Filtering device for producing egg yolk antibody semi-finished product

Abstract

The utility model discloses a filtering device for producing egg yolk antibody semi-finished products. The filtering device comprises a tank body, a centrifugal cylinder is arranged in the tank body, a connecting box is connected below the tank body, a sealing box is connected below the connecting box, and a negative pressure cavity is formed in the sealing box; the centrifugal cylinder is connected with a motor; the motor is provided with a belt wheel I; a filter screen is arranged in the connecting box; a negative pressure mechanism is arranged on one side of the negative pressure cavity and comprises a second belt wheel, a belt is arranged between the second belt wheel and the first belt wheel, the first belt wheel drives the second belt wheel to conduct transmission through the belt, the second belt wheel drives the negative pressure mechanism to extract gas in the sealing box, and a negative pressure environment is formed in the sealing box; the vaccine production filtering efficiency is improved.

Description

Technical Field

[0001] The utility model belongs to the field of vaccine production equipment, in particular to a filtering device for producing semi-finished yolk antibody products. Background Art

[0002] By immunizing laying hens, the corresponding antibodies can be extracted from the egg yolks produced by them, and can be used for the prevention and treatment of corresponding diseases. The collected egg yolks are separated into egg yolk clear liquid by centrifugation or other methods, and the egg yolk clear liquid is filtered, clarified, and other treatment methods to remove impurities.

[0003] In the prior art, a yolk antibody filtering and clarifying device is used to repeatedly or continuously inject the yolk antibody stock solution into the filter bag system fixed on the temporary storage barrel through the pipe connected to the reaction tank, and the yolk antibody stock solution is collected into the temporary storage barrel through the filter bag, and transferred to the yolk antibody raw material tank through the discharge port connecting pipe at the bottom of the temporary storage barrel, and the transfer process is powered by a mechanical pump. In the prior art, the yolk is clarified and filtered by the natural gravity, the filtration time is long, and repeated filtration is required, and the filtration efficiency is low. Utility Model Content

[0004] In view of the shortcomings of the prior art, the purpose of the present invention is to provide a filtering device for producing semi-finished yolk antibody products, which at least solves one of the problems of the background technology and improves the filtering efficiency of vaccines.

[0005] The utility model provides the following technical solutions:

[0006] A filtering device for producing semi-finished yolk antibody products, comprising a tank body, a centrifugal drum arranged in the tank body, a connecting box connected below the tank body, a sealing box connected below the connecting box, and a negative pressure chamber in the sealing box;

[0007] The centrifugal cylinder is connected to a motor, and the motor is provided with a pulley 1;

[0008] A filter is provided in the connection box;

[0009] A negative pressure mechanism is provided on one side of the negative pressure chamber, and the negative pressure mechanism includes a second pulley, a belt is provided between the second pulley and the first pulley, the first pulley drives the second pulley through the belt, and the second pulley drives the negative pressure mechanism to extract the gas in the sealed box, so that a negative pressure environment is formed in the sealed box;

[0010] The bottom of the sealing box is connected with a storage box, and the storage box is provided with a discharge pipe.

[0011] Preferably, the output shaft of the motor passes through the tank body and is connected to the centrifuge cylinder. The centrifuge cylinder is provided with a movable door, which is opened on the side wall of the centrifuge cylinder and is locked and connected to the side wall of the centrifuge cylinder.

[0012] Preferably, two slide grooves are symmetrically opened on the inner wall of the connection box near the top, and the slide grooves are of "T"-shaped structure. The side wall of the connection box is provided with an opening, and clamping plates are provided on both sides of the filter screen. The clamping plates are of "T"-shaped structure and can be slidably connected with the slide grooves. A sealing plate is connected to one end of the two clamping plates, and the sealing plate is connected to the filter screen. The sealing plate can cover and seal the side wall opening of the connection box.

