Multi-channel protein purification instrument
By setting up mobile components and placing components in a multi-channel protein purification device, the inconvenient pick-up and adaptation of centrifuge tubes of different sizes is solved, and convenient operation procedures and efficient protein purification work are achieved.
Patent Information
- Application Number
- CN202420673608.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-03
- Publication Date
- 2025-03-14
- Estimated Expiration
- 2034-04-03
AI Technical Summary
There are two problems in the use of existing multi-channel protein purifiers: First, the installation position of the test tube rack is low, which is inconvenient for staff to pick up and place the test tube rack; second, the size and model of the test tube rack are fixed, and it cannot adapt to different models of centrifuge tubes, which increases the preparation work of staff.
By setting the moving component and the placement component in the multi-channel protein purification instrument, the moving component drives the placement plate longitudinally through the first screw and the first slider, and drives the lifting plate vertically through the second screw and the second slider, solving the problem of picking and placement of the test tube rack; the placement component drives the movable ply through the third screw and the third slider, changing the spacing between the fixed ply and the movable ply, adapting to centrifugal tubes of different sizes.
It realizes the convenient pick-up and the adaptation of centrifuge tubes of different sizes, which improves work efficiency and reduces the complexity of preparation work.
Smart Images

Figure CN222613222U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of organic chemical engineering, and particularly relates to a multi-channel protein purification instrument. Background Art
[0002] With the development of society, people now have more and more demands for various organic compounds in their daily production and life, which leads to an increasing production of organic compounds, thus promoting the development of organic chemistry. In the production and preparation of various organic compounds, a large number of equipment are used. Among them, protein purifier is a common production equipment of organic chemical engineering. The main function of protein purifier is to separate protein samples with higher purity from complex biological samples.
[0003] The existing document with the publication number CN110790813B discloses a multi-channel protein purifier, including multiple channels, each channel forming an independent liquid path, and each channel sequentially including a solvent / sample selection valve, an infusion pump, a bubble / liquid level sensor, a chromatography column, and a concentration detector according to the flow direction of the liquid path, wherein the multi-channel protein purifier also has a collection module and a control module shared by multiple channels, wherein the control module is connected to and controls the operation of the solvent / sample selection valve, the infusion pump, the bubble / liquid level sensor, and the concentration detector, wherein the solvent / sample selection valve has a solvent inlet and a sample inlet, as well as a solution outlet, wherein the infusion pump is used to input the solution output by the solvent / sample selection valve into the chromatography column, wherein the concentration detector is used to detect the concentration of the target protein in the solution purified by the chromatography column, and wherein the collection module is used to collect the target protein;
[0004] However, it still has the following disadvantages in actual use:
[0005] 1. The multi-channel protein purifier described above has a collection module including two test tube racks, and the test tube racks can hold test tubes of various specifications including 15ml centrifuge tubes, 50ml centrifuge tubes, 1.5ml centrifuge tubes, 96-well collection plates, and 2ml glass sample bottles. The various centrifuge tubes are placed on the racks, but since the overall installation position of the collection module is relatively low, it is inconvenient for the staff to take and place the test tube racks;
[0006] 2. The multi-channel protein purifier mentioned above also has a collection module and a control module shared by multiple channels, and the collection module includes two test tube racks, through which centrifuge tubes are placed. However, since the size and model of the test tube racks are fixed, the same model of test tube racks can only hold the same model of centrifuge tubes. However, in the process of protein purification, a large number of centrifuge tubes of different models may be used, which leads to the need to prepare test tube racks of multiple models, increasing the staff's advance preparation work.
[0007] To this end, we provide a multi-channel protein purification instrument to solve the above problems. Utility Model Content
[0008] The purpose of the utility model is to provide a multi-channel protein purification instrument, which drives the placement plate to move in the longitudinal direction through the installation frame and the first screw rod in the moving component, and drives the lifting plate and the placement plate to move up and down through the second drive motor and the connecting rod, thereby solving the existing problem that it is inconvenient to take and place the test tube rack, and drives the movable clamping plate to move through the third screw rod and the connecting strip in the placement component, and clamps the centrifuge tube through the fixed clamping plate and the movable clamping plate, thereby solving the existing problem that it is inconvenient to fix centrifuge tubes of different sizes.
