B, a dynamic tubular reactor, a continuous tubular reactor and a receiving tank connected in sequence; the mixing kettle is connected to the feed pump A, and the feed pump is connected to the dynamic tubular reactor; the outer peripheries of the dynamic tubular reactor and the continuous tubular reactor are respectively provided with jacketed heat exchangers, and the dynamic tubular reactor and the continuous tubular reactor are provided with temperature sensors and pressure sensors; the display screen is electrically connected to the temperature sensor and the pressure sensor, respectively.

[0007] The feed port on the side of the dynamic tubular reactor is connected to a temperature sensor, the discharge port is connected to a temperature sensor and a pressure sensor, the feed port of the continuous tubular reactor is connected to a pressure sensor, and temperature sensors are installed at the front and rear sections of the interior.

[0008] Furthermore, the side of the dynamic tubular reactor is provided with a side feed port and a side discharge port, and the top is also provided with a plurality of top feed ports, wherein the side feed port is connected to the feed pump B, and the top feed port is connected to the feed pump A. The raw material formed by the mixture of cyanopyridine nitrogen oxide and phosphorus oxychloride in the mixing kettle is transmitted to the plurality of top feed ports through the cooperation of the feed pump A and the connection, and the triethylamine in the storage tank is transmitted to the dynamic tubular reactor through the cooperation of the feed pump B and the connection, and the raw material can be dispersed into the plurality of top feed ports of the dynamic tubular reactor, so that the substances in the dynamic tubular reactor can be mixed and reacted more fully, thereby improving the effect of the initial chlorination reaction and the subsequent product rate of 2-chloronicotinonitrile.

[0009] Furthermore, temperature sensors are provided between the feed pump A and the dynamic tubular reactor and between the feed pump B and the dynamic tubular reactor; the temperature sensors are electrically connected to display screens respectively. The staff can observe the production temperature at each position of the production process through the display screen, and can promptly discover the abnormal local temperature, which is convenient for production monitoring.

[0010] Furthermore, a sight glass is provided at the discharge port of the dynamic tubular reactor, which is made of high borosilicate glass and can facilitate the staff to observe the mixed materials at the outlet of the dynamic tubular reactor.

[0011] Furthermore, a pipeline mixer is provided between the dynamic tubular reactor and the continuous tubular reactor, the inlet end of the pipeline mixer is connected to the dynamic tubular reactor, and the outlet end is connected to the continuous tubular reactor. The pipeline mixer can evenly mix the preliminarily chlorinated mixture in the dynamic tubular reactor, which is convenient for the next step of production and processing.

[0012] Furthermore, a jacket heat exchanger is provided on the outer periphery of the pipeline mixer, and a plurality of mixing plates are provided inside the pipeline mixer; one end of the mixing plate is connected to the inner wall of the pipeline mixer and is inclined toward the outlet end of the pipeline mixer. The jacket heat exchanger is connected to the circulating water pipe of the factory, and the raw materials enter the pipeline mixer and are evenly mixed by the mixing plates, which is convenient for subsequent production and processing.

[0013] When the utility model is used, the steps are as follows:

[0014] Step 1: connect the jacket heat exchanger of the dynamic tubular reactor to the circulating water circuit of the factory, and connect the jacket heat exchanger of the continuous tubular reactor to the high-temperature steam pipeline of the factory; add the raw materials cyanopyridine nitrogen oxide and phosphorus oxychloride into the mixing kettle in a mass ratio of 1:6 for mixing and stirring, and then let the mixed raw materials stand. When the temperature of the raw materials drops below 16°C, they can be put into production and use; at the same time, add triethylamine into the storage tank;

[0015] Step 2: Pump the mixed raw materials in the mixing axe into the dynamic tubular reactor through the feed pump A; turn on the feed pump B, and the feed pump B pumps the triethylamine in the storage tank into the dynamic tubular reactor;

[0016] Step 3: The raw material is connected to the dynamic tubular reactor and undergoes a preliminary chlorination reaction with the added triethylamine. After the reaction starts, the values ​​of the temperature sensor and the pressure sensor connected to the dynamic tubular reactor are observed through the display screen. When the temperature of the dynamic tubular reactor is higher than 55°C, the jacket heat exchanger is turned on, and circulating water continuously flows into the jacket heat exchanger to cool the dynamic tubular reactor. When the temperature of the dynamic tubular reactor is lower than 45°C, the jacket heat exchanger is turned off to stop the heat exchange operation;

