Reagent preparation equipment
By designing a reagent configuration device including liquid storage tube, conduit and switch, the problem of artificial inaccurate operation during reagent configuration is solved, and the precise control of liquid volume and the efficiency and accuracy of reagent configuration are achieved.
Patent Information
- Application Number
- CN202421861416.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-01
- Publication Date
- 2025-05-13
- Estimated Expiration
- 2034-08-01
AI Technical Summary
In medical testing, errors are easily introduced during the reagent configuration due to inaccurate human operations, resulting in inaccurate reagent configuration.
A reagent configuration device is designed, including a liquid storage tube, a conduit, a first switch and a second switch. The liquid volume of the liquid to be fused is detected through the conduit, and the precise configuration of the liquid is achieved through the control of the first switch and the second switch.
Accurate control of the volume of the liquid treated with the fusion liquid is achieved, reducing the error of artificial operation, and improving the accuracy and efficiency of reagent configuration.
Smart Images

Figure CN222855184U_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the field of medical testing technology, and in particular to a reagent configuration device. Background Art
[0002] In medical tests, accurate and efficient configuration of experimental reagents is a key link to ensure accurate experimental results. In the daily process of configuring reagents, the technicians of the test need to manually operate the pipette to draw different volumes of liquid components from multiple containers storing the liquids to be fused, and add them to the test tubes used for the reaction in sequence to obtain the experimental reagents. Due to the limited volume of the pipette, when large volumes of reagents or high-precision reagents need to be configured, the technicians need to frequently open the containers, draw, and transfer different liquids to be fused, which significantly increases the number of pipetting times. Moreover, the pipetting is completely dependent on the technicians' memory and manual operation, which is very easy to introduce errors due to human negligence (such as misremembering the component name, volume or number of times), resulting in inaccurate reagent configuration. Utility Model Content
[0003] The embodiment of the present application discloses a reagent configuration device, which realizes precise control of the liquid volume corresponding to the liquid to be fused, thereby ensuring the accuracy of the reagent configuration.
[0004] In a first aspect, an embodiment of the present application discloses a reagent configuration device, comprising:
[0005] N liquid storage tubes, used to store different liquids to be fused; N is an integer greater than 1;
[0006] N catheters, the catheters are used to store the liquid to be fused, and detect the liquid volume corresponding to the liquid to be fused stored in the catheters;
[0007] N first switches, the N first switches corresponding one-to-one to the N liquid storage tubes and one-to-one to the N conduits, the first switches being connected to the corresponding liquid storage tubes and to the first ends of the corresponding conduits;
[0008] a second switch connected to second ends of the N conduits;
[0009] a fusion part, the fusion part being connected to the second switch; the fusion part being used for merging the liquid to be fused flowing from the N conduits to the fusion part;
[0010] When the first switch is turned on, the liquid to be fused in the liquid storage tube connected to the first switch flows to the catheter connected to the first switch; when the first catheter detects that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the first switch connected to the first catheter is turned off; the first catheter is any of the catheters;
[0011] When the N conduits respectively detect that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the second switch is turned on to allow the liquid to be fused respectively stored in the N conduits to flow into the fusion part.
[0012] As an optional embodiment, in the first aspect of the embodiment of the present application, the first switch includes a switch element and a flow sensor, and the flow sensor is used to detect the liquid volume corresponding to the liquid to be fused flowing from the liquid storage tube connected to the first switch to the catheter; when the first flow sensor detects that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the first switch corresponding to the first flow sensor is closed; the first flow sensor is a flow sensor corresponding to any first switch.
[0013] As an optional implementation, in the first aspect of the embodiment of the present application, the liquid outlet of the fusion part is connected to a reagent container, and the reagent container is used to store the fusion liquid obtained by liquid fusion of the fusion part.
[0014] As an optional implementation, in the first aspect of the embodiment of the present application, a concentration sensor is provided on the reagent container, and the concentration sensor is used to detect the liquid concentration corresponding to the fusion liquid stored in the reagent container.
[0015] As an optional implementation, in the first aspect of the embodiment of the present application, a volume sensor is provided on the reagent container, and the volume sensor is used to detect the liquid volume corresponding to the fusion liquid stored in the reagent container.
[0016] As an optional implementation, in the first aspect of the embodiment of the present application, the reagent preparation device also includes a stirring tool, and the stirring tool is arranged in the fusion part, and the stirring tool is used to stir the N kinds of liquids to be fused in the fusion part.
[0017] As an optional implementation, in the first aspect of the embodiment of the present application, the N liquid storage tubes are respectively detachably connected to the corresponding first switches.
