Reagent detection kit

Abstract

The reagent detection box comprises a box body and a liquid storage tank structure arranged in the box body, the liquid storage tank structure comprises a reaction tank and a plurality of liquid injection tanks, the liquid injection tanks are arranged around the reaction tank in the circumferential direction of the reaction tank, a plurality of openings are formed in the side wall of the reaction tank, each liquid injection tank is communicated with one opening, and the liquid injection tanks are arranged in the reaction tank. Each opening is provided with a flow guide part, the flow guide parts are arranged on the side wall of the reaction tank, and the flow guide parts are arranged to guide liquid in the liquid injection tank to flow into the reaction tank. According to the reagent detection box disclosed by the invention, the opening and the flow guide part are arranged on the side wall of the reaction tank, so that liquid in the liquid injection tank can flow into the reaction tank through the opening and along the flow guide part, the fluency and the stability of injecting the liquid in the liquid injection tank into the reaction tank are improved, and the overall detection efficiency and the use experience of the reagent detection box are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of biological gene detection, and in particular to a reagent detection kit. Background Art

[0002] The reagent test kit is a commonly used detection device in the field of genetic testing, usually including a reaction tank and an injection tank connected to the reaction tank. Since the opening between the reaction tank and the injection tank is usually narrow, when it is necessary to inject liquids such as reagents or liquids to be tested stored in the injection tank into the reaction tank, problems such as poor liquid flow or even blockage are likely to occur, resulting in a significant reduction in detection efficiency and affecting the normal use of the reagent test kit. Utility Model Content

[0003] In order to overcome the above-mentioned shortcomings of the prior art, the present disclosure aims to provide a reagent detection kit.

[0004] In order to achieve the above objectives, the present invention adopts the following technical solutions:

[0005] A reagent detection box comprises a box body and a liquid storage tank structure arranged inside the box body, wherein the liquid storage tank structure comprises a reaction tank and a plurality of liquid injection tanks, and along the circumferential direction of the reaction tank, the plurality of liquid injection tanks are arranged around the reaction tank;

[0006] The side wall of the reaction tank is provided with a plurality of openings, each of the injection tanks is connected with one of the openings, each of the openings is provided with a guide portion, the guide portion is provided on the side wall of the reaction tank, and the guide portion is configured to guide the liquid in the injection tank to flow into the reaction tank.

[0007] In a possible implementation manner, the guide portion is disposed on a side of the opening close to the bottom of the reaction tank, and the guide portion protrudes from a side wall of the reaction tank and extends toward the bottom of the reaction tank.

[0008] In a possible embodiment, a plane perpendicular to the extension direction of the guide portion is taken as the first cross-section, and the first cross-sectional area of ​​the guide portion gradually decreases along the first direction, wherein the first direction is the direction from the top of the reaction tank to the bottom of the reaction tank.

[0009] In a possible embodiment, a guide surface is further provided on the side wall of the reaction tank, and the guide surface is located below the guide portion. The side wall of the reaction tank is recessed to form the guide surface, and the guide surface extends along the first direction and is inclined in a direction away from the center of the reaction tank.

[0010] In a possible implementation, a plane along the extension direction of the guide portion and passing through a line connecting the center of the guide portion and the center of the opening is taken as the second cross section, and the second cross section of the guide portion is a right triangle or a right trapezoid.

[0011] In a possible implementation manner, the shape of the side of the guide portion away from the bottom of the reaction tank is rectangular.

[0012] In a possible implementation manner, the reaction tank and the injection tank are both circular tanks.

[0013] In a possible embodiment, the liquid storage tank structure also includes a first liquid storage cylinder and a second liquid storage cylinder, the first liquid storage cylinder is arranged above the reaction tank and the first liquid storage cylinder is connected to the reaction tank, and the second liquid storage cylinder is arranged above the injection tank and the second liquid storage cylinder is connected to the injection tank.

[0014] In a possible implementation manner, both the first liquid storage cylinder and the second liquid storage cylinder are provided with sealing plugs.

[0015] In a possible implementation manner, the sealing plug is configured as a flexible structure, or the outer side of the sealing plug is coated with a flexible layer.

