Mouse fixing support suitable for eye experiment operation mode

By designing a mouse fixing bracket combining a flexible face restraint plate and a U-shaped groove at the neck, the problem that the prior art cannot effectively fix the mouse's head and face is solved, and efficient operation of eye experiments and protection of experimental animals are achieved.

CN222787926UActive Publication Date: 2025-04-25EYE HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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Patent Information

Application Number
CN202420810419.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-18
Publication Date
2025-04-25
Estimated Expiration
2034-04-18

AI Technical Summary

Technical Problem

The existing murine fixing stents cannot effectively fix the mouse's head and face, resulting in inconvenient eye experiment operation, low experimental efficiency and damage to experimental animals.

Method used

A mouse fixing bracket including a head fixing device and a body fixing device is designed. The head fixing device adopts a combination of a face flexible restraint plate and a U-shaped groove to achieve stable fixation of the mouse's head and neck through the design of a flexible restraint belt and U-shaped groove.

Benefits of technology

Through the use of this fixed stent, the micromovement of the bones and muscles of the mouse neck can be effectively offset, the damage to the experimental animals can be reduced, the experimental efficiency can be improved, and the experimental preparation process can be simplified.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to a mouse fixing support suitable for an eye experiment operation mode, which comprises a head fixing device and a body fixing device, the head fixing device is installed on one side of the body fixing device in the length direction, a plurality of flexible restraint straps are arranged on the head fixing device and the body fixing device in pairs, and the flexible restraint straps are connected with the head fixing device and the body fixing device. The fixing devices are used for fixing the body, the head top and the nose top of a mouse respectively; the head fixing device is provided with a face flexible restraining plate, and the face flexible restraining plate is a plastic plate attached to the face of a mouse. The mouse fixing support has the advantages that the body and the head of a mouse are fixed through the mouse fixing support, the face flexible restraining plate enlarges the restraining area with the face of the mouse, and therefore the strength of micro motion of neck bones and muscles of the mouse is counteracted, and the blank that no head fixing device only has a body fixing device exists in the current market is filled up; and the injury to the experimental animal is reduced through the face flexible restraint plate.
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Description

Technical Field

[0001] The utility model relates to the technical field of mouse experimental auxiliary tools, in particular to a mouse fixing bracket suitable for an eye experimental operation mode. Background Art

[0002] According to market research and actual laboratory use, there are many types of fixed brackets for mouse experiments on the market, but there is no fixed bracket specifically used to fix the mouse face, for eye and periorbital modeling, physical therapy or drug administration experiments. At the same time, the existing mouse fixation products have the following characteristics: long experiment time, difficult to fix the eye experiment site, and weak physiological limit tolerance of experimental mice. Existing products are used to fix the body, but cannot fix the head and face of the mouse; when using existing products for eye experiments, the mouse head will struggle and move due to external stimulation, and the experiment is difficult to operate and cannot be carried out normally. It is obviously unrealistic to use artificial methods to fix the mouse's eyes for a long time in the laboratory. Usually, the mouse's neck bones and muscles are fixed with ropes to control the mouse's micro-movement, or the experimental operation is performed directly after anesthesia. These methods cause great damage to the experimental animals and also lead to deviations in the experimental results.

[0003] In recent years, with the increase in various intelligent video devices such as smart phones, smart glasses, smart helmets, and smart screens, the number of people with eye diseases has gradually increased, especially teenagers. This market demand has led to an upward trend in eye drug experiments. Therefore, there is an urgent need to design a mouse fixation bracket suitable for eye experiment operation modes to provide product guarantees for the normal, smooth and efficient conduct of experiments. Utility Model Content

[0004] The technical problem to be solved by the utility model is to provide a mouse fixing bracket suitable for eye experiment operation mode, which is mainly suitable for experiments on mice in eye experiment operation, and is used to fix the body and head of the mouse, exposing the eye medication site: the eye and the periorbital area, so as to facilitate the experimental operators to perform modeling, physical therapy or medication operations.

