Purification column fixing structure
By designing a purified column fixing structure including a shell, connecting groove, connecting bump, top block and through hole, the sliding and rotation of the first clamp and the second clamp block is solved, and the existing fixing bracket is single and large in size is achieved, and the stable fixation and rapid release of the purified column is achieved, which is suitable for laboratory environments.
Patent Information
- Application Number
- CN202420375468.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-02-28
- Publication Date
- 2025-05-13
- Estimated Expiration
- 2034-02-28
AI Technical Summary
The existing purified column fixing scaffolds have a single fixing method and a large size, which cannot be adjusted and should not be used in laboratory environments.
A purified column fixing structure including a housing, a connecting groove, a connecting bump, a top block and a through hole is designed, and stable fixation and rapid release of the purified column are achieved through sliding and rotation of the first clamp block and the second clamp block.
This structure improves the stability and safety of the purification column by simplifying fixation operations, is suitable for use in laboratory environments, and can quickly unfix the fixation if needed.
Smart Images
Figure CN222854683U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of purification column fixing, in particular to a purification column fixing structure. Background Art
[0002] Commonly used purification prepacked columns for histone purification include affinity resins, ion exchange resins, hydrophobic chromatography resins and other prepacked columns. The column diameter is mostly 0.5-2 cm, and the column length is usually 1-5 cm. In actual use, the injection end of the prepacked column is connected to the peristaltic pump through a plastic catheter, and the peristaltic pump pumps the solution into the prepacked column. The outlet of the prepacked column is connected to the protein A280 absorption detector through a plastic catheter. After passing through the detector, the solution flows into the protein receiving tube. The prepacked column itself is small in size and needs to be connected between the pump and the protein detector through a catheter. Relevant fixing devices are required to enable it to be placed vertically and stably.
[0003] A purification column fixing bracket on the market has the following disadvantages: common purification column fixing brackets are mostly upper and lower fixed plates, and the purification column is usually directly placed in the card slot. The fixation of the purification column is not stable enough. If it is not aligned during the storage process, the purification column will fall off. At the same time, the existing purification column fixing brackets are mostly an integral body, large in size and fixed, and are not suitable for use in a laboratory environment. Utility Model Content
[0004] The technical problem to be solved by the utility model is that the existing purification column fixing bracket has a single fixing method and is large in size and cannot be adjusted, so it is not suitable for use in a laboratory environment.
[0005] In order to solve the above technical problems, a technical solution adopted by the utility model is: a purification column fixing structure, including a shell, a connection groove is provided on one side surface of the shell, a connection protrusion is fixedly connected to the other side surface of the shell, a top block is fixedly connected to the top of the shell, a through hole is provided in the middle of the shell and the top block, and a purification column is slidably connected to the inner side of the through hole.
[0006] The utility model is further configured as follows: a plurality of first sliding grooves are arranged between the shell and the top block, the plurality of first sliding grooves are symmetrically arranged around the through hole, a plurality of first sliding grooves are slidably connected with first clamping blocks inside, a plurality of adjacent sides of the first clamping blocks are semicircular groove structures, and a rubber pad is fixedly connected to the inner side of the semicircular groove of the first clamping block.
[0007] Through the above technical solution, the purification column can be fixed by placing it into the through hole. At the same time, the first clamping block is provided with a rubber pad to reduce the collision and shaking of the purification column, thereby greatly improving the stability and safety of the fixation.
[0008] The utility model is further configured that a plurality of the first clamping blocks are provided with protrusions on the top ends, the protrusions are slidably connected to the top blocks, the first clamping blocks are fixedly connected with trapezoidal blocks on the bottom ends, the trapezoidal blocks are right-angled trapezoidal structures, the bottom ends of the trapezoidal blocks are inclined ends, and the inclined surfaces of the trapezoidal blocks are provided with second slide grooves.
[0009] The utility model is further configured that a push platform is slidably connected to the middle of the shell, the middle of the push platform is slidably connected to the through hole, both ends of the push platform are connected to the through hole, both ends of the push platform are fixedly connected to sliders, and the slider is slidably connected to the second slide groove.
[0010] Through the above technical solution, the push table moves up and down to pull the first clamp to open and tighten. During use, the purification column is placed in the through hole and pressed downward to achieve the clamping and fixing of the purification column by the first clamp. The purification column can be fixed without extra operations, which greatly simplifies the fixing operation and improves the purification efficiency.
[0011] The utility model is further configured such that a hydraulic telescopic column is fixedly connected to the bottom end of the push platform, the telescopic end of the hydraulic telescopic column is fixedly connected to the push platform, the hydraulic telescopic column is fixedly connected to the shell, and the bottom end of the hydraulic telescopic column is through-connected to the bottom end of the shell.
[0012] Through the above technical solution, when taking out the purification column, it is only necessary to gently lift the purification column, and the push platform moves upward under the push of the hydraulic telescopic column, so that the first clamping block opens and the fixed state is released, which is simple and convenient to operate.