[0016] The advantages of the present disclosure are that an opening and a guide portion are arranged on the side wall of the reaction tank, so that the liquid in the injection tank can pass through the opening and flow into the reaction tank along the guide portion, thereby improving the smoothness and stability of the liquid in the injection tank being injected into the reaction tank, thereby improving the overall detection efficiency and usage experience of the reagent detection box.

[0017] Other features and advantages of the present disclosure will be set forth in the subsequent description, and in part will become apparent from the description, or may be understood through implementation of the present application. The objects and other advantages of the present application may be realized and obtained through the structures particularly pointed out in the description, claims and drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] The accompanying drawings, which are incorporated into the specification and constitute a part of the specification, illustrate embodiments of the present disclosure and are used together with the description to explain the principles of the present disclosure. In these drawings, similar reference numerals are used to identify similar elements. The drawings described below are some embodiments of the present disclosure, rather than all embodiments. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without paying creative work.

[0019] Figure 1 is a schematic diagram of a reagent detection kit according to an exemplary embodiment.

[0020] Figure 2is a schematic diagram of the interior of a reagent detection box according to an exemplary embodiment.

[0021] Figure 3 is a schematic diagram of a liquid storage tank structure according to an exemplary embodiment.

[0022] Figure 4 yes Figure 3 A partial enlarged view of area A.

[0023] Figure 5 is a schematic diagram of a sealing plug according to an exemplary embodiment. DETAILED DESCRIPTION

[0024] In order to make the purpose, technical scheme and advantages of the embodiments of the present disclosure clearer, the technical scheme in the embodiments of the present disclosure will be clearly and completely described below in conjunction with the drawings in the embodiments of the present disclosure. Obviously, the described embodiments are part of the embodiments of the present disclosure, rather than all of the embodiments. Based on the embodiments of the present disclosure, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present disclosure. It should be noted that, in the absence of conflict, the embodiments in this application and the feature vectors in the embodiments can be arbitrarily combined with each other.

[0025] The reagent test kit is a commonly used detection device in the field of genetic testing, usually including a reaction tank and an injection tank connected to the reaction tank. Since the opening between the reaction tank and the injection tank is usually narrow, when it is necessary to inject liquids such as reagents or liquids to be tested stored in the injection tank into the reaction tank, problems such as poor liquid flow or even blockage are likely to occur, resulting in a significant reduction in detection efficiency and affecting the normal use of the reagent test kit.

[0026] To solve the above problems, the present disclosure provides a reagent detection box, which provides an opening and a guide portion on the side wall of the reaction tank, so that the liquid in the injection tank can pass through the opening and flow into the reaction tank along the guide portion, thereby improving the smoothness and stability of the liquid in the injection tank being injected into the reaction tank, thereby improving the overall detection efficiency and usage experience of the reagent detection box.

[0027] According to an exemplary embodiment, Figure 1-Figure 4 As shown, the embodiment of the present disclosure provides a reagent detection box, which includes a box body 10 and a liquid reservoir structure arranged inside the box body 10. The box body 10 can be made of plastic, resin, etc. The box body 10 can include an upper cover 11 and a lower cover 12, and the upper cover 11 and the lower cover 12 can be fixedly connected by bonding, plugging, snapping or other methods, wherein the liquid reservoir structure is arranged between the upper cover 11 and the lower cover 12, and the liquid reservoir structure can be arranged in the accommodating space between the upper cover 11 and the lower cover 12, and can also be at least partially arranged inside the lower cover 12.

[0028] The liquid storage tank structure includes a reaction tank 21 and a plurality of injection tanks 22. The reaction tank 21 is used to store the sample liquid to be processed, and the injection tank 22 is used to store the reagent. For example, the reagents stored in different injection tanks 22 can be the same or different. Those skilled in the art can select the quantity and type of reagents according to actual needs, and the embodiments of the present disclosure do not impose too many restrictions on this. Along the circumferential direction of the reaction tank 21, a plurality of injection tanks 22 are arranged around the reaction tank 21, and a plurality of openings 211 are also arranged on the side wall of the reaction tank 21. Each injection tank 22 is connected to an opening 211, and each opening 211 is provided with a guide 212. The guide 212 is arranged on the side wall of the reaction tank 21, and the guide 212 is arranged to guide the liquid in the injection tank 22 to flow into the reaction tank 21. When the relatively static and sealed state in the injection tank 22 is broken, for example, when positive pressure is applied to the injection tank 22 or the sealed space is opened, the liquid reagent in the injection tank 22 enters the opening 211 through the flow channel, and then the liquid is injected into the reaction tank 21 along the guide portion 212 under the action of surface tension and gravity, thereby reacting with the sample liquid in the reaction tank 21.

