Tweezers

Abstract

The utility model discloses a pair of tweezers. The tweezers comprise a plurality of tweezers handles and a plurality of clamping parts, the first ends of the forceps handles are fixedly connected together; the second ends of the forceps handles are in a separated state and are fixedly connected with one clamping part; the plurality of clamping parts are provided with accommodating cavities for clamping and / or accommodating tiny suspension culture tissues; and the opening ends of the multiple accommodating cavities of the multiple clamping parts are oppositely arranged. And a sieve hole part is arranged on the accommodating cavity. According to the utility model, the micro suspension culture tissue can be simply, conveniently and efficiently clamped and / or accommodated, the integrity of the micro suspension culture tissue structure can be prevented from being damaged when the micro suspension culture tissue is clamped, accommodated and / or transferred, and meanwhile, the structure is simple, and the use is convenient.

Description

Technical Field

[0001] The utility model belongs to the technical field of biomedicine, and in particular relates to a pair of tweezers. Background Art

[0002] Tweezers are a handheld tool commonly used in the field of biomedical research, used to pick up certain small items, such as tissue blocks and / or tiny experimental materials. Tweezers generally have two handles, the first ends of the two handles are fixedly connected, and the second ends are separated to form a clamping end. The clamping end of the tweezers has various shapes to meet the different use purposes of researchers.

[0003] Organoids are 3D cultures derived from human stem cells, organ-specific progenitor cells, and tumor tissues. They can mimic the structure and function of natural organs and accurately reflect the individual specificity and genetic background of tissues. At present, organoids are widely used in the field of biomedical research and are the hottest research model. Countries such as China and the United States have conducted a number of clinical trials, prospective observations, and randomized controlled trials based on organoids, hoping to provide more strategies for the treatment of diseases. At present, researchers have successfully cultivated a variety of organoid models, such as brain, lung, liver, colon, heart, and other organoids, as well as organoids of various cancer tissues, such as glioma, lung cancer, and kidney cancer. The diameter of most organoids is 50 to 300 μm (micrometers), while the diameter of brain organoids and glioma organoids can reach 4000 microns. Organoids are small and soft, mostly spherical, and some organoids are irregular in shape. When conducting scientific experiments on organoids, single or multiple organoid balls are usually transferred by clamping operations. For example, in immunohistochemistry experiments, organoids need to be embedded in OCT (a water-soluble mixture of polyethylene glycol and polyvinyl alcohol), and single or multiple organoids need to be clamped and the surface moisture of the organoids needs to be minimized. However, current experimental tools usually destroy the structural integrity of organoids when clamping and transferring them, and the operation process is complicated and inconvenient to use. Utility Model Content

[0004] The utility model aims to provide a pair of tweezers to solve the deficiencies in the prior art.

[0005] In order to solve the above technical problems, the utility model adopts the following technical solutions: a pair of tweezers, comprising: a plurality of tweezer handles and a plurality of clamping parts; wherein the first ends of the plurality of tweezer handles are fixedly connected together; the second ends of the plurality of tweezer handles are in a separated state and are all fixedly connected to one of the clamping parts; the plurality of clamping parts each have a accommodating cavity for clamping and / or accommodating micro-suspended culture tissues; the opening ends of the plurality of accommodating cavities of the plurality of clamping parts are arranged opposite to each other.

[0006] Furthermore, the number of the forceps handles is two, and the number of the clamping parts is two.

[0007] Furthermore, the accommodating cavity is configured to be hemispherical or semi-ellipsoidal.

[0008] Furthermore, when the accommodating cavity is in the hemispherical shape, the outer diameter of the accommodating cavity is 1000 to 5000 micrometers.

[0009] Furthermore, each of the clamping portions is connected to the second end of one of the forceps handles via a connecting portion, and an outer diameter of the connecting portion is smaller than an outer diameter of the accommodating cavity.

[0010] Furthermore, a sieve hole portion is provided on the accommodating cavity.

[0011] Furthermore, the sieve hole portion includes a plurality of sieve holes arranged at intervals.

[0012] Furthermore, the pore size of the sieve is 90 to 110 microns.

[0013] Furthermore, the pore size of the sieve is 100 microns.

[0014] Furthermore, the joints of the open ends of the plurality of accommodating cavities are all provided with smooth contact surfaces.

