Optical lens centering device

Abstract

The utility model provides an optical lens centering device, which is used for installing an optical lens in a nucleic acid sequencing system on a lens seat, and comprises a first clamping arm and a second clamping arm which are oppositely arranged, and an elastic connecting piece for connecting the first clamping arm and the second clamping arm, the first clamping arm is provided with a first abutting surface and a second abutting surface; the second clamping arm is provided with a third abutting surface and a fourth abutting surface; wherein the first abutting surface and the third abutting surface are oppositely arranged and are used for abutting against two opposite ends of the lens seat in a one-to-one correspondence manner; the second abutting surface and the fourth abutting surface are oppositely arranged and are used for abutting against the two opposite ends of the optical lens in a one-to-one correspondence mode. The optical lens can be fixed in the lens seat of the nucleic acid sequencing system, so that an operator can quickly and accurately place and mount the optical lens.

Description

Technical Field

[0001] The present application relates to the technical field of special tools, and in particular to an optical lens centering device. Background Art

[0002] The optical lenses in the nucleic acid sequencing system can be used for high-throughput fluorescence microscopy imaging technology, which is used to analyze the base sequences in DNA or RNA fragments. The selective light transmission function of the optical lens can allow light of a specific wavelength to pass through the optical lens, so that the nucleic acid sequencing system can effectively capture and analyze the base sequence of DNA or RNA during the imaging process. Therefore, the accurate installation of the optical lens in the nucleic acid sequencing system plays an important role in the accuracy of the sequencing results. Utility Model Content

[0003] In a first aspect, the present application provides an optical lens centering device, which is used in a nucleic acid sequencing system and an optical lens is installed on a lens seat, and the optical lens centering device comprises: a first clamping arm and a second clamping arm arranged opposite to each other, and an elastic connecting member connecting the first clamping arm and the second clamping arm;

[0004] The first clamping arm has a first abutting surface and a second abutting surface; the second clamping arm has a third abutting surface and a fourth abutting surface; wherein the first abutting surface and the third abutting surface are arranged opposite to each other and are used to abut against the opposite ends of the lens seat in a one-to-one correspondence; the second abutting surface and the fourth abutting surface are arranged opposite to each other and are used to abut against the opposite ends of the optical lens in a one-to-one correspondence.

[0005] In a possible implementation manner, both ends of the leaf spring have a bending structure respectively, and each bending structure is provided with a through hole that cooperates with a corresponding threaded connector.

[0006] In a possible embodiment, a first recessed structure is provided on the second abutting surface to form a glue dispensing space between the first clamping arm and the optical lens; and a second recessed structure is provided on the fourth abutting surface to form a glue dispensing space between the first clamping arm and the optical lens.

[0007] In a possible implementation, the material hardness of the first clamping arm and the second clamping arm is less than the hardness of the optical lens.

[0008] In a possible implementation manner, the second abutting surface and the fourth abutting surface are both provided with at least one protrusion.

[0009] In a possible implementation, the optical lens centering device further includes a handle; the handle includes a first handle and a second handle, the first handle is fixed to the first clamping arm; the second handle is fixed to the second clamping arm.

[0010] In a possible implementation manner, the lens seat has a V-shaped notch; wherein a side wall of the V-shaped notch is used to support the optical lens;

[0011] The first clamping arm and the second clamping arm both abut against a first support arm on one side wall of the V-shaped notch, and abut against a second support arm on the other side wall of the V-shaped notch; the first support arm is fixedly connected to the second support arm;

[0012] The first abutting surface and the second abutting surface of the first clamping arm are located on the second support arm of the first clamping arm;

[0013] The third abutting surface and the fourth abutting surface of the second clamping arm are located on the second supporting arm of the second abutting surface.

[0014] In a possible implementation manner, the first clamping arm has a fifth abutting surface for abutting against the lens seat, and the fifth abutting surface is connected to the second abutting surface to form an L-shaped surface;

[0015] The second clamping arm has a sixth abutting surface for abutting against the lens seat, and the fifth abutting surface is connected to the fourth abutting surface to form an L-shaped surface.

