Allergen fluorescence immunoassay analyzer
By designing a combination of disinfection base, motor-driven conveyor rack and drying components in the fluorescence immunoassay, the detection error and contamination problems caused by sample residues are solved, and the automatic cleaning and drying of the sample box is realized, which improves detection efficiency and accuracy.
Patent Information
- Application Number
- CN202420388985.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-02-29
- Publication Date
- 2025-03-04
- Estimated Expiration
- 2034-02-28
AI Technical Summary
After multiple use of existing fluorescence immunoassays, sample residues may lead to detection errors and sample contamination.
A allergenic fluorescence immunoassay device is designed, which uses a disinfection base to store disinfectant water. The sample box is driven by a motor to drive the conveyor rack for detection and cleaning, and the drying component is used to realize automatic cleaning and drying of the sample box.
It effectively avoids sample contamination during reuse of sample boxes, reduces detection errors, and realizes efficient inspection of allergens in samples in batches.
Smart Images

Figure CN222561623U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of clinical medicine, in particular to an allergen fluorescent immunoassay analyzer. Background Art
[0002] Fluorescence immunoassay is a medical research instrument used in the field of clinical medicine. It is a newly developed precision immune labeling detection technology. Compared with traditional enzyme-linked immunosorbent assay and gold label method, fluorescence immunoassay has high sensitivity, strong specificity, easy operation, and does not use radioactive substances as markers. Therefore, it has the advantages of no radioactivity, stable markers, easy long-term storage, good test repeatability, fast analysis speed, small sample dosage and wide standard curve range. It is mainly used for allergen detection. In the prior art, many corresponding fluorescent immunoassay analyzers have appeared, such as CN206258440U, a fluorescent immunoassay analyzer, including a base, two supporting columns are welded on both sides of the top of the base, and a top seat is provided directly above the base, the bottom sides of the top seat are respectively welded to the tops of the supporting columns, and a slide groove is provided at the bottom of the top seat, a first movable seat is slidably installed in the slide groove, and a fluorescent analysis device is fixedly installed at the bottom of the first movable seat by bolts, a movable groove is provided at the top of the top seat, and a through hole connected to the slide groove is provided on the bottom inner wall of the movable groove, a second movable seat is slidably installed in the movable groove, and one end of a connecting rod is welded to the bottom of the second movable seat, the other end of the connecting rod is welded to the top of the first movable seat, and a motor is fixedly installed at the top of the second movable seat by bolts.
[0003] There are other existing technologies:
[0004] CN209707519U, a fluorescent immunoassay analyzer;
[0005] CN207992227U, a fluorescent immunoassay analyzer.
[0006] In order to improve the detection efficiency of the fluorescent immunoassay equipment mentioned in the above-mentioned prior art, the tool for holding samples needs to be used multiple times. After multiple uses, there will inevitably be sample residues left over from the last test on the tool. These sample residues may interfere with the samples in the current test, causing errors in the test and sample contamination. Utility Model Content
[0007] The purpose of the utility model is to provide an allergen fluorescent immunoassay analyzer to solve the problems raised in the above background technology.
[0008] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an allergen fluorescent immunoassay analyzer, comprising a disinfection base, characterized in that disinfectant water is stored inside the disinfection base, a heat insulation plate is fixedly connected to the left side of the top of the disinfection base, a detection partition is fixedly connected to the right side of the top of the disinfection base, a fluorescence analysis device is arranged on the inner side of the top of the detection partition, a fixing rod is fixedly connected between the side walls of the disinfection base, bearings are sleeved on the left and right sides of the fixing rod, a connecting rod is arranged between the two bearings, a motor is arranged on the right side of the disinfection base, the motor passes through the side wall of the disinfection base and is connected with the connecting rod, a conveying rack is arranged on the outside of the bearing, a sample box is arranged between the two conveying racks, a pin is installed through the sample box near the bottom center, and a drying component is arranged on the front side of the disinfection base.
[0009] Preferably, a guard plate is provided on the back of the drying component, a heating wire is provided on the back of the guard plate, a fan is provided on the back of the heating wire, and heat dissipation holes are provided on both sides of the heat insulation plate.
[0010] Preferably, a guide plate is provided on the back of the disinfection base, and a waste box is provided at the bottom of the guide plate.
[0011] Preferably, the fixing rods between the heat insulation plates are fixedly connected to the heat insulation plates, and the fixing rods between the detection plates are fixedly connected to the detection plates.
[0012] Preferably, the bearing and the connection between the bearing and the motor are waterproofed.
[0013] Compared with the prior art, the beneficial effects of the utility model are:
[0014] 1. The allergen fluorescence immunoassay analyzer puts the sample in the sample box above and starts two motors. The motor drives the bearings and the conveyor frame to rotate. The sample box carries the sample into the fluorescence analysis device in the detection partition for allergen detection. Samples can be placed in each sample box and lined up for detection in turn, thereby realizing batch inspection of allergens in samples.