[0009] In order to solve the above technical problems, the utility model is realized by the following technical solutions:
[0010] The utility model is a multi-channel protein purifier, comprising a purifier body, both sides of the front end of the purifier body are provided with a placement plate through a moving component, and a placement component is also provided on the placement plate;
[0011] The two sets of mounting frames in the moving assembly are respectively fixedly connected to the front sides of the purifier body in the longitudinal direction, and the interior of the mounting frame is rotatably connected to a first screw rod in the longitudinal direction, and a first slider is threadedly sleeved on the outer wall of the first screw rod, and a moving plate is fixedly connected to the top of the first slider, and a lifting plate is movably connected to the top of the moving plate through a connecting rod;
[0012] The fixing plate in the placing assembly is placed on the upper surface of the placing plate, and a lifting frame is movably connected to the top of the fixing plate through a first set of rods, the front and rear ends of the lifting frame are both fixedly connected to fixed clamping plates along the horizontal direction, and the front and rear ends between adjacent fixed clamping plates are movably connected to movable clamping plates, and the center position of the lifting frame is rotatably connected to a third screw rod along the horizontal direction, and third sliding blocks are threadedly sleeved on both sides of the outer wall of the third screw rod, and connecting strips are rotatably connected to the front and rear end surfaces of the third sliding block, and the ends of the connecting strips away from the third sliding block are rotatably connected to the sides of the movable clamping plates close to each other.
[0013] The utility model is further configured as follows: adjacent installation frames are fixedly connected with first drive motors via first motor frames, the output shaft of the first drive motor and the front end of the first screw rod are sleeved with synchronous wheels, and the synchronous wheels are connected via belt transmission.
[0014] The utility model is further configured as follows: a second driving motor is fixedly connected to a side of an upper surface of the movable plate through a second motor frame, a second screw rod is fixedly connected to an output shaft of the second driving motor, a first sliding rod is fixedly connected to a lower surface of the lifting plate in the horizontal direction through a mounting seat, a second sliding rod is movably sleeved on both sides of the outer walls of the second screw rod and the first sliding rod, a mounting rod is fixedly connected to the front and rear end surfaces of the second sliding rod, and both ends of the connecting rod are movably sleeved on an end of the mounting rod away from the second sliding rod.
[0015] The utility model is further configured as follows: a bearing seat is fixedly connected to the other side of the upper surface of the movable plate, and an end of the second screw rod away from the second drive motor is rotatably sleeved on the inner side of the bearing seat.
[0016] The utility model is further configured as follows: a first set of rods are vertically penetrated around the surface of the movable plate, a first inner rod is movably sleeved inside the first set of rods, and the top ends of the first inner rods are respectively welded around the lower surface of the placement plate.
[0017] The utility model is further configured as follows: side plates are welded on both side outer walls of the lifting plate, and one side outer wall of the side plate is respectively abutted and connected to the two side outer walls of the placing plate.
[0018] The utility model is further configured as follows: second sliding rods are welded around the upper surface of the fixed plate, the top ends of the second sliding rods are movably passed through the surface of the lifting frame and are threadedly sleeved with limit nuts, mounting plates are welded on the front end surfaces of the fixed plate and the lifting frame, the bottom ends of the second set of rods are rotatably connected to the upper surface of the mounting plate located on the fixed plate, an anti-slip sleeve is bonded to the outer wall of the second set of rods, the internal threaded sleeve of the second set of rods is provided with a second inner rod, and the end of the second inner rod away from the second set of rods is fixedly connected to the lower surface of the mounting plate located on the lifting frame.
