A fully automatic high-precision laboratory liquid dispenser

Abstract

The utility model discloses a fully automatic high-precision laboratory liquid dispenser, which relates to the field of automation technology. The fully automatic high-precision laboratory liquid dispenser includes a high-precision liquid dispensing device for performing the aspiration and precise distribution of liquid samples; an automatic control device connected to the high-precision liquid dispensing device for controlling the action of the liquid dispensing device according to preset parameters; and a human-computer interaction device connected to the automatic control device for controlling the automatic control device and displaying the device status according to the liquid dispensing parameters input by the user. The above realizes a fully automatic and high-precision liquid dispensing operation.

Description

Technical Field

[0001] The utility model relates to the technical field of automation, in particular to a fully automatic high-precision laboratory liquid dispenser. Background Art

[0002] With the rapid development of life science research such as biology, medicine, and pharmacy, the demand for laboratory analysis and testing is increasing, requiring dispensing technology that can accurately dispense trace amounts of liquid samples.

[0003] At present, laboratory liquid separation operations mainly rely on manual operation or semi-automatic equipment. In the scenario of using semi-automatic equipment for liquid separation, the experimenter first manually draws a certain amount of solution from the original sample with a pipette. Fix the pipette on the holder of the semi-automatic pipette, align the pipette with the first tube sample through the turntable, set the angle of the turntable rotation and the depth parameters of the pipette pressing, start the semi-automatic pipette, it will automatically rotate the turntable, press the pipette, and move a certain amount of sample into the first tube. The experimenter then manually moves the pipette to the second tube sample, repeats steps 3-4, completes the pipetting, and repeats the operation until the inoculation of multiple samples is completed. Finally, the experimenter manually removes the pipette and puts it in the washing tank for cleaning.

[0004] Traditional laboratory liquid dispensing equipment usually adopts a simple automatic control method, which is complicated to operate and has low liquid dispensing accuracy. It still requires a certain amount of manual participation, making it difficult to achieve fully automatic and high-precision liquid dispensing operations. Utility Model Content

[0005] In order to solve the problems and shortcomings of the above-mentioned prior art, the purpose of the utility model is to provide a fully automatic high-precision laboratory liquid dispenser, which is used to realize fully automatic and high-precision liquid dispense operation under the circumstances where the liquid dispense method in the prior art is complicated to operate and has low liquid dispense accuracy and requires certain manual participation.

[0006] To achieve the above-mentioned purpose, in the first aspect, the present application provides a fully automatic high-precision laboratory dispenser, the system comprising: a high-precision liquid dispensing device, used to perform the aspiration and precise distribution of liquid samples; an automatic control device, connected to the high-precision liquid dispensing device, used to control the action of the liquid dispensing device according to preset parameters; a human-computer interaction device, connected to the automatic control device, used to control the automatic control device and display the device status according to the liquid dispensing parameters input by the user.

[0007] In the above embodiment, the fully automatic high-precision laboratory liquid dispenser achieves accurate aspiration and distribution of liquid samples by integrating a high-precision liquid dispensing device and an automatic control device. This automated operation not only significantly improves the experimental efficiency, but also ensures the repeatability and accuracy of the experimental results. The addition of a human-computer interaction device allows the operator to easily set the liquid dispensing parameters and monitor the device status in real time, thereby reducing the complexity of the operation and improving the user experience.

[0008] In combination with some embodiments of the first aspect, in some embodiments, a cleaning device is further included, which is associated with the automatic control device, and includes a cleaning liquid storage tank for storing cleaning liquid; a cleaning pump for extracting the cleaning liquid; a cleaning nozzle for spraying the cleaning liquid; and a cleaning control module for controlling the extraction and spraying process of the cleaning pump to achieve automatic cleaning of the convection path.

[0009] In the above embodiment, by introducing the cleaning device, the liquid dispenser can automatically clean after each liquid dispensing operation, effectively avoiding the problem of cross contamination. The cleaning device includes a cleaning liquid storage tank for storing cleaning liquid, a cleaning pump and a cleaning nozzle, and these components work together to ensure thorough cleaning of the entire flow channel.

[0010] In combination with some embodiments of the first aspect, in some embodiments, a quantitative liquid aspiration device is further included, which is associated with the automatic control device, and the quantitative liquid aspiration device includes a liquid aspiration pump with a set volume, which is used to aspirate the set volume of liquid with high precision; a liquid level sensor, which monitors and feeds back liquid aspiration volume data in real time; and a liquid aspiration control module, which is connected to the liquid aspiration pump and the liquid level sensor, and is used to control the operation of the liquid aspiration pump according to the set volume, and to achieve closed-loop control according to the liquid aspiration volume data.

