Cell culture plate and cell monitor

By setting a connecting plate with a film connection hole on the cell culture board, and using the design of the activity pole and twist spring to achieve easy disassembly, solving the problem that the existing cell culture board is not conducive to cell attachment and growth. Cell growth environment and higher flexibility.

CN222411612UActive Publication Date: 2025-01-28SHANGHAI LIUKE BROAD BEAN MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202323636953.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2023-12-28
Publication Date
2025-01-28
Estimated Expiration
2033-12-28

AI Technical Summary

Technical Problem

The grooves on the upper surface of existing cell culture plates have a rigid bottom, which is not conducive to the attachment and growth of certain cell types and limits the morphology and function of cells.

Method used

A cell culture plate is designed. The connection board with a connection hole is set to cover the training board. The internal bottom surface of the connected hole is a thin film, which provides more suitable cell attachment and growth environment. At the same time, the design of the connection board and the culture board is achieved through the design of the active pole and twist spring.

Benefits of technology

This design provides a more suitable adhesion and growth environment for cells, does not limit the morphology and functions of cells, and improves the efficiency and flexibility of cell culture through convenient connection disassembly methods.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a cell culture plate and a cell monitor, and the cell culture plate comprises a main body assembly which comprises a detector and a base arranged below the detector; the placing assembly comprises a connecting frame arranged in the center of the upper surface of the base, a set of square grooves connected to the inner sides of the upper surfaces of the two ends of the connecting frame, a set of mounting rods arranged in the square grooves and a set of movable blocks movably connected to the upper portions of the interiors of the square grooves. The cell culture plate solves the problems that a plurality of grooves are formed in the upper surface of an existing cell culture plate, the grooves are used for containing cells to be cultured, but the inner bottoms of the grooves are rigid, attachment and growth of certain cell types are not facilitated, and the shapes and functions of the cells are limited.
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Description

Technical Field

[0001] The utility model relates to the field of cell biotechnology, in particular to a cell culture plate and a cell monitoring instrument. Background Art

[0002] Cell culture refers to a method of simulating the in vivo environment (sterility, suitable temperature, pH and certain nutritional conditions, etc.) in vitro to enable cells to survive, grow, reproduce and maintain their main structures and functions. During the cell culture process, cell culture plates are required to place the cells to be cultured. At the same time, cell monitors are required to detect and observe the cell culture process.

[0003] However, it still has the following disadvantages in actual use:

[0004] The existing cell culture plate has a plurality of grooves on its upper surface for placing cells to be cultured. However, the inner bottom of the grooves has a rigid bottom, which is not conducive to the attachment and growth of certain cell types and also limits the morphology and function of the cells. Utility Model Content

[0005] Technical solutions to be solved

[0006] The utility model aims to provide a cell culture plate and a cell monitor, which solve the problem that a plurality of grooves are arranged on the upper surface of the existing cell culture plate proposed in the above background technology through connecting components and placing components. The grooves are used to place cells to be cultured, but the inner bottom of the grooves has a rigid bottom, which is not conducive to the attachment and growth of certain cell types and also limits the morphology and function of the cells.

[0007] Technical Solution

[0008] In order to solve the above technical problems, the utility model is realized by the following technical solutions:

[0009] The utility model is a cell culture plate, comprising:

[0010] The main body component includes a culture plate and a plate cover above the culture plate;

[0011] The connecting assembly includes a connecting plate sleeved on the inner upper surface of the culture plate, a plurality of connecting rods arranged at the connection between the connecting plate and the culture plate, a plurality of movable grooves arranged at the top end of each connecting rod, and a movable rod movably connected to the outer side of the movable groove.

[0012] Furthermore, a group of first movable shafts are arranged at the connection between the movable rod and the movable groove, and a round rod is arranged inside the first movable shaft, one end of the first movable shaft extends into the movable groove, and the first movable shaft is provided with a mounting groove at a corresponding position of the movable groove;

[0013] Both ends of the round rod extend into the movable groove;

[0014] Specifically, when the movable rod is placed horizontally, the connecting plate can be limited, and the connecting plate can be moved upward by hand so that the connecting plate provides an upward thrust to the movable rod, thereby causing the movable rod to rotate upward through the first movable axis. When the movable rod rotates to fit with the connecting rod, the connecting plate can be detached from the culture plate.

[0015] Furthermore, the surface of the round rod is sleeved with three torsion springs, one end of the torsion spring is connected to the movable rod and the first movable shaft, and the other end of the torsion spring is connected to one side of the movable groove;

[0016] Specifically, when the movable rod is not in use, the torsion spring limits the movable rod. When the movable rod is pushed upward or downward, the movable rod will rotate upward or downward on the first movable axis through the torsion spring, thereby causing the connecting plate to detach from the culture plate or to be connected to the culture plate.

