5-aminolevulinic acid separation and purification device

By designing a 5-aminolevulinic acid separation and purification device including a centrifugal cylinder, piston plate and liquid storage tank, the problem of easy adhesion of solid crystals is solved, efficient separation and collection is achieved, and production efficiency is improved.

CN222765816UActive Publication Date: 2025-04-18SU ZHOU YUE SHAN SHENG WU KE JI YOU XIAN GONG SI
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Patent Information

Application Number
CN202421333007.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-12
Publication Date
2025-04-18
Estimated Expiration
2034-06-12

AI Technical Summary

Technical Problem

During the preparation of 5-aminolevulinic acid, solid crystals tend to adhere to the inner wall of the centrifugal device, resulting in inconvenience in separation and collection.

Method used

A 5-aminolevulinic acid separation and purification device is designed, including a centrifugal cylinder, a piston plate and a liquid storage tank. Through the rotation of the centrifugal cylinder and the movement of the piston plate, the solution separates the solid crystals under the action of centrifugal force and enters the liquid storage tank through the screening holes to prevent the solid crystals from adhering to the inner wall of the centrifugal cylinder.

Benefits of technology

It effectively solves the problem of easy adhesion of solid crystals, realizes efficient separation and collection of 5-aminolevulinic acid, and improves production efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a 5-aminolevulinic acid separation and purification device which comprises a base, a controller is installed on the front face of the base, a rotation driving assembly is installed at the top end of the base, a centrifugal separation assembly is arranged above the base and comprises a centrifugal barrel, a piston plate is movably installed in the centrifugal barrel, and the piston plate is movably installed on the base. The outer wall of the piston plate is tightly attached to the inner wall of the centrifugal barrel, a hanging plate is installed at the top end of the piston plate, two vertical plates are symmetrically installed at the bottom end of the hanging plate and symmetrically arranged on the two sides of the centrifugal barrel, and transverse plates are fixedly installed at the bottom ends of the vertical plates; according to the centrifugal separation device, in the working process, the centrifugal cylinder is filled with a set solution, after the centrifugal cylinder rotates, the solution enters the liquid storage tank through the screening holes under the action of centrifugal force, solid crystals are left in the centrifugal cylinder, separation is convenient, and meanwhile the piston plate moves upwards while centrifugation is conducted; and the solution is continuously pushed upwards to the height flush with the screening holes, so that a large amount of solution can be conveniently separated.
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Description

Technical Field

[0001] The utility model belongs to the technical field of aminolevulinic acid production, in particular to a 5-aminolevulinic acid separation and purification device. Background Art

[0002] 5-aminolevulinic acid is a non-protein amino acid that plays a rate-limiting role in heme biosynthesis. In the preparation process of 5-aminolevulinic acid, the preparation solution needs to be cooled to form solid crystals, and then the solution is centrifuged through a centrifuge to separate the solution from the solid crystals, thereby completing the separation of 5-aminolevulinic acid. However, the following defects still exist:

[0003] During the centrifugation process, solid crystals tend to adhere to the inner wall of the centrifuge, making it inconvenient to collect the 5-aminolevulinic acid crystals. Utility Model Content

[0004] In view of the above situation, in order to overcome the defects of the prior art, the utility model provides a 5-aminolevulinic acid separation and purification device, which effectively solves the problem that solid crystals are easily adhered to the inner wall of the centrifugal device after centrifugal separation, making it inconvenient to collect.

[0005] To achieve the above object, the utility model provides the following technical solution: a 5-aminolevulinic acid separation and purification device, comprising a base, a controller is installed on the front of the base, a rotation drive assembly is installed on the top of the base, and a centrifugal separation assembly is provided above the base;

[0006] The centrifugal separation component includes a centrifugal cylinder, a piston plate is movably installed inside the centrifugal cylinder, the outer wall of the piston plate is in close contact with the inner wall of the centrifugal cylinder, a hanging plate is installed on the top of the piston plate, two vertical plates are symmetrically installed on the bottom of the hanging plate, the two vertical plates are symmetrically arranged on both sides of the centrifugal cylinder, a horizontal plate is fixedly installed on the bottom of the vertical plate, and slots are opened at equal angles on the outer wall of the centrifugal cylinder.

[0007] Preferably, two fixed plates are installed on both sides of the centrifugal cylinder, and the two fixed plates are respectively located on the upper and lower sides of the transverse plate, a guide rod is fixedly installed between the two fixed plates on one side, and the transverse plate is slidably connected to the guide rod, and an adjusting screw is rotatably installed between the two fixed plates on the other side, the adjusting screw is threadedly connected to the transverse plate, the top end of the adjusting screw is fixedly connected to the output shaft of the second motor, and the second motor is fixedly installed on the fixed plate.

