Detection device

Abstract

The utility model relates to a detection device which is used for being connected with a liquid suction needle in series so as to receive liquid from the liquid suction needle, and the detection device comprises a flow guide mechanism which is provided with a flow guide hole for liquid circulation and is provided with a smooth flow guide surface for defining part of the boundary of the flow guide hole; the detection mechanism comprises a transmitting unit and a receiving unit which are arranged on the flow guide mechanism, the transmitting unit and the receiving unit are arranged in a spaced mode in the direction forming an acute angle with the flow guide face, and the flow guide hole is located between the transmitting unit and the receiving unit; when the light emitted by the emitting unit can be received by the receiving unit through the flow guide face, the flow guide hole is filled with liquid, and it is judged that the liquid suction needle is not blocked; when the light emitted by the emitting unit can be reflected by the flow guide face and not received by the receiving unit, the flow guide hole is not filled with liquid, and it is judged that the liquid suction needle is blocked. Therefore, the operation convenience and the detection accuracy of the detection device can be improved.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a detection device. Background Art

[0002] In in vitro diagnostic technology, it is usually necessary to add reagents and samples such as human body fluids into a reaction cup for reaction for subsequent detection, and it is also necessary to absorb the waste liquid generated after the reaction of the reagents and samples through a pipette needle and discharge it all into the reaction cup. In view of the complex composition of human body fluids, the pipette needle may be blocked, making it impossible for the pipette needle to absorb liquid from the reaction cup or to discharge the liquid in the pipette needle. Therefore, a detection device is required to detect whether the pipette needle is blocked. However, for traditional detection devices, there are usually defects such as complex detection procedures or low detection accuracy. Summary of the invention

[0003] A technical problem solved by the present application is how to improve the convenience of operation and detection accuracy of the detection device.

[0004] A detection device, used to be connected in series with a liquid aspiration needle to receive liquid from the liquid aspiration needle, the detection device comprising:

[0005] A flow guiding mechanism, provided with a flow guiding hole for liquid circulation, the flow guiding mechanism having a smooth flow guiding surface defining a portion of the flow guiding hole; and

[0006] The detection mechanism comprises a transmitting unit and a receiving unit arranged on the flow guiding mechanism, wherein the transmitting unit and the receiving unit are arranged at intervals along a direction forming an acute angle with the flow guiding surface, and the flow guiding hole is located between the transmitting unit and the receiving unit;

[0007] Among them, when the light emitted by the emitting unit can be received by the receiving unit through the guide surface, the guide hole is full of liquid, and it is determined that the pipette needle is not blocked; when the light emitted by the emitting unit can be reflected by the guide surface but not received by the receiving unit, the guide hole is not full of liquid, and the pipette needle is determined to be blocked.

[0008] In one embodiment, the cross-section of the guide hole is polygonal.

[0009] In one embodiment, the cross-section of the guide hole is rectangular.

[0010] In one of the embodiments, the acute angle formed by the spacing direction between the transmitting unit and the receiving unit and the guide surface ranges from 30° to 60°.

[0011] In one of the embodiments, the acute angle formed by the spacing direction between the transmitting unit and the receiving unit and the guide surface is 45°.

[0012] In one embodiment, the flow guide mechanism includes a flow guide base and a flow guide top cover, the detection mechanism is connected to the flow guide base, the flow guide hole is at least partially located on the flow guide base, a liquid inlet hole is provided on the flow guide base, a liquid outlet hole is provided on the flow guide top cover, and the flow guide hole is connected between the liquid inlet hole and the liquid outlet hole.

[0013] In one of the embodiments, the diversion base and the diversion top cover are detachably connected.

[0014] In one of the embodiments, a mounting hole connected to the guide hole is provided on the guide base, the aperture of the mounting hole is larger than the aperture of the guide hole, the guide top cover includes a large head, a small head and a convex rib, the small head is protruding on the end face of the large head, the cross-sectional size of the large head is larger than the cross-sectional size of the small head, the convex rib is protruding on the outer surface of the small head, a guide groove is recessed on the inner wall of the mounting hole, the small head cooperates with the mounting hole, the large head is located outside the mounting hole and abuts against the guide base, and the convex rib cooperates with the guide groove.