[0015] 2. For the allergen fluorescence immunoassay analyzer, the sample box after testing is dumped into the waste box, and the sample is immersed in the disinfectant in the disinfection base along with the conveyor rack. After being disinfected by the disinfectant, it is transferred to the drying component. The fan of the drying component blows the air heated by the heating wire to dry the disinfectant, thereby cleaning the sample box, and then the sample is put into the sample box for testing again, which effectively avoids the occurrence of detection errors caused by contamination between samples when the sample box is reused. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is a schematic diagram of the structure of the utility model;
[0017] Figure 2 It is a schematic diagram of another viewing angle of the structure of the utility model;
[0018] Figure 3 This is an explosion diagram of the drying component of the utility model structure;
[0019] Figure 4 This is a longitudinal sectional view of the structure of the utility model;
[0020] Figure 5 It is a transverse cross-sectional view of the structure of the utility model.
[0021] In the figure: 1. disinfection base; 2. conveyor rack; 3. sample box; 4. fluorescence analysis equipment; 5. drying assembly; 101. heat insulation board; 102. heat dissipation hole; 103. detection partition; 104. guide plate; 105. waste box; 201. fixing rod; 202. bearing; 203. connecting rod; 204. motor; 301. latch; 501. heating wire; 502. fan; 503. guard plate. DETAILED DESCRIPTION
[0022] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0023] Example: See Figure 1 The utility model provides a technical solution: an allergen fluorescent immunoassay analyzer.
[0024] Among them, disinfectant water is stored inside the disinfection base 1, an insulation board 101 is fixedly connected to the left side of the top of the disinfection base 1, a detection partition 103 is fixedly connected to the right side of the top of the disinfection base 1, a fluorescence analysis device 4 is arranged on the inner side of the top of the detection partition 103, a fixing rod 201 is fixedly connected between the side walls of the disinfection base 1, bearings 202 are sleeved on the left and right sides of the fixing rod 201, a connecting rod 203 is arranged between the two bearings 202, a motor 204 is arranged on the right side of the disinfection base 1, the motor 204 passes through the side wall of the disinfection base 1 and is connected to the connecting rod 203, a conveying rack 2 is arranged on the outside of the bearing 202, a sample box 3 is arranged between the two conveying racks 2, a pin 301 is installed through the sample box 3 near the bottom center, and a drying component 5 is arranged on the front of the disinfection base 1.
[0025] In this embodiment, two fixing rods 201 are fixedly connected inside the disinfection base 1. The right side of the fixing rod 201 is connected to the inner wall of the disinfection base 1. A hole with a diameter larger than the fixing rod 201 is opened on the disinfection base 1 at the corresponding position on the left side, and a bearing 202 is arranged in the hole. Similarly, a bearing 202 is also sleeved at the contact position between the right fixing rod 201 and the inner wall of the disinfection base 1. The two bearings 202 are exactly the same in size and are connected by four connecting rods 203. The left bearing 202 is connected to the motor 204, and the bearing 202 is driven to rotate by the motor 204. The outer side of the bearing 202 is close to the conveying frame 2. The conveying frame 2 is made of soft material and can be bent. As the bearing 202 rotates, the two conveying frames 2 rotate, driving the sample box 3 on the conveying frame 2 to rotate clockwise. The sample box 3 is fixed to the conveying frame 2 by the latch 301 and moves with the conveying frame 2. The direction is consistent, and the sample is placed in the sample box 3 at the top front end of the instrument. As the motor 204 rotates, the conveyor frame 2 is driven by the bearing 202 to transport the sample box 3 to the detection partition 103, and the fluorescence analysis device 4 detects the sample in the sample box 3. After the detection is completed, the motor 204 continues to rotate. When the sample box 3 moves to the inner end of the disinfection base 1, it will turn over as the direction of the conveyor frame 2 changes, and immerse in the disinfectant poured into the disinfection base 1. After being soaked in the disinfectant, it rises from the front end of the disinfection base 1. The disinfectant cleans the sample box 3 and removes the remaining sample traces. The conveyor frame 2 contacts the drying component 5, and the disinfectant is removed through the drying effect of the drying component 5. Finally, the sample box 3 is turned to be placed horizontally, and the sample can continue to be placed for detection, thereby avoiding contamination of the sample by multiple uses of the sample box 3.
[0026] Among them, a protective plate 503 is arranged on the back of the drying component 5, a heating wire 501 is arranged on the back of the protective plate 503, a fan 502 is arranged on the back of the heating wire 501, and heat dissipation holes 102 are opened on both sides of the heat insulation plate 101.
[0027] In this embodiment, the heating wire 501 and the fan 502 are connected through an external power supply. The heating wire 501 generates heat to heat the surrounding air. The fan 502 blows the hot air to the surface of the sample box 3. The hot air evaporates the disinfectant water and blows the disinfectant water away from the surface of the sample box 3, so that the sample box 3 becomes dry for continued use. The protective plate 503 can prevent people from contacting the heating wire 501 and causing burns. The heat dissipation holes 102 discharge the hot air to both sides to balance the air pressure inside and outside.
[0028] A guide plate 104 is disposed on the back of the disinfection base 1 , and a waste box 105 is disposed at the bottom of the guide plate 104 .
