Bioreactor

Abstract

The utility model discloses a bioreactor which comprises a reactor main body and a cover plate connected with the reactor main body in a sealing manner, the cover plate is provided with an isolation hood and a plurality of interfaces, the cover plate is also provided with a stirring mechanism for stirring liquid in the reactor main body, one end of the stirring mechanism is connected with a stirring paddle, and the other end of the stirring mechanism is connected with a motor. And the other end of the driven force magnetic steel is fixed with the driven force magnetic steel in the isolation cover outside the cover plate, a power magnetic steel matched with the driven force magnetic steel is arranged outside the isolation cover, and the power magnetic steel is connected with a driving mechanism. Compared with the prior art, the isolation hood, the cover plate and the reactor main body are enclosed to form a sealed stirring space, the stirring mechanism is positioned in the stirring space, the driven magnetic steel and the power magnetic steel form a magnetic coupling, and the driving mechanism drives the stirring paddle to rotate through the magnetic coupling, so that the sealing property of the stirring space cannot be damaged.

Description

Technical Field

[0001] The utility model relates to the technical field of reactors, in particular to a bioreactor. Background Art

[0002] The reactor is a device for realizing a reaction process, which is widely used in the fields of chemical industry, oil refining, metallurgy, etc. The reactor is a device for realizing a reaction process, which is used to realize a liquid phase single-phase reaction process and a liquid-liquid, gas-liquid, liquid-solid, gas-liquid-solid and other multiphase reaction processes, and a stirring device is often provided in the device. The patent with the publication number CN211725752U discloses a new type of glass reactor, including: a tank body, a cover body is provided on the upper part of the tank body, and the cover body is provided with a fixing bolt through the inside, the cover body is fixedly connected to the tank body through the fixing bolt, a servo drive mechanism is provided on the upper part of the cover body, and a fixing flange is provided on the upper part of the servo drive mechanism, and the servo drive mechanism is fixed between the fixing flange and the cover body, and the power output end of the servo drive mechanism is provided with a drive shaft and a paddle is provided on the surface of the drive shaft. The drive shaft needs to pass through the cover body and be fixed to the power output end of the servo drive mechanism. Since the drive shaft is rotating, it is difficult for the tank body to be completely sealed from the external environment. Utility Model Content

[0003] The utility model provides a bioreactor, which is used to solve the problem that the existing driving shaft rotation causes the tank body and the external environment to be difficult to be completely sealed.

[0004] The utility model provides a bioreactor, comprising a reactor body and a cover plate sealedly connected to the reactor body, the cover plate being provided with an isolation cover and a plurality of interfaces, the cover plate being further provided with a stirring mechanism for stirring the liquid in the reactor body, one end of the stirring mechanism being connected with a stirring paddle, and the other end being fixed outside the cover plate to a slave magnetic steel in the isolation cover, a power magnetic steel cooperating with the slave magnetic steel being provided outside the isolation cover, and the power magnetic steel being connected to a driving mechanism.

[0005] Preferably, the stirring paddle is fixed on a stirring shaft of a stirring mechanism, and a defoaming plate is fixed on the upper end of the stirring shaft in the reactor body.

[0006] Preferably, a plurality of sawtooth-shaped protrusions are provided on the bottom of the defoaming plate.

[0007] Preferably, a bearing seat is fixed to the lower end of the isolation cover, a ceramic bearing is provided between the bearing seat and the stirring shaft, and the isolation cover is connected to the reactor body through the bearing seat.

[0008] Preferably, the isolation cover is fixed to the motor base by bolts, the driving mechanism is fixed on the motor base, and the power magnetic steel is arranged in the motor base.

[0009] Preferably, an O-ring is provided between the cover plate and the reactor body.

[0010] Preferably, a tank bracket is provided on the outer side of the reactor body, and a notch is provided on the tank bracket for the heating device to enter and exit, and the heating device is arranged on the outer wall of the reactor body.

[0011] Preferably, the tank bracket is provided with arc plates on both sides of the notch, and the arc plates protrude toward the tank bracket.

[0012] Preferably, the cover plate and the tank bracket are fixed by locking screws.

[0013] Preferably, the cover plate is provided with a microbubble ventilation pipe extending into the reactor body, and the gas outlet of the microbubble ventilation pipe is located at the bottom of the reactor body.

[0014] Compared with the prior art, in the utility model, the isolation cover, the cover plate and the reactor body enclose a sealed stirring space, the stirring mechanism is located in the stirring space, the self-magnetic steel and the power magnetic steel constitute a magnetic coupling, and the driving mechanism drives the stirring paddle to rotate through the magnetic coupling without destroying the sealing of the stirring space. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the technical solutions in the present invention or the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 It is a structural schematic diagram of the utility model;

[0017] Figure 2 It is a structural schematic diagram of the utility model from another angle;

[0018] Figure 3 It is a top view of the utility model;

[0019] Figure 4 It is a cross-sectional schematic diagram of the utility model;

[0020] Figure 5 It is a partial structural schematic diagram of the utility model;

[0021] Figure 6 for Figure 2 A magnified schematic diagram of the structure in the middle.

