Tangential flow biological separation and purification membrane package clamp filtering device
By designing an inclined inlet flow channel and return channel in the tangential flow membrane clamp, the automatic gathering and exhaustion of the material liquid is achieved, and the problem of material liquid retention in the prior art is solved, and the cleanliness of the process and the service life of the film packet are improved.
Patent Information
- Application Number
- CN202421297490.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-07
- Publication Date
- 2025-03-25
- Estimated Expiration
- 2034-06-07
AI Technical Summary
The existing tangential flow film clamps cannot effectively drain the material liquid, resulting in cleanliness and hygiene problems in the separation and purification process. The material liquid will corrode the film after it drys up, affecting its service life.
A tangential flow biological separation and purification membrane clamp filter device is designed. By setting an inclined inlet flow channel and return channel between the material liquid distribution base and the membrane bag, the residual material liquid is automatically gathered to the lowest point of the system by gravity, so as to achieve complete exhaustion of the material liquid.
It effectively solves the problem of material liquid retention in the membrane bag, improves the cleanliness and hygiene of the separation and purification process, extends the service life of the membrane bag, and improves the utilization rate of the material liquid.
Smart Images

Figure CN222658326U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of biological filtration devices, and in particular relates to a tangential flow biological separation and purification membrane package clamp filtration device. Background Art
[0002] Tangential flow filtration is a commonly used filtration operation in pharmaceutical processes. It is widely used in processes such as clarification filtration, product concentration, pyrogen removal, small molecule impurity removal, desalination and buffer exchange. Tangential flow filtration refers to the flow direction of the liquid being parallel to the membrane surface. Under the action of pressure, only a part of the liquid passes through the filter membrane and enters the downstream. This operation mode is called "cross-flow filtration". The tangential flow continuously "flushes" the surface of the membrane package during the filtration process, effectively alleviating the accumulation of large particles on the membrane. This operation has unique advantages in many applications. At present, the tangential flow membrane package clamps on the market basically cannot effectively drain the feed liquid. The retention of feed liquid in the membrane package not only affects the cleanliness and hygiene of the separation and purification process, but also the dried feed liquid will produce fixed residues, which will corrode the membrane package and affect the service life of the membrane package. Utility Model Content
[0003] In view of the above problems and technical requirements, the utility model provides a tangential flow biological separation and purification membrane package clamp filtration device. After the tangential flow process is stopped, the device can automatically converge all the feed liquid in the entire system to the lowest point of the system to achieve the purpose of draining the feed liquid.
[0004] The technical scheme of the utility model is as follows: a tangential flow biological separation and purification membrane package clamp filtering device, including a membrane body support mechanism, a membrane package and a liquid distribution base, the membrane body support mechanism includes a plurality of horizontal support frames arranged in sequence along the vertical direction, the vertically arranged liquid distribution base is slidably connected to all the horizontal support frames at the same time, the liquid distribution base can slide left and right along the horizontal support frames, two membrane packages are installed in each horizontal support frame, the two membrane packages are symmetrically connected on the left and right sides of the liquid distribution base, the horizontal support frame can clamp the membrane package and the liquid distribution base, so that the flow channel between the membrane package and the liquid distribution base is sealed and connected; an inlet flow channel and a return flow channel are provided between the liquid distribution base and the membrane package, the inlet flow channel is obliquely upward from the liquid distribution base to the lowest point of each membrane package, the return flow channel is arranged at the highest point of the membrane package, and the return flow channel returns obliquely upward from the membrane package to the liquid distribution base. In the above scheme, the liquid inlet channel and the return channel are tilted and set at the lowest and highest points of the membrane package respectively. When the process is terminated, the residual liquid in the membrane package can flow back to the liquid distribution base from the lowest point along the liquid inlet channel, and the liquid can be discharged from the membrane package without remaining in the membrane package.
