Liquid taking and adding device

By designing a liquid extraction and adding device including sample needles, reagent needles, drive components and cleaning tables, the problems of inaccurate, inclined and bent needles in the existing devices are solved, precise cleaning is achieved, and the safety and service life of the equipment are improved.

CN222812848UActive Publication Date: 2025-04-29BEIJING HUMAN INTELLIGENT MFG TECH CO LTD
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Patent Information

Application Number
CN202421150854.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-24
Publication Date
2025-04-29
Estimated Expiration
2034-05-24

AI Technical Summary

Technical Problem

In the long-term use or unexpected situations of existing liquid extraction and liquid addition devices, the sample needle and reagent needle may have problems such as inaccurate position, tilt, and bend, resulting in incomplete cleaning, equipment damage and use effects.

Method used

A liquid withdrawal and liquid addition device including a sample needle, a reagent needle, a first drive assembly, a second drive assembly and a cleaning table are designed. By driving the first drive assembly and the second drive assembly, the sample needle and the reagent needle move in the X, Y, Z directions, and the suction pump operates to sample and add liquid. Calibration elements, cleaning holes, inlet holes and outlet holes are installed on the cleaning table. The needle is calibrated through the calibration elements to ensure accurate cleaning.

Benefits of technology

The precise cleaning of sample needles and reagent needles is achieved, avoiding equipment damage and use effects due to inaccurate position, inclination and bending, and improving the safety, reliability and service life of the equipment.

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Patent Text Reader

Abstract

The utility model discloses a liquid taking and adding device. The device comprises a sample needle; the first driving assembly drives the sample needle to move in the X direction, the Y direction and the Z direction respectively; the sample needle and the reagent needle are respectively connected with the suction pump through pipelines; the second driving assembly drives the sample needle to move in the X direction, the Y direction and the Z direction respectively; the cleaning table is provided with a calibration element, a cleaning hole, a liquid inlet hole and a liquid outlet hole, the liquid inlet hole and the liquid outlet hole are communicated with the cleaning hole, and the calibration element is used for calibrating the sample needle or the reagent needle. The device is simple in structure and convenient to operate, the sample needle or the reagent needle is calibrated through the calibration element, it can be guaranteed that the sample needle and the reagent needle are accurately inserted into the cleaning hole to be cleaned, equipment damage, influence on equipment use and the like caused by inaccurate position, inclination, bending and the like of the sample needle or the reagent needle are avoided, safety and reliability are high, and practicability is high. And the cost is reduced.
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Description

Technical Field

[0001] The present application relates to medical testing equipment, and in particular to a liquid collection and addition device. Background Art

[0002] Immunoassay is a type of medical test, and common equipment includes chemiluminescence immunoassay analyzers, flow fluorescence immunoassay analyzers, etc. At present, in immunoassay analyzers such as chemiluminescence detection, a liquid collection and addition device is required to add samples and reagents to the reaction cup by moving, and the sample needle and reagent needle of the liquid collection and addition device need to be cleaned. However, the existing liquid collection and addition device may cause the sample needle and reagent needle to be inaccurately positioned, even tilted, bent, etc. due to long-term use or unexpected circumstances, which is not conducive to cleaning, damages the equipment, affects the use of the equipment, etc., and the equipment structure is generally more complicated and the cost is higher. Utility Model Content

[0003] The purpose of this application is to provide a liquid taking and adding device with high safety and reliability.

[0004] In order to solve at least one of the above technical problems, the technical solution of the present application is as follows:

[0005] A liquid taking and adding device provided according to an embodiment of the present application includes: a sample needle, which is arranged in a vertical direction; a first driving component, which drives the sample needle to move in an X direction, a Y direction, and a Z direction respectively; a reagent needle, which is arranged in a vertical direction, and the sample needle and the reagent needle are respectively connected to a suction pump through pipelines; a second driving component, which drives the sample needle to move in an X direction, a Y direction, and a Z direction respectively; a cleaning table, which is located below the sample needle and the reagent needle, and is provided with a calibration element, a cleaning hole, and a liquid inlet hole and a liquid outlet hole respectively connected to the cleaning hole, the liquid inlet hole and the liquid outlet hole are used for the entry and exit of the cleaning liquid, the calibration element is used to calibrate the sample needle or the reagent needle, the cleaning hole is arranged in a vertical direction, the liquid inlet hole is located at the upper end of the cleaning hole, and the liquid outlet hole is located at the lower end of the cleaning hole.

[0006] In a possible implementation of the above embodiment, the first drive assembly and the second drive assembly are mounted on the fixing plate and are located below the fixing plate.

[0007] In a possible implementation of the above embodiment, a control component that cooperates with the first drive component and the second drive component respectively is disposed on the fixed plate, and the control component is located above the fixed plate.

[0008] In a possible implementation of the above embodiment, the first driving assembly includes: a first driving member, the first driving member is mounted on the first connecting plate, the upper end of the sample needle is mounted on the connecting seat, the first driving member is connected to the connecting seat, and the first driving member drives the connecting seat and the sample needle to move along the Z direction; a second driving member, the second driving member is mounted on the second connecting plate, the second driving member is connected to the first connecting plate, and the second driving member drives the first connecting plate and the first driving member to move along the X direction; a third driving member, the third driving member is mounted on the fixed plate, the third driving member is connected to the second connecting plate, and the third driving member drives the second connecting plate and the second driving member to move along the Y direction.

