Biological sample storage system and sampling door plate

Abstract

The utility model provides a sampling door plate which comprises a plate body and a transfer device arranged on the plate body, and the plate body at least comprises a first transparent material layer, a second transparent material layer and a transparent heat insulation layer located between the first transparent material layer and the second transparent material layer; the transfer device has an open state and a closed state, and is provided with a sampling channel for communicating one side of the plate body with the other side of the plate body when in the open state; when the transmission device is in a closed state, the spaces on the two sides of the plate body are separated at the position of the transmission device. The sampling door plate provided by the scheme can be used for the biological sample storage system, and sampling from the biological sample storage system can be realized through the transfer device on the sampling door plate. Compared with the mode that the sampling door plate is directly opened for sampling, the sampling channel in the opened state of the transfer device is used for sampling, moisture entering the storage chamber can be effectively reduced, and then the frosting phenomenon occurring in the biological sample storage system is reduced.

Description

[0001] This application claims priority to patent application number 202410176757X, filing date February 8, 2024, and patent name “Sampling door panel, biological sample storage system and pressure control method thereof”. Technical Field

[0002] The present application relates to the field of low-temperature storage, and in particular, to a biological sample storage system and a sampling door panel. Background Art

[0003] Biological samples usually refer to samples such as biological cells, tissues and organs. The storage of biological samples usually needs to be carried out under low temperature (for example: temperature at -86°C, -196° or even lower) and dry conditions so that the biological samples can remain active for a long time.

[0004] Therefore, biological samples are usually stored in biological sample storage systems (e.g., biological sample storage boxes) to maintain a low temperature and dry environment for a long time. However, when biological samples need to be placed in or taken out, the door of the biological sample storage box usually needs to be opened to transfer the samples. When the door is opened, air will enter the storage box, resulting in frost in the storage box. If the sample boxes containing the samples are frosted, the sample boxes will stick to each other, making it difficult to take samples, which is not conducive to the preservation of biological samples. Utility Model Content

[0005] The purpose of the present application is to provide a sampling door panel and a biological sample storage system to reduce the frosting phenomenon in the biological sample storage system.

[0006] The embodiment of the present application is implemented as follows:

[0007] In the first aspect, an embodiment of the present application provides a sampling door plate, comprising a plate body and a transfer device arranged on the plate body, wherein the plate body comprises at least a first transparent material layer, a second transparent material layer and a transparent heat insulation layer located between the first transparent material layer and the second transparent material layer; the transfer device has an open state and a closed state, and the transfer device has a sampling channel connecting one side of the plate body with the other side of the plate body when in the open state; when the transfer device is in the closed state, the space on both sides of the plate body is separated at the position of the transfer device.

[0008] The sampling door panel provided by the above scheme has a transfer device, and the transfer device has a sampling channel when it is in the open state. The sampling door panel provided by the above scheme can be used in a biological sample storage system, and can realize sampling from the biological sample storage system through the transfer device on the sampling door panel. Compared with the method of directly opening the sampling door panel for sampling, sampling is performed through the sampling channel of the transfer device in the open state. When sampling, the channel connecting the storage chamber and the atmospheric environment is smaller, which can effectively reduce the moisture entering the storage chamber, thereby reducing the frosting phenomenon in the biological sample storage system. In addition, the sampling door panel is provided with a transparent heat insulation layer between the two transparent layers, which can facilitate the observation of the sample placement in the storage chamber during sampling, so as to facilitate accurate sampling; at the same time, the setting of the heat insulation layer can reduce the heat transfer on both sides of the plate body and reduce the impact of the external temperature on the storage chamber environment.

[0009] In combination with the first aspect, in some embodiments, the transfer device includes at least one layer of elastic diaphragm, and each layer of the diaphragm includes a plurality of elastic parts arranged along the circumferential direction. When the elastic part is supported by the sampling device, the elastic part is deformed to put the transfer device in an open state; when the elastic part is reset, the transfer device is in a closed state.

[0010] In the above technical solution, the transfer device includes a diaphragm, and the elastic part in the diaphragm is deformed when being resisted by the sampling device, and the transfer device automatically changes to an open state. After the sampling is completed, the force of the sampling device on the elastic part disappears, and the elastic part restores its original shape under the action of its own elasticity, thereby putting the transfer device in a closed state. The above technical solution can realize that when the sampling device is inserted into the transfer device, the transfer device passively changes to an open state, and after the sampling device takes out the sample, the transfer device actively changes to a closed state; and can realize that the transfer device is in a normally closed state without the action of external force.

[0011] In combination with the first aspect, in some embodiments, there is a seam between two adjacent elastic parts in the same layer, and the seams between two adjacent layers of the membrane sheets are staggered.

[0012] In combination with the first aspect, in some embodiments, the surface of the first transparent material layer away from the thermal insulation layer is the first outer surface of the board body, and the board body is provided with a first anti-condensation device, which is used to heat the first outer surface of the board body.

[0013] In the above technical solution, the first anti-condensation device is used to heat the side of the sampling door panel that is in direct contact with the atmospheric environment, which can increase the temperature of the sampling door panel and thus improve the situation caused by condensation on the sampling door panel, making it easier to observe the storage room during the sampling process.

[0014] In combination with the first aspect, in some embodiments, it further includes an anti-condensation sensor for detecting the temperature of the first outer surface; the first anti-condensation device is configured to heat the first outer surface of the plate body according to the detection result of the anti-condensation sensor.

[0015] The anti-condensation sensor can be used to monitor the temperature of the first outer surface and calculate the temperature difference between the first outer surface and the atmospheric environment. The first anti-condensation device is controlled to heat the plate body according to the monitoring result of the anti-condensation sensor, thereby reducing energy consumption and effectively reducing the impact of continuous heating of the first anti-condensation device on the temperature in the storage room.

[0016] In a second aspect, an embodiment of the present application provides a biological sample storage system, comprising a first shell and a sampling door plate provided in the first aspect, wherein the sampling door plate and the first shell form a storage chamber for placing samples, and the storage chamber is connected to the outside of the storage chamber through the sampling channel.

[0017] The biological sample storage system provided by the above solution can sample from the storage chamber through the transfer device on the sampling door panel, thereby reducing the ambient gas containing water vapor entering the storage chamber during the sampling process, and can reduce frosting in the storage chamber.

[0018] In a third aspect, an embodiment of the present application provides a biological sample storage system, comprising a first shell and a sampling door plate provided in the first aspect, wherein the sampling door plate and the first shell form a storage chamber for placing samples, and the storage chamber is connected to the atmospheric environment through the sampling channel; the first outer surface is arranged away from the storage chamber;

[0019] It also includes a control system, the first anti-condensation device is connected to the control system signal, and the control system is configured to: control the first anti-condensation device to heat the first outer surface so that the temperature of the first outer surface is not lower than a preset temperature.

[0020] In the above technical solution, the first anti-condensation device is controlled by the control system to heat the first outer surface, so that the heating temperature can be controlled more accurately.

[0021] In the third aspect, an embodiment of the present application provides a biological sample storage system, comprising a first shell and a sampling door plate provided in the first aspect, the sampling door plate and the first shell forming a storage chamber for placing samples, the storage chamber being connected to the atmospheric environment through the sampling channel; the first outer surface is arranged away from the storage chamber; and a control system is also included, the first anti-condensation device and the anti-condensation sensor are both connected to the control system signal, and the control system is configured to: control the first anti-condensation device to heat the first outer surface through the measurement data of the anti-condensation sensor, so that the temperature of the first outer surface is not lower than a preset temperature.

[0022] In the above technical scheme, the control system controls the first anti-condensation device to heat the first outer surface according to the monitoring result of the anti-condensation sensor, which can reduce the working time of the first anti-condensation device when there is no condensation on the first outer surface, reduce energy consumption, and effectively reduce the impact of continuous heating of the first anti-condensation device on the temperature in the storage room.

[0023] In a third aspect, an embodiment of the present application provides a biological sample storage system, comprising a first shell and a sampling door plate provided in the first aspect, wherein the sampling door plate is arranged in the first shell, and the first shell includes a storage chamber for storing samples; further comprising a control system and a gas supply device, wherein the gas supply device is connected to the storage chamber via a first air outlet pipe, and the gas supply device is connected to the control system; the control system is configured to: control the gas supply device to fill the storage chamber with gas.

[0024] In the above technical solution, by setting up a gas providing device and connecting it to the storage chamber, gas can be introduced into the storage chamber. On the one hand, the pressure in the storage chamber can be adjusted. On the other hand, gas can be introduced into the storage chamber during the sampling process to make the pressure in the storage chamber greater than the air pressure of the atmospheric environment, thereby reducing the ambient gas entering the storage chamber from the atmospheric environment during the sampling process, thereby achieving the purpose of reducing the amount of frost in the storage chamber.

[0025] In combination with the third aspect, in some embodiments, the first shell also includes an operating chamber for sampling, and the operating chamber is selectively connected to the storage chamber. The sampling door panel is arranged in the operating chamber, and a manipulator is arranged in the operating chamber. The manipulator is used to transfer the sample in the storage chamber to the operating chamber, and to send the sample in the operating chamber out of the operating chamber through the transfer device of the sampling door panel.