[0008] Preferably, a liquid storage tank is provided inside the centrifuge cylinder, the liquid storage tank is coaxially sleeved on the outside of the inner cavity of the centrifuge cylinder, and screening holes are evenly provided on one side of the liquid storage tank close to the inner cavity of the centrifuge cylinder, and the screening holes are connected to the inner cavity of the centrifuge cylinder.

[0009] Preferably, a drainage groove is provided at the bottom end of the liquid storage tank, a drainage pipe is installed at the bottom end of the drainage groove, a plate groove is provided on the outside of the drainage groove, a partition is slidably installed inside the plate groove, the partition separates the drainage groove, a plate box is fixedly installed on one side of the centrifugal cylinder, the plate box is connected to the plate groove, springs are symmetrically installed on one side of the partition close to the plate box, and a pull rod is installed on one side of the partition close to the plate box.

[0010] Preferably, the rotating drive assembly includes a placement plate arranged above the base, the centrifuge cylinder is placed above the placement plate, guide rails are installed at equal angles on the outer side of the placement plate, a clamping block is slidably installed inside the guide rail, a clamping block is fixedly installed on the side of the clamping block close to the centrifuge cylinder, the clamping block is clamped in the slot, a clamping screw is threadedly installed on the guide rail, and the clamping screw is used to clamp the clamping block.

[0011] Preferably, the bottom end of the placement plate is coaxially fixedly connected to the output shaft of the first motor, and the first motor is fixedly installed inside the base.

[0012] Compared with the prior art, the beneficial effects of the utility model are:

[0013] During operation, the set solution is filled into the centrifuge cylinder. After the centrifuge cylinder rotates, under the action of centrifugal force, the solution enters the liquid storage tank through the sieve holes, while the solid crystals are left inside the centrifuge cylinder, which is convenient for separation. At the same time, the piston plate moves upward during centrifugation, continuously pushing the solution upward to the same height as the sieve holes, which is convenient for separating a large amount of solution.

[0014] During operation, the outer wall of the piston plate is in close contact with the inner wall of the centrifuge cylinder. On the one hand, when the solution is filled into the centrifuge cylinder, it is prevented from entering the space below the piston plate through the gap between the centrifuge cylinder and the piston plate. On the other hand, after separation, the piston plate moves upward to completely scrape out the solid crystals adhering to the inner wall of the centrifuge cylinder, making it convenient for separation and collection. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. They are used together with the embodiments of the present invention to explain the present invention and do not constitute a limitation to the present invention.

[0016] In the attached picture:

[0017] Figure 1 This is a schematic diagram of the structure of a 5-aminolevulinic acid separation and purification device of the utility model;

[0018] Figure 2 This is a schematic diagram of the structure of the rotary drive assembly of the utility model;

[0019] Figure 3 This is a schematic diagram of the placement plate structure of the utility model;

[0020] Figure 4 This is a schematic diagram of the structure of the centrifugal separation component of the utility model;

[0021] Figure 5 It is a schematic diagram of the hanging plate structure of the utility model.

[0022] In the figure: 1. base; 2. controller; 3. rotation drive assembly; 301. placement plate; 302. guide rail; 303. clamping block; 304. clamping block; 305. pressing screw; 306. first motor; 4. centrifugal separation assembly; 401. centrifugal cylinder; 402. clamping slot; 403. liquid storage tank; 404. screening hole; 405. drainage slot; 406. drainage pipe; 407. plate slot; 408. partition; 409. plate box; 410. spring; 411. pull rod; 412. piston plate; 413. hanging plate; 414. vertical plate; 415. horizontal plate; 416. fixed plate; 417. guide rod; 418. adjusting screw; 419. second motor. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments; based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0024] Embodiment 1, by Figure 1-5 The utility model relates to a 5-aminolevulinic acid separation and purification device, comprising a base 1, a controller 2 is installed on the front of the base 1, a rotation drive component 3 is installed on the top of the base 1, and a centrifugal separation component 4 is provided above the base 1;