[0005] The utility model solves the above technical problems with the following technical solutions: A mouse fixing bracket suitable for eye experiment operation mode, comprising: a head fixing device and a body fixing device, wherein the head fixing device is installed on one side of the length direction of the body fixing device, and the head fixing device and the body fixing device are both provided with a plurality of flexible restraint belts in pairs, which are used to fix the body, the top of the head and the top of the nose of the mouse respectively;

[0006] The head fixing device is provided with a face flexible restraint plate, and the face flexible restraint plate is a plastic plate that fits the mouse's face.

[0007] The beneficial effects of the utility model are as follows: the body and head of the mouse are fixed by the mouse fixing bracket, and the face flexible constraint plate expands the constraint area with the mouse face, thereby offsetting the force of micro-movement of the mouse neck bones and muscles, filling the gap in the current market where there is no head fixing device but only body fixing devices; the face flexible constraint plate reduces damage to experimental animals, and the head fixing device can be used in combination with the mouse body fixing device without destroying the structure of the body fixing device itself. The use of the fixing bracket improves the experimental efficiency, and the head fixing device has an integrated structure, which is simple and easy to operate, saving a lot of experimental preparation time.

[0008] On the basis of the above technical solution, the present invention can also be improved as follows.

[0009] Furthermore, the body fixing device comprises: a body fixing body, a plurality of groups of the flexible restraining belts are arranged in pairs at intervals along the length direction of the body fixing body, and the flexible restraining belts are arranged on the upper end surface of the body fixing body.

[0010] The beneficial effect of adopting the above further solution is: the body of the mouse is fixed by the body fixing body and the flexible restraint belt, so as to prevent the movement of the mouse from affecting the experimental operation.

[0011] Furthermore, one side of the face flexible restraint plate in the length direction is arranged on the upper end surface of the body fixing body, and the other side of the face flexible restraint plate in the length direction extends out of the end portion of the body fixing body.

[0012] The beneficial effect of adopting the above further scheme is: the design of the flexible facial restraint plate extending out of the body fixing body makes it easy for the operator to directly operate the flexible facial restraint plate to fit the mouse's face, thereby fixing the mouse's face and improving the convenience of operation.

[0013] Furthermore, the head fixing device also includes: a neck U-shaped groove, which is arranged on the upper end surface of the body fixing body along the width direction of the body fixing body, and one side of the neck U-shaped groove in the width direction abuts against the side of the face flexible restraint plate.

[0014] The beneficial effect of adopting the above further scheme is: fixing the mouse neck by the U-shaped groove on the neck, compared with the existing method of fixing the mouse neck with a rope, resisting the force of the mouse neck bones and muscles, and preventing micro-movement of the mouse head; preventing micro-movement of the mouse head by the U-shaped groove on the neck can reduce the damage to the experimental animals in the experiment.

[0015] Furthermore, the neck U-shaped groove is provided with an inwardly concave U-shaped groove for supporting the neck of the mouse.

[0016] The beneficial effect of adopting the above further scheme is that the groove supports the neck of the experimental mouse, and the design of the U-shaped groove can fix the neck of the mouse and form a fulcrum to transmit the force applied to this part. During the transmission process, the resistance of the material and structure and the restraint force during wrapping offset the strength of the bones and muscles of the mouse neck.

[0017] Furthermore, the bottom of the U-shaped groove is arranged higher than the upper end surface of the body fixing body, so as to support the neck of the mouse.

[0018] The beneficial effect of adopting the above further solution is that the U-shaped groove has a supporting effect on the mouse neck, thereby improving the comfort of the experiment.

[0019] Furthermore, a flexible layer is provided on the inner wall of the U-shaped groove.

[0020] The beneficial effect of adopting the above further solution is that the provision of the flexible layer improves the comfort of the mice during the experiment, helps to reduce the stress response of the experimental mice, and ensures the accuracy of the experimental results.

