A waste liquid recovery and driving device for a fully automatic antibody hybridization instrument

By designing a waste liquid recovery and driving device for a fully automatic antibody hybridizer, the problems of low antibody recovery and low experimental efficiency caused by the unified discharge of waste liquid and antibodies in the prior art are solved, and automatic separation and recycling of waste liquid and antibodies are realized, and experimental efficiency and recovery are improved.

CN222734164UActive Publication Date: 2025-04-08CHONGQING SICHENGRUI TECH CO LTD
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Patent Information

Application Number
CN202421123095.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-22
Publication Date
2025-04-08
Estimated Expiration
2034-05-22

AI Technical Summary

Technical Problem

In the prior art, the waste liquid after incubation is uniformly discharged with the antibodies, resulting in a decrease in the antibody recovery rate, and manual discharge of waste liquid is wasted labor and time, affecting the experimental efficiency.

Method used

A fully automatic antibody hybridizer waste liquid recycling and driving device is designed, including a driving table assembly, tank body, antibody recycling box, slide rail, slider and rack plate. The gears and rack plates are driven by a servo motor to realize automatic separation and recycling of waste liquid and antibodies.

Benefits of technology

Automatic separation and emission of waste liquid, primary and secondary antibodies is achieved, and antibody recovery efficiency is improved, labor and time is saved, testing costs is reduced, and experimental efficiency and progress is improved.

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Abstract

The utility model relates to the field of biological technology, and specifically discloses a waste liquid recovery and driving device of a fully automatic antibody hybridization instrument, including a driving platform assembly, a tank body, a first antibody recovery box, a second antibody recovery box, a slide rail, a slider and a rack plate, each slider is slidably connected to the slide rail, the tank body is fixedly connected to a plurality of sliders, the tank body has a waste liquid tank and a plurality of antibody tanks, each first antibody recovery box and each second antibody recovery box are respectively embedded in the corresponding antibody tank, and each first antibody recovery box and each second antibody recovery box are spaced apart, the rack plate is fixedly connected to the tank body, and the driving platform assembly is arranged on one side of the tank body. It can highly simulate manual operation, realize the separation and discharge of waste liquid, primary antibody and secondary antibody, improve the recovery efficiency of primary antibody and secondary antibody, save a lot of labor and time, greatly reduce the test cost, and improve the efficiency and progress of the entire experiment.
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Description

Technical Field

[0001] The utility model relates to the technical field of biology, in particular to a waste liquid recovery and driving device of a full-automatic antibody hybridization instrument. Background Art

[0002] Currently, in protein-related laboratories, there are many experiments involving immune responses of various antibodies. In the experiments, specific antibodies need to react with membrane supports carrying the experimenter's specific proteins, and the various antibodies involved need to be washed multiple times.

[0003] However, in the prior art, the waste liquid and antibodies after incubation are discharged uniformly, resulting in a reduced recovery rate of the antibodies. At the same time, manual discharge of the waste liquid wastes a lot of manpower and time, thus affecting the efficiency of the experiment. Utility Model Content

[0004] The purpose of the utility model is to provide a waste liquid recovery and drive device for a fully automatic antibody hybridization instrument, aiming to solve the technical problems in the prior art that the waste liquid and antibodies after incubation are discharged uniformly, resulting in a reduced antibody recovery rate, and manual discharge of the waste liquid wastes a lot of manpower and time, thereby affecting the experimental efficiency.

[0005] To achieve the above-mentioned purpose, the utility model adopts a waste liquid recovery and driving device of a fully automatic antibody hybridization instrument, including a driving platform assembly, a trough body, a first antibody recovery box, a second antibody recovery box, a slide rail, a slider and a rack plate. There are multiple sliders, each of which is slidably connected to the slide rail and is respectively located at the upper end of the slide rail. The trough body is fixedly connected to multiple sliders and is located at the upper ends of multiple sliders. The trough body has a waste liquid trough and multiple antibody troughs. There are multiple first antibody recovery boxes and multiple second antibody recovery boxes. Each first antibody recovery box and each second antibody recovery box are respectively embedded in the corresponding antibody trough, and each first antibody recovery box is spaced apart from each second antibody recovery box. The rack plate is fixedly connected to the trough body and is located at the lower end of the trough body. The driving platform assembly is arranged on one side of the trough body, and the output end of the driving platform assembly is adapted to the rack plate.

[0006] Among them, the driving platform assembly includes a mounting plate, a vertical plate, a servo motor and a gear. The mounting plate is arranged on one side of the trough body, the vertical plate is fixedly connected to the mounting plate and is located at the upper end of the mounting plate, the servo motor is fixedly connected to the vertical plate and is located on one side of the vertical plate, and the output end of the servo motor passes through the vertical plate and is fixedly connected to the gear. The gear is sleeved on the outer wall of the output end of the servo motor, and the gear and the rack plate are adapted to each other.