[0029] In this embodiment, after being detected by the fluorescence analysis equipment 4, the sample box 3 continues to be transported forward through the conveying rack 2, and turns to be vertically downward after passing the first fixed rod 201. The sample in the sample box 3 falls out of the sample box 3 due to the influence of gravity, and falls into the waste box 105 after hitting the guide plate 104. The top of the guide plate 104 is an inclined surface, which is higher near the disinfection base 1 and lower far from the disinfection base 1, thereby ensuring that the sample moves forward and enters the waste box 105, which is convenient for subsequent collection and sorting.
[0030] The fixing rods 201 between the heat insulation plates 101 are fixedly connected to the heat insulation plates 101 , and the fixing rods 201 between the detection partitions 103 are fixedly connected to the detection partitions 103 .
[0031] In this embodiment, two of the four fixed rods 201 are respectively arranged in the heat insulation board 101 and the detection partition 103. The heat insulation board 101 blocks the drying component 5 from blowing hot air toward the detection partition 103. The detection partition 103 protects the fluorescence analysis equipment 4 to reduce the interference of the external environment on the detection process.
[0032] The bearing 202 and the connection between the bearing 202 and the motor 204 are waterproofed.
[0033] In this embodiment, since a large amount of disinfectant water is stored inside the disinfection base 1, the two middle and lower parts of the four fixed rods 201 together with the bearings 202 are immersed in the disinfectant water. At the same time, the motor 204 is required to drive the device to operate. Therefore, waterproof treatment is required to prevent the disinfectant water from seeping into the bearings 202 or the motor 204 and causing damage.
[0034] Working principle: put the sample in the sample box 3 at the top, start the two motors 204, the motor 204 drives the bearing 202 through the connecting rod 203, and then drives the conveyor frame 2 to rotate clockwise with the four fixed rods 201 as the axis. The sample box 3 carries the sample into the fluorescence analysis device 4 in the detection partition 103 for allergen detection. After the detection is completed, the conveyor frame 2 changes direction through the fixed rod 201 in the upper right corner, the sample box 3 faces downward, and the sample in the sample box 3 falls into the waste box 105 for recovery by gravity. Then the conveyor frame 2 passes the fixed rod 201 in the lower right corner. After turning, the sample box 3 is turned over and immersed in the disinfectant water in the disinfection base 1. After being disinfected with the disinfectant, it turns through the fixed rod 201 in the lower left corner. The conveying rack 2 drives the sample box 3 to enter the drying component 5. The fan 502 of the drying component 5 blows the air heated by the heating wire 501 to dry the disinfectant, thereby cleaning the sample box 3. Samples can be placed in each sample box 3 and queued up for testing in turn. After being discarded, the samples can be disinfected with disinfectant water and reused to avoid contamination of subsequent sample boxes 3 by the samples, thereby realizing batch inspection of allergens in the samples.
[0035] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0036] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. An allergen fluorescent immunoassay analyzer, comprising a disinfection base (1), characterized in that: Disinfection water is stored inside the disinfection base (1). A heat insulation board (101) is fixedly connected to the left side of the top of the disinfection base (1). A detection partition (103) is fixedly connected to the right side of the top of the disinfection base (1). A fluorescence analysis device (4) is arranged on the inner side of the top of the detection partition (103). A fixing rod (201) is fixedly connected between the side walls of the disinfection base (1). Bearings (202) are sleeved on the left and right sides of the fixing rod (201). A connecting rod (203) is arranged between the two bearings (202). A motor (204) is arranged on the right side of the disinfection base (1). The motor (204) passes through the side wall of the disinfection base (1) and is connected to the connecting rod (203). A conveying rack (2) is arranged outside the bearing (202). A sample box (3) is arranged between the two conveying racks (2). A latch (301) is installed through the sample box (3) near the bottom center. A drying component (5) is arranged on the front of the disinfection base (1).
2. The allergen fluorescence immunoassay analyzer according to claim 1, characterized in that: A protective plate (503) is arranged on the back of the drying component (5), a heating wire (501) is arranged on the back of the protective plate (503), a fan (502) is arranged on the back of the heating wire (501), and heat dissipation holes (102) are opened on both sides of the heat insulation plate (101).
3. The allergen fluorescence immunoassay analyzer according to claim 1, characterized in that: A guide plate (104) is arranged on the back of the disinfection base (1), and a waste box (105) is arranged on the bottom of the guide plate (104).
4. The allergen fluorescence immunoassay analyzer according to claim 1, characterized in that: The fixing rods (201) between the heat insulation plates (101) are fixedly connected to the heat insulation plates (101), and the fixing rods (201) between the detection partitions (103) are fixedly connected to the detection partitions (103).
5. The allergen fluorescence immunoassay analyzer according to claim 1, characterized in that: The bearing (202) and the connection between the bearing (202) and the motor (204) are all waterproofed.
Citation Information
Patent Citations
Fluorescence immunoassay analysis meter
CN206258440U
Fluorescence immunoassay analysis meter
CN207992227U