Sample feeding device of dissolution instrument

By designing a dissolution instrument sample delivery device including support, pillar, adjustment bolt, sample box and pull rod, the problem of the difference in drug time in traditional manual drug delivery is solved, and the synchronous placement of multiple samples and consistency of dissolution results is achieved.

CN222838056UActive Publication Date: 2025-05-06TIANJIN TIANFA BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202420773558.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-15
Publication Date
2025-05-06
Estimated Expiration
2034-04-15

AI Technical Summary

Technical Problem

The traditional manual dosing method has a difference in dosage time in drug dissolution test, which leads to large differences in dissolution results of drug samples in different dissolution cups, making it difficult to ensure the consistency of the test results.

Method used

A dissolution instrument sample delivery device is designed, including support, pillar, adjustment bolt, sample box and pull rod. By adjusting the base height and sample box spacing, the synchronous placement of multiple sample boxes is achieved.

Benefits of technology

This device can ensure the simultaneous delivery of multiple samples, reduce the dosing time difference and improve the consistency of the dissolution results of drug samples in different dissolution cups.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of medicine dissolving-out equipment, in particular to a dissolving-out instrument sample feeding device which comprises a support, two supporting columns are fixed at the top end of the support, a base and two adjusting bolts are arranged above the support, a through groove is formed in the base, a plurality of sample boxes with missing bottom ends are arranged in the through groove, baffles are arranged in the plurality of sample boxes, and the two adjusting bolts are arranged in the through groove. The top ends of the multiple baffles are constructed to be inclined planes, two locking bolts are arranged above each baffle, two screw holes matched with the locking bolts are formed in each sample box, a pull rod is arranged on one side of the base, connecting blocks are fixed to the side walls, close to the pull rod, of the multiple baffles, the pull rod penetrates through the multiple connecting blocks, two guide rods are fixed to the pull rod, and the guide rods are connected with the sample boxes. The two guide rods are sleeved with springs, and check blocks are fixed to the ends, away from the pull rod, of the two guide rods. The pull rod is pulled, the multiple connecting blocks drive the multiple baffles to move, the samples in the multiple sample boxes fall down synchronously, and the multiple samples can be put at the same time conveniently.
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Description

Technical Field

[0001] The utility model relates to the technical field of drug dissolution equipment, in particular to a dissolution instrument sample feeding device. Background Art

[0002] Drug solubility is an important indicator of drug quality control. The absorption rate of drugs in the body is often determined by the speed of dissolution. Before being absorbed, drugs in solid preparations must undergo a process of disintegration and dissolution and then be converted into solutions. If the drug is not easy to release from the preparation or the dissolution rate of the drug is extremely slow, there may be problems with the absorption rate or degree of the drug in the preparation. Therefore, measuring the dissolution rate of drugs is a key step for pharmaceutical companies when developing drugs. When performing drug dissolution tests, drug samples need to be put into dissolution cups. The traditional manual dosing method requires the experimenter to manually put the tablets into the dissolution cups one by one at a certain time interval and time them separately. This drug sample dosing method has a dosing time difference. In the case of batch testing of samples, it is difficult to ensure that the dissolution time of drug samples in each dissolution cup is consistent, resulting in large differences in the dissolution results between drug samples in different dissolution cups. Therefore, a dissolution instrument sampling device is proposed to facilitate the simultaneous placement of multiple samples. Utility Model Content

[0003] In view of the problems in the prior art, the utility model provides a sample feeding device for a dissolution instrument.

[0004] The technical solution adopted by the utility model to solve the technical problem is a dissolution instrument sample feeding device, including a support, two pillars are fixed on the top of the support, a base and two adjusting bolts are arranged above the support, the tops of the two pillars pass through the base, screw holes adapted to the adjusting bolts are opened on both sides of the base, and multiple slots adapted to the adjusting bolts are opened on the side walls opposite to the two pillars, a through groove is arranged on the base, and multiple sample boxes with missing bottom ends are arranged in the through groove, and baffles are arranged in multiple sample boxes, and the tops of multiple baffles are constructed as inclined surfaces, each Two locking bolts are provided above each of the baffles, and two screw holes matching the locking bolts are provided on each of the sample boxes. A pull rod is provided on one side of the base, and connecting blocks are fixed to the side walls of multiple baffles close to the pull rod, and sliding grooves for the baffles to slide are provided on the side walls of multiple sample boxes close to the pull rod. The pull rod passes through multiple connecting blocks, and a sliding groove for the connecting blocks to slide is provided on the base. Two guide rods are fixed on the pull rod, and the ends of the two guide rods away from the pull rod pass through the base. Springs are sleeved on the two guide rods, and blocks are fixed to the ends of the two guide rods away from the pull rod.

