Tool for testing evaporation rate

Abstract

The utility model provides a tool for an evaporation rate test, and relates to the field of evaporation rate tests. The at least two temperature circulation modules are in signal connection with the central control module; the central control module outputs different signals to the temperature circulation modules to indicate that the temperature circulation modules are in different working states, the central control module can control any number of temperature circulation modules, the temperature circulation modules work independently and do not interfere with one another, and the temperature circulation modules can work independently. Each temperature circulation module is opened or closed at any time according to needs, each temperature circulation module can provide corresponding temperatures for different evaporation rate tests, each independent temperature circulation module can achieve different evaporation rate tests, and the requirements of a large number of tests are met.

Description

Technical Field

[0001] The utility model relates to the field of evaporation rate testing, in particular to a tooling for evaporation rate testing. Background Art

[0002] Polymerase chain reaction (PCR) is a molecular biology technique used to amplify specific DNA fragments. In PCR technology, evaporation rate / water loss rate is an important detection indicator. Although the current nucleic acid detection analyzer can detect the evaporation rate / water loss rate, it also has the following defects:

[0003] First, the nucleic acid detection analyzer is provided with multiple installation areas for placing reaction tubes, and the heating components therein heat the multiple reaction tubes in the installation area synchronously and at the same temperature, so that the nucleic acid detection analyzer can only test the evaporation rate of one or a group of reaction tubes, resulting in waste of resources and idle space.

[0004] Second, the evaporation rate test lasts a long time, and other reaction tubes for evaporation rate testing cannot be added during the operation of the nucleic acid detection analyzer, which makes it difficult to meet the requirements of large-scale testing. Utility Model Content

[0005] The utility model provides a tool for evaporation rate testing, which aims to solve the problem that there is no targeted tool in the evaporation rate test, and it is difficult to implement evaporation rate tests at different temperatures, different quantities and different progresses.

[0006] In order to achieve the above object, the embodiment of the utility model provides a tool for evaporation rate testing, including:

[0007] Central control module;

[0008] Temperature cycle module, at least two of the temperature cycle module signals are connected to the central control module; the central control module outputs different:

[0009] A temperature signal for indicating the cycle temperature of the temperature cycle module and a time signal for indicating the cycle temperature duration of the temperature cycle module;

[0010] The temperature cycle module comprises a cavity, in which a heating unit for heating the reaction tube, a heat dissipation unit for dissipating heat from the cavity, a first temperature detection unit for detecting the surface temperature of the heating unit, and a second temperature detection unit for detecting the temperature inside the cavity are arranged;

[0011] The temperature signal includes a first temperature signal for indicating that the heating unit is at a first cycle temperature, a second temperature signal for indicating that the heating unit is at a second cycle temperature, and an adjustment temperature signal for indicating that the heat dissipation unit is started or stopped;

[0012] The time signal includes a first time signal and a second time signal, the time when the heating unit is at the first cycle temperature is the time indicated by the first time signal; the time when the heating unit is at the second cycle temperature is the time indicated by the second time signal;

[0013] The first temperature detection unit and the second temperature detection unit output a first detected temperature signal and a second detected temperature signal to the central control module.

[0014] Preferably, the central control module includes a control unit, and the first input terminal and the second input terminal of the control unit are connected to the output terminal signals of the first temperature detection unit and the second temperature detection unit; the first output terminal and the second output terminal of the control unit are respectively connected to the input terminal signals of the heating unit and the heat dissipation unit.

[0015] Preferably, the central control module further comprises an input unit, an output end of the input unit is signal-connected to a third input end of the control unit, and the input unit is used to input a first temperature signal, a second temperature signal, a first time signal and a second time signal.

[0016] Preferably, the central control module also includes a display unit, which is signal-connected to the control unit and is used to display the detection result of the second temperature detection unit in each temperature cycle module and the time indicated by the first time signal or the second time signal.