[0017] Furthermore, the connecting rod is provided with a connecting groove at a corresponding position of the connecting plate, and a plurality of connecting holes are provided on the upper surface of the connecting plate, and the inner bottom surface of the connecting hole is a film;

[0018] The bottom end of the connecting rod extends into the interior of the culture plate, and a slot is formed at a corresponding position of the culture plate.

[0019] Specifically, a connecting groove is provided, and the diameter of the connecting groove is larger than the size of the connecting rod, so that the movable rod can pass through the connecting groove when it rotates downward; the inner bottom surface of the connecting hole is a film, which can provide a more suitable cell attachment and growth environment for cells; the connecting rod extends to the inside of the culture plate, so that the connecting rod can be placed firmly.

[0020] A cell monitoring instrument, comprising:

[0021] A main body component, including a detector and a base arranged below the detector;

[0022] The placement component includes a connection frame arranged in the center of the upper surface of the base, a group of square grooves connected to the inner side bands of the upper surfaces at both ends of the connection frame, a group of mounting rods arranged inside the square grooves, and a group of movable blocks movably connected to the upper part of the inner part of the square grooves.

[0023] Further, one end of the mounting rod extends to both sides of the culture plate, and the movable block is located above the mounting rod;

[0024] A second movable shaft is arranged outside the connection between the movable block and the square groove, and a circular groove is arranged at a corresponding position of the second movable shaft on the connection frame;

[0025] Specifically, when the culture plate is placed horizontally in the connecting frame, the mounting rod passes through the square groove. At this time, the mounting rod touches the lower inclined surface of the movable block, causing the movable block to move upward, thereby allowing the mounting rod to enter the deep part of the square groove. At this time, the front end of the movable block returns to its original position, and the movable block limits the mounting block, and the connecting frame limits the culture plate, preventing the liquid inside the culture plate from spilling due to shaking.

[0026] Furthermore, a set of limit blocks are arranged on both sides above the front end of the movable block, and the bottom surface of the limit blocks is in contact with the upper surface of the connection frame;

[0027] A set of moving grooves is arranged at the connection between the connection frame and the base, and two sets of moving blocks are arranged at the connection between the connection frame and the moving grooves;

[0028] Specifically, the limit block can prevent the movable block from entering the square groove as a whole. When the limit block is pushed upward, the front end of the movable block moves out from the square groove. The movable block is electrically connected to the movable groove and the base, so that the movable block drives the connecting frame and the culture plate inside to move in the movable groove, thereby allowing the detector to observe the culture plate more comprehensively.

[0029] Beneficial Effects

[0030] Compared with the prior art, the advantages of the present invention are:

[0031] 1. The utility model provides a connection plate with a connection hole to be connected with the culture plate, and the inner bottom surface of the connection hole is a film, which can provide a more suitable cell attachment and growth environment for cells, and at the same time, does not limit the morphology and function of the cells.

[0032] 2. Based on beneficial effect 1, a connecting rod is provided at the connection between the connecting plate and the culture plate, and a movable rod is provided at the top of the connecting rod to limit the connecting plate. When the connecting plate is taken upward, the upward thrust of the connecting plate causes the movable rod to rotate upward through the first movable axis and the torsion spring, and rotates until the movable rod is in contact with the connecting rod. At this time, the connecting rod and the movable rod can pass through the connecting groove, so that the connecting plate is separated from the culture plate.

[0033] 3. In the utility model, a movable connection frame is arranged on the upper surface of the base of the detector, and the connection frame is sleeved with the culture plate, so that the connection frame drives the culture plate to move, so that the detector can detect and observe the culture plate more comprehensively.

[0034] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0035] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0036] Figure 1 This is a schematic diagram of the overall appearance structure of the utility model;

[0037] Figure 2 This is a schematic diagram of the structure of the cell culture plate of the utility model;

[0038] Figure 3 This is a schematic diagram of the structure of the connection assembly of the utility model;

[0039] Figure 4 This is a schematic diagram of the structure of the connecting rod and the movable rod of the utility model;

[0040] Figure 5 For this utility model Figure 3 The enlarged structural diagram at A in the middle;

[0041] Figure 6 This is a schematic diagram of the structure of the components placed in the utility model;

[0042] Figure 7 For this utility model Figure 6 Schematic diagram of the cross-section structure.