[0019] The utility model is further configured as follows: grooves are provided at the front and rear ends of the inner walls on both sides of the lifting frame in the longitudinal direction; protrusions are movably connected inside the grooves; one side of the protrusions passes through the grooves and is respectively welded to the outer walls on both sides of the movable clamping plate; a plurality of groups of arc grooves are provided on the facing surfaces of the fixed clamping plate and the movable clamping plate at equal intervals in the transverse direction; and rubber pads are bonded to the inner sides of the arc grooves.
[0020] The utility model is further configured as follows: two ends of the third screw rod respectively rotate to penetrate the inner walls of both sides of the lifting frame and are fixedly connected with knobs, and the knobs are respectively located on both sides of the lifting frame.
[0021] The utility model has the following beneficial effects:
[0022] 1. The utility model sets a moving component, and drives the moving plate to move in the longitudinal direction through the threaded connection between the first screw rod and the first slider, and drives the connecting rod to move through the threaded connection between the second screw rod and the second slider, thereby driving the lifting plate to drive the moving plate to move vertically, thereby driving the centrifuge tubes on the placement plate to move, which is convenient for the staff to take and place the centrifuge tubes.
[0023] 2. The utility model sets a placement component, and the threaded connection between the third screw rod and the third slider drives the connecting strip to move, and the connecting strip drives the movable clamping plate to move, thereby changing the spacing between the fixed clamping plate and the movable clamping plate. Centrifuge tubes of different sizes are clamped and fixed by fixed clamping plates and movable clamping plates with different spacings, which facilitates the use of centrifuge tubes of different sizes for protein purification.
[0024] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.
[0026] Figure 1 It is a schematic diagram of the overall structure of a multi-channel protein purification instrument;
[0027] Figure 2 It is a structural schematic diagram of the mobile component of the utility model;
[0028] Figure 3 This is a schematic diagram of the structure of the installation frame of the utility model;
[0029] Figure 4 It is a structural schematic diagram of the movable plate of the utility model;
[0030] Figure 5 This is a structural schematic diagram of the lifting plate of the utility model;
[0031] Figure 6 It is a structural schematic diagram of the placement plate of the utility model;
[0032] Figure 7 It is a structural schematic diagram of the placement components of the utility model;
[0033] Figure 8 It is a schematic diagram of the installation between the movable clamping plate and the third screw rod of the utility model;
[0034] Fig. 9 It is a structural schematic diagram of the second set of rods of the utility model.
[0035] In the accompanying drawings, the components represented by the reference numerals are listed as follows:
[0036] 1-purifier body, 2-moving assembly, 201-installing frame, 202-first screw rod, 203-first slider, 204-moving plate, 204a-first set of rods, 205-connecting rod, 206-lifting plate, 206a-side plate, 207-first drive motor, 207a-first motor frame, 207b-synchronous wheel, 207c-belt, 208-second screw rod, 208a-second drive motor, 208b-second motor frame, 208c-bearing seat, 208d-second slider, 208e-installing rod, 209-first slider Rod, 209a-mounting seat, 3-placing plate, 301-first inner rod, 4-placing assembly, 401-fixed plate, 401a-mounting plate, 401b-second slide rod, 401c-limiting nut, 402-lifting frame, 402a-groove, 403-fixed clamping plate, 404-moving clamping plate, 404a-bump, 404b-arc groove, 404c-rubber pad, 405-third screw rod, 405b-knob, 405c-third slider, 406-connecting strip, 407-second set of rods, 407a-anti-slip sleeve, 408-second inner rod. DETAILED DESCRIPTION
[0037] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. Specific embodiment 1
[0039] See also Figure 1-6 As shown, it is the first embodiment of the utility model, which provides a multi-channel protein purifier, including a purifier body 1, a moving component 2 and a placement plate 3, and the moving component 2 includes a mounting frame 201, a first screw rod 202, a moving plate 204, a connecting rod 205 and a lifting plate 206. The placement plate 3 is driven to move longitudinally by the first screw rod 202 and the moving plate 204, and the placement plate 3 is driven to move vertically by the connecting rod 205 and the lifting plate 206, thereby solving the problem of the inconvenience of taking and placing the test tube rack.