[0017] Preferably, the temperature cycle module comprises a first mounting plate and a second mounting plate, the first mounting plate and a plurality of the second mounting plates surround the cavity, a heat dissipation port is formed on the first mounting plate, the outlet of the heat dissipation unit is connected to the heat dissipation port, and the cavity undergoes heat convection with the outside through the heat dissipation unit;

[0018] The first mounting plate is also provided with an insertion channel for inserting the reaction tube, the heating unit is arranged on one side of the first mounting plate located in the cavity, and the two heating units are respectively located above and below the insertion channel.

[0019] Preferably, a pad is further provided in the cavity, the pad is provided on the first mounting plate, a necking channel is formed on a side of the pad facing the first mounting plate, and the necking channel is provided in the insertion channel;

[0020] A limiting unit for fixing the heating unit is arranged on a side of the backing plate facing away from the first mounting plate.

[0021] Preferably, the limiting unit comprises a limiting column and a limiting member, the two limiting columns are arranged at intervals on the left and right, the upper and lower surfaces of the limiting columns are formed with accommodating grooves, and the limiting member is used to fix the heating unit in the accommodating groove.

[0022] Preferably, the necked channel has a flat-mouthed inner contour, the upper and lower distance between the two heating units is greater than or equal to the thickness of the flat-mouthed reaction tube, and the left and right distance between the two limiting columns is greater than or equal to the width of the flat-mouthed reaction tube.

[0023] Preferably, the tooling for evaporation rate testing further comprises a mounting rack, and a plurality of the temperature cycle modules are arrayed in the mounting rack, and the heat dissipation ports of the temperature cycle modules face the same direction.

[0024] Preferably, the heating unit is a ceramic heating plate, the first temperature detection unit is a patch sensor, and the second temperature detection unit is arranged between the heating unit and the heat dissipation unit.

[0025] The above solution of the utility model has the following beneficial effects:

[0026] In the present application, the central control module can control any number of temperature cycle modules. Each temperature cycle module works independently without interfering with each other. Each temperature cycle module can be turned on or off at any time as needed, and each temperature cycle module can provide corresponding temperatures for different evaporation rate tests. Each independent temperature cycle module can realize different evaporation rate tests to meet the requirements of a large number of tests.

[0027] Other features and advantages of the present invention will be described in detail in the subsequent specific implementation section. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a schematic diagram of the utility model;

[0029] Figure 2 It is a schematic diagram of the temperature cycle module;

[0030] Figure 3 This is the internal schematic diagram of the temperature cycle module;

[0031] Figure 4 is a schematic diagram of the limit unit;

[0032] Figure 5 It is a schematic diagram of signal transmission between the central control module and the temperature circulation module.

[0033] [Description of Reference Numerals]

[0034] 1. Central control module; 11. Input unit; 12. Control unit; 13. Display unit;

[0035] 2. Temperature cycle module; 21. Heating unit; 22. Heat dissipation unit; 23. First temperature detection unit; 24. Second temperature detection unit; 25. First mounting plate; 26. Second mounting plate; 251. Heat dissipation port; 252. Insertion channel; 27. Pad; 271. Neck shrinkage channel; 28. Limiting unit; 281. Limiting column; 282. Limiting member;

[0036] 3. Placement rack. DETAILED DESCRIPTION

[0037] In order to make the technical problems to be solved, technical solutions and advantages of the present invention more clear, a detailed description will be given below in conjunction with the accompanying drawings and specific embodiments.

[0038] like Figure 1-5 As shown, the embodiment of the utility model provides a tooling for evaporation rate testing, including a central control module 1, a temperature cycle module 2 and a mounting frame 3, wherein at least two temperature cycle modules 2 are provided, and a plurality of temperature cycle modules 2 are respectively connected to the central control module 1 by signal, and the central control module 1 can send different signals to the plurality of temperature cycle modules 2 to indicate that the temperature cycle modules 2 are in different working states. The signal sent by the central control module 1 includes a temperature signal and a time signal, wherein the temperature signal is used to indicate the cycle temperature of the temperature cycle module 2, and the time signal is used to indicate the duration of the temperature cycle module 2 at the corresponding cycle temperature.