[0013] Preferably, the negative pressure mechanism also includes a shell, the shell is connected to the outer wall of the sealing box, the second pulley is rotatably connected to the outer wall of the shell, a driving gear is provided on the second pulley, the driving gear is meshingly connected to a driven gear, a transmission shaft connected to the driven gear passes through the shell and is rotatably connected to the shell, the other end of the transmission shaft of the driven gear is connected to a turntable, the turntable is arranged inside the shell, the other side of the turntable is eccentrically rotatably connected to a rotating rod, the other end of the rotating rod is rotatably connected to a moving rod, the other end of the moving rod is provided with a box body, the moving rod passes through the box body wall, and is slidably connected to the box body wall.

[0014] Preferably, an air guide tube is provided on one side of the box body, the other end of which is connected to the negative pressure chamber, and an air outlet pipe is provided on the other side of the box body, which is connected to the outside.

[0015] Preferably, a first partition plate and a second partition plate are provided in the box body, a cavity is formed between the first partition plate and the second partition plate, a piston is provided between the first partition plate and the second partition plate, and one side of the piston is connected to the moving rod.

[0016] Preferably, the first partition is provided with a first air guide port and a second air guide port near both ends, the second partition is provided with a first exhaust port and a second exhaust port near both ends, an air guide cavity is formed between the first partition and the box body wall, and an exhaust cavity is formed between the second partition and the box body wall; the piston plate separates the cavities, one side is the upper cavity, and the other side is the lower cavity.

[0017] Preferably, the first air inlet and the second air inlet are both located on one side of the cavity and are provided with an air guide door, and the air guide door is rotatably connected to the first partition through a set hinge; the first exhaust port and the second exhaust port are both located on one side of the exhaust cavity and are provided with an exhaust valve, and the exhaust valve is rotatably connected to the second partition through a set hinge.

[0018] Preferably, a transparent display window is provided on the side wall of the storage box, the display window is made of glass, scale lines are provided on the display window, and a valve is provided on the discharge pipe.

[0019] Preferably, when the filter needs to be replaced, the sealing plate is pulled outward, and the sealing plate drives the block on the filter to slide out of the slide groove. The new filter is fixed on the block and the sealing plate and inserted into the slide groove to complete the replacement, thereby increasing the convenience of operation.

[0020] Compared with the prior art, the utility model has the following beneficial effects:

[0021] The utility model discloses a filtering device for producing semi-finished products of egg yolk antibodies. When egg yolk liquid containing antibodies is centrifugally crushed, a motor drives a negative pressure mechanism to form a negative pressure environment in a negative pressure chamber. When the egg yolk liquid falls onto a filter screen, the filtering speed of the filter screen is slow, and large particles in the egg yolk cannot pass through the filter screen and are deposited on the filter screen. The filter screen forms a liquid seal, and an air pressure difference is formed in the negative pressure chamber and above the filtrate. The pressure above the filter screen is strong, which helps the clear liquid containing antibodies in the filtrate to quickly pass through the filter screen, thereby improving the filtering efficiency and saving the filtering time. After filtering, the clear liquid containing antibodies is stored in a storage box, and the capacity in the storage box can be observed through a display window. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] In order to more clearly illustrate the technical solution of the implementation mode of the utility model, the following is a brief introduction to the drawings required for use in the implementation mode. It should be understood that the following drawings only show certain embodiments of the utility model and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0023] Figure 1 It is a schematic diagram of the overall structure of the utility model.

[0024] Figure 2 It is a schematic diagram of the filter structure of the utility model.

[0025] Figure 3 It is a schematic diagram of the negative pressure mechanism of the utility model.