[0016] In a possible implementation, the second abutting surface and the fourth abutting surface are both provided with a buffer layer, and the material hardness of the buffer layer is less than the hardness of the optical lens. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 The overall architecture diagram of the nucleic acid sequencing system provided in the embodiment of the present application;

[0018] Figure 2 A schematic diagram of the structure of an optical detection system provided in an embodiment of the present application;

[0019] Figure 3 A schematic diagram of the installation of optical lenses in a nucleic acid sequencing system provided in an embodiment of the present application;

[0020] Figure 4 This is a schematic diagram of using an optical lens centering device to center and install an optical lens in an embodiment of the present application;

[0021] Figure 5 This is an overall schematic diagram of an optical lens centering device in an embodiment of the present application;

[0022] Figure 6This is a schematic diagram of using an optical lens centering device to center an optical lens in an embodiment of the present application. DETAILED DESCRIPTION

[0023] In order to make the objectives, technical solutions and advantages of the present application clearer, the present application will be further described in detail below in conjunction with the accompanying drawings.

[0024] It should be noted that, unless otherwise defined, the technical terms or scientific terms used in one or more embodiments of this specification should be understood by people with ordinary skills in the field to which this disclosure belongs. The "first", "second" and similar words used in one or more embodiments of this specification do not indicate any order, quantity or importance, but are only used to distinguish different components. "Include" or "comprise" and similar words mean that the elements or objects appearing before the word cover the elements or objects listed after the word and their equivalents, without excluding other elements or objects. "Connect" or "connected" and similar words are not limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. "Up", "down", "left", "right" and the like are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0025] To facilitate understanding of the optical lens centering device provided in the embodiment of the present application, its application scenario is first explained. The optical lens centering device provided in the embodiment of the present application can be used to assist in the installation of optical lenses required in a nucleic acid sequencing system. The functions of the optical lenses in the nucleic acid sequencing system include supporting high-throughput fluorescence microscopy imaging technology, which is used to analyze base sequences in DNA or RNA fragments. The selective light transmission function of the optical lens can enable light of a specific wavelength to pass through the optical lens, so that the nucleic acid sequencing system can effectively capture and analyze the base sequence of DNA or RNA during the imaging process. Therefore, the accurate installation of the optical lenses in the nucleic acid sequencing system plays an important role in the accuracy of the sequencing results.

[0026] See also Figure 1 , Figure 1 The overall architecture diagram of a nucleic acid sequencing system provided by the present disclosure embodiment. Figure 1 As shown, the nucleic acid sequencing system 100 provided in the embodiment of the present disclosure includes: a chip 10, a chip platform 20, a reagent storage container 30, a flow guidance system 40, an optical detection system 50 and a computer system 60.

[0027] Wherein, one or more sequencing objects are attached to the chip 10;

[0028] The chip platform 20 is configured to fix and support the chip 10;

[0029] The reagent storage container 30 is configured to store one or more reagents; here, the reagents may exemplarily include polymerase chain reaction (PCR) fluorescent reagents.

[0030] The flow guiding system 40 is configured to controllably transport the one or more reagents from the reagent storage container 30 to the chip 10 so as to contact with the sequencing object and undergo a chemical reaction;

[0031] The optical detection system 50 is configured to excite the fluorescent marker in the reagent for sequencing and detect the fluorescent signal generated by the excitation of the fluorescent marker;

[0032] The computer system 60 is configured to acquire the fluorescent image from the optical detection system 50 and identify the nucleic acid sequence of the sequencing object according to the fluorescent image.

[0033] See also Figure 2 As shown, Figure 2 This is a schematic diagram of the structure of an optical detection system provided in an embodiment of the present disclosure. The optical detection system 50 at least includes a light source component 501 and an imaging component 502 .

[0034] The imaging assembly 502 at least includes an aperture plate 5021, a dichroic mirror 5022-1, a microscope 5023 and an image sensor 5024. The aperture plate 5021 is provided with a plurality of light holes 5025. The image sensor 5024 may be an industrial camera.