[0018] As an optional implementation, in the first aspect of the embodiment of the present application, the reagent configuration device also includes a control module, and the control module is used to control the N first switches to be turned on or off; and control the second switch to be turned on or off.
[0019] As an optional implementation, in a first aspect of the embodiment of the present application, the catheter includes a curved section, and a corresponding bending angle of the curved section is greater than 90 degrees.
[0020] As an optional implementation, in the first aspect of the embodiment of the present application, the reagent configuration device also includes a touch display panel, which is used to display configuration information and touch controls; the configuration information includes parameter information of the liquid to be fused during the reagent configuration process; and the touch controls are used to trigger the reagent configuration device to start the reagent configuration process.
[0021] The reagent configuration device disclosed in the embodiment of the present application includes: N liquid storage tubes, used to store different liquids to be fused; N is an integer greater than 1; N catheters, the catheters are used to store the liquids to be fused, and detect the liquid volume corresponding to the liquids to be fused stored in the catheters; N first switches, the N first switches correspond one-to-one to the N liquid storage tubes, and correspond one-to-one to the N catheters, the first switches are connected to the corresponding liquid storage tubes, and are connected to the first ends of the corresponding catheters; the second switch, the second switch is connected to the second ends of the N catheters; a fusion part, the fusion part is connected to the second switch; the fusion part is used to fuse the liquids to be fused flowing from the N catheters to the fusion part. In the embodiment of the present application, the liquid volumes of the liquids to be fused are respectively detected by N catheters, so that the opening and closing of the first switch connected to the catheter can be accurately controlled to obtain N types of liquids to be fused with the same liquid volumes as the corresponding configuration volumes. Since the N types of liquids to be fused independently correspond to a liquid storage tube, a first switch and a catheter, the N catheters can store the liquids to be fused and measure the liquid volumes at the same time, which improves the efficiency of reagent configuration, and can achieve accurate measurement and control of various liquids to be fused, which can reduce errors that may be caused by human operation and improve the accuracy and efficiency of reagent configuration. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0023] Figure 1 A schematic diagram of the structure of a reagent configuration device in one embodiment;
[0024] Figure 2 is a schematic diagram of the structure of a catheter in one embodiment;
[0025] Figure 3 is a schematic structural diagram of a fusion portion in an embodiment;
[0026] Figure 4 is a schematic structural diagram of a reagent container in one embodiment;
[0027] Figure 5It is a structural schematic diagram of a reagent configuration device in another embodiment;
[0028] Figure 6 A flow chart of configuring reagents for a reagent configuration device in one embodiment. DETAILED DESCRIPTION
[0029] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.
[0030] It should be noted that the terms "including" and "having" and any variations thereof in the embodiments of the present application and the accompanying drawings are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device including a series of steps or units is not limited to the listed steps or units, but may optionally include steps or units not listed, or may optionally include other steps or units inherent to these processes, methods, products or devices.
[0031] It is understood that the terms "first", "second", etc. used in this application may be used herein to describe various elements, but these elements are not limited by these terms. These terms are only used to distinguish a first element from another element. For example, without departing from the scope of this application, a first switch may be referred to as a second switch, and similarly, a second switch may be referred to as a first switch. Both the first switch and the second switch are switches, but they are not the same switches.
[0032] The embodiment of the present application discloses a reagent configuration device, which realizes precise control of the liquid volume corresponding to the liquid to be fused, thereby ensuring the accuracy of the reagent configuration.
[0033] Figure 1 FIG. 1 is a schematic diagram of the structure of a reagent configuration device in one embodiment. Figure 1 As shown, in one embodiment, the reagent configuration device 100 may include one or more of the following components: N liquid storage tubes 110, N first switches 120, N conduits 130, a second switch 140, and a fusion portion 150. Wherein, N is an integer greater than 1.
[0034] In the embodiment of the present application, the N first switches 120 correspond one-to-one to the N liquid storage tubes 110, and correspond one-to-one to the N conduits 130; the first switches 120 are connected to the corresponding liquid storage tubes 110, and are connected to the first ends of the corresponding conduits 130. The second switches 140 are respectively connected to the second ends of the N conduits 130. The fusion part 150 is connected to the second switches 140.
[0035] The N liquid storage tubes 110 are used to store different liquids to be fused; the catheter 130 may be a catheter with a liquid volume sensing function, the catheter 130 is used to store the liquid to be fused and detect the liquid volume corresponding to the liquid to be fused stored in the catheter 130; the fusion part 150 is used to fuse the liquid to be fused flowing from the N catheters 130 to the fusion part 150.