[0015] In one of the embodiments, a first groove and a second groove which are spaced apart are formed on the guide base, the transmitting unit is located in the first groove, and the receiving unit is located in the second groove.

[0016] In one embodiment, at least one of the following schemes is also included:

[0017] The liquid inlet hole comprises a first liquid inlet section and a second liquid inlet section, the aperture of the first liquid inlet section is larger than the aperture of the second liquid inlet section, and the second liquid inlet section is connected between the guide hole and the first liquid inlet section;

[0018] The liquid outlet hole comprises a first liquid outlet section and a second liquid outlet section, the aperture of the first liquid outlet section is larger than the aperture of the second liquid outlet section, and the second liquid outlet section is connected between the guide hole and the first liquid outlet section.

[0019] A technical effect of an embodiment of the present application is that: since the detection mechanism is located outside the guide hole, the detection mechanism is effectively prevented from contacting the liquid, thereby reducing the compatibility requirements of the detection mechanism, thereby reducing the manufacturing cost of the entire detection device. At the same time, by detecting whether there is blockage through reflection and transmission of light, the detection can be carried out in real time, and there is no risk of regular calibration and false alarm, thereby improving the convenience of use and detection accuracy of the detection device. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1A schematic diagram of the three-dimensional structure of a flow guiding mechanism in a detection device provided in an embodiment.

[0021] Figure 2 for Figure 1 The three-dimensional structural schematic diagram of the guide mechanism shown in another viewing angle.

[0022] Figure 3 The present invention is a schematic diagram of a top view of the structure of a detection device provided in an embodiment after removing the guide top cover.

[0023] Figure 4 for Figure 1 A schematic diagram of the three-dimensional cross-sectional structure of the guide base in the guide mechanism shown.

[0024] Figure 5 for Figure 1 A schematic diagram of the three-dimensional cross-sectional structure of the guide mechanism shown.

[0025] Figure 6 for Figure 1 Schematic diagram of the exploded structure of the guide mechanism shown.

[0026] Figure 7 for Figure 6 Schematic diagram of the three-dimensional cross-sectional structure.

[0027] Figure numerals: detection device 10, flow guiding mechanism 100, flow guiding base 110, flow guiding hole 111, flow guiding surface 1111, first groove 112, second groove 113, liquid inlet hole 114, first liquid inlet section 1141, second liquid inlet section 1142, mounting hole 115, guide groove 1151, flow guiding top cover 120, large head 121, small head 122, rib 123, liquid outlet hole 124, first liquid outlet section 1241, second liquid outlet section 1242, detection mechanism 200, transmitting unit 210, receiving unit 220. DETAILED DESCRIPTION

[0028] In order to make the above-mentioned purposes, features and advantages of the present application more obvious and easy to understand, the specific implementation methods of the present application are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present application. However, the present application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present application, so the present application is not limited by the specific embodiments disclosed below.

[0029] In the description of the present application, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application.

[0030] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the description of this application, if the term "plurality" appears, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0031] In this application, unless otherwise clearly specified and limited, if the terms "installed", "connected", "connected", "fixed" and the like appear, these terms should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to the specific circumstances.

[0032] In the present application, unless otherwise clearly specified and limited, if there is a description that a first feature is "above" or "below" a second feature, etc., or similar descriptions appear, it may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0033] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this application are for illustrative purposes only and do not represent the only implementation method.

