Device for fixing tree shrew in ophthalmic experiment visual intervention and examination operation
By designing a tree shrew fixing device for ophthalmic experiments, and using an accommodating design that connects the head fixer and the trunk fixer, the problem of difficult operation of existing equipment and lack of dedicated operating channels is solved, and the stable fixation of the tree shrew and convenient operation of ophthalmic experiments is achieved.
Patent Information
- Application Number
- CN202420431254.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-06
- Publication Date
- 2025-03-11
- Estimated Expiration
- 2034-03-06
AI Technical Summary
The existing tree shrew fixed equipment is difficult to operate, has many parts, is easy to damage, is difficult to clean, and requires repeated invasive anesthesia, which is easy to cause damage to the tree shrew and lacks special ophthalmic experimental operation channels.
A tree shrew fixing device for visual intervention and examination operations of ophthalmic experiments is designed. It adopts a housing design that connects the head fixer and the trunk fixer to achieve continuous gas anesthesia through the gas exchange channel, and an eye exposure channel and a retained hole for fixing rope are set to simplify operation and reduce human resource consumption.
It realizes stable fixation of tree shrews, reduces operation difficulty and human resource consumption, improves the comfort and safety of tree shrews, extends the service life of the equipment, and is suitable for special operations in ophthalmic experiments.
Smart Images
Figure CN222584713U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a device for fixing tree shrews in visual intervention and inspection operations in ophthalmology experiments, and belongs to the technical field of animal experimental research instruments. Background Art
[0002] Tree shrews have a developed visual system and visual features similar to those of primates. Tree shrews have five toes on both their front and rear feet, each with a developed and sharp claw, a long and pointed snout, short ears, a developed post-orbital skull that forms a bony eyeball, and a large ventricle. They are good at climbing, jumping, and agile, but are timid and easily startled, and have a strong sense of territory. When used in ophthalmology-related experiments, they are sensitive and active, easily frightened, and can cause harm to experimenters with their claws and teeth, which can lead to difficulties in related operations. It often requires multiple experimenters to fix their heads to perform ophthalmic examinations, experimental modeling, and other operations. During the operation, not only will the uneven force cause physical damage to the tree shrews, but it will also greatly reduce the utilization rate of human resources.
[0003] Previous tree shrew fixation devices mainly fix the limbs and require intraperitoneal anesthesia or tail vein anesthesia. This fixation method has been found to have certain limitations through practical operations: it is difficult to operate, has many parts, is easy to damage, and is not easy to clean. In addition, repeated invasive anesthesia can easily cause damage or even death to tree shrews.
[0004] The drawback of the existing technology is that it needs to rely on manual grasping after anesthesia. First of all, this operation consumes manpower, and because tree shrews move quickly and powerfully, they are easy to escape from the grasper's hands, resulting in a lot of time wasted. Secondly, because tree shrews have sharp claws and teeth, they are easy to injure experimenters during the grasping process. Finally, when grasping the tree shrew with both hands, there is no way to fix the tree shrew's head, and there are errors in related operations such as modeling and ophthalmic examinations.
[0005] Current tree shrew fixators mostly use the method of fixing the limbs, which is prone to escape during operation and causes great harm to the tree shrew.
[0006] Most of the existing fixed devices are used for intraperitoneal injection or tail vein injection, which are invasive operations and have low animal operation safety. The utility model can achieve continuous gas anesthesia through an original containment type fixed design, which improves the defect that non-containment type equipment is in direct contact with the external environment, which will lead to too low concentration of anesthetic drugs and fail to achieve the expected anesthetic effect.
[0007] Currently, tree shrew fixators lack a dedicated operating channel for ophthalmic experiments. And because tree shrews are afraid of light, most fixation devices choose to block the tree shrew's field of vision to avoid light and make their activities more stable. Therefore, for ophthalmic experiments that mainly study visual pathways, there is a lack of a dedicated fixation device.
[0008] Existing fixtures have many parts and components, and the process of placing the tree shrew's limbs into the fixture is more complicated. The cost is relatively high, it is difficult to clean, it cannot be applied on a large scale, and its service life is short. Utility Model Content
[0009] The utility model solves the technical problems existing in the prior art, thereby providing a device for fixing tree shrews in visual intervention and inspection operations in ophthalmology experiments.