[0017] Step 4: The raw material formed by mixing cyanopyridine nitrogen oxide and phosphorus oxychloride and triethylamine are subjected to a preliminary chlorination reaction in a dynamic tubular reactor. The overall reaction time is 45 minutes, and the final mixture temperature is maintained at 50±5°C;

[0018] Step 5: The mixture formed by the reaction in the dynamic tubular reactor is transferred to the connecting reactor for further reaction, and the reaction is carried out in the continuous tubular reactor for about 45 minutes. During the reaction, the temperature sensor of the continuous tubular reactor is observed, and when the temperature is lower than 88° C., the jacket of the continuous tubular reactor is opened to heat the continuous tubular reactor with high-temperature steam, and when the temperature is higher than 92° C., the jacket of the continuous tubular reactor is closed to maintain the reaction temperature of the continuous tubular reactor at 88° C.-92° C.;

[0019] Step 6: The final product of the continuous tubular reactor is loaded into a receiving tank for storage.

[0020] Compared with the prior art, the utility model has the following advantages and beneficial effects:

[0021] 1. The utility model mainly realizes the production of 2-chloronicotinonitrile by cooperating a dynamic tubular reactor with a continuous tubular reactor. The production process adopts a tubular reaction, the reaction process is simple to operate, convenient to control and highly safe, and the raw materials flow at a certain flow rate in the tubular reactor, and a chlorination reaction occurs under suitable temperature and pressure conditions, which has the characteristics of good heat and mass transfer effect and fast reaction speed, high 2-chloronicotinonitrile product rate, and can improve the utilization rate of phosphorus oxychloride and reduce the generation of by-products. At the same time, the production process can realize continuous reaction; the jacket heat exchanger is matched with a temperature sensor or a pressure sensor, which is convenient for observing the temperature or pressure of the reaction, and can ensure production safety. At the same time, the jacket heat exchanger can effectively control the chlorination reaction temperature, which is convenient for controlling the reaction temperature.

[0022] 2. The utility model adopts a dynamic tubular reactor and a continuous tubular reactor for production, so that the material can flow more evenly in the tube, reducing the problem of local overheating; at the same time, the material flows to carry out chlorination reaction, which reduces production energy consumption while achieving high reaction efficiency, high product purity and high production safety; the setting of the sight glass makes it convenient for the staff to observe the material status during the production process; the pipeline mixer arranged between the dynamic tubular reactor and the continuous tubular reactor can make the preliminary chlorinated mixture in the dynamic tubular reactor be evenly mixed, which is convenient for the next step of production and processing of 2-chloronicotinonitrile. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 The utility model discloses a component connection relationship diagram of a device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide.

[0024] Figure 2 The utility model discloses a pipeline mixer for producing 2-chloronicotinonitrile by continuous chlorination reaction of cyanopyridine nitrogen oxide.

[0025] Figure ID:

[0026] Mixing kettle—1, storage tank—2, feed pump A—3, feed pump B—4, jacketed heat exchanger—5, dynamic tubular reactor—6, continuous tubular reactor—7, receiving tank—8, pipeline mixer—9, mixing plate—91, temperature sensor—10, pressure sensor—11. DETAILED DESCRIPTION

[0027] The utility model is further described below in conjunction with the accompanying drawings.

[0028] Embodiment 1: A device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide, comprising a mixing kettle 1, a feed pump A3, a display screen 13, and a storage tank 2, a feed pump B4, a dynamic tubular reactor 6, a continuous tubular reactor 7 and a receiving tank 8 connected in sequence; the mixing kettle 1 is connected to the feed pump A3, and the feed pump is connected to the dynamic tubular reactor 6; the outer peripheries of the dynamic tubular reactor 6 and the continuous tubular reactor 7 are respectively provided with jacketed heat exchangers 5, and the dynamic tubular reactor 6 and the continuous tubular reactor 7 are provided with temperature sensors 10 and pressure sensors 11; the display screen 13 is electrically connected to the temperature sensor 10 and the pressure sensor 11, respectively.

[0029] Among them, the feed port on the side of the dynamic tubular reactor 6 is connected to a temperature sensor 10, the discharge port is connected to a temperature sensor 10 and a pressure sensor 11, the feed port of the continuous tubular reactor 7 is connected to a pressure sensor 11, and temperature sensors 10 are installed at the front and rear sections inside.