[0040] Specifically, the mounting frames 201 are respectively fixedly connected to the front ends of the purifier body 1 along the longitudinal direction, and the interior of the mounting frame 201 is rotatably connected to the first screw rod 202 along the longitudinal direction. The outer wall of the first screw rod 202 is threadedly sleeved with a first slider 203, and the top of the first slider 203 is fixedly connected to a movable plate 204, and the upper part of the movable plate 204 is movably connected to a lifting plate 206 through a connecting rod 205, and the connecting rods 205 are rotatably connected to each other. The mounting frame 201 is set to install the first screw rod 202, and the threaded connection between the first screw rod 202 and the first slider 203 drives the movable plate 204 to move in the longitudinal direction, and the setting of the connecting rod 205 drives the lifting plate 206 to move vertically relative to the movable plate 204, thereby driving the placement plate 3 to move vertically.
[0041] Further, the first drive motor 207 is fixedly connected between adjacent mounting frames 201 through a first motor frame 207a, and the output shaft of the first drive motor 207 and the front end of the first screw rod 202 are both sleeved with a synchronous wheel 207b, and the synchronous wheels 207b are connected by a belt 207c. The first motor frame 207a is used to fix the first drive motor 207, and the first drive motor 207 is used to drive the synchronous wheel 207b to rotate, and the first screw rod 202 is driven to rotate through the transmission connection between the synchronous wheel 207b and the belt 207c;
[0042] A second drive motor 208a is fixedly connected to one side of the upper surface of the movable plate 204 through a second motor frame 208b, and a second screw rod 208 is fixedly connected to the output shaft of the second drive motor 208a. A first slide bar 209 is fixedly connected to the lower surface of the lifting plate 206 through a mounting seat 209a in the horizontal direction. Second slide bars 208d are movably sleeved on both sides of the outer walls of the second screw rod 208 and the first slide bar 209. The second screw rod 208 and the second slide bar 208d are connected by screw thread engagement, and the first slide bar 209 and the second slide bar 208d are connected by a sliding sleeve. The front and rear end surfaces of the second slide bar 208d are fixedly connected with mounting rods 208e, and the connecting rod 205 Both ends are movably sleeved on the end of the mounting rod 208e away from the second slider 208d, the second motor frame 208b is used to install the second drive motor 208a, and the second drive motor 208a is used to drive the second screw rod 208 to rotate, and at the same time, under the action of the threaded connection between the second screw rod 208 and the second slider 208d, the second screw rod 208 drives the lower end of the connecting rod 205 to move relative or back to back through the second slider 208d, and the mounting seat 209a is used to install the first slide bar 209 on the lifting plate 206, and at the same time, the upper end of the connecting rod 205 is movably installed on the lifting plate 206 through the first slide bar 209 and the second slider 208d;
[0043] A bearing seat 208c is fixedly connected to the other side of the upper surface of the movable plate 204, and one end of the second screw rod 208 away from the second drive motor 208a is rotatably sleeved on the inner side of the bearing seat 208c, and the bearing seat 208c is used to rotatably install the end of the second screw rod 208 away from the second drive motor 208a;
[0044] The surface of the movable plate 204 is vertically penetrated by a first set of rods 204a, and the first set of rods 204a are movably sleeved with a first inner rod 301. The top ends of the first inner rods 301 are respectively welded to the lower surface of the placement plate 3. The first set of rods 204a and the first inner rods 301 are used to movably connect the movable plate 204 and the placement plate 3.
[0045] Side plates 206 a are welded to both side outer walls of the lifting plate 206 , and one side outer wall of the side plate 206 a is respectively abutted and connected to both side outer walls of the placement plate 3 . The side plate 206 a is used to fix the placement plate 3 on the lifting plate 206 .
