Detection device for gene recombinant albumin

By designing a detection device for gene recombinant albumin including a frame, a loading part, a fixing part, a capping part and a limiting part, the problem of inconvenient operation of the cuvette is solved, and the cuvette is simple to be removed and Placement improves detection efficiency.

CN222439367UActive Publication Date: 2025-02-07WUHAN KETAI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420948370.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-30
Publication Date
2025-02-07
Estimated Expiration
2034-04-30

AI Technical Summary

Technical Problem

In the existing methods for detecting the expression of gene recombinant albumin, it is inconvenient to take out the cuvette containing the sample.

Method used

设计了一种基因重组白蛋白用检测装置,包括架体、装载部、固定部、封端件和限位件,通过框架侧边开口的形式,以侧边抽拉方式操作装载部,将比色皿全部带出框架,实现比色皿取出操作简便。

Benefits of technology

Through this device, the cuvette is easily removed and placed, the operation process is simplified, and the detection efficiency is improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a detection device for gene recombinant albumin, which comprises a frame body and a fixing part, the frame body comprises a frame with an opening on the side edge, a slide way is arranged in an accommodating cavity of the frame, a connecting part and a loading part are symmetrically arranged on the frame, and the connecting part and the loading part are arranged in the accommodating cavity of the frame through the slide way. The sliding way is arranged between the loading part and the connecting part, the end sealing piece is arranged on the loading part and abuts against the frame, the limiting piece is arranged on the sliding way, the loading part is operated in a side edge drawing and pulling mode through the mode that the side edge of the frame is opened, the connecting part is connected through the fixing part, and the end sealing piece is limited to the frame. The loading part and the frame are combined to form a placing component with the closed outer sides of the cuvettes, the fixing part is operated to be separated from the connecting part, then the end sealing piece is pulled to drive the loading part to make contact with the limiting piece, all the cuvettes can be taken out of the frame, closed outer sides of the cuvettes are removed, the cuvettes are sequentially taken out, and the cuvette taking-out operation is easy and convenient.
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Description

Technical Field

[0001] The utility model relates to the field of genetic engineering detection, in particular to a detection device for gene recombinant albumin. Background Art

[0002] Human recombinant albumin is a type of protein. Albumin is a type of blood product extracted from human plasma. It is an important substance that is indispensable for maintaining life. It is used clinically to correct acute blood volume loss, treat water, electrolyte and colloid imbalance, and can also be used for acute gastrointestinal bleeding, renal dialysis and severe chronic diseases. The existing methods for detecting the expression of recombinant albumin include biochemical method, electrophoresis scanning combined with Bradford method and competitive ELISA.

[0003] Currently, the biochemical method of recombinant albumin requires a cuvette and a spectrophotometer. The sample is tested by placing the cuvette loaded with the sample into a cuvette rack, and then transferring the cuvette rack to the spectrophotometer. However, the cuvette is usually immersed in the cuvette rack and can only be operated from the top opening and the side through-holes. The process of taking out the cuvette containing the sample is very troublesome. Utility Model Content

[0004] Based on the above description, the utility model provides a detection device for genetically recombinant albumin to solve the problem of inconvenient operation of taking out a cuvette containing a sample.

[0005] The technical solution of the utility model to solve the above technical problems is as follows:

[0006] A detection device for genetically recombinant albumin, comprising:

[0007] The frame body comprises a frame with a side opening, a slideway is arranged in a cavity of the frame, and connecting parts are symmetrically arranged on the frame;

[0008] A loading part, which is arranged in the frame cavity through the slideway and is used to hold a cuvette;

[0009] a fixing portion, which is disposed between the loading portion and the connecting portion and is used to define the loading portion;

[0010] An end-sealing member, which is disposed on the loading portion and abuts against the frame;

[0011] A limiting member is arranged on the slideway and is used to limit the loading part.

[0012] On the basis of the above technical solution, the present invention can also be improved as follows.

[0013] Furthermore, the slideway is composed of steps symmetrically arranged in the frame cavity, and the loading part can be pushed into or pulled out of the frame cavity along the steps.