[0030] Step 1: connect the jacket heat exchanger 5 of the dynamic tubular reactor 6 to the circulating water circuit of the factory, and connect the jacket heat exchanger 5 of the continuous tubular reactor 7 to the high-temperature steam pipeline of the factory; add the raw materials cyanopyridine nitrogen oxide and phosphorus oxychloride in a mass ratio of 1:6 into the mixing kettle 1 for mixing and stirring, and then let the mixed raw materials stand, and when the temperature of the raw materials drops below 16°C, they can be put into production and use; at the same time, add triethylamine into the storage tank 2;

[0031] Step 2: pump the mixed raw materials in the mixing axe into the dynamic tubular reactor 6 through the feed pump A3; turn on the feed pump B4, and the feed pump B4 pumps the triethylamine in the storage tank 2 into the dynamic tubular reactor 6;

[0032] Step 3: The raw material is connected to the dynamic tubular reactor 6 and undergoes a preliminary chlorination reaction with the added triethylamine. After the reaction starts, the values ​​of the temperature sensor 10 and the pressure sensor 11 connected to the dynamic tubular reactor 6 are observed through the display screen 13. When the temperature of the dynamic tubular reactor 6 is higher than 55° C., the jacket heat exchanger is turned on, and circulating water continuously flows into the jacket heat exchanger 5 to cool the dynamic tubular reactor 6. When the temperature of the dynamic tubular reactor 6 is lower than 45° C., the jacket heat exchanger 5 is turned off to stop the heat exchange operation;

[0033] Step 4: the raw material formed by mixing cyanopyridine nitrogen oxide and phosphorus oxychloride and triethylamine are subjected to a preliminary chlorination reaction in a dynamic tubular reactor 6, the overall reaction time is 45 minutes, and the final mixture temperature is maintained at 50±5°C;

[0034] Step 5: The mixture formed by the reaction in the dynamic tubular reactor 6 is transferred to the connecting reactor for further reaction, and the reaction is carried out in the continuous tubular reactor 7 for about 45 minutes. During the reaction, the temperature sensor 10 of the continuous tubular reactor 7 is observed. When the temperature is lower than 88° C., the jacket of the continuous tubular reactor 7 is opened to heat the continuous tubular reactor 7 with high-temperature steam. When the temperature is higher than 92° C., the jacket of the continuous tubular reactor 7 is closed to maintain the reaction temperature of the continuous tubular reactor 7 at 88° C.-92° C.;

[0035] Step 6: The final product of the continuous tubular reactor 7 is loaded into a receiving tank 8 for storage.

[0036] The utility model mainly realizes the production of 2-chloronicotinonitrile by cooperating with a dynamic tubular reactor 6 and a continuous tubular reactor 7. The production process adopts a tubular reaction, the reaction process is simple to operate, convenient to control and highly safe, and the raw materials flow at a certain flow rate in the tubular reactor, and a chlorination reaction occurs under suitable temperature and pressure conditions, which has the characteristics of good heat and mass transfer effect and fast reaction speed, high 2-chloronicotinonitrile product rate, and can improve the utilization rate of phosphorus oxychloride and reduce the generation of by-products. At the same time, the production process can realize continuous reaction; the jacket heat exchanger 5 is matched with a temperature sensor 10 or a pressure sensor, which is convenient for observing the temperature or pressure of the reaction, and can ensure production safety. At the same time, the jacket heat exchanger 5 can effectively control the chlorination reaction temperature, which is convenient for controlling the reaction temperature.

[0037] Embodiment 2: The difference from Embodiment 1 is that the side of the dynamic tubular reactor 6 is provided with a side feed port and a side discharge port, and the top is also provided with a plurality of top feed ports, wherein the side feed port is connected to the feed pump B4, and the top feed port is connected to the feed pump A3. The raw material formed by the mixture of cyanopyridine nitrogen oxide and phosphorus oxychloride in the mixing kettle 1 is transmitted to the plurality of top feed ports through the cooperation of the feed pump A3 and the connection, and the triethylamine in the storage tank 2 is transmitted to the dynamic tubular reactor 6 through the cooperation of the feed pump B4 and the connection, and the raw material can be dispersed into the plurality of top feed ports of the dynamic tubular reactor 6, so that the materials in the dynamic tubular reactor 6 can be mixed and reacted more fully, thereby improving the effect of the initial chlorination reaction and the subsequent product rate of 2-chloronicotinonitrile.

