Collection bottle and stem cell freezing device

Abstract

The utility model provides a collection bottle and a stem cell freezing device, and belongs to the technical field of stem cell collection bottle freezing. The stem cell freezing device comprises a box body and a top cover arranged at the top end of the box body, drawing openings are formed in the two sides of the box body in pairs, and the stem cell freezing device further comprises a bottle body containing piece and a stem cell freezing piece. Each space is internally provided with a containing cylinder connected with the cross-shaped partition plate, and sealing covers used for covering the containing cylinders are evenly arranged on the top cover. The stem cell freezing part comprises a baffle and a drawer which enter and exit from the box body through the drawing opening, the baffle is located between the containing barrel and the drawer, and the box body is provided with a detachable connection part for fixing the baffle and the drawer. In the ice changing process, the stem cells in the collecting bottle can be cooled by ice blocks all the time, and the probability that the stem cells are influenced by temperature difference changes in the ice changing process is greatly reduced.

Description

Technical Field

[0001] The present application relates to the field of stem cell collection bottle freezing, and more specifically, to a collection bottle and a stem cell freezing device. Background Art

[0002] Stem cell collection is a method of collecting peripheral blood stem cells that is similar to the apheresis of blood components, that is, whole blood is collected through the peripheral blood of the upper arm, stem cells are extracted through a blood cell separator, collected into a collection bottle, and then the remaining blood components are returned to the body. Now, after the stem cells are collected into the collection bottle, they cannot be used because they can easily deteriorate at room temperature, so they need to be frozen immediately to avoid the deterioration of the stem cells.

[0003] Currently, low-temperature treatment is often performed by placing a stem cell collection bottle and ice cubes in the same container. However, when the room temperature is high, the ice cubes melt quickly and need to be constantly replaced. Each time the ice cubes are replaced, the stem cell collection bottle needs to be taken out and exposed to a high temperature environment before the ice cubes are replaced. The stem cells in the stem cell collection bottle can easily deteriorate due to the high temperature during the period of replacing the ice cubes.

[0004] In this regard, China's utility model patent application number is CN202320648256.8, which discloses a stem cell collection bottle and a freezing device thereof. The freezer is divided into a collection bottle placement chamber and an ice placement chamber located outside the collection bottle for placing ice cubes. At the same time, an ice replacement structure is designed to replace the ice cubes in the ice placement chamber without taking out the collection bottle, so that the stem cells in the stem cell collection bottle are not easily deteriorated due to high temperature.

[0005] However, in the process of implementing the technical solutions in the embodiments of the present application, the inventors of the present application found that the above technology has at least the following technical problems:

[0006] In the above scheme, when changing ice, all old ice cubes need to be taken out before new ice cubes can be put in. In this process, the probability of the temperature difference during the ice changing process affecting the stem cells cannot be reduced as much as possible. Utility Model Content

[0007] In order to make up for the above shortcomings, the present application provides a collection bottle and a stem cell freezing device, in which there are always ice cubes to cool the stem cells in the collection bottle during the ice changing process, which greatly reduces the probability of the temperature difference change during the ice changing process affecting the stem cells.

[0008] On the one hand, the present application provides a stem cell freezing device, including a box body and a top cover arranged on the top thereof, wherein both sides of the box body are provided with pull-out openings in pairs, and further including a bottle placement part and a stem cell freezing part:

[0009] The bottle placing part comprises a cross partition disposed in the box body, which can divide the interior of the box body into four spaces, each space is provided with a placing tube connected to the cross partition, and the top cover is evenly provided with a sealing cover for covering each placing tube respectively;

[0010] The stem cell freezing component comprises a baffle and a drawer that enter and exit the box body from the drawer opening, the baffle is located between the placement tube and the drawer, and the box body is provided with a connecting portion that detachably fixes the baffle and the drawer.

[0011] Preferably, the top cover is provided with an escape opening matched with the sealing cover, and a sealing rubber pad A is adhered to the outer peripheral side of the sealing cover and is movably attached to the opening of the placement tube.

[0012] Preferably, holes are evenly formed on the bottom wall of the placement cylinder.

[0013] Preferably, the side walls of the placement cylinder are connected to connecting rods fixed on the cross partition.

[0014] Preferably, the space above each baffle, located in the corresponding space divided by the cross partitions, and located outside the corresponding placement tube is an ice placement area.

[0015] Preferably, each of the ice cube placement areas is connected to a pipe on the top cover, and a cover body is screwed onto the top of each pipe.

