Centrifugal automatic balancing device of perforated plate

Abstract

The utility model provides a centrifugal automatic balancing device of a perforated plate, which comprises a variable counterweight box, a counterweight platform assembly and a counterweight adjusting assembly, the counterweight platform assembly is used for placing a perforated plate reagent rack to be balanced before centrifugal operation and the variable counterweight box, and weighing the perforated plate reagent rack and the variable counterweight box in sequence; the variable counterweight box is provided with a hollow cavity and used for containing a liquid counterweight matrix, the counterweight adjusting assembly increases and decreases the liquid counterweight matrix into the variable counterweight box according to weighing data, the weight of the liquid counterweight matrix is kept consistent with the weight of the perforated plate reagent shelf, the counterweight process is automatically achieved, and the perforated plate reagent shelf to be trimmed is placed and weighed through the counterweight platform assembly. The weight of the variable counterweight box is correspondingly increased or decreased according to the numerical value, a liquid counterweight matrix is adopted as an actual carrier for increasing or decreasing the counterweight, a cavity is formed in the variable counterweight box to contain the liquid counterweight matrix, and the weight of the counterweight box is made to be equal to the weight of the perforated plate reagent shelf to complete balancing.

Description

Technical Field

[0001] The utility model relates to the technical field of medical detection equipment, in particular to a centrifugal automatic balancing device for a porous plate. Background Art

[0002] In the medical testing instruments of the in vitro diagnostic industry, some solutions need to be centrifuged. Generally, a multi-well plate reagent rack is used to store sample tubes containing solutions. The 96-well plate reagent rack is a commonly used multi-well plate rack. The pre-process of the centrifugation process needs to be carried out with a counterweight block to ensure that the total weight distribution of the multi-well plate and the reagents thereon meets the process requirements of the centrifugation operation. Before centrifugation, the counterweight block is pre-balanced to make the weight of the counterweight block and the multi-well plate body to be centrifuged as close as possible.

[0003] The step of balancing the weight of the counterweight is generally performed manually, and the operator adds or removes the counterweight on the centrifuge device according to the actual weight of the reagent tubes stored on the porous plate. When the counterweight of the porous plate is balanced in this way, the counterweight needs to be readjusted every time the reagent tubes are added or removed, which greatly increases the time of the centrifugal process, resulting in a long overall sample inspection time and high labor costs.

[0004] In summary, when the existing medical testing instruments centrifuge reagents, the weighting process before centrifugation has technical problems such as long time consumption and high labor costs. Utility Model Content

[0005] The technical problem to be solved by the utility model is that when the existing medical testing instruments centrifuge reagents, the weighting process before centrifugation is time-consuming and labor-intensive.

[0006] In order to solve the above problems, the utility model provides a centrifugal automatic balancing device for a porous plate, comprising a variable balancing weight box, a balancing weight platform assembly and a balancing weight adjustment assembly, wherein the balancing weight platform assembly is used to place a porous plate reagent rack to be leveled before centrifugal operation and the variable balancing weight box, and to weigh the porous plate reagent rack and the variable balancing weight box in turn, wherein the variable balancing weight box has a hollow cavity for accommodating a liquid balancing weight matrix, and the balancing weight adjustment assembly automatically adds or subtracts a corresponding amount of liquid balancing weight matrix into or out of the variable balancing weight box according to the weighed size of the balancing weight platform assembly, so as to adjust the weight of the variable balancing weight box so that its weight is consistent with the weight of the porous plate reagent rack.

