Medical intermediate evaporation and concentration device

Abstract

The utility model relates to the field of medical intermediate production, in particular to a medical intermediate evaporation and concentration device. The utility model provides a medical intermediate evaporation and concentration device which can reduce waste of medical intermediates by performing secondary evaporation and purification on the medical intermediates. A medical intermediate evaporation and concentration device comprises an evaporation tank, a heating ring, shells and a mounting frame, the shells are connected to the left and right parts of the mounting frame, the evaporation tank is connected to the inner side of the right shell, a material injection port is formed in the upper side of the front part of the evaporation tank, and the heating ring is connected between the right shell and the evaporation tank. According to the device disclosed by the utility model, heated and evaporated water vapor and a small amount of medical intermediates flow into the condenser pipe from the pipeline, are liquefied after being condensed and fall into the secondary tank, and then the heating ring on the secondary tank is started to perform secondary evaporation and purification on the liquefied medical intermediates, so that the medical intermediates can be subjected to secondary evaporation and purification; and the waste of medical intermediates is reduced.

Description

Technical Field

[0001] The utility model relates to the field of pharmaceutical intermediate production, in particular to a pharmaceutical intermediate evaporation and concentration device. Background Art

[0002] Pharmaceutical intermediates are key raw materials in the process of drug synthesis. They are chemical intermediates before the production of active pharmaceutical ingredients. Evaporation and concentration of pharmaceutical intermediates is an important step in the production process of pharmaceutical intermediates. The main purpose of evaporation and concentration is to remove solvents and increase the concentration of intermediates to facilitate subsequent synthesis or purification operations.

[0003] The existing evaporation and concentration of pharmaceutical intermediates is to pour the pharmaceutical intermediates to be purified into a heating container and evaporate the water in the pharmaceutical intermediates by heating. However, during the evaporation and concentration process of the pharmaceutical intermediates, heating may cause part of the pharmaceutical intermediates to evaporate along with the water, thus causing certain waste.

[0004] Therefore, a pharmaceutical intermediate evaporation and concentration device is now developed which can reduce the waste of pharmaceutical intermediates by performing secondary evaporation and purification on the pharmaceutical intermediates. Utility Model Content

[0005] In order to overcome the disadvantage that heating during the existing evaporation and concentration process of pharmaceutical intermediates will cause part of the pharmaceutical intermediates to evaporate together with the water, thereby causing a certain amount of waste, the utility model provides a pharmaceutical intermediate evaporation and concentration device which can reduce the waste of pharmaceutical intermediates by performing secondary evaporation and purification on the pharmaceutical intermediates.

[0006] The technical scheme of the utility model is: a pharmaceutical intermediate evaporation and concentration device, comprising an evaporation tank, a heating coil, a shell and a mounting frame, the left and right parts of the mounting frame are connected with the shell, the inner side of the right shell is connected with the evaporation tank, the upper side of the front part of the evaporation tank is provided with a material injection port, and the heating coil is connected between the right shell and the evaporation tank.

[0007] In one embodiment, a screw cap is provided on the injection port.

[0008] In one embodiment, it also includes a fixed frame, a motor, a transmission rod and a stirring blade. The fixed frame is connected to the upper side of the evaporator, the fixed frame is connected to the motor, the motor output shaft is connected to the transmission rod, the transmission rod is located inside the evaporator, and a plurality of stirring blades are connected to the transmission rod.

[0009] In one of the embodiments, it also includes a pipeline, a one-way valve, a condenser and a secondary tank. The secondary tank is connected to the inner side of the left outer shell, a heating ring is connected between the left outer shell and the secondary tank, a pipeline is connected to the upper side of the evaporator, a one-way valve is rotatably connected to the pipeline, a condenser is connected to the secondary tank feed, and the condenser is connected to the pipeline.

[0010] In one of the embodiments, a discharge pipe and a valve are also included. The discharge pipe is connected between the evaporation tank and the lower side of the secondary tank, and the left and right parts of the discharge pipe are both rotatably connected to the valve.

[0011] In one embodiment, a handle is provided on the valve.

[0012] Beneficial effects: The utility model allows the heated and evaporated water vapor and a small amount of pharmaceutical intermediates to flow from the pipeline into the condenser tube, which are liquefied and fall into the secondary tank after condensation, and then the heating ring on the secondary tank is started to perform secondary evaporation and purification on the liquefied pharmaceutical intermediates, thereby achieving the effect of reducing the waste of pharmaceutical intermediates by performing secondary evaporation and purification on the pharmaceutical intermediates. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is a three-dimensional structural schematic diagram of the utility model.

[0014] Figure 2 It is a schematic cross-sectional view of the three-dimensional structure of the utility model.

[0015] Markings in the figure are: 1-evaporation tank, 2-filling port, 3-fixed frame, 4-motor, 5-transmission rod, 6-heating ring, 7-housing, 8-mounting frame, 9-stirring blade, 10-pipeline, 11-check valve, 12-condenser, 13-secondary tank, 14-discharge pipe, 15-valve. DETAILED DESCRIPTION

[0016] The present invention is further described in detail below in conjunction with the accompanying drawings and specific implementation methods, but the protection scope and application scope of the present invention are not limited.