[0015] Furthermore, there is a certain gap between the second end of each of the tweezers handles and the axis of the tweezers so that the tweezers handles have a certain curvature.

[0016] Furthermore, a texture structure is arranged on the outer surface of each of the tweezers handles.

[0017] Furthermore, the texture structure includes a plurality of transverse lines arranged on the outer surface of the tweezers handle, and the plurality of transverse lines are perpendicular to the axis.

[0018] Furthermore, the accommodating cavity is a transparent cavity.

[0019] Furthermore, the inner surface of the accommodating cavity is smooth.

[0020] Furthermore, the wall thickness of the accommodating cavity is 0.2-0.4 mm.

[0021] Furthermore, the clamping portion is a low-adsorption clamping portion.

[0022] Compared with the prior art, the beneficial effects of the utility model are:

[0023] 1. The tweezers of the utility model are provided with a plurality of clamping parts with a containing cavity, which can simply and efficiently clamp and / or contain micro-suspension culture tissues, and can prevent the integrity of the micro-suspension culture tissue structure from being destroyed when clamping, containing and / or transferring the micro-suspension culture tissues. At the same time, the structure is simple and easy to use.

[0024] 2. The tweezers of the utility model have two handles and two clamping parts, which can improve the convenience of using the tweezers.

[0025] 3. The accommodating cavity of the tweezers of the utility model is configured to be hemispherical or semi-elliptical, which can further facilitate the tweezers to grasp and / or accommodate micro-suspended culture tissues.

[0026] 4. The accommodating cavity of the tweezers of the present invention is provided with a sieve hole portion, which can facilitate filtering the moisture on the surface of the micro-suspended culture tissue.

[0027] 5. The joints of the opening ends of the multiple accommodating cavities of the tweezers of the present invention are all provided with smooth contact surfaces, which can further prevent the integrity of the micro-suspension culture tissue structure from being damaged when clamping, accommodating and / or transferring the micro-suspension culture tissue.

[0028] 6. The tweezers of the utility model are provided with a connecting portion, which can facilitate the connection of the clamping portion and the tweezer handle, and facilitate the operation of the tweezer handle and the clamping portion, further improving the convenience of using the tweezers.

[0029] 7. There is a certain gap between the second end of the tweezers handle of the utility model and the axis of the tweezers, so that the tweezers handle has a certain curvature, which can achieve the purpose of reducing force.

[0030] 8. The outer surface of the handle of the tweezers of the utility model is provided with a texture structure, which is convenient for users to hold.

[0031] 9. The clamping part of the tweezers of the present invention is a low-adsorption clamping part, which can reduce the sticking between the clamped object and the clamping part and better maintain the structural integrity of the clamped object.

[0032] 10. The tweezers of the utility model have simple structure, are easy to use, have a wide range of applications, and are economical. BRIEF DESCRIPTION OF THE DRAWINGS

[0033] Figure 1 A schematic structural diagram of a specific embodiment of the tweezers of the utility model is shown;

[0034] Figure 2 A structural schematic diagram of another specific embodiment of the tweezers of the utility model is shown;

[0035] Figure 3The schematic structural diagram of another specific embodiment of the tweezers of the utility model is shown.

[0036] Among them, 1-tweezers handle; 11-first end; 12-second end; 2-clamping part; 21-accommodating cavity; 221-outer diameter; 22-opening end; 23-sieve hole part; 231-sieve hole; 24-smooth contact surface; 3-connecting part; 4-texture structure; 41-horizontal stripes. DETAILED DESCRIPTION

[0037] The utility model will be further described below in conjunction with the embodiments shown in the accompanying drawings.

[0038] Directional terms such as "inner", "outer", "axial", "lateral", etc. mentioned in the present invention are only used to refer to the drawings. Therefore, the directional terms used are used to illustrate and understand the present invention, but not to limit the present invention.

[0039] like Figures 1 to 3 As shown, the tweezers of the utility model include: a plurality of tweezer handles 1 and a plurality of clamping parts 2.

[0040] The first ends 11 of the plurality of forceps handles 1 are fixedly connected together. The second ends 12 of the plurality of forceps handles 1 are separated and fixedly connected to a clamping portion 2 .