[0014] Furthermore, the connecting portion includes a docking hole arranged on the frame, and the frame is provided with a slot communicating with the docking hole.

[0015] Furthermore, the fixing part includes connecting columns symmetrically arranged on the loading part, and a clamping plate is arranged on the connecting column. The connecting column is aligned with the docking hole, and the clamping plate is adapted to the clamping slot.

[0016] Furthermore, the end sealing member includes a buffer member arranged on the loading portion, the buffer member is provided with an end cover, and the end cover is located on the frame opening.

[0017] Furthermore, a mounting hole is provided on the end cover, and a pull-out plate is provided in the mounting hole.

[0018] Furthermore, a sliding block is provided on the end cover.

[0019] Furthermore, the limiting member is located between the steps, a clamping strip is provided on the loading portion, and the limiting member is located on a movement path of the clamping strip.

[0020] Compared with the prior art, the technical solution of this application has the following beneficial technical effects:

[0021] The utility model provides a frame, a loading part, a fixing part, an end-sealing part and a limiting part, and operates the loading part in a side-drawing manner through the form of an opening on the side of the frame. The fixing part is connected to the connecting part, and the end-sealing part is restricted on the frame, so that the loading part and the frame are combined to form a placement component with the outer side of the cuvette closed. The fixing part is separated from the connecting part by operation, and the end-sealing part is pulled to drive the loading part to contact the limiting part, so that all the cuvettes can be taken out of the frame, the outer side of the cuvettes is released, and they are taken out in sequence, thereby realizing simple cuvette taking-out operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 A schematic diagram of the structure of a detection device for genetically recombinant albumin provided in an embodiment of the utility model;

[0023] Figure 2 for Figure 1 A structural diagram from another perspective;

[0024] Figure 3 This is a schematic diagram of the cross-sectional structure of the frame in the embodiment of the utility model;

[0025] Figure 4 This is a schematic diagram of the structure of the frame in the embodiment of the utility model;

[0026] Figure 5 This is a schematic diagram of the structure of the loading part in the embodiment of the utility model;

[0027] Figure 6 for Figure 5 The structural diagram at A in the middle;

[0028] Figure 7 This is a schematic diagram of the structure of the end-sealing member in the embodiment of the utility model;

[0029] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0030] 1. Frame; 11. Frame; 12. Slide; 13. Connecting part; 131. Docking hole; 132. Slot; 2. Loading part; 3. Fixing part; 31. Connecting column; 32. Card plate; 4. End sealing part; 41. Buffer part; 42. End cover; 43. Pull-out plate; 44. Slider; 5. Limiting part. DETAILED DESCRIPTION

[0031] In order to facilitate understanding of the present application, the present application will be described more fully below with reference to the relevant drawings. Embodiments of the present application are provided in the drawings. However, the present application can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present application more thorough and comprehensive.

[0032] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0033] It will be appreciated that spatial relationship terms such as "under", "beneath", "below", "under", "above", "above", etc., may be used herein to describe the relationship of an element or feature shown in the figures to other elements or features. It should be understood that in addition to the orientations shown in the figures, spatial relationship terms also include different orientations of the device in use and operation. For example, if the device in the accompanying drawings is flipped, the element or feature described as "under other elements" or "under it" or "under it" will be oriented as "on" the other elements or features. Therefore, the exemplary terms "under" and "under" may include both upper and lower orientations. In addition, the device may also include additional orientations (e.g., rotated 90 degrees or other orientations), and the spatial descriptors used herein are interpreted accordingly.

[0034] See also Figure 1-7A detection device for genetic recombinant albumin includes a frame 1, a loading part 2, a fixing part 3, an end cap 4 and a limiter 5. The frame 1 includes a frame 11 with a side opening, a slide 12 is arranged in the cavity of the frame 11, and a connecting part 13 is symmetrically arranged on the frame 11. The loading part 2 is arranged in the cavity of the frame 11 through the slide 12, the fixing part 3 is arranged between the loading part 2 and the connecting part 13, the end cap 4 is arranged on the loading part 2 and abuts against the frame 11, and the limiter 5 is arranged on the slide 12.

