A high-speed mixing granulator for drug production

By introducing a mixing system of water pump and atomizing spray head, a cylinder-controlled discharge mechanism, a cooling system of cooling tank and fan, and a water spray mechanism in the high-speed mixing and granulator, the problem of poor heat generation and cleaning effect during high-speed rotary stirring is solved, and a more efficient drug mixing and discharge process is achieved, ensuring the quality of the drug and the cleanliness of the equipment.

CN222694672UActive Publication Date: 2025-04-01YUNNAN HUANGYADAI PHARM CO LTD
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Patent Information

Application Number
CN202420728612.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-10
Publication Date
2025-04-01
Estimated Expiration
2034-04-10

AI Technical Summary

Technical Problem

The existing high-speed mixed granulator of drug production generates heat during high-speed rotating and stirring, affecting the quality of the drug, and has poor cleaning effect, which poses a risk of blockage of the discharge port.

Method used

A mixing system including a water pump and atomizing spray head is designed to uniformly mix drugs and adhesives, and to control the opening and closing of the discharge barrel through the cylinder, and rotate the propeller blades for quick discharge. At the same time, a cooling tank is set at the bottom of the granulation barrel and cooling is carried out through a fan to ensure the constant temperature. In addition, the atomization nozzle is driven to clean the side wall of the granulation barrel through the water spraying mechanism to improve the cleaning efficiency.

Benefits of technology

It effectively reduces the heat generated during the stirring process, improves the quality of medicines, and ensures smooth discharge and improves cleaning efficiency.

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    Figure CN222694672U_ABST
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Abstract

The utility model discloses a high-speed mixing granulator for drug production, including: a box, a granulation barrel, a locking mechanism, a cutting knife roller, a discharging mechanism, a cooling trough, a fixed cylinder, a propeller blade, a transmission mechanism, and a water spraying mechanism. The upper side of the box is fixedly connected with the granulation barrel, a locking mechanism is arranged between the box cover and the upper part of the granulation barrel, one end of the motor is fixedly connected with the cutting knife roller, the lower end of the outer side of the granulation barrel is provided with a discharging mechanism, the outer side of the fixed box is provided with a propeller blade, the lower part of the fixed cylinder is provided with a transmission mechanism, and the bottom side of the box is provided with a water spraying mechanism. Compared with the prior art, the utility model has the advantages of: a fan is arranged to blow air into the cooling trough to cool the bottom of the granulation barrel, so as to ensure a constant temperature during drug granulation; a water spraying mechanism is arranged to cooperate with a rotating mechanism to perform rotary water spraying cleaning on the granulation barrel wall, thereby improving the cleaning efficiency.
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Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical engineering, in particular to a high-speed mixing granulator for drug production. Background Art

[0002] The high-speed mixing granulator is supported by the machine body, with the pot as the material container, and the stirring rotation and cutting knife transmission as the power. The material is stirred by a stirring paddle, so that the material is rolled and mixed evenly in a short time, and then made into granules by the cutting knife, and finally discharged from the discharge port. By changing the rotation speed of the stirring and cutting knife, the granules of different sizes can be obtained, which plays a great role in the drug production process.

[0003] A high-speed mixing granulator for drug production described in publication number CN219836462U is provided with a discharge assembly at the discharge port of a mixing barrel in the high-speed mixing granulator for drug production, and the discharge of drug particles is controlled by a baffle, and the drug is conveyed by a conveying screw and a discharge pipe, thereby controlling the conveying and discharge of drug particles, and avoiding blockage of the discharge port of the mixing barrel. At the same time, an arc plate and a brush are provided inside the mixing barrel, which can not only assist in the discharge of drug particles, but also clean the inner wall of the mixing barrel. However, the prior art still has defects:

[0004] 1. Since the diameter of the drug particles after granulation and cutting is very small, and the diameter of the discharge barrel is large, there will be no blockage of the discharge port. The advantages of the prior art are not obvious, and a certain amount of heat will be generated due to the influence of friction during high-speed rotation and stirring. The prior art does not have a cooling device, which will affect the quality of the drug to a certain extent.

[0005] 2. The prior art only cleans the barrel wall by arranging an arc plate and a brush inside, but the cleaning effect is not obvious due to the small size of the brush. Utility Model Content

[0006] The technical problem to be solved by the utility model is to solve the above-mentioned problem and provide a high-speed mixing granulator for medicine production.