[0025] The centrifugal separation assembly 4 includes a centrifugal cylinder 401, a piston plate 412 is movably installed inside the centrifugal cylinder 401, the outer wall of the piston plate 412 is in close contact with the inner wall of the centrifugal cylinder 401, a hanging plate 413 is installed on the top of the piston plate 412, and two vertical plates 414 are symmetrically installed at the bottom of the hanging plate 413. The two vertical plates 414 are symmetrically arranged on both sides of the centrifugal cylinder 401, and a horizontal plate 415 is fixedly installed at the bottom of the vertical plate 414. A card slot 402 is opened at an equal angle on the outer wall of the centrifugal cylinder 401, and two fixed plates 416 are installed on both sides of the centrifugal cylinder 401. The two fixed plates 416 are respectively located on the upper and lower sides of the horizontal plate 415, and the two fixed plates 416 on one side A guide rod 417 is fixedly installed between the two fixed plates 416 on the other side, and the cross plate 415 is slidably connected to the guide rod 417. An adjusting screw 418 is rotatably installed between the two fixed plates 416 on the other side. The adjusting screw 418 is threadedly connected to the cross plate 415. The top of the adjusting screw 418 is fixedly connected to the output shaft of the second motor 419. The second motor 419 is fixedly installed on the fixed plate 416. A liquid storage tank 403 is provided inside the centrifugal cylinder 401. The liquid storage tank 403 is coaxially sleeved on the outside of the inner cavity of the centrifugal cylinder 401. Screening holes 404 are evenly provided on one side of the liquid storage tank 403 close to the inner cavity of the centrifugal cylinder 401. The screening holes 404 are connected to the inner cavity of the centrifugal cylinder 401. A drainage groove 405 is provided at the bottom of the liquid storage tank 403, a drainage pipe 406 is installed at the bottom of the drainage groove 405, a plate groove 407 is provided on the outside of the drainage groove 405, a partition 408 is slidably installed inside the plate groove 407, and the partition 408 separates the drainage groove 405. A plate box 409 is fixedly installed on one side of the centrifugal cylinder 401, and the plate box 409 is connected to the plate groove 407. A spring 410 is symmetrically installed on one side of the partition 408 close to the plate box 409, and a pull rod 411 is installed on one side of the partition 408 close to the plate box 409. The solution is filled into the centrifugal cylinder 401. After the centrifugal cylinder 401 rotates, the solution passes through the sieve hole 404 under the action of centrifugal force. The liquid enters the liquid storage tank 403, while the solid crystals are retained in the centrifuge cylinder 401, which is convenient for separation. At the same time, the piston plate 412 moves upward during centrifugation, and the solution is continuously pushed upward to the same height as the sieve hole 404, which is convenient for separating a large amount of solution. The outer wall of the piston plate 412 is in close contact with the inner wall of the centrifuge cylinder 401. On the one hand, when the solution is filled into the centrifuge cylinder 401, it is prevented from entering the space below the piston plate 412 through the gap between the centrifuge cylinder 401 and the piston plate 412. On the other hand, after separation, the piston plate 412 moves upward to completely scrape out the solid crystals adhering to the inner wall of the centrifuge cylinder 401, which is convenient for separation and collection.

[0026] The rotating drive assembly 3 includes a placement plate 301 arranged above the base 1, and the centrifugal cylinder 401 is placed above the placement plate 301. A guide rail 302 is installed at an equal angle on the outer side of the placement plate 301, and a clamping block 303 is slidably installed inside the guide rail 302. A clamping block 304 is fixedly installed on the side of the clamping block 303 close to the centrifugal cylinder 401, and the clamping block 304 is clamped with the clamping groove 402. A clamping screw 305 is threadedly installed on the guide rail 302, and the clamping screw 305 is used to clamp the clamping block 303. The bottom end of the placement plate 301 is coaxially fixedly connected to the output shaft of the first motor 306, and the first motor 306 is fixedly installed inside the base 1.

[0027] Working principle: When working, first place the centrifuge cylinder 401 on the placement plate 301, screw each compression screw 305, push the clamping block 303 toward the centrifuge cylinder 401, so that the clamping block 304 is clamped into the clamping groove 402, and the centrifuge cylinder 401 is fixed. Then, the solution to be separated and purified is introduced into the centrifuge cylinder 401. There are 5-aminolevulinic acid solid particles crystallized by cooling in the solution. Since the outer wall of the piston plate 412 is in close contact with the inside of the centrifuge cylinder 401, the solution will not flow to the bottom of the piston plate 412;

[0028] The first motor 306 is turned on to rotate the placement plate 301, and the centrifugal cylinder 401 is driven to rotate, so that the solution is rotated and centrifuged inside the centrifugal cylinder 401. When the solution enters the centrifugal cylinder 401, the solution enters the liquid storage tank 403 through the sieve hole 404, while the solid crystals remain inside the centrifugal cylinder 401. At the same time, under the action of centrifugal force, the water adhering to the surface of the solid crystals is thrown out together, thereby improving the separation effect of 5-aminolevulinic acid;

[0029] While the solution is continuously thrown into the liquid storage tank 403, the second motor 419 is turned on to rotate the adjusting screw 418. Since the adjusting screw 418 is threadedly connected to the horizontal plate 415, the piston plate 412 is driven to move upward, and the solution is continuously pushed upward to the height of the sieve hole 404, so as to facilitate separation.