[0038] A sight glass is provided at the discharge port of the dynamic tubular reactor 6. The sight glass is made of high borosilicate glass, and the sight glass can facilitate the staff to observe the mixed materials at the outlet of the dynamic tubular reactor 6.

[0039] A pipeline mixer 9 is provided between the dynamic tubular reactor 6 and the continuous tubular reactor 7, wherein the inlet end of the pipeline mixer 9 is connected to the dynamic tubular reactor 6, and the outlet end of the pipeline mixer 9 is connected to the continuous tubular reactor 7. The pipeline mixer 9 can evenly mix the preliminarily chlorinated mixture in the dynamic tubular reactor 6, which is convenient for the next step of production and processing.

[0040] Embodiment 3: The difference from Embodiment 2 is that a temperature sensor 10 is provided between the feed pump A3 and the dynamic tubular reactor 6 and between the feed pump B4 and the dynamic tubular reactor 6; the temperature sensor 10 is electrically connected to a display screen 13. The staff can observe the production temperature at each position of the production process through the display screen 13, and can promptly discover the abnormal local temperature, which is convenient for production monitoring.

[0041] The outer periphery of the pipeline mixer 9 is provided with a jacket heat exchanger 5, and a plurality of mixing plates 91 are provided inside the pipeline mixer 9; one end of the mixing plate 91 is connected to the inner wall of the pipeline mixer 9 and is inclined toward the outlet end of the pipeline mixer 9. The jacket heat exchanger 5 is connected to the circulating water pipe of the factory, and the raw materials enter the pipeline mixer 9 and are evenly mixed by the mixing plates 91, which is convenient for subsequent production and processing.

[0042] Embodiment 4: The difference from Embodiment 1 is that the jacket heat exchanger 5 is also connected to a solenoid valve, which is connected to a single-chip microcomputer; the single-chip microcomputer is also connected to a buzzer, and the single-chip microcomputer is respectively connected to a temperature sensor and a pressure sensor. The single-chip microcomputer has a built-in control program, and is preset with a control temperature and an alarm pressure value. When in use, it automatically obtains the values ​​of the temperature sensor and the pressure sensor. When the temperature is higher or lower than the set value, the solenoid valve is controlled to make the jacket heat exchanger 5 work. At the same time, when the air pressure is higher than the set value, the buzzer is turned on to alarm. The automatic opening and closing of the jacket heat exchanger is realized by the single-chip microcomputer, which can reduce the labor intensity of the staff and facilitate normal production.

[0043] Comparative verification: In comparative example 1, the chlorination equipment uses a single continuous tubular reactor 7;

[0044] In Comparative Example 2, the chlorination equipment uses a separate dynamic tubular reactor 6;

[0045] In Comparative Example 3, the chlorination equipment is a combination of a dynamic tubular reactor and a continuous tubular reactor, which is the technical solution adopted in Example 1.

[0046] Verification 1: Cyanopyridine nitrogen oxide and phosphorus oxychloride are mixed and slurried in a mixing kettle 1, and the mixed raw materials are pumped into a continuous tubular reactor 7 using a feed pump A3; triethylamine is then pumped into the continuous tubular reactor 7 through a feed pump B4, the pump pressure is 0.2 MPa, and the feed mass ratio of phosphorus oxychloride + cyanopyridine nitrogen oxide to triethylamine is 49:5.83; the first stage reaction temperature is 30-35°C, and the residence time is 60 min; the second stage reaction temperature is 40-50°C, and the residence time is 60 min; the third stage reaction temperature is 85-70°C, and the residence time is 60 min. During the reaction process, 10 ml of samples are taken at each stage for detection. The final product content is 96.14%.

[0047] Verification 2: Cyanopyridine nitrogen oxide and phosphorus oxychloride were mixed and slurried in a mixing kettle 1, and the mixed raw materials were pumped into a dynamic tubular reactor 6 using a feed pump A3; triethylamine was then pumped into the dynamic tubular reactor 6 through a feed pump B4, and the pump pressure was 0.2 MPa; the first stage reaction temperature was 50°C, and the residence time was 60 minutes; the second stage was kept at 65-70°C, and the reaction was kept at this temperature for 1 hour; the third stage reaction temperature was 90-95°C, and the reaction was kept at this temperature for 2 hours; during the reaction, 10 ml of the dynamic tube was sampled for detection. The final product content was 99.69%.