[0010] The existing technical problems are solved by the following technical solutions: a device for fixing tree shrews in visual intervention and inspection operations in ophthalmology experiments, wherein the bottom of one end of a head fixer is open, the other end of the head fixer is connected to a trunk fixer, the head fixer and the trunk fixer are in communication, the space enclosed by the head fixer and the trunk fixer is an operation area, the head fixer is provided with a gas exchange channel, the trunk fixer is provided with an eye exposure channel, a first fixing rope reserved hole, a second fixing rope reserved hole and a third fixing rope reserved hole, and the eye exposure channels on both sides are provided. The exposed channel is distributed at the lower part of the torso fixator, and there are two first fixed rope reserved holes on the upper part of the eye exposed channel, two second fixed rope reserved holes on the upper part of the first fixed rope reserved holes, and two third fixed rope reserved holes on the upper part of the second fixed rope reserved holes. One side of the torso fixator has an axial opening, and the torso fixator plates of the axial openings on both sides have vertical convex plates, the arc plate of the operating area cover plate matches the arc plate of the torso fixator, and the plate of the operating area cover plate has a vertical concave plate, and the vertical convex plate is matched and connected with the vertical concave plate.
[0011] The outer circle radius size of the torso fixator is R40MM, the inner hole radius size of the torso fixator is R38MM, the outer circle radius size of the operating area cover is R40MM, and the inner hole radius size of the operating area cover is R38MM.
[0012] The advantages of the utility model are that the tree shrew can be firmly fixed by the rope or strap and the trunk fixer part, and the utility model adopts transparent resin material to form a nearly fully enclosed structure, which further enhances the fixing effect and prevents the tree shrew from escaping due to unexpected situations. Therefore, the utility model can completely replace manual grasping and avoid the experimenter from being scratched or bitten. In addition, regarding the problem of the tree shrew's head shaking, the utility model is designed with a special head fixer to ensure the stability of its head.
[0013] The utility model abandons the idea of fixing the limbs of the tree shrew and adopts a method of fixing the trunk to prevent the tree shrew from escaping, which not only reduces the difficulty of operation but also increases the comfort of the tree shrew.
[0014] As a containing tree shrew fixer, the utility model ensures that the tree shrew is separated from the external environment and the concentration of the anesthetic drug is guaranteed. On the other hand, the radius of the gas exchange channel is increased to ensure that the tree shrew will not escape while leaving operating space for the gas anesthesia device, so that the tree shrew can be subjected to continuous gas anesthesia.
[0015] In the present invention, in order to facilitate the conduct of ophthalmology-related experiments, an eye exposure channel is specially provided, which can realize anesthesia and ophthalmology test operations at the same time, which is more convenient.
[0016] The utility model adopts an integrated design of the torso and head holder, which avoids the cumbersome operation caused by too many parts. In addition, the overall material is transparent resin, which greatly reduces the manufacturing cost and reduces the cost. In addition, the overall shape of the utility model is cylindrical, which is easier to clean and thus can extend the service life.
[0017] The utility model adopts an integrated cylindrical design, avoids numerous parts and is easy to clean.
[0018] Beneficial effects of the utility model: the utility model is provided with a trunk fixer, which fixes the trunk of the tree shrew instead of the limbs through ropes entering the reserved holes and buckles, thereby simplifying the operation difficulty and making the relative position more stable.
[0019] The utility model has an eye operation channel on the trunk fixator, the diameter of which is consistent with the diameter of the ophthalmic examination equipment, lens barrel or visual task screen required for the experiment, and can be perfectly fitted, without the need to adjust the positions of the ophthalmic examination equipment, lens barrel or visual task screen, etc. The eye operation channel is directly opposite to the eye axis, and the eye exposure channel is better opened to complete the visual task or ophthalmic examination;
[0020] The eye operation channel can also use an eyelid speculum at the same time to prevent the tree shrew's eyelids from closing and prevent the eyelids from affecting the experiment when completing visual tasks or ophthalmic examinations.
[0021] The utility model is provided with a head fixator, which can increase the stability of the eye position of the tree shrew during an ophthalmic examination, and the curvature of the head fixator corresponds to the physiological curvature of the tree shrew, making the tree shrew feel more comfortable;
[0022] The utility model has an operation area, which can be adjusted when the tree shrew is fixed or when the body position of the tree shrew is not correct after fixation without re-fixation, and can perform operations such as intraperitoneal injection and tail vein injection;
[0023] There is space in the gas exchange channel for placing a gas anesthesia inhalation device, so that the tree shrew can inhale the volatile drugs required for the experiment while ensuring the safety of the operator and without moving the tree shrew's position.
[0024] In addition, the utility model separates the tree shrew from the outside world through transparent resin and straps to prevent the tree shrew from escaping and to prevent the tree shrew's teeth and claws from hurting the experimenter. Secondly, because the utility model is easy to operate, a single person can complete the operation of fixing the tree shrew, saving a lot of human resources.