[0009] In a possible implementation of the above embodiment, the third driving member is a motor with an encoder, the output shaft of the third driving member is connected to the second connecting plate through a transmission mechanism, a guide mechanism matching the second connecting plate is provided on the fixed plate, the guide mechanism is a linear slide rail arranged along the Y direction, and the transmission mechanism is a synchronous belt mechanism.

[0010] In a possible implementation of the above embodiment, a connector is disposed on the top of the sample needle, a protective shell matching the connector is disposed on the connection seat, and a first through hole for the pipeline to pass through is disposed on the protective shell.

[0011] In a possible implementation of the above embodiment, the calibration element is made of conductive metal material, a circular calibration hole is provided on the top of the calibration element, a first slot for accommodating the calibration element is provided on the cleaning table, and the top of the calibration element is higher than the top of the first slot.

[0012] In a possible implementation of the above embodiment, an upper cover is provided on the top of the cleaning station, a liquid inlet connector is provided on the upper cover, a second through hole for a sample needle or a reagent needle to pass through is provided on the liquid inlet connector, the second through hole is located above the cleaning hole and is connected to the cleaning hole, an extension portion extending to one side of the top of the cleaning station is provided on the upper cover, and a calibration element is provided on the extension portion.

[0013] In a possible implementation of the above embodiment, a second trough body matching with the liquid inlet joint is provided on the top of the cleaning table, the bottom of the liquid inlet joint is pressed against the bottom surface of the second trough body, a liquid inlet cavity is formed between the liquid inlet joint and the second trough body, the liquid inlet hole is connected with the liquid inlet cavity, a third through hole is provided on the liquid inlet joint, the third through hole is respectively connected with the liquid inlet cavity and the second through hole, the third through hole is inclined downward in the direction of the second through hole, the third through holes are uniformly distributed along the circumferential direction of the liquid inlet joint, and a sealing ring is provided between the liquid inlet joint and the second trough body.

[0014] In a possible implementation of the above embodiment, the liquid inlet hole is connected to a liquid inlet pipe, the liquid inlet pipe and the suction pump are respectively connected to the corresponding cleaning liquid supply device through pipelines, a liquid outlet joint and a third trough body matching the liquid outlet joint are provided at the bottom of the cleaning table, a liquid outlet cavity is formed between the liquid outlet joint and the third trough body, a fourth through hole, a fifth through hole and a second liquid outlet pipe are provided on the liquid outlet joint, the fourth through hole is located below the cleaning hole and is coaxial with the cleaning hole, the second liquid outlet pipe extends to the bottom of the cleaning table and is connected with the fourth through hole, the fifth through hole is respectively connected with the fourth through hole and the liquid outlet cavity, the fifth through hole is inclined downward in the direction of the liquid outlet cavity, the fifth through hole is a plurality of evenly distributed along the circumferential direction of the liquid outlet joint, and the liquid outlet is connected with the first liquid outlet pipe.

[0015] The above technical solution of the present application has at least one of the following beneficial effects:

[0016] According to the liquid taking and adding device of the present application, the first driving component drives the sample needle to move in the X direction, Y direction and Z direction respectively, and the suction pump works, so that the sample needle quantitatively takes out the sample and adds it to the corresponding reaction cup, and then the second driving component drives the sample needle to move in the X direction, Y direction and Z direction respectively, and the suction pump works, so that the reagent needle quantitatively takes out the reagent and adds it to the reaction cup to mix with the sample. When the sample needle needs to be cleaned, the first driving component drives the sample needle to move, and the sample needle moves to the position corresponding to the cleaning station. The sample needle is first calibrated by the calibration element to determine the position of the sample needle, whether the sample needle is bent or tilted, etc., and then the sample needle is inserted into the cleaning hole again, and the corresponding cleaning liquid enters the cleaning hole from the liquid inlet hole. The cleaning liquid in the cleaning hole cleans the sample needle and then flows out from the liquid outlet hole, thereby achieving the cleaning of the sample needle, and the cleaning of the reagent needle is similar. Therefore, the structure is simple and the operation is convenient. By calibrating the sample needle or reagent needle through the calibration element, it can ensure that the sample needle and the reagent needle are accurately inserted into the cleaning hole for cleaning, and avoid damage to the equipment and impact on the use of the equipment due to inaccurate position, tilt, bending, etc. of the sample needle or reagent needle. It has high safety and reliability, improves the accuracy and service life of the equipment, reduces costs, and is better used in immunoassay analyzers such as flow fluorescence and chemiluminescence.

[0017] Furthermore, in the present application, the first drive assembly and the second drive assembly are mounted on and below the fixed plate, thereby facilitating the installation of the liquid collection and addition device as a whole in the corresponding immunoassay analyzer, which is easy to operate.

[0018] Furthermore, in the present application, a control component is provided on the fixed plate and cooperates with the first drive component and the second drive component respectively. The control component is located above the fixed plate, so that installation, maintenance, adjustment and other operations are more convenient.