[0007] In order to solve the above technical problems, the technical solution provided by the utility model is: a high-speed mixing granulator for drug production, including a box body, a granulation barrel is fixedly connected to one side of the upper part of the box body, a box cover is arranged on the upper part of the granulation barrel, a plurality of evenly distributed locking mechanisms are arranged between the box cover and the upper part of the granulation barrel, a feed port is plugged into one side of the upper part of the box cover, a water pump is fixedly connected to the other side of the upper part of the box cover, an atomizing nozzle is arranged at the lower end of the water pump, a lower end of the atomizing nozzle penetrates the box cover and extends to the inside of the granulation barrel, a motor room is fixedly connected to one side of the upper part of the box body, a motor is arranged inside the motor room, and the motor One end penetrates the wall of the granulation barrel and is fixedly connected with a cutting roller, the cutting roller is arranged inside the granulation barrel, a discharging mechanism is arranged at the lower end of one side outside the granulation barrel, a circular cooling groove is opened at the bottom of the granulation barrel, two fans are fixedly connected at the upper part of the box body corresponding to the cooling groove, a fixed cylinder is rotatably connected to the middle of the bottom of the granulation barrel, a circular fixed box is fixedly connected to the upper end of the fixed cylinder, a number of evenly distributed triangular propeller blades are arranged at the bottom of the outer curved wall of the fixed box, a water spray chamber is fixedly connected to the upper part of the fixed box, a transmission mechanism is arranged at the lower part of the fixed cylinder, and a water spray mechanism is arranged at one side of the bottom end inside the box body.

[0008] As an improvement, the locking mechanism includes a connecting seat fixedly connected to the front and rear ends and both sides of the upper outer wall of the granulating barrel, a connecting rod is rotatably connected in the middle of the connecting seat, a clamping head is fixedly connected to the upper end of the connecting rod, and a U-shaped clamping plate is fixedly connected to both sides and the front and rear ends of the upper part of the box cover, and the connecting rod is clamped inside the clamping plate.

[0009] As an improvement, the discharging mechanism includes a discharging barrel inserted into the lower part of one side of the granulation barrel, the discharging barrel is fixedly connected to a cylinder on the side away from the granulation barrel, one end of the cylinder telescopic rod is fixedly connected to a sealing plate, and a discharging pipe is inserted into the lower part of the discharging barrel.

[0010] As an improvement, the transmission mechanism includes gear 1 which is sleeved on the lower end of the fixed cylinder, gear 1 is meshed with gear 2 on one side, motor 2 is fixedly connected to one side of gear 2, the lower end of motor 2 is fixedly connected to an L-shaped support frame, and the upper end of the support frame is fixedly connected to the upper end of the box.

[0011] As an improvement, the water spray mechanism includes two atomizing nozzles plugged into both sides of the water spray chamber, two water pumps are arranged inside the fixed box, the lower end of the two water pumps is connected to the interior of the fixed cylinder, a sealed bearing is fixedly connected to the lower end of the interior of the fixed cylinder, a water inlet pipe is plugged into the interior of the sealed bearing, a water tank is fixedly connected to one side of the bottom of the box body, and the lower end of the water inlet pipe extends to the interior of the water tank.

[0012] Compared with the prior art, the utility model has the following advantages: 1. The utility model is connected to an atomizing nozzle through a water pump on a box cover; the water pump is externally connected to a water pipe for extracting adhesive and spraying it out through an atomizing nozzle, so that the adhesive and the drug dry material are more evenly mixed; a discharging mechanism is provided to drive a sealing plate through a cylinder to seal or open a discharging barrel, and the propeller blades rotate to make the discharging more convenient and quick; a circular cooling groove is provided at the bottom of the granulating barrel, and two fans are provided at the upper part of the box body corresponding to the cooling groove; the fans blow air upward so that the air in the cooling groove flows to cool the bottom of the granulating barrel, thereby reducing the heat generated by the stirring friction of the propeller blades driven by the fixed barrel, and ensuring a constant temperature during drug granulation.

[0013] 2. The utility model provides a fixed box at the upper end of the fixed cylinder, a water spray chamber is provided at the upper end of the fixed box, two atomizing nozzles are provided on both sides of the water spray chamber, two water pumps are provided in the fixed box, and the upper and lower ends of the water pumps are connected with the water spray chamber and the fixed cylinder respectively, the lower end of the fixed cylinder is connected with the water inlet pipe through a sealed bearing, the lower end of the water inlet pipe is provided in the water tank, the fixed cylinder is driven to rotate through a transmission mechanism, thereby controlling the rotation of the two atomizing nozzles, the two water pumps pump clean water into the water spray chamber, and the water is sprayed out by the two atomizing nozzles to clean the side wall of the granulating barrel, thereby improving the cleaning efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 The utility model is a three-dimensional schematic diagram of a high-speed mixing granulator for medicine production.