[0035] The light source component 501 emits scattered excitation light, and the excitation light passes through at least some of the multiple light holes on the aperture plate 5021 to form multiple laser light beams and irradiate the dichroic mirror 5022-1; the dichroic mirror 5022-1 reflects the excitation light beams passing through the light holes to the chip 10 to assist the microscope 5023 in focusing; the microscope 5023 collects the fluorescence signals generated by the sequencing objects on the chip 10 after a chemical reaction; the image sensor 5024 senses the fluorescence signals and generates a fluorescence image.

[0036] Optionally, the dichroic mirror 5022-1 can be fixed at a certain angle, and can be fixed by glue dispensing.

[0037] In a possible implementation, the light source component 501 may be a semiconductor laser (Laser Diode, LD). The aperture piece 5021 may be made of an opaque material, exemplarily a metal sheet, and the scattered excitation light emitted by the light source component 501 may only pass through the light-through hole portion, while the non-light-through hole portion of the aperture piece 5021 will block the excitation light.

[0038] In a possible implementation manner, the imaging assembly 502 further includes an attenuation plate 5026, which is disposed in parallel with the aperture plate 5021 and configured to attenuate the intensity of the excitation light beam. Figure 2 As shown, the attenuation plate 5026 can be arranged behind the aperture plate 5021 , and the excitation light beam can directly irradiate the attenuation plate 5026 after passing through the light hole.

[0039] In a possible implementation, the imaging component 502 further includes a convex lens 5027, which is disposed parallel to the attenuation plate 5026 and located between the attenuation plate 5026 and the dichroic mirror 5022-1, and is configured to collimate the excitation light beam into a parallel light beam.

[0040] The microscope 5023 may include an objective lens 50231 and a tube lens 50232 , wherein the objective lens 50231 is located below the dichroic mirror 5022 - 1 , the tube lens 50232 is located above the dichroic mirror 5022 - 1 , and the image sensor 5024 is located above the tube lens 50232 .

[0041] Optionally, a motor is configured on one side of the objective lens 50231, for example, it can be a voice coil motor. Through the motor on the objective lens 50231, the objective lens 50231 can be controlled to move up and down to achieve focusing.

[0042] The optical lens in the embodiment of the present application may be the above Figure 2 The dichroic mirror is an example, but it should be understood that the optical lens provided in the embodiment of the present application is not limited to the dichroic mirror of the above example, and other optical lenses in the nucleic acid sequencing system can also adopt the optical lens centering device provided in the embodiment of the present application.

[0043] refer to Figure 3 , Figure 3The schematic diagram of the installation of the optical lens in the nucleic acid sequencing system includes a base 100 and a lens holder 200, wherein the lens holder 200 is fixedly connected to the base 100 and is used to place the optical lens 300; wherein the lens holder 200 has a V-shaped notch, and a side wall of the V-shaped notch is used to support the optical lens 300. During the installation of the optical lens, the optical lens 300 needs to be placed at a preset position of a side wall of the V-shaped notch of the lens holder 200, and then the optical lens 300 is fixed to the side wall of the V-shaped notch of the lens holder 200 by glue dispensing to complete the installation of the optical lens.

[0044] In the above process, whether the optical lens 300 can be quickly, accurately and continuously fixed at the preset position on the lens holder 200 becomes one of the important factors affecting the installation accuracy and efficiency of the optical lens. In actual applications, since the operator needs to spend a lot of time and energy to accurately place the optical lens 300 at the preset position on the lens holder 200, the installation accuracy and efficiency of the optical lens need to be improved.

[0045] To this end, the present application provides an optical lens centering device, which is used to quickly, accurately and continuously fix the optical lens 300 at a preset position on the lens holder 200 during the installation process of the optical lens, so as to improve the installation accuracy and installation efficiency of the optical lens in the nucleic acid sequencing system. The structural features and application scenarios of the optical lens centering device are described in detail below in conjunction with the accompanying drawings.