[0036] Optionally, the N liquid storage tubes 110 are respectively detachably connected to the corresponding first switches 120 .
[0037] Furthermore, since the liquid has gravity, when the first switch 120 is turned on, the liquid to be fused in the liquid storage tube 110 connected to the first switch 120 flows to the conduit 130 connected to the first switch 120; and, when the first conduit 130 detects that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the first switch 120 connected to the first conduit 130 is closed; the first conduit 130 is any conduit 130.
[0038] In some embodiments, when the liquid storage tube 110 transfers the liquid to be fused to the catheter 130, that is, when any one of the N first switches 120 is turned on, the second switch 140 can be turned off; when the N catheters 130 respectively detect that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the N first switches 120 are all turned off and the second switch 140 is turned on, so that the liquid to be fused stored in the N catheters 130 respectively flows into the fusion part 150.
[0039] The second switch 140 is turned on only when the volumes of N kinds of liquids in the N tubes 130 are the same as the corresponding configured volumes of the liquid to be fused. This can prevent the liquid to be fused in the tubes 130 from flowing toward the fusion part 150 while the liquid to be fused is still flowing from the liquid storage tube 110 to the tubes 130, resulting in inaccurate liquid volume detected by the tubes 130, thereby affecting the accuracy of the reagent configuration.
[0040] The reagent configuration device in the embodiment of the present application can detect the liquid volume of the liquid to be fused respectively through N catheters, so as to accurately control the opening and closing of the first switch connected to the catheter to obtain N types of liquids to be fused with the same liquid volume as the corresponding configuration volume. Since the N types of liquids to be fused independently correspond to a liquid storage tube, a first switch and a catheter, the N catheters can store the liquids to be fused and measure the liquid volume at the same time, which improves the efficiency of reagent configuration, and can realize accurate measurement and control of various liquids to be fused, which can reduce the errors that may be caused by human operation and improve the accuracy and efficiency of reagent configuration.
[0041] In some embodiments, the first switch 120 of the reagent preparation device 100 includes a switch element and a flow sensor, and the flow sensor is used to detect the liquid volume corresponding to the liquid to be fused flowing from the liquid storage tube 110 connected to the first switch 120 to the conduit 130. The switch element can be used to control the on and off of the flow of the liquid to be fused.
[0042] Optionally, in order to prevent the liquid to be fused from flowing back from the conduit 130 into the liquid storage tube 110 and affecting the detection of the flow sensor, the switch element in the first switch 120 of the reagent configuration device 100 can be set as a liquid control element with anti-backflow function such as a one-way valve.
[0043] Specifically, when the switch element of the first switch 120 is turned on, the liquid to be fused stored in the liquid storage tube 110 connected to the first switch 120 flows through the first flow sensor of the first switch 120, flows into and is stored in the conduit 130 connected to the first switch 120. At this time, the first flow sensor of the first switch 120 can collect the liquid volume corresponding to the liquid to be fused flowing through the first flow sensor in real time. When the first flow sensor detects that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the first switch 120 corresponding to the first flow sensor is turned off, that is, the switch element of the first switch 120 is turned off; the first flow sensor is a flow sensor corresponding to any first switch 120.
[0044] Optionally, the flow sensor can calculate the volume of the liquid to be fused by detecting physical changes (such as temperature changes, mechanical displacement, etc.) generated when the liquid to be fused flows through the sensor.
[0045] In some embodiments, in order for the flow sensor to better detect the liquid volume corresponding to the liquid to be fused flowing from the liquid storage tube 110 to the catheter 130, the first switch 120 of the reagent configuration device 100 may also include a flow control device, which is used to control the flow rate or flow velocity of the liquid to be fused flowing from the liquid storage tube 110 to the catheter 130, so that the flow sensor can obtain a more accurate liquid volume, thereby making the configured reagent more accurate.
[0046] In a further embodiment, Figure 2 FIG. 1 is a schematic diagram of the structure of the catheter 130 in one embodiment.
[0047] In some embodiments, the catheter 130 may include a first end 131 , a second end 132 , and a curved section 133 , wherein the first end 131 is used to connect to the first switch 120 corresponding to the catheter 130 ; and the second end 132 is used to connect to the second switch 140 .