[0007] The centrifugal automatic balancing device for a porous plate provided by the utility model replaces the weight balancing process before the reagent centrifugal operation by human labor through an automated design, places the porous plate reagent rack to be weighed and balanced through a weight balancing platform component, thereby obtaining its deadweight, and correspondingly increases or decreases the weight of a variable weight balancing box with reference to this value, wherein a liquid weight balancing matrix is ​​used as the actual carrier for weight increase or decrease, a cavity is set in the variable weight balancing box to accommodate the liquid weight balancing matrix, and the weight is reduced by absorbing the matrix in the cavity through the weight balancing adjustment component, and the weight is increased by injecting liquid, and the process of adjusting the weight balancing ensures that the weight balancing box is located above the weight balancing platform component and weighed in real time, so as to ensure that the weight of the weight balancing box is accurately adjusted, so as to finally make the weight of the weight balancing box equal to the weight of the porous plate reagent rack, and the scheme realizes automatic weight balancing before the centrifugal process, improves the weight balancing efficiency, and does not require human operation, and effectively solves the technical problems of the weight balancing process before centrifugation of the existing medical testing instruments when the reagents are centrifuged, which is time-consuming and has high labor costs.

[0008] As a preferred solution, the weighted platform assembly includes a platform plate, a weighing sensor connected to the bottom support of the platform plate, and a support base. The weighing sensor is located between the platform plate and the support base. The platform plate is used to place a multi-well plate reagent rack and a variable weight box. This design optimizes the structural design of the weighted platform assembly, wherein the weighing is specifically performed through the weighing sensor structure, and the pressure of the deadweight is converted into an electrical signal for automatic control.

[0009] As a preferred solution, a sensor protection block and a lower pad are respectively provided on both sides of the bottom of the weighing sensor to protect and support the weighing sensor. This design optimizes the corresponding peripheral structural design of the weighing sensor, and the sensor protection block and the lower pad are used to protect and support it respectively, so as to avoid damage caused by excessive deformation when the load on it is too heavy, and to prevent excessive pressure on the weighing sensor due to system failure or disassembly.

[0010] As a preferred solution, the top end surface of the platform plate is provided with a guiding oblique surface structure that is inclined and sunken from the edge to its center. The inner bottom contour size and shape of the guiding oblique surface structure are consistent with the outer contour of the bottom surface of the variable counterweight box and the multi-porous plate reagent rack, and are used to stabilize the position of the variable counterweight box or the multi-porous plate reagent rack on the platform plate under the action of its own weight. This design optimizes the structural design of the platform plate. By providing a guiding oblique surface structure that is inclined and sunken from the edge to its center, the area above it that can accommodate the counterweight box or reagent rack is increased. The structure placed in it automatically falls into the preset position at the bottom through the action of the inclined surface, so as to ensure that its position on the platform plate does not deviate, and to ensure the accuracy of weighing by the platform plate.

[0011] As a preferred solution, an adjustable transfer column structure is provided between the top surface of the weighing sensor and the bottom surface of the platform plate, and the adjustable transfer column structure includes an adjustment screw for adjusting the angle between the top surface of the weighing sensor and the bottom surface of the platform plate to ensure accurate weighing. This design further optimizes the structure of the weighing platform, and the platform plate and the weighing sensor are supported by the adjustment screws provided on the adjustable transfer column structure. This structure can ensure that the pressure direction of the weighing sensor is vertical, thereby ensuring weighing accuracy.

[0012] As a preferred solution, the variable counterweight box includes a counterweight box base and a counterweight cover located at the top of the counterweight box base, the hollow cavity is located in the counterweight box base, the counterweight cover is provided with a through injection hole, the injection hole is connected to the hollow cavity, and the counterweight adjustment component increases or decreases liquid in the hollow cavity through the injection hole. This design provides a variable counterweight box design, which mainly includes a base and a cover plate, the internal cavity is shielded by the cover plate, and an injection hole is provided on the top of the cover plate to increase or decrease the counterweight liquid in the cavity.

[0013] As a preferred solution, a sealing ring structure is provided between the weight cover and the weight box base to seal the liquid weight matrix in the hollow cavity to prevent overflow. This design optimizes the sealing of the cavity in the weight box, and prevents the weight liquid injected into the interior from overflowing through the sealing ring structure.