[0039] In the present application, the central control module 1 can independently control each temperature cycle module 2, so that the present application can perform multiple independent evaporation rate tests, and the change of the working state of one or several temperature cycle modules 2 does not affect the working state of other temperature cycle modules 2. In addition, each temperature cycle module 2 can provide the corresponding cycle temperature and cycle time for the evaporation rate test to meet the test requirements.

[0040] The central control module 1 includes a control unit 12. The temperature cycle module 2 includes a cavity, in which a heating unit 21, a heat dissipation unit 22, a first temperature detection unit 23 and a second temperature detection unit 24 are arranged, wherein the heating unit 21 is used to heat the reaction tube, the heat dissipation unit 22 is used to dissipate heat from the cavity, the first temperature detection unit 23 is arranged on the heating unit 21 and detects the temperature of the heating unit 21, and the second temperature detection unit 24 is used to detect the temperature in the cavity.

[0041] The first input terminal and the second input terminal of the control unit 12 are respectively connected to the output terminals of the first temperature detection unit 23 and the second temperature detection unit 24 , and the first output terminal and the second output terminal of the control unit 12 are respectively connected to the input terminals of the heating unit 21 and the heat dissipation unit 22 .

[0042] In the present embodiment, it is described that each temperature cycle module 2 cycles between two different cycle temperatures. It is understandable that each temperature cycle module 2 can also be set with three or more cycle temperatures.

[0043] The temperature signal includes a first temperature signal, a second temperature signal and an adjustment temperature signal, wherein the first temperature signal is used to indicate that the heating unit 21 operates at a first cycle temperature, the second temperature signal is used to indicate that the heating unit 21 operates at a second cycle temperature, and the adjustment temperature signal is used to indicate that the heat dissipation unit 22 starts and stops.

[0044] The first temperature detection unit 23 outputs a first detected temperature signal to the control unit 12, and the first detected temperature signal is obtained by the first temperature detection unit 23 detecting the surface temperature of the heating unit 21. The second temperature detection unit 24 outputs a second detected temperature signal to the control unit 12, and the second detected temperature signal is obtained by the second temperature detection unit 24 detecting the temperature in the cavity.

[0045] The aforementioned central control module 1 also includes an input unit 11, the output end of the input unit 11 is signal-connected to the third input end of the control unit 12, and the input unit 11 is used to input the first temperature signal, the temperature corresponding to the second temperature signal, and the time corresponding to the first time signal and the second time signal.

[0046] During operation, the temperature and time corresponding to the first temperature signal, the second temperature signal, the first time signal and the second time signal are input through the input unit 11. It is understandable that the input can be input through keys or by reading data pre-stored in a storage medium such as a USB flash drive.

[0047] The control unit 12 outputs a first temperature signal to the heating unit 21, and the heating unit 21 starts and heats up. At the same time, the first temperature detection unit 23 and the second temperature detection unit 24 respectively provide the first temperature detection signal and the second temperature detection signal to the control unit 12; when the control unit 12 learns through the first temperature detection unit 23 that the heating unit 21 is at the first circulation temperature, the heating unit 21 is maintained at the current temperature (i.e., the first circulation temperature), and then the control unit 12 learns through the second temperature detection unit 24 that the temperature in the cavity is at the first circulation temperature, and sends a first time signal to the heating unit 21, and the heating unit 21 maintains the current temperature for the time indicated by the first time signal.

[0048] When the heating unit 21 completes the time indicated by the first time signal, the control unit 12 outputs a second temperature signal to the heating unit 21. If the second cycle temperature is lower than the first cycle temperature at this time, then:

