Device for uniformly mixing luminous magnetic beads of diagnostic detection reagent

By designing a mixing mechanism in the luminescent magnetic bead mixing device and using motors and gears to drive the agitating rod to tick, the problems of small amount of magnetic beads and insufficient mixing caused by large mixing blades in the existing device are solved. It realizes efficient mixing of magnetic beads, improving the stability and use effect of the device.

CN222489807UActive Publication Date: 2025-02-18武汉玖创博生物科技有限公司
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Patent Information

Application Number
CN202421040280.4
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-14
Publication Date
2025-02-18
Estimated Expiration
2034-05-14

AI Technical Summary

Technical Problem

The existing luminescent magnetic bead mixing device has a large volume of stirring leaves, resulting in a small amount of magnetic beads. The small volume of stirring leaves leads to insufficient mixing, which affects the use effect.

Method used

A diagnostic detection reagent luminescent magnetic bead mixing device is designed, and a mixing mechanism is adopted, including a motor, gear, connecting rod and agitating rod. The gear is driven to rotate through the motor, adjust the angle of the connecting rod and agitating rod, so that the agitating rod can be performed. Toggle to efficiently mix the magnetic beads in the barrel.

Benefits of technology

Through the design of the agitating rod, the mixing efficiency is improved, the agitating range is large and the volume is small, so that the magnetic beads can be mixed more fully, and the stability and use effect of the device are improved.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of magnetic bead mixing, in particular to a diagnostic detection reagent luminous magnetic bead mixing device which comprises a working table, supporting legs are fixedly connected to four corners of the lower end of the working table, a charging barrel is arranged on the left portion of the upper end of the working table, and a supporting frame is fixedly connected to the right portion of the upper end of the working table. And the left end of the support frame is fixedly connected with a uniform mixing mechanism. According to the diagnostic detection reagent luminous magnetic bead blending device, the blending mechanism is arranged, the motor is started to work, the motor drives the first gear to rotate, under the rotation action of the first gear, the angle of the first connecting rod is adjusted, the second gear rotates under the action of the first gear, and a sliding block on the second gear slides in a sliding groove, so that the luminous magnetic beads are uniformly blended, and the luminous magnetic beads are uniformly blended. According to the magnetic bead mixing device, the angle of the first connecting rod is adjusted, the angle of the second connecting rod is adjusted, meanwhile, the stirring rod is stirred, so that magnetic beads in the charging barrel are uniformly mixed, and the uniform mixing efficiency is improved due to the fact that the stirring range of the stirring rod is large and the size of the stirring rod is small.
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Description

Technical Field

[0001] The utility model relates to the technical field of luminescent magnetic bead mixing, in particular to a luminescent magnetic bead mixing device for diagnostic detection reagents. Background Art

[0002] Luminescent magnetic beads are a kind of biosensor material used for diagnostic testing, which has high sensitivity and specificity. By measuring the content of specific molecules in the sample or the presence of specific bacteria and viruses to diagnose diseases, luminescent magnetic beads are widely used in clinical diagnosis, biomedical research, environmental monitoring and other fields. They are fast, sensitive and high-throughput, which can greatly improve the efficiency and accuracy of detection. When using luminescent magnetic beads, they need to be mixed by a mixing device. There are at least the following disadvantages in the use of existing luminescent magnetic bead mixing devices: Most of the existing mixing devices are mixed by setting a stirring rod with a stirring blade, but the stirring blade is large in size during use, resulting in a small amount of magnetic beads. The small size of the stirring blade leads to insufficient mixing, which is not conducive to use. Therefore, we introduce a diagnostic test reagent luminescent magnetic bead mixing device. Utility Model Content

[0003] The main purpose of the utility model is to provide a diagnostic test reagent luminescent magnetic bead mixing device, which can effectively solve the problems in the background technology.

[0004] In order to achieve the above purpose, the technical solution adopted by the utility model is:

[0005] A diagnostic test reagent luminescent magnetic bead mixing device comprises a workbench, wherein the four corners of the lower end of the workbench are fixedly connected to support legs, a material barrel is arranged at the left part of the upper end of the workbench, a support frame is fixedly connected to the right part of the upper end of the workbench, and a mixing mechanism is fixedly connected to the left end of the support frame.

