Tube pressing device, cryopreservation tube picking assembly and biological sample cryopreservation device

Abstract

A tube pressing device, a cryopreservation tube picking assembly and a biological sample cryopreservation device.The cryopreservation tube picking device comprises a main body and a tube taking piece arranged at the lower end of the main body, the tube taking piece is used for picking a picked cryopreservation tube from a cryopreservation box, the cryopreservation box is used for containing a plurality of cryopreservation tubes, the tube pressing device comprises a connecting piece, one end of the connecting piece is connected with the main body, and the other end of the connecting piece is connected with the cryopreservation tube picking assembly; the other end of the connector is located at the lower end of the body; and the tube pressing plate is connected with the other end of the connecting piece, a tube picking hole corresponding to the position of the tube taking piece is formed in the tube pressing plate, the tube picking hole is used for picking the picked cryopreservation tubes by the tube taking piece, and the tube pressing plate is used for pressing at least part of the cryopreservation tubes in the cryopreservation box when the picked cryopreservation tubes are picked by the tube taking piece. In the process of picking out the picked cryopreservation tubes, at least part of the cryopreservation tubes of the picked cryopreservation tube accessory can be pressed by the tube pressing plate, so that the cryopreservation tubes are prevented from being picked up.

Description

Technical Field

[0001] The present application relates to the technical field of biological sample cryopreservation, and in particular to a tube pressing device, a cryopreservation tube picking assembly, and a biological sample cryopreservation device. Background Art

[0002] With the rapid development of the biopharmaceutical industry, large-scale biobanks have emerged, and the storage volume of biological samples is increasing. Generally, biological samples such as tissues and cells in clinical or laboratory settings are placed in cryotubes, which are then placed in cryoboxes for storage. However, in practice, cryotubes need to be picked out of cryoboxes, and in the process of picking out a cryotube, other cryotubes are easily picked up as well. Utility Model Content

[0003] In view of the above problems, the present application is proposed to provide a tube pressing device, a cryotube picking assembly and a biological sample freezing device that overcome the above problems or at least partially solve the above problems.

[0004] The present application provides a tube pressing device for a freezing tube picking device, the freezing tube picking device comprises a main body and a tube picking piece arranged at the lower end of the main body, the tube picking piece is used to pick up the picked freezing tube from a freezing box, the freezing box is used to place multiple freezing tubes, the tube pressing device comprises: a connecting piece, one end of the connecting piece is connected to the main body, and the other end of the connecting piece is located at the lower end of the main body; a tube pressing plate, the tube pressing plate is connected to the other end of the connecting piece, the tube pressing plate is provided with a tube picking hole corresponding to the position of the tube picking piece, the tube picking hole is used for the tube picking piece to pick up the picked freezing tube, and the tube pressing plate is used to press at least part of the freezing tubes in the freezing box when the tube picking piece picks up the picked freezing tube.

[0005] Optionally, one end of the connecting member is slidably connected to the main body, and the other end of the connecting member is fixedly connected to the tube pressing plate.

[0006] Optionally, an anti-wear component is provided at a position where one end of the connecting member is slidably connected to the main body.

[0007] Optionally, the connecting member is connected to an elastic member, and the elastic member is used to make the tube pressing plate be located below the tube taking member when no external force is applied thereto.

[0008] Optionally, the elastic member includes a spring sleeved outside the connecting member.

[0009] Optionally, the tube lifting hole is located at the center of the tube pressing plate.

[0010] Optionally, a tube pressing protrusion is provided at the bottom of the tube pressing plate, and the tube pressing plate presses at least part of the cryogenic tubes in the cryogenic box through the tube pressing protrusion.

[0011] Optionally, there are multiple connecting members, including a first connecting member and a second connecting member that are arranged opposite to each other.