[0048] Specifically, the conduits 130 are all made of smooth materials to prevent the liquid to be fused from remaining on the tube wall and affecting the detection of the liquid volume. Since the flow of the liquid to be fused is based on the gravity of the liquid to be fused, in order to ensure that the liquid to be fused in the liquid storage tube 110 can flow smoothly into the conduit 130, and the liquid to be fused in the conduit 130 can flow smoothly into the fusion part 150, the bending angle β corresponding to the curved section 133 of the conduit 130 is greater than 90 degrees, and β needs to be less than 180 degrees, so as to form an arc curve with the center of the circle upward. In addition, the appearance of the conduit 130 can also adopt a smooth curve design, which can further reduce the resistance of the liquid to be fused during the flow process, so that the liquid to be fused can flow smoothly into the conduit 130 or out of the conduit 130, and reduce the liquid residue in the curved section 133 or the connection.
[0049] In some embodiments, the conduit 130 may be provided with a volume sensor, and the conduit 130 may detect the liquid volume of the liquid to be fused stored in the conduit 130 through the volume sensor. Optionally, the conduit 130 may be provided with a float sensor for detecting the position of the liquid level in the conduit 130, and the conduit 130 may calculate the liquid volume corresponding to the liquid to be fused in the conduit 130 by detecting the proportional relationship between the level of the liquid to be fused in the conduit 130 and the preset length of the conduit 130.
[0050] In some embodiments, since there is a one-to-one correspondence between the liquid storage tube 110 storing the liquid to be fused, the first switch 120 and the conduit 130, the N first switches 120 of the reagent configuration device 100 can be turned on at the same time, so that the N liquids to be fused start to flow to the corresponding conduits 130 at the same time. Compared with manually transferring the liquids to be fused one by one through a pipette, the reagent configuration device 100 in the embodiment of the present application can measure the N liquids to be fused in a parallel processing manner, shorten the total time of reagent configuration, and improve the efficiency of reagent configuration, especially when multiple reagents need to be configured at the same time or the target volume corresponding to the target reagent is large, the waiting time can be greatly shortened to meet the demand for rapid configuration of reagents.
[0051] In a further embodiment, Figure 3 FIG. 1 is a schematic diagram of the structure of the fusion portion 150 in an embodiment.
[0052] In some embodiments, the fusion part 150 may include a liquid inlet 151, a liquid outlet 152 and a stirring tool 153. The liquid inlet 151 is used to connect with the second switch 140; the liquid outlet 152 is used to connect with the reagent container 160, and the reagent container 160 is used to store the fusion liquid obtained by the fusion of the liquids in the fusion part 150; the stirring tool 153 is disposed in the fusion part 150, and the stirring tool 153 is used to stir the N kinds of liquids to be fused in the fusion part 150.
[0053] Optionally, the fusion of liquids in the fusion section 150 may refer to the mixing of N liquids to be fused; or may refer to the biochemical reaction of N liquids to be fused.
[0054] Exemplarily, after the second switch 140 is turned on, the liquids to be fused respectively stored in the N conduits 130 begin to gradually flow into the fusion section 150. At the same time, the stirring tool 153 in the fusion section 150 is started to stir the N liquids to be fused flowing toward the fusion section 150, so that the stirring tool 153 then carefully stirs the N liquids to be fused that have flowed toward or are flowing toward the fusion section 150, thereby causing these liquids to be fused to reach a more uniform mixing state at the molecular level through physical action.
[0055] Optionally, the stirring tool 153 can be a physical stirring rod, a magnetic stirring bar, a gas stirring device (such as inert gas such as nitrogen, argon, etc.), etc.
[0056] In some embodiments, in order to prevent the liquid to be fused from corroding the inner wall of the liquid storage tube 110 and the conduit 130 when flowing through the liquid storage tube 110 and the conduit 130, thereby affecting the accuracy of the data, the reagent configuration device 100 may include a self-cleaning module. The self-cleaning module can be used to self-clean and disinfect the reagent configuration device 100 after completing the reagent configuration and / or before starting the configuration, thereby restoring the original state of each component of the reagent configuration device 100, reducing the flow resistance of the liquid to be fused, and improving the fluid transmission efficiency, so as to improve the reagent configuration efficiency.
[0057] In a further embodiment, Figure 4 FIG. 1 is a schematic diagram of the structure of a reagent container 160 in one embodiment.
[0058] In some embodiments, the reagent container 160 may include a liquid inlet 161, a concentration sensor 162, and a volume sensor 163. The liquid inlet 161 of the reagent container 160 is connected to the liquid outlet 152 of the fusion part 150, so that the fused liquid obtained by the liquid fusion flowing through the fusion part 150 flows into the reagent container 160; the concentration sensor 162 is used to detect the liquid concentration corresponding to the fused liquid stored in the reagent container 160; and the volume sensor 163 is used to detect the liquid volume corresponding to the fused liquid stored in the reagent container 160.