[0029] In the disclosed embodiment, openings and guide portions are provided on the side walls of the reaction tank so that the liquid in the injection tank can pass through the openings and flow into the reaction tank along the guide portions, thereby improving the smoothness and stability of the liquid in the injection tank being injected into the reaction tank, thereby improving the overall detection efficiency and user experience of the reagent detection box.

[0030] In some embodiments, the bottom of each injection tank 22 is connected to an opening 211 through a flow channel. In particular, the flow channel can be set as a microchannel, that is, a flow channel with a size of 1 μm to 1000 μm, which is commonly used in the field of biological gene detection.

[0031] In some embodiments, Figure 1-Figure 4 As shown, both the reaction tank 21 and the injection tank 22 are circular tanks. Since the area of ​​a circle is the largest under the same circumference, the reaction tank 21 and the injection tank 22 are set as circular tanks, so that the volume of the reaction tank 21 and the injection tank 22 can be increased as much as possible, and the circular tank is also easier to process.

[0032] In some embodiments, Figure 3-Figure 4 As shown, the guide portion 212 is disposed on one side of the opening 211 close to the bottom of the reaction tank 21, the guide portion 212 protrudes from the side wall of the reaction tank 21, and the guide portion 212 extends toward the bottom of the reaction tank 21. Figure 4 Taking the orientation shown in FIG. 2 as an example, the guide portion 212 is disposed at the lower end of the opening 211, and the guide portion 212 faces Figure 4 , so that the liquid in the liquid injection tank 22 can smoothly flow into the reaction tank 21 along the guide portion 212 .

[0033] In some embodiments, Figure 3-Figure 4 As shown in FIG. 1 , the cross-sectional area of ​​the flow guide portion 212 gradually decreases along the extension direction of the flow guide portion 212. The plane perpendicular to the extension direction of the flow guide portion 212 is the first cross-sectional area, and the direction from the top of the reaction tank 21 to the bottom of the reaction tank 21 is the first direction. The area of ​​the first cross-sectional area of ​​the flow guide portion 212 gradually decreases along the first direction. That is, Figure 4 As an example, the cross-sectional area of ​​the guide portion 212 gradually decreases from top to bottom, the top of the guide portion 212 protrudes from the side wall of the reaction tank 21, and the guide portion 212 is along the first direction (i.e. Figure 4 The guide portion 212 is formed by the liquid flowing out of the opening 211 and the guide portion 212 (as shown in the figure from top to bottom) and gradually tilts toward the side wall close to the reaction tank 21, so that the liquid flowing out of the opening 211 can flow into the reaction tank 21 as much as possible under the action of gravity, reducing the residual liquid on the guide portion 212 and avoiding excessive loss of liquid during the flow process, resulting in insufficient detection amount.

[0034] It can be understood that in the embodiment of the present disclosure, the cross-sectional area of ​​the guide portion 212 gradually decreases along the extension direction of the guide portion 212. In actual production, the shape of the guide portion 212 can also be set so that the cross-sectional area gradually increases along the extension direction of the guide portion 212. As long as the drainage effect can be achieved, the embodiment of the present disclosure does not impose too many restrictions on this.

[0035] In some embodiments, a plane along the extension direction of the guide portion 212 and passing through the line between the center of the guide portion 212 and the center of the opening 211 is the second cross section, and the shape of the second cross section of the guide portion 212 is a right triangle or a right trapezoid. Figure 4 As an example, the second section is along Figure 4 The second cross section extends from top to bottom in the reaction tank 21, and the second cross section passes through the radial direction of the flow guide 212 of the reaction tank 21. In one example, the shape of the second cross section of the flow guide 212 is a right triangle. In another example, the shape of the second cross section of the flow guide 212 is a right trapezoid.

