Special rotary flow type gas-liquid-solid three-phase mixer for fermentation tank

Abstract

The utility model discloses a rotating flow type gas-liquid-solid three-phase mixer special for a fermentation tank, and relates to the technical field of mixers. The device comprises a necking liquid inlet, a mixing pipe, a diffuser pipe and a rotary vane, the fixed rib plate is arranged around the periphery of the liquid inlet, the air inlet pipe extends into the liquid inlet, and a conical nozzle is arranged at the front end of the air inlet pipe; the tail end of the side wall of the rotary vane is fixedly connected with the inner wall of the mixing pipe by spot welding; according to the technical scheme, the rotary vane is of an equal-diameter spiral structure which is vertically arranged; compressed air passes through a nozzle high-speed flow, static pressure energy is converted into kinetic energy, collision crushing is achieved, and kinetic energy maximization of three-phase flow is achieved under the constraint of a mixing pipe; the required scale of bubble breaking is realized; sufficient transfer of momentum is completed at an outlet of the diffuser pipe; the mixture subjected to bubble breaking flows through an outlet of the diffuser pipe, and power of the mixture and the fermentation liquor which does not pass through the three-phase mixer is fully transmitted; under the condition that shear stress is fully met, flux is maximized, energy loss is minimized, and energy consumption corresponding to stirring is greatly reduced.

Description

Technical Field

[0001] The utility model belongs to the technical field of mixers, in particular to a rotary flow type gas-liquid-solid three-phase mixer special for a fermentation tank. Background Art

[0002] Almost all domestic fermentation industries such as antibiotics, vitamins, amino acids, and organic acids use ventilated stirred reactors for industrial production. Fermentation equipment has always had the problem of large energy waste in the fermentation process, high energy consumption, and low ventilation utilization rate.

[0003] Restricted by engineering level, traditional stirred aeration fermentation reactors have significantly restricted the progress of fermentation. With the development of engineered bacteria and the advancement of synthetic biology, aeration fermentation characterized by high-density fermentation of Escherichia coli, Bacillus subtilis and yeast has higher and higher requirements for engineering level, and traditional stirred aeration reactors are becoming more and more constrained.

[0004] In the application of high mass transfer circulating fermenters and self-mixing circulating fermenters and the practical promotion of various products, the key technology is the need to control ventilation, among which the mixer is the key component for controlling ventilation; the general ventilation fermenter stirring system in the prior art has multi-layer blades, and the bottom blades are turbine radial flow stirring. The bottom radial flow stirring energy consumption is generally designed to account for 60% of the total stirring power, and the middle and upper parts are multi-layer open axial flow mixing slurry, and the stirring energy consumption is relatively high; the present technical scheme provides a special rotary flow gas-liquid-solid three-phase mixer for fermenters, which can replace the original bottom radial flow stirring, and achieve huge energy-saving effects, can complete series standardization and has strong shear mixing and mass transfer characteristics. Utility Model Content

[0005] The utility model provides a special rotary flow gas-liquid-solid three-phase mixer for a fermentation tank, which is composed of a liquid inlet, a mixing tube, a diffuser, an air inlet pipe and a rotor arranged in the mixing tube for guiding the angular flow of a high-speed mixed flow. The end of the side wall of the rotor is fixedly connected to the inner wall of the mixing tube by spot welding, and the rotor is a spiral structure of equal diameter arranged vertically; the compressed air passes through the nozzle at a high speed to convert static pressure energy into kinetic energy, realizes collision crushing, and the three-phase flow realizes kinetic energy maximization under the constraint of the mixing tube; the three-phase flow rotates with the angle of the rotor, and the gas, liquid and solid densities are different. In the process of constantly changing directions, sufficient mixing is achieved, and the continuous mixing process realizes continuous bubble crushing, and the required scale of bubble crushing is achieved on the basis of ensuring that the mycelium is intact; the momentum is fully transferred at the outlet of the diffuser; the mixed flow that completes the bubble crushing passes through the outlet of the diffuser, and completes the full power transfer with the fermentation liquid that has not passed through the three-phase mixer; the structure of the technology can maximize the flux and minimize the energy loss under the condition of fully satisfying the shear stress, and the energy consumption corresponding to the stirring is greatly reduced; in summary, the problems in the background technology are solved.