[0005] Furthermore, the liquid distribution base includes a cabinet, a liquid inlet chamber, a liquid collecting chamber and a reflux chamber. The cabinet is slidably connected to the membrane support mechanism. A liquid collecting chamber is vertically arranged in the middle of the cabinet, and the liquid collecting chamber runs through the top and bottom surfaces of the cabinet. The top of the liquid collecting chamber is a permeation port, and the bottom is a waste water outlet. The waste water outlet is closed under working conditions; the liquid inlet chamber and the reflux chamber are respectively arranged on the front and back sides of the liquid collecting chamber, and the liquid inlet chamber and the reflux chamber are also arranged in a vertical direction. The liquid is injected into the membrane package from the liquid inlet chamber, and the membrane package and the liquid collecting chamber are connected by a liquid collecting flow channel. The liquid collecting flow channel is arranged obliquely downward along the flow direction. The liquid filtered by the membrane package flows into the liquid collecting chamber through the liquid collecting flow channel. After the membrane package is filled with liquid, the liquid flows into the reflux chamber from the reflux channel at the top.
[0006] Furthermore, the liquid inlet cavity is provided with a liquid inlet on the bottom surface of the cabinet, the top of the liquid inlet cavity is closed, and the liquid inlet channel is inclined upward from the side wall of the liquid inlet cavity to the bottom of the membrane package. The feed liquid is injected into the liquid inlet cavity upward from the liquid inlet, and then obliquely enters each membrane package upward. When the process is completed, all the liquid in the membrane package can flow back to the lowest point of the liquid inlet cavity. The collected feed liquid can be automatically emptied as long as the liquid inlet is opened, so that the liquid inlet cavity is kept clean.
[0007] Furthermore, the reflux chamber is provided with a reflux port on the top surface of the cabinet, the bottom of the reflux chamber is closed, and the reflux channel is obliquely upward from the top of the membrane package into the side wall of the reflux chamber. The reflux chamber accumulates the overflowed liquid, and the refluxed and collected liquid flows out again through the reflux port and is collected. The collected liquid can be pumped back into the liquid inlet chamber, and the liquid refluxed multiple times can be further purified, thereby improving the utilization rate of the liquid.
[0008] Furthermore, a liquid collecting channel is provided between the membrane package and the liquid collecting chamber, and the middle part of the membrane package in the liquid collecting channel obliquely passes downward into the side wall of the liquid collecting chamber, and the liquid filtered from the membrane package is collected into the liquid collecting chamber through the liquid collecting channel, and flows out from the top through-port after the liquid collecting chamber is full. The liquid collecting channel is inclined downward, and the water pressure in the membrane package automatically presses the filtered liquid into the liquid collecting channel, and collects it into the liquid collecting chamber along the liquid collecting channel. When the process is terminated, the liquid that has not entered the liquid collecting channel will flow back into the unfiltered side of the membrane package, and flow back into the liquid inlet chamber together with the remaining liquid in the membrane package.
[0009] Furthermore, the horizontal support frame includes a transverse tie rod, a front clamping plate and a back clamping plate. The front clamping plate and the back clamping plate are connected by multiple parallel transverse tie rods. The liquid distribution base is slidably connected to the multiple transverse tie rods. The membrane package is accommodated in the space enclosed by the multiple transverse tie rods. Pressure is applied to the front clamping plate to slide the front clamping plate inward, clamping the membrane package between the back clamping plate, the liquid distribution base and the front clamping plate, so that the membrane package and the liquid distribution base are sealed and connected.
[0010] Furthermore, a push-pull support plate is fixedly connected to the outer side of the front clamping plate, the push-pull support plate is parallel to the front clamping plate, and a hydraulic pushing assembly is installed on the outer side of the push-pull support plate. The hydraulic pushing assembly includes a hydraulic cylinder, a piston rod and a support frame. The piston rod vertically passes through the push-pull support plate to push the front end against the front clamping plate, the tail end of the piston rod of the horizontal support frame of the top layer is connected to the hydraulic cylinder, and multiple piston rods below the top layer are connected through a vertical support frame. The front clamping plate of the top layer is vertically connected to the support frame through a transverse guide rod. The hydraulic cylinder drives the front clamping plate of the top layer to advance inward, and the front clamping plate of the top layer drives all the front clamping plates below to push the material inward synchronously through the transverse guide rod and the support frame to clamp the membrane package.
[0011] Furthermore, each front clamping plate is vertically provided with a transverse guide rod, and the transverse guide rod passes through the push-pull support plate and is fixedly connected to the support frame.
[0012] In the above scheme, a hydraulic cylinder is provided. By connecting the piston rods one by one through the support frame, the hydraulic cylinder can simultaneously push all the front clamping plates to clamp and seal the membrane package. The structure has strong synchronization, and the operation is simpler and energy-saving.