[0049] The control unit 12 sends a temperature adjustment signal to the heat dissipation unit 22, and the heat dissipation unit 22 starts working to reduce the temperature in the cavity. The heating unit 21 reduces the temperature of the surface of the heating unit 21 under the instruction of the second temperature signal. While the heating unit 21 and the heat dissipation unit 22 are working, the first temperature detection unit 23 and the second temperature detection unit 24 respectively provide the first temperature detection signal and the second temperature detection signal to the control unit 12; when the control unit 12 learns that the heating unit 21 is at the second cycle temperature through the first temperature detection unit 23, the heating unit 21 is maintained at the second cycle temperature, and then the control unit 12 learns that the temperature in the cavity is at the second cycle temperature through the second temperature detection unit 24, and sends a second time signal to the heating unit 21 and a temperature adjustment signal to the heat dissipation unit 22, and the heat dissipation unit 22 stops working, and the heating unit 21 maintains the current temperature for the time indicated by the second time signal. When the heating unit 21 completes the time indicated by the second time, the control unit 12 outputs the first temperature signal to the heating unit 21 again so that the temperature cycle module 2 cycles at the first cycle temperature and the second cycle temperature.

[0050] If the second cycle temperature is higher than the first cycle temperature at this time, then:

[0051] The control unit 12 outputs a second temperature signal to the heating unit 21, and the heating unit 21 starts and heats. At the same time, the first temperature detection unit 23 and the second temperature detection unit 24 provide the first temperature detection signal and the second temperature detection signal to the control unit 12 respectively. When the control unit 12 learns from the first temperature detection unit 23 that the heating unit 21 is at the second cycle temperature, the heating unit 21 is maintained at the second cycle temperature. Then, after the control unit 12 learns from the second temperature detection unit 24 that the temperature in the cavity is at the second cycle temperature, it sends a second time signal to the heating unit 21, and the heating unit 21 maintains the current temperature for the time indicated by the second time signal. When the heating unit 21 completes the cycle temperature duration indicated by the second time, the control unit 12 outputs the first temperature signal to the heating unit 21 again so that the temperature cycle module 2 cycles at the first cycle temperature and the second cycle temperature.

[0052] Before the heating unit 21 changes temperature to approach the first cycle temperature and the second cycle temperature, the control unit 12 controls the heating unit 21 to change at a faster rate, and when the heating unit 21 approaches the first cycle temperature and the second cycle temperature and reaches the first cycle temperature and the second cycle temperature, the heating unit 21 changes at a slower rate. The rate change is achieved by the control unit 12 using existing means.

[0053] Conventional temperature detection units only detect the temperature of the cavity or the heating unit 21. Because it takes time for heat to be transferred to the detection liquid, if only the temperature in the cavity is detected, when the cavity reaches the preset cycle temperature, the temperature of the heating unit 21 is higher than the preset cycle temperature, resulting in inaccurate actual temperature in the cavity. Similarly, if only the temperature of the heating unit 21 is detected, the actual temperature in the cavity will be slightly lower than the preset temperature, and it is impossible to know when the cavity reaches the preset temperature. Therefore, two temperature detection units are used in this application, combined with the use of the heat dissipation unit 22, to achieve precise temperature control, avoiding the actual temperature in the cavity from being inconsistent with the preset cycle temperature. At the same time, the two temperature detection units can also determine the time point when the cavity reaches the cycle temperature, and avoid including the time of cavity temperature change in the preset time, and accurately calculate the cycle time.

[0054] Furthermore, the central control module 1 further includes a display unit 13, the input end of the display unit 13 is signal-connected to the third output end of the control unit 12, and the display unit 13 is used to display the result detected by the second temperature detection unit 24 in each temperature cycle module 2 and the time indicated by the first time signal or the second time signal. There can be multiple display units 13, and the multiple display units 13 are in a one-to-one correspondence with the multiple temperature cycle modules 2. There can also be one display unit 13, and the display unit 13 is divided into multiple display areas, and the multiple display areas are in a one-to-one correspondence with the multiple temperature cycle modules 2.