[0006] In order to solve the above technical problems, the utility model is realized by the following technical solutions:

[0007] The utility model discloses a special rotary flow gas-liquid-solid three-phase mixer for a fermentation tank, comprising a contracted liquid inlet, a mixing tube connected to the smaller diameter end of the liquid inlet, a diffuser connected to the end of the mixing tube, an air inlet pipe fixedly installed by a fixed rib plate, and a rotary vane arranged in the mixing tube for guiding the high-speed mixed flow at an angle;

[0008] The fixed ribs are arranged around the liquid inlet, the air inlet pipe extends into the liquid inlet and a conical nozzle is arranged at the front end;

[0009] The end of the side wall of the rotary vane is fixedly connected to the inner wall of the mixing tube by spot welding.

[0010] Furthermore, the diffuser pipe, mixing pipe, conical nozzle and air inlet pipe are coaxially arranged.

[0011] Furthermore, the rotary vane is a vertically arranged spiral structure with equal diameter.

[0012] Furthermore, the mixing tube is a tube of equal diameter; the small diameter end of the diffuser tube and the small diameter end of the liquid inlet have the same diameter as the mixing tube.

[0013] Furthermore, the diffuser tube adopts an outward-expanding conical structure.

[0014] Compared with the prior art, the utility model has the following beneficial effects:

[0015] (1) The special rotary flow gas-liquid-solid three-phase mixer for the fermentation tank comprises a liquid inlet, a mixing tube, a diffuser tube, and a rotor installed in the mixing tube for guiding the high-speed mixed flow at an angle. The rotor adopts a vertically arranged equal-diameter spiral structure; the compressed air flows through the nozzle at a high speed to convert static pressure energy into kinetic energy, realizes collision and crushing, and the three-phase flow realizes kinetic energy maximization under the constraint of the mixing tube;

[0016] (2) As the three-phase flow rotates with the vane angle, the gas, liquid and solid densities are different. In the process of constantly changing direction, sufficient mixing is achieved. The continuous mixing process realizes the continuous breaking of bubbles. On the basis of ensuring the integrity of the mycelium, the required scale of bubble breaking is achieved; the momentum is fully transferred at the outlet of the diffuser;

[0017] (3) The mixed flow after bubble crushing passes through the outlet of the diffuser, completing the full power transfer with the fermentation liquid that has not passed through the three-phase mixer;

[0018] (4) The structure of this technology can maximize the flux and minimize the energy loss under the condition of fully satisfying the shear stress, which greatly reduces the energy consumption corresponding to stirring.

[0019] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0021] Figure 1 This is a structural schematic diagram of a rotary flow type gas-liquid-solid three-phase mixer specially used for a fermentation tank of the utility model;

[0022] Figure 2 for Figure 1 A top view of the structure;

[0023] Figure 3 for Figure 1 Bottom view of the structure;

[0024] Figure 4 for Figure 1 Schematic diagram of the structure of the mixing tube;

[0025] Figure 5 for Figure 1 Schematic diagram of the structure of the middle rotary blade;

[0026] Figure 6 for Figure 1 Schematic diagram of the structure of the fixed rib plate;

[0027] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0028] 1-air inlet pipe, 11-conical nozzle, 12-fixed rib, 2-liquid inlet, 3-mixing tube, 31-diffuser, 4-rotor vane. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0030] In the description of the present invention, it is necessary to understand that the terms "one end", "end", "circumferential side", "side wall", "bottom" and the like indicating orientation or positional relationship are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the components or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0031] Almost all domestic fermentation industries such as antibiotics, vitamins, amino acids, and organic acids use universal ventilation stirring reactor technology for industrial product production. The domestic large-scale fermentation industry has been in operation for more than 60 years, but there has been no major breakthrough in fermentation equipment. The fermentation process has always been characterized by large energy waste, high energy consumption, and low ventilation oxygen utilization.