[0012] The present application also provides a freezing tube picking assembly, comprising: a freezing tube picking device, comprising a main body and a tube picking piece arranged at the lower end of the main body, the tube picking piece is used to pick up the picked freezing tube from a freezing box, and the freezing box is used to place multiple freezing tubes; any of the above-mentioned tube pressing devices, one end of the connecting piece of the tube pressing device is connected to the main body, and the other end of the connecting piece is located at the lower end of the main body, the tube picking hole of the tube pressing device is used for the tube picking piece to pick up the picked freezing tube, and the tube pressing plate is used to press at least part of the freezing tubes in the freezing box when the tube picking piece picks up the picked freezing tube.

[0013] The present application also provides a biological sample freezing device, comprising: a cavity, which defines a storage area for storing a freezing box and a tube picking area for picking up a frozen tube from the freezing box; the above-mentioned freezing tube picking assembly, which is arranged in the tube picking area.

[0014] The tube pressing device, cryotube picking assembly and biological sample freezing device provided in the present application can press at least part of the cryotubes attached to the picked cryotubes through the tube pressing plate during the process of picking out the picked cryotubes, thereby preventing these cryotubes from being picked up. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Other objects and advantages of the present application will be apparent from the following description of the present application with reference to the accompanying drawings, which will help to provide a comprehensive understanding of the present application.

[0016] Figure 1 is a front view of a tube pressing device and a cryotube picking device according to some embodiments of the present application;

[0017] Figure 2 is a stereoscopic diagram of a pipe pressing device and a main body according to some embodiments of the present application;

[0018] Figure 3 is a first perspective view of a pipe pressing device according to some embodiments of the present application;

[0019] Figure 4 This is a second viewing angle diagram of the pipe pressing device according to some embodiments of the present application.

[0020] In the figure, 10 is a tube picking device for cryotubes, 100 is a main body, 200 is a tube taking member, 20 is a tube pressing device, 300 is a connecting member, 310 is a first connecting member, 320 is a second connecting member, 400 is a tube pressing plate, 410 is a tube picking hole, 420 is a tube pressing protrusion, and 500 is an anti-wear member. DETAILED DESCRIPTION

[0021] In order to make the purpose, technical solution and advantages of the present application clearer, the technical solution of the present application will be clearly and completely described below in conjunction with the drawings of the embodiments of the present application. Obviously, the described embodiment is one embodiment of the present application, not all embodiments. Based on the described embodiments of the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0022] Unless otherwise defined, technical or scientific terms used in this application should have the common meanings understood by persons having ordinary skills in the field to which this application belongs.

[0023] The present embodiment provides a tube pressing device 20 for a freezing tube picking device 10, wherein the freezing tube picking device 10 comprises a main body 100 and a tube taking member 200 disposed at the lower end of the main body 100, wherein the tube taking member 200 is used to pick up a picked freezing tube from a freezing box, wherein the freezing box is used to place a plurality of freezing tubes, and wherein the tube pressing device 20 comprises: a connecting member 300, wherein one end of the connecting member 300 is connected to the main body 100, and the other end of the connecting member 300 is located at the lower end of the main body 100; and a tube pressing plate 400, wherein the tube pressing plate 400 is connected to the other end of the connecting member 300, and wherein the tube pressing plate 400 is provided with a tube picking hole 410 corresponding to the position of the tube taking member 200, wherein the tube picking hole 410 is used for the tube taking member 200 to pick up the picked freezing tube, and wherein the tube pressing plate 400 is used to press at least part of the freezing tubes in the freezing box when the tube taking member 200 picks up the picked freezing tube.

[0024] Cryotubes are special containers used in laboratories to store biological samples at low temperatures. These biological samples may include cells, tissues, DNA, RNA, etc. A cryotube is a storage device specifically used to store biological samples in a low-temperature environment. There are several small grooves inside the box for storing cryotubes. A cryotube can hold multiple cryotubes. When a user uses a cryotube, the user needs to pick out the cryotube. The cryotube that needs to be picked is called a picked cryotube (for the convenience of description only, and does not mean that the shape, structure, etc. of the picked cryotube are necessarily different from other cryotubes). A cryotube picking device 10 can be used to pick the picked cryotube.

[0025] The main body 100 of the cryotube picking device 10 can be a disc, a square or other structure, which is used to install the tube picking component 200. The tube picking component 200 can be a clamp, an adsorption device, a clamping device, etc., which is used to clamp, adsorb or hold the picked cryotube.