[0026] In the above technical solution, the sample in the storage chamber is taken out and sent out of the operation room by a manipulator, and the sampling personnel do not need to put their hands into the storage chamber, thus avoiding the damage to the hands of the sampling personnel caused by low temperature. In addition, in the above technical solution, during the entire sampling process, the storage chamber is not connected to the atmospheric environment, which can effectively improve the situation where there is a lot of frost in the storage chamber due to the entry of ambient gas into the storage chamber during the sampling process. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0028] Figure 1 A schematic diagram of a sampling door panel provided in an embodiment of the present application;

[0029] Figure 2 One of the structural schematic diagrams of the diaphragm provided in the embodiment of the present application;

[0030] Figure 3 The second structural schematic diagram of the diaphragm provided in the embodiment of the present application;

[0031] Figure 4 The third structural schematic diagram of the diaphragm provided in the embodiment of the present application;

[0032] Figure 5 The fourth structural schematic diagram of the diaphragm provided in the embodiment of the present application;

[0033] Figure 6 A side view of a biological sample storage system provided by an embodiment of the present application;

[0034] Figure 7 for Figure 6 Cross-sectional view at the AA position;

[0035] Figure 8 for Figure 6 A front view of the biological sample storage system is shown;

[0036] Fig. 9 for Figure 8 Cross-section view at the mid-BB position;

[0037] Fig.10 for Figure 6 The biological sample storage system shown is a front view with the insulation door removed;

[0038] Fig.11 for Figure 6The schematic diagram of the biological sample storage system shown is a schematic diagram of the biological sample storage system after the thermal insulation door and the sampling door panel are removed;

[0039] Fig.12 One of the schematic diagrams of the refrigeration chamber and the storage chamber being connected to each other provided in the embodiment of the present application (the first shell in the figure is a single-layer structure);

[0040] Fig.13 The second schematic diagram of the refrigeration chamber and the storage chamber being connected to each other provided in the embodiment of the present application;

[0041] Fig.14 The third schematic diagram of the refrigeration chamber and the storage chamber being connected to each other provided in the embodiment of the present application;

[0042] Fig.15 A schematic diagram of the three-dimensional structure of a biological sample storage system provided in one embodiment of the present application;

[0043] Fig.16 This is a schematic diagram of the interior of a biological sample storage system provided in one embodiment of the present application.

[0044] Icons: 1000-biological sample storage system; 1100-first shell; 1110-inner shell; 1111-partition; 1112-side panel; 1113-air outlet channel; 1114-return air channel; 1115-first horizontal flow channel; 1116-second horizontal flow channel; 1117-vertical flow channel; 1120-outer shell; 1130-storage room; 1140-refrigeration room; 1150-operation room; 1200- The second shell; 1300 - insulation layer; 1400 - insulation door; 1410 - window; 1420 - cover plate; 1500 - driving device; 1510 - driving motor; 1600 - refrigeration module; 1610 - cold source; 1700 - baffle; 1800 - sampling door plate; 1810 - plate body; 1820 - transfer device; 1821 - diaphragm; 18211 - elastic part; 18212 - connecting ring; 1900 - manipulator. DETAILED DESCRIPTION

[0045] In order to make the purpose, technical solution and advantages of the embodiments of the present application clearer, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all the embodiments. The components of the embodiments of the present application described and shown in the drawings here can be arranged and designed in various different configurations.

[0046] Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the present application for which protection is sought, but merely represents selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in the field without creative work are within the scope of protection of the present application.

[0047] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0048] In the description of this application, it should be noted that the terms "center", "upper", "lower", "vertical", "horizontal", "inner", "outer", etc. indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, or the positions or positional relationships in which the product of the application is usually placed when in use. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific position, be constructed and operated in a specific position, and therefore cannot be understood as a limitation on this application. In addition, the terms "first", "second", "third", etc. are only used to distinguish the description, and cannot be understood as indicating or implying relative importance.

[0049] In addition, the terms "horizontal", "vertical", "overhanging" and the like do not mean that the components are required to be absolutely horizontal or overhanging, but can be slightly tilted. For example, "horizontal" only means that its direction is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0050] In the description of this application, it should also be noted that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0051] The inventor of the present application discovered that during the sampling process, since the storage chamber for placing the sample in the biological sample storage system is connected to the atmospheric environment, the ambient gas containing water vapor enters the biological storage system, and the water vapor condenses in the low temperature environment of the storage chamber, thereby causing frost to form in the storage chamber of the biological sample storage system. Currently, there is no better solution to the problem of frost in the storage chamber of the biological sample storage system. In the prior art, the frost is mostly melted after the storage chamber is frosted, rather than reducing the amount of frost.

[0052] For existing biological sample storage systems, frosting first occurs at the location with the lowest temperature, that is, frosting first occurs on the evaporator. Accordingly, current defrosting methods mostly use a heating device to be provided on the evaporator to melt the frost on the evaporator, but this does not reduce the occurrence of frosting in the storage chamber. In addition, the method of melting the frost by providing a heating device is not applicable to the sample box, that is, the sample box cannot be heated, and therefore, the problem of frosting on the sample box cannot be improved. Furthermore, since the evaporator is heated, the temperature of the evaporator may be higher than the temperature of the sample box, and therefore, the existing defrosting methods may make the problem of frosting on the sample box more serious.

[0053] Based on this, the inventor of the present application provides a biological sample storage system 1000 for reducing the occurrence of frost in the storage chamber 1130 .

[0054] like Figure 1 and Figures 9 to 11 As shown, the biological sample storage system 1000 provided in the present application includes a first housing 1100 and a sampling door plate 1800 . The first housing 1100 has a storage chamber 1130 for placing samples.

[0055] Further, in some embodiments, the sampling door plate 1800 and the first shell 1100 enclose a storage chamber 1130, that is, the storage chamber 1130 is in contact with a surface of the sampling door plate 1800. The sampling door plate 1800 may be located at the front side of the storage chamber 1130, or at the left side, right side, rear side, or upper side of the storage chamber 1130. The sampling door plate 1800 includes a plate body 1810 and a transfer device 1820 disposed on the plate body 1810, wherein the plate body 1810 is connected to the first shell 1100, and the transfer device 1820 has an open state and a closed state, that is, the state of the transfer device 1820 can be changed. The transfer device 1820 has a sampling channel connecting one side of the plate body 1810 with the other side of the plate body 1810 when in the open state; when the transfer device 1820 is in the closed state, the space on both sides of the plate body 1810 is separated at the position of the transfer device 1820. Ideally, the spaces on both sides of the plate body 1810 are separated at the position of the transfer device 1820, which means that the spaces on both sides are completely isolated. However, in actual operation, it is difficult to completely separate the spaces on both sides of the plate body 1810 at the position of the transfer device 1820. Therefore, the transfer device 1820 has a large blocking effect on the gas exchange between the spaces on both sides. However, the situation that there is still a small amount of gas exchange between the spaces on both sides of the transfer device 1820 should also be understood as the spaces on both sides of the plate body 1810 being separated at the position of the transfer device 1820. In other embodiments, the storage chamber 1130 may not be in contact with the sampling door plate 1800.

[0056] It is easy to understand that when the transfer device 1820 is in the open state, one side and the other side of the plate body 1810 are interconnected through the sampling channel. After the sampling door plate 1800 is applied to the biological sample storage system 1000, when the transfer device 1820 is in the open state, the sample in the biological sample storage system 1000 can be taken out through the sampling channel. After the sampling is completed, the transfer device 1820 is restored to the closed state, which can effectively prevent the ambient gas containing water vapor in the atmosphere from entering the storage chamber 1130. Accordingly, when the transfer device 1820 is in the closed state, the storage chamber 1130 is separated from the atmospheric environment to prevent the gas exchange between the storage chamber 1130 and the atmospheric environment. Furthermore, the storage chamber 1130 and the atmospheric environment are separated, which means that the storage chamber 1130 and the atmospheric environment are completely isolated. However, in actual operation, it is difficult to completely separate the storage chamber 1130 and the atmospheric environment at the position of the transfer device 1820. Therefore, the transfer device 1820 achieves a large blocking effect on the gas exchange between the storage chamber 1130 and the atmospheric environment. However, the situation where there is still a small amount of gas exchange between the storage chamber 1130 and the atmospheric environment should also be understood as the storage chamber 1130 and the atmospheric environment being separated.

[0057] During the sampling operation using the biological sample storage system 1000 provided in the present application, sampling is performed through the sampling channel of the transfer device 1820 on the sampling door panel 1800 in the open state, rather than opening the sampling door panel 1800 for sampling. Therefore, when sampling is performed, the channel connecting the storage chamber 1130 and the atmospheric environment is smaller, which can effectively reduce the ambient gas containing water vapor in the atmospheric environment from entering the storage chamber 1130, thereby reducing the amount of frost in the storage chamber 1130 and improving the frost condition in the storage chamber 1130.

[0058] It should not be difficult for technicians in this field to understand that a through hole or a notch should be set on the plate body 1810, and the transfer device 1820 should be installed at the position of the through hole or the notch, so that the transfer device 1820 can connect the two sides of the plate body 1810 through the channel when it is in the open state; when the transfer device 1820 is in the closed state, the through hole or the notch on the plate body 1810 is basically or completely covered.

[0059] In some embodiments of the present application, the transfer device 1820 is in a normally closed state when no external force is applied. The normally closed state means that it is always in a closed state. That is, when no external force is applied, the transfer device 1820 can always remain in a closed state; during the sampling process, the transfer device 1820 can be passively opened and automatically closed at the end of the sampling process.