[0019] Further, in the present application, the first driving assembly includes a first driving member, a second driving member and a third driving member. The first driving member is installed on the first connecting plate, the upper end of the sample needle is installed on the connecting seat, the first driving member is connected to the connecting seat, the second driving member is installed on the second connecting plate, the second driving member is connected to the first connecting plate, and the third driving member is installed on the fixed plate. The first driving member drives the connecting seat and the sample needle to move along the Z direction, the second driving member drives the first connecting plate and the first driving member to move along the X direction, the third driving member is connected to the second connecting plate, and the third driving member drives the second connecting plate and the second driving member to move along the Y direction, so that the sample needle moves in the X direction, the Y direction and the Z direction respectively, ensuring that the sample needle can better take liquid, add liquid and clean.

[0020] Furthermore, in the present application, the third driving member is a motor with an encoder, which not only ensures the motion accuracy but also has a small size and a simplified structure.

[0021] Further, in the present application, the output shaft of the third driving member is connected to the second connecting plate through a transmission mechanism, a guide mechanism matching the second connecting plate is provided on the fixed plate, the guide mechanism is provided along the Y direction, and the third driving member drives the second connecting plate to reciprocate linearly along the guide mechanism, so that the movement is more stable and reliable. For example, the transmission mechanism is a synchronous belt mechanism, and the guide mechanism is a linear slide rail, which is more convenient to operate and has higher precision.

[0022] Furthermore, in the present application, a connector is provided at the top of the sample needle, and the sample needle is conveniently connected to the pipeline through the connector, making the operation more convenient. A protective shell matching the connector is also provided on the connection seat, and a first through hole for the pipeline to pass through is provided on the protective shell, thereby increasing safety and reliability.

[0023] Furthermore, in the present application, the calibration element is made of a conductive metal material, a circular calibration hole is provided on the top of the calibration element, and the sample needle or the reagent needle is inserted into the circular calibration hole of the calibration element for calibration to determine whether the sample needle or the reagent needle is inaccurately positioned, tilted, bent, etc. The structure is simple, safer and more reliable. A first trough body for accommodating the calibration element is also provided on the cleaning table, and the top of the calibration element is higher than the top of the first trough body, so that the structure is more compact and stable.

[0024] Furthermore, in the present application, an upper cover is provided on the top of the cleaning station, a liquid inlet connector is provided on the upper cover, a second through hole for a sample needle or a reagent needle to pass through is provided on the liquid inlet connector, the second through hole is located above the cleaning hole and is connected to the cleaning hole, and an extension portion extending to one side of the top of the cleaning station is provided on the upper cover, and a calibration element is provided on the extension portion, which not only makes the operation more convenient, but also reduces the volume of the cleaning station and occupies less space.

[0025] Furthermore, in the present application, a second trough body matched with the liquid inlet connector is provided on the top of the cleaning station, the bottom of the liquid inlet connector is pressed against the bottom surface of the second trough body, a liquid inlet cavity is formed between the liquid inlet connector and the second trough body, the liquid inlet hole is connected with the liquid inlet cavity, a third through hole is provided on the liquid inlet connector, the third through hole is connected with the liquid inlet cavity and the second through hole respectively, the third through hole is inclined downward in the direction of the second through hole, and the third through hole is evenly distributed along the circumferential direction of the liquid inlet connector, so that the cleaning liquid can enter the cleaning hole evenly from different directions, ensuring better cleaning of the sample needle or reagent needle, and the structure is more compact and stable. A sealing ring is also provided between the liquid inlet connector and the second trough body, so that the connection is tighter and leakage is avoided.

[0026] Further, in the present application, the liquid inlet is connected to a liquid inlet pipe, the liquid outlet is connected to a first liquid outlet pipe, the liquid inlet pipe and the suction pump are respectively connected to the corresponding cleaning liquid supply device through pipelines, so that the operation is more convenient, and the suction pump can also input the cleaning liquid into the sample needle or the reagent needle according to the demand to clean the inside of the sample needle or the reagent needle. The bottom of the cleaning table is also provided with a liquid outlet joint and a third trough body matched with the liquid outlet joint, a liquid outlet cavity is formed between the liquid outlet joint and the third trough body, and a fourth through hole, a fifth through hole and a second liquid outlet pipe are provided on the liquid outlet joint, the fourth through hole is located below the cleaning hole and is coaxial with the cleaning hole, the second liquid outlet pipe extends to the bottom of the cleaning table and is connected with the fourth through hole, the fifth through hole is respectively connected with the fourth through hole and the liquid outlet cavity, the fifth through hole is inclined downward in the direction of the liquid outlet cavity, and the fifth through hole is evenly distributed along the circumferential direction of the liquid outlet joint. The first liquid outlet pipe and the second liquid outlet pipe can be respectively connected to the corresponding cleaning liquid collection device through pipelines, so as to ensure that the cleaning liquid is better discharged, the operation is more convenient, and the structure is more compact and stable.