[0016] Preferably, a sealing rubber pad B is bonded to the upper surface of the baffle plate and is movably attached to the upper inner wall of the drawer opening.

[0017] Preferably, the side wall of the baffle is connected with a sliding block, and the cross partition is provided with a sliding rail adapted to the sliding block.

[0018] Preferably, there are four connecting parts, including ears A, ears B and ears C, which are respectively fixed to the corresponding baffles, drawers and outer walls of the box body. The holes on the ears A, ears B and ears C are all threaded holes and are detachably fixed with locking screws.

[0019] On the other hand, the present application provides a collection bottle, which is arranged in the above-mentioned stem cell freezing device.

[0020] Beneficial effects: The present application provides a collection bottle and a stem cell freezing device. Ice cubes are placed in advance in a drawer and in an ice cube placement area surrounded by a baffle, a placement tube and a cross partition. Then, the sealing cover is opened to place the collection bottle in the placement tube for storage. The box body is divided into four spaces by the cross partition, each of which is designed with a placement tube. In this way, the number of collection bottles stored in the box body can be increased, and the use efficiency of the stem cell freezing device can be increased.

[0021] When the ice needs to be changed, first loosen the connection part that locks the drawer, pull out the drawer to dump the old ice cubes, and then return the drawer without new ice cubes to its original position, loosen the connection part that locks the baffle, pull out the baffle to make the ice cubes in the corresponding ice cube placement area fall into the drawer, and then re-install new ice cubes in the vacated ice cube placement area, then pull out the drawer, pour out the old ice cubes and put new ice cubes back to the original position, and finally use the connection part to re-lock the corresponding baffle and drawer. In this way, during the ice changing process, there are always ice cubes that do not leave the collection bottle, which greatly reduces the probability of the temperature difference during the ice changing process affecting the stem cells. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the technical solutions of the implementation methods of the present application, the drawings required for use in the implementation methods will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0023] Figure 1 It is a schematic diagram of the structure of a collection bottle and a stem cell freezing device provided in an embodiment of the present application;

[0024] Figure 2 A schematic diagram of the explosion structure of a collection bottle and a stem cell freezing device provided in an embodiment of the present application;

[0025] Figure 3 A schematic diagram of the structure of a box body provided in an embodiment of the present application after one side is cut open;

[0026] Figure 4 A schematic structural diagram of the positional relationship between the cross partition, the placement cylinder and the baffle provided in the embodiment of the present application;

[0027] Figure 5 A structural schematic diagram of the connection relationship between the cross partition and the drawer provided in the embodiment of the present application;

[0028] Figure 6 A schematic diagram of the box structure provided in an embodiment of the present application.

[0029] In the figure: 1-box body; 11-pull-out opening; 2-top cover; 21-avoidance opening; 22-pipeline; 23-cover body; 3-bottle body placement piece; 31-cross partition; 311-slide rail; 32-placing cylinder; 321-eyelet; 33-connecting rod; 34-sealing cover; 35-sealing rubber pad A; 4-stem cell freezing part; 41-baffle; 42-drawer; 43-slider; 44-ice cube placement area; 5-connecting part; 51-support ear C; 52-support ear A; 53-support ear B; 54-locking screw. DETAILED DESCRIPTION

[0030] The technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments.

[0031] See also Figure 1-Figure 6 The present application provides a stem cell freezing device, comprising a box body 1 and a top cover 2 arranged at the top thereof, characterized in that both sides of the box body 1 are provided with a pair of drawer openings 11, and also comprising a bottle placement part 3 and a stem cell freezing part 4:

[0032] The bottle placing member 3 includes a cross partition 31 arranged in the box body 1 to divide the interior thereof into four spaces, each space is provided with a placing tube 32 connected to the cross partition 31, and the top cover 2 is evenly provided with a sealing cover 34 for covering each placing tube 32 respectively;

[0033] The stem cell freezing component 4 includes a baffle 41 and a drawer 42 for entering and exiting the box body 1 from the drawer opening 11 . The baffle 41 is located between the placement tube 32 and the drawer 42 . The box body 1 is provided with a detachable connection portion 5 for fixing the baffle 41 and the drawer 42 .

[0034] In this embodiment, ice cubes are placed in the drawer 42 and in the ice cube placement area 44 surrounded by the baffle 41, the placement tube 32 and the cross partition 31 in advance, and then the sealing cover 34 is opened to place the collection bottle in the placement tube 32 for storage. The box body 1 is divided into four spaces by the cross partition 31, each of which is designed with a placement tube 32. In this way, the number of collection bottles stored in the box body 1 can be increased, and the use efficiency of the stem cell freezing device can be increased.