[0034] See also Figure 1 , Figure 2 and Figure 3 , a detection device 10 provided in one embodiment of the present application is used to detect whether a liquid-pipetting needle is blocked. The detection device 10 can be arranged in series with the liquid-pipetting needle through a pipeline, the liquid-pipetting needle is located upstream, and the detection device 10 is located downstream. After the liquid-pipetting needle absorbs waste liquid from the reaction cup, the liquid-pipetting needle can discharge the waste liquid to the detection device 10 through the pipeline, that is, the detection device 10 can accept waste liquid from the liquid-pipetting needle. Therefore, in the case where the liquid-pipetting needle is not blocked, the liquid-pipetting needle can absorb waste liquid from the reaction cup and discharge the waste liquid to the detection device 10 through the pipeline. At this time, liquid will pass through the detection device 10. In the case where the liquid-pipetting needle is blocked, for example, the blockage occurs before the waste liquid is absorbed, so that the liquid-pipetting needle cannot absorb liquid from the reaction cup, so the liquid-pipetting needle cannot discharge liquid to the detection device 10 through the pipeline. At this time, no liquid passes through the detection device 10. For another example, if the blockage occurs after the waste liquid is sucked and before the waste liquid is discharged, although the liquid-sucking needle can suck the liquid from the reaction cup, it cannot discharge the sucked liquid, which also causes the liquid-sucking needle to be unable to discharge the liquid to the detection device 10 through the pipeline. At this time, no liquid passes through the detection device 10. Of course, in the case of blockage, even if a small amount of liquid enters the detection device 10, the gas-liquid mixture of the fluid flowing in the detection device 10.

[0035] Therefore, the detection principle of the detection device 10 is to determine whether liquid or gas-liquid mixture passes through the detection device 10 to judge whether the aspiration needle is blocked. The detection device 10 includes a flow guiding mechanism 100 and a detection mechanism 200, and the detection mechanism 200 is arranged on the flow guiding mechanism 100.

[0036] See also Figure 1 , Figure 2 and Figure 3 In some embodiments, the detection mechanism 200 may actually be a sensor, and the detection mechanism 200 includes a transmitting unit 210 and a receiving unit 220, which may be spaced apart along the first direction, and the transmitting unit 210 may be a transmitting optical coupler, and the transmitting unit 210 is used to emit light. The receiving unit 220 may be a receiving optical coupler, and the receiving unit 220 is used to receive the light emitted by the transmitting unit 210.

[0037] See also Figure 4 , Figure 5 and Figure 6 In some embodiments, the flow guiding mechanism 100 includes a flow guiding base 110 and a flow guiding top cover 120, and the flow guiding base 110 and the flow guiding top cover 120 are detachably connected, for example, the flow guiding base 110 and the flow guiding top cover 120 can be detachably connected by a snap connection. Of course, the flow guiding base 110 and the flow guiding top cover 120 can also be connected in a non-detachable manner. The flow guiding mechanism 100 is provided with a flow guiding hole 111, and the flow guiding hole 111 can be at least partially located on the flow guiding base 110, for example, the flow guiding hole 111 can be entirely located on the flow guiding base 110, and for example, most of the flow guiding hole 111 is located on the flow guiding base 110, and a small part of the flow guiding hole 111 is located on the flow guiding top cover 120. The flow guiding base 110 is provided with a liquid inlet hole 114, and the flow guiding top cover 120 is provided with a liquid outlet hole 124, and the flow guiding hole 111 is connected between the liquid inlet hole 114 and the liquid storage hole. The extension direction of the liquid outlet hole 124 and the flow guide hole 111 may be the same, for example, the liquid inlet hole 114 and the flow guide hole 111 may be coaxially arranged. The extension direction of the liquid inlet hole 114 may be arranged at an angle to the extension direction of the flow guide hole 111, for example, the extension direction of the liquid inlet hole 114 may be perpendicular to the extension direction of the flow guide hole 111. The liquid from the liquid aspiration needle may enter from the liquid inlet hole 114, and flow out from the liquid outlet hole 124 through the flow guide hole 111.