[0021] Furthermore, the neck U-shaped groove and the face flexible restraint plate are arranged on the same central axis;

[0022] A support strip is also provided on the lower end surface of the face flexible restraint plate corresponding to the central axis, and the support strip extends from the end of the body fixing body to the side of the face flexible restraint plate away from the neck U-shaped groove.

[0023] The beneficial effects of adopting the above further scheme are: corresponding to the position of the center point of the U-shaped groove on the neck, the body fixing body and one end of the support bar are connected by screws or mortise and tenon joints to form a T-shape, and the T-shaped structure ensures that the head fixing device for the eye experiment is firmly connected; and the face movable flexible constraint plate is fixed on the support bar along the central axis, and the surface and the bar form a whole, and the leverage effect of the support bar offsets the bone and muscle strength of the mouse neck.

[0024] Further, the end of the face flexible constraint plate that is in contact with the neck U-shaped groove is defined as the wide end of the face flexible constraint plate, and both ends of the wide end extend in an arc trajectory in a direction away from the neck U-shaped groove and gradually accommodate at one end point.

[0025] The beneficial effects of adopting the above further scheme are: through the pressing action of human hands, the mouse's face can be wrapped according to the shape of the mouse's face, the force-bearing area can be expanded, and no damage to the mouse's face will be caused; the force-bearing area is increased, and most of the force of the mouse's neck bones and muscles is decomposed into the facial flexible constraint surface where the facial flexible constraint plate contacts the mouse's face.

[0026] Furthermore, two pairs of the flexible restraint belts are arranged in pairs on the flexible restraint plate for the face, and each pair of the flexible restraint belts are symmetrically arranged about the central axis of the flexible restraint plate for the face, and one pair of the flexible restraint belts is arranged on one side of the flexible restraint plate for the face close to the wide end, so as to fix the top position of the mouse's head;

[0027] Another pair of the flexible restraining belts is spaced apart from the wide end of the flexible facial restraining plate and is used to fix the nose position of the mouse.

[0028] The beneficial effect of adopting the above-mentioned further scheme is that the U-shaped groove fulcrum of the neck, the fixing points of the first group of flexible constraint strips and the fixing points of the second group of flexible constraint strips form a triangle, and the stabilizing effect of the triangle is used to ensure the stability of the wrapping prestress of the flexible constraint plate on the face, offset the force of the mouse's neck bones and muscles, and ensure that the mouse's head does not undergo micro-movement. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 This is a schematic diagram of the overall structure of an embodiment of the utility model;

[0030] Figure 2 The utility model is a top view of an embodiment.

[0031] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0032] 1. Head fixing device; 2. Body fixing device; 3. Flexible restraint belt; 11. Flexible restraint plate for face; 12. U-shaped groove for neck; 13. Support bar; 121. U-shaped groove; 21. Body fixing body. DETAILED DESCRIPTION

[0033] The principles and features of the present invention are described below in conjunction with the accompanying drawings. The examples given are only used to explain the present invention and are not used to limit the scope of the present invention.

[0034] like Figure 1-2 As shown, the utility model provides a mouse fixing bracket suitable for an eye experiment operation mode, comprising: a head fixing device 1 and a body fixing device 2, wherein the head fixing device 1 is installed on one side of the length direction of the body fixing device 2, and for long-term use, the head fixing device 1 and the body fixing device 2 can be fixed on a workbench by screws or the like, and for temporary use, the head fixing device 1 and the body fixing device 2 can be fixed by double-sided tape or the like, without further limitation herein.

[0035] In this embodiment, multiple flexible restraint belts 3 are arranged in pairs on the head fixing device 1 and the body fixing device 2, and the body, the top of the head and the top of the nose of the mouse are fixed by the flexible restraint belts 3. The problem that similar products cannot fix the movement of the mouse's head is solved, ensuring the smooth progress of eye experiment operations and the accuracy and repeatability of experimental results. Specifically, the flexible restraint belt 3 is made of flexible materials such as fiber or pure cotton. After the flexible materials are tied, they can be cross-fixed with metal clips, plastic clamps, etc., which is simple to operate and avoids tearing injuries to the mouse, ensuring that the mouse is emotionally stable during the test stage.