[0017] A pharmaceutical intermediate evaporation and concentration device, such as Figure 1 and Figure 2 As shown, it includes an evaporator 1, a heating coil 6, a shell 7 and a mounting frame 8. The left and right parts of the mounting frame 8 are connected to the shell 7. The inner side of the right shell 7 is connected to the evaporator 1. A filling port 2 is opened on the upper front side of the evaporator 1. A screw cap is provided on the filling port 2 to facilitate opening and closing the filling port 2. A heating coil 6 is connected between the right shell 7 and the evaporator 1.

[0018] like Figure 1 and Figure 2 As shown, it also includes a fixing frame 3, a motor 4, a transmission rod 5 and a stirring blade 9. The fixing frame 3 is connected to the upper side of the evaporation tank 1, the fixing frame 3 is connected to the motor 4, the transmission rod 5 is connected to the output shaft of the motor 4, the transmission rod 5 is located inside the evaporation tank 1, and a plurality of stirring blades 9 are connected to the transmission rod 5.

[0019] like Figure 1 and Figure 2As shown, it also includes a pipeline 10, a one-way valve 11, a condenser 12 and a secondary tank 13. The secondary tank 13 is connected to the inner side of the left shell 7, and a heating coil 6 is connected between the left shell 7 and the secondary tank 13. The upper side of the evaporator 1 is connected to the pipeline 10, and the one-way valve 11 is rotatably connected to the pipeline 10. The secondary tank 13 is connected to the condenser 12 at the upper side, and the condenser 12 is connected to the pipeline 10.

[0020] like Figure 1 and Figure 2 As shown, it also includes a discharge pipe 14 and a valve 15. The discharge pipe 14 is connected between the evaporator 1 and the lower side of the secondary tank 13. The left and right parts of the discharge pipe 14 are both rotatably connected to the valve 15. The valve 15 is provided with a handle for easy rotation.

[0021] When using the utility model, firstly, the mounting frame 8 is placed in the evaporation and concentration area of ​​the pharmaceutical intermediate, and then the screw cap is rotated to open, and the pharmaceutical intermediate to be concentrated is poured into the evaporation tank 1 through the injection port 2, and then the screw cap is tightened. After the pharmaceutical intermediate is poured, the heating coil 6 is started to heat the evaporation tank 1, and at the same time, the motor 4 on the fixing frame 3 is started to rotate the transmission rod 5, and the stirring blade 9 is driven to rotate to stir the pharmaceutical intermediate. During the heating process of the pharmaceutical intermediate, the one-way valve 11 is rotated to open, so that the heated and evaporated water vapor and a small amount of pharmaceutical intermediate flow from the pipeline 10 into the condenser 12, and fall into the secondary tank 13 after condensation and liquefaction, and then the heating coil 6 on the secondary tank 13 is started to perform secondary evaporation and purification on the liquefied pharmaceutical intermediate. After the concentration and purification of the pharmaceutical intermediate in the secondary tank 13 is completed, the valve 15 is rotated to open, so that the pharmaceutical intermediate in the evaporation tank 1 and the secondary tank 13 is discharged and collected from the discharge pipe 14, thereby playing the role of reducing the waste of pharmaceutical intermediates by performing secondary evaporation and purification on the pharmaceutical intermediates.

[0022] The embodiments of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above embodiments, and various changes can be made within the knowledge scope of those skilled in the art without departing from the purpose of the present invention.

Claims

1. A pharmaceutical intermediate evaporation and concentration device, characterized in that: The invention comprises an evaporation tank (1), a heating coil (6), an outer shell (7) and a mounting frame (8), wherein the left and right parts of the mounting frame (8) are both connected to the outer shell (7), the inner side of the right outer shell (7) is connected to the evaporation tank (1), the front upper side of the evaporation tank (1) is provided with a material injection port (2), and the heating coil (6) is connected between the right outer shell (7) and the evaporation tank (1); and further comprises a pipeline (10), a one-way valve (11), a condenser (12) and a secondary tank (13), the inner side of the left outer shell (7) is connected to the secondary tank (13), and the left outer shell (7) is provided with a heating coil (6). A heating coil (6) is connected between the evaporator (7) and the secondary tank (13); a pipe (10) is connected to the upper side of the evaporator (1); a one-way valve (11) is rotatably connected to the pipe (10); a condenser (12) is connected to the upper side of the secondary tank (13); the condenser (12) is connected to the pipe (10); and a discharge pipe (14) and a valve (15) are also included; a discharge pipe (14) is connected between the evaporator (1) and the lower side of the secondary tank (13); and both left and right parts of the discharge pipe (14) are rotatably connected to the valve (15).

2. A pharmaceutical intermediate evaporation and concentration device as claimed in claim 1, characterized in that: The injection port (2) is provided with a screw cap.

3. The pharmaceutical intermediate evaporation and concentration device according to claim 1, characterized in that: It also comprises a fixing frame (3), a motor (4), a transmission rod (5) and stirring blades (9); the fixing frame (3) is connected to the upper side of the evaporation tank (1); the motor (4) is connected to the fixing frame (3); the output shaft of the motor (4) is connected to the transmission rod (5); the transmission rod (5) is located inside the evaporation tank (1); and a plurality of stirring blades (9) are connected to the transmission rod (5).

4. The pharmaceutical intermediate evaporation and concentration device according to claim 1, characterized in that: The valve (15) is provided with a handle.

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