[0038] See also Figure 4 , Figure 5 and Figure 6In some embodiments, the cross-section of the guide hole 111 may be a polygon, for example, the cross-section of the guide hole 111 may be a rectangle. For another example, the cross-section of the guide hole 111 may be a triangle or a regular polygon. The guide base 110 has a guide surface 1111, which is used to define a portion of the boundary of the guide hole 111. The guide surface 1111 may also be understood as a portion of the inner wall of the guide hole 111. The surface of the guide surface 1111 is extremely smooth, so that the guide surface 1111 can produce mirror reflection of the light reaching the guide surface 1111. Of course, the guide surface 1111 may also be silver-plated to further improve the smoothness and mirror reflection effect of the guide surface 1111. The guide surface 1111 can extend a certain length along the length direction of the guide hole 111, and the spacing direction of the transmitting unit 210 and the receiving unit 220 is the first direction, so that the transmitting unit 210 and the receiving unit 220 are located outside the guide hole 111, and the guide hole 111 is located between the transmitting unit 210 and the receiving unit 220, and the first direction is set at an acute angle with the guide surface 1111. The value range of the acute angle between the first direction and the guide surface 1111 is 30° to 60°, for example, the specific value of the acute angle between the first direction and the guide surface 1111 can be 30°, 45° or 60°, etc.

[0039] See also Figure 4 , Figure 5 and Figure 6 In some embodiments, the flow guide base 110 is provided with a first groove 112 and a second groove 113, and the first groove 112 and the second groove 113 are both located outside the flow guide hole 111, so that the first groove 112 and the second groove 113 are not connected to the flow guide hole 111. The transmitting unit 210 can be arranged in the first groove 112, so that the transmitting unit 210 makes full use of the existing space of the first groove 112, and avoids the transmitting unit 210 occupying as little space outside the first groove 112 as possible, so that the entire detection device 10 is more compact in structure. The receiving unit 220 can be arranged in the second groove 113, so that the receiving unit 220 makes full use of the existing space of the second groove 113, and avoids the receiving unit 220 occupying as little space outside the second groove 113 as possible, so that the entire detection device 10 is more compact in structure. When the transmitting unit 210 emits light, the light generated by the transmitting unit 210 can reach the flow guide surface 1111 along the first direction.

[0040] In some embodiments, the liquid inlet hole 114 includes a first liquid inlet section 1141 and a second liquid inlet section 1142, and the aperture of the first liquid inlet section 1141 is larger than the aperture of the second liquid inlet section 1142. The second liquid inlet section 1142 is provided on the bottom wall surface of the first liquid inlet section 1141, and the portion of the bottom wall surface where the second liquid inlet section 1142 is not provided will form a step surface arranged around the second liquid inlet section 1142. The first liquid inlet section 1141 and the second liquid inlet section 1142 can be arranged coaxially, so that the entire liquid inlet hole 114 is a step hole. The liquid inlet hole 114 can be installed with an external pipeline, so that the liquid discharged by the liquid aspiration needle enters the guide hole 111 through the liquid inlet hole 114.

[0041] In some embodiments, a mounting hole 115 is provided on the flow guide base 110, and the flow guide hole 111 can be located between the mounting hole 115 and the liquid inlet hole 114. The mounting hole 115 can be coaxially arranged with the flow guide hole 111, and the flow guide hole 111 can be provided on the bottom wall surface of the mounting hole 115, and the portion of the bottom wall surface where the flow guide hole 111 is not provided will form a step surface arranged around the flow guide hole 111, so that the mounting hole 115 and the flow guide hole 111 form a step hole. Obviously, the aperture of the mounting hole 115 is larger than the aperture of the flow guide hole 111. A guide groove 1151 is formed in a depression on the inner wall surface of the mounting hole 115.

[0042] See also Figure 5 , Figure 6 and Figure 7 The diversion top cover 120 includes a large head 121, a small head 122 and a convex rib 123. The large head 121 and the small head 122 can be coaxially arranged so that the small head 122 is arranged on the end surface of the large head 121 along the axial direction of the large head 121. The cross-sectional size of the large head 121 is larger than the cross-sectional size of the small head 122, so that the large head 121 and the small head 122 are connected to form a shape similar to a stepped shaft. The convex rib 123 is arranged on the outer surface of the small head 122 along the radial direction of the small head 122. The cross-sectional size of the large head 121 is larger than the aperture of the mounting hole 115, and the cross-sectional size of the small head 122 can be roughly equivalent to the aperture of the mounting hole 115. During the installation process of the diversion top cover 120 and the diversion base 110, the small head 122 can be inserted into the mounting hole 115, and the convex rib 123 cooperates with the guide groove 1151. The cooperation between the rib 123 and the guide groove 1151 can ensure that the diversion top cover 120 is fixed on the diversion base 110 in the correct installation orientation, thereby improving the assembly efficiency and accuracy of the diversion top cover 120. The small head 122 can abut against the bottom wall of the installation hole 115, and the large head 121 is located outside the installation hole 115 and can abut against the end surface of the diversion base 110.