[0035] Based on the above, in this embodiment, the loading part 2 for loading the cuvette is taken and placed in a side-pulling manner through the form of the side opening of the frame 11. When testing, the end-sealing member 4 pulls the loading part 2 to slide along the slide 12 in the inner cavity of the frame 11 until the loading part 2 abuts against the limiting member 5 and stops moving. Then, the cuvettes are placed on the loading part 2 in sequence, and then the end-sealing member 4 is re-applied to drive the loading part 2 to reset. When the end-sealing member 4 abuts against the frame 11, the operating fixing part 3 is in contact with the connecting part 13, and the loading part 2 and the end-sealing member 4 are restricted on the frame 11, forming a storage component for sealing the cuvette.

[0036] After the detection, the fixing part 3 is separated from the connecting part 13, and the loading part 2 and the sealing member 4 are contacted to limit it. Then the sealing member 4 is pulled to drive the loading part 2 to contact the limiting member 5, and all the cuvettes are taken out of the frame 11, so that the cuvette can be easily taken out and placed.

[0037] See also Figure 1-7 The slide 12 is composed of steps symmetrically arranged in the cavity of the frame 11. The loading part 2 can be pushed into or pulled out of the cavity of the frame 11 along the steps. The connecting part 13 includes a docking hole 131 arranged on the frame 11. The frame 11 is provided with a card slot 132 connected to the docking hole 131. The fixing part 3 includes a connecting column 31 symmetrically arranged on the loading part 2. The connecting column 31 is provided with a card plate 32. The connecting column 31 is aligned with the docking hole 131, and the card plate 32 is adapted to the card slot 132.

[0038] The above-mentioned end sealing member 4 drives the loading part 2 to enter the frame 11, closing the open end of the frame 11, and at the same time, the other end is connected by the fixing part 3 and the connecting part 13 to restrict the loading part 2 and the end sealing member 4. In this embodiment, the docking hole 131 designed by the waist hole is adapted to the connecting column 31 and the card plate 32. The card plate 32 is mounted on the connecting column 31 and can rotate around the connecting column 31, and cooperates with the fan-shaped card slot 132. When the loading part 2 approaches the inner wall of the frame 11, the connecting column 31 and the card plate 32 pass through the docking hole 131, and then rotate into the card slot 132 by swinging the card plate 32, and are restricted in the card slot 132 by the card plate 32, and the loading part 2 and the end sealing member 4 are indirectly restricted by the connecting column 31.

[0039] To restrict the card plate 32 in the card slot 132 , a slot connected to the card slot 132 is opened on the frame 11 , and the staff can push the card plate 32 downward to disengage from the card slot 132 by reaching into the slot, and then operate the end sealing member 4 to pull the loading part 2 out of the frame 11 .

[0040] Based on the prior art, the cuvette rack is usually opened on the top and symmetrical through holes are provided on the side. The loading part 2 of this embodiment adopts a combination of a base and a partition plate to form an integral support surface at the bottom, and the other three sides are connected to the outside. The cuvette can be placed on any one side. When the loading part 2 is pushed into the frame 11, the other three sides of the loading part 2 are closed by the frame 11 to form a completely closed storage area.

[0041] See also Figure 1-7 The end sealing member 4 includes a buffer member 41 disposed on the loading portion 2 , an end cover 42 is disposed on the buffer member 41 , and the end cover 42 is located on the opening of the frame 11 .

[0042] It should be noted that when the card plate 32 enters the card slot 132, it will pull the connecting column 31 outward, thereby acting on the loading part 2 and the end sealing member 4. The end sealing member 4 abuts the frame 11. In this embodiment, the loading part 2 and the end cover 42 use a buffer member 41 made of rubber. The buffer member 41 deforms and acts on the end cover 42, so that the end cover 42 is tightly attached to the frame 11, the opening is closed, and the cuvette on the loading part 2 is stored.