[0032] In recent years, with the progress in the strains and processes of various fermentation products, the fermentation level has been greatly improved; there have been certain breakthroughs at the molecular and cellular levels, but due to the constraints of engineering level, the traditional stirred and ventilated fermentation reactor has obviously restricted the progress of fermentation; with the development of engineered bacteria and the progress of synthetic biology, the ventilation fermentation characterized by high-density fermentation of Escherichia coli, Bacillus subtilis and yeast has higher and higher requirements on the engineering level, and the traditional stirred and ventilated reactor is becoming more and more constrained.

[0033] The key technology of fermentation tank is to control ventilation, among which the mixer is the key component of controlling ventilation. It is necessary to continuously develop three-phase mixers with new suitability according to the differences in shear stress requirements of different bacterial genera of different fermentation products to achieve the de-agitation of the fermentation reactor. This technical solution proposes a rotary flow gas-liquid-solid three-phase mixer specially used for fermentation tanks, and completes series standardization. This series of three-phase mixers has the mixing and mass transfer characteristics of intense impact shear, and is suitable for bacterial fermentation.

[0034] In the ventilated aerobic fermentation industry, the general ventilated fermentation tank stirring system has multiple layers of blades, and the bottom blades are turbine radial flow stirring. The bottom radial flow stirring energy consumption is generally designed to account for 60% of the total stirring power, and the middle and upper parts are multi-layer open axial flow mixed slurry; the high mass transfer circulation fermenter and self-mixing circulation fermenter developed in this scheme are both non-stirring energy-saving fermenters, and the gas-liquid-solid three-phase mixer replaces the bottom radial flow stirring to achieve huge energy-saving effects.

[0035] See also Figure 1-6 As shown, the utility model is a special rotary flow gas-liquid-solid three-phase mixer for a fermentation tank, comprising a contracted liquid inlet 2, a mixing tube 3 connected to the smaller diameter end of the liquid inlet 2, a diffuser 31 connected to the end of the mixing tube 3, an air inlet pipe 1 fixedly installed by a fixed rib plate 12, and a rotor 4 arranged in the mixing tube 3 for guiding the high-speed mixed flow at an angle;

[0036] The fixed ribs 12 are arranged around the liquid inlet 2, the air inlet pipe 1 extends into the liquid inlet 2 and a conical nozzle 11 is arranged at the front end;

[0037] The end of the side wall of the rotary vane 4 is fixedly connected to the inner wall of the mixing tube 3 by spot welding.

[0038] The diffuser pipe 31, the mixing pipe 3, the conical nozzle 11 and the air inlet pipe 1 are coaxially arranged.

[0039] The rotating blade 4 is a vertically arranged spiral structure with equal diameter.

[0040] The mixing tube 3 is a tube of equal diameter; the small diameter end of the diffuser tube 31 and the small diameter end of the liquid inlet 2 have the same diameter as the mixing tube 3 .

[0041] The diffuser tube 31 adopts an outward-expanding conical structure.

[0042] The specific application of this technical solution is:

[0043] According to the basic information parameters of the fermentation product, complete the design calculation of the three-phase mixer, determine the quantity and specifications, and arrange the air inlet pipe network at the bottom of the fermentation tank;

[0044] The rotary flow gas-liquid-solid three-phase mixer is divided into a mixer air inlet pipe, a conical nozzle, a mixer liquid inlet, a mixing tube, a rotor, and a diffuser. A special nozzle is welded to the mixer air inlet pipe, the air inlet pipe and the liquid inlet are positioned using a special positioning mold and welded and connected with fixed-length ribs, the liquid inlet is connected to the mixing tube, the mixing tube has a built-in rotor, and the mixing tube is connected to the diffuser.

[0045] The mixer is placed at the bottom of the fermentation tank and immersed in the deep liquid and solid. Air enters from the air inlet pipe of the mixer and flows through the nozzle at high speed, realizing the conversion of static pressure energy into kinetic energy to form a negative pressure area. The pressure difference presses the fermentation liquid from the liquid inlet of the mixer into the mixer. The high-speed mixed flow flows along the guide angle of the rotor and changes direction by rotation to continuously strengthen the three-phase mixing of gas, liquid and solid. The mixing process is the process of continuous breaking of bubbles. The shear stress is different when the rotation angle is different to meet the needs of culturing various bacterial genera. The gas-liquid-solid three-phase mixed flow flows out of the diffuser, which can fully complete the momentum transfer with the fermentation liquid in the tank.