[0060] Among them, external force refers to the force applied by the structure outside the biological sample storage system 1000 provided in the present application, and the external force does not include gravity; passive opening means that the transfer device 1820 becomes an open state under the action of external force; automatic closing means that the transfer device 1820 automatically returns to a closed state after the external force is removed. It is not difficult to understand that the sampling device used for sampling can be extended from one side of the plate body 1810 through the transfer device 1820 to the other side of the plate body 1810. During the process of the sampling device extending into the transfer device 1820, the sampling device contacts the transfer device 1820 and applies a force to the transfer device 1820, so that the transfer device 1820 passively changes to an open state; after the sampling device takes out the sample through the sampling channel of the transfer device 1820, the transfer device 1820 actively changes to a closed state. Among them, the sampling device can be the manipulator 1900 in the automatic sampling process, or the arm of the operator in the manual sampling process.

[0061] Of course, in some other implementations, the transmission device 1820 can also be in a normally closed state by the action of external force. In the implementation of using external force to keep the transmission device 1820 in a normally closed state, it is necessary to set a force-applying device for applying external force to the transmission device 1820 and increase the structure of the sampling door plate 1800, but to a certain extent, the transmission device 1820 can be maintained in a normally closed state more stably.

[0062] For example, an automatic control method is used to realize the automatic opening and closing of the transfer device 1820 during the sampling process. For example, a sensor is used to monitor whether a sampling device is close to the transfer device 1820. When the sampling device is close to the transfer device 1820, the transfer device 1820 is automatically opened through a signal to form a sampling channel. After the sampling device completes sampling, the transfer device 1820 is automatically closed through a signal. The specific implementation method is similar to that of an existing automatic door.

[0063] In one embodiment, the transfer device 1820 is in a normally closed state without external force. Figures 1 to 5As shown, the transfer device 1820 includes at least one layer of elastic diaphragm 1821, and each layer of diaphragm 1821 includes a plurality of elastic parts 18211 arranged along the circumference, and the elastic parts 18211 are fan-shaped, that is, the elastic parts 18211 are arc-shaped pieces. It is not difficult to understand that the elastic parts 18211 are also elastic and can undergo elastic deformation. The elastic parts 18211 of the same layer can be pieced together into a circle along the circumference. There are seams between the elastic parts 18211. When the elastic parts 18211 are not subjected to external forces, the edges of the two adjacent elastic parts 18211 contact each other, and the size of the seams between the elastic parts 18211 is almost zero, so that the space on both sides of the diaphragm 1821 is not connected through the diaphragm 1821. At this time, the transfer device 1820 is in a closed state, and the space on both sides of the plate body 1810 is separated at the position of the transfer device 1820. In other embodiments, the diaphragm 1821 may also be rectangular or other polygonal (such as Figure 4 and Figure 5 ), the elastic portion 18211 may also be a triangular piece (such as Figure 4 ), rectangle (such as Figure 5 ) and other shapes; in the embodiment in which the diaphragm 1821 is other polygonal, the diaphragm 1821 is preferably a regular polygon with 5 to 10 sides.

[0064] When the elastic part 18211 is held by the sampling device, the elastic part 18211 will be deformed, and the edges of the two adjacent elastic parts 18211 will separate from each other, so that the transfer device 1820 is in an open state. After the sampling device completes sampling, the force applied by the sampling device to the elastic part 18211 disappears, the elastic part 18211 in the diaphragm 1821 is reset under the action of its own elasticity, and the transfer device 1820 automatically changes to a closed state. In some embodiments, the elastic part 18211 can be a silicone material structure, a silicone rubber material structure, and a rubber material structure, such as natural rubber, butadiene rubber, styrene-butadiene rubber, propylene rubber, etc., and technicians in this field can select according to the actual application scenario.

[0065] Of course, in other embodiments, the transfer device 1820 may also include two or more layers of membranes 1821. On this basis, the seams between the elastic parts 18211 in two adjacent layers of membranes 1821 are staggered to further reduce the external gas entering the storage chamber 1130 during the sampling process. In other embodiments, the seams between the elastic parts 18211 in two adjacent layers of membranes 1821 may not be staggered.

[0066] In some embodiments, Figure 2 As shown, the diaphragm 1821 may be formed by simply splicing the elastic parts 18211; in other embodiments, such as Figure 3As shown, the diaphragm 1821 further includes a connecting ring 18212, the connecting ring 18212 is annular, and the elastic part 18211 is connected to the inner side of the connecting ring 18212. Furthermore, the connecting ring 18212 and the elastic part 18211 are integrally formed and connected. Figure 3 The middle dotted line is the boundary between the elastic portion 18211 and the connecting ring 18212 .

[0067] Further, when the outer shape of the diaphragm 1821 is circular, the diameter of the diaphragm 1821 is not less than 10 cm; when the outer shape of the diaphragm 1821 is polygonal, the diameter of the inscribed circle of the diaphragm 1821 is not less than 10 cm, so as to facilitate the removal of the sample from the sampling channel. Among them, the diameter of the sampling channel is not less than 10 cm, which is the maximum value diameter that the sampling channel can reach when the diaphragm 1821 is not damaged; when the sampling channel is not circular, the diameter of the sampling channel is not less than 10 cm, which means that the diameter of the circumscribed circle of the sampling channel is not less than 10 cm. It is not difficult to understand that the smaller the diameter of the sampling channel, the less the amount of ambient gas containing water vapor that can enter the storage chamber 1130 during sampling, and the more obvious the improvement effect on the frosting problem. In the case where the diaphragm 1821 is a circular structural member, the diameter of the diaphragm 1821 is 12 to 20 cm accordingly.

[0068] In an embodiment of the present application, there may be multiple transfer devices 1820, and the multiple transfer devices 1820 are distributed on the plate 1810 according to a preset rule, such as a matrix distribution, so as to facilitate the retrieval and placement of samples at multiple positions in the storage chamber 1130.

[0069] In the present application, in order to facilitate observation of the sample box in the storage chamber 1130 through the sampling door plate 1800, so as to facilitate the transfer device 1820 to take samples from the storage chamber 1130, the plate body 1810 includes a transparent structural member, and the transparent structural member can realize observation of the situation on the other side of the plate body 1810 from one side of the plate body 1810. For example, in one embodiment, the transparent structural member can be an acrylic plate; in another embodiment, the transparent structural member can be glass.

[0070] Since the sampling door plate 1800 is in direct contact with the storage chamber 1130, and the storage chamber 1130 needs to maintain a relatively low temperature to store biological samples, the sampling door plate 1800 also has a certain heat insulation function to reduce the amount of cold that is lost from the storage chamber 1130 to the atmosphere through the sampling door plate 1800.

[0071] Furthermore, in some embodiments, in order to improve the thermal insulation performance of the sampling door plate 1800 and reduce the heat exchange between the storage chamber 1130 and the atmospheric environment, the plate body 1810 is a multi-layer structure, and the plate body 1810 includes a thermal insulation layer.

[0072] For example, the plate body 1810 at least includes a first transparent material layer, a second transparent material layer, and a transparent heat-insulating layer located between the first transparent material layer and the second transparent material layer. It is not difficult to understand that the first transparent material layer, the second transparent material layer, and the heat-insulating layer are all transparent, which can facilitate observation from one side of the plate body 1810 to the other side. Among them, the first transparent material layer and the second transparent material layer can be made of acrylic, glass or other existing transparent materials; the first transparent material layer, the second transparent material layer, and the heat-insulating layer can also be transparent but colored structural parts. The materials of the first transparent material layer and the second transparent material layer can be made of the same material or different materials. The first transparent material layer and the second transparent material layer are both plate-shaped structural parts, and the surface with the largest area in the first transparent material layer is arranged opposite to the surface with the largest area in the second transparent material layer. And the surface with the largest area in the first transparent material layer is the same size as or close to the surface with the largest area in the second transparent material layer.

[0073] The sampling door plate 1800 is applied to the biological sample storage system 1000 provided in the present application. One of the first transparent material layer and the second transparent material layer is in contact with the storage chamber 1130, and the other is arranged toward the atmospheric environment. The heat transfer between the first transparent material layer and the second transparent material layer can be reduced by the thermal insulation layer, thereby reducing the amount of cold that is dissipated from the storage chamber 1130 to the atmospheric environment through the sampling door plate 1800.

[0074] In some embodiments, the heat insulating layer may be a vacuum layer formed between the first transparent material layer and the second transparent material layer, that is, the cavity between the first transparent material layer and the second transparent material layer is a vacuum environment to reduce heat transfer between the first transparent material layer and the second transparent material layer, thereby reducing heat exchange between the storage chamber 1130 and the atmospheric environment. The vacuum layer may be formed only by the first transparent material layer and the second transparent material layer, or may be formed by the first transparent material layer, the second transparent material layer, and a square frame arranged along the edges of the first transparent material layer and the second transparent material layer.

[0075] In other embodiments, the thermal insulation layer may also be formed of a liquid, gaseous or solid structure, such as existing products such as thermal insulation cotton with a low thermal conductivity.

[0076] Furthermore, in order to ensure that the thermal insulation layer has a better thermal insulation effect, in the above embodiment, the surface size with the largest area in the thermal insulation layer is close to the first transparent material layer and the second transparent material layer, so as to reduce the relative contact area between the first transparent material layer and the second transparent material layer, thereby reducing the heat transfer between the first transparent material layer and the second transparent material layer.