[0036] It is worth noting that the two right-angled sides of the right triangle are respectively connected to the side wall of the reaction tank 21 and the bottom surface of the reaction tank 21, and among the three right-angled sides of the right trapezoid, the right-angled side opposite to the hypotenuse is connected to the side wall of the reaction tank 21, and the short side of the right-angled side adjacent to the hypotenuse is connected to the bottom surface of the reaction tank 21. Among them, the hypotenuse of the right triangle or the right trapezoid can be a straight line or a curve, that is, the side of the guide portion 212 facing the center of the reaction tank 21 can be a plane or a curved surface. When the hypotenuse of the right triangle or the right trapezoid is a curve, that is, the side of the guide portion 212 facing the center of the reaction tank 21 is a curved surface, by adjusting the curvature of the curved surface, the rate at which the liquid flows into the reaction tank 21 through the guide portion 212 can be adjusted, and those skilled in the art can make adjustments according to actual needs, and the embodiments of the present disclosure do not impose too many restrictions on this.

[0037] In some embodiments, Figure 4 As shown in FIG. 1 , the shape of the side of the guide portion 212 away from the bottom of the reaction tank 21 is rectangular. Figure 4 Taking the orientation shown in as an example, that is, the top surface of the guide portion 212 is a rectangle, wherein the top surface of the guide portion 212 is set to be a rectangle, which is relatively easy to process. It can be understood that the top surface of the guide portion 212 can also be set to a triangle, a semicircle or an irregular shape. The embodiment of the present disclosure does not impose too many restrictions on the shape of the side of the guide portion 212 away from the bottom of the reaction tank 21.

[0038] In some embodiments, Figure 4 As shown, the side wall of the reaction tank 21 is also provided with a guide surface 213. The guide surface 213 is located below the guide portion 212. The side wall of the reaction tank 21 is recessed to form the guide surface 213. The guide surface 213 extends along a first direction, and the guide surface 213 is inclined in a direction away from the center of the reaction tank 21. The first direction is the direction from the top of the reaction tank 21 to the bottom of the reaction tank 21. The guide portion 212 cooperates with the guide surface 213 to better guide the liquid flowing out of the injection tank 22, so that it flows into the reaction tank 21 under the action of gravity. Among them, the guide surface 213 can also avoid the mounting holes, fasteners or other structures arranged at the bottom of the reaction tank 21 while guiding the liquid. The guide surface 213 can be set as an inclined plane or an inclined curved surface, and the embodiment of the present disclosure does not impose too many restrictions on this.

[0039] In some embodiments, Figure 2-Figure 3As shown, the liquid storage tank structure also includes a first liquid storage cylinder 23 and a second liquid storage cylinder 24. The first liquid storage cylinder 23 is arranged above the reaction tank 21 and connected to the reaction tank 21, and the second liquid storage cylinder 24 is arranged above the injection tank 22 and connected to the injection tank 22. The first liquid storage cylinder 23 and the second liquid storage cylinder 24 are used to contain the liquid in the reaction tank 21 and the injection tank 22 respectively, increasing the volume while providing protection and isolation for the liquid contained therein.

[0040] In some embodiments, still referring to Figure 2-Figure 3 As shown, the first liquid storage cylinder 23 and the second liquid storage cylinder 24 are both provided with a sealing plug 25. The sealing plug 25 is used to isolate the first liquid storage cylinder 23 or the second liquid storage cylinder 24 from the external environment, so as to prevent the sample liquid or reagent from being in contact with the external environment for a long time and deteriorating, thereby reducing the detection accuracy. In addition, the sealing plug 25 can also be used to form a closed space, and due to the presence of liquid surface tension, the reagent in the liquid injection groove 22 and the reaction tank 21 remain relatively still and will not flow into the reaction tank 21, and when the sealing plug 25 is opened, the closed space is opened, and the reagent in the liquid injection groove 22 can flow into the reaction tank 21 along the guide portion 212 under the action of gravity.