[0027] In addition, in the technical solution of the present application, unless otherwise specified, the technical solution can be implemented by adopting conventional means in the art. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] In order to more clearly illustrate the specific implementation methods of the present application or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0029] Figure 1 This is a schematic structural diagram of a liquid taking and adding device according to an embodiment of the present application;

[0030] Figure 2 This is a schematic diagram of the structure of a liquid taking and adding device according to an embodiment of the present application after removing the cleaning station;

[0031] Figure 3 This is a schematic diagram of the structure of a liquid taking and adding device according to an embodiment of the present application after removing the cleaning station;

[0032] Figure 4 A cross-sectional view of a sample needle and a connection seat according to an embodiment of the present application;

[0033] Figure 5 A schematic diagram of the partial structure of a liquid taking and adding device according to an embodiment of the present application;

[0034] Figure 6 This is a schematic diagram of the structure of a cleaning station according to an embodiment of the present application;

[0035] Figure 7 A cross-sectional view of a cleaning station according to an embodiment of the present application.

[0036] Description of the reference numerals in the accompanying drawings:

[0037] Sample needle 3100; connection seat 3110; connection head 3120; protection shell 3130; first through hole 3131;

[0038] First driving assembly 3200; first driving member 3210; first connecting plate 3220; second driving member 3230; second connecting plate 3240; third driving member 3250; transmission mechanism 3260;

[0039] Reagent needle 3300;

[0040] A second drive assembly 3400;

[0041] Cleaning table 3500; cleaning hole 3501; liquid inlet pipe 3502; first liquid outlet pipe 3503; first tank body 3504; second tank body 3505; third tank body 3506; calibration element 3510; circular calibration hole 3511; upper cover 3520; liquid inlet connector 3521; second through hole 3522; third through hole 3523; extension part 3524; liquid inlet cavity 3530; liquid outlet connector 3540; fourth through hole 3541; fifth through hole 3542; second liquid outlet pipe 3543; liquid outlet cavity 3550;

[0042] Fixed plate 3600; Guide mechanism 3610;

[0043] Control component 3700;

[0044] Suction pump 3800. DETAILED DESCRIPTION

[0045] In order to make the purpose, technical solutions and advantages of the present application clearer, the present application is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are part of the embodiments of the present application, rather than all of the embodiments, and are only used to explain the present application, and are not used to limit the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in the field without making creative work are within the scope of protection of the present application.

[0046] In the description of the present application, it should be noted that the terms "center", "upper", "lower", "left", "right", "front", "back", "vertical", "horizontal", "inside", "outside", "two ends", "both sides", "bottom", "top" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred elements must have a specific orientation or be constructed and operated in a specific orientation, and therefore cannot be understood as limitations on the present application. In addition, the terms "first", "second", "superior", "inferior", "primary", "secondary" and the like are only used for descriptive purposes and can be simply used to more clearly distinguish different components, but cannot be understood as indicating or implying relative importance.

[0047] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0048] In the drawings of the present application, an X direction, a Y direction, and a Z direction are given, wherein the Z direction is a vertical direction, the X direction and the Y direction are both horizontal directions, the X direction, the Y direction, and the Z direction are perpendicular to each other, the X direction can be equivalent to a horizontal horizontal direction, the Y direction can be equivalent to a horizontal vertical direction, and the "upper", "lower", etc. in the text are all referred to by the Z direction.

[0049] See also Figures 1 to 7 As shown, the liquid collection and addition device according to the present application is schematically shown, which is mainly used in immunoassay analyzers such as flow fluorescence and chemiluminescence to absorb samples and reagents and add samples and reagents into reaction cups.

[0050] According to an embodiment of the present application, a liquid collection and addition device is provided, including: a sample needle 3100, a first drive assembly 3200, a reagent needle 3300, a second drive assembly 3400 and a cleaning station 3500.

[0051] Among them, the sample needle 3100 and the reagent needle 3300 are respectively arranged in the vertical direction, the sample needle 3100 and the reagent needle 3300 are respectively connected to the suction pump 3800 through pipelines, the first driving component 3200 drives the sample needle 3100 to move in the X direction, Y direction and Z direction respectively, and the second driving component 3400 drives the reagent needle 3300 to move in the X direction, Y direction and Z direction respectively.

[0052] The cleaning station 3500 is located below the sample needle 3100 and the reagent needle 3300. The sample needle 3100 and the reagent needle 3300 can be moved to positions corresponding to the cleaning station 3500. The cleaning station 3500 is provided with a calibration element 3510, a cleaning hole 3501, and a liquid inlet hole and a liquid outlet hole respectively connected to the cleaning hole 3501. The liquid inlet hole and the liquid outlet hole are used for the inlet and outlet of the cleaning liquid. The calibration element 3510 is used to calibrate the sample needle 3100 or the reagent needle 3300. The cleaning hole 3501 is arranged in the vertical direction, the liquid inlet hole is located at the upper end of the cleaning hole 3501, and the liquid outlet hole is located at the lower end of the cleaning hole 3501. Among them, the liquid inlet hole and the liquid outlet hole are not shown in the drawings.