[0043] Based on the end cover 42 and the frame 11 forming an outer closing component of the loading part 2, a mounting hole is opened on the end cover 42 of the present embodiment, and a pull-out plate 43 is arranged in the mounting hole, which is rotatably installed in the mounting hole by the pull-out plate 43, and the rotation position of the pull-out plate 43 connected to the mounting hole is located in the middle, so that the pull-out plate 43 flips inward on one side to contact the loading part 2, forming an open buckle mechanism, and the pull-out plate 43 can act on the end cover 42 to drive the loading part 2 to move. When the end cover 42 contacts the frame 11, the pull-out plate 43 can be pressed into the mounting hole, so that the end cover 42 is complete without protruding parts, which is convenient for placing the frame 11.

[0044] Considering that the loading part 2 slides on the slide 12, one end of the pulled-out loading part 2 is located on the slide 12, and the other end is supported by the end cover 42. Therefore, a slider 44 is provided on the end cover 42 of this embodiment. The slider 44 is installed on the supporting surface of the end cover 42 to reduce the contact area between the end cover 42 and the table surface, making it convenient for the end cover 42 to move and pull out the loading part 2.

[0045] See also Figure 1-7 The limiting member 5 is located between the ladder platforms, a clamping strip is provided on the loading portion 2, and the limiting member 5 is located on the moving path of the clamping strip.

[0046] The above-mentioned limit member 5 limits the loading part 2 from being completely withdrawn. The limit member 5 can be a combination of a rotating shaft and a protrusion, and the corresponding clamping strip is designed as an L-shaped strip. When the loading part 2 drives the clamping strip to move, the clamping strip first contacts with the limit member 5 to limit the withdrawal speed of the loading part 2. At the same time, the limit member 5 rotates with the clamping strip and moves the protrusion toward the clamping strip. Finally, the clamping strip contacts with the protrusion, and the loading part 2 stops moving. In this way, the impact of the loading part 2 with the limit member 5 is reduced to avoid the liquid in the cuvette from being stirred and leaking.

[0047] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A detection device for recombinant albumin, characterized in that: include A frame body (1) comprises a frame (11) with a side opening, a slideway (12) is arranged in a cavity of the frame (11), and connecting parts (13) are symmetrically arranged on the frame (11); A loading portion (2), which is arranged in the cavity of the frame (11) through the slideway (12) and is used to hold a cuvette; a fixing portion (3), which is arranged between the loading portion (2) and the connecting portion (13) and is used to define the loading portion (2); An end sealing member (4) is arranged on the loading portion (2) and abuts against the frame (11); A limiting member (5) is arranged on the slideway (12) and is used to limit the loading portion (2).

2. The detection device for genetically recombinant albumin according to claim 1, characterized in that: The slideway (12) is composed of steps symmetrically arranged in the cavity of the frame (11), and the loading part (2) can be pushed into or pulled out of the cavity of the frame (11) along the steps.

3. The detection device for genetically recombinant albumin according to claim 2, characterized in that: The connecting portion (13) comprises a docking hole (131) arranged on the frame (11), and the frame (11) is provided with a card slot (132) communicating with the docking hole (131).

4. The detection device for genetically recombinant albumin according to claim 3, characterized in that: The fixing portion (3) comprises a connecting column (31) symmetrically arranged on the loading portion (2), a clamping plate (32) being arranged on the connecting column (31), the connecting column (31) being aligned with the docking hole (131), and the clamping plate (32) being matched with the clamping slot (132).

5. The detection device for genetically recombinant albumin according to claim 1, characterized in that: The end-sealing member (4) comprises a buffer member (41) arranged on the loading portion (2), an end cover (42) being arranged on the buffer member (41), and the end cover (42) is located on the opening of the frame (11).

6. The detection device for genetically recombinant albumin according to claim 5, characterized in that: The end cover (42) is provided with a mounting hole, and a pull-out plate (43) is arranged in the mounting hole.

7. The detection device for genetically recombinant albumin according to claim 5, characterized in that: The end cover (42) is provided with a sliding block (44).

8. The detection device for genetically recombinant albumin according to claim 2, characterized in that: The limiting member (5) is located between the steps, a clamping strip is provided on the loading portion (2), and the limiting member (5) is located on the moving path of the clamping strip.