[0046] refer to Figure 4 and Figure 5 , Figure 4 The overall schematic diagram of the optical lens centering device 400 in the embodiment of the present application. The optical lens centering device 400 provided in the embodiment of the present application includes a first clamping arm 410 and a second clamping arm 420 arranged opposite to each other, and an elastic connector 430 connecting the first clamping arm 410 and the second clamping arm 420. Thus, a clamping tool is formed. By the elastic force of the elastic connector 430, the first clamping arm 410 and the second clamping arm 420 are clamped on the lens seat 200 and the optical lens 300 at the same time, so that the optical lens 300 is relatively fixed to the lens seat 200, and the optical lens 300 is positioned. It should be understood that the first clamping arm 410 and the second clamping arm 420 are two opposite clamping arms arranged in a mirror image. Thus, when the first clamping arm 410 and the second clamping arm 420 are synchronously clamping the lens seat 200 and the optical lens 300, the lens seat 200 and the optical lens 300 can be centered.

[0047] During the specific abutment, the first clamping arm 410 has a first abutment surface 411 and a second abutment surface 412; the second clamping arm 420 has a third abutment surface 421 and a fourth abutment surface 422; wherein, the first abutment surface 411 and the third abutment surface 421 are arranged relative to each other, and are used to abut one-to-one at the opposite ends of the lens seat 200; the second abutment surface 412 and the fourth abutment surface 422 are arranged relative to each other, and are used to abut one-to-one at the opposite ends of the optical lens 300, thereby realizing the positioning of the optical lens.

[0048] In the embodiment of the present application, by providing an optical lens centering device 400 including a first clamping arm 410 and a second clamping arm 420 arranged at intervals, and an elastic connector 430 connecting the first clamping arm 410 and the second clamping arm 420 for the lens seat 200, the optical lens 300 can be fixed in the lens seat 200 of the nucleic acid sequencing system, so as to facilitate the operator to quickly and accurately place and install the optical lens. Among them, the first abutting surface 411 and the third abutting surface 421 can abut the optical lens centering device 400 on the lens seat 200, and the second abutting surface 412 and the fourth abutting surface 422 can fix the optical lens 300, so that the optical lens 300 can be fixed at a preset position of the lens seat 200, so as to facilitate the operator to accurately and efficiently complete the installation of the optical lens.

[0049] Specifically, the schematic diagram of the optical lens centering device 400 during the installation process can be Figure 5 As shown, Figure 5In the embodiment, the first abutting surface 411 and the third abutting surface 421 of the optical lens centering device 400 are used to abut against the front and rear ends of the same side wall in the V-shaped notch of the lens seat 200 in a one-to-one manner, so as to stably abut the optical lens centering device 400 against the corresponding side wall of the lens seat 200; during the installation process of the optical lens 300, the optical lens centering device 400 can be placed on the lens seat 200 first, and then the optical lens 300 can be placed on the lens seat 200 along the gap between the first clamping arm 410 and the second clamping arm 420. Due to the clamping effect of the optical lens centering device 400, the optical lens 300 can be fixed on the lens seat 200 at this time; alternatively, the optical lens 300 can be placed on the lens seat 200 first. 00, and then place the optical lens centering device 400 on the lens seat 200. Since the optical lens 300 has been placed on the lens seat 200 in advance, the first abutting surface 411 and the third abutting surface 421 can correspond one by one to the front and rear ends of the same side wall in the V-shaped notch of the lens seat 200, so as to stably abut the optical lens centering device 400 on the corresponding side wall of the lens seat 200, and the second abutting surface 412 and the fourth abutting surface 422 can correspond one by one to the opposite ends of the optical lens 300 to achieve the clamping of the optical lens 300, that is, at this time, the clamping effect of the optical lens centering device 400 can be used to fix the optical lens 300 at the preset position of the lens seat 200.

[0050] As an optional embodiment, the elastic connector 430 may be a leaf spring; the two ends of the leaf spring are respectively fixedly connected to the first clamping arm 410 and the second clamping arm 420 through threaded connectors; accordingly, the two ends of the leaf spring have bending structures, each of which is provided with a through hole that matches the corresponding threaded connector, so that the first clamping arm 410 and the second clamping arm 420 can be fixedly connected to the leaf spring through the threaded connectors.

