Reaction kettle for preparing amlodipine besylate tablets

Abstract

The utility model relates to the technical field of reaction kettles, and discloses a reaction kettle for preparing amlodipine besylate tablets, which comprises a reaction kettle component and a blanking component fixedly connected with the lower bottom surface of the reaction kettle component, the reaction kettle component comprises a reaction kettle body, a stirring motor is mounted at the top end of the reaction kettle body, and the stirring motor is connected with the blanking component. The discharging assembly comprises a connecting column fixedly connected with the lower bottom face of the reaction kettle body, one end of the connecting column is fixedly connected with a supporting plate, the upper surface of the supporting plate is fixedly connected with a motor, the output end of the motor is fixedly connected with a half gear, and the half gear is fixedly connected with the output end of the stirring frame. By arranging the discharging assembly, the motor is started to drive the half gear to rotate, so that the impact rod impacts the discharging pipe to generate vibration, discharging is facilitated, and meanwhile the discharging pipe is reset through the spring.

Description

Technical Field

[0001] The utility model relates to the technical field of reaction kettles, in particular to a reaction kettle for preparing amlodipine besylate tablets. Background Art

[0002] Reactors are broadly understood as containers for physical or chemical reactions. Through the structural design and parameter configuration of the container, the heating, evaporation, cooling and low-speed mixing functions required by the process are realized. Reactors are widely used in petroleum, chemical, rubber, pesticides, dyes, medicine, and food. They are pressure vessels used to complete processes such as vulcanization, nitration, hydrogenation, hydrocarbonization, polymerization, and condensation.

[0003] Chinese patent document CN215312280U discloses a biochemical pharmaceutical reactor capable of automatic cleaning, comprising a box body, a partition is fixedly installed between the upper ends of the inner wall of the box body, a rotating tube is rotatably connected to the middle of the top of the partition, a gear ring is sleeved on the upper end of the rotating tube, and the top of the rotating tube is rotatably connected to a three-way pipe through a joint, one-way valves are arranged on the pipe walls at both ends above the three-way pipe, and one end of the three-way pipe on the upper left is connected to an air guide pipe, one end of the air guide pipe runs through the box body and is connected to an external air pump, and one end on the upper right is connected to a water inlet pipe, and the water inlet pipe is fixedly connected to a water pump, one end of the water inlet pipe is connected to an external water source, a motor is fixedly installed on the inner top wall of the box body, and a rotating shaft is fixedly installed on the output shaft of the motor. The utility model solves the problem that the existing reactor is not thoroughly cleaned after the stirring reaction, and there will be drug residues, which will affect the quality of the pharmaceutical when it is used for the next reaction. However, although the inner wall of the reactor can be cleaned after the preparation is completed, the stirring form is too single. During the preparation process, the drug raw materials will be stratified due to different densities. At the same time, after the preparation is completed, they are directly discharged through the discharge pipe, and there is a risk of blockage during the discharge process. Utility Model Content

[0004] The utility model aims to solve the problem that although the inner wall of the existing reaction kettle can be cleaned after the preparation is completed, the stirring form is too single, and the drug raw materials will be stratified due to the difference in density during the preparation process. At the same time, after the preparation is completed, it is directly discharged through a discharge pipe, and there is a risk of blockage during the discharge process. A reaction kettle for preparing amlodipine besylate tablets is proposed.

[0005] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a reactor for preparing amlodipine besylate tablets, comprising a reactor assembly, and a feeding assembly fixedly connected to the bottom surface of the reactor assembly, the reactor assembly comprising a reactor body, a feed inlet is arranged on the upper surface of the reactor body, a feeding pipe is connected to the lower end of the reactor body, a support leg is fixedly connected to the bottom surface of the reactor body, a stirring motor is installed on the top of the reactor body, a stirring frame is fixedly connected to the output end of the stirring motor, a support rod is fixedly connected to the outer surface of the stirring frame, a rotating blade is installed on the support rod, the feeding assembly comprises a connecting column fixedly connected to the bottom surface of the reactor body, one end of the connecting column is fixedly connected to a support plate, the upper surface of the support plate is fixedly connected to a motor, a half gear is fixedly connected to the output end of the motor, an impact rod is meshingly connected to the outer surface of the half gear, and a spring is sleeved on the outer surface of the impact rod.

[0006] Preferably, a cover is installed on the feed port, and a handle is fixedly connected to the upper surface of the cover;

[0007] Used to close the feed opening while facilitating opening the lid.

[0008] Preferably, a valve is installed on the feed pipe;

[0009] Used to open or close the feed pipe at any time.

[0010] Preferably, the stirring frame comprises a transmission shaft, a collar is fixedly connected to the outer surface of the transmission shaft, a stirring blade is fixedly connected to the outer surface of the collar, a connecting rod is fixedly connected to the outer surface of the transmission shaft, and a scraper is fixedly connected to one end of the connecting rod;

[0011] It is used to stir the amlodipine besylate tablets in the reaction kettle and clean the amlodipine besylate tablets attached to the inner wall of the reaction kettle.