[0077] In some embodiments, the plate body 1810 further includes a third transparent material layer to further reduce the amount of cold that is lost from the storage chamber 1130 to the atmosphere through the sampling door plate 1800. For example, in some other embodiments, a third transparent material layer is further provided between the first transparent material layer and the second transparent material layer. The aforementioned heat insulation layer includes a first sub-heat insulation layer located between the first transparent material layer and the third transparent material layer, and a second sub-heat insulation layer located between the second transparent material layer and the third transparent material layer.

[0078] In the biological sample storage system 1000 provided in the present application, the situation inside the storage chamber 1130 can be observed through the sampling door plate 1800; because during the sampling process, one side of the sampling door plate 1800 is in contact with the atmospheric environment and the other side is in contact with the storage chamber 1130, the temperature of the side of the sampling door plate 1800 facing the atmospheric environment is lower. Therefore, condensation will appear on the surface of the sampling door plate 1800 in contact with the atmospheric environment, making it inconvenient to observe the storage chamber 1130 during the sampling process.

[0079] Based on this, the sampling door plate 1800 provided in this embodiment is provided with a first anti-condensation device, which is used to heat the side of the sampling door plate 1800 away from the storage chamber 1130, that is, to heat the side of the sampling door plate 1800 that is in direct contact with the atmospheric environment, thereby improving the temperature of this side of the sampling door plate 1800 and thus improving the condensation caused by the excessively low temperature of the sampling door plate 1800.

[0080] For example, the plate body 1810 of the sampling door plate 1800 has a first outer surface and a second outer surface that are arranged opposite to each other, wherein the first outer surface is the surface of the first transparent material layer away from the heat insulation layer, and the second outer surface is the surface of the second transparent material layer away from the heat insulation layer. If the first transparent material layer of the sampling door plate 1800 is arranged toward the atmosphere during installation, and the second transparent material layer is in contact with the storage chamber 1130 during installation; accordingly, during use, the first outer surface will be in contact with the atmosphere, and the second outer surface will be in contact with the storage chamber 1130. Therefore, the first anti-condensation device is used to heat the first outer surface.

[0081] In some embodiments of the biological storage system, the first transparent material layer of the plate body 1810 is installed away from the storage chamber 1130, and the second transparent material layer is installed toward the storage chamber 1130; then the first outer surface of the plate body 1810 is away from the storage chamber 1130, and the second outer surface of the plate body 1810 is toward the storage chamber 1130 and in contact with the storage chamber 1130. That is, the first anti-condensation device is used to heat the surface of the first transparent material layer away from the storage chamber 1130; wherein the first anti-condensation device can be disposed on the surface of the first transparent material layer away from the storage chamber 1130, and can also be disposed on the surface of the first transparent material layer facing the storage chamber 1130.

[0082] For the sake of convenience, in the subsequent contents of this application, the present application is described with the first transparent material layer of the sampling door plate 1800 being installed away from the storage chamber 1130 and the second transparent material layer being installed toward the storage chamber 1130. That is, in the technical solutions described below, the first outer surface of the sampling door plate 1800 is the surface of the first transparent material layer away from the storage chamber 1130, and the second outer surface is the surface of the second transparent material layer facing the storage chamber 1130.

[0083] In some embodiments of the sampling door plate 1800, the first anti-condensation device includes a conductive heating film, which is preferably a transparent structural member, so that the inside of the storage chamber 1130 can be observed from the outside of the storage chamber 1130. In some embodiments, the transparent conductive heating film disclosed in the Chinese patent "A transparent conductive heating film and preparation method" (publication number CN115361751A) can be used, and in other embodiments, other existing conductive heating films can also be used.

[0084] The conductive heating film may be attached to the first outer surface by bonding to heat the first outer surface, or other connection methods may be used to heat the first outer surface.

[0085] Furthermore, the conductive heating film is disposed on the first outer surface around the transfer device 1820. For example, in one embodiment, the conductive heating film is disposed on the edges of the first transparent material layer. In another embodiment, the size of the conductive heating film may be similar to the size of the first transparent material layer, and the conductive heating film may be provided with a through hole corresponding to the transfer device 1820. When the conductive heating film is attached to the first outer surface, the transfer device 1820 is located in the through hole on the conductive heating film.

[0086] In some other embodiments of the sampling door plate 1800, the first anti-condensation device may also include a heating wire disposed at the edge of the first transparent material layer, and the heat generated by the heating wire can be transferred to the first outer surface to heat the first transparent material layer in the plate body 1810, and the heat can be transferred to the first outer surface. In this embodiment, the heating wire disposed at the edge of the first transparent material layer may mean that the heating wire is attached to the first transparent material layer along the edge of the first transparent material layer; it may also mean that the heating wire is disposed around the edge of the first transparent material layer and is disposed on the outside of the first transparent material layer.

[0087] In some embodiments, the biological sample storage system 1000 further includes a control system, and the control system is connected to the first anti-condensation device by signal, and the control system can control the first anti-condensation device to heat the first outer surface. It should not be difficult for a person skilled in the art to understand that the phenomenon of condensation on the first outer surface is because the difference between the temperature of the first outer surface and the temperature of the atmospheric environment reaches a certain value. A person skilled in the art can set a preset temperature according to the temperature of the use environment of the biological sample storage system 1000, and the preset temperature is not lower than the temperature of the use environment. By controlling the first anti-condensation device to heat the first outer surface through the control system, so that the temperature of the first outer surface is not lower than the preset temperature, the phenomenon of condensation on the sampling door panel 1800 can be effectively avoided. It is not difficult to understand that in this embodiment, the first anti-condensation device needs to work continuously.

[0088] In some other embodiments, the sampling door plate 1800 further includes an anti-condensation sensor for detecting the temperature of the first outer surface, and the anti-condensation sensor and the first anti-condensation device are both connected to the control system signal, so that the control system controls the first anti-condensation device to heat the first outer surface according to the real-time monitoring result of the anti-condensation sensor. In this embodiment, the temperature of the first outer surface can be monitored by the anti-condensation sensor, and the temperature difference between the first outer surface and the atmospheric environment can be calculated. The control system selectively controls the first anti-condensation device to heat the first outer surface of the sampling door plate 1800 away from the storage chamber 1130 according to the judgment result of the anti-condensation sensor, so that the temperature of the first outer surface is not lower than the preset temperature, and the temperature difference between the ambient temperature and the first outer surface is not greater than the preset temperature difference, so as to prevent condensation due to the excessive temperature difference between the atmospheric environment and the first outer surface.

[0089] For example, in one embodiment, when the temperature difference between the first outer surface and the atmospheric environment calculated by the anti-condensation sensor causes condensation to occur on the first outer surface, the control system controls the first anti-condensation device to heat the first outer surface of the sampling door plate 1800 away from the storage chamber 1130, so that the first outer surface is maintained at a temperature above a preset temperature. In another embodiment, the temperature difference (the temperature difference between the ambient temperature and the first outer surface) that causes condensation to occur on the first outer surface can be set as a preset temperature difference, and when the temperature difference between the atmospheric environment and the first outer surface calculated by the anti-condensation sensor is close to the preset temperature difference, the control system controls the first anti-condensation device to heat the first outer surface of the sampling door plate 1800 away from the storage chamber 1130, so that the temperature difference between the ambient temperature and the first outer surface is not greater than the preset temperature difference. The anti-condensation sensor can be an anti-condensation sensor sold on the market.

[0090] In some embodiments, the anti-condensation sensor measures the temperature of the first outer surface by contacting the first outer surface. In other embodiments, the detection end of the anti-condensation sensor may be at a certain distance from the first outer surface, as long as the measured temperature of the first outer surface is within the allowed error range; for example, in an embodiment using infrared temperature measurement, the detection end of the anti-condensation sensor may be at a certain distance from the first outer surface. As long as the first anti-condensation device is controlled to heat the plate 1810 according to the detection result of the sensor, it belongs to the inventive concept of the present application.

[0091] In the above embodiments, the first anti-condensation device can be provided to improve the condensation on the first outer surface, but there may still be a certain temperature difference between the first outer surface and the atmospheric environment, so that the water vapor in the ambient gas is liquefied on the first outer surface. Therefore, in some embodiments, a water receiving tray is further provided below the sampling door plate 1800, and the condensed water liquefied on the first outer surface can slide into the water receiving tray below under the action of gravity, so as to collect the condensed water.

[0092] Furthermore, in some embodiments, the sampling door plate 1800 is also provided with a second anti-condensation device, which is disposed in the second transparent material layer, and can achieve heating of the second outer surface, so that there is no need to distinguish between the front and back sides during the installation of the sampling door plate 1800. Furthermore, the second anti-condensation device can be disposed on the surface of the second transparent material layer facing the storage chamber 1130, or it can be disposed on the surface of the second transparent material layer away from the storage chamber 1130. For example, in one embodiment of the sampling door plate 1800, the second anti-condensation device is disposed on the second outer surface. When the sampling door plate 1800 provided in this embodiment is applied to a biological sample storage system, the first outer surface of the sampling door plate 1800 can be used to contact the storage chamber 1130, or the second outer surface can be used to contact the storage chamber 1130. In addition, the sampling door panel 1800 provided in this embodiment also has a defrosting function, which is specifically embodied in: in the installation method in which the first outer surface contacts the storage chamber 1130, the first anti-condensation device can be used to heat the first outer surface to melt the frost condensed on the first outer surface; in the installation method in which the second outer surface contacts the storage chamber 1130, the second anti-condensation device can be used to heat the second outer surface to melt the frost condensed on the second outer surface.