[0025] The utility model is integrated, low in cost, has fewer parts, is not easy to damage, and adopts a physiological structure that conforms to the body curve of the tree shrew, which can reduce the pain of the tree shrew and fix the tree shrew more firmly. BRIEF DESCRIPTION OF THE DRAWINGS
[0026] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the following will briefly introduce the drawings required for the embodiments or the prior art descriptions. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. As shown in the figure:
[0027] Figure 1 It is a schematic diagram of a three-dimensional structure of the utility model.
[0028] Figure 2 This is a second schematic diagram of the three-dimensional structure of the utility model.
[0029] Figure 3 For the utility model Figure 1 Schematic diagram of the local enlarged structure at point I in the middle.
[0030] Figure 4 This is a schematic diagram of the structure of the operating area cover of the utility model.
[0031] Figure 5 For the utility model Figure 4 Schematic diagram of the local enlarged structure at II in the middle. DETAILED DESCRIPTION
[0032] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0033] Example 1: Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5As shown, a device for fixing tree shrews in visual intervention and inspection operations in ophthalmic experiments, the bottom of one end of the head fixator 1 is open, the other end of the head fixator 1 is connected to the trunk fixator 3, the head fixator 1 is communicated with the trunk fixator 3, and the space enclosed by the head fixator 1 and the trunk fixator 3 is the operation area 9.
[0034] The head fixator 1 is provided with a gas exchange channel 2, the trunk fixator 3 is provided with an eye exposure channel 4, a first fixed rope reserved hole (trunk 1) 5, a second fixed rope reserved hole (trunk 1) 6 and a third fixed rope reserved hole (trunk 3) 7, the eye exposure channels 4 on both sides are located at the lower part of the trunk fixator 3, the upper part of the eye exposure channel 4 has two first fixed rope reserved holes (trunk 1) 5, and the upper part of the first fixed rope reserved hole (trunk 1) 5 has two second fixed rope reserved holes. A fixed rope reserved hole (trunk 1) 6, two third fixed rope reserved holes (trunk 3) 7 are provided on the upper part of the second fixed rope reserved hole (trunk 1) 6, an axial opening 10 is provided on one side of the trunk fixer 3, and the plates of the trunk fixer 3 at the axial openings 10 on both sides have vertical convex plates 11, the arc plate of the operating area cover plate 8 matches the arc plate of the trunk fixer 3, the plate of the operating area cover plate 8 has a vertical concave plate 12, and the vertical convex plate 11 is matched and connected with the vertical concave plate 12.
[0035] The outer circle radius of the trunk fixator 3 is R40MM, the inner circle radius of the trunk fixator 3 is R38MM, the outer circle radius of the operation area cover 8 is R40MM, and the inner circle radius of the operation area cover 8 is R38MM.
[0036] Example 2: Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, a device for fixing tree shrews during visual intervention and inspection operations in ophthalmic experiments can be used to fix tree shrews during visual intervention and inspection operations. Under the premise of protecting the operator, the safety and stability of the tree shrews when they are fixed can be increased, and the tree shrews can be effectively prevented from shifting during the inspection and escaping the control of the operator. It is also convenient for operations such as ophthalmic disease modeling and ophthalmic inspections, and the anesthetic dose can be adjusted at any time according to the activity state of the tree shrews.
[0037] A device for fixing tree shrews in visual intervention and examination operations in ophthalmic experiments, comprising five major parts: a trunk fixator, a head fixator, a visual intervention and ophthalmic examination channel, an anesthesia channel and an operation area cover: the trunk fixator comprises two eye exposure channels on the side and six fixed rope reserved holes on the back, and an operation area at the bottom; the head fixator is fixed in front of the trunk fixator, comprises two fixed rope reserved holes on the top, and a gas exchange channel is reserved in front of the head fixator; the operation area cover exists independently and can be embedded with the operation area to achieve the purpose of closing the trunk fixator.
[0038] There is an operation area under the trunk fixator, as well as two eye exposure channels on both sides. This is convenient for related operations of ophthalmic experiments. The trunk fixator is longer than the standard tree shrew body length and is equipped with six reserved holes. This is convenient for fixing the trunk and preventing the tree shrew from escaping. A gas exchange channel is left in front of the head fixator for the tree shrew to breathe and fix the anesthesia equipment. The angle of the head fixator is set to be consistent with the physiological curvature of the tree shrew's head, making the tree shrew more comfortable on the basis of fixing the head. The curvature of the operation area and the operation area cover are consistent and can be embedded.
[0039] Example 3: Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, a device for fixing tree shrews in visual intervention and examination operations in ophthalmology experiments includes three major parts: a trunk fixator 3, a head fixator 1 and an operation area cover 8.