[0046] The general ventilation stirred fermenter used for filamentous bacteria fermentation has three shortcomings: rigid shear damage, nucleic acid leakage, and plasmid leakage. When frequency conversion is used to reduce shear, there is a mismatch between the stirring input work and the ventilation expansion work, resulting in serious gas flooding and a significant reduction in efficiency. The fermentation-specific rotary flow gas-liquid-solid three-phase mixer can be designed to meet the appropriate shear stress requirements for different fermentation products.

[0047] Basic principle of mixer:

[0048] 1. Compressed air flows through the nozzle at high speed to convert static pressure energy into kinetic energy, achieving collision and crushing;

[0049] 2. The three-phase flow achieves maximum kinetic energy under the constraints of the mixing tube;

[0050] 3. As the three-phase flow rotates with the vane angle, the gas, liquid and solid densities are different. In the process of constantly changing direction, sufficient mixing is achieved. The continuous mixing process causes the bubbles to be continuously broken, ensuring the integrity of the mycelium and achieving the required scale of bubble breaking.

[0051] 4. The momentum is fully transferred at the diffuser outlet.

[0052] In the experimental tank device, under the conditions of constant air volume, constant temperature and constant pressure, the sodium sulfite solution oxidation experiment was carried out to determine the mixer performance; DO (dissolved oxygen) and tail gas oxygen concentration were continuously determined, and the continuous characteristic curve of the rotating flow gas-liquid-solid three-phase mixer was drawn, as well as curves such as KLa, OTR (oxygen supply), DO, tail gas oxygen concentration, sodium sulfite consumption rate and oxygen utilization rate; liquid-gas ratio detection was completed on a special liquid-gas ratio detection device, and gas content detection was completed on a gas content experimental device. The biggest feature is that bubble fragmentation is gradually achieved under mild conditions, which is suitable for the fermentation engineering conditions of actinomycete antibiotics and further broadens the scope of use of fermentation products.

[0053] The preferred embodiments of the utility model disclosed above are only used to help explain the utility model. The preferred embodiments do not describe all the details in detail, nor do they limit the utility model to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the utility model, so that technicians in the relevant technical field can well understand and use the utility model. The utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A rotary flow gas-liquid-solid three-phase mixer for a fermentation tank, characterized in that: It comprises a contracted liquid inlet (2), a mixing tube (3) connected to the smaller diameter end of the liquid inlet (2), a diffuser tube (31) connected to the end of the mixing tube (3), an air inlet tube (1) fixedly mounted via a fixed rib plate (12), and a rotor (4) arranged in the mixing tube (3) for guiding the high-speed mixed flow at an angle; The fixed rib plate (12) is arranged around the liquid inlet (2), the air inlet pipe (1) extends into the liquid inlet (2) and a conical nozzle (11) is provided at the front end; The end of the side wall of the rotary vane (4) is fixedly connected to the inner wall of the mixing tube (3) by spot welding.

2. A rotary flow gas-liquid-solid three-phase mixer for a fermentation tank according to claim 1, characterized in that: The diffuser pipe (31), the mixing pipe (3), the conical nozzle (11) and the air inlet pipe (1) are arranged coaxially.

3. The rotary flow gas-liquid-solid three-phase mixer for fermentation tank according to claim 1, characterized in that: The rotary blade (4) is a vertically arranged spiral structure with equal diameter.

4. The rotary flow gas-liquid-solid three-phase mixer for fermentation tank according to claim 1, characterized in that: The mixing tube (3) is a tube of equal diameter; the small diameter end of the diffuser tube (31) and the small diameter end of the liquid inlet (2) have the same diameter as the mixing tube (3).

5. The rotary flow gas-liquid-solid three-phase mixer for fermentation tank according to claim 1, characterized in that: The diffuser tube (31) adopts an outward-expanding conical structure.

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