[0026] Figure 4 It is a schematic diagram of the internal structure of the box body of the utility model. DETAILED DESCRIPTION

[0027] In order to make the purpose, technical solution and advantages of the implementation mode of the utility model clearer, the technical solution in the implementation mode of the utility model will be clearly and completely described below in conjunction with the drawings in the implementation mode of the utility model. Obviously, the described implementation mode is a part of the implementation mode of the utility model, not all the implementation modes. Based on the implementation mode in the utility model, all other implementation modes obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0028] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without creative work are within the scope of protection of the present invention. Example

[0029] refer to Figure 1-2 A filtering device for producing semi-finished yolk antibody products, comprising a tank body 1, a centrifugal drum 2 is arranged in the tank body 1, a connecting box 5 is connected below the tank body 1, a sealing box 6 is connected below the connecting box 5, and a negative pressure chamber 7 is arranged in the sealing box 6; the centrifugal drum 2 is connected to a motor 3, and the motor 3 is provided with a pulley 4; a filter screen 51 is arranged in the connecting box 5;

[0030] A negative pressure mechanism 13 is provided on one side of the negative pressure chamber 7. The negative pressure mechanism 13 includes a second pulley 12. A belt 11 is provided between the second pulley 12 and the first pulley 4. The first pulley 4 drives the second pulley 12 through the belt 11. The second pulley 12 drives the negative pressure mechanism 13 to extract the gas in the sealing box 6, so that a negative pressure environment is formed in the sealing box 6. A storage box 8 is connected to the bottom of the sealing box 6, and the storage box 8 is provided with a discharge pipe 10.

[0031] The output shaft of the motor 3 passes through the tank body 1 and is connected to the centrifugal cylinder 2. The centrifugal cylinder 2 is provided with a movable door, which is opened on the side wall of the centrifugal cylinder 2 and is locked and connected with the side wall of the centrifugal cylinder 2. Two chute 53 are symmetrically opened near the top of the inner wall of the connecting box 5. The chute 53 is a "T"-shaped structure. The side wall of the connecting box 5 is provided with an opening. Both sides of the filter 51 are provided with a card plate 52. The card plate 52 is a "T"-shaped structure and can be slidably connected with the chute 53. One end of the two card plates 52 is connected to a sealing plate 54, which is connected to the filter 51. The sealing plate 54 can cover and seal the side wall opening of the connecting box 5. The side wall of the storage box 8 is provided with a transparent display window 9, which is made of glass and has scale lines on it. The discharge pipe 10 is provided with a valve.

[0032] When the filter 51 needs to be replaced, the sealing plate 54 is pulled outward, and the sealing plate 54 drives the block on the filter 51 to slide out of the slide groove 53. The new filter 51 is fixed on the block and the sealing plate 54 and inserted into the slide groove 53 to complete the replacement, thereby increasing the convenience of operation. Example

[0033] Based on Example 1, refer to Figure 3-4The negative pressure mechanism 13 also includes a shell 131, which is connected to the outer wall of the sealing box 6, and the pulley 12 is rotatably connected to the outer wall of the shell 131. The pulley 12 is provided with a driving gear 132, and the driving gear 132 is meshed with a driven gear 133. The transmission shaft connected to the driven gear 133 passes through the shell 131 and is rotatably connected to the shell 131. The other end of the transmission shaft of the driven gear 133 is connected to a turntable 134, and the turntable 134 is arranged inside the shell 131. The other side of the turntable 134 is eccentrically rotatably connected to a rotating rod 135, and the other end of the rotating rod 135 is rotatably connected to a moving rod 136. The other end of the moving rod 136 is provided with a box body 137, and the moving rod 136 passes through the wall of the box body 137 and is slidably connected to the wall of the box body 137.

[0034] An air guide tube 140 is provided on one side of the box body 137, and the other end of the air guide tube 140 is connected to the negative pressure chamber 7. An air outlet pipe 141 is provided on the other side of the box body 137, and the air outlet pipe 141 is connected to the outside. A first partition plate 138 and a second partition plate 139 are provided in the box body 137, and a cavity is formed between the first partition plate 138 and the second partition plate 139. A piston 144 is provided between the first partition plate 138 and the second partition plate 139, and one side of the piston 144 is connected to the moving rod 136.