[0055] In some embodiments of the present application, the temperature cycle module 2 includes a first mounting plate 25 and a second mounting plate 26, wherein a plurality of second mounting plates 26 surround a cavity with an opening, and the first mounting plate 25 is used to close the opening. In this embodiment, the cavity is rectangular. A heat dissipation port 251 is formed on the first mounting plate 25, the outlet of the heat dissipation unit 22 is connected to the heat dissipation port 251, the inlet of the heat dissipation unit 22 is connected to the cavity, and the cavity and the outside are heat-conved through the heat dissipation unit 22 to maintain the temperature stability in the cavity. Preferably, the heat dissipation unit 22 is a fan. An insertion channel 252 is also provided on the first mounting plate 25, and the insertion channel 252 is arranged perpendicular to the first mounting plate 25, and the insertion channel 252 is used for inserting the reaction tube into the cavity. The aforementioned heating unit 21 is arranged on one side of the first mounting plate 25 in the cavity, and the heating unit 21 is provided with two, and the two heating units 21 are respectively located above and below the insertion channel 252, and the aforementioned second temperature detection unit 24 is arranged on one of the heating units 21. When the reaction tube is inserted into the cavity, the two heating units 21 heat the detection liquid from both sides of the reaction tube.

[0056] Preferably, a backing plate 27 is further provided in the cavity, and the backing plate 27 is provided on the first mounting plate 25, and a necking channel 271 is formed on a side of the backing plate 27 facing the first mounting plate 25, and the necking channel 271 is used to be provided in the insertion channel 252, and a limiting unit 28 is provided on a side of the backing plate 27 away from the first mounting plate 25, and the limiting unit 28 is used to fix the heating unit 21. After the necking channel 271 is provided in the insertion channel 252, the backing plate 27 is fixed by a detachable structure such as a bolt, so as to maintain the stability of the backing plate 27 and prevent the backing plate 27 and the attached structure on the backing plate 27 from falling off.

[0057] In this embodiment, the limiting unit 28 includes a limiting column 281 and a limiting member 282. The two limiting columns 281 are arranged on the pad 27 at intervals, and a receiving groove is formed on the upper and lower surfaces of the limiting column 281. The aforementioned heating unit 21 is arranged in the limiting groove, and the heating unit 21 is fixed in the limiting groove by the limiting member 282 to prevent the heating unit 21 from shaking. Preferably, the heating unit 21 is a ceramic heating plate, and the first temperature detection unit 23 is a patch sensor, and the first temperature detection unit 23 is arranged on a side of the heating unit 21 away from the reaction tube.

[0058] Furthermore, the aforementioned constricted channel 271 has a flat-mouthed inner profile, so that the constricted channel 271 can be inserted into the flat-mouthed reaction tube. The distance between the two heating units 21 is greater than or equal to the thickness of the flat-mouthed reaction tube, and the distance between the two limiting columns 281 is greater than or equal to the width of the flat-mouthed reaction tube. The heating units 21 are arranged on both sides of the reaction tube, and can uniformly and quickly heat the detection liquid in the flat-mouthed reaction tube.

[0059] Multiple temperature cycle modules 2 are arranged in the mounting frame 3, and the first mounting plates 25 of each temperature cycle module 2 face the same direction, so that the heat dissipation ports 251 of the multiple temperature cycle modules 2 face the same direction. Preferably, the multiple temperature cycle modules 2 are arranged at intervals to prevent the temperature cycle modules 2 from being affected by the temperature of the temperature cycle modules 2 adjacent to them.

[0060] The above is a preferred embodiment of the present invention. It should be pointed out that, for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principles of the present invention. These improvements and modifications should also be regarded as the protection scope of the present invention.

Claims

1. A tool for evaporation rate testing, characterized in that: include: Central control module (1); Temperature cycle modules (2), at least two of the temperature cycle modules (2) are connected to the central control module (1) by signal; the central control module (1) outputs different signals to each of the temperature cycle modules (2): A temperature signal for indicating the cycle temperature of the temperature cycle module (2) and a time signal for indicating the cycle temperature duration of the temperature cycle module (2); Each of the temperature cycle modules (2) comprises a cavity, wherein a heating unit (21) for heating a reaction tube, a heat dissipation unit (22) for dissipating heat from the cavity, a first temperature detection unit (23) for detecting the surface temperature of the heating unit (21), and a second temperature detection unit (24) for detecting the temperature inside the cavity are arranged in the cavity; The temperature signal comprises a first temperature signal for indicating that the heating unit (21) is at a first circulation temperature, a second temperature signal for indicating that the heating unit (21) is at a second circulation temperature, and an adjustment temperature signal for indicating whether the heat dissipation unit (22) is started or stopped; The time signal comprises a first time signal and a second time signal, the time during which the heating unit (21) is at the first cycle temperature is the time indicated by the first time signal; the time during which the heating unit (21) is at the second cycle temperature is the time indicated by the second time signal; The first temperature detection unit (23) and the second temperature detection unit (24) output a first detected temperature signal and a second detected temperature signal to the central control module (1).