[0014] As a preferred solution, the counterweight adjustment component includes a liquid sample adding mechanism and a peristaltic pump mechanism connected to the liquid sample adding mechanism, the liquid sample adding mechanism includes a lifting arm and a sample adding needle, and the peristaltic pump mechanism drives the sample adding needle to absorb or discharge the liquid counterweight matrix in the hollow cavity. This design provides a preferred structure of the counterweight adjustment component in the device, where the peristaltic pump is used to absorb and discharge the liquid counterweight matrix, wherein the sample adding needle can be inserted into or pulled out of the injection hole on the counterweight cover through the structure of the lifting arm, so as to avoid the position change of the counterweight box being blocked by the completion of the filling.

[0015] As a preferred solution, the centrifugal automatic balancing device for the multi-well plate further includes a manipulator assembly, which is used to take and place the multi-well plate reagent rack and the variable weight box to be balanced from the weight platform assembly according to preset steps. This design further optimizes the overall automatic control of the device, and a special manipulator is set to take and place the reagent rack or the weight box, which is convenient for continuous control of the process action. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the overall structure of a centrifugal automatic balancing device for a porous plate provided by the utility model;

[0017] Figure 2 for Figure 1A schematic diagram of the structure of a variable weight box of a centrifugal automatic balancing device for a medium porous plate;

[0018] Figure 3 for Figure 1 A schematic diagram of the structure of the centrifugal automatic balancing device for a medium-well plate when weighing a multi-well plate reagent rack.

[0019] in, Figure 1-Figure 3 middle:

[0020] 1. Variable counterweight box; 1-1. Hollow cavity; 1-2. Counterweight box base; 1-3. Counterweight cover; 1-4. Injection hole; 1-5. Sealing ring structure; 2. Counterweight platform assembly; 2-1. Platform plate; 2-2. Weighing sensor; 2-3. Support base; 2-4. Lower pad; 2-5. Sensor protection block; 2-6. Guide bevel surface structure; 3. Counterweight adjustment assembly; 3-1. Lifting arm; 3-2. Sample injection needle; 3-3. Peristaltic pump mechanism; 4. Multi-well plate reagent rack. DETAILED DESCRIPTION

[0021] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0022] Before explaining the working principle of the present invention in detail, the description of the present invention needs to be further explained: In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, which are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0023] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, a direct connection, an indirect connection through an intermediate medium, or a welding connection between two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0024] refer to Figure 1-Figure 3 The following embodiments are described, Figure 1This is a schematic diagram of the overall structure of a centrifugal automatic balancing device for a porous plate provided by the utility model; Figure 2 for Figure 1 A schematic diagram of the structure of a variable weight box of a centrifugal automatic balancing device for a medium porous plate; Figure 3 for Figure 1 A schematic diagram of the structure of the centrifugal automatic balancing device for a medium-well plate when weighing a multi-well plate reagent rack.

[0025] The centrifugal automatic balancing device for a porous plate provided in this embodiment includes a variable balancing weight box 1, a balancing weight platform assembly 2 and a balancing weight adjustment assembly 3. The balancing weight platform assembly 2 is used to place a porous plate reagent rack 4 to be balanced before centrifugal operation and a variable balancing weight box 1, and to weigh the porous plate reagent rack 4 and the variable balancing weight box 1 in turn. The variable balancing weight box 1 has a hollow cavity 1-1 for accommodating a liquid balancing weight matrix. The balancing weight adjustment assembly 3 automatically adds or subtracts a corresponding amount of liquid balancing weight matrix into the variable balancing weight box 1 according to the weighing size of the balancing weight platform assembly 2, so as to adjust the weight of the variable balancing weight box 1 so that its weight is consistent with the weight of the porous plate reagent rack 4.