[0041] The plurality of clamping parts 2 each have a receiving cavity 21 for clamping and / or receiving micro-suspended culture tissues (with a diameter greater than 100 micrometers). The opening ends 22 of the plurality of receiving cavities 21 of the plurality of clamping parts 2 are arranged opposite to each other.

[0042] Among them, since the multiple clamping parts 2 all have a accommodating cavity 21 for clamping and / or accommodating micro-suspension culture tissues, the multiple clamping parts 2 can be used to simply and efficiently clamp and / or accommodate micro-suspension culture tissues, and can prevent the integrity of the micro-suspension culture tissue structure from being destroyed when clamping, accommodating and / or transferring the micro-suspension culture tissues. At the same time, the structure is simple and easy to use.

[0043] In a specific embodiment, Figure 1 , Figure 2 As shown, there are two tweezers handles 1 and two clamping parts 2, which can further improve the convenience of using the tweezers.

[0044] In a specific embodiment, Figures 1 to 3 As shown, the accommodating cavity 21 is configured to be hemispherical or semi-elliptical, which can further facilitate the forceps to grasp and / or hold the micro-suspended culture tissue. For example, when the accommodating cavities 21 of the two grasping parts 2 are embraced, they are spherical.

[0045] In a specific embodiment, Figures 1 to 3As shown, when the accommodating cavity 21 is hemispherical, the outer diameter 221 of the accommodating cavity 21 is 1000-5000 microns, which can facilitate clamping and / or accommodating one or more micro-suspended culture tissues.

[0046] In a specific embodiment, Figures 1 to 3 As shown, each clamping portion 2 is connected to the second end 12 of a forceps handle 1 through a connecting portion 3. The outer diameter of the connecting portion 3 is smaller than the outer diameter 221 of the accommodating cavity 21. The connecting portion 3 can be used to easily connect the clamping portion 2 to the forceps handle 1, and to facilitate the operation of the forceps handle 1 and the clamping portion 2, further improving the convenience of using the tweezers.

[0047] In a specific embodiment, Figures 1 to 3 As shown, the clamping portion 2 is a low-adsorption clamping portion, which can reduce the adhesion between the clamped object and the clamping portion 2 and better maintain the structural integrity of the clamped object.

[0048] In a specific embodiment, Figures 1 to 3 As shown, the accommodating cavity 21 is provided with a sieve hole portion 23 penetrating the inner surface and the outer surface of the accommodating cavity 21, which can facilitate filtering the moisture on the surface of the micro-suspension culture.

[0049] In a specific embodiment, Figures 1 to 3 As shown, the sieve portion 23 includes a plurality of sieve holes 231 arranged at intervals, which can further facilitate filtering of moisture on the surface of the micro-suspension culture tissue.

[0050] In a specific embodiment, Figures 1 to 3 As shown, the pore size of the sieve hole 231 is 90 to 110 microns, which has a good effect of filtering moisture.

[0051] In a specific embodiment, Figures 1 to 3 As shown, the pore size of the sieve hole 231 is 100 microns, which has a better effect of filtering moisture.

[0052] In a specific embodiment, Figures 1 to 3 As shown, the joints of the open ends 22 of the multiple accommodating cavities 21 are all provided with smooth contact surfaces 24, which can further prevent the integrity of the micro-suspension culture tissue structure from being damaged when clamping, accommodating and / or transferring the micro-suspension culture tissue.

[0053] In a specific embodiment, Figure 1 , Figure 2 As shown, there is a certain gap between the second end 12 of each tweezers handle 1 and the axis of the tweezers 1 so that the tweezers handle 1 has a certain curvature, thereby achieving the purpose of reducing force.

[0054] In a specific embodiment, Figures 1 to 3As shown, a texture structure 4 is provided on the outer surface of each tweezers handle 1, which is convenient for the user to hold.

[0055] In a specific embodiment, Figures 1 to 3 As shown, the texture structure 4 includes a plurality of transverse lines 41 arranged on the outer surface of the tweezers handle 1, and the plurality of transverse lines 41 are perpendicular to the axis, which can further facilitate the user to hold the tweezers.

[0056] In a specific embodiment, Figures 1 to 3 As shown, the containing cavity 21 is a transparent cavity, which can facilitate observation of the state of the clamped and / or contained micro-suspended culture tissue.