[0013] The utility model is further configured that a rotating shaft is rotatably connected inside the shell, the rotating shaft is located on both sides of the through hole, a connecting rod is fixedly connected to the middle of the rotating shaft, and the rotating shaft is arranged in the middle of the connecting rod.
[0014] The utility model is further configured as follows: one end of the connecting rod is rotatably connected to a second clamping block, the second clamping block is an isosceles trapezoidal structure, the second clamping block is slidably connected to the through hole, the short end of the second clamping block is made of friction material, the second clamping block is arranged with the friction surface facing the inside of the through hole, the end of the connecting rod away from the second clamping block is fixedly connected to a spring, and the spring is fixedly connected to the shell at the end away from the connecting rod.
[0015] Through the above technical solution, when the purification column reaches the bottom of the through hole, the connecting rod rotates under the push of the spring, so that the second clamping block at the other end of the connecting rod is squeezed toward the purification column to fix the bottom of the purification column, thereby greatly improving the stability of the fixation.
[0016] The beneficial effects of the utility model are as follows:
[0017] The utility model can achieve the clamping and fixing of the middle and upper part of the purification column by putting the purification column into the through hole and pressing downwards, and at the same time, when the purification column reaches the bottom of the through hole, the connecting rod rotates under the push of the spring, so that the second clamping block at the other end of the connecting rod is pressed toward the purification column to fix the bottom of the purification column, which greatly improves the stability of the fixation. When the purification column needs to be taken out, it is only necessary to gently lift the purification column, and the push platform moves upwards under the push of the hydraulic telescopic column, so that the first clamping block is opened, the fixing state is released, and the user can pull out the purification column. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 It is a schematic diagram of the overall structure of the utility model;
[0019] Figure 2 It is a three-dimensional schematic diagram of the shell structure of the utility model;
[0020] Figure 3 This is an exploded schematic diagram of the purification column fixing structure of the utility model;
[0021] Figure 4 It is a sectional view of the overall structure of the utility model.
[0022] In the figure: 1, shell; 2, connecting groove; 3, connecting protrusion; 4, top block; 5, purification column; 6, first clamping block; 7, rubber pad; 8, through hole; 9, first slide groove; 10, protrusion; 11, trapezoidal block; 12, second slide groove; 13, slider; 14, push table; 15, hydraulic telescopic column; 16, rotating shaft; 17, connecting rod; 18, second clamping block; 19, spring. DETAILED DESCRIPTION
[0023] The preferred embodiments of the present invention are described in detail below in conjunction with the accompanying drawings so that the advantages and features of the present invention can be more easily understood by those skilled in the art, thereby making a clearer and more definite definition of the protection scope of the present invention.
[0024] See also Figure 1 , Figure 2 , Figure 3 and Figure 4 A purification column fixing structure includes a shell 1, a connection groove 2 is provided on one side surface of the shell 1, a connection protrusion 3 is fixedly connected to the other side surface of the shell 1, a top block 4 is fixedly connected to the top of the shell 1, a through hole 8 is provided in the middle of the shell 1 and the top block 4, and a purification column 5 is slidably connected to the inner side of the through hole 8.
[0025] A plurality of first slide grooves 9 are arranged between the shell body 1 and the top block 4, and the plurality of first slide grooves 9 are symmetrically arranged around the through hole 8. A plurality of first slide grooves 9 are slidably connected inside with a first clamping block 6, and a plurality of adjacent sides of the first clamping blocks 6 are semicircular groove structures. A rubber pad 7 is fixedly connected to the inner side of the semicircular groove of the first clamping block 6. A plurality of first clamping blocks 6 are provided with a protrusion 10 on the top end, and the protrusion 10 is slidably connected with the top block 4. A trapezoidal block 11 is fixedly connected to the bottom end of the first clamping block 6. The trapezoidal block 11 is a right-angled trapezoidal structure, and the bottom end of the trapezoidal block 11 is an inclined end. A second slide groove 12 is provided on the inclined surface of the trapezoidal block 11.
[0026] A push platform 14 is slidably connected to the middle of the shell 1, and the middle of the push platform 14 is slidably connected to the through hole 8. Both ends of the push platform 14 are through-connected with the through hole 8. Slide blocks 13 are fixedly connected to both ends of the push platform 14. The slide block 13 is slidably connected to the second slide groove 12. A hydraulic telescopic column 15 is fixedly connected to the bottom end of the push platform 14. The telescopic end of the hydraulic telescopic column 15 is fixedly connected to the push platform 14, and the hydraulic telescopic column 15 is fixedly connected to the shell 1, and the bottom end of the hydraulic telescopic column 15 is through-connected with the bottom end of the shell 1.