[0026] Since the cryotube is placed in a low-temperature environment, ice may form between the picked cryotube and other cryotubes, causing the picked cryotube to stick together with other surrounding cryotubes. When the picked cryotube is lifted up, other surrounding cryotubes will be lifted up, resulting in the risk of other cryotubes being lost, difficult to trace, and difficult to find. If other cryotubes are lifted up and fall, they may get stuck in some mechanisms, causing the risk of the biological sample freezing device being unable to complete automated operations.

[0027] The tube pressing device 20 provided in this embodiment can press at least part of the cryogenic tubes attached to the cryogenic tubes to be picked up through the tube pressing plate 400 during the process of picking out the cryogenic tubes to be picked up, thereby preventing these cryogenic tubes from being picked up.

[0028] The connecting member 300 may include a connecting rod. In other embodiments, the connecting member 300 may also be a connecting plate or other structures.

[0029] In some embodiments, one end of the connector 300 can be fixedly connected to the main body 100. The tube-taking fitting 200 can be higher than the tube-pressing plate 400, so that after the tube-pressing plate 400 presses other cryopreservation tubes, the tube-taking fitting 200 moves downward to pick up the cryopreservation tubes to be picked, that is, the tube-taking fitting 200 needs to move relative to the main body 100 in the up-down direction. The tube-taking fitting 200 can be flush with the tube-pressing plate 400, so that when the tube-pressing plate 400 presses other cryopreservation tubes, the tube-taking fitting 200 can pick up the cryopreservation tubes to be picked.

[0030] One end of the connecting member 300 is slidably connected to the main body 100, and the other end of the connecting member 300 is fixedly connected to the tube pressing plate 400. For example, the main body 100 is provided with a slide groove or a slide hole, and one end of the connecting member 300 is arranged in the slide groove or the slide hole. When the tube pressing plate 400 is located below the tube taking member 200 when no external force is applied, the tube taking member 200 does not need to move relative to the main body 100 in the up-down direction.

[0031] In some embodiments, a wear-resistant member 500 is provided at a position where one end of the connecting member 300 is slidably connected to the main body 100, thereby preventing the sliding member from being severely worn when sliding.

[0032] In some embodiments, the connector 300 is connected to an elastic member, and the elastic member is used to make the tube pressing plate 400 located below the tube taking member 200 when no external force is applied. The elastic member keeps the tube pressing plate 400 in position when no external force is applied, so as to better press other cryopreservation tubes.

[0033] The elastic member may include a spring sleeved outside the connecting member 300. Thus, the structure is stable and reliable. In other embodiments, a spring sheet, a rubber strip, etc. may be used.

[0034] In some embodiments, the tube picking hole 410 is located at the center of the tube pressing plate 400. Thus, other cryopreservation tubes around the picked cryopreservation tube can be prevented from being lifted up.

[0035] In some embodiments, a tube pressing protrusion 420 is provided at the bottom of the tube pressing plate 400, and the tube pressing plate 400 presses at least part of the cryotubes in the cryopreservation box through the tube pressing protrusion 420. Thus, the contact area between the tube pressing plate 400 and other cryotubes is reduced, thereby preventing other cryotubes from adhering to the tube pressing plate 400. There may be a plurality of tube pressing protrusions 420, for example, a plurality of protrusions 420 evenly arranged at circumferential intervals.

[0036] In some embodiments, the connector 300 may be multiple, and include a first connector 310 and a second connector 320 that are arranged opposite to each other. Thus, the tube pressing member can press other cryopreservation tubes.

[0037] The present embodiment also provides a cryotube picking assembly, comprising: a cryotube picking device 10, comprising a main body 100 and a tube picking member 200 arranged at the lower end of the main body 100, the tube picking member 200 is used to pick up the picked cryotube from a cryobox, and the cryobox is used to place multiple cryotubes; any of the above-mentioned tube pressing devices 20, one end of the connecting member 300 of the tube pressing device 20 is connected to the main body 100, and the other end of the connecting member 300 is located at the lower end of the main body 100, the tube picking hole 410 of the tube pressing device 20 is used for the tube picking member 200 to pick up the picked cryotube, and the tube pressing plate 400 is used to press at least part of the cryotubes in the cryobox when the tube picking member 200 picks up the picked cryotube.