[0093] In this embodiment, the second anti-condensation device includes a conductive heating film, and may also include a heating wire arranged along the edge of the second outer surface. The second outer surface is heated by the heating wire, and the heat can be transferred to the center of the second outer surface. The structure and installation method of the conductive heating film and the heating wire of the second anti-condensation device can be consistent with the structure and installation method of the first anti-condensation device, which will not be repeated here. Of course, in this application, the first anti-condensation device and the second anti-condensation device can both be conductive heating films, or the first anti-condensation device and the second anti-condensation device can both be heating wires; or one of the first anti-condensation device and the second anti-condensation device can be a conductive heating film and the other can be a heating wire, which is not limited in this application.

[0094] In some embodiments of the present application, Figure 6 , 8 As shown in Figures 9 and 10, the biological sample storage system 1000 further includes a heat preservation door 1400, which is disposed on a side of the sampling door plate 1800 away from the storage chamber 1130. The heat preservation door 1400 is used to cover the sampling door plate 1800 to separate the sampling door plate 1800 from the atmospheric environment, thereby reducing the heat exchange between the sampling door plate 1800 and the atmospheric environment, thereby reducing the loss of cold in the storage chamber 1130. It is not difficult to understand that the heat preservation door 1400 can be opened. When the heat preservation door 1400 is opened, the sampling door plate 1800 is in contact with the atmospheric environment. When the heat preservation door 1400 is closed, the heat preservation door 1400 separates the sampling door plate 1800 from the atmospheric environment. When sampling or observation of the storage chamber 1130 is required, the heat preservation door 1400 can be opened, and the heat preservation door 1400 can be closed after the operation is completed. In other embodiments, the biological sample storage system 1000 may not be provided with the heat preservation door 1400. Furthermore, the heat preservation door 1400 is made of a material or structure with certain heat preservation performance.

[0095] Further, in some embodiments, Fig.15 As shown, an openable window 1410 may be provided on the heat preservation door 1400 corresponding to the transfer device 1820. When sampling, only the corresponding window 1410 needs to be opened. A cover plate 1420 that can cover the window 1410 is connected to the door panel. The window 1410 can be opened by opening the cover plate 1420, and the window 1410 can be closed by covering the window 1410 with the cover plate 1420.

[0096] In some embodiments, a sealing strip is provided on the side of the heat preservation door 1400 facing the sampling door plate 1800, and the sealing strip is provided along the edge of the sampling door plate 1800 to further reduce the loss of cold in the storage chamber 1130. The conductive heating film or heating wire provided on the edge of the sampling door plate 1800 can not only prevent condensation on the first outer surface of the sampling door plate 1800, but also heat the sealing strip to improve the aging problem of the sealing strip.

[0097] The sampling door plate 1800 in the present application can be applied to multiple fields in addition to the biological sample storage system 1000, such as:

[0098] In the field of precision instruments, some precision instruments and components need to be tested and stored under strictly controlled low-temperature environmental conditions. The sampling door panel 1800 can provide the required low-temperature dry environment.

[0099] In the medical field, medical facilities such as operating rooms, laboratories and pharmacies often need to maintain a constant low-temperature dry environment to prevent infection or drug failure. This sampling door panel 1800 can keep the air in the storage room 1130 or the equipment always at a low temperature and dry.

[0100] In the field of food and beverage processing, it is very important to keep the production environment low temperature and dry during the food and beverage production process to ensure product quality and safety. The sampling door panel 1800 can be used in the storage room 1130, production line or packaging process to ensure that the product is not affected by high temperature and humidity during processing and storage.

[0101] In the field of cultural relics protection, precious cultural relics and artworks need to be kept in a constant low temperature and dry environment to prevent decay, mildew or damage. The sampling door panel 1800 can be used in the storage room 1130 of museums, libraries and archives.

[0102] In the field of research and experiment, scientific laboratories often need to precisely control environmental conditions to conduct various experiments and research. This sampling door panel 1800 can provide a stable low-temperature dry environment for the laboratory to ensure the accuracy of the experimental results.

[0103] In the above embodiment, a refrigeration chamber 1140 is provided in the first housing 1100 and is interconnected with the storage chamber 1130. The refrigeration chamber 1140 is used to contain a medium for heat exchange, and a driving device 1500 is also provided in the refrigeration chamber 1140 for driving the medium to move toward the storage chamber 1130. The refrigeration chamber 1140 is connected with the storage chamber 1130 through the air outlet channel 1113 and the return air channel 1114; the driving device 1500 moves the gas in the storage chamber 1130 to the refrigeration chamber 1140 through the return air channel 1114, and moves the gas in the refrigeration chamber 1140 to the storage chamber 1130 through the air outlet channel 1113. It is not difficult to understand that the refrigeration chamber 1140 and the storage chamber 1130 are connected through both the air outlet channel 1113 and the return air channel 1114.

[0104] In order to reduce the cooling loss in the refrigeration chamber 1140, in some embodiments, as Fig. 9As shown, the biological sample storage system 1000 includes a second shell 1200, the first shell 1100 is located on the inner side of the second shell 1200, and a heat preservation layer 1300 is arranged between the first shell 1100 and the second shell 1200. Further, the heat preservation layer 1300 surrounds the first shell 1100 to reduce the loss of cold in the refrigeration chamber 1140. The heat preservation layer 1300 can be composed of foam or other materials with heat preservation properties. Further, in the embodiment in which the biological sample storage system 1000 also includes the second shell 1200, the heat preservation door 1400 can be connected to the first shell 1100 or the second shell 1200. The heat preservation door 1400 is rotatably connected to the second shell 1200, and the heat preservation door 1400 is opened and closed by rotating the heat preservation door 1400. When the heat preservation door 1400 is closed, the heat preservation door 1400 and the second shell 1200 enclose a chamber for accommodating the first shell 1100, and the first shell 1100 and the sampling door plate 1800 are arranged in the chamber. In other embodiments, the heat preservation door 1400 can also be arranged in the first shell 1100; the heat preservation door 1400 and the first shell 1100 or the second shell 1200 can also be connected in other ways besides the rotation connection.

[0105] Further, in some embodiments, the drive device 1500 includes an inlet and an outlet, and the drive device 1500 sucks the medium from the inlet and then discharges the medium from the outlet to achieve the flow of the medium. In the embodiment in which the medium in the refrigeration chamber 1140 is a gas, the drive device 1500 can be a fan, preferably a turbo fan. In other embodiments, the medium is a liquid, and the drive device 1500 can be a water pump. In other embodiments, the drive device 1500 can also be just a blade that rotates in the refrigeration chamber 1140. Further, the drive device 1500 is also connected to a drive motor 1510, and the drive motor 1510 is arranged outside the first housing 1100.

[0106] like Figure 7 As shown, a cold source 1610 is provided at the outlet of the driving device 1500, so that the medium can better exchange heat with the cold source 1610 after being discharged from the outlet, thereby having a lower temperature. A baffle 1700 is also provided at the outlet of the driving device 1500, and the outlet of the driving device 1500 is separated from the inlet by the baffle 1700, so that the medium moves away from the inlet after being discharged from the outlet, so as to better cool the storage chamber 1130.

[0107] The biological storage system includes a refrigeration module 1600. In some embodiments, the refrigeration module 1600 includes the aforementioned cold source 1610, which passes through the refrigeration chamber 1140 and performs heat exchange with the medium in the refrigeration chamber 1140, so that the medium in the refrigeration chamber 1140 carries cold energy. The refrigeration module 1600 can adopt the related existing technologies in the prior art, such as the refrigeration module 1600 can include a module with refrigeration function composed of a compressor, a condenser, a throttle valve and an evaporator commonly used in the refrigeration field, and the cold source 1610 is the evaporator. The cold source 1610 passes through the refrigeration chamber 1140 and performs heat exchange with the medium in the refrigeration chamber 1140, so that the medium in the refrigeration chamber 1140 carries cold energy. The medium in the refrigeration chamber 1140 can be a gas (for example: air, nitrogen, etc.). Of course, the refrigeration module 1600 can also adopt other existing refrigeration equipment; the medium in the refrigeration chamber 1140 can also be a liquid.

[0108] In other embodiments, the cold source 1610 in the refrigeration module 1600 may also be a coil arranged around the inner shell 1110; the refrigeration module 1600 may also be a pipeline for providing a low-temperature medium to the refrigeration chamber 1140, such as the refrigeration module 1600 is connected to the refrigeration chamber 1140 so that the low-temperature medium is continuously delivered to the refrigeration chamber 1140.

[0109] In some embodiments, Fig.12 As shown, the biological sample storage system 1000 further includes a partition 1111, which is used to separate the driving device 1500 from the storage chamber 1130 to prevent the driving device 1500 from affecting the samples in the storage chamber 1130. For example, when the driving device 1500 is a fan, it can prevent water droplets attached to the fan blades of the fan from being thrown onto the sample box. In addition, the partition 1111 can also separate the interior of the first housing 1100 into a refrigeration chamber 1140 and a storage chamber 1130.

[0110] The partition 1111 has a first edge and a second edge opposite to each other. In some embodiments, the air outlet channel 1113 is arranged along the first edge, and the air return channel 1114 is arranged along the second edge. Fig.12 In other embodiments, the air outlet channel 1113 may be formed by the first edge of the partition plate 1111 and the inner side of the first housing 1100 , and the air return channel 1114 may be formed by the second edge of the partition plate 1111 and the inner side of the first housing 1100 .