[0005] By adopting the above technical solution, the base is slid, and the ends of the two adjusting bolts are screwed into the slots on the side walls of the two pillars. The height of the base can be adjusted as needed, and the locking bolt is loosened. After the sample box is slid, the locking bolt is tightened. The distance between two adjacent sample boxes can be adjusted according to the distance between two adjacent dissolution cups. Multiple sample boxes can store multiple samples to be injected at the same time. The baffle can block the samples in the sample box to prevent the samples from falling accidentally. When the samples need to be injected, the pull rod is held and pulled. The pull rod drives the multiple connecting blocks to move. The multiple connecting blocks drive the multiple baffles to move. The samples in the multiple sample boxes fall synchronously, which is convenient for the simultaneous injection of multiple samples. After the pull rod is released, the two springs push the two blocks to move during the resetting process, which is conducive to the resetting of the baffle and the next sampling use.

[0006] Specifically, a top plate is provided above the base, and the top plate is connected to two pillars.

[0007] By adopting the above technical solution and setting of the top plate, the stability of the two pillars can be improved.

[0008] Specifically, a handle is fixed to the top of the top plate.

[0009] By adopting the above technical solution, the whole device can be conveniently carried by holding the handle.

[0010] Specifically, a groove is provided on one side of the support, and a storage box is provided in the groove.

[0011] By adopting the above technical solution, the storage box can be pulled out, making it convenient to store and organize items.

[0012] Specifically, an anti-skid pad is fixed to the bottom end of the support.

[0013] By adopting the above technical solution, the support is placed on the desktop, and the anti-slip pad can improve the stability of the support.

[0014] Beneficial effects of the utility model:

[0015] (1) The utility model discloses a dissolution instrument sample feeding device, wherein the base is slidable, and the ends of two adjusting bolts are screwed into the slots of the side walls of the two pillars, so that the height of the base can be adjusted as needed. The locking bolts are loosened, and the locking bolts are tightened after the sample box is slid, so that the distance between two adjacent sample boxes can be adjusted according to the distance between two adjacent dissolution cups.

[0016] (2) The utility model discloses a dissolution instrument sampling device, wherein multiple sample boxes can store multiple samples to be sampled at the same time, and a baffle can block the samples in the sample box to prevent the samples from accidentally falling. When the samples need to be sampled, the pull rod is held and pulled, and the pull rod drives the multiple connecting blocks to move, and the multiple connecting blocks drive the multiple baffles to move, and the samples in the multiple sample boxes fall synchronously, which is convenient for simultaneously dropping multiple samples. After the pull rod is released, the two springs push the two baffles to move during the resetting process, which is beneficial for the resetting of the baffle and the next sampling. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The utility model is further described below in conjunction with the accompanying drawings and embodiments.

[0018] Figure 1 It is a schematic diagram of the structure of the utility model;

[0019] Figure 2 For the utility model Figure 1 A magnified view of the structure at center A;

[0020] Figure 3 For the utility model Figure 1 A magnified view of the structure at B in the middle.

[0021] In the figure: 1, support; 101, storage box; 102, anti-slip pad; 2, pillar; 3, connecting block; 4, pull rod; 5, top plate; 6, base; 7, handle; 8, sample box; 9, baffle; 10, locking bolt; 11, adjusting bolt; 12, guide rod; 13, spring; 14, stop block. DETAILED DESCRIPTION

[0022] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0023] In order to facilitate the simultaneous delivery of multiple samples, as an embodiment of the present utility model, Figure 1 , Figure 2 , Figure 3As shown, a dissolution instrument sampling device described in the utility model includes a support 1, two pillars 2 are welded and fixed on the top of the support 1, a base 6 and two adjusting bolts 11 are arranged above the support 1, the tops of the two pillars 2 pass through the base 6, both sides of the base 6 are provided with screw holes adapted to the adjusting bolts 11, and the side walls opposite to the two pillars 2 are provided with a plurality of slots adapted to the adjusting bolts 11, a through groove is provided on the base 6, and a plurality of sample boxes 8 with missing bottom ends are arranged in the through groove, and a plurality of the sample boxes 8 are provided with baffles 9, and the tops of the plurality of baffles 9 are constructed as inclined surfaces, and two baffles 9 are arranged above each of the baffles 9. A locking bolt 10 is provided on each of the sample boxes 8, and two screw holes matching the locking bolt 10 are provided on one side of the base 6. A pull rod 4 is provided on one side of the base 6. A plurality of baffles 9 are welded and fixed with connecting blocks 3 on the side walls close to the pull rod 4. A plurality of sample boxes 8 are provided with sliding grooves for the baffles 9 to slide on the side walls close to the pull rod 4. The pull rod 4 passes through a plurality of connecting blocks 3. A sliding groove for the connecting blocks 3 to slide is provided on the base 6. Two guide rods 12 are welded and fixed on the pull rod 4. The ends of the two guide rods 12 away from the pull rod 4 pass through the base 6. Springs 13 are sleeved on the two guide rods 12. Blocks 14 are welded and fixed on the ends of the two guide rods 12 away from the pull rod 4.