[0030] When the solid and liquid are completely separated, since the outer wall of the piston plate 412 is in close contact with the inner wall of the centrifugal cylinder 401, the solid crystals adhering to the inner wall of the centrifugal cylinder 401 are continuously scraped out during the upward movement of the piston plate 412, which is convenient for collection;

[0031] Finally, the first motor 306 is turned off, the partition 408 is pulled toward the inside of the plate box 409, and the separated solution is discharged from the drain pipe 406.

Claims

1. A 5-aminolevulinic acid separation and purification device, comprising a base (1), characterized in that: A controller (2) is installed on the front of the base (1), a rotation drive assembly (3) is installed on the top of the base (1), and a centrifugal separation assembly (4) is provided above the base (1); The centrifugal separation component (4) comprises a centrifugal cylinder (401), a piston plate (412) is movably installed inside the centrifugal cylinder (401), the outer wall of the piston plate (412) is in close contact with the inner wall of the centrifugal cylinder (401), a hanging plate (413) is installed on the top of the piston plate (412), two vertical plates (414) are symmetrically installed on the bottom of the hanging plate (413), the two vertical plates (414) are symmetrically arranged on both sides of the centrifugal cylinder (401), a horizontal plate (415) is fixedly installed on the bottom of the vertical plates (414), and a clamping groove (402) is opened at an equal angle on the outer wall of the centrifugal cylinder (401).

2. A 5-aminolevulinic acid separation and purification device according to claim 1, characterized in that: Two fixing plates (416) are installed on both sides of the centrifugal cylinder (401), and the two fixing plates (416) are respectively located on the upper and lower sides of the transverse plate (415), a guide rod (417) is fixedly installed between the two fixing plates (416) on one side, and the transverse plate (415) is slidably connected to the guide rod (417), and an adjusting screw (418) is rotatably installed between the two fixing plates (416) on the other side, and the adjusting screw (418) is threadedly connected to the transverse plate (415), and the top end of the adjusting screw (418) is fixedly connected to the output shaft of the second motor (419), and the second motor (419) is fixedly installed on the fixing plate (416).

3. A 5-aminolevulinic acid separation and purification device according to claim 1, characterized in that: The centrifugal cylinder (401) is provided with a liquid storage tank (403) inside, the liquid storage tank (403) is coaxially sleeved on the outside of the inner cavity of the centrifugal cylinder (401), and sieving holes (404) are evenly provided on one side of the liquid storage tank (403) close to the inner cavity of the centrifugal cylinder (401), and the sieving holes (404) are connected to the inner cavity of the centrifugal cylinder (401).

4. A 5-aminolevulinic acid separation and purification device according to claim 3, characterized in that: The bottom end of the liquid storage tank (403) is provided with a drainage tank (405), the bottom end of the drainage tank (405) is installed with a drainage pipe (406), the outer side of the drainage tank (405) is provided with a plate tank (407), the inner side of the plate tank (407) is slidably installed with a partition (408), the partition (408) separates the drainage tank (405), one side of the centrifugal cylinder (401) is fixedly installed with a plate box (409), the plate box (409) is connected with the plate tank (407), a spring (410) is symmetrically installed on the side of the partition (408) close to the plate box (409), and a pull rod (411) is installed on the side of the partition (408) close to the plate box (409).

5. A 5-aminolevulinic acid separation and purification device according to claim 1, characterized in that: The rotary drive assembly (3) comprises a placement plate (301) arranged above the base (1), the centrifugal cylinder (401) is placed above the placement plate (301), guide rails (302) are installed at equal angles on the outer side of the placement plate (301), a clamping block (303) is slidably installed inside the guide rail (302), a clamping block (304) is fixedly installed on one side of the clamping block (303) close to the centrifugal cylinder (401), the clamping block (304) is clamped with the clamping groove (402), and a clamping screw (305) is threadedly installed on the guide rail (302), and the clamping screw (305) is used to clamp the clamping block (303).

6. A 5-aminolevulinic acid separation and purification device according to claim 5, characterized in that: The bottom end of the placement plate (301) is coaxially fixedly connected to the output shaft of the first motor (306), and the first motor (306) is fixedly installed inside the base (1).