[0022] Reference numerals:

[0023] 1. Reactor body, 2. Cover plate, 3. Isolation cover, 4. Force magnet, 5. Power magnet, 6. Driving mechanism, 7. Defoaming plate, 071. Protrusion, 8. Bearing seat, 9. Ceramic bearing, 10. Motor seat, 11. O-ring, 12. Tank bracket, 0121. Arc plate, 0122. Notch, 13. Heating device, 14. Locking screw, 15. Microbubble ventilation pipe, 16. Tail gas condenser, 17. Pressure sensor, 18. Spare plug, 19. Four-way feeding connector, 20. Handle, 21. Stirring shaft, 22. Stirring paddle, 100. Stirring mechanism. DETAILED DESCRIPTION

[0024] In order to make the purpose, technical solution and advantages of the utility model clearer, the technical solution of the utility model will be described clearly and completely in conjunction with the drawings in the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] See attached Figure 1 and attached Figure 2 The present embodiment provides a bioreactor, comprising a reactor body 1 and a cover plate 2, the reactor body 1 and the cover plate 2 are sealed and connected, an isolation cover 3 connected to the reactor body 1 is fixed above the cover plate 2, a plurality of interfaces are provided on the cover plate 2, and a stirring mechanism 100 for stirring the liquid in the reactor body 1 is also provided on the cover plate 2, one end of the stirring mechanism 100 is connected to a stirring paddle 22, and the other end passes through the cover plate 2 and is fixed to the slave magnetic steel 4 in the isolation cover 3, a power magnetic steel 5 matched with the slave magnetic steel 4 is provided outside the isolation cover 3, the slave magnetic steel 4 and the power magnetic steel 5 constitute a magnetic coupling, the power magnetic steel 5 is connected to the driving mechanism 6, the driving mechanism 6 drives the slave magnetic steel 4 to rotate by driving the power magnetic steel 5, and the slave magnetic steel 4 then drives the stirring paddle 22 to rotate through the stirring mechanism 100. The isolation cover 3, the cover plate 2 and the reactor body 1 enclose a sealed stirring space, the stirring mechanism 100 is located in the stirring space, and the driving mechanism 6 drives the stirring paddle 22 to rotate through the magnetic coupling, which will not damage the sealing of the stirring space.

[0026] Specifically, a plurality of stirring paddles 22 may be provided as required. A small reactor body 1 may contain one stirring paddle 22 , and a large reactor body 1 may contain two or more stirring paddles 22 .

[0027] As another embodiment of the present invention: Figure 5The stirring paddle 22 is fixed on the stirring shaft 21 of the stirring mechanism 100. The stirring shaft 21 passes through the cover plate 2 and is fixed to the slave magnetic steel 4 in the isolation cover 3. A defoaming plate 7 is fixed to the upper end of the stirring shaft 21 in the reactor body 1. The driving mechanism 6 drives the stirring shaft 21 to rotate through a magnetic coupling. The defoaming plate 7 is located above the stirring paddle 22 and is used to eliminate bubbles generated during the reaction of the culture solution so that they cannot spread into the isolation cover 3.

[0028] Specifically, a plurality of sawtooth-shaped protrusions 071 are provided at the bottom of the defoaming plate 7 .

[0029] As another embodiment of the present invention: Figure 6 A bearing seat 8 is fixed at the lower end of the isolation cover 3, the bearing seat 8 is fixed on the cover plate 2, a ceramic bearing 9 is arranged between the bearing seat 8 and the stirring shaft 21, and the isolation cover 3 is connected with the reactor body 1 through the bearing seat 8. The ceramic bearing 9 is fixed on the bearing seat 8, and the stirring shaft 21 is fixed on the ceramic bearing 9.

[0030] As another embodiment of the present invention: the isolation cover 3 is fixed to the motor base 10 by bolts, the motor base 10 is arranged above the isolation cover 3, the drive mechanism 6 is fixed on the motor base 10, and the power magnet 5 is arranged in the motor base 10. Specifically, the drive mechanism 6 is a servo motor.

[0031] As another embodiment of the present invention: an O-type sealing ring 11 is provided between the cover plate 2 and the reactor body 1, and the O-type sealing ring 11 is used to seal the cover plate 2 and the reactor body 1. Specifically, the reactor body 1 is a glass jar.

[0032] As another embodiment of the present invention: Figure 4 A tank support 12 is provided on the outside of the reactor body 1, and a notch 0122 is provided on the tank support 12 for the heating device 13 to enter and exit. The heating device 13 is arranged on the outer wall of the reactor body 1. This arrangement facilitates the heating device 13 to pass through the notch 0122 and be installed on the outer wall of the reactor body 1. Specifically, the heating device 13 is a heating blanket.