[0013] Furthermore, a plurality of parallel positioning rods are provided between the front clamping plate and the back clamping plate, the positioning rods are connected to the lower parts of the front clamping plate and the back clamping plate, and the membrane packages are placed on the positioning rods accordingly.
[0014] Furthermore, a base bracket is installed at the bottom of the cabinet of the liquid distribution base, and the base bracket raises the cabinet to leave a waste discharge space for the waste water discharge port. After the process is completed, waste water can be discharged through the waste water discharge port.
[0015] Compared with the prior art, the beneficial effects of the utility model are as follows: in the device, the feed liquid is injected into the membrane package from the liquid inlet chamber obliquely upward, and the connection position is at the lowest point of the membrane package. Therefore, once there is residual feed liquid in the membrane package, it will flow back to the liquid inlet chamber along the liquid inlet channel; the feed liquid obtained after filtration in the membrane package is gathered into the liquid collecting chamber through the downward inclined liquid collecting channel. When the feed liquid in the membrane package is full, the excess liquid flows obliquely upward into the reflux chamber from the reflux channel. Since the upper flow channels are all inclined flow channels, when the filtration work is terminated, the liquid in the reflux channel flows back into the membrane package, and the liquid in the membrane package flows to the lowest point of the liquid inlet chamber. All the feed liquid that has been filtered flows into the liquid collecting chamber, and no liquid will remain in the membrane package, which solves the problem that the existing tangential flow biological membrane package cannot drain all the feed liquid, greatly improves the cleanliness and hygiene of the tangential flow separation and purification process, can extract higher quality feed liquid results, and make the process more stable and reliable. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] Figure 1 It is a front view of the tangential flow biological separation and purification membrane package clamp filtering device of the utility model;
[0017] Figure 2 It is a cross-sectional view of the middle part of the liquid distribution base in the utility model;
[0018] Figure 3 It is a front perspective view of the tangential flow biological separation and purification membrane package clamp filtering device of the utility model;
[0019] Figure 4 It is a horizontal cross-sectional view of the tangential flow biological separation and purification membrane package clamp filtering device of the utility model;
[0020] Figure 5 It is a three-dimensional structural diagram of the utility model of the tangential flow biological separation and purification membrane package clamp filtering device;
[0021] Marked in the figure are: liquid distribution base 1, base bracket 11, cabinet 2, liquid inlet chamber 3, liquid inlet channel 31, liquid inlet port 32, liquid collecting chamber 4, liquid collecting channel 41, permeation port 42, waste water outlet 43, reflux chamber 5, reflux channel 51, reflux port 52, membrane package 6, horizontal support frame 7, cross-tie rod 71, front clamping plate 72, back clamping plate 73, positioning rod 74, hydraulic pushing assembly 8, piston rod 81, push-pull support plate 82, support frame 83, cross-guide rod 84. DETAILED DESCRIPTION
[0022] The utility model is further described below in conjunction with the accompanying drawings and embodiments.
[0023] like Figure 1-5 The figure shows a tangential flow bio-separation and purification membrane package clamp filtration device of the utility model, including a membrane body support mechanism, a membrane package 6 and a liquid distribution base 1. The membrane body support mechanism includes a plurality of horizontal support frames 7 arranged in sequence along the vertical direction. The vertically arranged liquid distribution base 1 is slidably connected to all the horizontal support frames 7 at the same time. The liquid distribution base 1 can slide left and right along the horizontal support frames 7. Two membrane packages 6 are installed in each horizontal support frame 7. The two membrane packages 6 are symmetrically connected to the left and right sides of the liquid distribution base 1. The horizontal support frame 7 can clamp the membrane package 6 and the liquid distribution base 1 so that the flow channel between the membrane package 6 and the liquid distribution base 1 is sealed and connected.