[0059] Optionally, when the fusion liquid flows downward into the reagent container 160 through the liquid outlet 152 of the fusion part 150, the concentration sensor 162 and the volume sensor 163 on the reagent container 160 can detect the liquid concentration and liquid volume of the fusion liquid stored in the reagent container 160 in real time until the liquid concentration and liquid volume respectively detected by the concentration sensor 162 and the liquid volume of the volume sensor 163 do not change, that is, the liquid concentration and liquid volume of the fusion liquid obtained by liquid fusion through the fusion part 150.
[0060] Exemplarily, when the concentration sensor 162 detects that the liquid concentration corresponding to the fusion liquid stored in the reagent container 160 is the same as the target concentration corresponding to the target reagent, and the volume sensor 163 detects that the liquid volume corresponding to the fusion liquid stored in the reagent container 160 is the same as the target volume corresponding to the target reagent, the fusion liquid is the target reagent, the reagent configuration process of the reagent configuration device 100 is completed, and the target reagent is obtained.
[0061] Exemplarily, when the concentration sensor 162 detects that the liquid concentration corresponding to the fusion liquid stored in the reagent container 160 is the same as the target concentration corresponding to the target reagent, and / or the volume sensor 163 detects that the liquid volume corresponding to the fusion liquid stored in the reagent container 160 is the same as the target volume corresponding to the target reagent, the fusion liquid is not the target reagent, and the reagent configuration device 100 re-performs the reagent configuration process until the fusion liquid is the target reagent.
[0062] Optionally, the reagent container 160 is detachably connected to the liquid outlet 152 of the fusion portion 150 .
[0063] In some embodiments, the reagent configuration device 100 may further include a third switch, which is located between the liquid outlet 152 of the fusion part 150 and the liquid inlet 161 of the reagent container 160, and the third switch is used to control the flow of the fusion liquid stored in the fusion part 150. Specifically, the third switch is turned on only when the fusion part 150 completes the fusion of N kinds of liquids to be fused, and the reagent container 160 is successfully connected to the liquid outlet 152 of the fusion part 150, and the third switch before this is in a closed state, so that the target reagent that has been fused flows from the fusion part 150 into the reagent container 160; after all the liquids in the fusion part 150 flow into the reagent container 160, the third switch is turned off.
[0064] In a further embodiment, Figure 5 It is a schematic diagram of the structure of a reagent configuration device in another embodiment.
[0065] In some embodiments, in addition to including N liquid storage tubes 110, N first switches 120, N conduits 130, second switches 140, fusion parts 150, stirring tools 153, and reagent containers 160, the reagent configuration device 100 may also include a control module 170 and a touch display panel 180. The control module 170 is used to control the N first switches 120 to be turned on or off; and to control the second switch 140 to be turned on or off. The touch display panel 180 is used to display configuration information and touch controls; the configuration information includes parameter information of the liquid to be fused during the reagent configuration process; the touch controls are used to trigger the reagent configuration device 100 to start the reagent configuration process.
[0066] Optionally, the touch display panel 180 can also be used to display the reagent configuration process. For example, the touch display panel 180 can display in real time the current measurement of N kinds of liquids to be fused. Optionally, the touch display panel 180 can also display whether the N first switches 120 are respectively turned on or off.
[0067] In some embodiments, the touch display panel 180 can also be used to display the reagent names or IDs of all reagents that can be configured by the reagent configuration device 100 for selection by the detection technician. The detection technician can select or input the target volume and target concentration corresponding to the target reagent on the touch display panel 180 of the reagent configuration device 100.
[0068] Exemplarily, the touch display panel 180 can also be used to display the metering process of N kinds of liquids to be fused; for example, the real-time temperature of each liquid storage tube 110 and each conduit 130, the real-time flow rate of the flow sensor on the first switch 120, the real-time liquid volume detected by each conduit 130, the opening and closing status of each first switch 120 and second switch 140, etc. The touch display panel 180 can enable the detection technician to more intuitively determine the configuration process of the current target reagent.
[0069] In a further embodiment, Figure 6 FIG. 1 is a flow chart of a reagent configuration device 100 configuring a target reagent in one embodiment. Figure 6 As shown, the solid line is the control operation related to the control module 170, and the dotted line is the flow of the liquid. When the touch control of the touch display panel 180 is triggered, the reagent configuration device 100 starts the process of configuring the target reagent:
[0070] Assume that there are N liquids to be fused and corresponding configuration volumes (assuming N is 2) of the target reagent, and the two liquids to be fused are liquid A to be fused and liquid B to be fused. In the reagent configuration device 100, liquid A to be fused is stored in a liquid storage tube 110A, which is connected to a first switch 120A, which is connected to a conduit 130A; liquid B to be fused is stored in a liquid storage tube 110B, which is connected to a first switch 120B, which is connected to a conduit 130B.