[0043] In some embodiments, the liquid outlet hole 124 includes a first liquid outlet section 1241 and a second liquid outlet section 1242, and the aperture of the first liquid outlet section 1241 is larger than the aperture of the second liquid outlet section 1242. The second liquid outlet section 1242 is arranged on the bottom wall surface of the first liquid outlet section 1241, and the portion of the bottom wall surface where the second liquid outlet section 1242 is not arranged will form a step surface arranged around the second liquid outlet section 1242. The first liquid outlet section 1241 and the second liquid outlet section 1242 can be arranged coaxially, so that the entire liquid outlet hole 124 is a step hole. The liquid in the guide hole 111 can be discharged to the outside of the detection device 10 through the liquid outlet hole 124.

[0044] The working principle of the detection device 10 is described below: Taking the guide surface 1111 as an example, the angle between the guide surface 1111 and the first direction is 45°, the emitting unit 210 emits light along the first direction. When there is no liquid or a gas-liquid mixture in the guide hole 111, the incident light ( Figure 3 When the solid arrow in the middle reaches the guide surface 1111, the guide surface 1111 will reflect the incident light to form a reflected light ( Figure 3 In this case, the reflected light will be emitted in the second direction. Obviously, the second direction is perpendicular to the first direction, so that the receiving unit 220 cannot receive the light emitted in the second direction. Therefore, the detection mechanism 200 will determine that the pipette needle does not supply liquid to the detection device 10 at all, or the pipette needle supplies a small amount of liquid to the detection device 10 to form a gas-liquid mixture, so that the detection device 10 will determine that the pipette needle is blocked. When the guide hole 111 is full of liquid, when the incident light emitted by the emitting unit 210 reaches the guide surface 1111, the guide surface 1111 will lose its reflection function for light under the action of the liquid, so that the incident light passes through the liquid in the guide hole 111 to form a transmitted light ( Figure 3 The transmitted light continues to propagate in a straight line along the first direction, so the light propagating in a straight line along the first direction will reach the receiving unit 220 to be absorbed by the receiving unit 220. Therefore, the detection mechanism 200 will determine that the liquid pipetting needle supplies enough liquid to the detection device 10, so that the detection device 10 will determine that the liquid pipetting needle is not blocked.

[0045] For traditional detection devices, if a pressure sensor is used to detect whether it is blocked, however, the pressure sensor will be in direct contact with the liquid in the detection device, so the chemical compatibility requirements of the pressure sensor are extremely high, thereby increasing the manufacturing cost of the pressure sensor and the entire detection device. And the signal of the pressure sensor needs to be filtered and amplified, which is not conducive to the convenience of the detection device. At the same time, the detection signal of the pressure sensor drifts, and the pressure sensor needs to be calibrated regularly, which is also not conducive to the convenience of the detection device 10 operation, and also affects the detection accuracy of the detection device. If an optical coupler is set, the light of the optical coupler is blocked by the liquid and changes, so that the flow channel of the detection device is detected to detect the presence of liquid or gas-liquid mixture, but due to the reason of light transmittance, the optical coupler also needs to be calibrated regularly, which will also affect the convenience of operation and detection accuracy. At the same time, it is also necessary to eliminate the interference of the signal to amplify the signal, thereby increasing the use cost of the detection device. If the pipette needle is blocked by detecting whether there is liquid in the reaction cup, it is not possible to achieve real-time monitoring, and a specific detection process is also required for identification, which will also affect the detection accuracy.