[0053] It should be noted that the liquid inlet is connected to the corresponding cleaning liquid supply device, and the liquid outlet is connected to the corresponding cleaning liquid collection device. The cleaning liquid can also be filtered and then returned to the cleaning liquid supply device for recycling. The liquid inlet and the liquid outlet can also be one, two or more. The cleaning table 3500 can be one, two or more. The sample needle 3100 and the reagent needle 3300 can correspond to the same cleaning table 3500, and the sample needle 3100 and the reagent needle 3300 can also correspond to a cleaning table 3500 respectively. The sample needle 3100 and the reagent needle 3300 can share a suction pump 3800, and the sample needle 3100 and the reagent needle 3300 can also correspond to a suction pump 3800 respectively. The suction pump 3800 can also be installed on other devices of the immunoassay analyzer.

[0054] The liquid collection and addition device of the present application is installed at the corresponding position of the immunoassay analyzer, and the first driving component 3200 drives the sample needle 3100 to move in the X direction, Y direction and Z direction respectively, and the suction pump 3800 works, so that the sample needle 3100 quantitatively removes the sample from the sample cup of the sample rack and adds the sample to the corresponding reaction cup, and then the second driving component 3400 drives the sample needle 3100 to move in the X direction, Y direction and Z direction respectively, and the suction pump 3800 works, so that the reagent needle 3300 quantitatively removes the reagent from the reagent bottle of the reagent storage device, and adds the reagent to the reaction cup to mix with the sample, thereby realizing liquid collection and addition of the sample and reagent. When it is necessary to clean the sample needle 3100, the first driving component 3200 drives the sample needle 3100 to move, and the sample needle 3100 moves to a position corresponding to the cleaning station 3500. The sample needle 3100 is first calibrated by the calibration element 3510 to determine the position of the sample needle 3100, whether the sample needle 3100 is bent or tilted, etc. If necessary, the sample needle 3100 can be manually adjusted and corrected, and then the sample needle 3100 is inserted into the cleaning hole 3501 again, and the corresponding cleaning liquid enters the cleaning hole 3501 from the liquid inlet hole. The cleaning liquid in the cleaning hole 3501 cleans the sample needle 3100 and then flows out from the liquid outlet hole, thereby cleaning the sample needle 3100. The cleaning of the reagent needle 3300 is similar, thereby ensuring that the sample needle 3100 and the reagent needle 3300 are accurately inserted into the cleaning hole 3501 for cleaning, thereby avoiding damage to the equipment and affecting the use of the equipment due to inaccurate position, tilt, bending, etc. of the sample needle 3100 and the reagent needle 3300.

[0055] The liquid collection and addition device according to the present application has a simple structure and is easy to operate. The sample needle 3100 or the reagent needle 3300 is calibrated by the calibration element 3510, which can ensure that the sample needle 3100 and the reagent needle 3300 are accurately inserted into the cleaning hole 3501 for cleaning, thereby avoiding damage to the equipment and affecting the use of the equipment due to inaccurate position, tilt, bending, etc. of the sample needle 3100 or the reagent needle 3300. It has high safety and reliability, improves the accuracy and service life of the equipment, reduces costs, and is better used in immunoassay analyzers such as flow fluorescence and chemiluminescence.

[0056] In some embodiments, the first drive assembly 3200 and the second drive assembly 3400 are mounted on a fixed plate 3600, and the first drive assembly 3200 and the second drive assembly 3400 are located below the fixed plate 3600. The fixed plate 3600 is used to connect with corresponding components of the immunoassay analyzer, that is, the sample needle 3100, the reagent needle 3300 and the cleaning station 3500 are all located below the fixed plate 3600. Therefore, it is convenient to install the liquid collection and addition device as a whole in the corresponding immunoassay analyzer, and the operation is convenient and fast.

[0057] In some embodiments, a control assembly 3700 that cooperates with the first drive assembly 3200 and the second drive assembly 3400 is disposed on the fixed plate 3600, and the control assembly 3700 is located above the fixed plate 3600. The control assembly 3700 generally includes electrical components such as a control circuit board and a control switch, which are not described in detail here. Therefore, by arranging the control assembly 3700 above the fixed plate 3600, installation, maintenance, adjustment and other operations are more convenient and quick.

[0058] In some embodiments, the first driving assembly 3200 includes: a first driving member 3210, a second driving member 3230, and a third driving member 3250. The first driving member 3210 is mounted on the first connecting plate 3220, the upper end of the sample needle 3100 is mounted on the connecting seat 3110, the first driving member 3210 is connected to the connecting seat 3110, the second driving member 3230 is mounted on the second connecting plate 3240, the second driving member 3230 is connected to the first connecting plate 3220, the third driving member 3250 is mounted on the fixing plate 3600, the third driving member 3250 is connected to the second connecting plate 3240, the first driving member 3210 drives the connecting seat 3110 and the sample needle 3100 to move in the Z direction, the second driving member 3230 drives the first connecting plate 3220 and the first driving member 3210 to move in the X direction, and the third driving member 3250 drives the second connecting plate 3240 and the second driving member 3230 to move in the Y direction.