[0046] The operation process of this embodiment is as follows: the first drive motor 207 is started, and the output shaft of the first drive motor 207 drives the synchronous wheel 207b to rotate synchronously, and under the transmission action of the belt 207c, the synchronous wheel 207b drives the first screw rod 202 to rotate synchronously, and under the action of the threaded connection between the first screw rod 202 and the first slider 203, the first slider 203 drives the moving plate 204 to move longitudinally, so that the test tube rack on the placement plate 3 moves to the front end of the protein purifier body 1, and then the second drive motor 208a is started, and the output shaft of the second drive motor 208a drives the second screw rod 208 to rotate synchronously, and under the action of the threaded connection between the second screw rod 208 and the second slider 208d, the second slider 208d drives the lower end of the connecting rod 205 to move toward each other, so that the upper end of the connecting rod 205 applies an external force to the lifting plate 206, and then the lifting plate 206 drives the placement plate 3 to move vertically, which is convenient for the staff to take and place the test tube rack detected in the protein purifier body 1. Specific embodiment 2
[0048] See also Figure 7-9As shown, it is the second embodiment of the utility model, which is based on the previous embodiment, but is different from the previous embodiment in that: a placement component 4 is also arranged on the placement plate 3, and the placement component 4 includes a fixed plate 401, a lifting frame 402, a fixed clamping plate 403, a movable clamping plate 404 and a third screw rod 405. The movable clamping plate 404 is driven to move by the third screw rod 405, and centrifuge tubes of different sizes are fixed by the movable clamping plate 404 and the fixed clamping plate 403, which solves the existing problem of inconvenience in fixing centrifuge tubes of different sizes.
[0049] Specifically, the fixed plate 401 is placed on the upper surface of the placement plate 3, and the upper part of the fixed plate 401 is movably connected to the lifting frame 402 through the first set of rods 204a. The front and rear ends of the lifting frame 402 are both fixedly connected to the fixed clamping plate 403 in the horizontal direction, and the front and rear ends of the adjacent fixed clamping plates 403 are both movably connected to the movable clamping plate 404. The center position of the lifting frame 402 is rotatably connected to the third screw rod 405 in the horizontal direction, and the third slider 405c is threadedly sleeved on both sides of the outer wall of the third screw rod 405. The front and rear end surfaces of the third slider 405c are rotatably connected to the connecting strip 406, and the connecting strip 406 is away from the third slider 405. One end of c is rotatably connected to the side of the movable clamping plate 404 that is close to each other, the setting of the fixed plate 401 is used to install the lifting frame 402 and other structures, and the centrifuge tubes of different lengths are placed through the movable connection between the fixed plate 401 and the lifting frame 402, the setting of the movable clamping plate 404 and the fixed clamping plate 403 is used to clamp and fix the centrifuge tube, and the setting of the third screw rod 405 and the third slider 405c is used to drive the movable clamping plate 404 to move relative to the fixed clamping plate 403, and the setting of the connecting strip 406 is used to make a movable connection between the third slider 405c and the movable clamping plate 404.