[0024] An inlet channel 31 and a return channel 51 are provided between the liquid distribution base 1 and the membrane package 6. The inlet channel 31 is obliquely upwardly connected from the liquid distribution base 1 to the lowest point of each membrane package 6. The return channel 51 is provided at the highest point of the membrane package 6. The return channel 51 returns obliquely upwardly from the membrane package 6 to the liquid distribution base 1. The horizontal support frame 7 includes a transverse tie rod 71, a front clamping plate 72 and a back clamping plate 73. The front clamping plate 72 and the back clamping plate 73 are connected by a plurality of parallel transverse tie rods 71. The liquid distribution base 1 is slidably connected to the plurality of transverse tie rods 71. The membrane package 6 is accommodated in a space enclosed by the plurality of transverse tie rods 71. Pressure is applied to the front clamping plate 72 to slide the front clamping plate 72 inwardly, and the membrane package 6 is clamped between the back clamping plate 72, the liquid distribution base 1 and the front clamping plate 72, so that the membrane package 6 and the liquid distribution base 1 are sealed and connected. Each front clamping plate 72 is vertically provided with a transverse guide rod 84, which passes through the push-pull support plate 82 and is fixedly connected to the support frame 83. A plurality of parallel positioning rods 74 are also provided between the front clamping plate 72 and the back clamping plate 73, and the positioning rods 74 are connected to the lower parts of the front clamping plate 72 and the back clamping plate 73, and the membrane package 6 is placed on the positioning rods 74 accordingly.
[0025] The outer side of the front clamping plate 72 is fixedly connected to a push-pull support plate 82, which is parallel to the front clamping plate 72. A hydraulic pushing assembly 8 is installed on the outer side of the push-pull support plate 82. The hydraulic pushing assembly 8 includes a hydraulic cylinder (not shown in the figure), a piston rod 81 and a support frame 83. The piston rod 81 vertically passes through the push-pull support plate 82 to push the front end against the front clamping plate 72. The tail end of the piston rod 81 of the horizontal support frame 7 of the top layer is connected to the hydraulic cylinder, and multiple piston rods 81 below the top layer are connected through a vertical support frame 83. The front clamping plate 72 of the top layer is vertically connected to the support frame 83 through a transverse guide rod 84. The hydraulic cylinder drives the front clamping plate 72 of the top layer to advance inward. The front clamping plate 72 of the top layer drives all the front clamping plates 72 below to push inward synchronously through the transverse guide rod 84 and the support frame 83 to clamp the membrane package 6.
[0026] The liquid distribution base 1 includes a cabinet 2, a liquid inlet chamber 3, a liquid collecting chamber 4 and a reflux chamber 5. The cabinet 2 is slidably connected to the membrane support mechanism. A liquid collecting chamber 4 is vertically arranged in the middle of the cabinet 2. The liquid collecting chamber 4 runs through the top and bottom surfaces of the cabinet. The top of the liquid collecting chamber 4 is a permeation port 42, and the bottom is a waste water outlet 43. The waste water outlet 43 is closed under working conditions; the liquid inlet chamber 3 and the reflux chamber 5 are respectively arranged on the front and back sides of the liquid collecting chamber 4, and the liquid inlet chamber 3 and the reflux chamber 5 are also arranged in the vertical direction. The liquid is injected into the membrane package 6 from the liquid inlet chamber 3. The membrane package 6 and the liquid collecting chamber 4 are connected by a liquid collecting flow channel 41. The liquid collecting flow channel 41 is arranged obliquely downward along the flow direction. The liquid filtered by the membrane package 6 flows into the liquid collecting chamber 4 through the liquid collecting flow channel 41. After the membrane package 6 is filled with liquid, the liquid flows into the reflux chamber 5 from the reflux channel 51 at the top. A base bracket 11 is installed at the bottom of the cabinet of the liquid distribution base 1, and the base bracket 11 raises the cabinet 2 to leave a waste discharge space for the waste water outlet 43.
[0027] The liquid inlet cavity 3 is provided with a liquid inlet port 32 on the bottom surface of the cabinet, the top of the liquid inlet cavity 3 is closed, and the liquid inlet channel 31 is obliquely upwardly connected to the bottom of the membrane package from the side wall of the liquid inlet cavity 3. The feed liquid is injected into the liquid inlet cavity 3 from the liquid inlet port 32, and then obliquely upwardly enters each membrane package 6. When the process is completed, all the liquid in the membrane package 6 can flow back to the lowest point of the liquid inlet cavity 3. The collected feed liquid can be automatically emptied as long as the liquid inlet port 32 is opened, so that the liquid inlet cavity 3 is kept clean.