[0011] In the above embodiment, the quantitative liquid aspiration device achieves the absorption of the precise volume of the liquid sample by accurately controlling the liquid aspiration pump and cooperating with the feedback of the liquid level sensor. This high-precision control technology not only improves the accuracy of the operation, but also ensures the consistency of the amount of liquid aspiration each time through a closed-loop control system, greatly enhancing the repeatability and reliability of the experiment.

[0012] In combination with some embodiments of the first aspect, in some embodiments, a dispensing device is further included, which is associated with the automatic control device, and includes a pipetting arm for movably connecting a liquid transmission pipeline; a dispensing port, which is arranged at the end of the pipetting arm, for dispensing liquid; a positioning module, which is used to control the movement and positioning of the pipetting arm in three-dimensional space; and a dispensing control module, which controls the movement of the pipetting arm according to the target container position to achieve liquid distribution.

[0013] In the above embodiment, the design of the dispensing device allows the pipetting arm to move and position accurately in three-dimensional space, which is particularly important for the liquid distribution of multiple containers in the experiment. The precise control of the positioning module ensures that the liquid can be accurately distributed to the target container, regardless of the size or position of the container. In addition, the optimization of the distribution control module further improves the distribution efficiency and accuracy, especially showing its high efficiency when processing a large number of samples.

[0014] In combination with some embodiments of the first aspect, in some embodiments, the dispensing device also includes a liquid detection unit, which is arranged at the dispensing port and is used to detect liquid parameters during the dispensing process, and the liquid parameters include the volume or flow rate of the distributed liquid. The dispensing control module is also used to adjust the dispensing process according to the detection results of the liquid parameters.

[0015] In the above embodiment, the addition of the liquid detection unit enables real-time monitoring of liquid parameters such as volume and flow rate during the liquid dispensing process. This real-time monitoring function makes the dispensing process more accurate, and basically any deviation can be adjusted immediately, ensuring the accuracy of the experimental data and the stability of the experimental process.

[0016] In combination with some embodiments of the first aspect, in some embodiments, the positioning module includes a lateral moving component, a longitudinal moving component and an up and down moving component, and the linked movement of the lateral moving component, the longitudinal moving component and the up and down moving component controls the three-dimensional spatial positioning of the pipetting arm.

[0017] In the above embodiment, the implementation of this three-dimensional positioning system allows the pipetting arm to operate efficiently in a complex working environment, such as transferring liquid between multiple containers at different heights and positions. In addition, the linkage movement mechanism ensures the smoothness and accuracy of the movement, reduces the errors that may occur during the operation, and improves the repeatability and reliability of the experiment.

[0018] In combination with some embodiments of the first aspect, in some embodiments, an image recognition module is further included, which is connected to the automatic control device and is used to perform image recognition on containers in the working area to obtain the position and quantity information of the containers. The automatic control device adjusts the movement trajectory of the pipetting arm according to the image recognition results.

[0019] In the above embodiment, the module identifies the position and number of containers in the working area, so that the automatic control device can adjust the movement trajectory of the pipetting arm according to the real-time image data.

[0020] In combination with some embodiments of the first aspect, in some embodiments, the image recognition module is also used to capture the image of the container to obtain a container image, determine the container type and the liquid level height based on the container image, and feed back the determination result to the automatic control device so that the automatic control device controls the liquid distribution according to the container type and the liquid level height.

[0021] In the above embodiment, the image recognition module can capture the image of the container to determine the type of container and the level of liquid. This function allows the automatic control device to adjust the liquid distribution strategy according to the container type and liquid level, thereby achieving more accurate liquid processing.

[0022] In combination with some embodiments of the first aspect, in some embodiments, the human-computer interaction device includes a display screen and a voice playback module, the display screen is used to display an interactive menu and view the current liquid dispensing status, and the voice playback module is used to play liquid dispensing completion information.

[0023] In the above embodiment, the display screen provides a user interface that displays an interactive menu and real-time dispensing status, allowing the operator to monitor and adjust the dispensing process in real time. The voice playback module automatically plays notification information after the dispensing task is completed, which not only improves work efficiency but also helps the operator manage workload in a multi-tasking environment. Through the dual feedback of vision and hearing, the accuracy of the operation and the convenience of the operator are ensured, especially in a laboratory environment with high load or high precision requirements.

[0024] In combination with some embodiments of the first aspect, in some embodiments, a pneumatic transmission distribution module is also included, which is associated with the automatic control device, and the pneumatic transmission distribution module includes a pneumatic actuator and a pneumatic control unit, and the output end of the pneumatic actuator is connected to the distribution needle; an air source providing unit is used to provide compressed air; the pneumatic control unit is used to control the air source providing unit to provide compressed air to the pneumatic actuator, driving the pneumatic actuator to drive the distribution needle to move to achieve liquid distribution.