[0050] Furthermore, second slide bars 401b are welded around the upper surface of the fixed plate 401, and the top ends of the second slide bars 401b are respectively movably penetrated through the surface of the lifting frame 402 and threadedly sleeved with limit nuts 401c. Mounting plates 401a are welded on the front end surfaces of the fixed plate 401 and the lifting frame 402, and the bottom ends of the second rods 407 are rotatably connected to the upper surface of the mounting plate 401a located on the fixed plate 401, and an anti-slip sleeve 407a is bonded to the outer wall of the second rod 407, and the inner thread sleeve of the second rod 407 is provided with a second inner rod 408, one end of the second inner rod 408 away from the second sleeve rod 407 is fixedly connected to the lower surface of the mounting plate 401a located on the lifting frame 402, the second slide rod 401b and the limit nut 401c are used to flexibly connect the fixed plate 401 and the lifting frame 402, and the lifting frame 402 is driven to move relative to the fixed plate 401 through the second sleeve rod 407 and the second inner rod 408, and the anti-slip sleeve 407a is convenient for applying external force to the second sleeve rod 407, so as to facilitate the rotation of the second sleeve rod 407;
[0051] The front and rear ends of the inner walls on both sides of the lifting frame 402 are longitudinally provided with grooves 402a, and the interiors of the grooves 402a are movably connected with protrusions 404a, one side of the protrusions 404a penetrates the grooves 402a and is respectively welded to the outer walls on both sides of the movable clamping plate 404, and the facing surfaces of the fixed clamping plate 403 and the movable clamping plate 404 are horizontally provided with multiple groups of arc grooves 404b at equal intervals, and the inner sides of the arc grooves 404b are bonded with rubber pads 404c, and the arrangement of the grooves 402a and the protrusions 404a is used to movably install the movable clamping plate 404 on the inner side of the lifting frame 402, and the arrangement of the arc grooves 404b and the rubber pads 404c is convenient for clamping the centrifuge tube;
[0052] Both ends of the third screw rod 405 are rotated to penetrate the inner walls of the lifting frame 402 on both sides and are fixedly connected with knobs 405b. The knobs 405b are respectively located on both sides of the lifting frame 402. The setting of the knobs 405b facilitates the rotation of the third screw rod 405.
[0053] The rest of the structure is the same as that of the first embodiment.
[0054] The operation process of this embodiment is: first, an external force is applied to the second set rod 407, so that under the action of the threaded connection between the second set rod 407 and the second inner rod 408, the second inner rod 408 applies an external force to the lifting frame 402, thereby facilitating the fixation of centrifuge tubes of different lengths, and then the knob 405b is rotated, and the knob 405b drives the third screw rod 405 to rotate synchronously, and under the action of the threaded connection between the third screw rod 405 and the third slider 405c, the third slider 405c drives the moving clamp 404 to move through the connecting strip 406, thereby facilitating the fixation of centrifuge tubes of different sizes.
[0055] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.
[0056] The preferred embodiments of the utility model disclosed above are only used to help explain the utility model. The preferred embodiments do not describe all the details in detail, nor do they limit the utility model to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the utility model, so that technicians in the relevant technical field can well understand and use the utility model. The utility model is limited only by the claims and their full scope and equivalents.
Claims
1. A multi-channel protein purifier, comprising a purifier body (1), characterized in that: Both sides of the front end of the purifier body (1) are provided with a placement plate (3) through a moving assembly (2), and two groups of mounting frames (201) in the moving assembly (2) are respectively fixedly connected to both sides of the front end of the purifier body (1) in the longitudinal direction, a first screw rod (202) is rotatably connected inside the mounting frame (201) in the longitudinal direction, and a first slider (203) is threadedly sleeved on the outer wall of the first screw rod (202), a moving plate (204) is fixedly connected to the top of the first slider (203), and a lifting plate (206) is movably connected to the top of the moving plate (204) through a connecting rod (205); The placement plate (3) is also provided with a placement assembly (4), and a fixed plate (401) in the placement assembly (4) is placed on the upper surface of the placement plate (3), and a lifting frame (402) is movably connected to the upper side of the fixed plate (401) through a first set of rods (204a), and the front and rear ends of the lifting frame (402) are both fixedly connected to fixed clamping plates (403) in a transverse direction, and the front and rear ends of adjacent fixed clamping plates (403) are both movably connected to movable clamping plates (404), and a third screw rod (405) is rotatably connected to the center position of the lifting frame (402) in a transverse direction, and third sliders (405c) are threadedly sleeved on both sides of the outer wall of the third screw rod (405), and connecting strips (406) are rotatably connected to the front and rear end surfaces of the third slider (405c), and the ends of the connecting strips (406) away from the third slider (405c) are respectively rotatably connected to the sides of the movable clamping plates (404) that are close to each other.