[0027] A rotating shaft 16 is rotatably connected inside the shell 1, and the rotating shaft 16 is located on both sides of the through hole 8. A connecting rod 17 is fixedly connected to the middle of the rotating shaft 16. The rotating shaft 16 is arranged in the middle of the connecting rod 17. One end of the connecting rod 17 is rotatably connected to a second clamping block 18. The second clamping block 18 is an isosceles trapezoidal structure. The second clamping block 18 is slidably connected to the through hole 8. The short end of the second clamping block 18 is made of friction material, and the second clamping block 18 is arranged to face the friction surface inside the through hole 8. A spring 19 is fixedly connected to the end of the connecting rod 17 away from the second clamping block 18, and the end of the spring 19 away from the connecting rod 17 is fixedly connected to the shell 1.
[0028] When the utility model is in use, the required fixing structure can be installed according to actual needs through the connecting groove 2 and the connecting protrusion 3 on the surface of the shell 1, and it can be made into a whole. During use, the purification column 5 is placed in the through hole 8, and the first clamping block 6 can be pressed downward to clamp and fix the upper and middle parts of the purification column 5. At the same time, when the purification column 5 reaches the bottom of the through hole 8, the connecting rod 17 rotates under the push of the spring 19, so that the second clamping block 18 at the other end of the connecting rod 17 is pressed toward the purification column 5 to fix the bottom of the purification column 5, which greatly improves the stability of the fixation. When the purification column 5 needs to be taken out, it is only necessary to gently lift the purification column 5, and the push platform 14 moves upward under the push of the hydraulic telescopic column 15, so that the first clamping block 6 is opened, the fixed state is released, and the user can pull out the purification column 5. Therefore, the present fixing structure can fix the purification column 5 without unnecessary operation, which greatly simplifies the fixing operation and improves the purification efficiency.
[0029] The above are only embodiments of the present invention, and are not intended to limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made using the contents of the specification and drawings of the present invention, or directly or indirectly applied in other related technical fields, are also included in the patent protection scope of the present invention.
Claims
1. A purification column fixing structure, comprising a housing (1), characterized in that: A connection groove (2) is provided on one side surface of the shell (1), a connection protrusion (3) is fixedly connected to the other side surface of the shell (1), a top block (4) is fixedly connected to the top of the shell (1), a through hole (8) is provided in the middle of the shell (1) and the top block (4), and a purification column (5) is slidably connected to the inner side of the through hole (8); A plurality of first slide grooves (9) are arranged between the shell (1) and the top block (4), the plurality of first slide grooves (9) are symmetrically arranged around the through hole (8), a plurality of first slide grooves (9) are slidably connected to first clamping blocks (6) inside, a plurality of adjacent sides of the first clamping blocks (6) are semicircular groove structures, and a rubber pad (7) is fixedly connected to the inner side of the semicircular groove of the first clamping block (6); A plurality of the first clamping blocks (6) are provided with protrusions (10) at the top ends thereof, the protrusions (10) being slidably connected to the top block (4), the bottom ends of the first clamping blocks (6) being fixedly connected to a trapezoidal block (11), the trapezoidal block (11) being a right-angled trapezoidal structure, the bottom ends of the trapezoidal blocks (11) being an inclined end, and the inclined surfaces of the trapezoidal blocks (11) being provided with second slide grooves (12); The middle of the shell (1) is slidably connected to a push platform (14), the middle of the push platform (14) is slidably connected to the through hole (8), both ends of the push platform (14) are connected to the through hole (8), both ends of the push platform (14) are fixedly connected to sliders (13), and the sliders (13) are slidably connected to the second slide groove (12).
2. A purification column fixing structure according to claim 1, characterized in that: The bottom end of the push platform (14) is fixedly connected to a hydraulic telescopic column (15); the telescopic end of the hydraulic telescopic column (15) is fixedly connected to the push platform (14); the hydraulic telescopic column (15) is fixedly connected to the housing (1); and the bottom end of the hydraulic telescopic column (15) is connected through the bottom end of the housing (1).
3. A purification column fixing structure according to claim 1, characterized in that: A rotating shaft (16) is rotatably connected inside the housing (1), the rotating shaft (16) is located on both sides of the through hole (8), a connecting rod (17) is fixedly connected to the middle of the rotating shaft (16), and the rotating shaft (16) is arranged in the middle of the connecting rod (17).
4. A purification column fixing structure according to claim 3, characterized in that: One end of the connecting rod (17) is rotatably connected to a second clamping block (18); the second clamping block (18) is an isosceles trapezoidal structure; the second clamping block (18) is slidably connected to the through hole (8); the short end of the second clamping block (18) is made of friction material; the second clamping block (18) is arranged to face the friction surface and is disposed inside the through hole (8); one end of the connecting rod (17) away from the second clamping block (18) is fixedly connected to a spring (19); and one end of the spring (19) away from the connecting rod (17) is fixedly connected to the housing (1).