[0026] The centrifugal automatic balancing device for a porous plate provided by the utility model replaces the weight balancing process before the reagent centrifugal operation by human labor through an automated design, places the porous plate reagent rack 4 to be weighed and balanced through the weight balancing platform component 2, thereby obtaining its deadweight, and correspondingly increases or decreases the weight of the variable weight balancing box 1 with reference to this value, wherein a liquid weight balancing matrix is ​​used as the actual carrier for weight increase or decrease, a cavity is set in the variable weight balancing box 1 to accommodate the liquid weight balancing matrix, and the weight is reduced by absorbing the matrix in the cavity through the weight balancing adjustment component 3, and the weight is increased by injecting liquid, and the process of adjusting the weight balancing ensures that the weight balancing box is located above the weight balancing platform component 2 and weighed in real time, so as to ensure that the weight of the weight balancing box is accurately adjusted, so that the weight of the weight balancing box is finally equal to the weight of the porous plate reagent rack 4, and the scheme realizes automatic weight balancing before the centrifugal process, improves the weight balancing efficiency, and does not require human operation, and effectively solves the technical problems of the weight balancing process before centrifugation of the existing medical testing instruments when the reagents are centrifuged, which is time-consuming and has high labor costs.

[0027] In the technical solution provided in this embodiment, the weighted platform assembly 2 includes a platform plate 2-1, a weighing sensor 2-2 connected to the bottom support of the platform plate 2-1, and a support base 2-3, wherein the weighing sensor 2-2 is located between the platform plate 2-1 and the support base 2-3, and the platform plate 2-1 is used to place the multi-well plate reagent rack 4 and the variable weight box 1. This design optimizes the structural design of the weighted platform assembly 2, wherein the weighing is specifically performed through the weighing sensor 2-2, and the pressure of the dead weight is converted into an electrical signal for easy automatic control.

[0028] In the technical solution provided in this embodiment, a sensor protection block 2-5 and a lower pad 2-4 are respectively provided on both sides of the bottom of the weighing sensor 2-2 to protect and support the weighing sensor 2-2. This design optimizes the corresponding peripheral structural design of the weighing sensor 2-2, and the sensor protection block 2-5 and the lower pad 2-4 are used to protect and support it respectively, so as to avoid damage caused by excessive deformation when the load on it is too heavy, and to prevent excessive pressure on the weighing sensor 2-2 due to system failure or disassembly.

[0029] In the technical solution provided in this embodiment, the top end surface of the platform plate 2-1 is provided with a guiding oblique surface structure 2-6 that is inclined and sunken from the edge to its center. The inner bottom contour size and shape of the guiding oblique surface structure 2-6 are consistent with the outer contour of the bottom surface of the variable counterweight box 1 and the porous plate reagent rack 4, and are used to stabilize the position of the variable counterweight box 1 or the porous plate reagent rack 4 on the platform plate 2-1 under the action of its own weight. This design optimizes the structural design of the platform plate 2-1. By setting a guiding oblique surface structure 2-6 that is inclined and sunken from the edge to its center, the area above it that can accommodate the counterweight box or the reagent rack is increased. The structure placed in it automatically falls into the preset position at the bottom through the action of the inclined surface, so as to ensure that its position on the platform plate 2-1 does not deviate, and to ensure the accuracy of weighing through the platform plate 2-1.

[0030] In the technical solution provided in this embodiment, an adjustable adapter column structure is provided between the top surface of the weighing sensor 2-2 and the bottom surface of the platform plate 2-1. The adjustable adapter column structure includes an adjustment screw for adjusting the angle between the top surface of the weighing sensor 2-2 and the bottom surface of the platform plate 2-1 to ensure accurate weighing. This design further optimizes the structure of the weighing platform. Through the adjustment screws provided on the adjustable adapter column structure, a support is formed between the platform plate 2-1 and the weighing sensor 2-2. Through this structure, the verticality of the pressure direction of the weighing sensor 2-2 can be ensured, thereby ensuring weighing accuracy.