[0015] Figure 2 It is a partial structural stereogram of a high-speed mixing granulator for medicine production of the utility model.

[0016] Figure 3 The utility model is a schematic diagram of a main cross-section of a high-speed mixing granulator for drug production.

[0017] Figure 4 The utility model is a stereoscopic diagram of a card plate of a high-speed mixing granulator for medicine production.

[0018] Figure 5 It is an enlarged view of A of a high-speed mixing granulator for drug production of the utility model.

[0019] As shown in the figure: 1. Box body; 2. Granulating barrel; 3. Box cover; 4. Locking mechanism; 4.1. Connecting seat; 4.2. Connecting rod; 4.3. Clamp; 4.4. Clamp; 5. Feed inlet; 6. Water pump 1; 7. Atomizing nozzle 1; 8. Motor room; 9. Motor 1; 10. Cutting knife roller; 11. Discharging mechanism; 11.1. Discharging barrel; 11.2. Cylinder; 11.3. Sealing plate; 11.4. Discharging pipe; 12. Cooling trough; 13. Fan; 14. Fixed cylinder; 15. Fixed box; 16. Propeller blades; 17. Water spray chamber; 18. Transmission mechanism; 18.1. Gear 1; 18.2. Gear 2; 18.3. Motor 2; 18.4. Support frame; 19. Water spray mechanism; 19.1. Atomizing nozzle 2; 19.2. Water pump 2; 19.3. Sealed bearing; 19.4. Water inlet pipe; 19.5. Water tank. DETAILED DESCRIPTION

[0020] The utility model is further described in detail below in conjunction with the accompanying drawings.

[0021] Combined with Figure 1 A box body 1 is provided, which is a steel box body with legs provided at the bottom for support, and a ventilation hole is provided on one side for ventilation and heat dissipation. A granulating barrel 2 is fixedly connected to one side of the upper part of the box body 1, and a box cover 3 is provided on the upper part of the granulating barrel 2. A plurality of evenly distributed locking mechanisms 4 are provided between the box cover 3 and the upper part of the granulating barrel 2, including a connecting seat 4.1 fixedly connected to the front and rear ends and both sides of the upper part of the outer wall of the granulating barrel 2, a connecting rod 4.2 is rotatably connected in the middle of the connecting seat 4.1, and a clamping head 4.3 is fixedly connected to the upper end of the connecting rod 4.2, and a U-shaped clamping plate 4.4 is fixedly connected to the upper part of the box cover 3 corresponding to the connecting seat 4.1, and the connecting rod 4.2 is clamped in the U-shaped groove by rotating the connecting rod 4.2, and the clamping head 4.3 is clamped at the upper end of the clamping plate 4.4 to fix the box cover 3. When it needs to be opened, it only needs to push the clamping head 4.3 to rotate the connecting rod 4.2 to disengage the clamping plate 4.4.

[0022] A fixed cylinder 14 is rotatably connected to the middle of the bottom of the granulating barrel 2, and a circular fixed box 15 is fixedly connected to the upper end of the fixed cylinder 14. Three triangular propeller blades 16 are evenly distributed at the bottom of the outer curved wall of the fixed box 15, and are arranged in an inclined manner. When rotating, the powder can be driven to be thrown upward and hit the wall of the granulating barrel 2 to make the dry powder mixing more uniform and compact. A transmission mechanism 18 is arranged at the lower part of the fixed cylinder 14, including a gear 18.1 sleeved on the lower end of the fixed cylinder 14, and a gear 2 18.2 is meshed on one side of the gear 18.1. Both the gear 18.1 and the gear 2 18.2 are bevel gears, and a motor 2 18.3 is fixedly connected to one side of the gear 2 18.2. An L-shaped support frame 18.4 is arranged on the upper end of the box body 1 to fix the motor 2 18.3. The motor 2 18.3 rotates the gear 2 18.2 to drive the fixed cylinder 14 to rotate, and the drug dry powder is stirred and mixed.

[0023] A feed port 5 is inserted on one side of the upper part of the box cover 3 for feeding dry drug powder. A water pump 6 is fixedly connected to one side of the upper part of the box cover 3. An atomizing nozzle 7 is provided at the lower end of the water pump 6 and is arranged inside the granulation barrel 2. An external water pipe is connected to the upper end of the water pump 6 to extract the adhesive and spray it into the granulation barrel 2 through the atomizing nozzle 7, thereby increasing the spraying range of the adhesive and making the adhesive and the dry drug powder combine more evenly.