[0012] Preferably, a mounting frame is fixedly connected to the upper surface of the support plate, and the impact rod is movably mounted on the mounting frame;

[0013] Used to install the impact rod on the support plate to facilitate its work.

[0014] Preferably, an impact head is fixedly connected to one end of the impact rod, a stopper is fixedly connected to the outer surface of the impact rod, a spring is elastically installed between the mounting frame and the stopper, and the impact head is a component made of rubber;

[0015] It is used to compress the spring and make the impact head have a certain buffering effect at the same time, so as to avoid it causing irreversible damage to the feeding tube.

[0016] Compared with the prior art, the utility model has the following beneficial effects:

[0017] 1. The utility model proposes a reaction kettle for preparing amlodipine besylate tablets. By setting a feeding assembly, a motor is started to drive a half gear to rotate so that an impact rod hits a feeding tube to vibrate, which is convenient for feeding and resets the tube by a spring.

[0018] 2. The utility model proposes a reactor for preparing amlodipine besylate tablets. By setting a reactor assembly, a stirring blade stirs the amlodipine besylate tablets in the reactor, while the amlodipine besylate tablets contact with the rotating blade to rotate on the support rod, so that the amlodipine besylate tablets in the reactor can not only rotate in one direction but also be stirred up and down, so that they are stirred more evenly. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the overall structure of a reaction kettle for preparing amlodipine besylate tablets proposed in the utility model;

[0020] Figure 2 This is a schematic diagram of the overall structure of a reactor assembly of a reactor for preparing amlodipine besylate tablets proposed in the utility model;

[0021] Figure 3 This is a schematic diagram of the overall structure of a feed feed assembly of a reaction kettle for preparing amlodipine besylate tablets proposed in the utility model;

[0022] Figure 4 This is a schematic diagram of the overall structure of a stirring frame of a reaction kettle for preparing amlodipine besylate tablets proposed in the utility model;

[0023] Figure 5 This is a schematic diagram of the overall structure of the rotating blades of a reaction kettle for preparing amlodipine besylate tablets proposed in the utility model;

[0024] Figure 6 This is a schematic diagram of the overall structure of an impact rod of a reaction kettle for preparing amlodipine besylate tablets proposed in the utility model;

[0025] Legend:

[0026] 1. Reactor assembly; 11. Reactor body; 12. Feed inlet; 121. Cover; 122. Handle; 13. Feed pipe; 131. Valve; 14. Support leg; 15. Stirring motor; 16. Stirring frame; 161. Drive shaft; 162. Ring; 163 Stirring blade; 164. Connecting rod; 165. Scraper; 17. Support rod; 18. Rotating blade; 2. Feeding assembly; 21. Connecting column; 22. Support plate; 221. Mounting frame; 23. Motor; 24. Half gear; 25. Impact rod; 251. Impact head; 252. Baffle; 26. Spring. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0028] In the description of the present utility model, it should be noted that the orientation or position relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside", etc. is based on the orientation or position relationship shown in the drawings, which is only for the convenience of describing the present utility model and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present utility model; the terms "first", "second", and "third" are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance. In addition, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0029] Reference Figure 1-6The utility model provides an embodiment: a reactor for preparing amlodipine besylate tablets, comprising a reactor assembly 1, and a feeding assembly 2 fixedly connected to the bottom surface of the reactor assembly 1, the reactor assembly 1 comprises a reactor body 11, and a feeding port 12 is arranged on the upper surface of the reactor body 11, so as to facilitate adding amlodipine besylate tablets into the reactor body 11 for reaction, a feeding pipe 13 is connected to the lower end of the reactor body 11, so as to facilitate discharging the reacted amlodipine besylate tablets from the reactor body 11, a supporting leg 14 is fixedly connected to the bottom surface of the reactor body 11, and supports the whole reactor device, a stirring motor 15 is installed on the top of the reactor body 11, and a stirring frame 16 is driven, and the stirring motor 15 is driven. The output end is fixedly connected with a stirring frame 16 to stir the amlodipine besylate tablets in the reactor body 11. The outer surface of the stirring frame 16 is fixedly connected with a support rod 17, and a rotating blade 18 is installed on the support rod 17 to disrupt the stirring direction in the reactor body 11 so that the stirring is more uniform. The unloading component 2 includes a connecting column 21 fixedly connected to the bottom surface of the reactor body 11, one end of the connecting column 21 is fixedly connected to a support plate 22, and the upper surface of the support plate 22 is fixedly connected to a motor 23 to drive a half gear 24. The output end of the motor 23 is fixedly connected with the half gear 24, and the outer surface of the half gear 24 is meshingly connected with a striking rod 25, and the outer surface of the striking rod 25 is sleeved with a spring 26 to reset the striking rod 25.