[0059] During use, the first driving member 3210 drives the connecting seat 3110 and the sample needle 3100 to move along the Z direction, the second driving member 3230 drives the first connecting plate 3220 and the first driving member 3210 to move along the X direction, and the third driving member 3250 drives the second connecting plate 3240 and the second driving member 3230 to move along the Y direction, so that the sample needle 3100 can move along the X direction, the Y direction and the Z direction respectively, thereby ensuring that the sample needle 3100 can better perform liquid collection, liquid addition and cleaning.

[0060] Furthermore, the third driving member 3250 is a motor with an encoder. Thus, the use of a motor with an encoder can not only ensure the motion accuracy, but also has a small volume and a simplified structure.

[0061] Furthermore, the output shaft of the third driving member 3250 is connected to the second connecting plate 3240 through the transmission mechanism 3260, and the fixing plate 3600 is provided with a guide mechanism 3610 matched with the second connecting plate 3240, and the guide mechanism 3610 is arranged along the Y direction. Thus, the third driving member 3250 drives the second connecting plate 3240 to reciprocate linearly along the guide mechanism 3610, so that the movement is more stable and reliable.

[0062] Exemplarily, the transmission mechanism 3260 is a synchronous belt mechanism, the guide mechanism 3610 is a linear slide rail, the synchronous belt mechanism includes a driving wheel, a driven wheel and a synchronous belt, the output shaft of the motor with an encoder is connected to the driving wheel, the driven wheel is installed on the fixed plate 3600, the driving wheel and the driven wheel are connected by a synchronous belt, the synchronous belt is transmitted along the Y direction, the track of the linear slide rail is installed on the fixed plate 3600, and the second connecting plate 3240 is respectively connected to the synchronous belt and the slider of the linear slide rail. As a result, the operation is more convenient and the motion accuracy is higher.

[0063] In addition, the fixed plate 3600 may be provided with a tensioning wheel matched with the synchronous belt and a sensor for detecting the movement position, and the sensor may be a travel switch, a proximity switch, a photoelectric switch, an infrared sensor, etc. The suction pump 3800 may also be provided on the fixed plate 3600. Thus, the control is more convenient, safer, and more reliable.

[0064] Those skilled in the art will appreciate that the third drive member 3250 is not limited to a motor with an encoder, the transmission mechanism 3260 is not limited to a synchronous belt mechanism, and the guide mechanism 3610 is not limited to a linear slide rail. The third drive member 3250 may also be a servo motor, a cylinder, an oil cylinder, an electric cylinder, a linear module, etc., the transmission mechanism 3260 may also be a gear mechanism, a transmission chain mechanism, etc., the guide mechanism 3610 may also be a structure of a slider and a slide groove, etc. The first drive member 3210 and the second drive member 3230 may refer to the structure of the third drive member 3250 mentioned above, and the structures of the first drive assembly 3200 and the second drive assembly 3400 are substantially the same and will not be described in detail here.

[0065] In some embodiments, a connector 3120 is disposed at the top of the sample needle 3100. Thus, the sample needle 3100 is conveniently connected to a pipeline through the connector 3120, and the operation is more convenient.

[0066] Furthermore, the connection base 3110 is also provided with a protective shell 3130 that matches the connector 3120, and the protective shell 3130 is provided with a first through hole 3131 for the pipeline to pass through. In other words, the connector 3120 is located in the protective shell 3130, and the corresponding pipeline passes through the first through hole 3131 and is connected to the connector 3120 in the protective shell 3130, so that the safety and reliability are higher. It should be noted that the structure of the sample needle 3100 is basically the same as that of the reagent needle 3300, and will not be described in detail here.

[0067] In some embodiments, the calibration element 3510 is a conductive metal material, such as stainless steel, copper, semiconductor material, etc., and a circular calibration hole 3511 is provided on the top of the calibration element 3510. Among them, the circular calibration hole 3511 can be a through hole or a blind hole, and the calibration hole can also be other suitable shapes in the prior art. Thus, the sample needle 3100 or the reagent needle 3300 is inserted into the circular calibration hole 3511 of the calibration element 3510 for calibration, and it is determined whether the sample needle 3100 or the reagent needle 3300 is inaccurately positioned, tilted, bent, etc. When necessary, the sample needle 3100 can be manually adjusted and corrected to ensure that the sample needle 3100 and the reagent needle 3300 are accurately inserted into the cleaning hole 3501 for cleaning, so as to avoid damage to the equipment and influence on the use of the equipment due to inaccurate position, tilt, bending, etc. of the sample needle 3100 or the reagent needle 3300, and the structure is simple, safer and more reliable.

[0068] Furthermore, the cleaning station 3500 is provided with a first slot 3504 for accommodating the calibration element 3510, and the top of the calibration element 3510 is higher than the top of the first slot 3504. Thus, the calibration element 3510 is arranged in the first slot 3504, and the structure is more compact and stable, and the top of the calibration element 3510 is higher than the top of the first slot 3504, and the calibration of the sample needle 3100 and the reagent needle 3300 will not be affected.