[0025] In the above embodiment, the pneumatic actuator receives compressed air through the air source supply unit to drive the dispensing needle to move precisely, thereby achieving precise liquid dispensing. The design of the pneumatic control unit ensures stable output of the air source and precise control of the actuator action, which is crucial to avoid errors and leakage during the liquid dispensing process.

[0026] A fully automatic high-precision laboratory liquid dispenser provided in the embodiments of the present application has at least the following technical effects or advantages:

[0027] 1. Due to the use of high-precision liquid dispensing devices, automatic control devices and human-computer interaction devices, fully automated, high-precision suction and distribution of liquid samples are achieved, which effectively solves the problems of complex liquid dispensing operations, difficult precision control, and the need for a large amount of manual participation in the prior art, thereby achieving fully automated, high-precision controlled liquid dispensing operations.

[0028] 2. The use of a set-volume suction pump, a liquid level sensor, and a closed-loop control module enables accurate setting and monitoring of the liquid volume, thereby effectively solving the problem of the inability to accurately set and control the amount of liquid suction in the prior art, thereby achieving high-precision, high-repeatability quantitative suction.

[0029] 3. Due to the use of the image recognition module, automatic recognition of the position and quantity of containers, as well as judgment of the container type and liquid level are realized, thus effectively solving the problems of incomplete container information recognition and inflexible movement control in the prior art, and then realizing intelligent adjustment of the motion trajectory of the pipetting arm according to the container situation, and flexible and convenient liquid distribution. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 It is a module connection diagram of an embodiment of the utility model;

[0031] Figure 2 It is another module connection diagram of an embodiment of the utility model.

[0032] Description of reference numerals:

[0033] 1. High-precision liquid dispensing device; 2. Automatic control device; 3. Human-computer interaction device; 4. Cleaning device; 5. Quantitative liquid aspiration device; 6. Distribution device; 7. Liquid detection unit; 8. Positioning module; 9. Image recognition module; 10. Display screen; 11. Voice playback module; 12. Pneumatic transmission distribution module. DETAILED DESCRIPTION

[0034] The terms used in the following embodiments of the present application are only for the purpose of describing specific embodiments, and are not intended to be used as limitations to the present application. As used in the specification and appended claims of the present application, the singular expressions "one", "a kind of", "said", "above", "the" and "this" are intended to also include plural expressions, unless there is a clear indication to the contrary in the context. It should also be understood that the term "and / or" used in the present application refers to any or all possible combinations comprising one or more listed items.

[0035] In the following, the terms "first" and "second" are used for descriptive purposes only and are not to be understood as suggesting or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features, and in the description of the embodiments of the present application, unless otherwise specified, "plurality" means two or more.

[0036] In order to make the purpose, technical solution and advantages of the utility model more clear, the utility model is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the utility model and are not used to limit the utility model.

[0037] The utility model embodiment provides a fully automatic high-precision laboratory liquid dispenser, such as Figure 1 As shown, Figure 1 It is a module connection diagram of an embodiment of the utility model, including:

[0038] A high-precision liquid dispensing device 1, used for performing aspiration and precise dispensing of liquid samples;

[0039] An automatic control device 2, connected to the high-precision liquid separation device 1, and used to control the action of the liquid separation device according to preset parameters;

[0040] The human-machine interaction device 3 is connected to the automatic control device 2 and is used to control the automatic control device 2 and display the device status according to the liquid dispensing parameters input by the user.

[0041] Specifically, the high-precision liquid dispensing device 1 is the core part of the fully automatic high-precision laboratory liquid dispensing instrument, which is mainly responsible for the absorption and precise distribution of liquid samples. The device adopts advanced technology and precise mechanical structure, and can control the movement and distribution of liquid very accurately at the micro level. The automatic control device 2 is a key part connected to the high-precision liquid dispensing device 1, and its main function is to control the action of the liquid dispensing device according to preset parameters. This device can include a set of complex software and hardware systems, which can receive the parameters set by the user and automatically adjust the operation of the liquid dispensing device according to these parameters. The human-computer interaction device 3 is another important part connected to the automatic control device 2, and its main function is to provide a user-friendly interface so that the operator can easily input the liquid dispensing parameters and monitor the operating status of the device. This interactive device usually includes input and output devices such as a touch screen, a button, and a display screen 10. Through the human-computer interaction device 3, the user can easily set the parameters such as the liquid aspiration amount, the liquid dispensing speed, and the position of the target container, and can view the working status of the device, alarm information and other important information in real time. This not only greatly reduces the workload of the operator, but also improves the efficiency and safety of the experiment.

[0042] In this way, the fully automatic high-precision laboratory dispenser can automatically complete complex liquid dispensing tasks without human intervention. For example, in a biochemical experiment, the user only needs to enter the required reagent volume and the location of the reaction container on the human-machine interaction device 3, and the rest of the work - including the absorption, transfer and precise distribution of the reagents - is automatically completed by the machine. Through its high-precision liquid dispensing device 1, sophisticated automatic control system and humanized human-machine interaction interface, it provides an efficient, accurate and user-friendly liquid handling solution for the laboratory. This not only greatly improves the efficiency and accuracy of the experiment, but also reduces human errors during the experiment.