[0030] A cover 121 is installed on the feed port 12 to prevent the amlodipine besylate tablets in the reactor body 11 from splashing out of the feed port 12. A handle 122 is fixedly connected to the upper surface of the cover 121 to facilitate opening the cover 121. A valve 131 is installed on the feed pipe 13 to facilitate opening or closing the feed pipe 13. The stirring frame 16 includes a transmission shaft 161. A collar 162 is fixedly connected to the outer surface of the transmission shaft 161. A stirring blade 163 is fixedly connected to the outer surface of the collar 162. Specifically, a linear propeller blade is only a rough schematic diagram in the figure. The amlodipine besylate tablets in the reactor body 11 are stirred. The outer surface of the transmission shaft 161 is fixedly connected to the outer surface of the ring 162. A connecting rod 164 is fixedly connected to the surface, and a scraper 165 is fixedly connected to one end of the connecting rod 164 to clean up the amlodipine besylate tablets attached to the inner wall of the reactor body 11. A mounting frame 221 is fixedly connected to the upper surface of the support plate 22. The impact rod 25 is movably mounted on the mounting frame 221. The impact rod 25 is installed to a specified position. An impact head 251 is fixedly connected to one end of the impact rod 25, and a baffle 252 is fixedly connected to the outer surface of the impact rod 25. A spring 26 is elastically installed between the mounting frame 221 and the baffle 252. The spring 26 is compressed to reset the impact rod 25, and the impact head 251 is a component made of rubber.

[0031] Working principle: first, open the lid 121 through the handle 122, then add the amlodipine besylate tablets into the reactor body 11 from the feed port 12, start the stirring motor 15 to drive the stirring frame 16 to stir the amlodipine besylate tablets in the reactor body 11, and at the same time, the amlodipine besylate tablets contact the rotating blade 18 to make the rotating blade 18 rotate to disrupt the stirring direction of the stirring blade 163, so that the stirring is more thorough. After the stirring is completed, open the valve 131 to discharge the reacted amlodipine besylate tablets from the discharge pipe 13, and at the same time start the motor 23 to drive the half gear 24 to drive the impact rod 25 to move, and cooperate with the spring 26 to continuously impact the discharge pipe 13, so that the discharge pipe 13 vibrates to facilitate discharge.

[0032] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A reaction kettle for preparing amlodipine besylate tablets, comprising a reaction kettle component (1), and a feeder component (2) fixedly connected to the bottom surface of the reaction kettle component (1), characterized in that: The reactor assembly (1) comprises a reactor body (11), the upper surface of the reactor body (11) is provided with a feed inlet (12), the lower end of the reactor body (11) is connected to a feed pipe (13), the lower bottom surface of the reactor body (11) is fixedly connected to a support leg (14), the top of the reactor body (11) is provided with a stirring motor (15), the output end of the stirring motor (15) is fixedly connected to a stirring frame (16), the outer surface of the stirring frame (16) is fixedly connected to a support rod (17), and the support leg (14) is fixedly connected to the bottom surface of the reactor body (11). A rotating blade (18) is installed on the rod (17), and the material discharge assembly (2) comprises a connecting column (21) fixedly connected to the bottom surface of the reactor body (11), one end of the connecting column (21) is fixedly connected to a support plate (22), the upper surface of the support plate (22) is fixedly connected to a motor (23), the output end of the motor (23) is fixedly connected to a half gear (24), the outer surface of the half gear (24) is meshingly connected to a striking rod (25), and the outer surface of the striking rod (25) is sleeved with a spring (26).

2. A reaction kettle for preparing amlodipine besylate tablets according to claim 1, characterized in that: The feed port (12) is provided with a cover (121), and a handle (122) is fixedly connected to the upper surface of the cover (121).

3. A reaction kettle for preparing amlodipine besylate tablets according to claim 1, characterized in that: The feed pipe (13) is provided with a valve (131).

4. A reaction kettle for preparing amlodipine besylate tablets according to claim 1, characterized in that: The stirring frame (16) comprises a transmission shaft (161), a collar (162) is fixedly connected to the outer surface of the transmission shaft (161), a stirring blade (163) is fixedly connected to the outer surface of the collar (162), a connecting rod (164) is fixedly connected to the outer surface of the transmission shaft (161), and a scraper (165) is fixedly connected to one end of the connecting rod (164).

5. A reaction kettle for preparing amlodipine besylate tablets according to claim 1, characterized in that: The upper surface of the support plate (22) is fixedly connected with a mounting frame (221), and the impact rod (25) is movably mounted on the mounting frame (221).

6. The reaction kettle for preparing amlodipine besylate tablets according to claim 1, characterized in that: One end of the impact rod (25) is fixedly connected to an impact head (251), the outer surface of the impact rod (25) is fixedly connected to a stopper (252), the spring (26) is elastically installed between the mounting frame (221) and the stopper (252), and the impact head (251) is a component made of rubber.

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