[0036] Specifically, a flexible facial restraint plate 11 is provided on the head fixing device 1. The flexible facial restraint plate 11 is a plastic plate that fits the mouse's face. After the mouse is placed on the mouse fixing bracket in a prone position, the mouse's body is fixed by the flexible restraint belt 3 on the body fixing device 2, and the flexible facial restraint plate 11 is pressed by hand to fit and cover the mouse's face. The flexible restraint belt 3 on the head fixing device 1 is used to fix the mouse's head. The force-bearing area of ​​the flexible facial restraint plate 11 and the mouse's face is increased. By decomposing the force, the force of the mouse's neck bones and muscles is resisted. The flexible material avoids tearing the mouse's hair, causing little harm to the mouse, thereby ensuring that the mouse is emotionally stable during the test phase.

[0037] This fixed bracket can be used for rats or mice in eye experiments. The materials of the fixed bracket are mainly wood, flexible materials such as rubber, chemical fiber and other lightweight materials, and no personal injury will be caused by the falling of the fixed bracket; the fixed bracket itself does not use electric devices and there is no electrical (for example: battery) fire risk; the device components have no sharp points and edges and will not scratch people or mice; the device itself has no prestress and there is no risk of physical impact due to loss of control of prestress.

[0038] The body and head of the mouse are fixed by the mouse fixing bracket, and the face flexible constraint plate 11 expands the constraint area with the mouse face, thereby offsetting the force of the mouse neck bone and muscle micro-movement, solving the problem that when fixing the mouse head micro-movement in the current laboratory, if the thread and rope are loosely fixed, the fixation effect cannot be achieved, if the fixation is tight, the mouse suffocates and dies, and if the mouse head micro-movement is artificially constrained, human resources are wasted and the experimental efficiency is reduced. It fills the gap in the current market that there is no head fixing device 1 but only body fixing device 2; because the current laboratory generally uses ropes to tighten the mouse neck to resist the force of the mouse neck bones and muscles, due to the long experiment time, tightening the mouse neck for a long time will cause damage to the experimental animal, and the face flexible constraint plate 11 reduces the damage to the experimental animal. Without destroying the structure of the body fixing device 2 itself, the head fixing device 1 can be used in combination with the mouse body fixing device 2. Due to the stress response of the mouse, the neck is not fixed with the rope, and the experimental preparation stage takes a long time. In addition, the artificial fixation of the mouse head causes an increase in labor costs. The use of this fixing bracket improves the experimental efficiency, and the head fixing device 1 has an integrated structure, which is simple and easy to operate, saving a lot of experimental preparation time.

[0039] like Figure 1-2 As shown, in a preferred embodiment, the body fixing device 2 includes: a body fixing body 21, and a plurality of groups of flexible restraint belts 3 are arranged in pairs at intervals along the length direction of the body fixing body 21, wherein the flexible restraint belts 3 are arranged on the upper end surface of the body fixing body 21. In this embodiment, the body fixing body 21 is made of lightweight materials such as wood, and is a rectangular parallelepiped as a whole. The pairs of flexible restraint belts 3 are respectively fixed to the upper end surface of the body fixing body 21 by screws. Specifically, in the actual experimental process, the number of flexible restraint belts 3 can be set as needed, and no limitation is made here. The body fixing body 21 and the flexible restraint belts 3 are used to fix the mouse body to prevent the movement of the mouse from affecting the experimental operation.

[0040] like Figure 1-2 As shown, one side of the face flexible restraint plate 11 in the length direction is arranged on the upper end surface of the body fixing body 21, and the other side of the face flexible restraint plate 11 in the length direction is arranged to extend out of the end of the body fixing body 21. The design of the face flexible restraint plate 11 extending out of the body fixing body 21 facilitates the operator to directly operate the face flexible restraint plate 11 to fit the mouse's face, thereby achieving fixation of the mouse's face, and improving the convenience of operation.