[0051] Specifically, in the process of fixing the first clamping arm 410 and the second clamping arm 420 together through a threaded connector, the first clamping arm 410 and the second clamping arm 420 can be fixedly connected to both ends of the leaf spring through the cooperation of the threaded connector (screws, bolts, etc.) and the through hole.

[0052] In addition, the elastic connector 430 can also be a rubber spring, a memory alloy spring, etc., and the first clamping arm 410 and the second clamping arm 420 can be clamped on the lens holder 200 and the optical lens 300 at the same time through the elastic force of the elastic connector, so as to achieve the positioning of the optical lens 300. The present application does not limit the specific type of the elastic connector.

[0053] As an optional implementation, refer to Figure 4A first recessed structure 413 is provided on the second abutting surface 412 to form a glue dispensing space between the first clamping arm and the optical lens 300, and a second recessed structure 423 is provided on the fourth abutting surface 422 to form a glue dispensing space between the first clamping arm and the optical lens 300.

[0054] Specifically, during the installation of the optical lens, the first recessed structure 413 and the second recessed structure 423 provided on the first clamping arm 410 and the second clamping arm 420 can form an escape space so that a dispensing tool can be inserted into the dispensing space for dispensing, thereby bonding the optical lens 300 to the lens seat 200.

[0055] For reference Figure 4 And reference Figure 6 , Figure 6 This is a schematic diagram of using the optical lens centering device 400 to fix the optical lens 300 in the embodiment of the present application. When the first clamping arm 410 and the second clamping arm 420 fix the optical lens 300 at the preset position of the lens holder 200, the ends of the first clamping arm 410 and the second clamping arm 420 are separated from the ends of the optical lens 300 by a distance, and glue can be dispensed in this part. In addition, glue can also be dispensed in the glue dispensing space formed between the first recessed structure 413 and the second recessed structure 423 and the optical lens 300, thereby improving the stability between the optical lens 300 and the lens holder 200.

[0056] As an optional implementation, the material hardness of the first clamping arm 410 and the second clamping arm 420 is less than the hardness of the optical lens 300 .

[0057] Specifically, the material hardness of the first clamping arm 410 and the second clamping arm 420 can be changed so that the material hardness of the first clamping arm 410 and the second clamping arm 420 is smaller than the hardness of the optical lens 300, so that the optical lens 300 will not be damaged during the process of fixing the optical lens 300 using the first clamping arm 410 and the second clamping arm 420. The material of the first clamping arm 410 and the second clamping arm 420 can be rubber, plastic, etc.

[0058] As an optional implementation, both the second abutting surface 412 and the fourth abutting surface 422 are provided with at least one protrusion.

[0059] Specifically, the protrusions can be distributed in a dotted manner on the second abutting surface 412 and the fourth abutting surface 422 to make the friction force distribution more uniform and avoid damage to the optical lens 300 during the clamping process; the second abutting surface 412 is the abutting surface when the first clamping arm 410 abuts against the optical lens 300, so providing a protrusion on the second abutting surface 412 can increase the static friction force when the first clamping arm 410 abuts against the optical lens 300; the fourth abutting surface 422 is the abutting surface when the second clamping arm 420 abuts against the optical lens 300. The abutment surface of the optical lens 300 when it abuts, therefore, setting a protrusion on the fourth abutment surface 422 can increase the static friction force when the second clamping arm 420 abuts against the optical lens 300, then at least one protrusion is provided on the second abutment surface 412 and the fourth abutment surface 422, which can increase the static friction force when the optical lens 300 is fixed at a preset position from both sides of the optical lens clamping direction, thereby avoiding the problem of large installation deviation of the optical lens 300 due to the displacement of the optical lens during the subsequent assembly process.

[0060] As an optional implementation, refer to Figure 4 The optical lens centering device 400 also includes a handle; the handle includes a first handle and a second handle, the first handle is fixed to the first clamping arm 410; the second handle is fixed to the second clamping arm 420.

[0061] In practical applications, since an optical lens centering device often needs to be repeatedly used in the installation process of different optical lenses, the optical lens centering device needs to be taken. In order to facilitate the taking of the optical lens centering device, handles can be respectively provided on the first clamping arm 410 and the second clamping arm 420 of the optical lens centering device, so that the optical lens centering device can be conveniently and stably taken by the handles on the first clamping arm 410 and the second clamping arm 420.