[0043] For ease of understanding, the following further describes the modules of the liquid dispenser provided in this embodiment in combination with the above embodiments. Figure 2 , Figure 2 It is another module connection diagram of an embodiment of the utility model.

[0044] exist Figure 2In the invention, the fully automatic high-precision laboratory liquid dispenser includes a cleaning device 4, which is associated with the automatic control device 2. The cleaning device 4 includes a cleaning liquid storage box for storing cleaning liquid; a cleaning pump for extracting the cleaning liquid; a cleaning nozzle for spraying the cleaning liquid; and a cleaning control module for controlling the extraction and spraying process of the cleaning pump to achieve automatic cleaning of the convection path. Specifically, the cleaning device 4 is mainly responsible for thoroughly cleaning the flow path system of the liquid dispenser to remove residual test samples and possible contaminants. The cleaning liquid storage box is used to store special cleaning liquids that can effectively remove biological samples, chemical reagents or any viscous substances. The cleaning pump is responsible for extracting cleaning liquid from the cleaning liquid storage box and pushing the cleaning liquid through the entire flow path system. The cleaning nozzle is installed at a key position of the system to spray cleaning liquid to ensure that all internal surfaces can be cleaned. The core control unit of the cleaning control module is responsible for coordinating the start and stop of the cleaning pump and the spraying action of the nozzle to achieve automatic cleaning. For example, suppose that in a research laboratory, researchers are using a fully automatic high-precision laboratory dispenser to conduct a series of drug screening experiments. These experiments involve a variety of different chemical reagents, and cross-contamination must be avoided between each reagent. After completing the dispensing operation of a set of reagents, the experimenter selects to start the cleaning program through the touch screen interface. The cleaning program first pre-rinses the system with ordinary clean water to remove most of the chemical reagent residues. Subsequently, a special cleaning agent is pumped into the system to deeply clean the inner wall of the pipeline, especially for some reagent residues with high viscosity or strong reactivity. After completing the chemical cleaning, the system is rinsed again to ensure that all cleaning agents are completely removed, and finally compressed air is used for drying to ensure that there are no water droplets remaining inside the pipeline to avoid any possibility of biological contamination. In addition, the automatic detection function of the system can monitor the cleaning status in real time. If the flow and pressure are abnormal, an alarm will be triggered immediately, and a warning message will be displayed on the human-machine interface to prompt the operator to check or repeat the cleaning process to ensure the accuracy and reliability of each experiment.

[0045] This can effectively prevent cross contamination, maintain equipment performance, and improve the accuracy of the experiment.

[0046] In some embodiments, the fully automatic high-precision laboratory dispenser also includes a quantitative liquid imbibition device 5, which is associated with the automatic control device 2, and the quantitative liquid imbibition device 5 includes a liquid imbibition pump with a set volume, which is used to absorb the set volume of liquid with high precision; a liquid level sensor, which monitors and feeds back the liquid absorption amount data in real time; and a liquid imbibition control module, which connects the liquid imbibition pump and the liquid level sensor, and is used to control the operation of the liquid imbibition pump according to the set volume, and realizes closed-loop control according to the liquid absorption amount data. Specifically, the liquid imbibition pump is a precisely controlled pump that can absorb liquid according to a preset volume. The pump is designed to be able to handle liquids of various viscosities, from water samples to viscous biological samples. The liquid level sensor is used to monitor the level of the liquid in the container in real time to ensure that the volume absorbed is accurate. The data of the sensor is directly fed back to the liquid imbibition control module for adjusting the liquid imbibition process. The liquid imbibition control module connects the liquid imbibition pump and the liquid level sensor, controls the operation of the liquid imbibition pump according to the preset volume, and performs closed-loop control according to the real-time data to ensure that each imbibition is extremely accurate. For example, the suction pump is initially started and the liquid is slowly sucked. This stage is mainly to ensure that the air in the suction line is cleared and the liquid can enter the system smoothly. Once the liquid level sensor detects that the liquid has reached a certain height, it will feedback data to the suction control module. The control module adjusts the speed and suction of the suction pump based on the feedback, and accurately controls the amount of liquid sucked to the preset volume. After reaching the preset volume, the liquid level sensor confirms the liquid level again to ensure the accuracy of the suction volume. If necessary, the suction pump will be fine-tuned to ensure the absolute accuracy of the volume. Through such an automated process, not only the work efficiency is improved, but also the accuracy and consistency of the experimental results are ensured.