[0007] Among them, the waste liquid recovery and driving device of the fully automatic antibody hybridization instrument also includes a column rod, and the number of the column rods is multiple. The two ends of each column rod are fixedly connected to the corresponding first antibody recovery box and the second antibody recovery box, and are respectively located inside the corresponding first antibody recovery box and the second antibody recovery box.

[0008] Among them, the waste liquid recovery and drive device of the fully automatic antibody hybridization instrument also includes a drain valve pipe, and the number of the drain valve pipes is multiple, each of the drain valve pipes is respectively arranged on one side of the trough body, and one end of each drain valve pipe respectively passes through the trough body and is connected to the waste liquid tank.

[0009] The beneficial effects of the waste liquid recovery and driving device of the fully automatic antibody hybridization instrument of the present invention are as follows: the driving platform assembly drives the trough body horizontally, and the corresponding first antibody recovery box, the second antibody recovery box and the waste liquid trough are moved to the lower end of the wedge-shaped mouth of the incubation box according to needs, and the corresponding liquid is poured into the designated position, which can highly simulate manual operation to achieve the separation and discharge of waste liquid, primary antibody and secondary antibody, improve the recovery efficiency of primary antibody and secondary antibody, save a lot of labor and time, greatly reduce the test cost, and improve the efficiency and progress of the entire experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0011] Figure 1 The utility model is a structural diagram of a waste liquid recovery and driving device of a fully automatic antibody hybridization instrument.

[0012] Figure 2 The utility model is a top view of a waste liquid recovery and driving device of a fully automatic antibody hybridization instrument.

[0013] Figure 3 The utility model is a bottom view of a waste liquid recovery and driving device of a fully automatic antibody hybridization instrument.

[0014] Figure 4 This is a structural schematic diagram of a waste liquid recovery and driving device of a fully automatic antibody hybridization instrument of the present invention without the first antibody recovery box and the second antibody recovery box being placed therein.

[0015] Figure 5The utility model is a schematic structural diagram of a waste liquid recovery and drive device of a fully automatic antibody hybridization instrument.

[0016] 1-mounting plate, 2-vertical plate, 3-servo motor, 4-gear, 5-trough, 6-first antibody recovery box, 7-second antibody recovery box, 8-slide rail, 9-slider, 10-rack plate, 11-column, 12-drain valve pipe, 13-waste liquid tank, 14-antibody tank. DETAILED DESCRIPTION

[0017] See also Figures 1 to 5 The utility model provides a waste liquid recovery and driving device for a fully automatic antibody hybridization instrument, comprising a driving platform assembly, a trough body 5, a first antibody recovery box 6, a second antibody recovery box 7, a slide rail 8, a slider 9 and a rack plate 10, wherein the number of the sliders 9 is multiple, each of the sliders 9 is slidably connected to the slide rail 8 and is respectively located at the upper end of the slide rail 8, the trough body 5 is fixedly connected to the multiple sliders 9 and is located at the upper end of the multiple sliders 9, the trough body 5 has a waste liquid trough 13 and multiple antibody troughs 14, the number of the first antibody recovery box 6 is multiple, the number of the second antibody recovery box 7 is multiple, each of the first antibody recovery box 6 and each of the second antibody recovery box 7 is respectively embedded in the corresponding antibody trough 14, and each of the first antibody recovery box 6 and each of the second antibody recovery box 7 is spaced apart, the rack plate 10 is fixedly connected to the trough body 5 and is located at the lower end of the trough body 5, the driving platform assembly is arranged on one side of the trough body 5, and the output end of the driving platform assembly is adapted to the rack plate 10.

[0018] Furthermore, the drive platform assembly includes a mounting plate 1, a vertical plate 2, a servo motor 3 and a gear 4, the mounting plate 1 is arranged on one side of the trough body 5, the vertical plate 2 is fixedly connected to the mounting plate 1, and is located at the upper end of the mounting plate 1, the servo motor 3 is fixedly connected to the vertical plate 2, and is located on one side of the vertical plate 2, and the output end of the servo motor 3 passes through the vertical plate 2 and is fixedly connected to the gear 4, the gear 4 is sleeved on the outer wall of the output end of the servo motor 3, and the gear 4 and the rack plate 10 are adapted to each other.

[0019] Furthermore, the waste liquid recovery and driving device of the fully automatic antibody hybridization instrument also includes a column rod 11, and the number of the column rod 11 is multiple. The two ends of each column rod 11 are fixedly connected to the corresponding first antibody recovery box 6 and the second antibody recovery box 7, and are respectively located inside the corresponding first antibody recovery box 6 and the second antibody recovery box 7.

