Chromatographic column fixing device

Abstract

The utility model discloses a chromatographic column fixing device, which relates to the technical field of chromatographic columns. In view of the problems raised in the background technology that chromatographic columns of different specifications cannot be clamped and fixed, the scope of application is low, the chromatographic columns cannot be insulated, the chromatographic columns are easily changed due to rapid temperature changes, and the practicability is low, the following scheme is proposed, including a base, a heat preservation mechanism is provided on the top of the base, the heat preservation mechanism includes two heat preservation side plates respectively connected to the outer walls on both sides of the top of the base by bolts and a top cover connected to the outer walls of the tops of the two heat preservation side plates by bolts, and a lifting mechanism is provided on the top of the base. The utility model can adjust the temperature at the chromatographic column in real time, prevent the filling situation of the filler in the chromatographic column from changing due to rapid temperature changes, improve practicability, can clamp and fix chromatographic columns of different specifications, and improve the scope of application.

Description

Technical Field

[0001] The utility model relates to the technical field of chromatographic columns, in particular to a chromatographic column fixing device. Background Art

[0002] The chromatographic column consists of a column tube, a pressure cap, a ferrule (sealing ring), a sieve plate (filter), joints, screws, etc. It can be divided into two categories: packed columns and open tube columns. Most of them are made of metal or glass, and have shapes such as straight tubes, coils, and U-shaped tubes. Liquid chromatography usually uses packed columns.

[0003] After searching, a Chinese patent (application number "201720733024.7") discloses "a rotatable glass chromatographic column fixing device". The above device includes a base, a horizontal adjustment member is provided at the lower part of the base, a level meter is provided on the base, and a fixed frame includes a rotating disk, a rotating shaft and a fixed bracket. One end of the rotating shaft is fixed to the base, and the fixed bracket is further fixed by the rotating shaft. At least one fixed bracket is provided with a liquid receiving tray on the outside; a plurality of fixing clips are provided on the fixed bracket, and the chromatographic column is fixed by the fixing clips. The liquid receiving bottle is further arranged on the liquid receiving tray. However, the above device has the following problems during use:

[0004] 1. When fixing the chromatographic column, it is impossible to clamp and fix chromatographic columns of different specifications, and the scope of application is low;

[0005] 2. When the chromatographic column is fixed, the chromatographic column cannot be kept warm. The filling condition inside the chromatographic column is easily changed due to rapid temperature changes, which has low practicality. Utility Model Content

[0006] The utility model provides a chromatographic column fixing device, which solves the problems that the comparative documents cannot clamp and fix chromatographic columns of different specifications, have a low scope of application, cannot insulate the chromatographic columns, and the chromatographic columns are easily changed due to rapid changes in temperature, causing changes in the filling conditions inside the chromatographic columns, and have low practicality.

[0007] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0008] A chromatographic column fixing device comprises a base, a heat preservation mechanism is arranged on the top of the base, the heat preservation mechanism comprises two heat preservation side plates respectively connected to the outer walls on both sides of the top of the base by bolts and a top cover connected to the outer walls of the tops of the two heat preservation side plates by bolts, a lifting mechanism is arranged on the top of the base, the lifting mechanism comprises a screw connected to the outer wall of the top of the base by a bearing, a lifting plate slidably sleeved on the outer wall of the screw, a threaded cylinder screwed on the outer wall of the screw and a fixing plate connected to the outer wall of the upper part of the screw by a bearing, chromatographic column mounting grooves distributed at equal distances are opened on the outer walls on both sides of the lifting plate and the fixing plate, a plurality of clamping components are arranged on the outer walls on both sides of the lifting plate and the fixing plate, the clamping component comprises a mounting block, a screw rod penetrating and screwed on the outer wall of one side of the mounting block, a clamping block and a rubber pad embedded in the inner wall of the chromatographic column mounting groove, a temperature regulating component is arranged on one side of the heat preservation side plate, and the temperature regulating component comprises a mounting cylinder, a heating wire embedded in the mounting cylinder and a fan embedded in the mounting cylinder.

[0009] Preferably, a sealed door is hinged on the outer wall of one side of the two heat-insulating side panels, and a through hole is opened on the lower outer wall of one side of the four sealed doors.

[0010] Preferably, the threaded tube is connected to the bottom outer wall of the lifting plate by bolts, and two sliding rods are fixed on the outer walls on both sides of the lifting plate, and the two sides of the fixed plate are respectively connected to the upper outer walls on one side of the two insulation side plates by bolts.

[0011] Preferably, two slide grooves are formed on the outer walls of one side of the two insulation side panels, and four slide rods are slidably installed in the four slide grooves respectively.

[0012] According to the above scheme, by rotating the screw rod, the screw rod drives the threaded barrel and the lifting plate to move, thereby adjusting the distance between the lifting plate and the fixed plate.