[0111] Preferably, the air outlet channel 1113 is disposed above the return air channel 1114 , and after the medium carrying cold energy enters the storage chamber 1130 from the air outlet channel 1113 , the medium is easy to move downward, thereby achieving a better cooling effect on the refrigeration chamber 1140 .

[0112] In some other embodiments, the first housing 1100 includes an inner housing 1110 and an outer housing 1120. The inner housing 1110 is located inside the outer housing 1120, and a refrigeration chamber 1140 is formed between the inner housing 1110 and the outer housing 1120. The sampling door panel 1800 and the inner housing 1110 enclose a storage chamber 1130 for placing samples. One side of the refrigeration chamber 1140 is in contact with the outer surface of the inner housing 1110, and the other side is in contact with the inner surface of the outer housing 1120. The storage chamber 1130 is in contact with the inner surface of the inner housing 1110 (i.e., the inner surface of the inner housing 1110 is the side wall of the storage chamber 1130). A medium for heat exchange is provided in the refrigeration chamber 1140, specifically a low-temperature medium.

[0113] The air outlet channel 1113 and the air return channel 1114 are both provided in the inner housing 1110. The refrigeration chamber 1140 and the storage chamber 1130 are connected through both the air outlet channel 1113 and the air return channel 1114. The medium in the refrigeration chamber 1140 can enter the storage chamber 1130. The air outlet channel 1113 and the air return channel 1114 are preferably disposed opposite to each other on both sides of the storage chamber 1130.

[0114] In Figure 7 In the embodiment shown in Fig.13 the storage chamber 1130 is located inside the inner housing 1110, and a refrigeration chamber 1140 is formed between the outer housing 1120 and the inner housing 1110. The refrigeration chamber surrounds the storage chamber 1130 from the left and right sides of the storage chamber 1130. The lower end of the inner housing 1110 is connected to the inner side of the outer housing 1120. The inner housing 1110 has a longitudinal cross-section in an inverted "U" shape. The inner housing 1110 includes a partition 1111 at the top and side plates 1112 connected to both sides of the partition 1111 and extending vertically. The side plates 1112 are spaced apart from the outer housing 1120 and form a channel for the medium to flow, as Figure 7 In Fig.13 shown, there is a gap between the side plates 1112 and the outer housing 1120. Through holes are provided on both opposite side plates 1112 in the inner housing 1110. The through holes on one side plate 1112 form the air outlet channel 1113, and the through holes on the other side plate 1112 form the air return channel 1114; the air outlet channel 1113 and the air return channel 1114 are disposed opposite to each other in the horizontal direction, so that the low-temperature gas in the refrigeration chamber 1140 can enter and exit the storage chamber 1130 from both sides in the horizontal direction of the storage chamber 1130. Further, a plurality of air outlet channels 1113 and air return channels 1114 are spaced apart in the vertical direction on the side plates 1112.

[0115] Figure 7 In Fig.13In the illustrated embodiment, the driving device 1500 is disposed above the partition 1111, and the driving device 1500 is separated from the storage chamber 1130 by the partition 1111. The low-temperature gas of the refrigeration chamber 1140 enters the storage chamber 1130 from one side of the storage chamber 1130 in the horizontal direction through the air outlet channel 1113, and then enters the refrigeration chamber 1140 from the other side in the horizontal direction through the return air channel 1114. Figure 7 and Fig.13 The arrow in the middle indicates the flow direction of the gas. In other embodiments, the driving device 1500 may also be disposed on the left or right side of the storage chamber 1130 .

[0116] Furthermore, the refrigeration chamber 1140 may be formed with an annular flow channel surrounding the storage chamber 1130 on the inner side, and the annular flow channel has an annular cross section on a vertical plane. Fig.14 In the illustrated embodiment, the direction indicated by the arrow in the figure is the flow direction of the gas. The longitudinal cross-sections of the inner shell 1110 and the outer shell 1120 are both in the shape of a "mouth". A refrigeration chamber 1140 with an annular cross-section is provided between the inner shell 1110 and the outer shell 1120, that is, the refrigeration chamber 1140 includes a first horizontal flow channel 1115 located above the inner shell 1110, a second horizontal flow channel 1116 located below the inner shell 1110, and a vertical flow channel 1117 connecting the first horizontal flow channel 1115 and the second horizontal flow channel 1116. Through holes are provided at the top and the bottom of the inner shell 1110 to form an air outlet channel 1113 and a return air channel 1114, such as the air outlet channel 1113 is located at the top of the inner shell 1110, and the return air channel 1114 is located at the bottom of the inner shell 1110. It is not difficult to understand that, as Fig.14 As shown, the first horizontal flow channel 1115 and the second horizontal flow channel 1116 are connected to the return air channel 1114 through the air outlet channel 1113 and the storage chamber 1130 in sequence in addition to the vertical flow channel 1117.

[0117] The vertical flow channel 1117 is at least distributed on at least one of the left side, right side and rear side of the storage chamber 1130. For example, the vertical flow channel 1117 can be distributed on the left and right sides of the storage chamber 1130, and accordingly, the sampling door plate 1800 is installed on the front side, rear side or upper side of the storage chamber 1130; the vertical flow channel 1117 can also be distributed on the front and rear sides of the storage chamber 1130, and accordingly, the sampling door plate 1800 is installed on the left or right side of the storage chamber 1130. The vertical flow channel 1117 can also be located only on the front side, rear side, left side or right side of the storage chamber 1130.

[0118] The refrigerating chamber 1140 is provided with a driving device 1500 for driving the flow of gas and a cold source 1610 for providing cold. Under the action of the driving device 1500, the gas in the refrigerating chamber 1140 enters the storage chamber 1130 from the refrigerating chamber 1140 through the air outlet channel 1113, and then returns to the refrigerating chamber 1140 from the storage chamber 1130 through the return air channel 1114, so as to realize the circulation of gas, and transfer the low temperature of the cold source 1610 to the storage chamber 1130 during the flow. In other embodiments, the driving device 1500 can be arranged above the storage chamber 1130 or below the storage chamber 1130; through holes can also be arranged on both the left and right sides of the inner shell 1110 to form the air outlet channel 1113 and the return air channel 1114; through holes can also be arranged on both the front and rear sides of the inner shell 1110 to form the air outlet channel 1113 and the return air channel 1114.

[0119] In some embodiments of the present application, the biological sample storage system 1000 also includes a gas supply device, which is connected to the storage chamber 1130 through a first gas outlet pipe to fill gas into the storage chamber 1130 to increase the pressure in the storage chamber 1130, thereby avoiding the situation where ambient gas containing water vapor infiltrates into the storage chamber 1130 due to the low air pressure in the storage chamber 1130.

[0120] Furthermore, the gas providing device provides cold and dry gas, that is, the temperature and humidity of the gas filled into the storage chamber 1130 through the gas providing device are relatively low, which can not only reduce the impact on the temperature in the storage chamber 1130, but also further improve the frost problem in the storage chamber 1130.

[0121] Further, the gas supply device is connected to the control system signal, and the control system fills the gas supply device into the storage chamber 1130 with gas. Specifically, in some embodiments, the gas supply device includes a gas tank and a solenoid valve, and the gas tank is used to store cold and dry gas. The gas tank is connected to the storage chamber 1130 through a pipeline, and the solenoid valve is arranged on the pipeline. The solenoid valve is connected to the control system, and the gas tank can be connected to the storage chamber 1130 through the solenoid valve, so that the gas in the gas tank enters the storage chamber 1130. In actual use, the gas pressure in the gas tank is preferably greater than the gas pressure in the storage chamber 1130. In other embodiments, components such as a pressure regulating valve and a flow meter can also be arranged on the pipeline connecting the gas tank and the storage chamber 1130 to adjust the flow rate and output pressure in the pipeline.

[0122] In some embodiments, the gas providing device also includes an air compressor, a cold dryer, and a nitrogen generator. The air compressor is connected to the cold dryer to compress the air and send it to the cold dryer. The cold dryer is used to remove water vapor in the air and cool the air. The cold dryer is connected to the nitrogen generator to extract nitrogen from the air. The nitrogen generator is also connected to the gas tank to send the extracted nitrogen into the gas tank. In some other embodiments, the gas providing device may not include a nitrogen generator, and the cold dryer directly sends the treated gas into the gas tank. In other embodiments, the gas providing device may also use other equipment in the prior art that can produce cold and dry gas.

[0123] In some embodiments, a first pressure sensor for monitoring the air pressure in the storage chamber 1130 is also provided, and the first pressure sensor is connected to the control system signal; when the first pressure sensor detects that the air pressure in the storage chamber 1130 is lower than the first preset pressure, the control system sends a signal to the solenoid valve to open the solenoid valve, and the cold dry air in the gas tank enters the storage chamber 1130 under the action of the pressure in the tank, so that the pressure in the storage chamber 1130 increases; further, when the first pressure sensor detects that the air pressure in the storage chamber 1130 increases to the second preset pressure, the control system sends a signal to close the solenoid valve. Through the pressure control method provided in this embodiment, the pressure in the storage chamber 1130 can be maintained within a preset pressure range, such as 95KPa to 105KPa, which can meet the pressure requirements for sample storage on the one hand, and effectively prevent moisture in the atmospheric environment from entering the storage chamber 1130 and causing frost on the other hand. Before using the biological sample storage system 1000 provided in this embodiment, the gas in the storage chamber 1130 can be evacuated by using a vacuum pump, so that the storage chamber 1130 maintains a pressure state for about one minute, and then the solenoid valve is opened through the control system to allow the gas in the gas tank to enter the storage chamber 1130. Furthermore, the flow rate and pressure of the gas can be adjusted through the flow meter and pressure regulating valve on the pipeline. Then, the storage chamber 1130 is heated, and after a certain period of time, the refrigeration module 1600 is started to work to reduce the temperature in the storage chamber 1130 to a temperature for storing samples.