[0024] A motor room 8 is fixedly connected to one side of the upper part of the box body 1, and a motor 9 is arranged inside the motor room 8. The output end of the motor 9 passes through the wall of the granulation barrel 2 and is fixedly connected to a cutting roller 10. A plurality of steel blades are arranged on the outside of the cutting roller 10. The cutting roller 10 is driven by the motor 9 to rotate to cut and break the bonded drugs into small particles.

[0025] A discharging mechanism 11 is arranged at the lower end of one side of the outside of the granulating barrel 2, including a discharging barrel 11.1 plugged into the lower part of one side of the granulating barrel 2, and a cylinder 11.2 is fixedly connected to the side of the discharging barrel 11.1 away from the granulating barrel 2, and a sealing plate 11.3 is fixedly connected to one end of the telescopic rod of the cylinder 11.2. The sealing plate 11.3 is a circular steel plate, the size of which is the same as the inner diameter of the discharging barrel 11.1 and a rubber sealing gasket is arranged on the outer ring, which is used to seal the opening of the side wall of the granulating barrel 2, and a discharging pipe 11.4 is plugged into the lower part of the discharging barrel 11.1 for discharging. After granulation is completed, the sealing plate 11.3 is retracted by the cylinder 11.2 to open the discharging port, and the propeller blades 16 scrape the granules outwards in conjunction with the low-speed rotation of the motor 18.3, and the granules are discharged from the discharging pipe 11.4.

[0026] A circular cooling groove 12 is provided at the bottom of the granulating barrel 2, and two fans 13 are fixedly connected to the upper part of the box body 1 corresponding to the cooling groove 12. The fans 13 blow air upward to drive the air inside the cooling groove 12 to continuously flow and dissipate the heat generated by stirring friction.

[0027] A water spray chamber 17 is fixedly connected to the upper part of the fixed box 15. The upper end of the water spray chamber 17 is conical, and a space is provided inside. Two atomizing nozzles 19.1 of the water spray mechanism 19 are plugged on both sides. A water pump 19.2 is arranged inside the fixed box 15. The upper end of the water pump 19.2 is communicated with the inside of the water spray chamber 17, and the lower end is connected to the inside of the fixed cylinder 14. A sealed bearing 19.3 is fixedly connected to the lower end of the fixed cylinder 14. A water inlet pipe 19.4 is plugged inside the sealed bearing 19.3. As the fixed cylinder 14 rotates, the water inlet pipe 19.4 remains stationary. A water tank 19.5 is fixedly connected to one side of the bottom of the box body 1 for holding clean water. The lower end of the water inlet pipe 19.4 extends to the inside of the water tank 19.5. Clean water is pumped into the water spray chamber 17 through the water pump 19.2 and sprayed through both sides of the atomizing nozzle 19.1. At the same time, the transmission mechanism 18 drives the fixed cylinder 14 to rotate to clean the side wall of the granulating barrel 2.

[0028] When the utility model is implemented, Figure 1 As shown, the prize box cover 3 is covered on the upper part of the granulation barrel 2 and locked by the locking mechanism 4, the powder is put into the granulation barrel 2 through the feed port 5, the motor 18.3 is started to drive the fixed cylinder 14 and the fixed box 15 to rotate through the transmission mechanism 18, so as to control the rotation of the propeller blade 16 to stir and mix the powder, the water pump 16 is connected to the external water pipe, and the adhesive is extracted and sprayed through the atomizing nozzle 7 below, so that the adhesive and the powder are evenly mixed, and the stirring of the propeller blade 16 makes the powder become a soft material. Start the motor 19 to drive the cutting roller 10 to rotate and cut and break the soft powder and soft material being stirred, so that the particles collide more evenly and finely, and finally form stable spherical particles. The bottom of the granulation barrel 2 is cooled by blowing air in the cooling tank 12 through the fan 13 on the upper part of the box body 1 to keep the internal temperature constant. After the granulation is completed, the cylinder 11.2 is started to discharge through the discharging mechanism 11, and the water pump 19.2 is started to rotate the water spray mechanism 19 to cooperate with the fixed cylinder 14 to rotate and spray water to clean the inner side wall of the granulation barrel 2.