[0062] Specifically, the first handle can be fixed to the first clamping arm 410 through a plurality of matching threaded through holes (i.e., the first through hole 414) and a threaded connector, and the second handle can be fixed to the second clamping arm 420 through a plurality of matching threaded through holes (i.e., the second through hole 424) and a threaded connector. The threaded through holes on the first clamping arm 410 and the second clamping arm 420 can be as shown in FIG. Figure 4 As shown, Figure 4 The first clamping arm 410 and the second clamping arm 420 include two threaded through holes, one of which is located at the corresponding position of the protrusion. Through the cooperation of multiple dispersed threaded through holes and threaded connectors, the handle can be stably fixed on the clamping arm of the optical lens centering device, so that the optical lens centering device 400 can be conveniently and stably taken by the handle.

[0063] As an optional implementation, refer to Figure 4 , Figure 5 and Figure 6 The first clamping arm 410 and the second clamping arm 420 both have a first arm abutting against one side wall of the V-shaped notch, and a second arm abutting against the other side wall of the V-shaped notch; the first arm is fixedly connected to the second arm; the first abutting surface 411 and the second abutting surface 412 of the first clamping arm 410 are located on the second arm of the first clamping arm 410; the third abutting surface 421 and the fourth abutting surface 422 of the second clamping arm 420 are located on the second arm of the second clamping arm 420.

[0064] Specifically, the V-shaped structure formed by the first clamping arm 410 and the second clamping arm 420 through the first arm and the second arm can enable the optical lens centering device 400 to fit in the V-shaped notch on the lens seat 200 and stably abut on the lens seat 200 through the corresponding abutment surface, thereby facilitating the subsequent placement and installation of the optical lens.

[0065] As an optional implementation, refer to Figure 4 The first clamping arm 410 has a fifth abutting surface 415 for abutting against the lens seat 200, and the fifth abutting surface 415 is connected to the first abutting surface 411 to form an L-shaped surface; the second clamping arm 420 has a sixth abutting surface 425 for abutting against the lens seat 200, and the sixth abutting surface 425 is connected to the third abutting surface 421 to form an L-shaped surface.

[0066] Specifically, the fifth abutment surface 415 is connected to the first abutment surface 411 and forms an L-shaped surface, which can form a step structure of the first clamping arm 410 on the side close to the lens seat 200, so that the first clamping arm 410 can be stably abutted against the lens seat 200; the sixth abutment surface 425 is connected to the third abutment surface 421 and forms an L-shaped surface, which can form a step structure of the second clamping arm 420 on the side close to the lens seat 200, so that the second clamping arm 420 can be stably abutted against the lens seat 200.

[0067] As an optional implementation, the second abutting surface 412 and the fourth abutting surface 422 are both provided with a buffer layer, and the hardness of the material of the buffer layer is less than the hardness of the optical lens 300 .

[0068] Specifically, since the hardness of the optical lens 300 is relatively low, during the process of installing the optical lens, if the hardness of the contact position corresponding to the second abutting surface 412 and the fourth abutting surface 422 is relatively high, it may cause damage to the optical lens 300 when fixing the optical lens. Therefore, a buffer layer may be provided on the second abutting surface 412 and the fourth abutting surface 422 to avoid damage to the optical lens 300 when fixing the optical lens 300. The material of the buffer layer may be rubber, plastic, etc.

[0069] The embodiment of the present application also provides a nucleic acid sequencing system, comprising a base 100, a lens seat 200, an optical lens 300 and an optical lens centering device 400 as described in any one of the above items; wherein the first abutting surface 411 and the third abutting surface 421 of the optical lens centering device 400 abut against the opposite ends of the lens seat 200 in a one-to-one manner; the second abutting surface 412 and the fourth abutting surface 422 abut against the opposite ends of the optical lens 300 in a one-to-one manner.

[0070] Specifically, the connection method of each component in the nucleic acid sequencing system can refer to Figure 5 and Figure 6 The relevant description in will not be repeated here.