[0124] Furthermore, it also includes a door opening detection device for monitoring whether the thermal insulation door 1400 is open; the door opening detection device is connected to the control system signal. Among them, the door opening detection device can be a travel switch, or it can be a sensor for detecting position changes, including but not limited to an angle sensor, a displacement sensor, etc. In the above-mentioned embodiment in which the thermal insulation door 1400 is rotatably connected to the second shell 1200, the door opening detection device can be installed on the side of the thermal insulation door 1400 away from the rotation connection. Further, the door opening detection device is preferably installed above the side; the door opening detection device can be installed on the thermal insulation door 1400, or it can be installed on the second shell 1200. It is not difficult to understand that in the process of sampling, the thermal insulation door 1400 needs to be opened first, and then the sampling is carried out through the transfer device 1820 of the sampling door plate 1800, and finally the thermal insulation door 1400 is closed.

[0125] In the embodiment in which the door opening detection device is provided, the control system can also send a signal to the gas supply device when the door opening detection device detects that the heat preservation door 1400 is opened, so that the gas supply device fills gas into the storage chamber 1130 until the door opening detection device detects that the heat preservation door 1400 is closed. Specifically, when the door opening detection device detects that the heat preservation door 1400 is opened, the control system sends a signal to the solenoid valve on the pipeline connecting the gas storage tank and the storage chamber 1130, so that the gas in the gas storage tank enters the storage chamber 1130 under pressure until the door opening detection device detects that the heat preservation door 1400 is closed. When the biological sample storage system 1000 provided in this embodiment is used, it can automatically fill the storage chamber 1130 when the heat preservation door 1400 is opened, so that the storage chamber 1130 has a higher pressure. During the sampling process, the gas in the storage chamber 1130 overflows outward, effectively reducing the ambient gas containing water vapor entering the storage chamber 1130 from the atmospheric environment during the sampling process.

[0126] In some embodiments of the present application, a robot 1900 (i.e., the aforementioned sampling device) may be used to automatically sample from the storage chamber 1130. Fig.15 and 16In the illustrated embodiment, the first housing 1100 further includes an operation room 1150 for sampling, and the operation room 1150 is selectively connected to the storage room 1130. A manipulator 1900 for sampling from the storage room 1130 is provided in the operation room 1150. The selective connection between the operation room 1150 and the storage room 1130 means that the operation room 1150 and the storage room 1130 can be switched between connection and disconnection. For example, an openable automatic door can be provided between the operation room 1150 and the storage room 1130, and the connection and disconnection between the operation room 1150 and the storage room 1130 can be achieved by opening and closing the automatic door. For those skilled in the art, the automatic door and the hardware and software for controlling the opening and closing of the automatic door are already prior art and will not be described in detail here.

[0127] Furthermore, in some embodiments, a second pressure sensor for detecting the pressure in the operating chamber 1150 is also provided, and the second pressure sensor is also connected to the control system; the gas supply device is also connected to the operating chamber 1150 through a second gas outlet pipe. In this embodiment, the control system can control the gas supply device to fill the operating chamber 1150 with gas. For example, a solenoid valve connected to the control system signal is provided on the second gas outlet pipe, and the solenoid valve is opened by the control system, so that the gas in the gas supply device can enter the operating chamber 1150. When the biological sample storage system 1000 provided in this embodiment is in use, the gas supply device can provide gas to the storage chamber 1130 and the operating chamber 1150, so that the pressure in the storage chamber 1130 is greater than the pressure in the operating chamber 1150, and the pressure in the operating chamber 1150 is greater than the external atmospheric pressure. In order to reduce the ambient gas entering the storage chamber 1130, thereby reducing the occurrence of frost in the storage chamber 1130. In addition, due to the existence of the operating chamber 1150, water vapor in the ambient gas will first pass through the operating chamber 1150 and frost in the operating chamber 1150, which can also reduce the occurrence of frost in the storage chamber 1130.

[0128] Furthermore, the sampling door plate 1800 is disposed on a side of the operating chamber 1150 away from the storage chamber 1130 and in contact with the operating chamber 1150; the sampling door plate 1800 is connected to the first housing 1100 and does not contact the storage chamber 1130; the operating chamber 1150 and the storage chamber 1130 are separated by other structures. Fig.16 As shown, the sample taken from the storage chamber 1130 to the operation chamber 1150 by the robot 1900 can be sent out of the operation chamber 1150 through the transfer device 1820 on the sampling door panel 1800.

[0129] Of course, in some other embodiments, the sampling door plate 1800 may be in contact with the storage chamber 1130 and the operating chamber 1150 at the same time. For example, the storage chamber 1130 and the operating chamber 1150 are separated by the sampling door plate 1800, and the storage chamber 1130 and the operating chamber 1150 are connected through the transfer device 1820 in an open state.

[0130] The above description is only the preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims

1. A sampling door panel, characterized in that: It includes a plate body and a transfer device arranged on the plate body, wherein the plate body at least includes a first transparent material layer, a second transparent material layer and a transparent heat-insulating layer located between the first transparent material layer and the second transparent material layer; the transfer device has an open state and a closed state, and the transfer device has a sampling channel connecting one side of the plate body with the other side of the plate body when in the open state; when the transfer device is in a closed state, the space on both sides of the plate body is separated at the position of the transfer device.

2. The sampling door panel according to claim 1, characterized in that: In the absence of external force, the transmission device is in a normally closed state.

3. The sampling door panel according to claim 2, characterized in that: The transfer device is configured as follows: a sampling device for sampling can extend from one side of the plate body through the transfer device to the other side of the plate body; during the process of the sampling device extending into the transfer device, the transfer device passively changes to an open state; after the sampling device takes out the sample, the transfer device actively changes to a closed state.

4. The sampling door panel according to claim 3, characterized in that: The transfer device includes at least one layer of elastic diaphragm, and each layer of the diaphragm includes a plurality of elastic parts arranged along the circumferential direction. When the elastic part is supported by the sampling device, the elastic part is deformed to put the transfer device in an open state; when the elastic part is reset, the transfer device is in a closed state.

5. The sampling door panel according to claim 4, characterized in that: There is a seam between two adjacent elastic parts in the same layer, and the seams between two adjacent layers of the membrane sheets are staggered.

6. The sampling door panel according to claim 4, characterized in that: Each layer of the diaphragm is circular, and each of the elastic parts is an arc-shaped piece.

7. The sampling door panel according to claim 6, characterized in that: The diameter of the membrane is 12 to 20 cm.

8. The sampling door panel according to claim 6, characterized in that: The diaphragm is polygonal, and each of the elastic parts is a triangular piece.

9. The sampling door panel according to any one of claims 4 to 8, characterized in that: The diaphragm is a structural member made of silicone rubber material.

10. The sampling door panel according to any one of claims 1 to 8, characterized in that: The heat insulation layer is a vacuum layer.

11. The sampling door panel according to any one of claims 1 to 8, characterized in that: A plurality of the transfer devices are distributed in a matrix on the plate.

12. The sampling door panel according to any one of claims 1 to 8, characterized in that: The first transparent material layer and the second transparent material layer are glass material structures.

13. The sampling door panel according to any one of claims 1 to 8, characterized in that: The surface of the first transparent material layer away from the heat insulation layer is the first outer surface of the board body. The board body is provided with a first anti-condensation device, and the first anti-condensation device is used to heat the first outer surface of the board body.

14. The sampling door panel according to claim 13, characterized in that: The first anti-condensation device includes a conductive heating film disposed on the first outer surface, and the conductive heating film is attached to the first outer surface.

15. The sampling door panel according to claim 14, characterized in that: The conductive heating film is arranged on the edges of the first transparent material layer.

16. The sampling door panel according to claim 13, characterized in that: The first anti-condensation device includes a heating wire arranged at an edge of the first transparent material layer, the heating wire is configured to heat the plate body, and the heat can be transferred to the first outer surface.

17. The sampling door panel according to any one of claims 14 to 16, characterized in that: It also includes an anti-condensation sensor for detecting the temperature of the first outer surface; the first anti-condensation device is configured to heat the first outer surface of the plate body according to the detection result of the anti-condensation sensor.

18. The sampling door panel according to claim 13, characterized in that: The surface of the second transparent material layer away from the heat insulation layer is the second outer surface of the plate body. The second outer surface is provided with a second anti-condensation device, and the second anti-condensation device is used to heat the second outer surface.

19. The sampling door panel according to claim 1, characterized in that: The plate body also includes a third transparent material layer, which is located between the first transparent material layer and the second transparent material layer. The thermal insulation layer includes a first sub-thermal insulation layer located between the first transparent material layer and the third transparent material layer, and a second sub-thermal insulation layer located between the second transparent material layer and the third transparent material layer.

