DNA (Deoxyribose Nucleic Acid) synthesis plate

Abstract

The utility model discloses a DNA (deoxyribonucleic acid) synthesis plate which comprises a mounting base plate and a plurality of DNA synthesis plate main bodies, the plurality of DNA synthesis plate main bodies are arranged on a mounting groove of the mounting base plate in an inlaying manner, four prepared liquid adding ports and a DNA synthesis groove are arranged on each DNA synthesis plate main body, and a support frame is arranged on the side of the mounting base plate. The DNA synthesis plate is provided with the mounting base plate, the supporting frame is arranged on the side of the mounting base plate, the mounting base plate and the DNA synthesis machine can be conveniently assembled through the supporting frame, safety protection can be achieved, the mounting grooves are formed in the mounting base plate, a plurality of DNA synthesis plate bodies can be conveniently embedded and assembled through the mounting grooves, and mounting and dismounting are convenient; the DNA synthesis plate comprises a DNA synthesis plate main body, four prepared liquid adding ports are formed in the DNA synthesis plate main body, a DNA synthesis groove is formed in the middle of the DNA synthesis plate main body, the prepared liquid adding ports are connected with the DNA synthesis groove through liquid guide pipes, automatic synthesis and continuous supply synthesis of DNA are facilitated through the design, the synthesis efficiency is high, and a synthesis liquid taking-out port is formed in the top of the DNA synthesis groove.

Description

Technical Field

[0001] The utility model relates to the field of DNA synthesis boards, in particular to a DNA synthesis board. Background Art

[0002] DNA synthesis is a traditional and classic method of producing cDNA fragments through RNA extraction, reverse transcription and other processes. But the disadvantage is that the process is long, time-consuming and labor-intensive. Direct gene synthesis is more popular abroad. In fact, the principle is to synthesize long DNA single strands first, which have complementary pairing, and then obtain the complete sequence through PCR amplification. You only need to provide the DNA sequence to get the gene in 1-2 weeks;

[0003] For example, the authorized patent with publication number CN210394317U (DNA synthesis board): The DNA synthesis board includes an assembly tube, and the assembly tube is provided with a plurality of them, each of which is sequentially formed with a first assembly position, a second assembly position and a third assembly position, and the inner diameter of the assembly tube decreases gradually from the first assembly position to the third assembly position; the CPG carrier is assembled in the first assembly position or the second assembly position or the third assembly position of each of the assembly tubes. The technical solution of this utility model is to improve the compatibility of the DNA synthesis board;

[0004] The above-mentioned prior art cannot add post-automatic synthesis control, and cannot perform multiple groups of DNA synthesis at the same time. In addition, the installation and fixation of the synthesis plate is not convenient enough, the synthesis control is not stable enough, the synthesis process is prone to waste, and the DNA synthesis tank cannot be sealed. Utility Model Content

[0005] The utility model aims to provide a DNA synthesis plate to solve the problems proposed in the above-mentioned background technology that automatic synthesis control cannot be added, multiple groups of DNA synthesis cannot be performed simultaneously, the installation and fixation of the synthesis plate is not convenient enough, the synthesis control is not stable enough, the synthesis process is prone to waste, and the DNA synthesis tank cannot be sealed.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a DNA synthesis plate, comprising a mounting pad and a DNA synthesis plate body, a plurality of the DNA synthesis plate bodies are arranged on a mounting groove of the mounting pad by an inlay manner, the DNA synthesis plate body is provided with four liquid addition ports and a DNA synthesis groove, and a support frame is provided on the side of the mounting pad.

[0007] In a further embodiment, a synthesis liquid outlet is provided on the top of the DNA synthesis tank, and a sealing cover that can be opened laterally is provided on the top of the synthesis liquid outlet.

[0008] In a further embodiment, a liquid guiding groove is provided at the bottom of the inner cavity of the liquid preparation inlet, and the liquid preparation inlet is configured as a conical structure.

[0009] In a further embodiment, a wear-resistant base is provided at the bottom of the DNA synthesis board body, and the wear-resistant base is embedded in the mounting groove.

[0010] In a further embodiment, there are four support frames in total, and the four support frames are respectively arranged at four sides of the mounting pad of the square structure.

[0011] In a further embodiment, the mounting pad is used to be embedded in a DNA synthesizer, the DNA synthesis tank is arranged in the middle of the four liquid preparation inlets, and the liquid preparation inlet is connected to the DNA synthesis tank through a liquid guide tube.

[0012] Compared with the prior art, the beneficial effects of the utility model are:

[0013] 1. The utility model is provided with a mounting pad, and a support frame is provided on the side of the mounting pad, which facilitates the assembly of the mounting pad and the DNA synthesizer through the support frame, and can provide safety protection. In addition, a mounting groove is provided on the mounting pad, and the mounting groove facilitates the inlay assembly of multiple DNA synthesis board bodies, which is convenient for installation and disassembly.

[0014] 2. The utility model has four liquid preparation inlets on the main body of the DNA synthesis plate, a DNA synthesis tank is provided in the middle of the main body of the DNA synthesis plate, and the liquid preparation inlet is connected to the DNA synthesis tank through a liquid guide tube. This design facilitates automatic DNA synthesis and continuous synthesis, and the synthesis efficiency is high. A synthesis liquid outlet is provided on the top of the DNA synthesis tank, and a sealing cover is provided on the synthesis liquid outlet, which can avoid the waste of synthesis liquid. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 This is a structural schematic diagram of a DNA synthesis plate of the utility model;

[0016] Figure 2 It is a cross-sectional view of the main body of the DNA synthesis board of the utility model;

[0017] Figure 3 It is a top view of the main body of the DNA synthesis board of the utility model;

[0018] Figure 4 It is a structural schematic diagram of part A of the utility model.