[0048] Verification 3: Cyanopyridine nitrogen oxide and phosphorus oxychloride were mixed and slurried in a mixing kettle 1, and the mixed raw materials were pumped into the dynamic tubular reactor 6 using a feed pump A4; triethylamine was then pumped into the dynamic tubular reactor 6 through a feed pump B4, with a pump pressure of 0.2 MPa; the temperature of the first stage was 50°C, and the residence time was 60 min; after the first stage dynamic tubular reactor 6 ran stably, the raw materials mixed after the preliminary reaction were transferred to the continuous tubular reactor 7; during the reaction, 10 ml samples were taken from the dynamic tubular reactor 6 and the continuous tubular reactor 7 for testing. The dynamic tubular product content was 57.88, and the tubular reactor finally obtained a product content of 98.77%.

[0049] Through analysis and comparison, it was verified that: neither the single dynamic tubular reactor 6 nor the single continuous tubular reactor 7 can utilize the materials well, and there are many by-products; in Verification 1, the reaction time of the fully continuous tubular reactor 7 is too long, the temperature rise span is large, and the product content is relatively low; in Verification 2, the single dynamic tubular reactor 6 has a high mass yield, but the raw material reaction is not complete, and a long time of insulation is required, which reduces the product production rate; in Verification 3, the combination of the dynamic tubular reactor 6 and the continuous tubular reactor 7 can solve the problems of incomplete reaction and insulation, which can not only ensure the reaction, but also shorten the insulation reaction time, and the product content is relatively high.

[0050] In the specification of the present utility model, a lot of specific details are described. However, it is understood that the embodiments of the present utility model can be practiced without these specific details. In some examples, well-known methods, structures and techniques are not shown in detail so as not to obscure the understanding of this specification.

[0051] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model, and they should all be included in the scope of the claims and specification of the utility model.

Claims

1. A device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide, characterized in that: The invention comprises a mixing kettle (1), a feed pump A (3), a display screen (13), and a storage tank (2), a feed pump B (4), a dynamic tubular reactor (6), a continuous tubular reactor (7), and a receiving tank (8) connected in sequence; the mixing kettle (1) is connected to the feed pump A (3), and the feed pump A (3) is connected to the dynamic tubular reactor (6); the outer peripheries of the dynamic tubular reactor (6) and the continuous tubular reactor (7) are respectively provided with a jacket heat exchanger (5), and the dynamic tubular reactor (6) and the continuous tubular reactor (7) are provided with a temperature sensor (10) and a pressure sensor (11); and the display screen (13) is respectively electrically connected to the temperature sensor (10) and the pressure sensor (11).

2. The device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide according to claim 1, characterized in that: The dynamic tubular reactor (6) is provided with a side feed port and a side discharge port on the side, and a plurality of top feed ports on the top, wherein the side feed port is connected to a feed pump B (4), and the top feed port is connected to a feed pump A (3).

3. A device for producing 2-chloronicotinonitrile as claimed in claim 2, characterized in that: Temperature sensors (10) are provided between the feed pump A (3) and the dynamic tubular reactor (6) and between the feed pump B (4) and the dynamic tubular reactor (6); the temperature sensors (10) are respectively electrically connected to the display screens (13).

4. A device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide according to any one of claims 1 to 3, characterized in that: A sight glass is provided at the discharge port of the dynamic tubular reactor (6).

5. The device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide according to claim 4, characterized in that: A pipeline mixer (9) is provided between the dynamic tubular reactor (6) and the continuous tubular reactor (7); the inlet end of the pipeline mixer (9) is connected to the dynamic tubular reactor (6), and the outlet end is connected to the continuous tubular reactor (7).

6. The device for producing 2-chloronicotinonitrile by continuous chlorination of cyanopyridine nitrogen oxide according to claim 5, characterized in that: A jacketed heat exchanger (5) is provided on the outer periphery of the pipeline mixer (9), and a plurality of mixing plates (91) are provided inside the pipeline mixer (9); one end of the mixing plate (91) is connected to the inner wall of the pipeline mixer (9) and is inclined toward the outlet end of the pipeline mixer (9).

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