Microneedle application patch structure

Abstract

The utility model discloses a microneedle application patch structure which comprises a flexible basement membrane, an active functional layer and a plurality of microneedles. The flexible substrate film is a flexible film; the active functional layer is combined on a first surface of the flexible substrate film; each microneedle comprises a needle bottom, a needle body and a needle tip which are integrally formed; the needle bottom is combined with the first surface of the flexible base film, the active functional layer covers the needle bottom, and the needle body and the needle tip protrude out of the surface of the active functional layer; the microneedle is of a solid structure made of a soluble high-molecular polymer. When the microneedle application sheet is used, the active functional layer and the microneedle face and are tightly attached to the surface of the skin, the microneedle can pierce the cuticle and the epidermal layer of the skin of a user to form a micropore transmission channel, and effective components permeate into the deep layer of the skin.

Description

Technical Field

[0001] The utility model relates to a skin patch, and more specifically, is a microneedle patch structure. Background Art

[0002] Traditional skin patches are applied to the skin surface so that the active ingredients on the patch can be transmitted to the inside of the skin through natural penetration. However, due to the natural barrier effect of the skin's stratum corneum, the active ingredients can only act on the stratum corneum or epidermis and are difficult to penetrate into the dermis, resulting in a low conductivity of the active ingredients. Utility Model Content

[0003] In view of the problems of traditional skin patches, the utility model proposes a microneedle patch structure, which conforms to the skin and is tightly applied to the skin, and can penetrate active ingredients into the deep layer of the skin.

[0004] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0005] A microneedle patch structure, comprising:

[0006] A flexible base film, an active functional layer, and a plurality of microneedles;

[0007] The flexible substrate film is a flexible film;

[0008] The active functional layer is bonded to a first surface of the flexible base film;

[0009] Each of the plurality of microneedles comprises an integrally formed needle base, a needle body, and a needle tip; the needle base is combined with the first surface of the flexible substrate film, the active functional layer covers the needle base, and the needle body and the needle tip protrude from the surface of the active functional layer; the microneedle is a solid structure made of a soluble high molecular polymer; a needle height is formed from the needle base to the needle tip, and the needle height is 250-300um; the ratio of the width of the needle base to the needle height is 2:1; the needle base is continuous to the needle body in a tapered shape with a gradually decreasing size, and the needle tip continues the minimum size of the needle body and maintains an equal diameter extension and is in a spike shape at the final end.

[0010] Furthermore, the ratio of the height from the needle bottom to the needle body to the height of the needle tip is 2:1.

[0011] Furthermore, the microneedles are arranged at a density of 50 to 200 needles / cm on the flexible substrate membrane. 2 .

[0012] Beneficial effects of the utility model:

[0013] The flexible base film enables the microneedle patch to conform to the skin easily and be closely attached to the skin.

[0014] Microneedle puncture is painless and does not cause bleeding. The skin will heal quickly after use, which is safe and reliable.

[0015] Microneedle patches use microneedle puncture to form microporous transmission channels on the skin, allowing active ingredients to penetrate deep into the skin.

[0016] According to the structural pattern of the microneedle, the microneedle can be firmly combined with the flexible basement membrane and can withstand the reaction force of puncturing the skin, so that it is easier to puncture the skin and reduce the probability of the microneedle breaking during the process of applying and puncturing the skin, so that the microneedle can smoothly pass through the stratum corneum and epidermis of the skin and bring the effective ingredients into the dermis. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 An enlarged partial cross-sectional view of the microneedle patch of the utility model.

[0018] Figure 2 An enlarged plan view of the microneedle of the present invention.

[0019] Figure 3 A cross-sectional schematic diagram of the microneedle patch of the utility model being applied to the skin.

[0020] 1: Microneedle patch

[0021] 10: Flexible base membrane

[0022] 11: Active functional layer

[0023] 12: Microneedling

[0024] 13: Needle bottom

[0025] 14: Needle body

[0026] 15: Needle tip

[0027] 21: Stratum corneum

[0028] 22: Epidermis

[0029] 23: Dermis

[0030] H1: Needle height

[0031] H2: height from needle bottom to needle body

[0032] H3: height of needle tip

[0033] W1: Needle base width DETAILED DESCRIPTION

[0034] In order to facilitate the explanation of the central idea of ​​the utility model in the above-mentioned new content column, it is expressed in a specific embodiment. The various objects in the embodiments are depicted according to the proportions, sizes, deformations or displacements suitable for the description, rather than being drawn according to the proportions of the actual components. In actual implementation, the type, quantity, proportion and layout of each component can be changed.