[0040] The head holder 1 is a hollow cylinder with a gradually increasing diameter from front to back. The head holder 1 has the same physiological curve as the tree shrew's head, so that the tree shrew's head can be just stuck into the head holder 1, which is convenient for increasing the stability of the tree shrew's head. The gas exchange channel 2 is a hole in front of the head holder 1, which can provide sufficient air for the tree shrew to survive, and because its radius is much smaller than the radius of the tree shrew's body, it is guaranteed that the tree shrew cannot escape from it. The volatile drugs that the tree shrew needs to inhale in the experiment can also be placed in the gas exchange channel 2, which is convenient for experimental operation. Since the gas exchange channel 2 is closest to the tree shrew's nasal cavity, it can ensure that the tree shrew inhales volatile drugs to the greatest extent.
[0041] The trunk fixer 3 is a hollow cylinder, which is located behind the head fixer 1 and is tightly connected to it. The trunk fixer 3 is mainly used to accommodate the trunk of the tree shrew. Eye exposure channels 4 are provided on both sides of the front section of the trunk fixer 3. The radius of the eye exposure channel is slightly larger than the radius of the eye examination equipment, lens barrel, visual task screen, etc. used to complete the visual task. The eyes of the tree shrew can be fully exposed and the eye examination equipment, lens barrel, and visual task screen can be fixed. The eyelid can also be opened by the eyelid opener to ensure that the light of the ophthalmic examination equipment, lens barrel, visual task screen, etc. is fully irradiated into the pupil. Three rows of fixed rope reserved holes are reserved above the trunk fixer 3: the first fixed rope reserved hole (trunk 1) 5, the second fixed rope reserved hole (trunk 2) 6, and the third fixed rope reserved hole (trunk 3) 7.
[0042] The method of use is as follows: each row of reserved holes for fixing ropes can be passed through linear tools such as ropes and buckles. The rope or buckle enters from the reserved holes for fixing ropes on one side and then extends from the reserved holes for fixing ropes on the other side. After the corresponding position of the tree shrew's head enters the area surrounded by the rope or buckle, the rope or buckle is tightened and knotted, and the trunk of the tree shrew can be fixed to the trunk fixer 3. An operation area 9 is provided below the trunk fixer 3. The operation area 9 is a hollowed-out area with a length consistent with the length of the trunk fixer 3, which is connected to the outside world. When the posture of the tree shrew entering the area surrounded by the rope or buckle is not correct before fixation, or when the position and posture of the tree shrew needs to be adjusted after fixation, the trunk fixer 3 can be adjusted by hand from the operation area 9. In addition, the operation area 9 can also be used for operations such as intraperitoneal injection and tail vein injection.
[0043] The shape of the operation area cover 8 is completely consistent with that of the operation area 9. Its function is to close the operation area 9 after adjusting the posture of the tree shrew or performing other operations through the operation area 9 to prevent the tree shrew from escaping therefrom.
[0044] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A device for fixing tree shrews in visual intervention and inspection operations in ophthalmology experiments, characterized in that: The bottom of one end of the head fixer is an opening, and the other end of the head fixer is connected to the torso fixer. The head fixer is communicated with the torso fixer, and the space enclosed by the head fixer and the torso fixer is an operation area. The head fixer is provided with a gas exchange channel, and the torso fixer is provided with an eye exposure channel, a first fixing rope reserved hole, a second fixing rope reserved hole and a third fixing rope reserved hole. The eye exposure channels on both sides are distributed at the lower part of the torso fixer, and the upper part of the eye exposure channel has two first fixing rope reserved holes, the upper part of the first fixing rope reserved hole has two second fixing rope reserved holes, and the upper part of the second fixing rope reserved hole has two third fixing rope reserved holes. One side of the torso fixer has an axial opening, and the plates of the torso fixer with the axial openings on both sides have vertical convex plates, the arc plate of the operation area cover plate matches the arc plate of the torso fixer, and the plate of the operation area cover plate has a vertical concave plate, and the vertical convex plate is matched and connected with the vertical concave plate.
2. The device for fixing tree shrews in visual intervention and inspection operations in ophthalmology experiments according to claim 1, characterized in that: The outer circle radius size of the torso fixator is R40MM, the inner circle radius size of the torso fixator is R38MM, the outer circle radius size of the operating area cover is R40MM, and the inner circle radius size of the operating area cover is R38MM.
3. The device for fixing tree shrews in ophthalmic experimental visual intervention and inspection operations according to claim 1, characterized in that: The head holder is a hollow cylinder with a diameter gradually increasing from front to back.