[0031] In the technical solution provided in this embodiment, the variable counterweight box 1 includes a counterweight box base 1-2 and a counterweight cover 1-3 located at the top of the counterweight box base 1-2, the hollow cavity 1-1 is located in the counterweight box base 1-2, the counterweight cover 1-3 is provided with a through injection hole 1-4, the injection hole 1-4 is connected to the hollow cavity 1-1, and the counterweight adjustment component 3 increases or decreases liquid in the hollow cavity 1-1 through the injection hole 1-4. This design provides a variable counterweight box 1 design, which mainly includes a base and a cover plate, the internal cavity is shielded by the cover plate, and the injection hole 1-4 is provided on the top of the cover plate to increase or decrease the counterweight liquid in the cavity.

[0032] In the technical solution provided in this embodiment, a sealing ring structure 1-5 is provided between the weight cover 1-3 and the weight box base 1-2, which is used to seal the liquid weight matrix in the hollow cavity 1-1 to prevent overflow. This design optimizes the sealing of the cavity in the weight box, and prevents the weight liquid injected into the inside from overflowing through the structure of the sealing ring.

[0033] In the technical solution provided in this embodiment, the counterweight adjustment component 3 includes a liquid sample adding mechanism and a peristaltic pump mechanism 3-3 connected to the liquid sample adding mechanism, the liquid sample adding mechanism includes a lifting arm 3-1 and a sample adding needle 3-2, and the peristaltic pump mechanism 3-3 drives the sample adding needle 3-2 to absorb or discharge the liquid counterweight matrix in the hollow cavity 1-1. This design provides a preferred structure of the counterweight adjustment component 3 in the device, and provides the absorption and discharge of the liquid counterweight matrix through the peristaltic pump, wherein the sample adding needle 3-2 can be inserted into or pulled out of the injection hole 1-4 on the counterweight cover 1-3 through the structure of the lifting arm 3-1, so as to avoid the position change of the counterweight box blocked by the completion of the filling, and the sample adding needle 3-2 is inserted into the injection hole 1-4 of the counterweight cover 1-3 to a certain depth and does not move, at which time the needle tip is close to the bottom of the cavity in the counterweight box but does not touch it, and the liquid is sucked and discharged by the peristaltic pump component.

[0034] In the technical solution provided in this embodiment, the centrifugal automatic balancing device for a multi-well plate further includes a manipulator assembly, which is used to take and place the multi-well plate reagent rack 4 to be balanced and the variable weight box 1 from the weight platform assembly 2 according to preset steps. This design further optimizes the overall automatic control of the device, and a special manipulator is set to take and place the reagent rack or the weight box, which is convenient for continuous control of the process action.

[0035] The balancing device in each of the above embodiments is generally used in the following specific processes: the manipulator transports the porous plate reagent rack 4 to the counterweight platform and automatically aligns it through the counterweight platform, obtains the total weight of the liquid inside the porous plate reagent rack 4 through the weighing sensor 2-2 at the bottom, and after obtaining the total weight value, the manipulator removes the porous plate reagent rack 4, and moves the counterweight box assembly to the counterweight platform and automatically aligns it. The peristaltic pump component and the sample adding needle 3-2 are used to balance the total weight of the liquid in the counterweight box component so that it is consistent with the weight of the porous plate reagent rack 4, so as to complete the balancing for the work of the adapted centrifuge.

[0036] Although the disclosure is disclosed as above, the protection scope of the disclosure is not limited thereto. Those skilled in the art can make various changes and modifications without departing from the spirit and scope of the disclosure, and these changes and modifications will fall within the protection scope of the utility model.