2. The tooling for evaporation rate testing according to claim 1, characterized in that: The central control module (1) comprises a control unit (12); a first input end and a second input end of the control unit (12) are signal-connected to output ends of the first temperature detection unit (23) and the second temperature detection unit (24); and a first output end and a second output end of the control unit (12) are signal-connected to input ends of the heating unit (21) and the heat dissipation unit (22), respectively.

3. The tooling for evaporation rate testing according to claim 2, characterized in that: The central control module (1) further comprises an input unit (11), an output end of the input unit (11) being signal-connected to a third input end of the control unit (12), and the input unit (11) being used to input the first temperature signal, the second temperature signal, the first time signal and the second time signal.

4. The tooling for evaporation rate testing according to claim 3, characterized in that: The central control module (1) further comprises a display unit (13), the display unit (13) being connected to the control unit (12) by signal, the display unit (13) being used to display the detection result of the second temperature detection unit (24) in each of the temperature circulation modules (2) and the time indicated by the first time signal or the second time signal.

5. The tooling for evaporation rate testing according to claim 1, characterized in that: The temperature cycle module (2) comprises a first mounting plate (25) and a second mounting plate (26); the first mounting plate (25) and a plurality of the second mounting plates (26) surround the cavity; a heat dissipation port (251) is formed on the first mounting plate (25); an outlet of the heat dissipation unit (22) is connected to the heat dissipation port (251); and the cavity generates heat convection with the outside through the heat dissipation unit (22); The first mounting plate (25) is also provided with an insertion channel (252) for inserting a reaction tube, the heating unit (21) is arranged on one side of the first mounting plate (25) located in the cavity, and the two heating units (21) are respectively located above and below the insertion channel (252).

6. The tool for evaporation rate testing according to claim 5, characterized in that: A backing plate (27) is also provided in the cavity, and the backing plate (27) is provided on the first mounting plate (25). A necking channel (271) is formed on a side of the backing plate (27) facing the first mounting plate (25), and the necking channel (271) is provided in the insertion channel (252); A limiting unit (28) for fixing the heating unit (21) is provided on a side of the pad (27) facing away from the first mounting plate (25).

7. The tool for evaporation rate testing according to claim 6, characterized in that: The limiting unit (28) comprises a limiting column (281) and a limiting member (282), the two limiting columns (281) are arranged at intervals on the left and right, the upper and lower surfaces of the limiting columns (281) are formed with receiving grooves, and the limiting member (282) is used to fix the heating unit (21) in the receiving groove.

8. The tool for evaporation rate testing according to claim 7, characterized in that: The necked channel (271) has a flat-mouthed inner contour, the distance between the two heating units (21) is greater than or equal to the thickness of the flat-mouthed reaction tube, and the distance between the two limiting columns (281) is greater than or equal to the width of the flat-mouthed reaction tube.

9. The tool for evaporation rate testing according to claim 5, characterized in that: The tooling for evaporation rate testing also includes a mounting frame (3), wherein a plurality of the temperature cycle modules (2) are arranged in an array in the mounting frame (3), and the heat dissipation ports (251) of the temperature cycle modules (2) face the same direction.

10. The tool for evaporation rate testing according to claim 1, characterized in that: The heating unit (21) is a ceramic heating plate, the first temperature detection unit (23) is a patch sensor, and the second temperature detection unit (24) is arranged between the heating unit (21) and the heat dissipation unit (22).

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