[0071] When the touch control of the touch display panel 180 is triggered, the control module 170 controls the first switch 120A and the first switch 120B to be turned on, so that the liquid A to be fused in the liquid storage tube 110A flows into the conduit 130A. The conduit 130A detects the liquid volume corresponding to the liquid A to be fused stored in the conduit 130A in real time, and feeds back to the control module 170 in real time. When it is determined that the liquid volume fed back by the conduit 130A is the same as the configuration volume corresponding to the liquid A to be fused, the control module 170 controls the first switch 120A to be turned off. When the first switch 120A and the first switch 120B are both turned off, the control module 170 controls the second switch 140 to be turned on, so that the liquid A to be fused stored in the conduit 130A and the liquid B to be fused stored in the conduit 130B flow into the fusion part 150 of the reagent configuration device 100 for liquid fusion; the fusion liquid obtained by the liquid fusion in the fusion part 150 can flow from the fusion part 150 into the reagent container 160.
[0072] Optionally, the control module 170 can also be used to receive the detection results of the concentration sensor 162 and the volume sensor 163 of the reagent container 160, and the detection results are used to indicate whether the fusion liquid obtained by the fusion of the liquid by the fusion unit 150 is the target reagent. If the feedback result is that the fusion liquid is the target reagent, the reagent configuration device 100 completes the configuration of the target reagent; if the feedback result is that the fusion liquid is not the target reagent, the configuration of the target reagent is not completed, and the reagent configuration device 100 can reconfigure the target reagent or continue to configure the target reagent based on the original fusion liquid.
[0073] In some embodiments, before the reagent configuration device 100 configures the target reagent, the control module 170 can control the N first switches 120 and the second switch 140 to be closed to detect the air tightness of the reagent configuration device 100. When the air tightness meets the standard, the reagent configuration device 100 configures the target reagent. It can ensure that there is no gas leakage during the configuration process, avoid inaccurate liquid concentration caused by gas leakage, or affect the configuration of the target reagent by reaction between gas and liquid, and avoid accidental leakage of toxic, harmful or flammable and explosive reagents, etc., which can improve the safety and accuracy of reagent configuration.
[0074] In some embodiments, in order to ensure the effective operation and long-term stability of each functional element of the reagent configuration device 100, it is necessary to regularly perform quality inspection on each functional element of the reagent configuration device 100. For example, the reagent configuration device 100 is regularly cleaned and maintained to remove dust and dirt, etc.; the performance of the functional elements is evaluated, such as the measurement range, accuracy, and response time of the flow sensor or the N conduits 130, and the response rate of the N first switches 120 and the second switch 140. After the quality inspection process is recorded in detail and a quality inspection report is formed, each quality inspection report can be stored in the control module for reference or when the functional element is modified.
[0075] In some embodiments, since part of the liquid to be fused needs to be processed at a variable temperature to be configured into a target reagent, or part of the liquid to be fused has a storage temperature requirement, the reagent configuration device 100 may include a temperature regulating module, which can control the temperature of components such as the N liquid storage tubes 110, the N conduits 130, and the fusion part 150, so that the temperature can meet the storage and reaction requirements of the liquid to be fused. Optionally, the temperatures of different components may be different.
[0076] Optionally, the touch display panel 180 may be used to display the temperature of each component of the reagent configuration device 100 , and to display a temperature control, which may be used to adjust the temperature of each component of the reagent configuration device 100 .
[0077] In some embodiments, the reagent configuration device 100 may further include a reagent formula table; the reagent configuration formula table includes configuration formulas of various experimental reagents, and is used to introduce various liquids to be fused that can be configured into experimental reagents.
[0078] In some embodiments, since different combinations of liquids to be fused can be configured into the same experimental reagent, the control module 170 can also be used to screen from the preset reagent configuration formula table to determine the target formula corresponding to the target reagent that best meets the configuration conditions; the target formula includes N kinds of liquids to be fused that can be configured into the target reagent. Configuration conditions refer to a series of standards and factors used to evaluate and screen different target formulas to find the most suitable or optimized formula. Configuration conditions may include: one or more of cost-effectiveness, safety, environmental compatibility, regulatory compliance, etc., wherein cost-effectiveness refers to comparing the costs of different formulas, including raw material costs, processing costs, and possible waste costs, etc., giving priority to the feasible formula with the lowest cost; safety refers to considering the safety impact of the formula on the operator or reagent configuration equipment, as well as the possible harmful byproducts or waste; environmental compatibility refers to considering whether the environment required for the storage and reaction of various liquids to be fused in the formula can be provided by the current reagent configuration equipment 100, and whether it will have an impact on the environment, such as whether harmful wastewater, waste gas or solid waste is generated, and whether more environmentally friendly alternatives can be used; regulatory compliance refers to ensuring that the selected formula meets all relevant regulatory requirements.