[0006] Preferably, the mixing mechanism includes a No. 1 bracket and a No. 2 bracket, the No. 1 bracket is located on the upper part of the No. 2 bracket, the No. 1 bracket and the No. 2 bracket are arranged in parallel, the rear end of the No. 1 bracket is fixedly connected to a motor, the output end of the motor is fixedly connected to a No. 1 gear, the output end of the motor passes through the No. 1 bracket, the front end of the No. 1 gear is movably connected to a No. 1 connecting rod through a rotating shaft, the left part of the front end of the No. 2 bracket is movably connected to the No. 2 gear, the right part of the front end of the No. 2 bracket is movably connected to the No. 2 connecting rod through a rotating shaft, the left part of the front end of the No. 2 connecting rod is provided with a sliding groove, the rear end of the No. 2 connecting rod and the front end of the No. 1 connecting rod are both movably connected to a stirring rod through a rotating shaft, and the lower end of the stirring rod is convex.

[0007] Preferably, the front end of the second gear is fixedly connected with a connecting shaft, the outer front surface of the connecting shaft is fixedly connected with a lever, the front end of the lever is movably connected with a slider via a rotating shaft, the slider is a "T" shaped structure, the second gear is meshed and connected with the first gear, and the diameter of the first gear is larger than the diameter of the second gear.

[0008] Preferably, the slider is slidably connected to the slide groove.

[0009] Preferably, the No. 1 bracket and the No. 2 bracket are both fixedly connected to the support frame.

[0010] Preferably, a slot is provided on the upper end of the workbench, and the slot is adapted to the shape of the barrel.

[0011] Compared with the prior art, the utility model has the following beneficial effects:

[0012] 1. By setting the mixing mechanism, start the motor to make the motor drive the No. 1 gear to rotate. Under the rotation of the No. 1 gear, the angle of the No. 1 connecting rod is adjusted, and the No. 2 gear rotates under the action of the No. 1 gear. The slider on the No. 2 gear slides in the slide groove to adjust the angle of the No. 2 connecting rod. While the angles of the No. 2 connecting rod and the No. 1 connecting rod are adjusted, the stirring rod will be moved to mix the magnetic beads in the barrel. Since the stirring range of the stirring rod is large and the stirring rod is small, the mixing efficiency can be improved;

[0013] 2. By setting a slot on the workbench, and the slot is adapted to the shape of the barrel, after the barrel is placed in the slot, the barrel is lifted and limited, which improves the stability during mixing. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the overall structure of a diagnostic test reagent luminescent magnetic bead mixing device of the utility model;

[0015] Figure 2 This is a schematic diagram of the overall structure of a mixing mechanism of a luminescent magnetic bead mixing device for diagnostic testing reagents of the utility model;

[0016] Figure 3 This is a schematic diagram of the overall structure of the second gear of a diagnostic test reagent luminescent magnetic bead mixing device of the utility model;

[0017] Figure 4 The utility model is a schematic diagram of the overall structure of a workbench of a luminescent magnetic bead mixing device for diagnostic testing reagents.

[0018] In the figure: 1. workbench; 2. supporting legs; 3. supporting frame; 4. mixing mechanism; 5. barrel; 11. slot; 41. bracket No. 1; 42. bracket No. 2; 43. motor; 44. gear No. 1; 45. connecting rod No. 1; 46. stirring rod; 47. slide groove; 48. gear No. 2; 49. connecting rod No. 2; 481. connecting shaft; 482. lever; 483. slider. DETAILED DESCRIPTION

[0019] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0020] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0021] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0022] See also Figure 1-4 , the utility model provides a technical solution:

[0023] A diagnostic test reagent luminescent magnetic bead mixing device comprises a workbench 1, the four corners of the lower end of the workbench 1 are fixedly connected to support legs 2, a barrel 5 is arranged on the left part of the upper end of the workbench 1, a support frame 3 is fixedly connected to the right part of the upper end of the workbench 1, and a mixing mechanism 4 is fixedly connected to the left end of the support frame 3.