[0047] In some embodiments, the fully automatic high-precision laboratory dispenser also includes a distribution device 6, which is associated with the automatic control device 2, and the distribution device 6 includes a pipetting arm for movably connecting a liquid transmission pipeline; a distribution port, which is arranged at the end of the pipetting arm, for distributing liquid; a positioning module 8, which is used to control the movement and positioning of the pipetting arm in three-dimensional space; and a distribution control module, which controls the movement of the pipetting arm according to the position of the target container to achieve the distribution of the liquid. Specifically, the positioning module 8 is an actuator for realizing the precise movement of the pipetting arm in three-dimensional space, mainly including a lateral movement component, a longitudinal movement component and an up and down movement component. These three components use a precision stepping motor and a lead screw mechanism, and high-precision movement control can be achieved through computer digital control. The components in the three directions cooperate to move, and the spatial position of the pipetting arm can be flexibly controlled. For example, if the liquid storage container is 100mm behind the left side of the workbench and has a height of 50mm, and the target container is 300mm in front and has a height of 20mm, then the positioning module 8 first controls the pipetting arm to move to a suitable height in the up and down directions, and then moves to the correct position in the horizontal and longitudinal directions. The distribution control module determines the precise coordinates of the target container in combination with the image recognition results, and then plans the optimal spatial motion trajectory of the pipetting arm from the current position to the target position. The motion trajectory calculation should comprehensively consider factors such as motion time, motion range, obstacle avoidance, etc., and output a control signal to guide the positioning module 8 to complete the trajectory movement. For example, a parabolic trajectory that bypasses obstacles can be planned first, so that the pipetting arm can move quickly and smoothly to the target position. After receiving the control signal output by the distribution control module, the positioning module 8 drives the horizontal, vertical, and upper and lower components to move, and accurately controls the pipetting arm to reach the correct position above the target container according to the calculated trajectory. For example, the stepper motor of the component will obtain precise instructions such as "advance 20mm, move left 10mm, and drop 5mm" to control the accurate positioning of the pipetting arm. When the pipetting arm is positioned, the distribution control module calculates and controls the pipetting arm to descend according to the parameters of the target container until the distribution port enters the appropriate depth in the container. Then, the electronically controlled valve at the distribution port is controlled to open, and the liquid sample in the liquid storage container is accurately distributed to the target container using principles such as pressure or liquid surface tension. For example, for trace samples, the dispensing port can be lowered to the liquid surface to dispense liquid with high precision at the milliliter level. This can achieve high-precision liquid sample dispensing function, which is one of the core components of the fully automatic liquid dispensing system and is crucial to ensuring liquid dispensing accuracy.

[0048] In some embodiments, the dispensing device 6 in the fully automatic high-precision laboratory dispenser also includes a liquid detection unit 7, which is arranged at the dispensing port and is used to detect liquid parameters in the dispensing process, and the liquid parameters include the volume or flow rate of the distributed liquid. The distribution control module is also used to adjust the distribution process according to the detection results of the liquid parameters. Specifically, when the volume type liquid detection unit 7 is set, it contains a precise electronic balance inside, which can detect the weight change of the distributed liquid in real time and calculate the volume by weight. When the flow rate type liquid detection unit 7 is set, it contains a flow rate sensor inside, which can detect the rate of liquid flowing out of the distribution port in real time. The detection result of the liquid detection unit 7 will be fed back to the distribution control module in real time. The distribution control module includes a preset distribution volume value or flow rate value. The distribution control module calculates the deviation between the two by comparing the detection result and the preset value. If the detection result deviates from the preset value, the distribution control module will output a control signal in real time to adjust the opening time of the distribution port or the distance from the liquid surface to reduce the deviation and realize the closed-loop control of the distribution liquid amount or flow rate.

[0049] In this way, through real-time detection and closed-loop control of flow / volume, the amount of liquid dispensed each time can be ensured to be highly accurate, greatly improving the accuracy and stability of liquid dispensing.

[0050] In some embodiments, the positioning module 8 in the fully automatic high-precision laboratory dispenser includes a lateral moving component, a longitudinal moving component and an up-and-down moving component, and the linkage movement of the lateral moving component, the longitudinal moving component and the up-and-down moving component controls the three-dimensional spatial positioning of the pipetting arm. Specifically, the lateral moving component can include a precision guide rail, a stepper motor and a lead screw mechanism, which can realize the precise translational movement of the pipetting arm in the left and right directions. The longitudinal moving component also includes a precision guide rail, a stepper motor and a lead screw mechanism to realize the precise movement of the pipetting arm in the front and back directions. The up-and-down moving component includes a lifting platform and a stepper motor, which can carefully control the movement of the pipetting arm in the vertical direction. The three components can realize high-precision micro-displacement through precise transmission ratio design, thereby accurately positioning the pipetting arm. The movement of the three components is centrally controlled by the positioning control module, and linkage control is performed according to the target coordinate instruction to finally determine the accurate position of the pipetting arm in three-dimensional space. The positioning module 8 constitutes a three-dimensional motion platform, so that the pipetting arm can flexibly reach any position in the workspace to meet the needs of various complex liquid distribution.