[0035] When it is necessary to change the ice, first loosen the connection part 5 that imprisons the drawer 42, pull out the drawer 42 to dump the old ice cubes, and then return the drawer 42 without new ice cubes to its original position, loosen the connection part 5 that imprisons the baffle 41, pull out the baffle 41 to make the ice cubes in the corresponding ice cube placement area 44 fall into the drawer 42, and then re-install the new ice cubes in the vacated ice cube placement area 44, then pull out the drawer 42, pour out the old ice cubes, and then load the new ice cubes and return them to their original position, and finally use the connection part 5 to re-lock the corresponding baffle 41 and drawer 42. In this way, during the ice changing process, there are always ice cubes that have not left the collection bottle, which greatly reduces the probability of the temperature difference during the ice changing process affecting the stem cells.

[0036] See also Figure 2 The top cover 2 is provided with an escape opening 21 adapted to the sealing cover 34, and a sealing rubber pad A35 is adhered to the outer peripheral side of the sealing cover 34 and is movably attached to the opening of the placement tube 32. Specifically, the design of the sealing rubber pad A35 can seal the joint between the sealing cover 34 and the placement tube 32, reducing the probability of cold air exposure.

[0037] See also Figure 4 , holes 321 are evenly provided on the bottom wall of the placement tube 32. Specifically, the design of the holes 321 can make the cold air generated by the ice cubes in the drawer 42 reach the collection bottle in the placement tube 32 faster.

[0038] See also Figure 4 The side walls of the placement tube 32 are connected with connecting rods 33 fixed on the cross partition 31. Specifically, the design of the connecting rod 33 can facilitate the fixing of the placement tube 32.

[0039] See also Figure 3 and Figure 5 The space above each baffle 41, located in the corresponding space divided by the cross partition 31, and located outside the corresponding placement tube 32 is an ice cube placement area 44. Specifically, there are four ice cube placement areas 44 in the present application. When one of the ice cube placement areas 44 is changing ice, the other three ice cube placement areas 44 can also radiate cold air toward the ice cube placement area 44 that is changing ice, so that the collection bottle that is changing ice can also enjoy the cooling temperature brought by the outer ice cube placement area 44, thereby improving the preservation effect of stem cells in the collection bottle.

[0040] See also Figure 2 and Figure 3 , each ice cube placement area 44 on the top cover 2 is connected to a pipe 22, and a cover 23 is screwed on the top of each pipe 22. Specifically, the outer wall of the pipe 22 and the inner circle of the cover 23 are provided with matching threads, and the port of the pipe 22 can be opened by unscrewing the cover 23, so that ice cubes can be easily put into the ice cube placement area 44.

[0041] See also Figure 5 and Figure 6 The upper surface of the baffle 41 is fixed with a sealing rubber pad B (not shown) that is movably attached to the inner wall of the drawer opening 11. Specifically, the design of the sealing rubber pad B can increase the sealing performance of the connection between the baffle 41 and the drawer opening 11, and reduce the probability of liquid seeping from the ice cube placement area 44 flowing out from the gap between the baffle 41 and the drawer opening 11.

[0042] See also Figure 5 The side wall of the baffle 41 is connected with a slider 43, and the cross partition 31 is provided with a slide rail 311 adapted to the slider 43. Specifically, the baffle 41 is conveniently slidably fixed on the cross partition 31 by the cooperation of the slider 43 and the slide rail 311.

[0043] See also Figure 3The connecting part 5 is provided with four parts, and includes a support ear A52, a support ear B53 and a support ear C51 respectively fixed to the corresponding outer wall of the baffle 41, the drawer 42 and the box body 1. The holes on the support ear A52, the support ear B53 and the support ear C51 are all threaded holes, and are detachably fixed with a locking screw 54. Specifically, the baffle 41, the drawer 42 and the box body 1 can be detachably fixed by tightening the locking screw 54 downward to make it cooperate with the support ear A52, the support ear B53 and the support ear C51.

[0044] On the other hand, the present application provides a collection bottle, which is arranged in the above-mentioned stem cell freezing device. It should also be noted that the collection bottle is placed inside the placement tube 32.