[0024] In this embodiment, the mixing mechanism 4 includes a No. 1 bracket 41 and a No. 2 bracket 42. The No. 1 bracket 41 is located on the upper part of the No. 2 bracket 42. The No. 1 bracket 41 and the No. 2 bracket 42 are arranged in parallel. The rear end of the No. 1 bracket 41 is fixedly connected to a motor 43, and the output end of the motor 43 is fixedly connected to a No. 1 gear 44. The output end of the motor 43 runs through the No. 1 bracket 41. The front end of the No. 1 gear 44 is movably connected to a No. 1 connecting rod 45 through a rotating shaft. The left part of the front end of the No. 2 bracket 42 is movably connected to a No. 2 gear 48. The right part of the front end of the No. 2 bracket 42 is movably connected to a No. 2 connecting rod 49 through a rotating shaft. A slide groove 47 is provided on the left part of the front end of the No. 2 connecting rod 49. The rear end of the No. 2 connecting rod 49 and the front end of the No. 1 connecting rod 45 are both movably connected to a stirring device through a rotating shaft. Rod 46, the lower end of the stirring rod 46 is convex; the front end of the No. 2 gear 48 is inserted and fixedly connected with a connecting shaft 481, the outer front of the connecting shaft 481 is fixedly connected with a lever 482, and the front end of the lever 482 is movably connected with a slider 483 through a rotating shaft, and the slider 483 is a "T"-shaped structure. The No. 2 gear 48 is meshed and connected with the No. 1 gear 44, and the diameter of the No. 1 gear 44 is larger than the diameter of the No. 2 gear 48; the slider 483 is slidably connected with the slide groove 47; the No. 1 bracket 41 and the No. 2 bracket 42 are both fixedly connected to the support frame 3; a slot 11 is opened at the upper end of the workbench 1, and the slot 11 is adapted to the shape of the barrel 5. The No. 1 bracket 41 and the No. 2 bracket 42 are both "L"-shaped structures, which are convenient for the installation and setting of the No. 2 gear 48 and the No. 1 gear 44.

[0025] It should be noted that the utility model is a luminescent magnetic bead mixing device for diagnostic detection reagents. During use, the barrel 5 containing the magnetic beads is placed in the card slot 11, and the barrel 5 is held by hand to prevent the barrel 5 from shaking. The motor 43 is started through an external control system to drive the motor 43 to drive the No. 1 gear 44 to rotate. Under the rotation of the No. 1 gear 44, the angle of the No. 1 connecting rod 45 is adjusted, and the No. 2 gear 48 rotates under the action of the No. 1 gear 44. The slider 483 on the No. 2 gear 48 slides in the slide groove 47 to adjust the angle of the No. 2 connecting rod 49. While the angles of the No. 2 connecting rod 49 and the No. 1 connecting rod 45 are adjusted, the stirring rod 46 will be moved to mix the magnetic beads in the barrel 5. Since the stirring range of the stirring rod 46 is large and the stirring rod 46 is small in size, the mixing efficiency can be improved.

[0026] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A diagnostic test reagent luminescent magnetic bead mixing device, comprising a workbench (1), characterized in that: The four corners of the lower end of the workbench (1) are fixedly connected to support legs (2), the upper left portion of the workbench (1) is provided with a barrel (5), the upper right portion of the workbench (1) is fixedly connected to a support frame (3), and the left end of the support frame (3) is fixedly connected to a mixing mechanism (4); The mixing mechanism (4) comprises a first bracket (41) and a second bracket (42), wherein the first bracket (41) is located above the second bracket (42), the first bracket (41) and the second bracket (42) are arranged in parallel, the rear end of the first bracket (41) is fixedly connected to a motor (43), the output end of the motor (43) is fixedly connected to a first gear (44), the output end of the motor (43) passes through the first bracket (41), and the front end of the first gear (44) passes through A first connecting rod (45) is movably connected to the rotating shaft, a second gear (48) is movably connected to the left front end of the second bracket (42), a second connecting rod (49) is movably connected to the right front end of the second bracket (42) through a rotating shaft, a slide groove (47) is provided on the left front end of the second connecting rod (49), a rear end of the second connecting rod (49) and a front end of the first connecting rod (45) are both movably connected to a stirring rod (46) through a rotating shaft, and the lower end of the stirring rod (46) is convex.

2. A diagnostic test reagent luminescent magnetic bead mixing device according to claim 1, characterized in that: The front end of the second gear (48) is inserted and fixedly connected with a connecting shaft (481), the front surface of the connecting shaft (481) is fixedly connected with a lever (482), the front end of the lever (482) is movably connected with a slider (483) through a rotating shaft, and the slider (483) is a "T"-shaped structure. The second gear (48) is meshed and connected with the first gear (44), and the diameter of the first gear (44) is greater than the diameter of the second gear (48).

3. A diagnostic test reagent luminescent magnetic bead mixing device according to claim 2, characterized in that: The sliding block (483) is slidably connected to the sliding groove (47).

4. A diagnostic test reagent luminescent magnetic bead mixing device according to claim 1, characterized in that: The first bracket (41) and the second bracket (42) are both fixedly connected to the support frame (3).

5. A diagnostic test reagent luminescent magnetic bead mixing device according to claim 1, characterized in that: The upper end of the workbench (1) is provided with a slot (11), and the slot (11) is adapted to the outer shape of the barrel (5).