[0041] like Figure 1As shown, in a preferred embodiment, the head fixing device 1 also includes: a neck U-shaped groove 12, the neck U-shaped groove 12 is arranged along the width direction of the body fixing body 21, and the length of the neck U-shaped groove 12 is slightly larger than the width dimension of the body fixing body 21, the neck U-shaped groove 12 is arranged on the upper end surface of the body fixing body 21, and one side of the neck U-shaped groove 12 in the width direction abuts against the side surface of the face flexible constraint plate 11; in this embodiment, the neck of the mouse is fixed by the neck U-shaped groove 12, compared with the existing method of fixing the neck of the mouse with a rope, resisting the force of the bones and muscles of the mouse neck, and preventing micro-movement of the mouse head; preventing micro-movement of the mouse head by the neck U-shaped groove 12 can reduce the damage to the experimental animals in the experiment.

[0042] Specifically, an inwardly concave U-shaped groove 121 is provided on the neck U-shaped groove 12. When conducting experiments, the mouse adopts a prone position, and the mouse's neck is confined in the U-shaped groove 121. The U-shaped groove 121 supports the neck of the experimental mouse, and the design of the U-shaped groove 121 can fix the mouse's neck and form a fulcrum to transmit the force applied to this part. During the transmission process, the resistance of the material and structure and the restraint force during wrapping offset the strength of the mouse's neck bones and muscles.

[0043] In some feasible embodiments, the length dimension of the neck U-shaped groove 12 is set to 160mm and the height dimension is 4mm; the lateral opening dimension of the U-shaped groove 121 is 6mm and the longitudinal opening depth is 2mm. This dimension meets the daily experimental requirements of rats or mice, so that the U-shaped groove 121 can fit the neck of the mouse tightly during the experiment without causing compression or discomfort; it can be imagined that the size of the neck U-shaped groove 12 can be set according to the actual experimental requirements. At the same time, combined with the specific dimensions, it can be seen that the bottom end of the U-shaped groove 121 is higher than the upper end surface of the body fixing body 21, so that the U-shaped groove 121 has a supporting effect on the mouse neck, which improves the comfort of the experiment; at the same time, it protects the mouse's neck, and avoids tightening the mouse's neck when the restraining force is all concentrated on the neck when the rope is fixed, causing the mouse to suffocate and die, resulting in the failure of the experiment.

[0044] In the preferred solution, a flexible layer is also provided on the inner wall of the U-shaped groove 121, and the flexible layer fits the neck of the experimental mouse during the experiment. The flexible layer is made of flexible material, wherein the flexible material can be rubber or leather, etc., which is not limited here. The mouse neck is placed in the U-shaped groove 121 of the neck U-shaped support groove, and the inner wall of the U-shaped groove 121 is made of flexible materials such as leather or rubber to fix the mouse neck while protecting the neck from damage; the setting of the flexible layer improves the comfort of the mouse during the experiment, helps to reduce the stress response of the experimental mouse, and ensures the accuracy of the experimental results.

[0045] like Figure 1-2As shown, in a preferred embodiment, the neck U-shaped groove 12 and the face flexible constraint plate 11 are arranged on the same central axis; specifically, a support bar 13 is arranged at the central axis of the lower end surface of the face flexible constraint plate 11, and the support bar 13 extends from the end of the body fixing body 21 to the side of the face flexible constraint plate 11 away from the neck U-shaped groove 12, wherein the face flexible constraint plate 11 is bonded to the support bar 13 along the central axis with high-strength glue, and one end of the support bar 13 is connected to the end of the body fixing body 21 with screws or mortise and tenon joints corresponding to the center point of the neck U-shaped groove 12. The support bar 13 is made of wood material and is fixedly connected to the body fixing body 21 to form a T shape.