[0024] When in use, slide the base 6 and screw the ends of the two adjusting bolts 11 into the slots on the side walls of the two pillars 2. The height of the base 6 can be adjusted as needed. Loosen the locking bolt 10, slide the sample box 8 and tighten the locking bolt 10. The distance between two adjacent sample boxes 8 can be adjusted according to the distance between two adjacent dissolution cups. Multiple sample boxes 8 can store multiple samples to be injected at the same time. The baffle 9 can block the samples in the sample box 8 to prevent the samples from falling accidentally. When it is necessary to inject the samples, hold the pull rod 4 and pull it. The pull rod 4 drives the multiple connecting blocks 3 to move. The multiple connecting blocks 3 drive the multiple baffles 9 to move. The samples in the multiple sample boxes 8 fall synchronously, which is convenient for injecting multiple samples at the same time. After loosening the pull rod 4, the two springs 13 push the two baffles 14 to move during the resetting process, which is conducive to the resetting of the baffle 9 and the next sampling use.

[0025] In order to improve the stability of the pillar 2, for example, Figure 1 As shown, a top plate 5 is provided above the base 6 , and the top plate 5 is welded to the two pillars 2 .

[0026] For easy carrying, for example, Figure 1 As shown, a handle 7 is welded and fixed to the top end of the top plate 5 .

[0027] In order to facilitate the storage of items, for example, Figure 1 As shown, a groove is provided on one side of the support 1, and a storage box 101 is provided in the groove.

[0028] In order to improve the stability of the support 1, for example, Figure 1 As shown, a non-slip pad 102 is fixed to the bottom end of the support 1 by adhesive.

[0029] When the utility model is used, the support 1 is placed beside the dissolution instrument, the base 6 is slid, and the ends of the two adjusting bolts 11 are screwed into the slots of the side walls of the two pillars 2, so that the height of the base 6 can be adjusted as needed;

[0030] Loosen the locking bolt 10, slide the sample box 8 and tighten the locking bolt 10, so that the distance between two adjacent sample boxes 8 can be adjusted according to the distance between two adjacent dissolution cups;

[0031] Multiple sample boxes 8 can store multiple samples to be dosed at the same time, and the baffle 9 can block the samples in the sample box 8 to prevent the samples from falling accidentally. When the samples need to be dosed, the pull rod 4 is held and pulled, and the pull rod 4 drives the multiple connecting blocks 3 to move, and the multiple connecting blocks 3 drive the multiple baffles 9 to move. The samples in the multiple sample boxes 8 fall synchronously, which is convenient for the simultaneous delivery of multiple samples. After releasing the pull rod 4, the two springs 13 push the two baffles 14 to move during the resetting process, which is beneficial to the resetting of the baffle 9 and the next sampling use.

[0032] The above shows and describes the basic principles, main features and advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions in the specification are only to illustrate the principles of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the protection required by the utility model. The scope of protection required by the utility model is defined by the attached claims and their equivalents.

Claims

1. A dissolution apparatus sampling device, characterized in that: The invention comprises a support (1), wherein two pillars (2) are fixed at the top of the support (1), a base (6) and two adjusting bolts (11) are arranged above the support (1), the tops of the two pillars (2) pass through the base (6), screw holes adapted to the adjusting bolts (11) are arranged on both sides of the base (6), a plurality of slots adapted to the adjusting bolts (11) are arranged on the side walls opposite to each other of the two pillars (2), a through slot is arranged on the base (6), a plurality of sample boxes (8) with missing bottom ends are arranged in the through slot, a plurality of sample boxes (8) are arranged in a baffle (9), the tops of the plurality of baffles (9) are constructed as inclined surfaces, two locking bolts (10) are arranged above each of the baffles (9), and each of the sample boxes (8) is provided with a through slot. The box (8) is provided with two screw holes adapted to the locking bolts (10), a pull rod (4) is provided on one side of the base (6), a plurality of baffles (9) are fixed with connecting blocks (3) on the side walls close to the pull rod (4), a plurality of sample boxes (8) are provided with sliding grooves for the baffles (9) to slide on the side walls close to the pull rod (4), the pull rod (4) passes through a plurality of connecting blocks (3), a sliding groove for the connecting blocks (3) to slide is provided on the base (6), two guide rods (12) are fixed on the pull rod (4), the ends of the two guide rods (12) away from the pull rod (4) pass through the base (6), springs (13) are sleeved on the two guide rods (12), and baffles (14) are fixed on the ends of the two guide rods (12) away from the pull rod (4).

2. A dissolution apparatus sampling device according to claim 1, characterized in that: A top plate (5) is provided above the base (6), and the top plate (5) is connected to two pillars (2).

3. A dissolution apparatus sampling device according to claim 2, characterized in that: A handle (7) is fixed to the top end of the top plate (5).

4. A dissolution apparatus sampling device according to claim 1, characterized in that: A groove is provided on one side of the support (1), and a storage box (101) is provided in the groove.

5. A dissolution apparatus sampling device according to claim 1, characterized in that: An anti-slip pad (102) is fixed to the bottom end of the support (1).