Claims

1. A centrifugal automatic balancing device for a porous plate, characterized in that: The invention comprises a variable counterweight box (1), a counterweight platform component (2) and a counterweight adjustment component (3); the counterweight platform component (2) is used to place a multi-well plate reagent rack (4) to be leveled before centrifugal operation and the variable counterweight box (1), and to weigh the multi-well plate reagent rack (4) and the variable counterweight box (1) in sequence; the variable counterweight box (1) has a hollow cavity (1-1) for accommodating a liquid counterweight matrix; the counterweight adjustment component (3) automatically adds or removes a corresponding amount of liquid counterweight matrix into the variable counterweight box (1) according to the weighed size of the counterweight platform component (2), so as to adjust the weight of the variable counterweight box (1) so that its weight is consistent with the weight of the multi-well plate reagent rack (4).

2. The centrifugal automatic balancing device for a porous plate according to claim 1, characterized in that: The counterweight platform assembly (2) comprises a platform plate (2-1), a weighing sensor (2-2) connected to the bottom support of the platform plate (2-1), and a support base (2-3); the weighing sensor (2-2) is located between the platform plate (2-1) and the support base (2-3); and the platform plate (2-1) is used to place a multi-well plate reagent rack (4) and a variable counterweight box (1).

3. The centrifugal automatic balancing device for a porous plate according to claim 2, characterized in that: A sensor protection block (2-5) and a lower cushion block (2-4) are respectively arranged on both sides of the bottom of the weighing sensor (2-2) for protecting and supporting the weighing sensor (2-2).

4. The centrifugal automatic balancing device for a porous plate according to claim 2, characterized in that: The top end surface of the platform plate (2-1) is provided with a guiding oblique surrounding surface structure (2-6) which is inclined and sunken from the edge toward the center thereof, and the inner bottom contour size and shape of the guiding oblique surrounding surface structure (2-6) are consistent with the bottom surface outer contour of the variable counterweight box (1) and the multi-well plate reagent rack (4), and are used to stabilize the position of the variable counterweight box (1) or the multi-well plate reagent rack (4) on the platform plate (2-1) under the action of its own weight.

5. The centrifugal automatic balancing device for a porous plate according to claim 4, characterized in that: An adjustable adapter column structure is provided between the top surface of the weighing sensor (2-2) and the bottom surface of the platform plate (2-1), and the adjustable adapter column structure comprises an adjusting screw for adjusting the angle between the top surface of the weighing sensor (2-2) and the bottom surface of the platform plate (2-1) to ensure accurate weighing.

6. The centrifugal automatic balancing device for a porous plate according to any one of claims 1 to 5, characterized in that: The variable counterweight box (1) comprises a counterweight box base (1-2) and a counterweight cover (1-3) located at the top of the counterweight box base (1-2); the hollow cavity (1-1) is located in the counterweight box base (1-2); the counterweight cover (1-3) is provided with a through injection hole (1-4); the injection hole (1-4) is connected to the hollow cavity (1-1); the counterweight adjustment component (3) increases or decreases liquid in the hollow cavity (1-1) through the injection hole (1-4).

7. The centrifugal automatic balancing device for a porous plate according to claim 6, characterized in that: A sealing ring structure (1-5) is provided between the weight cover (1-3) and the weight box base (1-2) for sealing the liquid weight matrix in the hollow cavity (1-1) to prevent overflow.

8. The centrifugal automatic balancing device for a porous plate according to claim 6, characterized in that: The counterweight adjustment component (3) comprises a liquid loading mechanism and a peristaltic pump mechanism (3-3) connected to the liquid loading mechanism, the liquid loading mechanism comprises a lifting arm (3-1) and a loading needle (3-2), and the peristaltic pump mechanism (3-3) drives the loading needle (3-2) to absorb or discharge a liquid counterweight matrix in the hollow cavity (1-1).

9. The centrifugal automatic balancing device for a porous plate according to claim 8, characterized in that: The centrifugal automatic balancing device for a multi-well plate also includes a manipulator assembly, which is used to take and place the multi-well plate reagent rack (4) to be balanced and the variable balancing weight box (1) from the balancing weight platform assembly (2) according to preset steps.

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