[0046] In the above scheme, corresponding to the position of the center point of the U-shaped groove 12 on the neck, the body fixing body 21 and one end of the support bar 13 are connected by screws or mortise and tenon joints to form a T-shape, and the T-shaped structure ensures that the eye experiment head fixing device 1 is firmly connected; and the face movable flexible constraint plate is fixed on the support bar 13 along the central axis, and the surface and the bar form a whole, and the leverage effect of the support bar 13 offsets the bone and muscle strength of the mouse neck.

[0047] like Figure 1-2 As shown, the end where the face flexible constraint plate 11 abuts against the neck U-shaped groove 12 is defined as the wide end of the face flexible constraint plate 11. The two ends of the wide end extend in an arc-shaped trajectory in the direction away from the neck U-shaped groove 12 and gradually accommodate at one end point. The specific shape of the face flexible constraint plate 11 is similar to half an ellipse. In some feasible embodiments, the overall size of the face flexible constraint plate 11 is set to: length * width * height = 100mm * 2mm * 2mm; in this embodiment, the face movable flexible constraint plate is also made of flexible materials, such as rubber or leather. Through the pressure of the human hand, it can wrap the mouse's face according to the shape of the mouse's face, expand the force-bearing area, and will not cause damage to the mouse's face; the force-bearing area is increased, and most of the force of the mouse's neck bones and muscles is decomposed to the face flexible constraint surface where the face flexible constraint plate 11 contacts the mouse's face by force decomposition.

[0048] In the above scheme, the mouse's face is wrapped with the flexible facial constraint plate 11. The supporting force and material strength of the support bar 13 are superimposed on the wrapping prestress of the flexible facial constraint plate 11. A lever effect is formed through the support bar 13. By decomposing the force, the force of the mouse's neck bones and muscles is resisted. The flexible material avoids tearing the mouse's hair, causing little harm to the mouse, thereby ensuring that the mouse is emotionally stable during the test phase.

[0049] like Figure 1-2As shown, in a preferred embodiment, two pairs of flexible restraint belts 3 are arranged in pairs on the flexible restraint plate 11 for face, that is, two groups of four flexible restraint belts 3, the pairs of flexible restraint belts 3 are symmetrically arranged about the central axis of the flexible restraint plate 11 for face, the two wings of the flexible restraint plate 11 for face are connected to the flexible restraint belts 3 by sewing, the first group of flexible restraint belts 3 are arranged on the upper end surface of the flexible restraint plate 11 for face, close to the wide end of the flexible restraint plate 11 for face, and are used to wrap the fan-shaped restraint plate for face, and are fixed to the top of the mouse's head by a plastic clamp or a metal frame during the experiment; the second group of restraint belts are arranged at intervals from the wide end of the flexible restraint plate 11 for face, and when specifically arranged, another pair of flexible restraint belts 3 are arranged at 1 / 2 of the distance from the wide end, and are used to wrap the fan-shaped restraint plate for face, and are fixed to the mouse's nose by a plastic clamp or a metal frame during the experiment.

[0050] In this embodiment, the head fixing device 1 adopts an integrated design. The mouse experiment head fixing device 1 is composed of a neck U-shaped groove 12, a face flexible constraint plate 11, a support bar 13 and two sets of flexible constraint belts 3. The above components are fixedly connected to each other to form a whole, so that no additional assembly is required during use.

[0051] In this embodiment, the two groups of constraint strips on the two wings of the facial flexible constraint plate 11 are made of flexible materials such as pure cotton or chemical fiber. The fulcrum of the neck U-shaped groove 12, the fixing points of the first group of flexible constraint strips and the fixing points of the second group of flexible constraint strips form a triangle. The stabilizing effect of the triangle is used to ensure the stability of the wrapping prestress of the facial flexible constraint plate 11, offset the force of the mouse's neck bones and muscles, and ensure that the mouse's head does not undergo micro-movement.