[0045] When using this application:

[0046] Ice cubes are placed in the drawer 42 and in the ice cube placement area 44 surrounded by the baffle 41, the placement tube 32 and the cross partition 31 in advance, and then the sealing cover 34 is opened to place the collection bottle in the placement tube 32 for storage. The box body 1 is divided into four spaces by the cross partition 31, each of which is designed with a placement tube 32, so that the number of collection bottles stored in the box body 1 can be increased, and the use efficiency of the stem cell freezing device can be increased;

[0047] When it is necessary to change the ice, the locking screw 54 is loosened to disengage it from the ear B53, so that the drawer 42 can be moved, the drawer 42 is pulled out to dump the old ice cubes, and then the drawer 42 without new ice cubes is returned to its original position, and the locking screw 54 is loosened again to disengage it from the ear A52, so that the baffle 41 can be moved, and the baffle 41 is pulled out to allow the ice cubes in the corresponding ice cube placement area 44 to fall into the drawer 42, and then the cover 23 is unscrewed, and the ice cube placement area 44 with the vacated space is reloaded with new ice cubes through the port of the pipe 22, and then the drawer 42 is pulled out, the old ice cubes are poured out and the new ice cubes are loaded and returned to the original position, and finally the locking screw 54 is tightened downward to be spirally fixed to the ears A52, B53 and C51. In this way, during the ice changing process, there are always ice cubes that have not fallen out of the collection bottle, which greatly reduces the probability of the temperature difference during the ice changing process affecting the stem cells.

[0048] It is obvious to those skilled in the art that the present application is not limited to the details of the exemplary embodiments described above, and that the present application can be implemented in other specific forms without departing from the spirit or essential features of the present application. Therefore, the embodiments should be regarded as exemplary and non-limiting in all respects, and the scope of the present application is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present application. Any reference numeral in a claim should not be regarded as limiting the claim to which it relates.

Claims

1. A stem cell freezing device, comprising a box body (1) and a top cover (2) arranged on the top of the box body, characterized in that: The box body (1) is provided with drawer openings (11) in pairs on both sides, and further comprises: The bottle placing member (3) comprises a cross partition (31) arranged in the box body (1) to divide the interior of the box body (1) into four spaces, each space is provided with a placing tube (32) connected to the cross partition (31), and the top cover (2) is evenly provided with a sealing cover (34) for covering each placing tube (32) respectively; The stem cell freezing device (4) comprises a baffle (41) and a drawer (42) for entering and exiting the box body (1) from the drawer opening (11); the baffle (41) is located between the placement tube (32) and the drawer (42); and a connecting portion (5) for detachably fixing the baffle (41) and the drawer (42) is provided on the box body (1).

2. The stem cell freezing device according to claim 1, characterized in that: The top cover (2) is provided with an escape opening (21) adapted to the sealing cover (34), and a sealing rubber pad A (35) is adhered to the outer peripheral side of the sealing cover (34) and is movably attached to the opening of the placement tube (32).

3. The stem cell freezing device according to claim 2, characterized in that: The bottom wall of the placement tube (32) is evenly provided with holes (321).

4. The stem cell freezing device according to claim 3, characterized in that: The side walls of the placement cylinder (32) are connected to connecting rods (33) fixed on the cross partition (31).

5. The stem cell freezing device according to claim 4, characterized in that: The space formed above each baffle (41), within the corresponding space divided by the cross partition (31), and outside the corresponding placement cylinder (32) is an ice cube placement area (44).

6. A stem cell freezing device according to claim 5, characterized in that: Each of the ice cube placement areas (44) on the top cover (2) is connected to a pipe (22), and a cover body (23) is screwed onto the top of each of the pipes (22).

7. The stem cell freezing device according to claim 1, characterized in that: The upper surface of the baffle (41) is bonded with a sealing rubber pad B which is movably attached to the upper inner wall of the drawer opening (11).

8. The stem cell freezing device according to claim 1, characterized in that: The side wall of the baffle (41) is connected to a sliding block (43), and the cross partition (31) is provided with a sliding rail (311) adapted to the sliding block (43).

9. The stem cell freezing device according to claim 1, characterized in that: The connecting parts (5) are provided with four, and include a support ear A (52), a support ear B (53) and a support ear C (51) respectively fixed to the corresponding outer walls of the baffle (41), the drawer (42) and the box body (1); the holes on the support ear A (52), the support ear B (53) and the support ear C (51) are all threaded holes, and a locking screw (54) is detachably fixed to them.

10. A collection bottle, characterized in that: The collection bottle is arranged in the stem cell freezing device according to any one of claims 1 to 9.

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