[0071] In this way, since the first abutting surface 411 and the third abutting surface 421 of the optical lens centering device 400 abut against the opposite ends of the lens seat 200 in a one-to-one manner; the second abutting surface 412 and the fourth abutting surface 422 abut against the opposite ends of the optical lens 300 in a one-to-one manner, the optical lens 300 can be quickly, accurately and continuously fixed at the preset position on the lens seat 200, so as to improve the installation accuracy and efficiency of the optical lens in the nucleic acid sequencing system.

[0072] One or more embodiments of this specification are intended to cover all such substitutions, modifications and variations that fall within the broad scope of the appended claims. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of one or more embodiments of this specification should be included in the scope of protection of this disclosure.

[0073] The above are only specific implementations of the present application, but the protection scope of the present application is not limited thereto. Any technician familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present application, which should be included in the protection scope of the present application. Therefore, the protection scope of the present application should be based on the protection scope of the claims.

Claims

1. An optical lens centering device, used to install an optical lens in a nucleic acid sequencing system on a lens seat, characterized in that: The optical lens centering device comprises: a first clamping arm and a second clamping arm which are arranged opposite to each other, and an elastic connecting member which connects the first clamping arm and the second clamping arm; The first clamping arm has a first abutting surface and a second abutting surface; the second clamping arm has a third abutting surface and a fourth abutting surface; wherein the first abutting surface and the third abutting surface are arranged opposite to each other and are used to abut against the opposite ends of the lens seat in a one-to-one correspondence; the second abutting surface and the fourth abutting surface are arranged opposite to each other and are used to abut against the opposite ends of the optical lens in a one-to-one correspondence.

2. The optical lens centering device according to claim 1, characterized in that: The elastic connecting member is a leaf spring; Two ends of the leaf spring are fixedly connected to the first clamping arm and the second clamping arm through threaded connectors respectively.

3. The optical lens centering device according to claim 2, characterized in that: Both ends of the leaf spring have bending structures respectively, and each bending structure is provided with a through hole matched with a corresponding threaded connector.

4. The optical lens centering device according to claim 1, characterized in that: A first concave structure is provided on the second abutting surface to form a glue dispensing space between the first clamping arm and the optical lens; A second recessed structure is disposed on the fourth abutting surface to form a glue dispensing space between the first clamping arm and the optical lens.

5. The optical lens centering device according to claim 4, characterized in that: The material hardness of the first clamping arm and the second clamping arm is smaller than the hardness of the optical lens.

6. The optical lens centering device according to claim 1, characterized in that: The second abutting surface and the fourth abutting surface are each provided with at least one protrusion.

7. The optical lens centering device according to claim 1, characterized in that: The optical lens centering device also includes a handle; the handle includes a first handle and a second handle, the first handle is fixed to the first clamping arm; the second handle is fixed to the second clamping arm.

8. The optical lens centering device according to any one of claims 1 to 7, characterized in that: The lens seat has a V-shaped notch; wherein a side wall of the V-shaped notch is used to support the optical lens; The first clamping arm and the second clamping arm each have a first support arm abutting against one side wall of the V-shaped notch, and a second support arm abutting against the other side wall of the V-shaped notch; the first support arm is fixedly connected to the second support arm; The first abutting surface and the second abutting surface of the first clamping arm are located on the second support arm of the first clamping arm; The third abutting surface and the fourth abutting surface of the second clamping arm are located on the second support arm of the second clamping arm.

9. The optical lens centering device according to any one of claims 1 to 7, characterized in that: The first clamping arm has a fifth abutting surface for abutting against the lens seat, wherein the fifth abutting surface is connected to the first abutting surface and forms an L-shaped surface; The second clamping arm has a sixth abutting surface for abutting against the lens seat, and the sixth abutting surface is connected to the third abutting surface to form an L-shaped surface.

10. The optical lens centering device according to any one of claims 1 to 7, characterized in that: The second abutting surface and the fourth abutting surface are both provided with a buffer layer, and the material hardness of the buffer layer is less than the hardness of the optical lens.

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