[0052] Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and cannot be understood as limitations of the present invention. Ordinary technicians in the field can change, modify, replace and modify the above embodiments within the scope of the present invention.

Claims

1. A rodent fixing bracket suitable for eye experiment operation mode, characterized in that: include: A head fixing device (1) and a body fixing device (2), wherein the head fixing device (1) is installed on one side of the body fixing device (2) in the length direction, and the head fixing device (1) and the body fixing device (2) are both provided with a plurality of flexible restraining belts (3) in pairs, which are used to fix the body, the top of the head and the top of the nose of the mouse respectively; The head fixing device (1) is provided with a face flexible restraining plate (11), and the face flexible restraining plate (11) is a plastic plate that fits the mouse's face.

2. A rodent fixing bracket suitable for eye experiment operation mode according to claim 1, characterized in that: The body fixing device (2) comprises: a body fixing body (21), a plurality of groups of flexible restraining belts (3) are arranged in pairs at intervals along the length direction of the body fixing body (21), and the flexible restraining belts (3) are arranged on the upper end surface of the body fixing body (21).

3. A rodent fixing bracket suitable for eye experiment operation mode according to claim 2, characterized in that: One side of the face flexible restraint plate (11) in the length direction is arranged on the upper end surface of the body fixing body (21), and the other side of the face flexible restraint plate (11) in the length direction extends out of the end of the body fixing body (21).

4. A rodent fixing bracket suitable for eye experiment operation mode according to claim 3, characterized in that: The head fixing device (1) further comprises: a neck U-shaped groove (12), wherein the neck U-shaped groove (12) is arranged on the upper end surface of the body fixing body (21) along the width direction of the body fixing body (21), and one side of the neck U-shaped groove (12) in the width direction abuts against the side surface of the face flexible restraint plate (11).

5. A rodent fixing bracket suitable for eye experiment operation mode according to claim 4, characterized in that: The neck U-shaped groove (12) is provided with an inwardly concave U-shaped groove (121) for supporting the neck of a mouse.

6. A rodent fixing bracket suitable for eye experiment operation mode according to claim 5, characterized in that: The bottom of the U-shaped groove (121) is arranged higher than the upper end surface of the body fixing body (21) and is used to support the neck of the mouse.

7. A rodent fixing bracket suitable for eye experiment operation mode according to claim 5 or 6, characterized in that: The inner wall of the U-shaped groove (121) is provided with a flexible layer.

8. A rodent fixing bracket suitable for eye experiment operation mode according to any one of claims 4 to 6, characterized in that: The neck U-shaped groove (12) and the face flexible restraining plate (11) are arranged on the same central axis; A support strip (13) is also provided on the lower end surface of the face flexible restraint plate (11) corresponding to the central axis, and the support strip (13) extends from the end of the body fixing body (21) to the side of the face flexible restraint plate (11) away from the neck U-shaped groove (12).

9. A rodent fixing bracket suitable for eye experiment operation mode according to any one of claims 4 to 6, characterized in that: The end of the face flexible restraint plate (11) that is in contact with the neck U-shaped groove (12) is defined as the wide end of the face flexible restraint plate (11), and both ends of the wide end extend in an arc-shaped trajectory in a direction away from the neck U-shaped groove (12) and are gradually accommodated at one end point.

10. A rodent fixing bracket suitable for eye experiment operation mode according to claim 9, characterized in that: Two pairs of the flexible restraint belts (3) are arranged in pairs on the flexible restraint plate (11) on the face, and each pair of the flexible restraint belts (3) are symmetrically arranged about the central axis of the flexible restraint plate (11) on the face, and one pair of the flexible restraint belts (3) is arranged on one side of the flexible restraint plate (11) on the face close to the wide end, and is used to fix the top position of the mouse's head; Another pair of the flexible restraining belts (3) are spaced apart from the wide end of the flexible facial restraining plate (11) to fix the position of the mouse's nose.