[0033] Specifically, the tank bracket 12 is provided with arc plates 0121 on both sides of the notch 0122, and the arc plates 0121 protrude 071 toward the tank bracket 12. This structural design enables more of the reactor body 1 to be exposed at the notch 0122, thereby facilitating the installation of the heating device 13.

[0034] As another implementation of the present utility model: the cover plate 2 and the tank bracket 12 are fixed by locking screws 14 .

[0035] As another embodiment of the present invention: Figure 3The cover plate 2 is provided with a microbubble vent pipe 15 extending into the reactor body 1, and the gas outlet of the microbubble vent pipe 15 is located at the bottom of the reactor body 1. The microbubble vent pipe 15 is an interface on the cover plate 2, and AIR, O2, CO2, and N2 enter from the bottom of the culture solution through the microbubble vent pipe 15 in a required proportion.

[0036] Another interface on the cover plate 2 is a tail gas condenser 16 , which is used to recover the tail gas in the reactor body 1 .

[0037] Another interface on the cover plate 2 is a pressure sensor 17, which is used to detect the pressure inside the reactor body 1 so as to control the gas entry.

[0038] Some interfaces on the cover plate 2 are spare plugs 18 to facilitate customers to customize functions according to needs.

[0039] Another interface on the cover plate 2 is a four-way feed connector 19, which is used to access culture fluid, acid, alkali, etc.

[0040] Another interface on the cover plate 2 is an air inlet pipe, through which air enters the space above the liquid in the reactor body 1 .

[0041] The two interfaces on the cover plate 2 are respectively a temperature electrode and a DO electrode. The temperature electrode is used to check the liquid problem in the tank body, and the DO electrode is used to detect the dissolved oxygen content.

[0042] The two interfaces on the cover plate 2 are respectively a sampling tube and a discharge tube. The sampling tube is used to take samples out of the tank body, and the discharge tube is used to extract liquid from the tank body.

[0043] A handle 20 is fixed on the cover plate 2, and the handle 20 is provided for moving the bioreactor.

[0044] The cover plate 2 is provided with a pH electrode, which is used to detect the acid and alkali content of the culture solution in the tank.

[0045] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the utility model.

Claims

1. A bioreactor, characterized in that: The invention comprises a reactor body (1) and a cover plate (2) sealedly connected to the reactor body (1); the cover plate (2) is provided with an isolation cover (3) and a plurality of interfaces; the cover plate (2) is also provided with a stirring mechanism (100) for stirring the liquid in the reactor body (1); one end of the stirring mechanism (100) is connected to a stirring paddle (22); the other end is fixed to a slave magnetic steel (4) in the isolation cover (3) outside the cover plate (2); a power magnetic steel (5) matched with the slave magnetic steel (4) is provided outside the isolation cover (3); the power magnetic steel (5) is connected to a driving mechanism (6).

2. The bioreactor according to claim 1, characterized in that The stirring paddle (22) is fixed on the stirring shaft (21) of the stirring mechanism (100), and a defoaming plate (7) is fixed on the upper end of the stirring shaft (21) in the reactor body (1).

3. The bioreactor according to claim 2, characterized in that The bottom of the defoaming plate (7) is provided with a plurality of sawtooth-shaped protrusions (071).

4. The bioreactor according to claim 1, characterized in that A bearing seat (8) is fixed to the lower end of the isolation cover (3), a ceramic bearing (9) is provided between the bearing seat (8) and the stirring shaft (21), and the isolation cover (3) is connected to the reactor body (1) through the bearing seat (8).

5. The bioreactor according to claim 1, characterized in that The isolation cover (3) is fixed to the motor base (10) by means of bolts, the drive mechanism (6) is fixed on the motor base (10), and the power magnetic steel (5) is arranged in the motor base (10).

6. The bioreactor according to claim 1, characterized in that An O-type sealing ring (11) is provided between the cover plate (2) and the reactor body (1).

7. The bioreactor according to claim 1, characterized in that A tank support (12) is provided on the outside of the reactor body (1), and a notch (0122) is provided on the tank support (12) for the heating device (13) to enter and exit, and the heating device (13) is arranged on the outer wall of the reactor body (1).

8. The bioreactor according to claim 7, characterized in that The tank support (12) is provided with arc plates (0121) on both sides of the notch (0122), respectively, and the arc plates (0121) protrude (071) toward the tank support (12).

9. The bioreactor according to claim 8, characterized in that The cover plate (2) and the tank support (12) are fixed by means of locking screws (14).

10. The bioreactor according to claim 1, characterized in that The cover plate (2) is provided with a microbubble ventilation pipe (15) extending into the reactor body (1), and the gas outlet of the microbubble ventilation pipe (15) is located at the bottom of the reactor body (1).

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