[0079] Optionally, even if two target reagents of the same reagent type but different target concentrations have different corresponding formulas. For example, for both sodium chloride, a 40% sodium chloride solution can be prepared using a 60% sodium chloride solution and water, but an 80% sodium chloride solution cannot be prepared using only a 60% sodium chloride solution and water. Therefore, when determining the target formula, the target concentration corresponding to the target reagent also needs to be considered.
[0080] Optionally, the reagent configuration device 100 may determine N kinds of liquids to be fused that can be configured into the target reagent according to the target formula.
[0081] In some embodiments, the N kinds of liquids to be fused may include a liquid constituting a target reagent, which may be a solution directly containing a component of the target reagent (the target reagent is obtained by concentration changes), or a solution that can form a target reagent after a certain chemical reaction. Optionally, if the target reagent can be obtained by diluting a high-concentration solution, the N kinds of liquids to be fused may include a high-concentration solution and water corresponding to the target reagent. Optionally, if the target reagent can be obtained by increasing the concentration of a low-concentration solution, the N kinds of liquids to be fused may include a low-concentration solution and a high-concentration solution corresponding to the target reagent, and the target reagent is obtained by increasing the concentration of the low-concentration solution. For example, when the target reagent is a 60% alcohol solution, the liquid to be fused may be a 78% alcohol solution and water, or may be a 90% alcohol solution and a 40% alcohol solution.
[0082] Optionally, the N liquids to be fused may also include at least two solutions capable of producing chemical reactions, and the target reagent is generated by a chemical reaction of the N liquids to be fused. For example, sodium hydroxide and dilute hydrochloric acid react to produce sodium chloride and water, that is, when the target reagent required is a sodium chloride solution, the liquids to be fused may be sodium hydroxide and dilute hydrochloric acid.
[0083] Optionally, the liquid storage tube 110 may have a liquid identification for identifying the liquid to be fused stored in the liquid storage tube 110, wherein the liquid identification may be in the form of a barcode, a QR code, or an RFID (Radio Frequency Identification) tag, etc. The liquid identification can uniquely identify each liquid storage tube 110, and record liquid information such as the type, batch, and expiration date of the liquid to be fused stored in each liquid storage tube 110.
[0084] In some embodiments, since the liquid storage tube 110 is detachably connected to the corresponding first switch 120, and the liquid storage tube 110 has a liquid identifier that identifies the liquid to be fused stored in the liquid storage tube 110. Therefore, the reagent configuration device 100 may include a sensor or a scanning device for identifying the liquid identifier corresponding to the liquid storage tube 110. Specifically, after determining that the liquid to be fused stored in each liquid storage tube 110 is valid according to the liquid information recorded in the first liquid identifiers corresponding to the N liquid storage tubes 110, the reagent configuration device 100 starts the reagent configuration process. If there is an invalid liquid to be fused in the N liquid storage tubes 110, the touch display panel 180 may display an invalid replacement prompt to prompt the detection technician to replace the liquid storage tube 110 storing the invalid liquid to be fused. Optionally, the replacement prompt may include the liquid storage tube to be replaced and the target liquid storage tube to prompt the detection technician to disassemble and replace the liquid storage tube to be replaced with the target liquid storage tube, thereby ensuring the accuracy of the liquid to be fused.
[0085] It should be understood that the "one embodiment" or "an embodiment" mentioned throughout the specification means that the specific features, structures or characteristics related to the embodiment are included in at least one embodiment of the present application. Therefore, "in one embodiment" or "in an embodiment" appearing throughout the specification does not necessarily refer to the same embodiment. In addition, these specific features, structures or characteristics can be combined in one or more embodiments in any suitable manner. Those skilled in the art should also be aware that the embodiments described in the specification are all optional embodiments, and the actions and modules involved are not necessarily required for the present application.
[0086] In the various embodiments of the present application, it should be understood that the size of the serial numbers of the above-mentioned processes does not necessarily mean the order of execution. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiments of the present application.
[0087] The technical features of the above embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0088] The units described above as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.
[0089] In addition, each functional unit in each embodiment of the present application may be integrated into one processing unit, or each unit may exist physically separately, or two or more units may be integrated into one unit. The above-mentioned integrated unit may be implemented in the form of hardware or in the form of software functional units.