[0043] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0044] 11. Culture plate; 12. Plate cover; 13. Detector; 14. Base; 21. Connecting plate; 211. Connecting groove; 212. Connecting hole; 22. Connecting rod; 221. Slot; 23. Movable groove; 24. Movable rod; 25. First movable axis; 26. Round rod; 27. Torsion spring; 28. Mounting groove; 31. Connecting frame; 311. Moving groove; 312. Moving block; 32. Square groove; 33. Mounting rod; 34. Movable block; 35. Second movable axis; 351. Round groove; 36. Limit block. DETAILED DESCRIPTION

[0045] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below with reference to the accompanying drawings.

[0046] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific implementation methods disclosed below.

[0047] In order to make the purpose, technical solution and advantages of the present invention more clear, the implementation mode of the present invention will be further described in detail below with reference to the accompanying drawings.

[0048] Embodiment 1

[0049] See also Figure 1-Figure 5 As shown, this embodiment is a cell culture plate, comprising:

[0050] The main body component includes a culture plate 11 and a plate cover 12 above the culture plate 11;

[0051] The connecting assembly includes a connecting plate 21 sleeved on the inner upper surface of the culture plate 11, a plurality of connecting rods 22 arranged at the connection between the connecting plate 21 and the culture plate 11, a plurality of movable grooves 23 arranged at the top of each connecting rod 22, and a movable rod 24 movably connected to the outer side of the movable groove 23;

[0052] A set of first movable shafts 25 are arranged at the connection between the movable rod 24 and the movable groove 23, and a round rod 26 is arranged inside the first movable shaft 25. One end of the first movable shaft 25 extends into the movable groove 23, and the first movable shaft 25 is provided with a mounting groove 28 at a corresponding position of the movable groove 23;

[0053] Both ends of the round rod 26 extend into the movable groove 23;

[0054] Three torsion springs 27 are sleeved on the surface of the round rod 26. One end of the torsion spring 27 is connected to the movable rod 24 and the first movable shaft 25, and the other end of the torsion spring 27 is connected to one side of the movable groove 23.

[0055] The connecting rod 22 is provided with a connecting groove 211 at a corresponding position of the connecting plate 21, and a plurality of connecting holes 212 are provided on the upper surface of the connecting plate 21, and the inner bottom surface of the connecting hole 212 is a film;

[0056] The bottom end of the connecting rod 22 extends into the interior of the culture plate 11, and the connecting rod 22 is provided with a slot 221 at a corresponding position of the culture plate 11;

[0057] How to use the connection component, publish the following steps:

[0058] When the assembly is in normal use, the connecting plate 21 and the culture plate 11 are sleeved together; when the connecting plate 21 needs to be disassembled, the connecting plate 21 is held and moved upward, and the upward thrust of the connecting plate 21 causes the movable rod 24 to rotate upward through the first movable shaft 25 and the torsion spring 27; when the movable rod 24 rotates to fit with the connecting rod 22, the connecting rod 22 and the movable rod 24 can move through the connecting groove 211, so that the connecting plate 21 is separated from the culture plate 11, and the connecting plate 21 is disassembled;

[0059] When using the connecting plate 21, hold the connecting plate 21 by hand, and then place the connecting plate 21 on the top of the connecting rod 22. At this time, the movable rod 24 is placed horizontally, and then the connecting plate 21 is pushed downward. The downward thrust of the connecting plate 21 causes the movable rod 24 to rotate downward. When the movable rod 24 rotates to fit with the connecting rod 22, the connecting rod 22 and the movable rod 24 pass through the connecting groove 211.

[0060] After passing through the connecting groove 211, the elastic force of the torsion spring 27 reacts on the first movable shaft 25 and the movable rod 24, so that the movable rod 24 rotates upward through the first movable shaft 25. After the rotation, the movable rod 24 is placed horizontally, so that the movable rod 24 limits the connecting plate 21.

[0061] The above steps improve your functionality.

[0062] Embodiment 2

[0063] See also Figure 1-Figure 2 , Figure 6-Figure 7 As shown, this embodiment is a cell monitoring instrument, comprising:

[0064] The main body assembly includes a detector 13 and a base 14 disposed below the detector 13;

[0065] The placement assembly includes a connection frame 31 disposed at the center of the upper surface of the base 14, a group of square grooves 32 connected to the inner side bands of the upper surfaces of both ends of the connection frame 31, a group of mounting rods 33 disposed inside the square grooves 32, and a group of movable blocks 34 movably connected to the upper part of the inner part of the square grooves 32;

[0066] One end of the mounting rod 33 extends to both sides of the culture plate 11, and the movable block 34 is located above the mounting rod 33;

[0067] A second movable shaft 35 is disposed outside the connection between the movable block 34 and the square groove 32 , and a circular groove 351 is disposed at a corresponding position of the second movable shaft 35 on the connection frame 31 ;