[0051] In some embodiments, the fully automatic high-precision laboratory dispenser also includes an image recognition module 9, which is connected to the automatic control device 2 and is used to perform image recognition on the containers in the working area to obtain the position and quantity information of the containers. The automatic control device 2 adjusts the motion trajectory of the pipetting arm according to the image recognition result. Specifically, the image acquisition device can be a small industrial camera for shooting the working area scene image. After obtaining the scene image, the outline of each container can be detected by an image processing algorithm (such as shape detection, feature extraction, etc.), and the visual features of the container can be extracted. Then, the image analysis software can identify the position coordinates and quantity of different containers based on the visual features such as the shape, color, and size of the container. The image recognition result is output to the automatic control device 2. The three-dimensional model or reference image of each container is stored in the automatic control device 2. By comparing and aligning the image recognition results and database information, the automatic control device 2 can accurately obtain the three-dimensional coordinate position of each container in the current scene. Based on these container coordinate information, the automatic control device 2 can plan the motion trajectory and action sequence of the pipetting arm, avoid obstacles, and efficiently and quickly transfer liquids to different containers. When the container position changes, the image recognition module 9 can quickly re-identify, allowing the automatic control device 2 to adjust the motion trajectory of the pipetting arm in time.

[0052] In some implementations, the image recognition module 9 in the fully automatic high-precision laboratory dispenser is also used to capture images of the container to obtain a container image, determine the container type and liquid level according to the container image, and feed back the judgment result to the automatic control device 2, so that the automatic control device 2 controls the liquid distribution according to the container type and the liquid level. Specifically, when the container is placed in the operating area of ​​the dispenser, the image recognition module 9 first locates the container and captures its image. This is usually done automatically during the process of transferring the container to the distribution area. The image recognition module 9 analyzes the shape, size and other visual features of the container to determine the type of container (such as a test tube, a culture dish, a beaker, etc.). This step is crucial to determining how to operate the pipetting arm and the distribution port. Also through image analysis, the image recognition module 9 can determine the liquid level in the container. The results of image recognition (container type and liquid level) will be sent back to the automatic control device 2. The automatic control device 2 adjusts the distribution strategy based on this information, such as changing the position of the pipetting arm, adjusting the distribution speed and liquid volume, etc. If the container is deep and the liquid level is low, it may be necessary to extend the descent depth of the pipetting arm to ensure that the liquid can be accurately distributed to the bottom of the container. If the liquid level is already high, the control system will appropriately reduce the liquid distribution speed to prevent overflow or excessive liquid fluctuations. During the liquid distribution process, the image recognition module 9 can continuously monitor the liquid level changes and adjust the distribution strategy in real time to ensure the accuracy and safety of the distribution process.

[0053] In some embodiments, the human-computer interaction device 3 in the fully automatic high-precision laboratory dispenser includes a display screen 10 and a voice playback module 11, the display screen 10 is used to display an interactive menu and view the current liquid dispensing state, and the voice playback module 11 is used to play the liquid dispensing completion information. Specifically, the display screen 10 adopts a touch screen design, and can display an interactive menu, such as setting a liquid dispensing parameter interface, for setting parameters such as sample quantity, liquid aspiration, and distribution amount. The liquid dispensing process monitoring interface displays the current sample number, completion progress and other information in real time. The liquid dispensing data interface displays the precise data of each liquid dispensing, such as liquid aspiration volume, distribution volume, time, etc. The system status interface displays the current working status of the device, error code and other system information. The operation guide interface provides step guidance to guide the user to operate. In practical applications, other display contents can also be included, which can be set according to the actual needs of the user, and are not limited here. Such an intuitive graphical interface design simplifies the operation of complex equipment, and users can view various information and perform interactive control.

[0054] The voice playback module 11 includes a voice synthesis chip, which can play preset voice prompts, such as: before performing dangerous operations, voice confirmation is required, and the voice broadcast of the current steps is broadcast. After the liquid separation program is completed, a voice prompt is used. When the system fails, a voice alarm is issued. The introduction of the voice playback module 11 avoids the trouble of users needing to check the screen frequently, can maintain the continuity of other work, and also makes long-distance remote control possible.