[0090] If the above-mentioned integrated unit is implemented in the form of a software functional unit and sold or used as an independent product, it can be stored in a computer-accessible memory. Based on this understanding, the technical solution of the present application, in essence, or the part that contributes to the prior art, or all or part of the technical solution, can be embodied in the form of a software product, which is stored in a memory and includes several requests for a computer device (which can be a personal computer, a server or a network device, etc., specifically a processor in a computer device) to execute some or all of the above steps of the various embodiments of the present application.
[0091] Those skilled in the art can understand that all or part of the steps in the above embodiments can be completed by instructing related hardware through a program, and the program can be stored in a computer-readable storage medium, and the storage medium includes a read-only memory (ROM), a random access memory (RAM), a programmable read-only memory (PROM), an erasable programmable read-only memory (EPROM), a one-time programmable read-only memory (OTPROM), an electronically erasable programmable read-only memory (EEPROM), a compact disc (CD-ROM) or other optical disc storage, magnetic disk storage, magnetic tape storage, or any other computer-readable medium that can be used to carry or store data.
[0092] The above is a detailed introduction to a reagent configuration device disclosed in the embodiment of the present application. The principle and implementation method of the present application are described in detail using specific examples herein. The description of the above embodiments is only used to help understand the present application and its core idea. At the same time, for those of ordinary skill in the art, according to the idea of the present application, there will be changes in the specific implementation method and application scope. In summary, the content of this specification should not be understood as a limitation on the present application.
Claims
1. A reagent preparation device, characterized in that: The reagent configuration device comprises: N liquid storage tubes, used to store different liquids to be fused; N is an integer greater than 1; N catheters, the catheters are used to store the liquid to be fused, and detect the liquid volume corresponding to the liquid to be fused stored in the catheters; N first switches, the N first switches corresponding one-to-one to the N liquid storage tubes and one-to-one to the N conduits, the first switches being connected to the corresponding liquid storage tubes and to the first ends of the corresponding conduits; a second switch connected to second ends of the N conduits; a fusion part, the fusion part being connected to the second switch; the fusion part being used for merging the liquid to be fused flowing from the N conduits to the fusion part; When the first switch is turned on, the liquid to be fused in the liquid storage tube connected to the first switch flows to the catheter connected to the first switch; when the first catheter detects that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the first switch connected to the first catheter is turned off; the first catheter is any of the catheters; When the N conduits respectively detect that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the second switch is turned on to allow the liquid to be fused respectively stored in the N conduits to flow into the fusion part.
2. The reagent preparation device according to claim 1, characterized in that: The first switch includes a switch element and a flow sensor, and the flow sensor is used to detect the liquid volume corresponding to the liquid to be fused flowing from the liquid storage tube connected to the first switch to the catheter; When the first flow sensor detects that the liquid volume corresponding to the liquid to be fused is the same as the corresponding configuration volume, the first switch corresponding to the first flow sensor is closed; the first flow sensor is the flow sensor corresponding to any first switch.
3. The reagent preparation device according to claim 1, characterized in that: The liquid outlet of the fusion part is connected to a reagent container, and the reagent container is used to store the fusion liquid obtained by the liquid fusion of the fusion part.
4. The reagent preparation device according to claim 3, characterized in that: The reagent container is provided with a concentration sensor, and the concentration sensor is used to detect the liquid concentration corresponding to the fusion liquid stored in the reagent container.
5. The reagent preparation device according to claim 3, characterized in that: The reagent container is provided with a volume sensor, and the volume sensor is used to detect the liquid volume corresponding to the fusion liquid stored in the reagent container.
6. The reagent preparation device according to claim 1, characterized in that: The reagent preparation device further comprises a stirring tool, which is arranged in the fusion part and is used to stir the N kinds of liquids to be fused in the fusion part.
7. The reagent preparation device according to claim 1, characterized in that: The N liquid storage tubes are respectively detachably connected to the corresponding first switches.
8. The reagent preparation device according to claim 1, characterized in that: The reagent configuration device further includes a control module, and the control module is used to control the N first switches to be turned on or off; and to control the second switch to be turned on or off.
9. The reagent preparation device according to claim 1, characterized in that: The catheter comprises a curved section, and a corresponding bending angle of the curved section is greater than 90 degrees.
10. The reagent preparation device according to claim 1, characterized in that: The reagent configuration device also includes a touch display panel, which is used to display configuration information and touch controls; the configuration information includes parameter information of the liquid to be fused during the reagent configuration process; and the touch controls are used to trigger the reagent configuration device to start the reagent configuration process.