[0041] In some embodiments, the sealing plug 25 is configured as a flexible structure, or the outer side of the sealing plug 25 is coated with a flexible layer. In one example, the sealing plug 25 is configured as a flexible structure, and is made of silicone, rubber or other flexible materials. Since the sealing plug 25 is a flexible structure, it can produce elastic deformation, so as to better fit with the inner wall of the first liquid storage cylinder 23 and the inner wall of the second liquid storage cylinder 24, thereby improving the sealing of the reagent detection box. In another example, the outer side of the sealing plug 25 is coated with a flexible layer 252, such as Figure 5 As shown, the sealing plug 25 includes a main body 251 and a flexible layer 252, wherein the flexible layer 252 is coated on the outside of the main body 251, wherein the main body 251 is made of hard materials such as plastic, glass, and hard resin, and the flexible layer is made of flexible materials such as silicone and rubber, which not only plays a sealing role but also has a certain degree of support, thereby facilitating the removal and insertion of the sealing plug 25.

[0042] In some embodiments, the reagent detection box may include multiple liquid storage tank structures, and different switches 30 are used to control the conduction or disconnection between the multiple liquid storage tank structures and between the liquid storage tank and the waste liquid tank to meet various sample processing requirements.

[0043] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the statement "include..." do not exclude the existence of other identical elements in the process, method, article or device comprising the elements.

[0044] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present disclosure rather than to limit it. The present disclosure is described in detail with reference to the preferred embodiments only. Those skilled in the art should understand that the technical solution of the present disclosure can be modified or replaced by equivalents without departing from the spirit and scope of the technical solution of the present disclosure, and should be included in the scope of the claims of the present disclosure.

Claims

1. A reagent detection kit, characterized in that: It comprises a box body and a liquid storage tank structure arranged inside the box body, wherein the liquid storage tank structure comprises a reaction tank and a plurality of liquid injection tanks, and along the circumferential direction of the reaction tank, the plurality of liquid injection tanks are arranged around the reaction tank; The side wall of the reaction tank is provided with a plurality of openings, each of the injection tanks is connected with one of the openings, each of the openings is provided with a guide portion, the guide portion is provided on the side wall of the reaction tank, and the guide portion is configured to guide the liquid in the injection tank to flow into the reaction tank.

2. The reagent detection kit according to claim 1, characterized in that: The guide portion is arranged on one side of the opening close to the bottom of the reaction tank, and the guide portion protrudes from the side wall of the reaction tank and extends toward the bottom of the reaction tank.

3. The reagent detection kit according to claim 2, characterized in that: Taking a plane perpendicular to the extension direction of the guide portion as the first cross-section, the first cross-sectional area of ​​the guide portion gradually decreases along the first direction, wherein the first direction is the direction from the top of the reaction tank to the bottom of the reaction tank.

4. The reagent detection kit according to claim 3, characterized in that: The side wall of the reaction tank is also provided with a guide surface, the guide surface is located below the guide portion, the side wall of the reaction tank is recessed to form the guide surface, the guide surface extends along the first direction and is inclined in a direction away from the center of the reaction tank.

5. The reagent detection kit according to claim 2, characterized in that: A plane along the extension direction of the guide portion and passing through a line connecting the center of the guide portion and the center of the opening is taken as the second cross section, and the second cross section of the guide portion is in a right triangle or a right trapezoid.

6. The reagent detection kit according to claim 2, characterized in that: The shape of the side of the guide portion away from the bottom of the reaction tank is rectangular.

7. The reagent detection kit according to any one of claims 1 to 6, characterized in that: The reaction tank and the injection tank are both circular tanks.

8. The reagent detection kit according to any one of claims 1 to 6, characterized in that: The liquid storage tank structure also includes a first liquid storage cylinder and a second liquid storage cylinder, the first liquid storage cylinder is arranged above the reaction tank and the first liquid storage cylinder is connected to the reaction tank, and the second liquid storage cylinder is arranged above the injection tank and the second liquid storage cylinder is connected to the injection tank.

9. The reagent detection kit according to claim 8, characterized in that: The first liquid storage cylinder and the second liquid storage cylinder are both provided with sealing plugs.

10. The reagent detection kit according to claim 9, characterized in that: The sealing plug is configured as a flexible structure, or the outer side of the sealing plug is covered with a flexible layer.

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