[0029] The above description of the utility model and its implementation methods is not restrictive. The drawings show only one implementation method of the utility model, and the actual structure is not limited thereto. In short, if ordinary technicians in this field are inspired by it and design structural methods and embodiments similar to the technical solution without creativity without departing from the purpose of the invention of the utility model, they should all fall within the protection scope of the utility model.

Claims

1. A high-speed mixing granulator for drug production, comprising a housing (1), characterized in that: A granulating barrel (2) is fixedly connected to one side of the upper part of the box body (1), a box cover (3) is arranged on the upper part of the granulating barrel (2), a plurality of evenly distributed locking mechanisms (4) are arranged between the box cover (3) and the upper part of the granulating barrel (2), a feed port (5) is inserted into one side of the upper part of the box cover (3), a water pump (6) is fixedly connected to the other side of the upper part of the box cover (3), an atomizing nozzle (7) is arranged at the lower end of the water pump (6), the lower end of the atomizing nozzle (7) passes through the box cover (3) and extends into the interior of the granulating barrel (2), a motor room (8) is fixedly connected to one side of the upper part of the box body (1), a motor (9) is arranged inside the motor room (8), one end of the motor (9) passes through the wall of the granulating barrel (2) and is fixedly connected to a cutting knife roller (10), the cutting knife roller (10) is arranged inside the granulating barrel (2), a discharging mechanism (11) is arranged at the lower end of one side of the outside of the granulating barrel (2), a circular cooling groove (12) is opened at the bottom of the granulating barrel (2), two fans (13) are fixedly connected to the upper part of the box body (1) corresponding to the cooling groove (12), a fixed cylinder (14) is rotatably connected to the middle of the bottom of the granulating barrel (2), a circular fixed box (15) is fixedly connected to the upper end of the fixed cylinder (14), a plurality of evenly distributed triangular propeller blades (16) are arranged at the bottom of the outer curved wall of the fixed box (15), a water spray chamber (17) is fixedly connected to the upper part of the fixed box (15), a transmission mechanism (18) is arranged at the lower part of the fixed cylinder (14), and a water spray mechanism (19) is arranged at one side of the bottom end of the box body (1).

2. A high-speed mixing granulator for drug production according to claim 1, characterized in that: The locking mechanism (4) comprises a connecting seat (4.1) fixedly connected to the front and rear ends and both sides of the upper outer wall of the granulating barrel (2); a connecting rod (4.2) is rotatably connected in the middle of the connecting seat (4.1); a clamping head (4.3) is fixedly connected to the upper end of the connecting rod (4.2); a U-shaped clamping plate (4.4) is fixedly connected to both sides and the front and rear ends of the upper part of the box cover (3); and the connecting rod (4.2) is clamped inside the clamping plate (4.4).

3. A high-speed mixing granulator for drug production according to claim 1, characterized in that: The discharging mechanism (11) comprises a discharging barrel (11.1) plugged into the lower part of one side of the granulating barrel (2); a cylinder (11.2) is fixedly connected to the side of the discharging barrel (11.1) away from the granulating barrel (2); a sealing plate (11.3) is fixedly connected to one end of the telescopic rod of the cylinder (11.2); and a discharging pipe (11.4) is plugged into the lower part of the discharging barrel (11.1).

4. A high-speed mixing granulator for drug production according to claim 1, characterized in that: The transmission mechanism (18) comprises a gear 1 (18.1) sleeved on the lower end of the fixed cylinder (14); one side of the gear 1 (18.1) is meshed with a gear 2 (18.2); one side of the gear 2 (18.2) is fixedly connected to a motor 2 (18.3); the lower end of the motor 2 (18.3) is fixedly connected to an L-shaped support frame (18.4); the upper end of the support frame (18.4) is fixedly connected to the upper end of the box body (1).

5. A high-speed mixing granulator for drug production according to claim 1, characterized in that: The water spray mechanism (19) comprises two atomizing nozzles (19.1) plugged into two sides of the water spray chamber (17); a water pump (19.2) is arranged inside the fixed box (15); the lower end of the water pump (19.2) is connected to the inside of the fixed cylinder (14); a sealing bearing (19.3) is fixedly connected to the lower end of the fixed cylinder (14); a water inlet pipe (19.4) is plugged into the inside of the sealing bearing (19.3); a water tank (19.5) is fixedly connected to one side of the bottom of the box body (1); and the lower end of the water inlet pipe (19.4) extends to the inside of the water tank (19.5).

Citation Information

Patent Citations

  • High-speed mixing granulator for medicine production

    CN219836462U