[0019] In the figure: 1. Installation groove; 2. Support frame; 3. Installation pad; 4. DNA synthesis board body; 5. Liquid addition inlet; 6. Wear-resistant base; 7. Liquid guide tube; 8. DNA synthesis groove; 9. Liquid guide groove; 10. Sealing cover; 11. Synthesis liquid removal outlet. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0021] See also Figure 1-4 The utility model provides an embodiment: a DNA synthesis plate, comprising a mounting pad 3 and a DNA synthesis plate body 4, a plurality of DNA synthesis plate bodies 4 are arranged on the mounting groove 1 of the mounting pad 3 by means of an inlay, the DNA synthesis plate body 4 is provided with four liquid preparation inlets 5 and a DNA synthesis groove 8, and a support frame 2 is provided on the side of the mounting pad 3; the mounting pad 3 is convenient for assembly with a DNA synthesizer, the liquid preparation inlet 5 is convenient for simultaneously adding the preparation liquids for synthesis in categories, and can be automatically introduced into the DNA synthesis groove 8 for synthesis, which is convenient to use, can perform automatic synthesis, and is convenient to use. The support frame 2 is used to perform side protection on the mounting pad 3, and a total of four support frames 2 are provided, and the four support frames 2 are respectively arranged at the four sides of the mounting pad 3 of the square structure.

[0022] A synthesis liquid outlet 11 is provided at the top of the DNA synthesis tank 8, and a sealing cover 10 that can be opened laterally is provided at the top of the synthesis liquid outlet 11. The synthesized DNA can be conveniently taken out through the synthesis liquid outlet 11, and the sealing cover 10 can seal the synthesis liquid outlet 11 to prevent leakage and waste.

[0023] A liquid guide groove 9 is provided at the bottom of the inner cavity of the liquid preparation inlet 5, and the liquid preparation inlet 5 is set to a conical structure, and the liquid preparation can be conveniently guided out through the liquid guide groove 9. The mounting pad 3 is used to be embedded in the DNA synthesizer, and the DNA synthesis tank 8 is set in the middle of the four liquid preparation inlets 5, and the liquid preparation inlet 5 is connected to the DNA synthesis tank 8 through a liquid guide tube 7, and the liquid preparation in the liquid preparation inlet 5 is conveniently guided into the DNA synthesis tank 8 through the liquid guide tube 7.

[0024] A wear-resistant base 6 is provided at the bottom of the DNA synthesis board body 4 , and the wear-resistant base 6 is embedded in the installation groove 1 , and the DNA synthesis board body 4 can be installed and protected by the wear-resistant base 6 .

[0025] Working principle: When in use, the support frame 2 is used to protect the side of the installation pad 3 and facilitate the installation and fixation of the installation pad 3. The synthesized preparation liquid is added from the preparation liquid addition port 5, and is guided down through the liquid guide groove 9, and is guided to the DNA synthesis groove 8 through the liquid guide tube 7. Synthesis is carried out in the DNA synthesis groove 8, and the top of the synthesis liquid removal port 11 is sealed by the sealing cover 10. The synthesized DNA liquid can be conveniently taken out through the synthesis liquid removal port 11. The wear-resistant base 6 at the bottom of the DNA synthesis board body 4 is convenient for inlay and assembly with the installation groove 1. The side of the installation pad 3 can be protected by the support frame 2.

[0026] It is obvious to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above, and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be regarded as exemplary and non-restrictive from any point of view, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

Claims

1. A DNA synthesis board, comprising a mounting pad (3) and a DNA synthesis board body (4), characterized in that: A plurality of the DNA synthesis plate bodies (4) are arranged on the mounting groove (1) of the mounting pad (3) by means of an inlay method. The DNA synthesis plate bodies (4) are provided with four liquid addition ports (5) and a DNA synthesis groove (8). A support frame (2) is provided on the side of the mounting pad (3).

2. A DNA synthesis plate according to claim 1, characterized in that: The top of the DNA synthesis tank (8) is provided with a synthesis liquid outlet (11), and the top of the synthesis liquid outlet (11) is provided with a sealing cover (10) that can be opened laterally.

3. A DNA synthesis plate according to claim 1, characterized in that: A liquid guiding groove (9) is provided at the bottom of the inner cavity of the liquid preparation inlet (5), and the liquid preparation inlet (5) is configured as a conical structure.

4. A DNA synthesis plate according to claim 1, characterized in that: A wear-resistant base (6) is provided at the bottom of the DNA synthesis plate body (4), and the wear-resistant base (6) is inlaid with the installation groove (1).

5. A DNA synthesis plate according to claim 1, characterized in that: A total of four support frames (2) are provided, and the four support frames (2) are respectively arranged at four sides of the mounting pad (3) of the square structure.

6. A DNA synthesis plate according to claim 1, characterized in that: The mounting pad (3) is used to be embedded in a DNA synthesizer. The DNA synthesis tank (8) is arranged in the middle of the four liquid preparation inlets (5), and the liquid preparation inlets (5) are connected to the DNA synthesis tank (8) via a liquid guide tube (7).

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