[0028] The reflux chamber 5 is provided with a reflux port 52 on the top surface of the cabinet, the bottom of the reflux chamber 5 is closed, and the reflux channel 51 is obliquely upwardly connected from the top of the membrane package 6 into the side wall of the reflux chamber 5. The reflux chamber 5 accumulates the overflowed liquid, and the refluxed and collected liquid flows out again through the reflux port 52 to be collected. The collected liquid can be pumped back into the liquid inlet chamber 3, and the liquid refluxed multiple times can be further purified, thereby improving the utilization rate of the liquid.
[0029] A liquid collecting channel 41 is provided between the membrane package 6 and the liquid collecting chamber 4. The middle part of the membrane package 6 in the liquid collecting channel 41 obliquely passes downward into the side wall of the liquid collecting chamber 4. The liquid filtered from the membrane package 6 is collected in the liquid collecting chamber 4 through the liquid collecting channel 41. When the liquid collecting chamber 4 is full, it flows out from the top through-port 42. The liquid collecting channel 41 is inclined downward, and the water pressure in the membrane package 6 automatically presses the filtered liquid into the liquid collecting channel 41, and collects it into the liquid collecting chamber 4 along the liquid collecting channel 41. When the process is terminated, the liquid that has not entered the liquid collecting channel 41 will flow back into the unfiltered side of the membrane package 6, and flow back into the liquid inlet chamber 3 together with the remaining liquid in the membrane package 6.
[0030] The operation process of the utility model is as follows: the membrane package 6 is placed in the horizontal support frame 7, the positioning rod 74 supports the membrane package 6 from the bottom, the membrane package 6 is positioned, the membrane package 6 is aligned with the side of the liquid distribution base 1, the upper front clamping plate 72 is pushed inward by the hydraulic cylinder, and the support frame 83 simultaneously pushes all piston rods 81 to push the material inward, and the front clamping plate 72, the membrane package 6 and the cabinet of the liquid distribution base 1 are clamped and aligned; the liquid is pumped into the liquid inlet cavity 3 from the liquid inlet port 32, and the liquid is injected into the membrane package 6 obliquely upward from the liquid inlet channel 31 at the bottom of the membrane package. After being filled, the liquid is injected obliquely upward from the reflux channel 51 at the bottom of the membrane package into the reflux cavity 5, and the membrane package 6 is subjected to tangential flow separation and filtration, and the filtered liquid passes through the liquid collecting channel 4 1 is poured obliquely downward into the liquid collecting chamber 4, and when the liquid collecting chamber 4 is filled, it flows out from the permeation port 42 to obtain the filtered product; when the reflux chamber 5 is full, the refluxed liquid enters the pumping system again through the reflux port 52, and the pumping system can send the liquid into the liquid inlet chamber 3 again to filter and purify the liquid multiple times; when the system stops running, the liquid in the reflux chamber 5 flows back to the membrane package 6, and the liquid in the membrane package 6 flows back to the liquid inlet chamber 3 from the lowest liquid inlet channel 31 again, and no liquid is retained in the reflux chamber 5. By opening the liquid inlet port 32 and the waste water outlet 43, the liquid in the liquid inlet chamber 3 and the liquid collecting chamber 4 can be emptied, and the liquid distribution base 1 and all the membrane packages 6 can be completely drained, which greatly increases the cleanliness of the overall system after the tangential flow process.
[0031] The above are only several preferred embodiments of the present invention, but the protection scope of the present invention is not limited thereto. Any changes and substitutions that can be easily thought of by a person skilled in the art within the technical scope disclosed by the present invention should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.
Claims
1. A tangential flow biological separation and purification membrane package clamp filtration device, characterized in that: It includes a membrane support mechanism, a membrane package and a liquid distribution base. The membrane support mechanism includes a plurality of horizontal support frames arranged in sequence along the vertical direction. The vertically arranged liquid distribution base is slidably connected to all the horizontal support frames at the same time. The liquid distribution base can slide left and right along the horizontal support frames. Two membrane packages are installed in each horizontal support frame. The two membrane packages are symmetrically connected on the left and right sides of the liquid distribution base. The horizontal support frame can clamp the membrane package and the liquid distribution base so that the flow channel between the membrane package and the liquid distribution base is sealed and connected; an inlet flow channel and a return flow channel are provided between the liquid distribution base and the membrane package. The inlet flow channel is obliquely upward from the liquid distribution base to the lowest point of each membrane package. The return flow channel is arranged at the highest point of the membrane package. The return flow channel returns obliquely upward from the membrane package to the liquid distribution base.
2. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 1, characterized in that: The liquid distribution base includes a cabinet, a liquid inlet chamber, a liquid collecting chamber and a reflux chamber. The cabinet is slidably connected to the membrane support mechanism. A liquid collecting chamber is vertically arranged in the middle of the cabinet, and the liquid collecting chamber runs through the top and bottom surfaces of the cabinet. The top of the liquid collecting chamber is a permeation port, and the bottom is a waste water outlet. The waste water outlet is closed under working conditions. The liquid inlet chamber and the reflux chamber are respectively arranged on the front and back sides of the liquid collecting chamber, and the liquid inlet chamber and the reflux chamber are also arranged in a vertical direction. The liquid is injected into the membrane package from the liquid inlet chamber, and the membrane package and the liquid collecting chamber are connected by a liquid collecting flow channel. The liquid collecting flow channel is arranged obliquely downward along the flow direction. The liquid filtered by the membrane package flows into the liquid collecting chamber through the liquid collecting flow channel. After the membrane package is filled with liquid, the liquid flows into the reflux chamber from the reflux channel at the top.
3. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 2, characterized in that: The liquid inlet cavity is provided with a liquid inlet on the bottom surface of the cabinet, the top of the liquid inlet cavity is closed, and the liquid inlet flow channel is inclined upward from the side wall of the liquid inlet cavity to the bottom of the membrane package.
4. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 3, characterized in that: The reflux chamber is provided with a reflux port on the top surface of the cabinet, the bottom of the reflux chamber is closed, and the reflux channel is obliquely led upward from the top of the membrane package into the side wall of the reflux chamber.
5. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 4, characterized in that: A liquid collecting channel is provided between the membrane package and the liquid collecting chamber. The middle part of the membrane package in the liquid collecting channel obliquely passes downward into the side wall of the liquid collecting chamber. The liquid filtered from the membrane package is gathered into the liquid collecting chamber through the liquid collecting channel. When the liquid collecting chamber is full, it flows out from the permeation port at the top.
6. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 5, characterized in that: The horizontal support frame includes a transverse tie rod, a front clamping plate and a back clamping plate. The front clamping plate and the back clamping plate are connected by multiple parallel transverse tie rods. The liquid distribution base is slidably connected to the multiple transverse tie rods. The membrane package is accommodated in a space enclosed by the multiple transverse tie rods. Pressure is applied to the front clamping plate to slide the front clamping plate inward, clamping the membrane package between the back clamping plate, the liquid distribution base and the front clamping plate, so that the membrane package and the liquid distribution base are sealed and connected.
7. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 6, characterized in that: The outer side of the front clamping plate is fixedly connected to a push-pull support plate, which is parallel to the front clamping plate. A hydraulic pushing assembly is installed on the outer side of the push-pull support plate. The hydraulic pushing assembly includes a hydraulic cylinder, a piston rod and a support frame. The piston rod vertically passes through the push-pull support plate to push the front end against the front clamping plate. The tail end of the piston rod of the horizontal support frame of the top layer is connected to the hydraulic cylinder, and multiple piston rods below the top layer are connected through a vertical support frame. The front clamping plate of the top layer is vertically connected to the support frame through a transverse guide rod. The hydraulic cylinder drives the front clamping plate of the top layer to advance inward, and the front clamping plate of the top layer drives all the front clamping plates below to push the material inward synchronously through the transverse guide rod and the support frame to clamp the film package.
8. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 7, characterized in that: A transverse guide rod is vertically arranged on each front clamping plate, and the transverse guide rod passes through the push-pull support plate and is fixedly connected to the support frame.
9. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 8, characterized in that: A plurality of parallel positioning rods are also arranged between the front clamping plate and the back clamping plate. The positioning rods are connected to the lower parts of the front clamping plate and the back clamping plate, and the membrane packages are placed on the positioning rods accordingly.
10. A tangential flow biological separation and purification membrane package clamp filtration device according to claim 9, characterized in that: A base bracket is installed at the bottom of the cabinet of the liquid distribution base, and the base bracket raises the cabinet to leave a waste discharge space for the waste water outlet.