2. A multi-channel protein purification instrument according to claim 1, characterized in that: The first drive motors (207) are fixedly connected between adjacent mounting frames (201) via first motor frames (207a), and the output shaft of the first drive motor (207) and the front end of the first screw rod (202) are both sleeved with synchronous wheels (207b), and the synchronous wheels (207b) are connected by belts (207c).
3. A multi-channel protein purification instrument according to claim 1, characterized in that: One side of the upper surface of the movable plate (204) is fixedly connected to a second drive motor (208a) via a second motor frame (208b), and a second screw rod (208) is fixedly connected to the output shaft of the second drive motor (208a), and the lower surface of the lifting plate (206) is fixedly connected to a first slide bar (209) in the transverse direction via a mounting seat (209a), and second slide bars (208d) are movably sleeved on both sides of the outer walls of the second screw rod (208) and the first slide bar (209), and mounting rods (208e) are fixedly connected to the front and rear end surfaces of the second slide bar (208d), and both ends of the connecting rod (205) are movably sleeved on one end of the mounting rod (208e) away from the second slide bar (208d).
4. A multi-channel protein purification instrument according to claim 3, characterized in that: A bearing seat (208c) is fixedly connected to the other side of the upper surface of the movable plate (204), and one end of the second screw rod (208) away from the second drive motor (208a) is rotatably sleeved on the inner side of the bearing seat (208c).
5. A multi-channel protein purification instrument according to claim 1, characterized in that: The surface of the movable plate (204) is vertically penetrated by a first set of rods (204a), and the first set of rods (204a) is movably sleeved with a first inner rod (301), and the top end of the first inner rod (301) is respectively welded to the lower surface of the placement plate (3) around the periphery.
6. A multi-channel protein purification instrument according to claim 1, characterized in that: Side plates (206a) are welded to both side outer walls of the lifting plate (206), and one side outer wall of the side plate (206a) is respectively abutted and connected to both side outer walls of the placement plate (3).
7. A multi-channel protein purification instrument according to claim 1, characterized in that: Second sliding rods (401b) are welded around the upper surface of the fixed plate (401), and the top ends of the second sliding rods (401b) are movably passed through the surface of the lifting frame (402) and are threadedly sleeved with limiting nuts (401c), and mounting plates (401a) are welded on the front end surfaces of the fixed plate (401) and the lifting frame (402), the bottom end of the second rod (407) is rotatably connected to the upper surface of the mounting plate (401a) located on the fixed plate (401), and an anti-slip sleeve (407a) is bonded to the outer wall of the second rod (407), the inner thread sleeve of the second rod (407) is provided with a second inner rod (408), and the end of the second inner rod (408) away from the second rod (407) is fixedly connected to the lower surface of the mounting plate (401a) located on the lifting frame (402).
8. A multi-channel protein purification instrument according to claim 1, characterized in that: The front and rear ends of the inner walls on both sides of the lifting frame (402) are provided with grooves (402a) in the longitudinal direction, and the inside of the grooves (402a) is movably connected with protrusions (404a), one side of the protrusions (404a) passes through the grooves (402a) and is respectively welded to the outer walls on both sides of the movable clamping plate (404), and the facing surfaces of the fixed clamping plate (403) and the movable clamping plate (404) are provided with multiple groups of arc grooves (404b) at equal intervals in the horizontal direction, and the inner sides of the arc grooves (404b) are bonded with rubber pads (404c).
9. A multi-channel protein purification instrument according to claim 1, characterized in that: The two ends of the third screw rod (405) are respectively rotated to penetrate the inner walls on both sides of the lifting frame (402) and are fixedly connected with knobs (405b), and the knobs (405b) are respectively located on both sides of the lifting frame (402).
Citation Information
Patent Citations
Multichannel protein purification instrument
CN110790813B
Cited By
Multi-channel protein purification instrument
CN224166951U