[0038] This embodiment also provides a biological sample freezing device, comprising: a cavity, the cavity defining a storage area for storing a freezing box and a tube picking area for picking a selected freezing tube from the freezing box; the above-mentioned freezing tube picking assembly, the tube picking assembly being arranged in the tube picking area. The biological sample freezing device can be a refrigerator, a cold storage, a storage device including a liquid nitrogen tank, etc.

[0039] The tube pressing device 20, the cryotube picking assembly and the biological sample freezing device provided in this embodiment can press at least part of the cryotubes attached to the picked cryotubes through the tube pressing plate 400 during the process of picking out the picked cryotubes, thereby preventing these cryotubes from being picked up.

[0040] Regarding the embodiments of the present application, it should also be noted that, in the absence of conflict, the embodiments of the present application and the features therein can be combined with each other to obtain new embodiments.

[0041] The above are only specific implementation methods of the present application, but the protection scope of the present application is not limited thereto. The protection scope of the present application shall be based on the protection scope of the claims.

Claims

1. A tube pressing device for a cryotube picking device, characterized in that: The freezing tube picking device comprises a main body and a tube taking member arranged at the lower end of the main body, wherein the tube taking member is used to pick the selected freezing tube from a freezing box, wherein the freezing box is used to place a plurality of freezing tubes, and the tube pressing device comprises: A connecting member, one end of which is connected to the main body, and the other end of which is located at the lower end of the main body; A tube pressing plate is connected to the other end of the connecting piece, and the tube pressing plate is provided with a tube picking hole corresponding to the position of the tube taking piece, and the tube picking hole is used for the tube taking piece to pick up the picked frozen tube. The tube pressing plate is used to press at least part of the frozen tubes in the freezing box when the tube taking piece picks up the picked frozen tube.

2. The pipe pressing device according to claim 1, characterized in that: One end of the connecting piece is slidably connected to the main body, and the other end of the connecting piece is fixedly connected to the tube pressing plate.

3. The pipe pressing device according to claim 2, characterized in that: An anti-wear part is arranged at a position where one end of the connecting part is slidably connected to the main body.

4. The pipe pressing device according to claim 1, characterized in that: The connecting member is connected to an elastic member, and the elastic member is used to make the tube pressing plate be located below the tube taking member when no external force is applied thereto.

5. The pipe pressing device according to claim 4, characterized in that: The elastic member comprises a spring sleeved outside the connecting member.

6. The pipe pressing device according to claim 1, characterized in that: The tube lifting hole is located at the center of the tube pressing plate.

7. The pipe pressing device according to claim 1, characterized in that: A tube pressing protrusion is arranged at the bottom of the tube pressing plate, and the tube pressing plate presses at least part of the freezing tubes in the freezing box through the tube pressing protrusion.

8. The pipe pressing device according to claim 1, characterized in that: The connecting members are multiple and include a first connecting member and a second connecting member that are arranged opposite to each other.

9. A cryotube picking assembly, characterized in that: include: A cryotube picking device comprises a main body and a tube picking member arranged at the lower end of the main body, wherein the tube picking member is used to pick a cryotube from a cryobox, and the cryobox is used to place a plurality of cryotubes; According to any one of claims 1 to 8, one end of the connecting piece of the tube pressing device is connected to the main body, and the other end of the connecting piece is located at the lower end of the main body. The tube picking hole of the tube pressing device is used for the tube picking piece to pick up the picked frozen tube, and the tube pressing plate is used to press at least part of the frozen tubes in the freezing box when the tube picking piece picks up the picked frozen tube.

10. A biological sample freezing device, characterized in that: include: The cavity defines a storage area for storing the cryopreservation box and a tube picking area for picking the selected cryopreservation tube from the cryopreservation box. ； According to the cryotube picking assembly of claim 9, the picking assembly is arranged in the picking area.

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