[0035] like Figure 1 and Figure 2 The utility model discloses a microneedle patch 1, which comprises a flexible base film 10, an active functional layer 11, and a plurality of microneedles 12.

[0036] The flexible base film 10 is a flexible film, and the materials selected include but are not limited to artificial fibers, natural fibers, biological fibers, and hydrophilic colloids.

[0037] The active functional layer 11 is bonded to a first surface of the flexible base film 10, and the material of the active functional layer 11 includes but is not limited to hydrophilic colloids, hyaluronic acid, collagen, Yitiaogen essential oil or its extract or a mixture thereof, and other aqueous or gel substances that can penetrate the skin. Furthermore, the active functional layer 11 is a hydrophilic material composed of hydrophilic colloids and interface active agents (Tween or Span) coated with Yitiaogen essential oil or Yitiaogen extract. The Yitiaogen refers to a substance extracted from soybean plant roots, and the soybean plant roots include but are not limited to broad-leaved soybeans (commonly known as Yitiaogen), Penghu soybeans, and creeping grass beans.

[0038] The plurality of microneedles 12, each microneedle 12 includes an integrally formed needle base 13, a needle body 14, and a needle tip 15. The needle base 13 is bonded to the first surface of the flexible substrate membrane 10, the active functional layer 11 covers the needle base 13, and the needle body 14 and the needle tip 15 protrude from the surface of the active functional layer 11. The material used to make the microneedle 12 is mainly soluble polymers, including but not limited to hydrolyzates, hyaluronic acid, collagen, hyaluronic acid, biomimetic conotoxin, or other ingredients that are effective for the skin. The microneedle 12 is a solid structure, and a needle height H1 is formed from the needle base 13 to the needle tip 15, and the needle height H1 is 250-300um. The ratio of the width W1 of the needle base 13 to the needle height H1 is 2:1. The needle base 13 is continuous to the needle body 14 and is tapered with a gradually decreasing size. The needle tip 15 continues the minimum size of the needle body 14 and extends with equal diameter and forms a spike shape at the final end. The ratio of the height H2 from the needle base 13 to the needle body 14 to the height H3 of the needle tip 15 is 2:1. The microneedles 12 are arranged at a density of 50 to 200 needles / cm on the flexible substrate 10. 2 .

[0039] like Figure 3The microneedle patch 1 is used with the active functional layer 11 and the microneedles 12 facing and closely attached to the skin surface. The microneedles 12 can pierce the stratum corneum 21 and epidermis 22 of the user's skin to form tiny holes, and the active ingredients on the active functional layer 11 and the microneedles 12 can penetrate into the dermis 23 of the skin through the tiny holes on the skin. The size of the microneedles 12 does not touch the nerve ending pain receptors of the dermis 23, so it does not cause skin pain. The microneedles 12 can dissolve in the skin and bring the active ingredients into the deep layer of the skin.

Claims

1. A microneedle patch structure, characterized in that: include: A flexible base film, an active functional layer and a plurality of microneedles; The flexible substrate film is a flexible film; The active functional layer is bonded to a first surface of the flexible base film; Each of the plurality of microneedles comprises an integrally formed needle base, a needle body, and a needle tip; the needle base is combined with the first surface of the flexible substrate membrane, the active functional layer covers the needle base, and the needle body and the needle tip protrude from the surface of the active functional layer; the microneedle is a solid structure made of a soluble high molecular polymer; a needle height is formed from the needle base to the needle tip, and the needle height is 250-300um; the ratio of the width of the needle base to the needle height is 2:1; the needle base is continuous to the needle body in a tapered shape with a gradually decreasing size, and the needle tip continues the minimum size of the needle body and maintains an equal diameter extension and is in a spike shape at the final end.

2. The microneedle patch structure according to claim 1, characterized in that: The ratio of the height from the needle bottom to the needle body to the height of the needle tip is 2:

1.

3. The microneedle patch structure according to claim 1, characterized in that: The microneedles are arranged at a density of 50 to 200 needles / cm on the flexible substrate membrane. 2 .

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