[0013] Preferably, the mounting block is connected to the outer wall of one side of the chromatographic column mounting groove by bolts, a connecting plate is connected to the outer wall of one end of the screw rod by a bearing, and the connecting plate is slidably installed on the inner wall of the chromatographic column mounting groove, and the clamping block is fixed on the outer wall of one side of the connecting plate.

[0014] According to the above scheme, by rotating the screw rod, the screw rod drives the connecting plate to move along the inner wall of the chromatographic column installation groove, thereby driving the clamping block to move, and the clamping block and the rubber pad cooperate with each other to clamp and fix the chromatographic column.

[0015] Preferably, the mounting tube is connected to the lower outer wall on one side of one of the insulation side panels via a flange, and an air inlet is provided on the lower outer wall on one side of the insulation side panel.

[0016] Through the above scheme, a temperature sensor is installed on the base. When the temperature at the chromatographic column changes, the heating wire and the fan are started to adjust the temperature inside the chromatographic column.

[0017] The beneficial effects of the utility model are:

[0018] 1. A heat preservation mechanism and a temperature regulating component are provided, and a temperature sensor is installed on the base. When the temperature at the chromatographic column changes, the heating wire and the fan are started to adjust the temperature inside the chromatographic column. The temperature at the chromatographic column can be adjusted in real time to prevent the rapid temperature change from causing changes in the filling condition of the filler in the chromatographic column, thereby improving practicality.

[0019] 2. A lifting mechanism and a clamping assembly are provided. The screw rod is rotated to drive the threaded barrel and the lifting plate to move, thereby adjusting the distance between the lifting plate and the fixed plate. The screw rod is rotated to drive the connecting plate to move along the inner wall of the chromatographic column installation groove, thereby driving the clamping block to move. The clamping block and the rubber pad cooperate with each other to clamp and fix the chromatographic column. The chromatographic columns of different specifications can be clamped and fixed, thereby improving the scope of application.

[0020] In summary, the utility model can adjust the temperature of the chromatographic column in real time, prevent the rapid temperature change from causing changes in the filling condition of the filler in the chromatographic column, improve practicality, and can clamp and fix chromatographic columns of different specifications, thereby increasing the scope of application. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 This is a schematic diagram of the main three-dimensional structure of a chromatography column fixing device proposed by the utility model.

[0022] Figure 2 This is a schematic diagram of the front cross-sectional structure of a chromatographic column fixing device proposed by the utility model.

[0023] Figure 3 The utility model provides a schematic diagram of the heat preservation mechanism of the chromatographic column fixing device.

[0024] Figure 4 This is a schematic diagram of the front structural view of a lifting mechanism of a chromatographic column fixing device proposed by the utility model.

[0025] Figure 5 The utility model provides a schematic diagram of the bottom structure of a lifting mechanism of a chromatography column fixing device.

[0026] Figure 6 The utility model provides a schematic diagram of the structure of a clamping assembly of a chromatographic column fixing device.

[0027] Figure 7The utility model provides a schematic cross-sectional structure diagram of a temperature regulating component of a chromatographic column fixing device.

[0028] In the figure: 1. base; 2. insulation mechanism; 201. insulation side plate; 202. top cover; 203. sealing door; 3. lifting mechanism; 301. screw; 302. lifting plate; 303. threaded barrel; 304. slide rod; 305. fixing plate; 31. chromatographic column mounting groove; 4. slide groove; 5. clamping assembly; 501. mounting block; 502. screw rod; 503. connecting plate; 504. clamping block; 505. rubber pad; 6. temperature control assembly; 601. mounting barrel; 602. heating wire; 603. fan. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0030] Example 1, reference Figure 1-3 and Figure 7 A chromatographic column fixing device comprises a base 1, a heat preservation mechanism 2 is arranged on the top of the base 1, the heat preservation mechanism 2 comprises two heat preservation side plates 201 respectively connected to the outer walls on both sides of the top of the base 1 by bolts and a top cover 202 connected to the outer walls of the tops of the two heat preservation side plates 201 by bolts, a sealing door 203 is hinged on the outer wall of one side of the two heat preservation side plates 201, through holes are opened on the lower outer walls of one side of the four sealing doors 203, a temperature regulating component 6 is arranged on one side of the heat preservation side plate 201, the temperature regulating component 6 comprises a mounting tube 601, a heating wire 602 embedded in the mounting tube 601 and a fan 603 embedded in the mounting tube 601, the mounting tube 601 is connected to the lower outer wall of one side of one of the heat preservation side plates 201 by a flange, and an air inlet is opened on the lower outer wall of one side of the heat preservation side plate 201.