[0035] The first baffle 138 is provided with a first air guide port 147 and a second air guide port 148 near both ends, and the second baffle 139 is provided with a first exhaust port 149 and a second exhaust port 150 near both ends. An air guide cavity 142 is formed between the first baffle 138 and the wall of the box body 137, and an exhaust cavity 143 is formed between the second baffle 139 and the wall of the box body 137; the piston 144 separates the cavity, one side is the upper cavity 145, and the other side is the lower cavity 146. The first air guide port 147 and the second air guide port 148 are both provided with an air guide door on one side of the cavity, and the air guide door is rotatably connected to the first baffle 138 through a hinge; the first exhaust port 149 and the second exhaust port 150 are both provided with an exhaust valve on one side of the exhaust cavity 143, and the exhaust valve is rotatably connected to the second baffle 139 through a hinge.

[0036] Specifically, in the present technical solution, when filtering, the egg yolk containing the antibody is added to the centrifugal cylinder 2, the motor 3 is started to drive the centrifugal cylinder 2 to rotate, and the clear liquid containing the antibody is subjected to the centrifugal effect for the first filtration. When the motor 3 rotates, the pulley 12 is driven to rotate through the pulley 1 4. When the pulley 12 rotates, it drives the driving gear 132 and the driven gear 133 to rotate. The driven gear 133 drives the rotating rod 135 to rotate, and the moving rod 136 moves up and down following the rotating rod 135. The piston 144 moves up and down in the cavity through the action of the moving rod 136. When the piston 144 moves upward, the air guide valve of the second air guide port 148 is opened by the negative pressure, and the exhaust valve of the second exhaust port 150 is closed by the negative pressure. The gas in the negative pressure chamber 7 enters the lower cavity 146 through the air guide pipe 140, the air guide cavity 142, and the second air guide port 148; at this time, the air guide valve of the first air guide port 147 is closed by the pressure, and the exhaust valve of the first exhaust port 149 is closed. The valve is opened by pressure, and the gas in the upper cavity 145 enters the exhaust cavity 143 and the exhaust pipe 141 through the first exhaust valve; when the piston 144 moves downward, the principle is the same as above, the gas in the negative pressure cavity 7 enters the upper cavity 145, and the gas in the lower cavity 146 is discharged outward through the second exhaust port 150; through the above process, when the egg yolk liquid containing antibodies is centrifugally crushed, the motor 3 drives the negative pressure mechanism 13 to form a negative pressure environment in the negative pressure cavity 7, when the egg yolk liquid falls onto the filter 51, the filtering speed of the filter 51 is slow, and the large particles in the egg yolk cannot pass through the filter 51, and are deposited on the filter 51, and the filter 51 will form a liquid seal, and a pressure difference is formed between the negative pressure cavity 7 and the top of the filtrate. The pressure above the filter 51 is strong, which helps the clear liquid containing antibodies in the filtrate to quickly pass through the filter 51, improve the filtering efficiency, and save filtering time. After filtering, the clear liquid containing antibodies is stored in the storage box 8, and the capacity in the storage box 8 is observed through the display window 9.

[0037] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and changes. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A filtering device for producing semi-finished egg yolk antibody, characterized in that: It comprises a tank body (1), a centrifugal cylinder (2) is arranged in the tank body (1), a connection box (5) is connected below the tank body (1), a sealing box (6) is connected below the connection box (5), and a negative pressure chamber (7) is arranged inside the sealing box (6); The centrifuge cylinder (2) is connected to a motor (3), and the motor (3) is provided with a pulley (4); A filter screen (51) is provided in the connection box (5); A negative pressure mechanism (13) is provided on one side of the negative pressure chamber (7), the negative pressure mechanism (13) comprising a second pulley (12), a belt (11) being provided between the second pulley (12) and the first pulley (4), the first pulley (4) driving the second pulley (12) via the belt (11), the second pulley (12) driving the negative pressure mechanism (13) to extract the gas in the sealing box (6), thereby forming a negative pressure environment in the sealing box (6); The bottom of the sealing box (6) is connected to a storage box (8), and the storage box (8) is provided with a discharge pipe (10).