[0055] In some embodiments, the fully automatic high-precision laboratory dispenser also includes a pneumatic transmission distribution module 12, which is associated with the automatic control device 2, and the pneumatic transmission distribution module 12 includes a pneumatic actuator and a pneumatic control unit, the output end of the pneumatic actuator is connected to the distribution needle; an air source providing unit is used to provide compressed air; the pneumatic control unit is used to control the air source providing unit to provide compressed air to the pneumatic actuator, drive the pneumatic actuator to drive the distribution needle to move to achieve liquid distribution. Specifically, the pneumatic transmission distribution module 12 includes a pneumatic actuator, the end of which is connected to a distribution needle, and the needle can be directly inserted into the source container to be dispensed. Pressurized air is provided by the air source providing unit, and when necessary, the air source provides stable compressed air. The pneumatic control unit includes an electromagnetic valve group, which can switch the ventilation direction of the pneumatic actuator and accurately control the airflow. During operation, the pneumatic control unit first directs the compressed air to one side of the pneumatic actuator, pushes the piston and drives the distribution needle downward to be inserted into the source container. When the corresponding liquid level is reached, the pneumatic control unit switches the ventilation direction and directs the compressed air to the other side of the pneumatic actuator. Driven by the compressed air, the piston of the pneumatic actuator moves back quickly, driving the distribution needle to absorb and use it in the container to be distributed. Then the pneumatic control unit switches the ventilation direction again, the pneumatic actuator piston resets, and the distribution needle moves back to the source container to complete a distribution cycle. The volume of the distribution needle can be designed to be 1-10 ml. By setting the working stroke of the pneumatic actuator, the amount of liquid in each distribution cycle can be accurately controlled. The frequent switching of the electromagnetic valve can reach more than 10 times per second, which can achieve high-frequency liquid separation at a faster speed. In this way, the impact brought by the pneumatic transmission distribution module 12 can also overcome the viscosity of some dense liquids, realize the high-speed and high-precision distribution function of small-volume liquids, and significantly improve the liquid separation efficiency.

[0056] The fully automatic high-precision laboratory dispenser of this embodiment includes: a high-precision liquid dispensing device 1, an automatic control device 2, a human-computer interaction device 3, a cleaning device 4, a quantitative liquid aspiration device 5, a distribution device 6, a liquid detection unit 7, a positioning module 8, an image recognition module 9, a display screen 10, a voice playback module 11, and a pneumatic transmission distribution module 12.

[0057] A high-precision liquid dispensing device 1, used for performing aspiration and precise dispensing of liquid samples;

[0058] An automatic control device 2, connected to the high-precision liquid separation device 1, and used to control the action of the liquid separation device according to preset parameters;

[0059] A human-machine interaction device 3, connected to the automatic control device 2, for controlling the automatic control device 2 and displaying the device status according to the liquid dispensing parameters input by the user;

[0060] A cleaning device 4, which is associated with the automatic control device 2, and includes a cleaning liquid storage tank for storing cleaning liquid; a cleaning pump for extracting the cleaning liquid; a cleaning nozzle for spraying the cleaning liquid; and a cleaning control module for controlling the extraction and spraying process of the cleaning pump to achieve automatic cleaning of the convection path;

[0061] A quantitative liquid aspiration device 5, which is associated with the automatic control device 2, and includes a liquid aspiration pump with a set volume, used to aspirate the set volume of liquid with high precision; a liquid level sensor, which monitors and feeds back the liquid aspiration amount data in real time; and a liquid aspiration control module, which is connected to the liquid aspiration pump and the liquid level sensor, and is used to control the operation of the liquid aspiration pump according to the set volume, and realize closed-loop control according to the liquid aspiration amount data;

[0062] A dispensing device 6, which is associated with the automatic control device 2, and includes a pipetting arm for movably connecting to a liquid transmission pipeline; a dispensing port, which is arranged at the end of the pipetting arm, for dispensing liquid; a positioning module 8, which is used to control the movement and positioning of the pipetting arm in a three-dimensional space; and a dispensing control module, which controls the movement of the pipetting arm according to the position of the target container to achieve liquid dispensing;

[0063] A liquid detection unit 7, which is arranged at the dispensing port and is used to detect liquid parameters during the dispensing process, wherein the liquid parameters include the volume or flow rate of the dispensed liquid. The dispensing control module is also used to adjust the dispensing process according to the detection result of the liquid parameters;

[0064] The positioning module 8 includes a lateral moving component, a longitudinal moving component and an up-and-down moving component, and the linkage movement of the lateral moving component, the longitudinal moving component and the up-and-down moving component controls the three-dimensional spatial positioning of the pipetting arm;

[0065] An image recognition module 9, which is connected to the automatic control device 2 and is used to perform image recognition on the containers in the working area to obtain the position and quantity information of the containers, and the automatic control device 2 adjusts the motion trajectory of the pipetting arm according to the image recognition result; and is also used to perform image acquisition on the container to obtain a container image, determine the container type and liquid level according to the container image, and feed back the determination result to the automatic control device 2, so that the automatic control device 2 controls the liquid distribution according to the container type and the liquid level;

[0066] A display screen 10 and a voice playing module 11, wherein the display screen 10 is used to display an interactive menu and view the current dispensing status, and the voice playing module 11 is used to play the dispensing completion information;

[0067] A pneumatic transmission distribution module 12 is associated with the automatic control device 2. The pneumatic transmission distribution module 12 includes a pneumatic actuator and a pneumatic control unit. The output end of the pneumatic actuator is connected to the distribution needle; an air source providing unit is used to provide compressed air; the pneumatic control unit is used to control the air source providing unit to provide compressed air to the pneumatic actuator, driving the pneumatic actuator to drive the distribution needle to move to achieve liquid distribution.