[0069] In some embodiments, a top cover 3520 is provided on the top of the cleaning station 3500, a liquid inlet connector 3521 is provided on the top cover 3520, a second through hole 3522 for the sample needle 3100 or the reagent needle 3300 to pass through is provided on the liquid inlet connector 3521, the second through hole 3522 is located above the cleaning hole 3501 and communicates with the cleaning hole 3501, and a protrusion 3524 extending to one side of the top of the cleaning station 3500 is also provided on the top cover 3520, and the calibration element 3510 is provided on the protrusion 3524. As a result, not only the operation is more convenient and the structure is more stable, but also the volume of the cleaning station 3500 is reduced, and the occupied space is smaller.

[0070] In some embodiments, a second trough 3505 matching with the liquid inlet joint 3521 is provided on the top of the cleaning table 3500, the bottom of the liquid inlet joint 3521 is pressed against the bottom surface of the second trough 3505, a liquid inlet cavity 3530 is formed between the liquid inlet joint 3521 and the second trough 3505, the liquid inlet hole is connected with the liquid inlet cavity 3530, a third through hole 3523 is provided on the liquid inlet joint 3521, the third through hole 3523 is connected with the liquid inlet cavity 3530 and the second through hole 3522 respectively, the third through hole 3523 is inclined downward in the direction of the second through hole 3522, and the third through hole 3523 is uniformly distributed along the circumferential direction of the liquid inlet joint 3521. A sealing ring is provided between the liquid inlet joint 3521 and the second trough 3505. The liquid inlet joint 3521 and the upper cover 3520 can be integrally formed, and the sealing ring is not shown.

[0071] When the sample needle 3100 or the reagent needle 3300 is inserted into the cleaning hole 3501 for cleaning, the cleaning liquid enters the liquid inlet cavity 3530 from the liquid inlet hole, and the cleaning liquid in the liquid inlet cavity 3530 then evenly enters the second through hole 3522 through the third through holes 3523 in different directions. The third through holes 3523 are inclined to facilitate the cleaning liquid to flow into the second through hole 3522 more smoothly, so that the cleaning liquid can evenly enter the cleaning hole 3501 from different directions, ensuring better cleaning of the sample needle 3100 or the reagent needle 3300, better cleaning effect, and a more compact and stable structure.

[0072] In some embodiments, the liquid inlet is connected to a liquid inlet pipe 3502, the liquid outlet is connected to a first liquid outlet pipe 3503, and the liquid inlet pipe 3502 and the suction pump 3800 are respectively connected to the corresponding cleaning liquid supply device through pipelines. When the sample needle 3100 or the reagent needle 3300 is inserted into the cleaning hole 3501 for cleaning, the cleaning liquid entering the cleaning hole 3501 from the liquid inlet cleans the outside of the sample needle 3100 or the reagent needle 3300, and at the same time, the suction pump 3800 extracts the cleaning liquid from the cleaning liquid supply device and inputs it into the sample needle 3100 or the reagent needle 3300, and also cleans the inside of the sample needle 3100 or the reagent needle 3300, so that the operation is more convenient, the cleaning is more comprehensive and thorough, and the effect is better.

[0073] In some embodiments, a liquid outlet joint 3540 and a third trough body 3506 cooperating with the liquid outlet joint 3540 are provided at the bottom of the cleaning table 3500, a liquid outlet cavity 3550 is formed between the liquid outlet joint 3540 and the third trough body 3506, a fourth through hole 3541, a fifth through hole 3542 and a second liquid outlet pipe 3543 are provided on the liquid outlet joint 3540, the fourth through hole 3541 is located below the cleaning hole 3501 and is coaxial with the cleaning hole 3501, the second liquid outlet pipe 3543 extends to the bottom of the cleaning table 3500 and is connected with the fourth through hole 3541, the fifth through hole 3542 is respectively connected with the fourth through hole 3541 and the liquid outlet cavity 3550, and the fifth through hole 3542 is inclined downward in the direction of the liquid outlet cavity 3550. Among them, the second liquid outlet pipe 3543 can be arranged in the vertical direction and coaxial with the fourth through hole 3541, the fifth through hole 3542 can be a plurality of evenly distributed along the circumferential direction of the liquid outlet joint 3540, and the first liquid outlet pipe 3503 and the second liquid outlet pipe 3543 can be connected to the corresponding cleaning liquid collection device through pipelines respectively. Thus, the cleaning liquid for external cleaning and internal cleaning of the sample needle 3100 or the reagent needle 3300 can be discharged through the fifth through hole 3542 and the second liquid outlet pipe 3543, and the fifth through hole 3542 is arranged obliquely to facilitate the cleaning liquid to flow out more smoothly into the liquid outlet cavity 3550 and be discharged from the first liquid outlet pipe 3503, thereby ensuring better discharge of the cleaning liquid, more convenient operation, and a more compact and stable structure.

[0074] Based on the above-mentioned embodiments of the present disclosure, in the absence of explicit negation or conflict, the technical features of one embodiment may be beneficially combined with one or more other embodiments.

[0075] The above are only some embodiments of the present application, which are only used to illustrate the technical solution of the present application, rather than to limit it. It should be understood that, for those skilled in the art, without departing from the creative concept of the present application, it is possible to improve or replace it according to the above description, and all these improvements and replacements should belong to the protection scope of the claims attached to the present application. In this case, all details can be replaced by equivalent elements, and the materials, shapes and sizes can also be arbitrary.