2. A filtering device for producing a semi-finished product of egg yolk antibody according to claim 1, characterized in that: The output shaft of the motor (3) passes through the tank body (1) and is connected to the centrifuge cylinder (2). The centrifuge cylinder (2) is provided with a movable door, which is opened on the side wall of the centrifuge cylinder (2). The movable door is locked and connected to the side wall of the centrifuge cylinder (2).

3. A filtering device for producing semi-finished egg yolk antibody according to claim 1, characterized in that: Two slide grooves (53) are symmetrically provided at positions near the top of the inner side wall of the connection box (5), the slide grooves (53) being of a "T"-shaped structure. The side wall of the connection box (5) is provided with an opening. A clamping plate (52) is provided on both sides of the filter screen (51), the clamping plate (52) being of a "T"-shaped structure and being slidably connected to the slide groove (53). A sealing plate (54) is connected to one end of the two clamping plates (52), the sealing plate (54) being connected to the filter screen (51), and the sealing plate (54) being capable of covering and sealing the side wall opening of the connection box (5).

4. A filtering device for producing a semi-finished product of egg yolk antibody according to claim 1, characterized in that: The negative pressure mechanism (13) further comprises a shell (131), wherein the shell (131) is connected to the outer wall of the sealing box (6), the second pulley (12) is rotatably connected to the outer wall of the shell (131), the second pulley (12) is provided with a driving gear (132), the driving gear (132) is meshingly connected to a driven gear (133), a transmission shaft connected to the driven gear (133) passes through the shell (131) and is rotatably connected to the shell (131), the other end of the transmission shaft of the driven gear (133) is connected to a rotating disk (134), the rotating disk (134) is arranged inside the shell (131), the other side of the rotating disk (134) is eccentrically rotatably connected to a rotating rod (135), the other end of the rotating rod (135) is rotatably connected to a moving rod (136), the other end of the moving rod (136) is provided with a box body (137), the moving rod (136) passes through the wall of the box body (137) and is slidably connected to the wall of the box body (137).

5. A filtering device for producing semi-finished egg yolk antibody according to claim 4, characterized in that: An air guide tube (140) is provided on one side of the box body (137), the other end of the air guide tube (140) is in communication with the negative pressure chamber (7), and an air outlet tube (141) is provided on the other side of the box body (137), the air outlet tube (141) is in communication with the outside.

6. A filtering device for producing a semi-finished product of egg yolk antibody according to claim 5, characterized in that: A first partition plate (138) and a second partition plate (139) are provided in the box body (137), a cavity is formed between the first partition plate (138) and the second partition plate (139), a piston (144) is provided between the first partition plate (138) and the second partition plate (139), and one side of the piston (144) is connected to the moving rod (136).

7. A filtering device for producing semi-finished egg yolk antibody according to claim 6, characterized in that: The first baffle (138) is provided with a first air guide port (147) and a second air guide port (148) near both ends, and the second baffle (139) is provided with a first exhaust port (149) and a second exhaust port (150) near both ends; an air guide cavity (142) is formed between the first baffle (138) and the wall of the box body (137), and an exhaust cavity (143) is formed between the second baffle (139) and the wall of the box body (137); a piston (144) plate separates the cavities, one side of which is an upper cavity (145) and the other side is a lower cavity (146).

8. A filtering device for producing semi-finished egg yolk antibody according to claim 7, characterized in that: The first air guide port (147) and the second air guide port (148) are both provided with air guide doors on one side of the cavity, and the air guide doors are rotatably connected to the first partition plate (138) via a hinge; the first exhaust port (149) and the second exhaust port (150) are both provided with exhaust doors on one side of the exhaust cavity (143), and the exhaust doors are rotatably connected to the second partition plate (139) via a hinge.

9. A filtering device for producing semi-finished egg yolk antibody according to claim 1, characterized in that: A transparent display window (9) is provided on the side wall of the storage box (8); the display window (9) is made of glass and has scale lines on it; and a valve is provided on the discharge pipe (10).

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