[0057] In a specific embodiment, Figures 1 to 3 As shown, the inner surface of the receiving cavity 21 is smooth and the wall thickness is 0.2 to 0.4 mm. The smooth inner surface of the receiving cavity 21 can further prevent the integrity of the micro-suspension culture tissue structure from being damaged when clamping, accommodating and / or transferring the micro-suspension culture tissue. The wall thickness of the receiving cavity 21 is 0.2 to 0.4 mm, which can facilitate the clamping of the micro-suspension culture tissue. Preferably, the wall thickness of the receiving cavity 21 is 0.3 mm.

[0058] In a specific embodiment, the micro-suspension cultured tissue is an organoid, which can meet practical needs.

[0059] When the tweezers of the utility model are used, multiple accommodating cavities 21 can be used to simply and efficiently clamp and / or accommodate micro-suspension culture tissues, and can prevent the integrity of the micro-suspension culture tissue structure from being destroyed when clamping, accommodating and / or transferring the micro-suspension culture tissues. At the same time, the structure is simple and easy to use.

[0060] The protection scope of the present invention is not limited to the above-mentioned embodiments. Obviously, those skilled in the art can make various modifications and variations to the present invention without departing from the scope and spirit of the present invention. If these modifications and variations fall within the scope of the claims of the present invention and their equivalents, the intent of the present invention also includes these modifications and variations.

Claims

1. A pair of tweezers, characterized in that: include: A plurality of forceps handles (1) and a plurality of clamping parts (2); wherein: The first ends (11) of the plurality of tweezers handles (1) are fixedly connected together; the second ends (12) of the plurality of tweezers handles (1) are in a separated state and are all fixedly connected to one of the clamping portions (2); The plurality of clamping parts (2) each have a receiving cavity (21) for clamping and / or receiving micro-suspended culture tissues; the opening ends (22) of the plurality of receiving cavities (21) of the plurality of clamping parts (2) are arranged opposite to each other.

2. The tweezers according to claim 1, characterized in that: The number of the tweezers handles (1) is two, and the number of the clamping parts (2) is two.

3. The tweezers according to claim 2, characterized in that: The accommodating cavity (21) is configured to be hemispherical or semi-ellipsoidal.

4. The tweezers according to claim 3, characterized in that: When the accommodating cavity (21) is in the hemispherical shape, the outer diameter (221) of the accommodating cavity (21) is 1000 to 5000 micrometers.

5. The tweezers according to claim 4, characterized in that: Each of the clamping portions (2) is connected to the second end (12) of one of the forceps handles (1) via a connecting portion (3), and the outer diameter of the connecting portion (3) is smaller than the outer diameter (221) of the accommodating cavity (21).

6. The tweezers according to claim 1, characterized in that: The accommodating cavity (21) is provided with a sieve hole portion (23).

7. The tweezers according to claim 6, characterized in that: The sieve hole portion (23) comprises a plurality of sieve holes (231) arranged at intervals.

8. The tweezers according to claim 7, characterized in that: The pore size of the sieve hole (231) is 90 to 110 microns.

9. The tweezers according to claim 8, characterized in that: The pore size of the sieve hole (231) is 100 microns.

10. The tweezers according to claim 1, characterized in that: The joints of the open ends (22) of the plurality of accommodating cavities (21) are all provided with smooth contact surfaces (24).

11. The tweezers according to claim 2, characterized in that: There is a certain gap between the second end of each tweezer handle (1) and the axis of the tweezers, so that the tweezer handle (1) has a certain curvature.

12. The tweezers according to claim 11, characterized in that: A texture structure (4) is provided on the outer surface of each tweezer handle (1).

13. The tweezers according to claim 12, characterized in that: The texture structure (4) comprises a plurality of transverse lines (41) arranged on the outer surface of the tweezers handle (1), and the plurality of transverse lines (41) are all perpendicular to the axis.

14. The tweezers according to claim 1, characterized in that: The accommodating cavity (21) is a transparent cavity.

15. The tweezers according to claim 1, characterized in that: The inner surface of the accommodating cavity (21) is smooth, and the wall thickness of the accommodating cavity (21) is 0.2-0.4 mm.

16. The tweezers according to claim 1, characterized in that: The clamping portion (2) is a low-adsorption clamping portion.

Images