[0068] A set of limit blocks 36 are arranged on both sides above the front end of the movable block 34, and the bottom surface of the limit blocks 36 is in contact with the upper surface of the connecting frame 31;

[0069] A set of moving grooves 311 are provided at the connection between the connecting frame 31 and the base 14, and two sets of moving blocks 312 are provided at the connection between the connecting frame 31 and the moving grooves 311;

[0070] How to use the placed components, follow the steps below:

[0071] When the culture tray 11 is placed horizontally in the connection frame 31, the mounting rod 33 passes through the square groove 32. At this time, the mounting rod 33 touches the lower inclined surface of the movable block 34 in the square groove 32. The force of the moving mounting rod 33 causes the front end of the movable block 34 to rotate upward through the second movable shaft 35, so that the mounting rod 33 enters the deep part of the square groove 32.

[0072] After the mounting rod 33 passes through the front end of the movable block 34, the front end of the movable block 34 returns to its original position, thereby limiting the mounting rod 33 between the movable block 34 and the square groove 32, so that the movable block 34 limits the mounting rod 33, and the connecting frame 31 limits the culture plate 11, so as to prevent the culture plate 11 from shaking and causing the liquid inside to scatter;

[0073] The moving block 312, the moving groove 311 and the base 14 are electrically connected. After the culture plate 11 is placed in the connection frame 31, the moving block 312 drives the connection frame 31 and the culture plate 11 inside to move in the moving groove 311, so that the detector 13 can more comprehensively observe and detect the cell status in the culture plate 11;

[0074] The above steps improve your functionality.

[0075] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0076] Finally, it should be noted that the above description is only a preferred embodiment of the utility model and is not intended to limit the utility model. Although the utility model is described in detail with reference to the above embodiments, those skilled in the art can still modify the technical solutions recorded in the above embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.

Claims

1. A cell culture plate, characterized in that: include: A main body component, comprising a culture plate (11) and a plate cover (12) above the culture plate (11); The connection assembly comprises a connection plate (21) sleeved on the inner upper surface of a culture plate (11), a plurality of connection rods (22) arranged at the connection between the connection plate (21) and the culture plate (11), a plurality of movable grooves (23) arranged at the top end of each of the connection rods (22), and a movable rod (24) movably connected to the outer side of the movable groove (23).

2. A cell culture plate according to claim 1, characterized in that: A group of first movable shafts (25) are arranged at the connection points of the movable rod (24) and the movable groove (23), and a round rod (26) is arranged inside the first movable shaft (25), one end of the first movable shaft (25) extends into the movable groove (23), and the first movable shaft (25) is provided with a mounting groove (28) at a corresponding position of the movable groove (23); Both ends of the round rod (26) extend into the interior of the movable groove (23).

3. A cell culture plate according to claim 2, characterized in that: Three torsion springs (27) are sleeved on the surface of the round rod (26), one end of the torsion spring (27) is connected to the movable rod (24) and the first movable shaft (25), and the other end of the torsion spring (27) is connected to one side of the movable groove (23).

4. A cell culture plate according to claim 1, characterized in that: The connecting rod (22) is provided with a connecting groove (211) at a corresponding position of the connecting plate (21), and a plurality of connecting holes (212) are provided on the upper surface of the connecting plate (21), and the inner bottom surface of the connecting hole (212) is a film; The bottom end of the connecting rod (22) extends into the interior of the culture plate (11), and the connecting rod (22) is provided with a slot (221) at a corresponding position of the culture plate (11).

5. A cell monitoring instrument, characterized in that: include: A main body component, comprising a detector (13) and a base (14) disposed below the detector (13); The placement assembly comprises a connection frame (31) arranged at the center of the upper surface of the base (14), a group of square grooves (32) connected to the inner side bands of the upper surfaces at both ends of the connection frame (31), a group of mounting rods (33) arranged inside the square grooves (32), and a group of movable blocks (34) movably connected to the upper part of the inner part of the square grooves (32).

6. A cell monitoring instrument according to claim 5, characterized in that: One end of the mounting rod (33) extends to both sides of the culture plate (11), and the movable block (34) is located above the mounting rod (33); A second movable shaft (35) is arranged outside the connection between the movable block (34) and the square groove (32), and a circular groove (351) is arranged at a corresponding position of the second movable shaft (35) on the connection frame (31).

7. A cell monitoring instrument according to claim 5, characterized in that: A group of limit blocks (36) are arranged on both sides above the front end of the movable block (34), and the bottom surface of the limit blocks (36) is in contact with the upper surface of the connection frame (31); A group of movable grooves (311) are arranged at the connection between the connection frame (31) and the base (14), and two groups of movable blocks (312) are arranged at the connection between the connection frame (31) and the movable grooves (311).