[0031] Example 2, reference Figure 1-2 and Figure 4-6, a chromatographic column fixing device also includes a lifting mechanism 3, the lifting mechanism 3 includes a screw 301 connected to the top outer wall of the base 1 through a bearing, a lifting plate 302 slidably sleeved on the outer wall of the screw 301, a threaded barrel 303 screwed on the outer wall of the screw 301 and a fixing plate 305 connected to the upper outer wall of the screw 301 through a bearing, the threaded barrel 303 is connected to the bottom outer wall of the lifting plate 302 by bolts, two sliding rods 304 are fixed on the outer walls on both sides of the lifting plate 302, and the fixing plate 305 is respectively connected to the upper outer wall of one side of the two insulation side plates 201 by bolts, and the outer walls on both sides of the lifting plate 302 and the fixing plate 305 are opened with chromatographic column mounting grooves 31 distributed at equal distances, and the two Two slide grooves 4 are provided on the outer wall of one side of each insulation side plate 201, and four slide rods 304 are slidably installed in the four slide grooves 4 respectively. A plurality of clamping components 5 are provided on the outer walls on both sides of the lifting plate 302 and the fixing plate 305. The clamping component 5 includes a mounting block 501, a screw rod 502 penetrating and screwed on the outer wall of one side of the mounting block 501, a clamping block 504 and a rubber pad 505 embedded on the inner wall of the chromatographic column mounting groove 31. The mounting block 501 is connected to the outer wall of one side of the chromatographic column mounting groove 31 by bolts, and a connecting plate 503 is connected to the outer wall of one end of the screw rod 502 by a bearing. The connecting plate 503 is slidably installed on the inner wall of the chromatographic column mounting groove 31, and the clamping block 504 is fixed on the outer wall of one side of the connecting plate 503.

[0032] Working principle: Rotate the screw 301, the screw 301 drives the threaded tube 303 and the lifting plate 302 to move, and then adjust the distance between the lifting plate 302 and the fixed plate 305; rotate the screw 502, the screw 502 drives the connecting plate 503 to move along the inner wall of the chromatographic column mounting groove 31, and then drives the clamping block 504 to move; the clamping block 504 and the rubber pad 505 cooperate with each other to clamp and fix the chromatographic column; install a temperature sensor on the base 1; when the temperature at the chromatographic column changes, start the heating wire 602 and the fan 603 to adjust the temperature inside the chromatographic column.

[0033] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A chromatographic column fixing device, comprising a base (1), characterized in that: A heat preservation mechanism (2) is provided on the top of the base (1), and the heat preservation mechanism (2) comprises two heat preservation side plates (201) respectively connected to the outer walls on both sides of the top of the base (1) by bolts, and a top cover (202) connected to the outer walls of the tops of the two heat preservation side plates (201) by bolts; A lifting mechanism (3) is provided at the top of the base (1), and the lifting mechanism (3) comprises a screw (301) connected to the outer wall of the top of the base (1) via a bearing, a lifting plate (302) slidably sleeved on the outer wall of the screw (301), a threaded cylinder (303) screwed on the outer wall of the screw (301), and a fixing plate (305) connected to the upper outer wall of the screw (301) via a bearing; The outer walls of both sides of the lifting plate (302) and the fixing plate (305) are provided with chromatographic column installation grooves (31) distributed at equal distances; A plurality of clamping assemblies (5) are provided on the outer walls of both sides of the lifting plate (302) and the fixing plate (305), and the clamping assemblies (5) include a mounting block (501), a screw rod (502) penetrating through and screwed to the outer wall of one side of the mounting block (501), a clamping block (504), and a rubber pad (505) embedded on the inner wall of the chromatographic column mounting groove (31); A temperature regulating assembly (6) is provided on one side of the heat-insulating side plate (201), and the temperature regulating assembly (6) comprises a mounting tube (601), a heating wire (602) embedded in the mounting tube (601), and a fan (603) embedded in the mounting tube (601).

2. A chromatographic column fixing device according to claim 1, characterized in that: A sealed door (203) is hinged on the outer wall of one side of the two heat-insulating side panels (201), and a through hole is opened on the lower outer wall of one side of the four sealed doors (203).

3. A chromatographic column fixing device according to claim 1, characterized in that: The threaded cylinder (303) is connected to the bottom outer wall of the lifting plate (302) by bolts, and two sliding rods (304) are fixedly provided on the outer walls on both sides of the lifting plate (302). The two sides of the fixed plate (305) are respectively connected to the upper outer walls on one side of the two insulation side plates (201) by bolts.

4. A chromatographic column fixing device according to claim 3, characterized in that: Two slide grooves (4) are respectively formed on the outer walls of one side of the two heat-insulating side plates (201), and four slide rods (304) are respectively slidably installed in the four slide grooves (4).

5. A chromatographic column fixing device according to claim 1, characterized in that: The mounting block (501) is connected to the outer wall of one side of the chromatographic column mounting groove (31) by means of bolts; a connecting plate (503) is connected to the outer wall of one end of the screw rod (502) by means of a bearing, and the connecting plate (503) is slidably mounted on the inner wall of the chromatographic column mounting groove (31); and the clamping block (504) is fixedly mounted on the outer wall of one side of the connecting plate (503).

6. A chromatography column fixing device according to claim 1, characterized in that: The installation tube (601) is connected to the lower outer wall of one side of the heat-insulating side plate (201) via a flange, and an air inlet is provided on the lower outer wall of one side of the heat-insulating side plate (201).

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