[0046] As for the detection device 10 in the above embodiment, since the detection mechanism 200 is located outside the guide hole 111, the detection mechanism 200 is effectively prevented from contacting with the liquid, thereby reducing the compatibility requirements of the detection mechanism 200, thereby reducing the manufacturing cost of the entire detection device 10. At the same time, by detecting whether there is blockage through reflection and transmission of light, the detection can be performed in real time, and there is no risk of regular calibration and false alarm, thereby improving the convenience of use and detection accuracy of the detection device 10.

[0047] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0048] The above-described embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be construed as limiting the scope of the patent application. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent application shall be subject to the attached claims.

Claims

1. A detection device, used to be connected in series with a liquid aspiration needle to receive liquid from the liquid aspiration needle, characterized in that: The detection device comprises: A flow guiding mechanism, provided with a flow guiding hole for liquid circulation, the flow guiding mechanism having a smooth flow guiding surface defining a portion of the flow guiding hole; and The detection mechanism comprises a transmitting unit and a receiving unit arranged on the flow guiding mechanism, wherein the transmitting unit and the receiving unit are arranged at intervals along a direction forming an acute angle with the flow guiding surface, and the flow guiding hole is located between the transmitting unit and the receiving unit; Among them, when the light emitted by the emitting unit can be received by the receiving unit through the guide surface, the guide hole is full of liquid, and it is determined that the pipette needle is not blocked; when the light emitted by the emitting unit can be reflected by the guide surface but not received by the receiving unit, the guide hole is not full of liquid, and the pipette needle is determined to be blocked.

2. The detection device according to claim 1, characterized in that: The cross section of the guide hole is polygonal.

3. The detection device according to claim 2, characterized in that: The cross section of the guide hole is rectangular.

4. The detection device according to claim 1, characterized in that: The acute angle formed by the spacing direction between the transmitting unit and the receiving unit and the guide surface ranges from 30° to 60°.

5. The detection device according to claim 4, characterized in that: The acute angle formed by the spacing direction between the transmitting unit and the receiving unit and the guide surface is 45°.

6. The detection device according to claim 1, characterized in that: The flow guide mechanism includes a flow guide base and a flow guide top cover, the detection mechanism is connected to the flow guide base, the flow guide hole is at least partially located on the flow guide base, a liquid inlet hole is provided on the flow guide base, a liquid outlet hole is provided on the flow guide top cover, and the flow guide hole is connected between the liquid inlet hole and the liquid outlet hole.

7. The detection device according to claim 6, characterized in that: The diversion base and the diversion top cover are detachably connected.

8. The detection device according to claim 6, characterized in that: The guide base is provided with a mounting hole connected with the guide hole, the aperture of the mounting hole is larger than the aperture of the guide hole, the guide top cover includes a large head, a small head and a convex rib, the small head is protrudingly arranged on the end surface of the large head, the cross-sectional size of the large head is larger than the cross-sectional size of the small head, the convex rib is protrudingly arranged on the outer surface of the small head, a guide groove is formed on the inner wall of the mounting hole, the small head cooperates with the mounting hole, the large head is located outside the mounting hole and abuts against the guide base, and the convex rib cooperates with the guide groove.

9. The detection device according to claim 6, characterized in that: The guide base is provided with a first groove and a second groove which are spaced apart from each other. The transmitting unit is located in the first groove, and the receiving unit is located in the second groove.

10. The detection device according to claim 6, characterized in that: Also includes at least one of the following options: The liquid inlet hole comprises a first liquid inlet section and a second liquid inlet section, the aperture of the first liquid inlet section is larger than the aperture of the second liquid inlet section, and the second liquid inlet section is connected between the guide hole and the first liquid inlet section; The liquid outlet hole comprises a first liquid outlet section and a second liquid outlet section, the aperture of the first liquid outlet section is larger than the aperture of the second liquid outlet section, and the second liquid outlet section is connected between the guide hole and the first liquid outlet section.

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