[0020] Furthermore, the waste liquid recovery and drive device of the fully automatic antibody hybridization instrument also includes a drain valve pipe 12, and the number of the drain valve pipe 12 is multiple, each of the drain valve pipe 12 is respectively arranged on one side of the tank body 5, and one end of each of the drain valve pipe 12 respectively passes through the tank body 5 and is connected to the waste liquid tank 13.

[0021] In this embodiment, the slide rails 8 are used to install and fix the plurality of sliders 9, and the plurality of sliders 9 support the trough body 5. The mounting plate 1 supports and fixes the vertical plate 2, and the vertical plate 2 supports the servo motor 3. The wedge-shaped mouth of the incubation box is located at the upper end of the waste liquid tank 13, and the first antibody recovery box 6 and the second antibody recovery box 7 are placed in the corresponding antibody tank 14. When the waste liquid is processed, the servo motor 3 is not driven, and the incubation box is directly subjected to a seesaw motion so that the waste liquid is discharged from the wedge-shaped mouth and enters the waste liquid tank 13. When the primary antibody is discharged, the servo motor 3 is driven to rotate forward, thereby driving the gear 4 to rotate, and the gear 4 is meshed with the rack plate 10 to drive the rack plate 10 to move to the left, and under the adaptation of the slide rails 8 and the sliders 9, The trough body 5 is moved until the first antibody recovery box 6 moves to the bottom of the incubation box, and the primary antibody in the incubation box is discharged into the first antibody recovery box 6. When the secondary antibody is discharged, the servo motor 3 is driven to reverse, thereby driving the gear 4 to rotate. Through the meshing fit of the gear 4 and the rack plate 10, the rack plate 10 is driven to move to the right, and under the adaptation of the slide rail 8 and the slider 9, the trough body 5 is moved until the second antibody recovery box 7 moves to the bottom of the incubation box, and the secondary antibody in the incubation box is discharged into the second antibody recovery box 7. After the test is completed, the waste liquid in the waste liquid tank 13 can be discharged through the drain valve pipe 12, and the first antibody recovery box 6 and the second antibody recovery box 7 are supported by the column 11 to recover the primary antibody and the secondary antibody for secondary use respectively.

[0022] The above disclosure is only a preferred embodiment of the present invention, and certainly cannot be used to limit the scope of rights of the present invention. Ordinary technicians in this field can understand that all or part of the processes of the above embodiment and equivalent changes made in accordance with the claims of the present invention are still within the scope of the utility model.

Claims

1. A waste liquid recovery and driving device for a fully automatic antibody hybridization instrument, characterized in that: It includes a driving platform assembly, a trough body, a first antibody recovery box, a second antibody recovery box, a slide rail, a slider and a rack plate. There are multiple sliders, each of which is slidably connected to the slide rail and is respectively located at the upper end of the slide rail. The trough body is fixedly connected to the multiple sliders and is located at the upper ends of the multiple sliders. The trough body has a waste liquid trough and multiple antibody troughs. There are multiple first antibody recovery boxes and multiple second antibody recovery boxes. Each of the first antibody recovery boxes and each of the second antibody recovery boxes are respectively embedded in the corresponding antibody troughs, and each of the first antibody recovery boxes is spaced apart from each of the second antibody recovery boxes. The rack plate is fixedly connected to the trough body and is located at the lower end of the trough body. The driving platform assembly is arranged on one side of the trough body, and the output end of the driving platform assembly is adapted to the rack plate.

2. The waste liquid recovery and driving device of a fully automatic antibody hybridization instrument as claimed in claim 1, characterized in that: The driving platform assembly includes a mounting plate, a vertical plate, a servo motor and a gear. The mounting plate is arranged on one side of the trough body, the vertical plate is fixedly connected to the mounting plate and is located at the upper end of the mounting plate, the servo motor is fixedly connected to the vertical plate and is located on one side of the vertical plate, and the output end of the servo motor passes through the vertical plate and is fixedly connected to the gear, the gear is sleeved on the outer wall of the output end of the servo motor, and the gear and the rack plate are adapted to each other.

3. The waste liquid recovery and driving device of a fully automatic antibody hybridization instrument as claimed in claim 2, characterized in that: The waste liquid recovery and driving device of the fully automatic antibody hybridization instrument also includes a column rod, and the number of the column rods is multiple. The two ends of each column rod are respectively fixedly connected to the corresponding first antibody recovery box and the second antibody recovery box, and are respectively located inside the corresponding first antibody recovery box and the second antibody recovery box.

4. The waste liquid recovery and driving device of a fully automatic antibody hybridization instrument as claimed in claim 3, characterized in that: The waste liquid recovery and driving device of the fully automatic antibody hybridization instrument also includes a drain valve pipe, and the number of the drain valve pipes is multiple, each of the drain valve pipes is respectively arranged on one side of the trough body, and one end of each of the drain valve pipes passes through the trough body and is connected to the waste liquid trough.