Claims

1. A liquid taking and adding device, characterized in that: include: A sample needle, wherein the sample needle is arranged in a vertical direction; A first driving component, wherein the first driving component drives the sample needle to move in the X direction, the Y direction and the Z direction respectively; A reagent needle, the reagent needle is arranged in a vertical direction, and the sample needle and the reagent needle are respectively connected to a suction pump through pipelines; a second driving assembly, wherein the second driving assembly drives the sample needle to move in the X direction, the Y direction and the Z direction respectively; A cleaning table, wherein the cleaning table is located below the sample needle and the reagent needle, and is provided with a calibration element, a cleaning hole, and a liquid inlet hole and a liquid outlet hole respectively connected to the cleaning hole, wherein the liquid inlet hole and the liquid outlet hole are used for the inlet and outlet of the cleaning liquid, and the calibration element is used for calibrating the sample needle or the reagent needle, and the cleaning hole is arranged in a vertical direction, the liquid inlet hole is located at the upper end of the cleaning hole, and the liquid outlet hole is located at the lower end of the cleaning hole.

2. The liquid taking and adding device according to claim 1, characterized in that: The first driving assembly and the second driving assembly are mounted on a fixing plate and are located below the fixing plate.

3. The liquid taking and adding device according to claim 2, characterized in that: The fixing plate is provided with control components respectively matched with the first driving component and the second driving component, and the control components are located above the fixing plate.

4. The liquid taking and adding device according to claim 2, characterized in that: The first driving assembly comprises: A first driving member, wherein the first driving member is mounted on the first connecting plate, the upper end of the sample needle is mounted on the connecting seat, the first driving member is connected to the connecting seat, and the first driving member drives the connecting seat and the sample needle to move together along the Z direction; a second driving member, the second driving member is mounted on a second connecting plate, the second driving member is connected to the first connecting plate, and the second driving member drives the first connecting plate and the first driving member to move together along the X direction; A third driving member is mounted on the fixed plate, the third driving member is connected to the second connecting plate, and the third driving member drives the second connecting plate and the second driving member to move along the Y direction together.

5. The liquid taking and adding device according to claim 4, characterized in that: The third driving member is a motor with an encoder, and the output shaft of the third driving member is connected to the second connecting plate through a transmission mechanism. The fixed plate is provided with a guide mechanism that cooperates with the second connecting plate. The guide mechanism is a linear slide rail arranged along the Y direction, and the transmission mechanism is a synchronous belt mechanism.

6. The liquid taking and adding device according to claim 4, characterized in that: A connector is arranged on the top of the sample needle, a protective shell matching with the connector is arranged on the connection seat, and a first through hole for a pipeline to pass through is arranged on the protective shell.

7. The liquid taking and adding device according to claim 1, characterized in that: The calibration element is made of conductive metal material, a circular calibration hole is arranged on the top of the calibration element, a first slot body for accommodating the calibration element is arranged on the cleaning table, and the top of the calibration element is higher than the top of the first slot body.

8. The liquid taking and adding device according to claim 1, characterized in that: An upper cover is provided on the top of the cleaning station, a liquid inlet connector is provided on the upper cover, a second through hole for the sample needle or the reagent needle to pass through is provided on the liquid inlet connector, the second through hole is located above the cleaning hole and is connected to the cleaning hole, an extension portion extending to one side of the top of the cleaning station is provided on the upper cover, and the calibration element is arranged on the extension portion.

9. The liquid taking and adding device according to claim 8, characterized in that: A second trough body matched with the liquid inlet joint is provided on the top of the cleaning table, the bottom of the liquid inlet joint is pressed against the bottom surface of the second trough body, a liquid inlet cavity is formed between the liquid inlet joint and the second trough body, the liquid inlet hole is communicated with the liquid inlet cavity, a third through hole is provided on the liquid inlet joint, the third through hole is communicated with the liquid inlet cavity and the second through hole respectively, the third through hole is inclined downward in the direction of the second through hole, the third through holes are multiple and evenly distributed along the circumferential direction of the liquid inlet joint, and a sealing ring is provided between the liquid inlet joint and the second trough body.

10. The liquid taking and adding device according to claim 9, characterized in that: The liquid inlet hole is connected to a liquid inlet pipe, and the liquid inlet pipe and the suction pump are respectively connected to corresponding cleaning liquid supply devices through pipelines. A liquid outlet joint and a third trough body matched with the liquid outlet joint are provided at the bottom of the cleaning table. A liquid outlet cavity is formed between the liquid outlet joint and the third trough body. A fourth through hole, a fifth through hole and a second liquid outlet pipe are provided on the liquid outlet joint. The fourth through hole is located below the cleaning hole and is coaxial with the cleaning hole. The second liquid outlet pipe extends to the bottom of the cleaning table and is connected with the fourth through hole. The fifth through hole is respectively connected with the fourth through hole and the liquid outlet cavity. The fifth through hole is inclined downward in the direction of the liquid outlet cavity. The fifth through hole is a plurality of evenly distributed fifth through holes along the circumferential direction of the liquid outlet joint. The liquid outlet is connected to the first liquid outlet pipe.