[0068] As described above, a fully automatic and high-precision liquid separation operation can be achieved while the liquid separation method in the prior art is complicated to operate and has low liquid separation precision and requires certain manual participation.

Claims

1. A fully automatic high-precision laboratory liquid dispenser, characterized in that: include: High-precision dispensing device for aspirating and accurately dispensing liquid samples; An automatic control device, connected to the high-precision liquid separation device, and used to control the action of the liquid separation device according to preset parameters; The human-computer interaction device is connected to the automatic control device and is used to control the automatic control device and display the device status according to the liquid dispensing parameters input by the user.

2. A fully automatic high-precision laboratory liquid dispenser according to claim 1, characterized in that: It also includes a cleaning device, which is associated with the automatic control device, and includes a cleaning liquid storage tank for storing cleaning liquid; a cleaning pump for extracting the cleaning liquid; and a cleaning nozzle for spraying the cleaning liquid; The cleaning control module is used to control the extraction and injection process of the cleaning pump to achieve automatic cleaning of the convection path.

3. A fully automatic high-precision laboratory liquid dispenser according to claim 1, characterized in that: It also includes a quantitative liquid aspiration device, which is associated with the automatic control device. The quantitative liquid aspiration device includes a liquid aspiration pump with a set volume, which is used to aspirate a set volume of liquid; a liquid level sensor, which monitors and feeds back liquid aspiration volume data in real time; and a liquid aspiration control module, which connects the liquid aspiration pump and the liquid level sensor, and is used to control the operation of the liquid aspiration pump according to the set volume, and realize closed-loop control according to the liquid aspiration volume data.

4. A fully automatic high-precision laboratory liquid dispenser according to claim 1, characterized in that: It also includes a dispensing device, which is associated with the automatic control device. The dispensing device includes a pipetting arm for movably connecting a liquid transmission pipeline; a dispensing port, which is arranged at the end of the pipetting arm and is used to distribute liquid; a positioning module, which is used to control the movement and positioning of the pipetting arm in three-dimensional space; and a distribution control module, which controls the movement of the pipetting arm according to the target container position to achieve liquid distribution.

5. A fully automatic high-precision laboratory liquid dispenser according to claim 4, characterized in that: The dispensing device also includes a liquid detection unit, which is arranged at the dispensing port and is used to detect liquid parameters during the dispensing process. The liquid parameters include the volume or flow rate of the distributed liquid. The dispensing control module is also used to adjust the dispensing process according to the detection results of the liquid parameters.

6. A fully automatic high-precision laboratory liquid dispenser according to claim 4, characterized in that: The positioning module comprises a lateral moving component, a longitudinal moving component and an up-and-down moving component. The linkage movement of the lateral moving component, the longitudinal moving component and the up-and-down moving component controls the three-dimensional spatial positioning of the pipetting arm.

7. A fully automatic high-precision laboratory liquid dispenser according to claim 1, characterized in that: It also includes an image recognition module, which is connected to the automatic control device and is used to perform image recognition on the containers in the working area to obtain the position and quantity information of the containers. The automatic control device adjusts the movement trajectory of the pipetting arm according to the image recognition result.

8. A fully automatic high-precision laboratory liquid dispenser according to claim 7, characterized in that: The image recognition module is also used to capture the image of the container to obtain a container image, determine the container type and the liquid level according to the container image, and feed back the determination result to the automatic control device so that the automatic control device controls the liquid distribution according to the container type and the liquid level.

9. A fully automatic high-precision laboratory liquid dispenser according to claim 1, characterized in that: The human-computer interaction device includes a display screen and a voice playing module. The display screen is used to display an interactive menu and view the current liquid dispensing status, and the voice playing module is used to play liquid dispensing completion information.

10. A fully automatic high-precision laboratory liquid dispenser according to claim 1, characterized in that: It also includes a pneumatic transmission distribution module, which is associated with the automatic control device. The pneumatic transmission distribution module includes a pneumatic actuator and a pneumatic control unit, and the output end of the pneumatic actuator is connected to the distribution needle; an air source providing unit is used to provide compressed air; the pneumatic control unit is used to control the air source providing unit to provide compressed air to the pneumatic actuator, drive the pneumatic actuator to drive the distribution needle to move to achieve liquid distribution.

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