20. A biological sample storage system, characterized in that: It comprises a first shell and a sampling door plate as described in any one of claims 1 to 19, wherein the sampling door plate and the first shell form a storage chamber for placing samples, and the storage chamber is connected to the outside of the storage chamber through the sampling channel.

21. The biological sample storage system according to claim 20, characterized in that: It also includes a heat-insulating door, which is arranged on a side of the sampling door plate away from the storage chamber; the heat-insulating door is used to cover the sampling door plate; when the heat-insulating door is opened, the sampling door plate is in contact with the atmospheric environment; when the heat-insulating door is closed, the heat-insulating door separates the sampling door plate from the atmospheric environment.

22. The biological sample storage system according to claim 21, characterized in that: A sealing strip is arranged on one side of the heat-insulating door facing the sampling door plate, and the sealing strip is arranged along the edge of the sampling door plate.

23. The biological sample storage system according to any one of claims 20 to 22, characterized in that: It also includes a refrigeration chamber interconnected with the storage chamber; the refrigeration chamber is used to accommodate a medium for heat exchange, and a driving device is provided in the refrigeration chamber to drive the medium to move toward the storage chamber.

24. The biological sample storage system according to claim 23, characterized in that: The refrigeration chamber is connected to the storage chamber through an air outlet channel and an air return channel; The driving device is configured to: move the gas in the storage chamber to the refrigeration chamber through the return air passage, and move the gas in the refrigeration chamber to the storage chamber through the outlet air passage.

25. The biological sample storage system according to claim 24, characterized in that: The invention comprises a partition plate arranged in the first shell, wherein the partition plate divides the interior of the first shell into the refrigeration chamber and the storage chamber.

26. The biological sample storage system according to claim 25, characterized in that: The partition plate has a first edge and a second edge opposite to each other. The air outlet channel is arranged along the first edge, and the air return channel is arranged along the second edge.

27. The biological sample storage system according to claim 25, characterized in that: The partition plate has a first edge and a second edge opposite to each other. The first edge and the inner side surface of the first shell form the air outlet channel, and the second edge and the inner side surface of the first shell form the air return channel.

28. The biological sample storage system according to claim 26 or 27, characterized in that: The air outlet channel is located above the air return channel.

29. The biological sample storage system according to claim 24, characterized in that: The first shell includes an inner shell and an outer shell, a refrigeration chamber is formed between the inner shell and the outer shell, and the inner shell is provided with the air outlet channel and the air return channel opposite to each other.

30. The biological sample storage system according to claim 29, characterized in that: The inner shell includes a partition and side panels connected to both sides of the partition; the return air channel is arranged on one of the side panels, and the outlet air channel is arranged on the other opposite side panel, and the outlet air channel and the return air channel are arranged opposite to each other in a horizontal direction.

31. The biological sample storage system according to claim 30, characterized in that: There are multiple air outlet channels and multiple air return channels, and the multiple air outlet channels and the multiple air return channels are distributed at intervals along the vertical direction on the side plate.

32. The biological sample storage system according to claim 30, characterized in that: The partition is located on the top of the inner shell, the bottom of the inner shell is connected to the outer shell, and the side plate of the inner shell is spaced apart from the outer shell to form a channel for the medium to flow.

33. The biological sample storage system according to claim 32, characterized in that: The driving device is arranged on the upper side, the left side or the right side of the inner shell.

34. The biological sample storage system according to claim 29, characterized in that: The refrigeration chamber includes a first horizontal flow channel located above the inner shell, a second horizontal flow channel located below the inner shell, and a vertical flow channel connecting the first horizontal flow channel and the second horizontal flow channel. The air outlet channel and the return air channel are arranged opposite to each other in the inner shell in the vertical direction; the first horizontal flow channel is connected to the second horizontal flow channel through the air outlet channel, the storage chamber and the return air channel in sequence.

35. The biological sample storage system according to claim 34, characterized in that: The vertical flow channel is distributed at least on the left side and / or the right side and / or the rear side of the storage chamber.

36. The biological sample storage system according to claim 35, characterized in that: The refrigeration chamber is formed with an annular flow channel surrounding the storage chamber at the inner side.

37. The biological sample storage system according to claim 36, characterized in that: The annular flow channel has an annular cross section on a vertical plane, and the driving device is arranged above the annular flow channel.

38. The biological sample storage system according to claim 23, characterized in that: A refrigeration module is also included. The refrigeration module includes a cold source. The cold source is configured to pass through the refrigeration chamber and perform heat exchange with the medium.

39. The biological sample storage system according to claim 38, characterized in that: The driving device comprises an inlet and an outlet, and the driving device is configured to suck the medium through the inlet and then discharge the medium from the outlet.

40. The biological sample storage system according to claim 39, characterized in that: The medium is gas, and the driving device is a fan.

41. The biological sample storage system according to claim 39, characterized in that: The cold source is arranged at the outlet position of the driving device.

42. The biological sample storage system according to claim 39, characterized in that: A baffle is disposed at the outlet position of the driving device, and the baffle separates the inlet from the outlet, so that the medium moves in a direction away from the inlet after being discharged from the outlet.

43. The biological sample storage system according to claim 38, characterized in that: The refrigeration module includes a compressor, a condenser, a throttle valve and an evaporator; the cold source is the evaporator; and the medium is the gas located in the refrigeration chamber.

44. The biological sample storage system according to claim 20, characterized in that: It also includes a second shell, the first shell is located inside the second shell, and an insulation layer is arranged between the first shell and the second shell.

45. The biological sample storage system according to claim 44, characterized in that: It also includes a heat-insulating door, which is connected to the second shell and forms a chamber with the second shell, and the first shell and the sampling door plate are arranged in the chamber.

46. ​​A biological sample storage system, characterized in that: It comprises a first shell and a sampling door plate according to any one of claims 13 to 18, wherein the sampling door plate and the first shell form a storage chamber for placing samples, and the storage chamber is connected to the atmospheric environment through the sampling channel; the first outer surface is arranged away from the storage chamber; It also includes a control system, the first anti-condensation device is connected to the control system signal, and the control system is configured to: control the first anti-condensation device to heat the first outer surface so that the temperature of the first outer surface is not lower than a preset temperature.

47. A biological sample storage system, characterized in that: The device comprises a first shell and the sampling door plate according to claim 17, wherein the sampling door plate and the first shell form a storage chamber for placing samples, and the storage chamber is connected to the atmospheric environment through the sampling channel; the first outer surface is arranged away from the storage chamber; It also includes a control system, wherein the first anti-condensation device and the anti-condensation sensor are both connected to the control system signal, and the control system is configured to control the first anti-condensation device to heat the first outer surface through measurement data of the anti-condensation sensor so that the temperature of the first outer surface is not lower than a preset temperature.

48. The biological sample storage system according to claim 47, characterized in that: It also includes a water receiving tray, which is located below the sampling door plate so that the liquid flowing down along the first outer surface falls into the water receiving tray.

49. A biological sample storage system, characterized in that: It comprises a first shell and a sampling door plate according to any one of claims 13 to 19, wherein the sampling door plate is arranged in the first shell, and the first shell comprises a storage chamber for storing samples; It also includes a control system and a gas supply device, wherein the gas supply device is connected to the storage chamber via a first gas outlet pipe, and the gas supply device is connected to the control system; the control system is configured to: control the gas supply device to fill the storage chamber with gas.

50. The biological sample storage system according to claim 49, characterized in that: It also includes a first pressure sensor, which is used to monitor the air pressure in the storage chamber. The first pressure sensor is connected to the control system. The control system is configured to control the gas supply device to fill gas into the storage chamber when the first pressure sensor monitors that the air pressure in the storage chamber is lower than a first preset pressure.

51. The biological sample storage system according to claim 49, characterized in that: The first shell also includes an operating chamber for sampling, and the operating chamber is selectively connected to the storage chamber. The sampling door plate is arranged in the operating chamber. A manipulator is arranged in the operating chamber, and the manipulator is used to transfer the sample in the storage chamber to the operating chamber, and send the sample in the operating chamber out of the operating chamber through the transfer device of the sampling door plate.

52. The biological sample storage system according to claim 51, characterized in that: It also includes a first pressure sensor for detecting the pressure in the storage chamber and a second pressure sensor for detecting the pressure in the operating chamber, and the first pressure sensor and the second pressure sensor are both connected to the control system; the gas supply device is also connected to the operating chamber through a second air outlet pipe, and the control system is configured to: control the gas supply device to fill the operating chamber with gas, and the pressure in the storage chamber is greater than the pressure in the operating chamber, and the pressure in the operating chamber is greater than the external atmospheric pressure.

53. The biological sample storage system according to any one of claims 49 to 52, characterized in that: It also includes a heat preservation door and a door opening detection device; the heat preservation door is used to cover the sampling door plate to separate the sampling door plate from the atmospheric environment; The control system is configured to send a signal to the gas supply device when the door opening detection device detects that the thermal insulation door is opened, so that the gas supply device fills gas into the storage chamber until the door opening detection device detects that the thermal insulation door is closed.

54. The biological sample storage system according to claim 53, characterized in that: The door opening detection device monitors a travel switch.

55. The biological sample storage system according to any one of claims 49 to 52, characterized in that: The gas supply device includes a gas storage tank and a solenoid valve connected to the control system signal, the gas storage tank is connected to the storage chamber through the first gas outlet pipe, and the solenoid valve is arranged on the first gas outlet pipe.

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